Contact, publication, and social network information about Harvard faculty and fellows. Harvard Catalyst Profiles
Keywords
Last Name
Institution

Mara Lorenzi, M.D.

TitleProfessor of Ophthalmology
InstitutionSchepens Eye Research Institute
DepartmentOphthalmology
AddressSchepens Eye Research Inst.
20 Staniford Street
Boston MA 02114
Phone617/912-7410
Fax617/912-0101

 Bibliographic 
 selected publications
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
List All   |   Timeline
  1. Zerbini G, Maestroni A, Palini A, Tremolada G, Lattanzio R, Maestroni S, Pastore MR, Secchi A, Bonfanti R, Gerhardinger C, Lorenzi M. Endothelial progenitor cells carrying monocyte markers are selectively abnormal in type 1 diabetic patients with early retinopathy. Diabetes. 2012 Apr; 61(4):908-14.
    View in: PubMed
  2. Tremolada G, Pierro L, de Benedetto U, Margari S, Gagliardi M, Maestranzi G, Calori G, Lorenzi M, Lattanzio R. Macular micropseudocysts in early stages of diabetic retinopathy. Retina. 2011 Jul-Aug; 31(7):1352-8.
    View in: PubMed
  3. Lorenzi M, Feke GT, Pitler L, Berisha F, Kolodjaschna J, McMeel JW. Defective myogenic response to posture change in retinal vessels of well-controlled type 1 diabetic patients with no retinopathy. Invest Ophthalmol Vis Sci. 2010 Dec; 51(12):6770-5.
    View in: PubMed
  4. Gerhardinger C, Dagher Z, Sebastiani P, Park YS, Lorenzi M. The transforming growth factor-beta pathway is a common target of drugs that prevent experimental diabetic retinopathy. Diabetes. 2009 Jul; 58(7):1659-67.
    View in: PubMed
  5. Zerbini G, Lorenzi M, Palini A. Tumor angiogenesis. N Engl J Med. 2008 Aug 14; 359(7):763; author reply 764.
    View in: PubMed
  6. Lorenzi M, Feke GT, Cagliero E, Pitler L, Schaumberg DA, Berisha F, Nathan DM, McMeel JW. Retinal haemodynamics in individuals with well-controlled type 1 diabetes. Diabetologia. 2008 Feb; 51(2):361-4.
    View in: PubMed
  7. Lorenzi M. The polyol pathway as a mechanism for diabetic retinopathy: attractive, elusive, and resilient. Exp Diabetes Res. 2007; 2007:61038.
    View in: PubMed
  8. Sun W, Oates PJ, Coutcher JB, Gerhardinger C, Lorenzi M. A selective aldose reductase inhibitor of a new structural class prevents or reverses early retinal abnormalities in experimental diabetic retinopathy. Diabetes. 2006 Oct; 55(10):2757-62.
    View in: PubMed
  9. Lorenzi M. Mechanisms and strategies for prevention in diabetic retinopathy. Curr Diab Rep. 2006 Apr; 6(2):102-7.
    View in: PubMed
  10. Sun W, Gerhardinger C, Dagher Z, Hoehn T, Lorenzi M. Aspirin at low-intermediate concentrations protects retinal vessels in experimental diabetic retinopathy through non-platelet-mediated effects. Diabetes. 2005 Dec; 54(12):3418-26.
    View in: PubMed
  11. Dagher Z, Park YS, Asnaghi V, Hoehn T, Gerhardinger C, Lorenzi M. Studies of rat and human retinas predict a role for the polyol pathway in human diabetic retinopathy. Diabetes. 2004 Sep; 53(9):2404-11.
    View in: PubMed
  12. Asnaghi V, Gerhardinger C, Hoehn T, Adeboje A, Lorenzi M. A role for the polyol pathway in the early neuroretinal apoptosis and glial changes induced by diabetes in the rat. Diabetes. 2003 Feb; 52(2):506-11.
    View in: PubMed
  13. Zhang J, Gerhardinger C, Lorenzi M. Early complement activation and decreased levels of glycosylphosphatidylinositol-anchored complement inhibitors in human and experimental diabetic retinopathy. Diabetes. 2002 Dec; 51(12):3499-504.
    View in: PubMed
  14. Romeo G, Liu WH, Asnaghi V, Kern TS, Lorenzi M. Activation of nuclear factor-kappaB induced by diabetes and high glucose regulates a proapoptotic program in retinal pericytes. Diabetes. 2002 Jul; 51(7):2241-8.
    View in: PubMed
  15. Kasof GM, Lu JJ, Liu D, Speer B, Mongan KN, Gomes BC, Lorenzi MV. Tumor necrosis factor-alpha induces the expression of DR6, a member of the TNF receptor family, through activation of NF-kappaB. Oncogene. 2001 Nov 29; 20(55):7965-75.
    View in: PubMed
  16. Lorenzi M, Gerhardinger C. Early cellular and molecular changes induced by diabetes in the retina. Diabetologia. 2001 Jul; 44(7):791-804.
    View in: PubMed
  17. Boeri D, Maiello M, Lorenzi M. Increased prevalence of microthromboses in retinal capillaries of diabetic individuals. Diabetes. 2001 Jun; 50(6):1432-9.
    View in: PubMed
  18. Gerhardinger C, McClure KD, Romeo G, Podestà F, Lorenzi M. IGF-I mRNA and signaling in the diabetic retina. Diabetes. 2001 Jan; 50(1):175-83.
    View in: PubMed
  19. Kern TS, Tang J, Mizutani M, Kowluru RA, Nagaraj RH, Romeo G, Podesta F, Lorenzi M. Response of capillary cell death to aminoguanidine predicts the development of retinopathy: comparison of diabetes and galactosemia. Invest Ophthalmol Vis Sci. 2000 Nov; 41(12):3972-8.
    View in: PubMed
  20. Podestà F, Romeo G, Liu WH, Krajewski S, Reed JC, Gerhardinger C, Lorenzi M. Bax is increased in the retina of diabetic subjects and is associated with pericyte apoptosis in vivo and in vitro. Am J Pathol. 2000 Mar; 156(3):1025-32.
    View in: PubMed
  21. Gerhardinger C, Brown LF, Roy S, Mizutani M, Zucker CL, Lorenzi M. Expression of vascular endothelial growth factor in the human retina and in nonproliferative diabetic retinopathy. Am J Pathol. 1998 Jun; 152(6):1453-62.
    View in: PubMed
  22. Mizutani M, Gerhardinger C, Lorenzi M. Müller cell changes in human diabetic retinopathy. Diabetes. 1998 Mar; 47(3):445-9.
    View in: PubMed
  23. Lopes de Faria JB, Zoukhri D, Lorenzi M. Mesangial cell abnormalities in spontaneously hypertensive rats before the onset of hypertension. Kidney Int. 1997 Aug; 52(2):387-92.
    View in: PubMed
  24. Podestá F, Roth T, Ferrara F, Cagliero E, Lorenzi M. Cytoskeletal changes induced by excess extracellular matrix impair endothelial cell replication. Diabetologia. 1997 Aug; 40(8):879-86.
    View in: PubMed
  25. Mizutani M, Kern TS, Lorenzi M. Accelerated death of retinal microvascular cells in human and experimental diabetic retinopathy. J Clin Invest. 1996 Jun 15; 97(12):2883-90.
    View in: PubMed
  26. Roy S, Lorenzi M. Early biosynthetic changes in the diabetic-like retinopathy of galactose-fed rats. Diabetologia. 1996 Jun; 39(6):735-8.
    View in: PubMed
  27. Roy S, Cagliero E, Lorenzi M. Fibronectin overexpression in retinal microvessels of patients with diabetes. Invest Ophthalmol Vis Sci. 1996 Feb; 37(2):258-66.
    View in: PubMed
  28. Cagliero E, Roth T, Taylor AW, Lorenzi M. The effects of high glucose on human endothelial cell growth and gene expression are not mediated by transforming growth factor-beta. Lab Invest. 1995 Nov; 73(5):667-73.
    View in: PubMed
  29. Zerbini G, Roth T, Podestá F, Cagliero E, Doria A, Canessa M, Lorenzi M. Activity and expression of the Na+/H+ exchanger in human endothelial cells cultured in high glucose. Diabetologia. 1995 Jul; 38(7):785-91.
    View in: PubMed
  30. Boeri D, Cagliero E, Podestá F, Lorenzi M. Vascular wall von Willebrand factor in human diabetic retinopathy. Invest Ophthalmol Vis Sci. 1994 Feb; 35(2):600-7.
    View in: PubMed
  31. Roy S, Maiello M, Lorenzi M. Increased expression of basement membrane collagen in human diabetic retinopathy. J Clin Invest. 1994 Jan; 93(1):438-42.
    View in: PubMed
  32. Roth T, Podestá F, Stepp MA, Boeri D, Lorenzi M. Integrin overexpression induced by high glucose and by human diabetes: potential pathway to cell dysfunction in diabetic microangiopathy. Proc Natl Acad Sci U S A. 1993 Oct 15; 90(20):9640-4.
    View in: PubMed
  33. Cagliero E, Forsberg H, Sala R, Lorenzi M, Eriksson UJ. Maternal diabetes induces increased expression of extracellular matrix components in rat embryos. Diabetes. 1993 Jul; 42(7):975-80.
    View in: PubMed
  34. Lorenzi MV, Trinidad AC, Zhang R, Strauss WL. Two mRNAs are transcribed from the human gene for choline acetyltransferase. DNA Cell Biol. 1992 Oct; 11(8):593-603.
    View in: PubMed
  35. Lorenzi M. Glucose toxicity in the vascular complications of diabetes: the cellular perspective. Diabetes Metab Rev. 1992 Jul; 8(2):85-103.
    View in: PubMed
  36. Lorenzi MV, Knusel B, Hefti F, Strauss WL. Nerve growth factor regulation of choline acetyltransferase gene expression in rat embryo basal forebrain cultures. Neurosci Lett. 1992 Jun 22; 140(2):185-8.
    View in: PubMed
  37. Cagliero E, Roth T, Roy S, Maiello M, Lorenzi M. Expression of genes related to the extracellular matrix in human endothelial cells. Differential modulation by elevated glucose concentrations, phorbol esters, and cAMP. J Biol Chem. 1991 Aug 5; 266(22):14244-50.
    View in: PubMed
  38. Cagliero E, Grant MB, Lorenzi M. Measurement of gene expression in human retinal microvessels by solution hybridization. Invest Ophthalmol Vis Sci. 1991 Apr; 32(5):1439-45.
    View in: PubMed
  39. Cagliero E, Roth T, Roy S, Lorenzi M. Characteristics and mechanisms of high-glucose-induced overexpression of basement membrane components in cultured human endothelial cells. Diabetes. 1991 Jan; 40(1):102-10.
    View in: PubMed
  40. Lorenzi M. The blood-brain barrier in diabetes mellitus. Adv Exp Med Biol. 1990; 274:381-90.
    View in: PubMed
Local representatives can answer questions about the Profiles website or help with editing a profile or issues with profile data. For assistance with this profile: HMS/HSDM faculty should contact Human Resources at faculty_serviceshms.harvard.edu.
Lorenzi's Networks
Click the "See All" links for more information and interactive visualizations!
Concepts
_
Co-Authors
_
Similar People
_
Same Department
Physical Neighbors
_