 Laurie Lynne Jackson-Grusby, Ph.D.
| Title | Assistant Professor of Pathology |
|---|
| Institution | Children's Hospital Boston |
|---|
| Department | Pathology |
|---|
| Address | Children's Hospital
Enders 11
320 Longwood Ave
Boston MA 02115
|
|---|
| Phone | 617/919-2104 |
|---|
| Fax | 617/730-0168 |
|---|
|
|
|
 Bibliographic
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications.
Faculty can login to make corrections and additions.
-
Puram SV, Yeung CM, Jahani-Asl A, Lin C, de la Iglesia N, Konopka G, Jackson-Grusby L, Bonni A. STAT3-iNOS Signaling Mediates EGFRvIII-Induced Glial Proliferation and Transformation. J Neurosci. 2012 Jun 6; 32(23):7806-18.
-
DesRochers TM, Shamis Y, Alt-Holland A, Kudo Y, Takata T, Wang G, Jackson-Grusby L, Garlick JA. The 3D tissue microenvironment modulates DNA methylation and E-cadherin expression in squamous cell carcinoma. Epigenetics. 2012 Jan 1; 7(1):34-46.
-
Kesari S, Jackson-Grusby L, Stiles CD. "Smad"eningly erratic: target gene methylation determines whether TGFbeta promotes or suppresses malignant glioma. Dev Cell. 2007 Mar; 12(3):324-5.
-
Lin H, Yamada Y, Nguyen S, Linhart H, Jackson-Grusby L, Meissner A, Meletis K, Lo G, Jaenisch R. Suppression of intestinal neoplasia by deletion of Dnmt3b. Mol Cell Biol. 2006 Apr; 26(8):2976-83.
-
Holm TM, Jackson-Grusby L, Brambrink T, Yamada Y, Rideout WM, Jaenisch R. Global loss of imprinting leads to widespread tumorigenesis in adult mice. Cancer Cell. 2005 Oct; 8(4):275-85.
-
Yamada Y, Jackson-Grusby L, Linhart H, Meissner A, Eden A, Lin H, Jaenisch R. Opposing effects of DNA hypomethylation on intestinal and liver carcinogenesis. Proc Natl Acad Sci U S A. 2005 Sep 20; 102(38):13580-5.
-
Ma Y, Jacobs SB, Jackson-Grusby L, Mastrangelo MA, Torres-Betancourt JA, Jaenisch R, Rasmussen TP. DNA CpG hypomethylation induces heterochromatin reorganization involving the histone variant macroH2A. J Cell Sci. 2005 Apr 15; 118(Pt 8):1607-16.
-
Gaudet F, Hodgson JG, Eden A, Jackson-Grusby L, Dausman J, Gray JW, Leonhardt H, Jaenisch R. Induction of tumors in mice by genomic hypomethylation. Science. 2003 Apr 18; 300(5618):489-92.
-
Jackson-Grusby L. Modeling cancer in mice. Oncogene. 2002 Aug 12; 21(35):5504-14.
-
Eggan K, Rode A, Jentsch I, Samuel C, Hennek T, Tintrup H, Zevnik B, Erwin J, Loring J, Jackson-Grusby L, Speicher MR, Kuehn R, Jaenisch R. Male and female mice derived from the same embryonic stem cell clone by tetraploid embryo complementation. Nat Biotechnol. 2002 May; 20(5):455-9.
-
Possemato R, Eggan K, Moeller BJ, Jaenisch R, Jackson-Grusby L. Flp recombinase regulated lacZ expression at the ROSA26 locus. Genesis. 2002 Feb; 32(2):184-6.
-
Eggan K, Akutsu H, Loring J, Jackson-Grusby L, Klemm M, Rideout WM, Yanagimachi R, Jaenisch R. Hybrid vigor, fetal overgrowth, and viability of mice derived by nuclear cloning and tetraploid embryo complementation. Proc Natl Acad Sci U S A. 2001 May 22; 98(11):6209-14.
-
Jackson-Grusby L, Beard C, Possemato R, Tudor M, Fambrough D, Csankovszki G, Dausman J, Lee P, Wilson C, Lander E, Jaenisch R. Loss of genomic methylation causes p53-dependent apoptosis and epigenetic deregulation. Nat Genet. 2001 Jan; 27(1):31-9.
-
Rideout WM, Wakayama T, Wutz A, Eggan K, Jackson-Grusby L, Dausman J, Yanagimachi R, Jaenisch R. Generation of mice from wild-type and targeted ES cells by nuclear cloning. Nat Genet. 2000 Feb; 24(2):109-10.
-
Ho IC, Kaplan MH, Jackson-Grusby L, Glimcher LH, Grusby MJ. Marking IL-4-producing cells by knock-in of the IL-4 gene. Int Immunol. 1999 Feb; 11(2):243-7.
-
Chen RZ, Pettersson U, Beard C, Jackson-Grusby L, Jaenisch R. DNA hypomethylation leads to elevated mutation rates. Nature. 1998 Sep 3; 395(6697):89-93.
-
Wynshaw-Boris A, Ryan G, Deng CX, Chan DC, Jackson-Grusby L, Larson D, Dunmore JH, Leder P. The role of a single formin isoform in the limb and renal phenotypes of limb deformity. Mol Med. 1997 Jun; 3(6):372-84.
-
Jackson-Grusby L, Laird PW, Magge SN, Moeller BJ, Jaenisch R. Mutagenicity of 5-aza-2'-deoxycytidine is mediated by the mammalian DNA methyltransferase. Proc Natl Acad Sci U S A. 1997 Apr 29; 94(9):4681-5.
-
Jackson-Grusby L, Jaenisch R. Experimental manipulation of genomic methylation. Semin Cancer Biol. 1996 Oct; 7(5):261-8.
-
Tucker KL, Beard C, Dausmann J, Jackson-Grusby L, Laird PW, Lei H, Li E, Jaenisch R. Germ-line passage is required for establishment of methylation and expression patterns of imprinted but not of nonimprinted genes. Genes Dev. 1996 Apr 15; 10(8):1008-20.
-
Laird PW, Jackson-Grusby L, Fazeli A, Dickinson SL, Jung WE, Li E, Weinberg RA, Jaenisch R. Suppression of intestinal neoplasia by DNA hypomethylation. Cell. 1995 Apr 21; 81(2):197-205.
-
Vogt TF, Jackson-Grusby L, Rush J, Leder P. Formins: phosphoprotein isoforms encoded by the mouse limb deformity locus. Proc Natl Acad Sci U S A. 1993 Jun 15; 90(12):5554-8.
-
Shida MM, Jackson-Grusby LL, Ross SR, Linzer DI. Placental-specific expression from the mouse placental lactogen II gene promoter. Proc Natl Acad Sci U S A. 1992 May 1; 89(9):3864-8.
-
Vogt TF, Jackson-Grusby L, Wynshaw-Boris AJ, Chan DC, Leder P. The same genomic region is disrupted in two transgene-induced limb deformity alleles. Mamm Genome. 1992; 3(8):431-7.
-
Mercola M, Wang CY, Kelly J, Brownlee C, Jackson-Grusby L, Stiles C, Bowen-Pope D. Selective expression of PDGF A and its receptor during early mouse embryogenesis. Dev Biol. 1990 Mar; 138(1):114-22.
-
Zeller R, Jackson-Grusby L, Leder P. The limb deformity gene is required for apical ectodermal ridge differentiation and anteroposterior limb pattern formation. Genes Dev. 1989 Oct; 3(10):1481-92.
-
Samson ML, Jackson-Grusby L, Brent R. Gene activation and DNA binding by Drosophila Ubx and abd-A proteins. Cell. 1989 Jun 16; 57(6):1045-52.
-
Cho KO, Skarnes WC, Minsk B, Palmieri S, Jackson-Grusby L, Wagner JA. Nerve growth factor regulates gene expression by several distinct mechanisms. Mol Cell Biol. 1989 Jan; 9(1):135-43.
-
Jackson-Grusby LL, Pravtcheva D, Ruddle FH, Linzer DI. Chromosomal mapping of the prolactin/growth hormone gene family in the mouse. Endocrinology. 1988 Jun; 122(6):2462-6.
-
Jackson-Grusby LL, Swiergiel J, Linzer DI. A growth-related mRNA in cultured mouse cells encodes a placental calcium binding protein. Nucleic Acids Res. 1987 Aug 25; 15(16):6677-90.
This graph shows the total number of publications by year.
Local representatives can answer questions about the Profiles website or help with editing a profile or issues with profile data. For assistance with this profile: HMS/HSDM faculty should contact Human Resources at faculty_serviceshms.harvard.edu.
|
Jackson-Grusby's Networks
Click the "See All" links for more information and interactive visualizations!
Concepts  Derived automatically from this person's publications. _
Co-Authors People in Profiles who have published with this person. _
Similar People People who share similar concepts with this person. _
Same Department
People who are also in this person's primary department.
Physical Neighbors People whose addresses are nearby this person. _
|