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Wurtman RJ. Personalized medicine strategies for managing patients with Parkinsonism and cognitive deficits. Metabolism. 2013 Jan; 62 Suppl 1:S27-9.
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van Wijk N, Watkins CJ, Hageman RJ, Sijben JC, Kamphuis PG, Wurtman RJ, Broersen LM. Combined dietary folate, vitamin B-12, and vitamin B-6 intake influences plasma docosahexaenoic acid concentration in rats. Nutr Metab (Lond). 2012; 9(1):49.
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Scheltens P, Twisk JW, Blesa R, Scarpini E, von Arnim CA, Bongers A, Harrison J, Swinkels SH, Stam CJ, de Waal H, Wurtman RJ, Wieggers RL, Vellas B, Kamphuis PJ. Efficacy of Souvenaid in mild Alzheimer's disease: results from a randomized, controlled trial. J Alzheimers Dis. 2012; 31(1):225-36.
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van Wijk N, Watkins CJ, Böhlke M, Maher TJ, Hageman RJ, Kamphuis PJ, Broersen LM, Wurtman RJ. Plasma choline concentration varies with different dietary levels of vitamins B6, B12 and folic acid in rats maintained on choline-adequate diets. Br J Nutr. 2012 May; 107(10):1408-12.
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Wurtman RJ. Non-nutritional uses of nutrients. Eur J Pharmacol. 2011 Sep; 668 Suppl 1:S10-5.
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Wurtman RJ, Cansev M, Sakamoto T, Ulus I. Nutritional modifiers of aging brain function: use of uridine and other phosphatide precursors to increase formation of brain synapses. Nutr Rev. 2010 Dec; 68 Suppl 2:S88-101.
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Wurtman RJ. Enhancing synaptogenesis in diseases characterized by deficiencies in brain synapses. Front Psychiatry. 2010; 1:147.
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Wurtman RJ. Fibromyalgia and the complex regional pain syndrome: similarities in pathophysiology and treatment. Metabolism. 2010 Oct; 59 Suppl 1:S37-40.
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Scheltens P, Kamphuis PJ, Verhey FR, Olde Rikkert MG, Wurtman RJ, Wilkinson D, Twisk JW, Kurz A. Efficacy of a medical food in mild Alzheimer's disease: A randomized, controlled trial. Alzheimers Dement. 2010 Jan; 6(1):1-10.e1.
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Mischoulon D, Pedrelli P, Wurtman J, Vangel M, Wurtman R. Report of two double-blind randomized placebo-controlled pilot studies of a carbohydrate-rich nutrient mixture for treatment of seasonal affective disorder (SAD). CNS Neurosci Ther. 2010; 16(1):13-24.
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Kamphuis PJ, Wurtman RJ. Nutrition and Alzheimer's disease: pre-clinical concepts. Eur J Neurol. 2009 Sep; 16 Suppl 1:12-8.
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Wurtman RJ, Cansev M, Ulus IH. Synapse formation is enhanced by oral administration of uridine and DHA, the circulating precursors of brain phosphatides. J Nutr Health Aging. 2009 Mar; 13(3):189-97.
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Cansev M, Marzloff G, Sakamoto T, Ulus IH, Wurtman RJ. Giving uridine and/or docosahexaenoic acid orally to rat dams during gestation and nursing increases synaptic elements in brains of weanling pups. Dev Neurosci. 2009; 31(3):181-92.
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Wurtman RJ, Cansev M, Sakamoto T, Ulus IH. Administration of docosahexaenoic acid, uridine and choline increases levels of synaptic membranes and dendritic spines in rodent brain. World Rev Nutr Diet. 2009; 99:71-96.
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Wurtman RJ, Cansev M, Sakamoto T, Ulus IH. Use of phosphatide precursors to promote synaptogenesis. Annu Rev Nutr. 2009; 29:59-87.
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Wurtman RJ. Synapse formation and cognitive brain development: effect of docosahexaenoic acid and other dietary constituents. Metabolism. 2008 Oct; 57 Suppl 2:S6-10.
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Cansev M, Ulus IH, Wang L, Maher TJ, Wurtman RJ. Restorative effects of uridine plus docosahexaenoic acid in a rat model of Parkinson's disease. Neurosci Res. 2008 Nov; 62(3):206-9.
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Holguin S, Martinez J, Chow C, Wurtman R. Dietary uridine enhances the improvement in learning and memory produced by administering DHA to gerbils. FASEB J. 2008 Nov; 22(11):3938-46.
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Khachaturian ZS, Petersen RC, Gauthier S, Buckholtz N, Corey-Bloom JP, Evans B, Fillit H, Foster N, Greenberg B, Grundman M, Sano M, Simpkins J, Schneider LS, Weiner MW, Galasko D, Hyman B, Kuller L, Schenk D, Snyder S, Thomas RG, Tuszynski MH, Vellas B, Wurtman RJ, Snyder PJ, Frank RA, Albert M, Doody R, Ferris S, Kaye J, Koo E, Morrison-Bogorad M, Reisberg B, Salmon DP, Gilman S, Mohs R, Aisen PS, Breitner JC, Cummings JL, Kawas C, Phelps C, Poirier J, Sabbagh M, Touchon J, Khachaturian AS, Bain LJ. A roadmap for the prevention of dementia: the inaugural Leon Thal Symposium. Alzheimers Dement. 2008 May; 4(3):156-63.
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Holguin S, Huang Y, Liu J, Wurtman R. Chronic administration of DHA and UMP improves the impaired memory of environmentally impoverished rats. Behav Brain Res. 2008 Aug 5; 191(1):11-6.
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Cansev M, Wurtman RJ, Sakamoto T, Ulus IH. Oral administration of circulating precursors for membrane phosphatides can promote the synthesis of new brain synapses. Alzheimers Dement. 2008 Jan; 4(1 Suppl 1):S153-68.
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Sakamoto T, Cansev M, Wurtman RJ. Oral supplementation with docosahexaenoic acid and uridine-5'-monophosphate increases dendritic spine density in adult gerbil hippocampus. Brain Res. 2007 Nov 28; 1182:50-9.
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Cansev M, Wurtman RJ. Chronic administration of docosahexaenoic acid or eicosapentaenoic acid, but not arachidonic acid, alone or in combination with uridine, increases brain phosphatide and synaptic protein levels in gerbils. Neuroscience. 2007 Aug 24; 148(2):421-31.
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Richardson UI, Wurtman RJ. Polyunsaturated fatty acids stimulate phosphatidylcholine synthesis in PC12 cells. Biochim Biophys Acta. 2007 Apr; 1771(4):558-63.
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Wang L, Maher TJ, Wurtman RJ. Oral L-glutamine increases GABA levels in striatal tissue and extracellular fluid. FASEB J. 2007 Apr; 21(4):1227-32.
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Wang L, Albrecht MA, Wurtman RJ. Dietary supplementation with uridine-5'-monophosphate (UMP), a membrane phosphatide precursor, increases acetylcholine level and release in striatum of aged rat. Brain Res. 2007 Feb 16; 1133(1):42-8.
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Teather LA, Wurtman RJ. Chronic administration of UMP ameliorates the impairment of hippocampal-dependent memory in impoverished rats. J Nutr. 2006 Nov; 136(11):2834-7.
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Wurtman RJ. Narcolepsy and the hypocretins. Metabolism. 2006 Oct; 55(10 Suppl 2):S36-9.
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Wurtman R. Ramelteon: a novel treatment for the treatment of insomnia. Expert Rev Neurother. 2006 Jul; 6(7):957-64.
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Teather LA, Afonso VM, Wurtman RJ. Inhibition of platelet-activating factor receptors in hippocampal plasma membranes attenuates the inflammatory nociceptive response in rats. Brain Res. 2006 Jun 30; 1097(1):230-3.
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Ulus IH, Watkins CJ, Cansev M, Wurtman RJ. Cytidine and uridine increase striatal CDP-choline levels without decreasing acetylcholine synthesis or release. Cell Mol Neurobiol. 2006 Jul-Aug; 26(4-6):563-77.
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Wurtman RJ, Ulus IH, Cansev M, Watkins CJ, Wang L, Marzloff G. Synaptic proteins and phospholipids are increased in gerbil brain by administering uridine plus docosahexaenoic acid orally. Brain Res. 2006 May 9; 1088(1):83-92.
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Pooler AM, Xi SC, Wurtman RJ. The 3-hydroxy-3-methylglutaryl co-enzyme A reductase inhibitor pravastatin enhances neurite outgrowth in hippocampal neurons. J Neurochem. 2006 May; 97(3):716-23.
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Cansev M, Watkins CJ, van der Beek EM, Wurtman RJ. Oral uridine-5'-monophosphate (UMP) increases brain CDP-choline levels in gerbils. Brain Res. 2005 Oct 5; 1058(1-2):101-8.
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Wurtman RJ. Genes, stress, and depression. Metabolism. 2005 May; 54(5 Suppl 1):16-9.
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Brzezinski A, Vangel MG, Wurtman RJ, Norrie G, Zhdanova I, Ben-Shushan A, Ford I. Effects of exogenous melatonin on sleep: a meta-analysis. Sleep Med Rev. 2005 Feb; 9(1):41-50.
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Teather LA, Wurtman RJ. Dietary CDP-choline supplementation prevents memory impairment caused by impoverished environmental conditions in rats. Learn Mem. 2005 Jan-Feb; 12(1):39-43.
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Wang L, Pooler AM, Albrecht MA, Wurtman RJ. Dietary uridine-5'-monophosphate supplementation increases potassium-evoked dopamine release and promotes neurite outgrowth in aged rats. J Mol Neurosci. 2005; 27(1):137-45.
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Pooler AM, Guez DH, Benedictus R, Wurtman RJ. Uridine enhances neurite outgrowth in nerve growth factor-differentiated PC12 [corrected]. Neuroscience. 2005; 134(1):207-14.
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Arjona AA, Zhang SX, Adamson B, Wurtman RJ. An animal model of antipsychotic-induced weight gain. Behav Brain Res. 2004 Jun 4; 152(1):121-7.
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Pooler AM, Arjona AA, Lee RK, Wurtman RJ. Prostaglandin E2 regulates amyloid precursor protein expression via the EP2 receptor in cultured rat microglia. Neurosci Lett. 2004 May 20; 362(2):127-30.
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Wang P, Saraswati S, Guan Z, Watkins CJ, Wurtman RJ, Littleton JT. A Drosophila temperature-sensitive seizure mutant in phosphoglycerate kinase disrupts ATP generation and alters synaptic function. J Neurosci. 2004 May 12; 24(19):4518-29.
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Amer A, Breu J, McDermott J, Wurtman RJ, Maher TJ. 5-Hydroxy-L-tryptophan suppresses food intake in food-deprived and stressed rats. Pharmacol Biochem Behav. 2004 Jan; 77(1):137-43.
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Teather LA, Wurtman RJ. Dietary cytidine (5')-diphosphocholine supplementation protects against development of memory deficits in aging rats. Prog Neuropsychopharmacol Biol Psychiatry. 2003 Jun; 27(4):711-7.
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Richardson UI, Watkins CJ, Pierre C, Ulus IH, Wurtman RJ. Stimulation of CDP-choline synthesis by uridine or cytidine in PC12 rat pheochromocytoma cells. Brain Res. 2003 May 9; 971(2):161-7.
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Teather LA, Wurtman RJ. Cyclooxygenase-2 mediates platelet-activating factor-induced prostaglandin E2 release from rat primary astrocytes. Neurosci Lett. 2003 Apr 17; 340(3):177-80.
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Wurtman RJ, Wurtman JJ, Regan MM, McDermott JM, Tsay RH, Breu JJ. Effects of normal meals rich in carbohydrates or proteins on plasma tryptophan and tyrosine ratios. Am J Clin Nutr. 2003 Jan; 77(1):128-32.
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Teather LA, Magnusson JE, Chow CM, Wurtman RJ. Environmental conditions influence hippocampus-dependent behaviours and brain levels of amyloid precursor protein in rats. Eur J Neurosci. 2002 Dec; 16(12):2405-15.
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Arjona AA, Pooler AM, Lee RK, Wurtman RJ. Effect of a 5-HT(2C) serotonin agonist, dexnorfenfluramine, on amyloid precursor protein metabolism in guinea pigs. Brain Res. 2002 Sep 27; 951(1):135-40.
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Teather LA, Lee RK, Wurtman RJ. Platelet-activating factor increases prostaglandin E(2) release from astrocyte-enriched cortical cell cultures. Brain Res. 2002 Aug 9; 946(1):87-95.
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Wurtman RJ. Stress and the adrenocortical control of epinephrine synthesis. Metabolism. 2002 Jun; 51(6 Suppl 1):11-4.
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Teather LA, Magnusson JE, Wurtman RJ. Platelet-activating factor antagonists decrease the inflammatory nociceptive response in rats. Psychopharmacology (Berl). 2002 Oct; 163(3-4):430-3.
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Wurtman JJ, McDermott JM, Levendusky P, Duca K, Wurtman R. The effect of a novel dietary intervention on weight loss in psychotropic drug-induced obesity. Psychopharmacol Bull. 2002; 36(3):55-9.
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Zhdanova IV, Wurtman RJ, Regan MM, Taylor JA, Shi JP, Leclair OU. Melatonin treatment for age-related insomnia. J Clin Endocrinol Metab. 2001 Oct; 86(10):4727-30.
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Wurtman RJ, Regan M, Ulus I, Yu L. Effect of oral CDP-choline on plasma choline and uridine levels in humans. Biochem Pharmacol. 2000 Oct 1; 60(7):989-92.
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Balcioglu A, Wurtman RJ. Sibutramine, a serotonin uptake inhibitor, increases dopamine concentrations in rat striatal and hypothalamic extracellular fluid. Neuropharmacology. 2000 Sep; 39(12):2352-9.
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Balcioglu A, Wurtman RJ. Striatal serotonin receptors and dopamine release. J Neurochem. 2000 Aug; 75(2):886.
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Ulus IH, Maher TJ, Wurtman RJ. Characterization of phentermine and related compounds as monoamine oxidase (MAO) inhibitors. Biochem Pharmacol. 2000 Jun 15; 59(12):1611-21.
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Wurtman RJ. Age-related decreases in melatonin secretion--clinical consequences. J Clin Endocrinol Metab. 2000 Jun; 85(6):2135-6.
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Wang C, Wurtman RJ, Lee RK. Amyloid precursor protein and membrane phospholipids in primary cortical neurons increase with development, or after exposure to nerve growth factor or Abeta(1-40). Brain Res. 2000 May 26; 865(2):157-67.
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Agut J, Ortiz JA, Wurtman RJ. Cytidine (5')diphosphocholine modulates dopamine K(+)-evoked release in striatum measured by microdialysis. Ann N Y Acad Sci. 2000; 920:332-5.
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Lee RK, Wurtman RJ. Regulation of APP synthesis and secretion by neuroimmunophilin ligands and cyclooxygenase inhibitors. Ann N Y Acad Sci. 2000; 920:261-8.
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Young MJ, Lee RK, Jhaveri S, Wurtman RJ. Intracellular and cell-surface distribution of amyloid precursor protein in cortical astrocytes. Brain Res Bull. 1999 Sep 1; 50(1):27-32.
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Wurtman RJ. [Neuronal death mechanisms in cerebral ischemia: laboratory at the clinic]. Rev Neurol. 1999 Sep 16-30; 29(6):524-6.
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Li J, Wurtman RJ. Heterogeneous long chain acyl-CoA synthetases control distribution of individual fatty acids in newly-formed glycerolipids of neuronal cells undergoing neurite outgrowth. Neurochem Res. 1999 Jun; 24(6):739-50.
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Knapp S, Wurtman RJ. Enhancement of free fatty acid incorporation into phospholipids by choline plus cytidine. Brain Res. 1999 Mar 20; 822(1-2):52-9.
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Li J, Wurtman RJ. Mechanisms whereby nerve growth factor increases diacylglycerol levels in differentiating PC12 cells. Brain Res. 1999 Feb 13; 818(2):252-9.
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Lee RK, Knapp S, Wurtman RJ. Prostaglandin E2 stimulates amyloid precursor protein gene expression: inhibition by immunosuppressants. J Neurosci. 1999 Feb 1; 19(3):940-7.
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Maher TJ, Ulus IH, Wurtman RJ. Phentermine and other monoamine-oxidase inhibitors may increase plasma serotonin when given with fenfluramines. Lancet. 1999 Jan 2; 353(9146):38.
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Zhdanova IV, Wurtman RJ, Wagstaff J. Effects of a low dose of melatonin on sleep in children with Angelman syndrome. J Pediatr Endocrinol Metab. 1999 Jan-Feb; 12(1):57-67.
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Balcioglu A, Wurtman RJ. Effects of fenfluramine and phentermine (fen-phen) on dopamine and serotonin release in rat striatum: in vivo microdialysis study in conscious animals. Brain Res. 1998 Nov 30; 813(1):67-72.
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Li J, Wurtman RJ. Nerve growth factor stimulates diacylglycerol de novo synthesis and phosphatidylinositol hydrolysis in pheochromocytoma cells. Brain Res. 1998 Aug 24; 803(1-2):44-53.
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Zhdanova IV, Wurtman RJ, Balcioglu A, Kartashov AI, Lynch HJ. Endogenous melatonin levels and the fate of exogenous melatonin: age effects. J Gerontol A Biol Sci Med Sci. 1998 Jul; 53(4):B293-8.
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Wurtman RJ, Zhdanova II. Oral melatonin in neurologically disabled children. Lancet. 1998 Jun 27; 351(9120):1963-4; author reply 1964.
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Araki W, Wurtman RJ. Increased expression of amyloid precursor protein and amyloid precursor-like protein 2 during trophic factor withdrawal-induced death of neuronal PC12 cells. Brain Res Mol Brain Res. 1998 May; 56(1-2):169-77.
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Balcioglu A, Wurtman RJ. Effects of phentermine on striatal dopamine and serotonin release in conscious rats: in vivo microdialysis study. Int J Obes Relat Metab Disord. 1998 Apr; 22(4):325-8.
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Araki W, Wurtman RJ. How is membrane phospholipid biosynthesis controlled in neural tissues? J Neurosci Res. 1998 Mar 15; 51(6):667-74.
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Balcioglu A, Wurtman RJ. Dexfenfluramine enhances striatal dopamine release in conscious rats via a serotoninergic mechanism. J Pharmacol Exp Ther. 1998 Mar; 284(3):991-7.
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Müller D, Nitsch RM, Wurtman RJ, Hoyer S. Streptozotocin increases free fatty acids and decreases phospholipids in rat brain. J Neural Transm. 1998; 105(10-12):1271-81.
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Zhdanova IV, Cantor ML, Leclair OU, Kartashov AI, Wurtman RJ. Behavioral effects of melatonin treatment in non-human primates. Sleep Res Online. 1998; 1(3):114-8.
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Zhdanova IV, Wurtman RJ. Efficacy of melatonin as a sleep-promoting agent. J Biol Rhythms. 1997 Dec; 12(6):644-50.
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Araki W, Wurtman RJ. Control of membrane phosphatidylcholine biosynthesis by diacylglycerol levels in neuronal cells undergoing neurite outgrowth. Proc Natl Acad Sci U S A. 1997 Oct 28; 94(22):11946-50.
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McPhie DL, Lee RK, Eckman CB, Olstein DH, Durham SP, Yager D, Younkin SG, Wurtman RJ, Neve RL. Neuronal expression of beta-amyloid precursor protein Alzheimer mutations causes intracellular accumulation of a C-terminal fragment containing both the amyloid beta and cytoplasmic domains. J Biol Chem. 1997 Oct 3; 272(40):24743-6.
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Zhdanova IV, Lynch HJ, Wurtman RJ. Melatonin: a sleep-promoting hormone. Sleep. 1997 Oct; 20(10):899-907.
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Slack BE, Breu J, Muchnicki L, Wurtman RJ. Rapid stimulation of amyloid precursor protein release by epidermal growth factor: role of protein kinase C. Biochem J. 1997 Oct 1; 327 ( Pt 1):245-9.
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Conlay LA, Conant JA, deBros F, Wurtman R. Caffeine alters plasma adenosine levels. Nature. 1997 Sep 11; 389(6647):136.
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Nitsch RM, Deng A, Wurtman RJ, Growdon JH. Metabotropic glutamate receptor subtype mGluR1alpha stimulates the secretion of the amyloid beta-protein precursor ectodomain. J Neurochem. 1997 Aug; 69(2):704-12.
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Wurtman RJ. What went right: why is HIV a treatable infection? Nat Med. 1997 Jul; 3(7):714-7.
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Fernstrom JD, Wurtman RJ. Brain serotonin content: physiological regulation by plasma neutral amino acids. 1971. Obes Res. 1997 Jul; 5(4):377-80.
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Lee RK, Araki W, Wurtman RJ. Stimulation of amyloid precursor protein synthesis by adrenergic receptors coupled to cAMP formation. Proc Natl Acad Sci U S A. 1997 May 13; 94(10):5422-6.
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Lee RK, Wurtman RJ. Metabotropic glutamate receptors increase amyloid precursor protein processing in astrocytes: inhibition by cyclic AMP. J Neurochem. 1997 May; 68(5):1830-5.
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Erfurth A, Wurtman RJ. Sensitive measurement of agonist-stimulated [3H]inositol monophosphate accumulation in rat cortical miniprisms. Brain Res Brain Res Protoc. 1997 May; 1(2):139-44.
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Ulus IH, Wurtman RJ. Metabotropic glutamate receptor agonists increase release of soluble amyloid precursor protein derivatives from rat brain cortical and hippocampal slices. J Pharmacol Exp Ther. 1997 Apr; 281(1):149-54.
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Bogdanov MB, Wurtman RJ. Possible involvement of nitric oxide in NMDA-induced glutamate release in the rat striatum: an in vivo microdialysis study. Neurosci Lett. 1997 Jan 17; 221(2-3):197-201.
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Petryniak MA, Wurtman RJ, Slack BE. Elevated intracellular calcium concentration increases secretory processing of the amyloid precursor protein by a tyrosine phosphorylation-dependent mechanism. Biochem J. 1996 Dec 15; 320 ( Pt 3):957-63.
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Bogdanov MB, Tjurmina OA, Wurtman RJ. Consumption of a high dietary dose of monosodium glutamate fails to affect extracellular glutamate levels in the hypothalamic arcuate nucleus of adult rats. Brain Res. 1996 Oct 14; 736(1-2):76-81.
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Babb SM, Appelmans KE, Renshaw PF, Wurtman RJ, Cohen BM. Differential effect of CDP-choline on brain cytosolic choline levels in younger and older subjects as measured by proton magnetic resonance spectroscopy. Psychopharmacology (Berl). 1996 Sep; 127(2):88-94.
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Farber SA, Savci V, Wei A, Slack BE, Wurtman RJ. Choline's phosphorylation in rat striatal slices is regulated by the activity of cholinergic neurons. Brain Res. 1996 Jun 3; 723(1-2):90-9.
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Zhdanova IV, Wurtman RJ, Morabito C, Piotrovska VR, Lynch HJ. Effects of low oral doses of melatonin, given 2-4 hours before habitual bedtime, on sleep in normal young humans. Sleep. 1996 Jun; 19(5):423-31.
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Spiers PA, Myers D, Hochanadel GS, Lieberman HR, Wurtman RJ. Citicoline improves verbal memory in aging. Arch Neurol. 1996 May; 53(5):441-8.
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Wurtman RJ. What is leptin for, and does it act on the brain? Nat Med. 1996 May; 2(5):492-3.
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Spedding M, Ouvry C, Millan M, Duhault J, Dacquet C, Wurtman R. Neural control of dieting. Nature. 1996 Apr 11; 380(6574):488.
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Marshall DL, De Micheli E, Bogdanov MB, Wurtman RJ. Effects of ethanolamine (Etn) administration on Etn and choline (Ch) levels in plasma, brain extracellular fluid (ECF) and brain tissue, and on brain phospholipid levels in rats: an in vivo study. Neurosci Res Commun. 1996 Mar-Apr; 18(2):87-96.
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Nitsch RM, Deng M, Growdon JH, Wurtman RJ. Serotonin 5-HT2a and 5-HT2c receptors stimulate amyloid precursor protein ectodomain secretion. J Biol Chem. 1996 Feb 23; 271(8):4188-94.
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Nitsch RM, Wurtman RJ, Growdon JH. Regulation of APP processing. Potential for the therapeutical reduction of brain amyloid burden. Ann N Y Acad Sci. 1996 Jan 17; 777:175-82.
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Lee RK, Jimenez J, Cox AJ, Wurtman RJ. Metabotropic glutamate receptors regulate APP processing in hippocampal neurons and cortical astrocytes derived from fetal rats. Ann N Y Acad Sci. 1996 Jan 17; 777:338-43.
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Wurtman RJ, Wurtman JJ. Brain Serotonin, Carbohydrate-craving, obesity and depression. Adv Exp Med Biol. 1996; 398:35-41.
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Wurtman RJ, Zhdanova I. Improvement of sleep quality by melatonin. Lancet. 1995 Dec 2; 346(8988):1491.
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Spring B, Wurtman J, Wurtman R, el-Khoury A, Goldberg H, McDermott J, Pingitore R. Efficacies of dexfenfluramine and fluoxetine in preventing weight gain after smoking cessation. Am J Clin Nutr. 1995 Dec; 62(6):1181-7.
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Wurtman RJ, Bettiker RL. The slowing of treatment discovery, 1965-1995. Nat Med. 1995 Nov; 1(11):1122-5.
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Farber SA, Nitsch RM, Schulz JG, Wurtman RJ. Regulated secretion of beta-amyloid precursor protein in rat brain. J Neurosci. 1995 Nov; 15(11):7442-51.
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Wurtman RJ, Wurtman JJ. Brain serotonin, carbohydrate-craving, obesity and depression. Obes Res. 1995 Nov; 3 Suppl 4:477S-480S.
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Sayegh R, Schiff I, Wurtman J, Spiers P, McDermott J, Wurtman R. The effect of a carbohydrate-rich beverage on mood, appetite, and cognitive function in women with premenstrual syndrome. Obstet Gynecol. 1995 Oct; 86(4 Pt 1):520-8.
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Cohen BM, Renshaw PF, Stoll AL, Wurtman RJ, Yurgelun-Todd D, Babb SM. Decreased brain choline uptake in older adults. An in vivo proton magnetic resonance spectroscopy study. JAMA. 1995 Sep 20; 274(11):902-7.
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Lee RK, Wurtman RJ, Cox AJ, Nitsch RM. Amyloid precursor protein processing is stimulated by metabotropic glutamate receptors. Proc Natl Acad Sci U S A. 1995 Aug 15; 92(17):8083-7.
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López-Coviella I, Agut J, Savci V, Ortiz JA, Wurtman RJ. Evidence that 5'-cytidinediphosphocholine can affect brain phospholipid composition by increasing choline and cytidine plasma levels. J Neurochem. 1995 Aug; 65(2):889-94.
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Zhdanova IV, Wurtman RJ, Lynch HJ, Ives JR, Dollins AB, Morabito C, Matheson JK, Schomer DL. Sleep-inducing effects of low doses of melatonin ingested in the evening. Clin Pharmacol Ther. 1995 May; 57(5):552-8.
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Slack BE, Breu J, Petryniak MA, Srivastava K, Wurtman RJ. Tyrosine phosphorylation-dependent stimulation of amyloid precursor protein secretion by the m3 muscarinic acetylcholine receptor. J Biol Chem. 1995 Apr 7; 270(14):8337-44.
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Nitsch RM, Rebeck GW, Deng M, Richardson UI, Tennis M, Schenk DB, Vigo-Pelfrey C, Lieberburg I, Wurtman RJ, Hyman BT, et al. Cerebrospinal fluid levels of amyloid beta-protein in Alzheimer's disease: inverse correlation with severity of dementia and effect of apolipoprotein E genotype. Ann Neurol. 1995 Apr; 37(4):512-8.
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Nitsch RM, Wurtman RJ, Growdon JH. Regulation of proteolytic processing of the amyloid beta-protein precursor by first messengers. A novel potential approach for the treatment of Alzheimer's disease. Arzneimittelforschung. 1995 Mar; 45(3A):435-8.
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Stoll AL, Renshaw PF, De Micheli E, Wurtman R, Pillay SS, Cohen BM. Choline ingestion increases the resonance of choline-containing compounds in human brain: an in vivo proton magnetic resonance study. Biol Psychiatry. 1995 Feb 1; 37(3):170-4.
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Dollins AB, Krock LP, Storm WF, Wurtman RJ, Lieberman HR. L-tyrosine ameliorates some effects of lower body negative pressure stress. Physiol Behav. 1995 Feb; 57(2):223-30.
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Slack BE, Breu J, Livneh E, Eldar H, Wurtman RJ. Phorbol ester stimulates choline uptake in Swiss 3T3 fibroblasts following introduction of the gene encoding protein kinase C alpha. Biochem J. 1995 Jan 15; 305 ( Pt 2):621-6.
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Savci V, Wurtman RJ. Effect of cytidine on membrane phospholipid synthesis in rat striatal slices. J Neurochem. 1995 Jan; 64(1):378-84.
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Jackson DA, Kischka U, Wurtman RJ. Choline enhances scopolamine-induced acetylcholine release in dorsal hippocampus of conscious, freely-moving rats. Life Sci. 1995; 56(1):45-9.
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Erfurth A, Gardier AM, Ribeiro E, Wurtman RJ. Effects of subchronic pretreatment with D-fenfluramine or p-chloroamphetamine on [3H]inositolmonophosphate accumulation in rat cortical miniprisms. Brain Res. 1994 Nov 28; 665(1):107-14.
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Bogdanov MB, Wurtman RJ. Effects of systemic or oral ad libitum monosodium glutamate administration on striatal glutamate release, as measured using microdialysis in freely moving rats. Brain Res. 1994 Oct 17; 660(2):337-40.
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O'Rourke DA, Wurtman JJ, Wurtman RJ, Tsay R, Gleason R, Baer L, Jenike MA. Aberrant snacking patterns and eating disorders in patients with obsessive compulsive disorder. J Clin Psychiatry. 1994 Oct; 55(10):445-7.
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Wurtman RJ. The return of the cholinergic hypothesis. J Clin Invest. 1994 Aug; 94(2):470.
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Dollins AB, Zhdanova IV, Wurtman RJ, Lynch HJ, Deng MH. Effect of inducing nocturnal serum melatonin concentrations in daytime on sleep, mood, body temperature, and performance. Proc Natl Acad Sci U S A. 1994 Mar 1; 91(5):1824-8.
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Wurtman RJ, Bettiker RL. How to find a treatment for Alzheimer's disease. Neurobiol Aging. 1994; 15 Suppl 2:S179-81.
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Nitsch RM, Slack BE, Farber SA, Schulz JG, Deng M, Kim C, Borghesani PR, Korver W, Wurtman RJ, Growdon JH. Regulation of proteolytic processing of the amyloid beta-protein precursor of Alzheimer's disease in transfected cell lines and in brain slices. J Neural Transm Suppl. 1994; 44:21-7.
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Marshall DL, Wurtman RJ. Effect of choline on basal and stimulated acetylcholine release: an in vivo microdialysis study using a low neostigmine concentration. Brain Res. 1993 Dec 3; 629(2):269-74.
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Hung AY, Haass C, Nitsch RM, Qiu WQ, Citron M, Wurtman RJ, Growdon JH, Selkoe DJ. Activation of protein kinase C inhibits cellular production of the amyloid beta-protein. J Biol Chem. 1993 Nov 5; 268(31):22959-62.
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Wurtman J, Wurtman R, Berry E, Gleason R, Goldberg H, McDermott J, Kahne M, Tsay R. Dexfenfluramine, fluoxetine, and weight loss among female carbohydrate cravers. Neuropsychopharmacology. 1993 Nov; 9(3):201-10.
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Nitsch RM, Blusztajn JK, Doyle FM, Robitaille Y, Wurtman RJ, Growdon JH, Kish SJ. Phospholipid metabolite levels are altered in cerebral cortex of patients with dominantly inherited olivopontocerebellar atrophy. Neurosci Lett. 1993 Oct 29; 161(2):191-4.
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Slack BE, Nitsch RM, Livneh E, Kunz GM, Breu J, Eldar H, Wurtman RJ. Regulation by phorbol esters of amyloid precursor protein release from Swiss 3T3 fibroblasts overexpressing protein kinase C alpha. J Biol Chem. 1993 Oct 5; 268(28):21097-101.
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Slack BE, Nitsch RM, Livneh E, Kunz GM, Eldar H, Wurtman RJ. Regulation of amyloid precursor protein release by protein kinase C in Swiss 3T3 fibroblasts. Ann N Y Acad Sci. 1993 Sep 24; 695:128-31.
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Nitsch RM, Slack BE, Farber SA, Borghesani PR, Schulz JG, Kim C, Felder CC, Growdon JH, Wurtman RJ. Receptor-coupled amyloid precursor protein processing. Ann N Y Acad Sci. 1993 Sep 24; 695:122-7.
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Holmes TC, Nitsch RM, Erfurth A, Wurtman RJ. Phospholipid and phospholipid metabolites in rat frontal cortex are decreased following nucleus basalis lesions. Ann N Y Acad Sci. 1993 Sep 24; 695:241-3.
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Agut J, Lopez G-Coviella I, Ortiz JA, Wurtman RJ. Oral cytidine 5'-diphosphate choline administration to rats increases brain phospholipid levels. Ann N Y Acad Sci. 1993 Sep 24; 695:318-20.
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Ribeiro EB, Bettiker RL, Bogdanov M, Wurtman RJ. Effects of systemic nicotine on serotonin release in rat brain. Brain Res. 1993 Sep 10; 621(2):311-8.
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Kischka U, Farber SA, Marshall D, Wurtman RJ. Carbachol and naloxone synergistically elevate dopamine release in rat striatum: an in vivo microdialysis study. Brain Res. 1993 Jun 11; 613(2):288-90.
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Nitsch RM, Farber SA, Growdon JH, Wurtman RJ. Release of amyloid beta-protein precursor derivatives by electrical depolarization of rat hippocampal slices. Proc Natl Acad Sci U S A. 1993 Jun 1; 90(11):5191-3.
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Farber SA, Kischka U, Marshall DL, Wurtman RJ. Potentiation by choline of basal and electrically evoked acetylcholine release, as studied using a novel device which both stimulates and perfuses rat corpus striatum. Brain Res. 1993 Apr 2; 607(1-2):177-84.
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Kaakkola S, Wurtman RJ. Effects of catechol-O-methyltransferase inhibitors and L-3,4-dihydroxyphenylalanine with or without carbidopa on extracellular dopamine in rat striatum. J Neurochem. 1993 Jan; 60(1):137-44.
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Lehnert H, Wurtman RJ. Amino acid control of neurotransmitter synthesis and release: physiological and clinical implications. Psychother Psychosom. 1993; 60(1):18-32.
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Dollins AB, Lynch HJ, Wurtman RJ, Deng MH, Lieberman HR. Effects of illumination on human nocturnal serum melatonin levels and performance. Physiol Behav. 1993 Jan; 53(1):153-60.
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Kaakkola S, Wurtman RJ. Effects of two diketopiperazines, cyclo (His-Pro) and cyclo (Asp-Phe), on striatal dopamine: a microdialysis study. Brain Res Bull. 1993; 32(6):667-72.
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Dollins AB, Lynch HJ, Wurtman RJ, Deng MH, Kischka KU, Gleason RE, Lieberman HR. Effect of pharmacological daytime doses of melatonin on human mood and performance. Psychopharmacology (Berl). 1993; 112(4):490-6.
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Nitsch RM, Slack BE, Wurtman RJ, Growdon JH. Release of Alzheimer amyloid precursor derivatives stimulated by activation of muscarinic acetylcholine receptors. Science. 1992 Oct 9; 258(5080):304-7.
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Conlay LA, Sabounjian LA, Wurtman RJ. Exercise and neuromodulators: choline and acetylcholine in marathon runners. Int J Sports Med. 1992 Oct; 13 Suppl 1:S141-2.
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Gardier AM, Kaakkola S, Erfurth A, Wurtman RJ. Effects of methiothepin on changes in brain serotonin release induced by repeated administration of high doses of anorectic serotoninergic drugs. Brain Res. 1992 Aug 14; 588(1):67-74.
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Kaakkola S, Wurtman RJ. Effects of COMT inhibitors on striatal dopamine metabolism: a microdialysis study. Brain Res. 1992 Aug 7; 587(2):241-9.
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Slack BE, Richardson UI, Nitsch RM, Wurtman RJ. Dioctanoylglycerol stimulates accumulation of [methyl-14C]choline and its incorporation into acetylcholine and phosphatidylcholine in a human cholinergic neuroblastoma cell line. Brain Res. 1992 Jul 10; 585(1-2):169-76.
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Richardson UI, Wurtman RJ. Base-exchange and cell growth in 3T6 mouse fibroblasts. Biochim Biophys Acta. 1992 Jul 9; 1127(1):99-102.
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G-Coviella IL, Wurtman RJ. Enhancement by cytidine of membrane phospholipid synthesis. J Neurochem. 1992 Jul; 59(1):338-43.
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Ulus IH, Buyukuysal RL, Wurtman RJ. N-methyl-D-aspartate increases acetylcholine release from rat striatum and cortex: its effect is augmented by choline. J Pharmacol Exp Ther. 1992 Jun; 261(3):1122-8.
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López G-Coviella I, Agut J, Ortiz JA, Wurtman RJ. Effects of orally administered cytidine 5'-diphosphate choline on brain phospholipid content. J Nutr Biochem. 1992 Jun; 3(6):313-5.
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Richardson UI, Wurtman RJ. Characterization of [3H]MK-801 binding in LA-N-2 neuroblastoma cells. Ann N Y Acad Sci. 1992 May 11; 648:328-9.
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Wurtman RJ. Choline metabolism as a basis for the selective vulnerability of cholinergic neurons. Trends Neurosci. 1992 Apr; 15(4):117-22.
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Nitsch RM, Blusztajn JK, Pittas AG, Slack BE, Growdon JH, Wurtman RJ. Evidence for a membrane defect in Alzheimer disease brain. Proc Natl Acad Sci U S A. 1992 Mar 1; 89(5):1671-5.
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Baumgarten G, Garattini S, Lorens S, Wurtman R. Dexfenfluramine and neurotoxicity. Lancet. 1992 Feb 8; 339(8789):359; author reply 360-1.
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Johnson DA, Ulus IH, Wurtman RJ. Caffeine potentiates the enhancement by choline of striatal acetylcholine release. Life Sci. 1992; 51(20):1597-601.
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Kaakkola S, Tuomainen P, Wurtman RJ, Männistö PT. Effects of systemic carbidopa on dopamine synthesis in rat hypothalamus and striatum. J Neural Transm Park Dis Dement Sect. 1992; 4(2):143-54.
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Wurtman RJ. Effects of foods on the brain. Possible implications for understanding and treating Tourette syndrome. Adv Neurol. 1992; 58:293-301.
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Slack BE, Breu J, Wurtman RJ. Production of diacylglycerol by exogenous phospholipase C stimulates CTP:phosphocholine cytidylyltransferase activity and phosphatidylcholine synthesis in human neuroblastoma cells. J Biol Chem. 1991 Dec 25; 266(36):24503-8.
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Deng MH, Lopez G-Coviella I, Lynch HJ, Wurtman RJ. Melatonin and its precursors in Y79 human retinoblastoma cells: effect of sodium butyrate. Brain Res. 1991 Oct 11; 561(2):274-8.
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Growdon JH, Nader TM, Schoenfeld J, Wurtman RJ. L-threonine in the treatment of spasticity. Clin Neuropharmacol. 1991 Oct; 14(5):403-12.
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Wurtman RJ. The choline-deficient diet. FASEB J. 1991 Aug; 5(11):2612.
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Berry EM, Growdon JH, Wurtman JJ, Caballero B, Wurtman RJ. A balanced carbohydrate: protein diet in the management of Parkinson's disease. Neurology. 1991 Aug; 41(8):1295-7.
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Kerstetter J, Caballero B, O'Brien K, Wurtman R, Allen L. Mineral homeostasis in obesity: effects of euglycemic hyperinsulinemia. Metabolism. 1991 Jul; 40(7):707-13.
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Caballero B, Gleason RE, Wurtman RJ. Plasma amino acid concentrations in healthy elderly men and women. Am J Clin Nutr. 1991 May; 53(5):1249-52.
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Sandmann J, Peralta EG, Wurtman RJ. Coupling of transfected muscarinic acetylcholine receptor subtypes to phospholipase D. J Biol Chem. 1991 Apr 5; 266(10):6031-4.
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Sandmann J, Wurtman RJ. Stimulation of phospholipase D activity in human neuroblastoma (LA-N-2) cells by activation of muscarinic acetylcholine receptors or by phorbol esters: relationship to phosphoinositide turnover. J Neurochem. 1991 Apr; 56(4):1312-9.
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Buyukuysal RL, Holmes TC, Wurtman RJ. Interactions of 3,4-diaminopyridine and choline in stimulating acetylcholine release and protecting membrane phospholipids. Brain Res. 1991 Feb 8; 541(1):1-6.
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Gardier AM, Wurtman RJ. Persistent blockade of potassium-evoked serotonin release from rat frontocortical terminals after fluoxetine administration. Brain Res. 1991 Feb 1; 540(1-2):325-30.
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Spring B, Wurtman J, Gleason R, Wurtman R, Kessler K. Weight gain and withdrawal symptoms after smoking cessation: a preventive intervention using d-fenfluramine. Health Psychol. 1991; 10(3):216-23.
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Kim SH, Mauron J, Gleason R, Wurtman R. Selection of carbohydrate to protein ratio and correlations with weight gain and body fat in rats allowed three dietary choices. Int J Vitam Nutr Res. 1991; 61(2):166-79.
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Nitsch R, Pittas A, Blusztajn JK, Slack BE, Growdon JH, Wurtman RJ. Alterations of phospholipid metabolites in postmortem brain from patients with Alzheimer's disease. Ann N Y Acad Sci. 1991; 640:110-3.
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Caballero B, Wurtman RJ. Differential effects of insulin resistance on leucine and glucose kinetics in obesity. Metabolism. 1991 Jan; 40(1):51-8.
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Farber SA, Buyukuysal RL, Wurtman RJ. Why do phospholipid levels decrease with repeated stimulation? A study of choline-containing compounds in rat striatum following electrical stimulation. Ann N Y Acad Sci. 1991; 640:114-7.
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Blusztajn JK, Lopez Gonzalez-Coviella I, Logue M, Growdon JH, Wurtman RJ. Levels of phospholipid catabolic intermediates, glycerophosphocholine and glycerophosphoethanolamine, are elevated in brains of Alzheimer's disease but not of Down's syndrome patients. Brain Res. 1990 Dec 17; 536(1-2):240-4.
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Kreutz MR, Acworth IN, Lehnert H, Wurtman RJ. Systemic administration of thyrotropin-releasing hormone enhances striatal dopamine release in vivo. Brain Res. 1990 Dec 17; 536(1-2):347-52.
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Schaechter JD, Wurtman RJ. Serotonin release varies with brain tryptophan levels. Brain Res. 1990 Nov 5; 532(1-2):203-10.
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Sarkissian CF, Wurtman RJ, Morse AN, Gleason R. Effects of fluoxetine or D-fenfluramine on serotonin release from, and levels in, rat frontal cortex. Brain Res. 1990 Oct 8; 529(1-2):294-301.
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Holbrook PG, Wurtman RJ. Calcium-dependent incorporation of choline into phosphatidylcholine (PC) by base-exchange in rat brain membranes occurs preferentially with phospholipid substrates containing docosahexaenoic acid (22:6(n-3)). Biochim Biophys Acta. 1990 Sep 18; 1046(2):185-8.
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Maher TJ, Kiritsy PJ, Moya-Huff FA, Casacci F, De Marchi F, Wurtman RJ. Use of parenteral dipeptides to increase serum tyrosine levels and to enhance catecholamine-mediated neurotransmission. J Pharm Sci. 1990 Aug; 79(8):685-7.
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Brzezinski AA, Wurtman JJ, Wurtman RJ, Gleason R, Greenfield J, Nader T. d-Fenfluramine suppresses the increased calorie and carbohydrate intakes and improves the mood of women with premenstrual depression. Obstet Gynecol. 1990 Aug; 76(2):296-301.
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Conlay LA, Maher TJ, Wurtman RJ. Alanine increases blood pressure during hypotension. Pharmacol Toxicol. 1990 May; 66(5):415-6.
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Buyukuysal RL, Wurtman RJ. 4-Aminopyridine increases acetylcholine release without diminishing membrane phosphatidylcholine. J Neurochem. 1990 Apr; 54(4):1302-9.
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Sturner WQ, Lynch HJ, Deng MH, Gleason RE, Wurtman RJ. Melatonin concentrations in the sudden infant death syndrome. Forensic Sci Int. 1990 Mar; 45(1-2):171-80.
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Sandmann J, Wurtman RJ. Phospholipase D and phospholipase C in human cholinergic neuroblastoma (LA-N-2) cells: modulation by muscarinic agonists and protein kinase C. Adv Second Messenger Phosphoprotein Res. 1990; 24:176-81.
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Wurtman RJ, Blusztajn JK, Ulus IH, Coviella IL, Buyukuysal RL, Growdon JH, Slack BE. Choline metabolism in cholinergic neurons: implications for the pathogenesis of neurodegenerative diseases. Adv Neurol. 1990; 51:117-25.
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Acworth IN, Ressler K, Wurtman RJ. Feeding-associated alterations in striatal neurotransmitter release. Ann N Y Acad Sci. 1989 Dec 18; 575:596-8.
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Laferrere B, Wurtman RJ. Effect of D-fenfluramine on serotonin release in brains of anaesthetized rats. Brain Res. 1989 Dec 18; 504(2):258-63.
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Schaechter JD, Wurtman RJ. Tryptophan availability modulates serotonin release from rat hypothalamic slices. J Neurochem. 1989 Dec; 53(6):1925-33.
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Wurtman JJ, Brzezinski A, Wurtman RJ, Laferrere B. Effect of nutrient intake on premenstrual depression. Am J Obstet Gynecol. 1989 Nov; 161(5):1228-34.
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O'Rourke D, Wurtman JJ, Wurtman RJ, Chebli R, Gleason R. Treatment of seasonal depression with d-fenfluramine. J Clin Psychiatry. 1989 Sep; 50(9):343-7.
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Slack BE, Liscovitch M, Blusztajn JK, Wurtman RJ. Uptake of exogenous phosphatidylserine by human neuroblastoma cells stimulates the incorporation of [methyl-14C]choline into phosphatidylcholine. J Neurochem. 1989 Aug; 53(2):472-81.
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During MJ, Acworth IN, Wurtman RJ. Dopamine release in rat striatum: physiological coupling to tyrosine supply. J Neurochem. 1989 May; 52(5):1449-54.
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Ulus IH, Wurtman RJ, Mauron C, Blusztajn JK. Choline increases acetylcholine release and protects against the stimulation-induced decrease in phosphatide levels within membranes of rat corpus striatum. Brain Res. 1989 Apr 10; 484(1-2):217-27.
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Buyukuysal RL, Wurtman RJ. Tetrahydroaminoacridine but not 4-aminopyridine inhibits high-affinity choline uptake in striatal and hippocampal synaptosomes. Brain Res. 1989 Mar 20; 482(2):371-5.
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Conlay LA, Wurtman RJ, Lopez G-Coviella I, Blusztajn JK, Vacanti CA, Logue M, During M, Caballero B, Maher TJ, Evoniuk G. Effects of running the Boston marathon on plasma concentrations of large neutral amino acids. J Neural Transm. 1989; 76(1):65-71.
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Schaechter JD, Wurtman RJ. Effect of chronic D-fenfluramine administration on rat hypothalamic serotonin levels and release. Life Sci. 1989; 44(4):265-71.
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Wurtman RJ, Wurtman JJ. Carbohydrates and depression. Sci Am. 1989 Jan; 260(1):68-75.
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Wurtman RJ, O'Rourke D, Wurtman JJ. Nutrient imbalances in depressive disorders. Possible brain mechanisms. Ann N Y Acad Sci. 1989; 575:75-82; discussion 82-5.
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Lehnert H, Beyer J, Reinstein DK, Richardson UI, Wurtman RJ. Relationship between pituitary ACTH content and hypothalamic catecholamines in the rat. Res Exp Med (Berl). 1989; 189(4):289-93.
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Wurtman R, Caballero B, Salzman E. Facilitation of levodopa-induced dyskinesias by dietary carbohydrates. N Engl J Med. 1988 Nov 10; 319(19):1288-9.
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During MJ, Acworth IN, Wurtman RJ. Phenylalanine administration influences dopamine release in the rat's corpus striatum. Neurosci Lett. 1988 Oct 31; 93(1):91-5.
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Acworth IN, During MJ, Wurtman RJ. Tyrosine: effects on catecholamine release. Brain Res Bull. 1988 Sep; 21(3):473-7.
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Caballero B, Finer N, Wurtman RJ. Plasma amino acids and insulin levels in obesity: response to carbohydrate intake and tryptophan supplements. Metabolism. 1988 Jul; 37(7):672-6.
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During MJ, Acworth IN, Wurtman RJ. Effects of systemic L-tyrosine on dopamine release from rat corpus striatum and nucleus accumbens. Brain Res. 1988 Jun 14; 452(1-2):378-80.
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Godley BF, Wurtman RJ. Release of endogenous dopamine from the superfused rabbit retina in vitro: effect of light stimulation. Brain Res. 1988 Jun 14; 452(1-2):393-5.
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Conlay LA, Evoniuk G, Wurtman RJ. Endogenous adenosine and hemorrhagic shock: effects of caffeine administration or caffeine withdrawal. Proc Natl Acad Sci U S A. 1988 Jun; 85(12):4483-5.
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Brzezinski A, Lynch HJ, Seibel MM, Deng MH, Nader TM, Wurtman RJ. The circadian rhythm of plasma melatonin during the normal menstrual cycle and in amenorrheic women. J Clin Endocrinol Metab. 1988 May; 66(5):891-5.
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Brzezinski A, Wurtman RJ. The pineal gland: its possible roles in human reproduction. Obstet Gynecol Surv. 1988 Apr; 43(4):197-207.
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Ulus IH, Wurtman RJ. Prevention by choline of the depletion of membrane phosphatidylcholine by a cholinesterase inhibitor. N Engl J Med. 1988 Jan 21; 318(3):191.
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Wurtman RJ. Effects of dietary amino acids, carbohydrates, and choline on neurotransmitter synthesis. Mt Sinai J Med. 1988 Jan; 55(1):75-86.
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Wurtman RJ. Neurotransmitters, control of appetite, and obesity. Curr Concepts Nutr. 1988; 16:27-34.
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Kaye WH, Gwirtsman HE, Brewerton TD, George DT, Wurtman RJ. Bingeing behavior and plasma amino acids: a possible involvement of brain serotonin in bulimia nervosa. Psychiatry Res. 1988 Jan; 23(1):31-43.
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Wurtman RJ. Effects of their nutrient precursors on the synthesis and release of serotonin, the catecholamines, and acetylcholine: implications for behavioral disorders. Clin Neuropharmacol. 1988; 11 Suppl 1:S187-93.
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Kim SH, Wurtman RJ. Selective effects of CGS 10686B, dl-fenfluramine or fluoxetine on nutrient selection. Physiol Behav. 1988; 42(4):319-22.
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Conlay LA, Maher TJ, Roberts CH, Wurtman RJ. Effects of hemorrhagic hypotension on tyrosine concentrations in rat spinal cord and plasma. Neurochem Int. 1988; 12(3):291-5.
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Holbrook PG, Wurtman RJ. Presence of base-exchange activity in rat brain nerve endings: dependence on soluble substrate concentrations and effect of cations. J Neurochem. 1988 Jan; 50(1):156-62.
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Wurtman RJ, Wurtman JJ. Do carbohydrates affect food intake via neurotransmitter activity? Appetite. 1988; 11 Suppl 1:42-7.
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Liscovitch M, Slack B, Blusztajn JK, Wurtman RJ. Differential regulation of phosphatidylcholine biosynthesis by 12-O-tetradecanoylphorbol-13-acetate and diacylglycerol in NG108-15 neuroblastoma x glioma hybrid cells. J Biol Chem. 1987 Dec 25; 262(36):17487-91.
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Wurtman RJ. Nutrients affecting brain composition and behavior. Integr Psychiatry. 1987 Dec; 5(4):226-38; discussion 238-57.
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Maher TJ, Wurtman RJ. Possible neurologic effects of aspartame, a widely used food additive. Environ Health Perspect. 1987 Nov; 75:53-7.
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Milner JD, Reinstein DK, Wurtman RJ. Dopamine synthesis in rat striatum: mobilization of tyrosine from non-dopaminergic cells. Experientia. 1987 Oct 15; 43(10):1109-10.
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Irie K, Wurtman RJ. Release of norepinephrine from rat hypothalamic slices: effects of desipramine and tyrosine. Brain Res. 1987 Oct 13; 423(1-2):391-4.
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Lieberman HR, Wurtman RJ, Emde GG, Coviella IL. The effects of caffeine and aspirin on mood and performance. J Clin Psychopharmacol. 1987 Oct; 7(5):315-20.
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Lehnert H, Lombardi F, Raeder EA, Lorenzo AV, Verrier RL, Lown B, Wurtman RJ. Increased release of brain serotonin reduces vulnerability to ventricular fibrillation in the cat. J Cardiovasc Pharmacol. 1987 Oct; 10(4):389-97.
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Lakher M, Wurtman RJ. In vivo synthesis of phosphatidylcholine in rat brain via the phospholipid methylation pathway. Brain Res. 1987 Sep 1; 419(1-2):131-40.
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Evoniuk G, Jacobson KA, Shamim MT, Daly JW, Wurtman RJ. A1- and A2-selective adenosine antagonists: in vivo characterization of cardiovascular effects. J Pharmacol Exp Ther. 1987 Sep; 242(3):882-7.
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Waldhauser F, Lieberman HR, Lynch HJ, Waldhauser M, Herkner K, Frisch H, Vierhapper H, Waldhäusl W, Schemper M, Wurtman RJ, et al. A pharmacological dose of melatonin increases PRL levels in males without altering those of GH, LH, FSH, TSH, testosterone or cortisol. Neuroendocrinology. 1987 Aug; 46(2):125-30.
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Brzezinski A, Lynch HJ, Wurtman RJ, Seibel MM. Possible contribution of melatonin to the timing of the luteinizing hormone surge. N Engl J Med. 1987 Jun 11; 316(24):1550-1.
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Lakher MB, Wurtman RJ. Molecular composition of the phosphatidylcholines produced by the phospholipid methylation pathway in rat brain in vivo. Biochem J. 1987 Jun 1; 244(2):325-30.
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Brzezinski A, Seibel MM, Lynch HJ, Deng MH, Wurtman RJ. Melatonin in human preovulatory follicular fluid. J Clin Endocrinol Metab. 1987 Apr; 64(4):865-7.
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Wurtman RJ. Aspartame effects on brain serotonin. Am J Clin Nutr. 1987 Apr; 45(4):799-803.
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Ulus IH, Wurtman RJ. Choline increases acetylcholine release. Lancet. 1987 Mar 14; 1(8533):624.
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Evoniuk G, von Borstel RW, Wurtman RJ. Antagonism of the cardiovascular effects of adenosine by caffeine or 8-(p-sulfophenyl)theophylline. J Pharmacol Exp Ther. 1987 Feb; 240(2):428-32.
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Lopez G-Coviella I, Agut J, Von Borstel R, Wurtman RJ. Metabolism of cytidine (5?)-diphosphocholine (cdp-choline) following oral and intravenous administration to the human and the rat. Neurochem Int. 1987; 11(3):293-7.
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Blusztajn JK, Liscovitch M, Mauron C, Richardson UI, Wurtman RJ. Phosphatidylcholine as a precursor of choline for acetylcholine synthesis. J Neural Transm Suppl. 1987; 24:247-59.
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Wurtman RJ. Dietary treatments that affect brain neurotransmitters. Effects on calorie and nutrient intake. Ann N Y Acad Sci. 1987; 499:179-90.
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Hilibrand AS, Ingrid Richardson U, Blusztajn JK, Wurtman RJ. NG108-15 hybrid cells take up but do not synthesize serotonin. Neurochem Int. 1987; 10(2):185-9.
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Milner JD, Wurtman RJ. Tyrosine availability: a presynaptic factor controlling catecholamine release. Adv Exp Med Biol. 1987; 221:211-21.
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Liscovitch M, Blusztajn JK, Freese A, Wurtman RJ. Stimulation of choline release from NG108-15 cells by 12-O-tetradecanoylphorbol 13-acetate. Biochem J. 1987 Jan 1; 241(1):81-6.
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Lieberman HR, Wurtman RJ, Emde GG, Roberts C, Coviella IL. The effects of low doses of caffeine on human performance and mood. Psychopharmacology (Berl). 1987; 92(3):308-12.
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Wurtman RJ, Maher TJ. Effects of oral aspartame on plasma phenylalanine in humans and experimental rodents. Short note. J Neural Transm. 1987; 70(1-2):169-73.
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Liscovitch M, Freese A, Blusztajn JK, Wurtman RJ. Phosphatidylcholine biosynthesis in the neuroblastoma-glioma hybrid cell line NG108-15: stimulation by phorbol esters. J Neurochem. 1986 Dec; 47(6):1936-41.
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Milner JD, Irie K, Wurtman RJ. Effects of phenylalanine on the release of endogenous dopamine from rat striatal slices. J Neurochem. 1986 Nov; 47(5):1444-8.
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Conlay LA, Wurtman RJ, Blusztajn K, Coviella IL, Maher TJ, Evoniuk GE. Decreased plasma choline concentrations in marathon runners. N Engl J Med. 1986 Oct 2; 315(14):892.
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Caballero B, Mahon BE, Rohr FJ, Levy HL, Wurtman RJ. Plasma amino acid levels after single-dose aspartame consumption in phenylketonuria, mild hyperphenylalaninemia, and heterozygous state for phenylketonuria. J Pediatr. 1986 Oct; 109(4):668-71.
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Yokogoshi H, Wurtman RJ. Meal composition and plasma amino acid ratios: effect of various proteins or carbohydrates, and of various protein concentrations. Metabolism. 1986 Sep; 35(9):837-42.
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Conlay LA, Maher TJ, Godley BF, Wurtman RJ. Spinal cord noradrenergic neurons are activated in hypotension. Brain Res. 1986 Jun 4; 375(1):210-3.
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Wurtman RJ. Ways that foods can affect the brain. Nutr Rev. 1986 May; 44 Suppl:2-6.
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Milner JD, Wurtman RJ. Catecholamine synthesis: physiological coupling to precursor supply. Biochem Pharmacol. 1986 Mar 15; 35(6):875-81.
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Yokogoshi H, Wurtman RJ. Acute effects of oral or parenteral aspartame on catecholamine metabolism in various regions of rat brain. J Nutr. 1986 Mar; 116(3):356-64.
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Huff FJ, Maire JC, Growdon JH, Corkin S, Wurtman RJ. Cholinesterases in cerebrospinal fluid. Correlations with clinical measures in Alzheimer's disease. J Neurol Sci. 1986 Feb; 72(2-3):121-9.
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Evoniuk GE, von Borstel RW, Wurtman RJ. Adenosine affects sympathetic neurotransmission at multiple sites in vivo. J Pharmacol Exp Ther. 1986 Feb; 236(2):350-5.
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von Borstel RW, Evoniuk GE, Wurtman RJ. Adenosine potentiates sympathomimetic effects of nicotinic agonists in vivo. J Pharmacol Exp Ther. 1986 Feb; 236(2):344-9.
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Lieberman HR, Wurtman RJ. Foods and food constituents that affect the brain and human behavior. Food Technol. 1986 Jan; 40(1):139-41.
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Lopez I, Coviella G, Agut J, Wurtman RJ. Effect of cytidine(5')diphosphocholine (CDP-choline) on the total urinary excretion of 3-methoxy-4-hydroxyphenylglycol (MHPG) by rats and humans. J Neural Transm. 1986; 66(2):129-34.
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Wurtman RJ, Wurtman JJ. Carbohydrate craving, obesity and brain serotonin. Appetite. 1986; 7 Suppl:99-103.
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Tacconi MT, Wurtman RJ. Piracetam: physiological disposition and mechanism of action. Adv Neurol. 1986; 43:675-85.
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Wurtman RJ. Strategies in the development of drugs that might be useful in cognitive disorders. Clin Neuropharmacol. 1986; 9 Suppl 3:S3-7.
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Blusztajn JK, Holbrook PG, Lakher M, Liscovitch M, Maire JC, Mauron C, Richardson UI, Tacconi M, Wurtman RJ. "Autocannibalism" of membrane choline-phospholipids: physiology and pathology. Psychopharmacol Bull. 1986; 22(3):781-6.
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Wurtman RJ. Melatonin in humans. J Neural Transm Suppl. 1986; 21:1-8.
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Yokogoshi H, Theall CL, Wurtman RJ. Selection of dietary protein and carbohydrate by rats: changes with maturation. Physiol Behav. 1986; 36(5):979-82.
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Reinstein DK, Lehnert H, Wurtman RJ. Dietary tyrosine suppresses the rise in plasma corticosterone following acute stress in rats. Life Sci. 1985 Dec 9; 37(23):2157-63.
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Blusztajn JK, Zeisel SH, Wurtman RJ. Developmental changes in the activity of phosphatidylethanolamine N-methyltransferases in rat brain. Biochem J. 1985 Dec 1; 232(2):505-11.
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Liscovitch M, Freese A, Blusztajn JK, Wurtman RJ. High-performance liquid chromatography of water-soluble choline metabolites. Anal Biochem. 1985 Nov 15; 151(1):182-7.
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Wurtman RJ. Aspartame: possible effect on seizure susceptibility. Lancet. 1985 Nov 9; 2(8463):1060.
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Wurtman RJ. Melatonin as a hormone in humans: a history. Yale J Biol Med. 1985 Nov-Dec; 58(6):547-52.
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Tacconi M, Wurtman RJ. Rat brain phosphatidyl-N,N-dimethylethanolamine is rich in polyunsaturated fatty acids. J Neurochem. 1985 Sep; 45(3):805-9.
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Small DH, Wurtman RJ. Association of serotonin, dopamine, or noradrenaline with an actin-like component in pheochromocytoma (PC12) cells. J Neurochem. 1985 Sep; 45(3):825-31.
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Small DH, Wurtman RJ. Binding of [3H]serotonin to skeletal muscle actin. J Neurochem. 1985 Sep; 45(3):819-24.
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Milner JD, Wurtman RJ. Tyrosine availability determines stimulus-evoked dopamine release from rat striatal slices. Neurosci Lett. 1985 Aug 30; 59(2):215-20.
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Logue MP, Growdon JH, Coviella IL, Wurtman RJ. Differential effects of DSP-4 administration on regional brain norepinephrine turnover in rats. Life Sci. 1985 Aug 5; 37(5):403-9.
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Lieberman HR, Corkin S, Spring BJ, Wurtman RJ, Growdon JH. The effects of dietary neurotransmitter precursors on human behavior. Am J Clin Nutr. 1985 Aug; 42(2):366-70.
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Tacconi M, Wurtman RJ. Phosphatidylcholine produced in rat synaptosomes by N-methylation is enriched in polyunsaturated fatty acids. Proc Natl Acad Sci U S A. 1985 Jul; 82(14):4828-31.
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Conlay LA, Maher TJ, Wurtman RJ. Tyrosine accelerates catecholamine synthesis in hemorrhaged hypotensive rats. Brain Res. 1985 Apr 29; 333(1):81-4.
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Wurtman RJ, Lieberman HR. Melatonin secretion as a mediator of circadian variations in sleep and sleepiness. J Pineal Res. 1985; 2(3):301-3.
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Maire JC, Wurtman RJ. Effects of electrical stimulation and choline availability on the release and contents of acetylcholine and choline in superfused slices from rat striatum. J Physiol (Paris). 1985; 80(3):189-95.
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Wurtman J, Wurtman R, Mark S, Tsay R, Gilbert W, Growdon J. d-Fenfluramine selectively suppresses carbohydrate snacking by obese subjects. Int J Eat Disord. 1985; 4(1):89-99.
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Agharanya JC, Wurtman RJ. Effect of dietary proteins and carbohydrates on urinary and sympathoadrenal catecholamines. Neurochem Int. 1985; 7(2):271-7.
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Lynch HJ, Deng MH, Wurtman RJ. Indirect effects of light: ecological and ethological considerations. Ann N Y Acad Sci. 1985; 453:231-41.
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Wurtman RJ. Alzheimer's disease. Sci Am. 1985 Jan; 252(1):62-6, 71-4.
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Lieberman HR, Garfield G, Waldhauser F, Lynch HJ, Wurtman RJ. Possible behavioral consequences of light-induced changes in melatonin availability. Ann N Y Acad Sci. 1985; 453:242-52.
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Wurtman RJ, Blusztajn JK, Maire JC. "Autocannibalism" of choline-containing membrane phospholipids in the pathogenesis of Alzheimer's disease-A hypothesis. Neurochem Int. 1985; 7(2):369-72.
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Lieberman HR, Waldhauser F, Garfield G, Lynch HJ, Wurtman RJ. Effects of melatonin on human mood and performance. Brain Res. 1984 Dec 10; 323(2):201-7.
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Agut J, Coviella IL, Wurtman RJ. Cytidine(5')diphosphocholine enhances the ability of haloperidol to increase dopamine metabolites in the striatum of the rat and to diminish stereotyped behavior induced by apomorphine. Neuropharmacology. 1984 Dec; 23(12A):1403-6.
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Waldhauser F, Waldhauser M, Lieberman HR, Deng MH, Lynch HJ, Wurtman RJ. Bioavailability of oral melatonin in humans. Neuroendocrinology. 1984 Oct; 39(4):307-13.
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Tacconi MT, Wurtman RJ. Physiological disposition of oral piracetam in Sprague-Dawley rats. J Pharm Pharmacol. 1984 Oct; 36(10):659-62.
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Moses PL, Wurtman RJ. The ability of certain anorexic drugs to suppress food consumption depends on the nutrient composition of the test diet. Life Sci. 1984 Sep 17; 35(12):1297-300.
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Conlay LA, Maher TJ, Wurtman RJ. Tyrosine's pressor effect in hypotensive rats is not mediated by tyramine. Life Sci. 1984 Sep 10; 35(11):1207-12.
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von Borstel RW, Renshaw AA, Wurtman RJ. Adenosine strongly potentiates pressor responses to nicotine in rats. Proc Natl Acad Sci U S A. 1984 Sep; 81(17):5599-603.
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Spindel ER, Wurtman RJ, McCall A, Carr DB, Conlay L, Griffith L, Arnold MA. Neuroendocrine effects of caffeine in normal subjects. Clin Pharmacol Ther. 1984 Sep; 36(3):402-7.
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Lynch HJ, Deng MH, Wurtman RJ. Light intensities required to suppress nocturnal melatonin secretion in albino and pigmented rats. Life Sci. 1984 Aug 20; 35(8):841-7.
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Yokogoshi H, Roberts CH, Caballero B, Wurtman RJ. Effects of aspartame and glucose administration on brain and plasma levels of large neutral amino acids and brain 5-hydroxyindoles. Am J Clin Nutr. 1984 Jul; 40(1):1-7.
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Lehnert H, Reinstein DK, Strowbridge BW, Wurtman RJ. Neurochemical and behavioral consequences of acute, uncontrollable stress: effects of dietary tyrosine. Brain Res. 1984 Jun 15; 303(2):215-23.
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Reinstein DK, Lehnert H, Scott NA, Wurtman RJ. Tyrosine prevents behavioral and neurochemical correlates of an acute stress in rats. Life Sci. 1984 Jun 4; 34(23):2225-31.
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Wurtman RJ, Maher TJ. Strategies for assessing the effects of food additives on the brain and behavior. Fundam Appl Toxicol. 1984 Jun; 4(3 Pt 2):S318-22.
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Milner JD, Wurtman RJ. Release of endogenous dopamine from electrically stimulated slices of rat striatum. Brain Res. 1984 May 28; 301(1):139-42.
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Maher TJ, Glaeser BS, Wurtman RJ. Diurnal variations in plasma concentrations of basic and neutral amino acids and in red cell concentrations of aspartate and glutamate: effects of dietary protein intake. Am J Clin Nutr. 1984 May; 39(5):722-9.
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Theall CL, Wurtman JJ, Wurtman RJ. Self-selection and regulation of protein: carbohydrate ratio in foods adult rats eat. J Nutr. 1984 Apr; 114(4):711-8.
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Waldhauser F, Weiszenbacher G, Frisch H, Zeitlhuber U, Waldhauser M, Wurtman RJ. Fall in nocturnal serum melatonin during prepuberty and pubescence. Lancet. 1984 Feb 18; 1(8373):362-5.
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Small DH, Wurtman RJ. Serotonin binds specifically and saturably to an actin-like protein isolated from rat brain synaptosomes. Proc Natl Acad Sci U S A. 1984 Feb; 81(3):959-63.
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Dews P, Grice HC, Neims A, Wilson J, Wurtman R. Report of Fourth International Caffeine Workshop, Athens, 1982. Food Chem Toxicol. 1984 Feb; 22(2):163-9.
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Maire JC, Wurtman RJ. Choline production from choline-containing phospholipids: a hypothetical role in Alzheimer's disease and aging. Prog Neuropsychopharmacol Biol Psychiatry. 1984; 8(4-6):637-42.
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Wurtman RJ, Wurtman JJ. Nutrients, neurotransmitter synthesis, and the control of food intake. Res Publ Assoc Res Nerv Ment Dis. 1984; 62:77-86.
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Wurtman JJ, Wurtman RJ. d-Fenfluramine selectively decreases carbohydrate but not protein intake in obese subjects. Int J Obes. 1984; 8 Suppl 1:79-84.
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Wurtman RJ. Effects of foods and nutrients on brain neurotransmitters. Curr Concepts Nutr. 1984; 13:103-12.
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Lieberman HR, Corkin S, Spring BJ, Garfield GS, Growdon JH, Wurtman RJ. The effects of tryptophan and tyrosine on human mood and performance. Psychopharmacol Bull. 1984; 20(3):595-8.
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Maher TJ, Wurtman RJ. High doses of aspartame reduce blood pressure in spontaneously hypertensive rats. N Engl J Med. 1983 Nov 3; 309(18):1125.
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Wurtman RJ. Stimulation of catecholamine secretion by choline. Science. 1983 Oct 14; 222(4620):188.
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Glaeser BS, Maher TJ, Wurtman RJ. Changes in brain levels of acidic, basic, and neutral amino acids after consumption of single meals containing various proportions of protein. J Neurochem. 1983 Oct; 41(4):1016-21.
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Wurtman RJ. Neurochemical changes following high-dose aspartame with dietary carbohydrates. N Engl J Med. 1983 Aug 18; 309(7):429-30.
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Blusztajn JK, Wurtman RJ. Choline and cholinergic neurons. Science. 1983 Aug 12; 221(4611):614-20.
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Rivest RW, Wurtman RJ. Relationship between light intensity and the melatonin and drinking rhythms of rats. Neuroendocrinology. 1983 Aug; 37(2):155-60.
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Wurtman RJ. Behavioural effects of nutrients. Lancet. 1983 May 21; 1(8334):1145-7.
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Spindel E, Griffith L, Wurtman RJ. Neuroendocrine effects of caffeine. II. Effects on thyrotropin and corticosterone secretion. J Pharmacol Exp Ther. 1983 May; 225(2):346-50.
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Leprohon CE, Blusztajn JK, Wurtman RJ. Dopamine stimulation of phosphatidylcholine (lecithin) biosynthesis in rat brain neurons. Proc Natl Acad Sci U S A. 1983 Apr; 80(7):2063-6.
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Reinstein DK, DeBoissiere T, Robinson N, Wurtman RJ. Radial maze performance in three strains of mice: role of the fimbria/fornix. Brain Res. 1983 Mar 14; 263(1):172-6.
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von Borstel RW, Wurtman RJ, Conlay LA. Chronic caffeine consumption potentiates the hypotensive action of circulating adenosine. Life Sci. 1983 Mar 7; 32(10):1151-8.
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Wurtman JJ, Moses PL, Wurtman RJ. Prior carbohydrate consumption affects the amount of carbohydrate that rats choose to eat. J Nutr. 1983 Jan; 113(1):70-8.
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Wurtman RJ. Food consumption, neurotransmitter synthesis, and human behaviour. Experientia Suppl. 1983; 44:356-69.
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Gibson CJ, Watkins CJ, Wurtman RJ. Tyrosine administration enhances dopamine synthesis and release in light-activated rat retina. J Neural Transm. 1983; 56(2-3):153-60.
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Heraief E, Burckhardt P, Mauron C, Wurtman JJ, Wurtman RJ. The treatment of obesity by carbohydrate deprivation suppresses plasma tryptophan and its ratio to other large neutral amino acids. J Neural Transm. 1983; 57(3):187-95.
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Conlay LA, Maher TJ, Moses PL, Wurtman RJ. Tyrosine's vasoactive effect in the dog shock model depends on the animal's starting blood pressure. J Neural Transm. 1983; 58(1-2):69-74.
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McCall AL, Millington WR, Wurtman RJ. Blood-brain barrier transport of caffeine: dose-related restriction of adenine transport. Life Sci. 1982 Dec 13; 31(24):2709-15.
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Agharanya JC, Wurtman RJ. Studies on the mechanism by which tyrosine raises urinary catecholamines. Biochem Pharmacol. 1982 Nov 15; 31(22):3577-80.
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McCall AL, Millington WR, Wurtman RJ. Metabolic fuel and amino acid transport into the brain in experimental diabetes mellitus. Proc Natl Acad Sci U S A. 1982 Sep; 79(17):5406-10.
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Botticelli LJ, Wurtman RJ. Septohippocampal cholinergic neurons are regulated trans-synaptically by endorphin and corticotropin neuropeptides. J Neurosci. 1982 Sep; 2(9):1316-21.
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Pan RM, Mauron C, Glaeser B, Wurtman RJ. Effect of various oral glucose doses on plasma neutral amino acid levels. Metabolism. 1982 Sep; 31(9):937-43.
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Alonso R, Gibson CJ, Wurtman RJ, Agharanya JC, Prieto L. Elevation of urinary catecholamines and their metabolites following tyrosine administration in humans. Biol Psychiatry. 1982 Jul; 17(7):781-90.
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Millington WR, Wurtman RJ. Choline and physostigmine enhance haloperidol-induced HVA and DOPAC accumulation. Eur J Pharmacol. 1982 Jun 4; 80(4):431-4.
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Millington WR, Wurtman RJ. Choline administration elevates brain phosphorylcholine concentrations. J Neurochem. 1982 Jun; 38(6):1748-52.
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Wurtman RJ. Nutrients that modify brain function. Sci Am. 1982 Apr; 246(4):50-9.
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Growdon JH, Melamed E, Logue M, Hefti F, Wurtman RJ. Effects of oral L-tyrosine administration on CSF tyrosine and homovanillic acid levels in patients with Parkinson's disease. Life Sci. 1982 Mar 8; 30(10):827-32.
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Agharanya JC, Wurtman RJ. Effect of acute administration of large neutral and other amino acids on urinary excretion of catecholamines1,2. Life Sci. 1982 Mar 1; 30(9):739-46.
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Zeisel SH, Stanbury JB, Wurtman RJ, Brigida M, Fierro-Benitez R. Choline content of mothers' milk in Ecuador and Boston. N Engl J Med. 1982 Jan 21; 306(3):175-6.
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Melamed E, Hefti F, Wurtman RJ. Compensatory mechanisms in the nigrostriatal dopaminergic system in Parkinson's disease: studies in an animal model. Isr J Med Sci. 1982 Jan; 18(1):159-63.
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Gelenberg AJ, Wojcik JD, Gibson CJ, Wurtman RJ. Tyrosine for depression. J Psychiatr Res. 1982-1983; 17(2):175-80.
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Lynch HJ, Wurtman RJ, Ronsheim P. Activity and melatonin rhythms among rats with recourse to dark burrows. Prog Clin Biol Res. 1982; 92:75-86.
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Hirsch JA, Goldberg S, Wurtman RJ. Effect of (+)- or (-)-enantiomers of fenfluramine or norfenfluramine on nutrient selection by rats. J Pharm Pharmacol. 1982 Jan; 34(1):18-21.
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Oishi T, Wurtman RJ. Effect of tyrosine on brain catecholamine turnover in reserpine-treated rats. J Neural Transm. 1982; 53(2-3):101-8.
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Lieberman HR, Corkin S, Spring BJ, Growdon JH, Wurtman RJ. Mood, performance, and pain sensitivity: changes induced by food constituents. J Psychiatr Res. 1982-1983; 17(2):135-45.
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Wurtman RJ. Research strategies for assessing the behavioral effects of food and nutrients. Introduction. J Psychiatr Res. 1982-1983; 17(2):103-5.
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Gibson CJ, Watkins CJ, Wurtman RJ. The effects of tyrosine and other nutrients on neurotransmitter synthesis in the brain and retina. Retina. 1982; 2(4):332-40.
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Wurtman JJ, Wurtman RJ. Studies on the appetite for carbohydrates in rats and humans. J Psychiatr Res. 1982-1983; 17(2):213-21.
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Martin-Du Pan RC, Wurtman RJ. [The role of nutrition in the synthesis of neurotransmitters and in cerebral functions: clinical implications]. Schweiz Med Wochenschr. 1981 Sep 26; 111(39):1422-34.
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Zeisel SH, Wurtman RJ. Developmental changes in rat blood choline concentration. Biochem J. 1981 Sep 15; 198(3):565-70.
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Zeisel S, Reinstein D, Corkin S, Growdon J, Wurtman R. Cholinergic neurones and memory. Nature. 1981 Sep 17-23; 293(5829):187-8.
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Lynch HJ, Rivest RW, Ronsheim PM, Wurtman RJ. Light intensity and the control of melatonin secretion in rats. Neuroendocrinology. 1981 Sep; 33(3):181-5.
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Chiel HJ, Wurtman RJ. Short-term variations in diet composition change the pattern of spontaneous motor activity in rats. Science. 1981 Aug 7; 213(4508):676-8.
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Spindel ER, Pettibone DJ, Wurtman RJ. Thyrotropin-releasing hormone (TRH) content of rat striatum: modification by drugs and lesions. Brain Res. 1981 Jul 20; 216(2):323-31.
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Spindel ER, Lakher M, Wurtman RJ. Formation and degradation of deamido-TRH (pyroglutamyl-histidyl-proline) in rat brain after intraventricular injection of TRH. Brain Res. 1981 Jul 20; 216(2):343-50.
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Zeisel SH, Mauron C, Watkins CJ, Wurtman RJ. Developmental changes in brain indoles, serum tryptophan and other serum neutral amino acids in the rat. Brain Res. 1981 Jul; 227(4):551-64.
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Torii K, Takasaki Y, Iwata S, Wurtman RJ. Changes in blood osmolarity electrolytes, and metabolites among adult rats treated with a neurotoxic dose of MSG. Life Sci. 1981 Jun 22; 28(25):2855-64.
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Melamed E, Hefti F, Pettibone DJ, Liebman J, Wurtman RJ. Aromatic L-amino acid decarboxylase in rat corpus striatum: implications for action of L-dopa in parkinsonism. Neurology. 1981 Jun; 31(6):651-5.
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Conlay LA, Maher TJ, Wurtman RJ. Tyrosine increases blood pressure in hypotensive rats. Science. 1981 May 1; 212(4494):559-60.
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Botticelli LJ, Wurtman RJ. Choline reverses naloxone-induced decreases in hippocampal acetylcholine content and suppresses escape behavior in opiate-dependent rats. Brain Res. 1981 Apr 6; 210(1-2):479-84.
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Blusztajn JK, Wurtman RJ. Choline biosynthesis by a preparation enriched in synaptosomes from rat brain. Nature. 1981 Apr 2; 290(5805):417-8.
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Hefti F, Melamed E, Wurtman RJ. The site of dopamine formation in rat striatum after L-dopa administration. J Pharmacol Exp Ther. 1981 Apr; 217(1):189-97.
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Spindel E, Pettibone D, Fisher L, Fernstrom J, Wurtman R. Characterization of neuropeptides by reversed-phase, ion-pair liquid chromatography with post-column detection by radioimmunoassay. Application to thyrotropin-releasing hormone, substance P, and vasopressin. J Chromatogr. 1981 Mar 13; 222(3):381-7.
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Wurtman RJ, Magil SG, Reinstein DK. Piracetam diminishes hippocampal acetylcholine levels in rats. Life Sci. 1981 Mar 9; 28(10):1091-3.
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Scott NA, DeSilva RA, Lown B, Wurtman RJ. Tyrosine administration decreases vulnerability to ventricular fibrillation in the normal canine heart. Science. 1981 Feb 13; 211(4483):727-9.
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Morre MC, Wurtman RJ. Characteristics of synaptosomal tyrosine uptake in various brain regions: effect of other amino acids. Life Sci. 1981 Jan 5; 28(1):65-75.
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Wurtman RJ. The effects of nutritional factors on memory. Acta Neurol Scand Suppl. 1981; 89:145-54.
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Magil SG, Zeisel SH, Wurtman RJ. Effects of ingesting soy or egg lecithins on serum choline, brain choline and brain acetylcholine. J Nutr. 1981 Jan; 111(1):166-70.
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Botticelli LJ, Wurtman RJ. Corticotropin regulates transsynaptically the activity of septo-hippocampal cholinergic neurones. Nature. 1981 Jan 1; 289(5793):75-6.
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Agharanya JC, Alonso R, Wurtman RJ. Changes in catecholamine excretion after short-term tyrosine ingestion in normally fed human subjects. Am J Clin Nutr. 1981 Jan; 34(1):82-7.
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Melamed E, Hefti F, Wurtman RJ. Nonaminergic striatal neurons convert exogenous L-dopa to dopamine in parkinsonism. Ann Neurol. 1980 Dec; 8(6):558-63.
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Wurtman RJ, Hefti F, Melamed E. Precursor control of neurotransmitter synthesis. Pharmacol Rev. 1980 Dec; 32(4):315-35.
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Spindel ER, Wurtman RJ, Bird ED. Increased TRH content of the basal ganglia in Huntington's disease. N Engl J Med. 1980 Nov 20; 303(21):1235-6.
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Spindel E, Wurtman RJ. TRH immunoreactivity in rat brain regions, spinal cord and pancreas: validation by high-pressure liquid chromatography and thin-layer chromatography. Brain Res. 1980 Nov 17; 201(2):279-88.
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Zeisel SH, Growdon JH, Wurtman RJ, Magil SG, Logue M. Normal plasma choline responses to ingested lecithin. Neurology. 1980 Nov; 30(11):1226-9.
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Pettibone DJ, Wurtman RJ, Leeman SE. Striatal substance P-like immunoreactivity: characterization of high-performance liquid chromatography and aspects of subcellular distribution and in vitro release by potassium. Life Sci. 1980 Oct 27; 27(17):1593-602.
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Gelenberg AJ, Wurtman RJ. L-tyrosine in depression. Lancet. 1980 Oct 18; 2(8199):863-4.
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Melamed E, Hefti F, Wurtman RJ. Decarboxylation of exogenous L-DOPA in rat striatum after lesions of the dopaminergic nigrostriatal neurons: the role of striatal capillaries. Brain Res. 1980 Sep 29; 198(1):244-8.
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Growdon JH, Wurtman RJ. Nutrients and neurotransmitters. N Y State J Med. 1980 Sep; 80(10):1638-9.
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Mauron C, Wurtman JJ, Wurtman RJ. Clonidine increases food and protein consumption in rats. Life Sci. 1980 Sep 1; 27(9):781-91.
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Hefti F, Melamed E, Wurtman RJ. Partial lesions of the dopaminergic nigrostriatal system in rat brain: biochemical characterization. Brain Res. 1980 Aug 11; 195(1):123-37.
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Lynch HJ, Rivest RW, Wurtman RJ. Artificial induction of melatonin rhythms by programmed microinfusion. Neuroendocrinology. 1980 Aug; 31(2):106-11.
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Zeisel SH, Story DL, Wurtman RJ, Brunengraber H. Uptake of free choline by isolated perfused rat liver. Proc Natl Acad Sci U S A. 1980 Aug; 77(8):4417-9.
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Melamed E, Hefti F, Wurtman RJ. Tyrosine administration increases striatal dopamine release in rats with partial nigrostriatal lesions. Proc Natl Acad Sci U S A. 1980 Jul; 77(7):4305-9.
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Spindel E, Arnold M, Cusack B, Wurtman RJ. Effects of caffeine on anterior pituitary and thyroid function in the rat. J Pharmacol Exp Ther. 1980 Jul; 214(1):58-62.
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Alonso R, Ozaki Y, Wurtman RJ. [Daily rhythms of melatonin in pineal, serum and urine of rats (author's transl)]. Reproduccion. 1980 Jul-Sep; 4(3):225-33.
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Wurtman RJ, Urbach F. Risks of artificial tanning. N Engl J Med. 1980 Jun 26; 302(26):1483.
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Melamed E, Hefti F, Wurtman RJ. L-3,4-Dihydroxyphenylalanine and L-5-hydroxytryptophan decarboxylase activities in rat striatum: effect of selective destruction of dopaminergic or serotoninergic input. J Neurochem. 1980 Jun; 34(6):1753-6.
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Zeisel SH, Epstein MF, Wurtman RJ. Elevated choline concentration in neonatal plasma. Life Sci. 1980 May 26; 26(21):1827-31.
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Gelenberg AJ, Wojcik JD, Growdon JH, Sved AF, Wurtman RJ. Tyrosine for the treatment of depression. Am J Psychiatry. 1980 May; 137(5):622-3.
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Maher TJ, Wurtman RJ. L-Threonine administration increases glycine concentrations in the rat central nervous system. Life Sci. 1980 Apr 21; 26(16):1283-6.
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Melamed E, Hefti F, Wurtman RJ. Diminished decarboxylation of L-DOPA in rat striatum after intrastriatal injections of kainic acid. Neuropharmacology. 1980 Apr; 19(4):409-11.
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Pettibone DJ, Wurtman RJ. D-Amphetamine reduces striatal substance P concentrations by presynaptic release of dopamine. Brain Res. 1980 Mar 31; 186(2):409-19.
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Melamed E, Hefti F, Liebman J, Schlosberg AJ, Wurtman RJ. Serotonergic neurones are not involved in action of L-dopa in Parkinson's disease. Nature. 1980 Feb 21; 283(5749):772-4.
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Hefti F, Melamed E, Sahakian BJ, Wurtman RJ. Circling behavior in rats with partial, unilateral nigro-striatal lesions: effect of amphetamine, apomorphine, and DOPA. Pharmacol Biochem Behav. 1980 Feb; 12(2):185-8.
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Hefti F, Melamed E, Wurtman RJ. The decarboxylation of DOPA in the parkinsonian brain: in vivo studies on an animal model. J Neural Transm Suppl. 1980; (16):95-101.
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Melamed E, Glaeser B, Growdon JH, Wurtman RJ. Plasma tyrosine in normal humans: effects of oral tyrosine and protein-containing meals. J Neural Transm. 1980; 47(4):299-306.
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Alonso R, Agharanya JC, Wurtman RJ. Tyrosine loading enhances catecholamine excretion by rats. J Neural Transm. 1980; 49(1-2):31-43.
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Wurtman RJ. The pineal as a neuroendocrine transducer. Hosp Pract. 1980 Jan; 15(1):82-6, 91-2.
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Wurtman RJ. Meeting report: Workshop of the International Study Group (ISG) on the pharmacology of memory disorders associated with aging. J Neural Transm. 1980; 47(4):319-25.
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Zeisel SH, Gelenberg AJ, Growdon JH, Wurtman RJ. Use of choline and lecithin in the treatment of tardive dyskinesia. Adv Biochem Psychopharmacol. 1980; 24:463-70.
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Morre MC, Hefti F, Wurtman RJ. Regional tyrosine levels in rat brain after tyrosine administration. J Neural Transm. 1980; 49(1-2):45-50.
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Blusztajn JK, Zeisel SH, Wurtman RJ. Synthesis of lecithin (phosphatidylcholine) from phosphatidylethanolamine in bovine brain. Brain Res. 1979 Dec 28; 179(2):319-27.
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Zavisca FG, Breau AP, Wurtman RJ. Mechanism of action of methyldopa in the rat. Role of 3-O-methylated metabolites. Circ Res. 1979 Nov; 45(5):684-90.
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Sved AF, Fernstrom JD, Wurtman RJ. Tyrosine administration decreases serum prolactin levels in chronically reserpinized rats. Life Sci. 1979 Oct 8; 25(15):1293-9.
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Fernstrom JD, Wurtman RJ, Hammarstrom-Wiklund B, Rand WM, Munro HN, Davidson CS. Diurnal variations in plasma concentrations of tryptophan, tryosine, and other neutral amino acids: effect of dietary protein intake. Am J Clin Nutr. 1979 Sep; 32(9):1912-22.
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Fernstrom JD, Wurtman RJ, Hammarstrom-Wiklund B, Rand WM, Munro HN, Davidson CS. Diurnal variations in plasma neutral amino acid concentrations among patients with cirrhosis: effect of dietary protein. Am J Clin Nutr. 1979 Sep; 32(9):1923-33.
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Ulus IH, Wurtman RJ. Selective response of rat peripheral sympathetic nervous system to various stimuli. J Physiol. 1979 Aug; 293:513-23.
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Colmenares JL, Wurtman RJ. The relation between urinary 5-hydroxyindoleacetic acid levels and the ratio of tryptophan to other large neutral amino acids placed in the stomach. Metabolism. 1979 Aug; 28(8):820-7.
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Wurtman JJ, Wurtman RJ. Sucrose consumption early in life fails to modify the appetite of adult rats for sweet foods. Science. 1979 Jul 20; 205(4403):321-2.
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Glaeser BS, Melamed E, Growdon JH, Wurtman RJ. Elevation of plasma tyrosine after a single oral dose of L-tyrosine. Life Sci. 1979 Jul 16; 25(3):265-71.
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Spindel E, Wurtman RJ. Reversed-phase, ion-pair separation of thyrotropin-releasing hormone and some analogs. J Chromatogr. 1979 Jul 11; 175(1):198-201.
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Sved AF, Fernstrom JD, Wurtman RJ. Tyrosine administration reduces blood pressure and enhances brain norepinephrine release in spontaneously hypertensive rats. Proc Natl Acad Sci U S A. 1979 Jul; 76(7):3511-4.
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Sahakian BJ, Wurtman RJ, Barr JK, Millington WR, Chiel HJ. Low tryptophan diet decreases brain serotonin and alters response to apomorphine. Nature. 1979 Jun 21; 279(5715):731-2.
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Botticelli LJ, Wurtman RJ. beta-Endorphin administration increases hippocampal acetylcholine levels. Life Sci. 1979 May 7; 24(19):1799-804.
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Growdon JH, Wurtman RJ. Dietary influences on the synthesis of neurotransmitters in the brain. Nutr Rev. 1979 May; 37(5):129-36.
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Watkins CJ, Wiggins JF, Wurtman RJ. Carbidopa elevates hypothalamic dopa and serum prolactin in rats. Life Sci. 1979 Apr 30; 24(18):1675-82.
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Fernstrom MH, Wurtman RJ. Increase in striatal choline acetyltransferase activity after choline administration. Brain Res. 1979 Apr 13; 165(2):358-61.
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Adler J, Lynch HJ, Wurtman RJ. Effect of cyclic changes in environmental lighting and ambient temperature on the daily rhythm in melatonin excretion by rats. Brain Res. 1979 Mar 9; 163(1):111-20.
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Wurtman JJ, Wurtman RJ. Drugs that enhance central serotoninergic transmission diminish elective carbohydrate consumption by rats. Life Sci. 1979 Mar 5; 24(10):895-903.
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Ozaki Y, Wurtman RJ. Spectral power distribution of light sources affects growth and development of rats. Photochem Photobiol. 1979 Feb; 29(2):339-41.
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Millington WR, McCall AL, Wurtman RJ. Lithium and brain choline levels. N Engl J Med. 1979 Jan 25; 300(4):196-7.
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McCall A, Glaeser BS, Millington W, Wurtman RJ. Monosodium glutamate neurotoxicity, hyperosmolarity, and blood-brain barrier dysfunction. Neurobehav Toxicol. 1979; 1(4):279-83.
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Wurtman RJ, Pardridge WM. Summary: circulating tryptophan, brain tryptophan, and psychiatric disease. J Neural Transm Suppl. 1979; (15):227-36.
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Wurtman RJ. When--and why--should nutritional state control neurotransmitter synthesis? J Neural Transm Suppl. 1979; (15):69-79.
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Scriabine A, Ludden CT, Sweet CS, Porter CC, Ulm EH, Stone CA, Watkins CJ, Wurtman RJ, Cronin BL. Antihypertensive activity of metyrosine in spontaneously hypertensive rats and its enhancement by carbidopa. Clin Sci Mol Med Suppl. 1978 Dec; 4:255s-257s.
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Lynch HJ, Jimerson DC, Ozaki Y, Post RM, Bunney WE, Wurtman RJ. Entrainment of rhythmic melatonin secretion in man to a 12-hour phase shift in the light/dark cycle. Life Sci. 1978 Oct 16; 23(15):1557-63.
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Hirsch MJ, Wurtman RJ. Lecithin consumption increases acetylcholine concentrations in rat brain and adrenal gland. Science. 1978 Oct 13; 202(4364):223-5.
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Pettibone DJ, Wurtman RJ, Leeman SE. D-amphetamine administration reduces substance P concentration in the rat striatum. Psychopharmacol Bull. 1978 Oct; 14(4):24-6.
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Millington WR, McCall AL, Wurtman RJ. Deanol acetamidobenzoate inhibits the blood-brain barrier transport of choline. Ann Neurol. 1978 Oct; 4(4):302-6.
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Wurtman RJ. Nutritional and precursor control of brain acetylcholine synthesis. Psychopharmacol Bull. 1978 Oct; 14(4):53-5.
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Hirsch MJ, Growdon JH, Wurtman RJ. Relations between dietary choline or lecithin intake, serum choline levels, and various metabolic indices. Metabolism. 1978 Aug; 27(8):953-60.
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Roel LE, Moskowitz MA, Rubin D, Markovitz D, Lytle LD, Munro HN, Wurtman RJ. In vivo inhibition of rat brain protein synthesis by d-amphetamine. J Neurochem. 1978 Jul; 31(1):341-5.
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Airoldi L, Watkins CJ, Wiggins JF, Wurtman RJ. Effect of pyridoxine on the depletion of tissue pyridoxal phosphate by carbidopa. Metabolism. 1978 Jul; 27(7):771-9.
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Growdon JH, Gelenberg AJ, Doller J, Hirsch MJ, Wurtman RJ. Lecithin can suppress tardive dyskinesia. N Engl J Med. 1978 May 4; 298(18):1029-30.
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Gibson CJ, Wurtman RJ. Physiological control of brain norepinephrine synthesis by brain tyrosine concentration. Life Sci. 1978 Apr 24; 22(16):1399-405.
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Scally MC, Ulus IH, Wurtman RJ, Pettibone DJ. Regional distribution of neurotransmitter-synthesizing enzymes and substance P within the rat corpus striatum. Brain Res. 1978 Mar 31; 143(3):556-60.
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Wurtman RJ, Growdon JH. Dietary enhancement of CNS neurotransmitters. Hosp Pract. 1978 Mar; 13(3):71-7.
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Pettibone DJ, Wurtman RJ, Leeman SE. D-amphetamine administration reduces substance P concentration in the rat striatum. Biochem Pharmacol. 1978 Mar 1; 27(5):839-12.
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Ulus IH, Scally MC, Wurtman RJ. Enhancement by choline of the induction of adrenal tyrosine hydroxylase by phenoxybenzamine, 6-hydroxydopamine, insulin or exposure to cold. J Pharmacol Exp Ther. 1978 Mar; 204(3):676-82.
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Wurtman RJ. Physiological effects of melatonin. Chairman's introduction. J Neural Transm Suppl. 1978; (13):205-7.
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Sahakian BJ, Growdon JH, Millington WR, Barr JK, Wurtman RJ. The effects of cholinergic agonists on apomorphine-induced stereotyped behavior in the rat. Commun Psychopharmacol. 1978; 2(3):255-62.
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Wurtman RJ, Ordonez LA. Effects of exogenous L-dopa on the metabolism of methionine and S-adenosylmethionine in the brain. Monogr Gesamtgeb Psychiatr Psychiatry Ser. 1978; 18:132-43.
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Lynch HJ, Ozaki Y, Wurtman RJ. The measurement of melatonin in mammalian tissues and body fluids. J Neural Transm Suppl. 1978; (13):251-64.
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Scally MC, Ulus IH, Wurtman RJ. Choline administration to the rat increases urinary catecholamines. J Neural Transm. 1978; 43(2):103-12.
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Weitzman ED, Weinberg U, D'Eletto R, Lynch H, Wurtman RJ, Czeisler C, Erlich S. Studies of the 24 hour rhythm of melatonin in man. J Neural Transm Suppl. 1978; (13):325-37.
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Wurtman RJ, Ozaki Y. Physiological control of melatonin synthesis and secretion: mechanisms, generating rhythms in melatonin, methoxytryptophol, and arginine vasotocin levels and effects on the pineal of endogenous catecholamines, the estrous cycle, and environmental lighting. J Neural Transm Suppl. 1978; (13):59-70.
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Ozaki Y, Wurtman RJ, Alonso R, Lynch HJ. Melatonin secretion decreases during the proestrous stage of the rat estrous cycle. Proc Natl Acad Sci U S A. 1978 Jan; 75(1):531-4.
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Zavisca FG, Wurtman RJ. Effects of neutral amino acids on the antihypertensive action of methyldopa in spontaneously hypertensive rats. J Pharm Pharmacol. 1978 Jan; 30(1):60-2.
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Fernstrom JD, Arnold MA, Wurtman RJ, Hammarstrom-Wiklund B, Munro HN, Davidson CS. Diurnal variations in plasma insulin concentrations in normal and cirrhotic subjects: effect of dietary protein. J Neural Transm Suppl. 1978; (14):133-42.
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Wurtman JJ, Wurtman RJ. Fenfluramine and fluoxetine spare protein consumption while suppressing caloric intake by rats. Science. 1977 Dec 16; 198(4322):1178-80.
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Reinhard JF, Wurtman RJ. Relation between brain 5-HIAA levels and the release of serotonin into brain synapses. Life Sci. 1977 Dec 15; 21(12):1741-6.
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Lavyne MH, Koltun WA, Clement JA, Rosene DL, Pickren KS, Zervas NT, Wurtman RJ. Decrease in neostriatal blood flow after D-amphetamine administration or electrical stimulation of the substantia nigra. Brain Res. 1977 Oct 21; 135(1):77-86.
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Growdon JH, Hirsch MJ, Wurtman RJ, Wiener W. Oral choline administration to patients with tardive dyskinesia. N Engl J Med. 1977 Sep 8; 297(10):524-7.
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Ulus IH, Meyer E, Wurtman RJ, Lytle LD. Trans-synaptic induction of adrenal tyrosine hydroxylase following amphetamine treatment in the rat. Neuropharmacology. 1977 Sep; 16(9):635-7.
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Wurtman RJ. Changing norms: before and after kuhn. Science. 1977 Aug 5; 197(4303):514.
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Nomura M, Colmenares JL, Wurtman RJ. Effect of dietary protein on urinary 5-hydroxyindoleacetic acid levels. J Neurochem. 1977 Aug; 29(2):267-71.
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Wurtman RJ, Hirsch MJ, Growdon JH. Lecithin consumption raises serum-free-choline levels. Lancet. 1977 Jul 9; 2(8028):68-9.
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Ulus IH, Scally MC, Wurtman RJ. Choline potentiates the trans-synaptic induction of adrenal tyrosine hydroxylase by reserpine, probably by enhancing the release of acetylcholine. Life Sci. 1977 Jul 1; 21(1):145-8.
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Wurtman RJ, Moskowitz MA. The pineal organ (Second of two parts). N Engl J Med. 1977 Jun 16; 296(24):1383-6.
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Gibson CJ, Wurtman RJ. Physiological control of brain catechol synthesis by brain tyrosine concentration. Biochem Pharmacol. 1977 Jun 15; 26(12):1137-42.
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Wurtman RJ, Moskowitz MA. The pineal organ (first of two parts). N Engl J Med. 1977 Jun 9; 296(23):1329-33.
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Jimerson DC, Lynch HJ, Post RM, Wurtman RJ, Bunney WE. Urinary melatonin rhythms during sleep deprivation in depressed patients and normals. Life Sci. 1977 May 1; 20(9):1501-8.
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Growdon JH, Cohen EL, Wurtman RJ. Huntington's disease: clinical and chemical effects of choline administration. Ann Neurol. 1977 May; 1(5):418-22.
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Hirsch MJ, Growdon JH, Wurtman RJ. Increase in hippocampal acetylcholine after choline administration. Brain Res. 1977 Apr 15; 125(2):383-5.
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Moskowitz MA, Rubin D, Liebschutz J, Munro HN, Nowak TS, Wurtman RJ. The permissive role of hyperthermia in the disaggregation of brain polysomes by L-dopa or D-amphetamine. J Neurochem. 1977 Apr; 28(4):779-82.
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Growdon JH, Cohen EL, Wurtman RJ. Treatment of brain disease with dietary precursors of neurotransmitters. Ann Intern Med. 1977 Mar; 86(3):337-9.
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Liebschutz J, Airoldi L, Brownstein MJ, Chinn NG, Wurtman RJ. Regional distribution of endogenous and parenteral glutamate, aspartate and glutamine in rat brain. Biochem Pharmacol. 1977 Mar 1; 26(5):443-6.
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Sole MJ, Wurtman RJ, Lo CM, Kamble AB, Sonnenblick EH. Tyrosine hydroxylase activity in the heart of the cardiomyopathic syrian hamster. J Mol Cell Cardiol. 1977 Mar; 9(3):225-33.
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Ulus IH, Hirsch MJ, Wurtman RJ. Trans-synaptic induction of adrenomedullary tyrosine hydroxylase activity by choline: evidence that choline administration can increase cholinergic transmission. Proc Natl Acad Sci U S A. 1977 Feb; 74(2):798-800.
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Fernstrom JD, Munro HN, Wurtman RJ. Brain tryptophan in rats on a high fat diet. Nature. 1977 Jan 20; 265(5591):277.
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Wurtman RJ. Brain chemistry. Science. 1977 Jan 7; 195(4273):60.
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Wurtman RJ, Watkins CJ. Suppression of noradrenaline synthesis in sympathetic nerves by carbidopa, an inhibitor of peripheral dopa decarboxylase. Nature. 1977 Jan 6; 265(5589):79-80.
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Growdon JH, Cohen EL, Wurtman RJ. Effects of oral choline administration on serum and CSF choline levels in patients with Huntington's disease. J Neurochem. 1977 Jan; 28(1):229-31.
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Lynch HJ, Ho M, Wurtman RJ. The adrenal medulla may mediate the increase in pineal melatonin synthesis induced by stress, but not that caused by exposure to darkness. J Neural Transm. 1977; 40(2):87-97.
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Botticelli LJ, Lytle LD, Wurtman RJ. Choline-induced attenuation of morphine analgesia in the rat. Commun Psychopharmacol. 1977; 1(6):519-23.
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Scally MC, Ulus I, Wurtman RJ. Brain tyrosine level controls striatal dopamine synthesis in haloperidol-treated rats. J Neural Transm. 1977; 41(1):1-6.
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Ulus IH, Wurtman RJ. Choline administration: activation of tyrosine hydroxylase in dopaminergic neurons of rat brain. Science. 1976 Dec 3; 194(4269):1060-1.
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Scriabine A, Ludden CT, Stone CA, Wurtman RJ, Watkins CJ. Enhancement of the anti-hypertensive effect of methyldopa and other anti-hypertensive drugs by carbidopa in spontaneously hypertensive rats. Clin Sci Mol Med Suppl. 1976 Dec; 3:407s-410s.
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Jacoby JH, Howd RA, Levin MS, Wurtman RJ. Mechanisms by which quipazine, a putative serotonin receptor agonist, alters brain 5-hydroxyindole metabolism. Neuropharmacology. 1976 Sep; 15(9):529-34.
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Wurtman RJ, Fernstrom JD. Control of brain neurotransmitter synthesis by precursor availability and nutritional state. Biochem Pharmacol. 1976 Aug 1; 25(15):1691-6.
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Lo CM, Kwok ML, Wurtman RJ. O-methylation and decarboxylation of alpha-methyldopa in brain and spinal cord: depletion of S-adenosylmethionine and accumulation of metabolites in catecholaminergic neurones. Neuropharmacology. 1976 Jul; 15(7):395-402.
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Ozaki Y, Lynch HJ, Wurtman RJ. Melatonin in rat pineal, plasma, and urine: 24-hour rhythmicity and effect of chlorpromazine. Endocrinology. 1976 Jun; 98(6):1418-24.
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Houd RA, Seo KS, Wurtman RJ. Rat liver N-acetyltransferase: inhibition by melatonin. Biochem Pharmacol. 1976 Apr 15; 25(8):977-8.
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Zacharias L, Rand WM, Wurtman RJ. A prospective study of sexual development and growth in American girls: the statistics of menarchie. Obstet Gynecol Surv. 1976 Apr; 31(4):325-37.
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Cohen EL, Wurtman RJ. Brain acetylcholine: control by dietary choline. Science. 1976 Feb 13; 191(4227):561-2.
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Chiel HJ, Wurtman RJ. Suppression of amphetamine-induced hypothermia by the neutral amino acid valine. Psychopharmacol Commun. 1976; 2(3):207-17.
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Minneman KP, Wurtman RJ. The pharmacology of the pineal gland. Annu Rev Pharmacol Toxicol. 1976; 16:33-51.
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Wurtman RJ, Cardinali DP. The effects of light on man. Birth Defects Orig Artic Ser. 1976; 12(2):100-13.
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Colmenares JL, Wurtman RJ, Fernstrom JD. Effects of ingestion of a carbohydrate-fat meal on the levels and synthesis of 5-hydroxyindoles in various regions of the rat central nervous system. J Neurochem. 1975 Dec; 25(6):825-9.
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Sole MJ, Lo CM, Laird CW, Sonnenblick EH, Wurtman RJ. Norepinephrine turnover in the heart and spleen of the cardiomyopathic Syrian hamster. Circ Res. 1975 Dec; 37(6):855-62.
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Lynch HJ, Ozaki Y, Shakal D, Wurtman RJ. Melatonin excretion of man and rats: effect of time of day, sleep, pinealectomy and food consumption. Int J Biometeorol. 1975 Dec; 19(4):267-79.
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Jacoby JH, Shabshelowitz H, Fernstrom JD, Wurtman RJ. The mechanism by which methiothepin, a putative serotonin receptor antagonist, icnreses brain 5-hydroxyindole levels. J Pharmacol Exp Ther. 1975 Nov; 195(2):257-64.
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Jacoby JH, Mueller G, Wurtman RJ. Thyroid state and brain monoamine metabolism. Endocrinology. 1975 Nov; 97(5):1332-5.
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Minneman KP, Wurtman RJ. Effects of pineal compounds on mammals. Life Sci. 1975 Oct 15; 17(8):1189-99.
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Munro HN, Fernstrom JD, Wurtman RJ. Letter: Plasma neutral aminoacids and tryptophan in cirrhosis. Lancet. 1975 Aug 30; 2(7931):419.
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Moskowitz MA, Meyer E, Wurtman RJ, Lavyne MH, Zervas T. Attenuation by catecholamine antagonists of the hypothermia that follows cerebral infarction in gerbils. Life Sci. 1975 Aug 15; 17(4):597-602.
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Versteeg DH, Wurtman RJ. Effect of ACTH4-10 on the rate of synthesis of [3H]catecholamines in the brains of intact, hypophysectomized and adrenalectomized rats. Brain Res. 1975 Aug 15; 93(3):552-7.
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Moskowitz MA, Wurtman RJ. Catecholamines and neurologic diseases (second of two parts). N Engl J Med. 1975 Aug 14; 293(7):332-8.
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Moskowitz MA, Wurtman RJ. Catecholamines and neurologic diseases (first of two parts). N Engl J Med. 1975 Aug 7; 293(6):274-80.
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Wurtman RJ. The effects of light on the human body. Sci Am. 1975 Jul; 233(1):69-77.
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Wurtman RJ, Fernstrom JD. Control of brain monoamine synthesis by diet and plasma amino acids. Am J Clin Nutr. 1975 Jun; 28(6):638-47.
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Weiss BF, Liebschutz JL, Wurtman RJ, Munro HN. Participation of dopamine- and serotonin- receptors in the disaggregation of brain polysomes by L-dopa and L-5-HTP. J Neurochem. 1975 Jun; 24(6):1191-5.
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Lavyne MH, Moskowitz MA, Larin F, Zervas NT, Wurtman RJ. Brain H-3-catecholamine metabolism in experimental cerebral ischemia. Neurology. 1975 May; 25(5):483-5.
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Cohen EL, Wurtman RJ. Brain acetylcholine: increase after systemic choline administration. Life Sci. 1975 Apr 1; 16(7):1095-102.
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Munro HN, Fernstrom JD, Wurtman RJ. Insulin, plasma aminoacid imbalance, and hepatic coma. Lancet. 1975 Mar 29; 1(7909):722-4.
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Lavyne M, Wurtman RJ, Moskowitz M, Zervas N. Brain catecholamines and blood flow. Life Sci. 1975 Feb 15; 16(4):475-86.
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Yehuda S, Wurtman RJ. Dopaminergic neurons in the nigro-striatal and mesolimbic pathways: mediation of specific effects of D-amphetamine. Eur J Pharmacol. 1975 Feb; 30(2):154-8.
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Lynch HJ, Wurtman RJ, Moskowitz MA, Archer MC, Ho MH. Daily rhythm in human urinary melatonin. Science. 1975 Jan 17; 187(4172):169-71.
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Lynch HJ, Hsuan M, Wurtman RJ. Sympathetic neural control of indoleamine metabolism in the rat pineal gland. Adv Exp Med Biol. 1975; 54:93-114.
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Jacoby JH, Colmenares JL, Wurtman RJ. Failure of decreased serotonin uptake or monoamine oxidase inhibition to block the acceleration in brain 5-hydroxyindole synthesis that follows food consumption. J Neural Transm. 1975; 37(1):25-32.
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Wurtman RJ. The effects of light on man and other mammals. Annu Rev Physiol. 1975; 37:467-83.
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Wurtman RJ, Shein HM. Lack of effect of increased pineal serotonin content on H3-tryptophan uptake. J Neural Transm. 1975; 36(3-4):177-81.
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Lavyne M, Moskowitz M, Zervas N, Wurtman R. Rotational behavior in gerbils following unilateral common carotid artery ligation. J Neural Transm. 1975; 36(2):83-9.
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Cardinali DP, Wurtman RJ. Methods for assessing the bioligical activity of the mammalian pineal organ. Methods Enzymol. 1975; 39:376-97.
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Madras BK, Cohen EL, Messing R, Munro HN, Wurtman RJ. Relevance of free tryptophan in serum to tissue tryptophan concentrations. Metabolism. 1974 Dec; 23(12):1107-16.
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Minneman KP, Lynch H, Wurtman RJ. Relationship between environmental light intensity and retina-mediated suppression of rat pineal serotonin-N-acetyl-transferase. Life Sci. 1974 Nov 15; 15(10):1791-6.
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Wurtman RJ. Proceedings: Neuroendocrine transducers: brain monoamines and the control of hypothalamo-pituitary function. Psychopharmacol Bull. 1974 Oct; 10(4):7-9.
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Wurtman RJ. Daily rhythms in tyrosine transaminase and other hepatic enzymes that metabolize amino acids: mechanisms and possible consequences. Life Sci. 1974 Sep 1; 15(5):827-47.
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Wurtman RJ, Larin F, Mostafapour S, Fernstrom JD. Brain catechol synthesis: control by train tyrosine concentration. Science. 1974 Jul 12; 185(4146):183-4.
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Rubin RA, Ordonez LA, Wurtman RJ. Physiological dependence of brain methionine and S-adenosylmethionine concentrations on serum amino acid pattern. J Neurochem. 1974 Jul; 23(1):227-31.
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Roel LE, Schwartz SA, Weiss BF, Munro HN, Wurtman RJ. In vivo inhibition of rat brain protein synthesis by L-dopa. J Neurochem. 1974 Jul; 23(1):233-9.
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Yehuda S, Wurtman RJ. Paradoxical effects of d-amphetamine on behavioral thermoregulation: possible mediation by brain dopamine. J Pharmacol Exp Ther. 1974 Jul; 190(1):118-22.
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Ordonez LA, Arbrus M, Boyson S, Goodman MN, Ruderman NB, Wurtman RJ. Skeletal muscle: reservoir for exogenous L-dopa. J Pharmacol Exp Ther. 1974 Jul; 190(1):187-91.
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Yehuda S, Wurtman RJ. Paradoxical thermoregulatory behaviour in rats induced by (plus)-amphetamine: blockade by alpha-adrenoceptor or dopamine receptor blocking agents. J Pharm Pharmacol. 1974 Mar; 26(3):210-2.
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Fernstrom JD, Wurtman RJ. Nutrition and the brain. Sci Am. 1974 Feb; 230(2):84-91.
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Ordonez LA, Wurtman RJ. Folic acid deficiency and methyl group metabolism in rat brain: effects of L-dopa. Arch Biochem Biophys. 1974 Feb; 160(2):372-6.
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Hoeldtke R, Rogawski M, Wurtman RJ. Effect of selective destruction of central and peripheral catecholamine-containing neurones with 6-hydroxydopamine on catecholamine excretion in the rat. Br J Pharmacol. 1974 Feb; 50(2):265-70.
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Zervas NT, Hori H, Negora M, Wurtman RJ, Larin F, Lavyne MH. Reduction in brain dopamine following experimental cerebral ischaemia. Nature. 1974 Feb 1; 247(439):283-4.
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Chiel H, Yehuda S, Wurtman RJ. Development of tolerance in rats to the hypothermic effects of D-amphetamine and apomorphine. Life Sci. 1974 Feb 1; 14(3):483-8.
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Hurko O, Elster P, Wurtman RJ. Adenylate cyclase activity in bovine adrenal medulla. Endocrinology. 1974 Feb; 94(2):591-3.
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Weiss BF, Roel LE, Munro HN, Wurtman RJ. The effect of L-DOPA on brain polysomes and protein synthesis: probable mediation by intracellular dopamine. Adv Neurol. 1974; 5:87-99.
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Hoeldtke RD, Wurtman RJ. Synthesis of DOPA in rat stomach following ingestion of cereals. Metabolism. 1974 Jan; 23(1):25-31.
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Fernstrom JD, Wurtman RJ. Control of brain serotonin levels by the diet. Adv Biochem Psychopharmacol. 1974; 11(0):133-42.
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Wurtman RJ, Zervas NT. Monoamine neurotransmitters and the pathophysiology of stroke and central nervous system trauma. J Neurosurg. 1974 Jan; 40(1):34-6.
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Wurtman RJ, Fernstrom JD. Control of brain serotonin by the diet. Adv Neurol. 1974; 5:19-29.
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Madras BK, Cohen EL, Munro HN, Wurtman RJ. Elevation of serum free tryptophan, but not brain tryptophan, by serum nonesterified fatty acids. Adv Biochem Psychopharmacol. 1974; 11(0):143-51.
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Hoeldtke RD, Wurtman RJ. Cereal ingestion and catecholamine excretion. Metabolism. 1974 Jan; 23(1):33-41.
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Wurtman RJ, Moskowitz MA. Brain catecholamines and neurological disease. Trans Am Neurol Assoc. 1974; 99:149-59.
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Ordóñez LA, Wurtman RJ. Enzymes catalyzing the de novo synthesis of methyl groups in the brain and other tissues of the rat. J Neurochem. 1973 Dec; 21(6):1447-55.
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Shoemaker WJ, Wurtman RJ. Effect of perinatal undernutrition on the metabolism of catecholamines in the rat brain. J Nutr. 1973 Nov; 103(11):1537-47.
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McGuire RA, Rand WM, Wurtman RJ. Entrainment of the body temperature rhythm in rats: effect of color and intensity of environmental light. Science. 1973 Sep 7; 181(4103):956-7.
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Ross DS, Fernstrom JD, Wurtman RJ. The role of dietary protein in generating daily rhythms in rat liver tryptophan pyrrolase and tyrosine transaminase. Metabolism. 1973 Sep; 22(9):1175-84.
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Pohorecky LA, Baliga BS, Wurtman RJ, Bartter FC. Adrenocortical control of catecholamine metabolism in the dog adrenal medulla: relationship to protein synthesis. Endocrinology. 1973 Sep; 93(3):566-74.
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Voelkel EF, Tashjian AH, Davidoff FF, Cohen RB, Perlia CP, Wurtman RJ. Concentrations of calcitonin and catecholamines in pheochromocytomas, a mucosal neuroma and medullary thyroid carcinoma. J Clin Endocrinol Metab. 1973 Aug; 37(2):297-307.
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Madras BK, Cohen EL, Fernstrom JD, Larin F, Munro HN, Wurtman RJ. Letter: Dietary carbohydrate increases brain tryptophan and decreases free plasma tryptophan. Nature. 1973 Jul 6; 244(5410):34-5.
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Wurtman RJ. Biogenic amines and endocrine function. Introduction: neuroendocrine transducers and monoamines. Fed Proc. 1973 Jul; 32(7):1769-71.
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Lynch HJ, Eng JP, Wurtman RJ. Control of pineal indole biosynthesis by changes in sympathetic tone caused by factors other than environmental lighting. Proc Natl Acad Sci U S A. 1973 Jun; 70(6):1704-7.
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Baliga BS, Pohorecky LA, Munro HN, Wurtman RJ. Control of adrenal medullary protein synthesis by corticosteroids. Biochim Biophys Acta. 1973 Mar 19; 299(2):337-43.
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Hoeldtke RD, Wurtman RJ. Excretion of catecholamines and catecholamine metabolites in kwashiorkor. Am J Clin Nutr. 1973 Feb; 26(2):205-10.
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Lipsett D, Madras BK, Wurtman RJ, Munro HN. Serum tryptophan level after carbohydrate ingestion: selective decline in non-albumin-bound tryptophan coincident with reduction in serum free fatty acids. Life Sci II. 1973 Jan 22; 12(2):57-64.
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Romero JA, Lytle LD, Ordonez LA, Wurtman RJ. Effects of L-dopa administration of the concentrations of dopa, dopamine and norepinephrine in various rat tissues. J Pharmacol Exp Ther. 1973 Jan; 184(1):67-72.
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Zschaeck LL, Wurtman RJ. Brain 3 H-catechol synthesis and the vaginal estrous cycle. Neuroendocrinology. 1973; 11(3):144-9.
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Munro HN, Roel L, Wurtman RJ. Inhibition of brain protein synthesis by doses of L-DOPA that disaggregate brain polyribosomes. J Neural Transm. 1973; 34(4):321-3.
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Ordonez LA, Wurtman RJ. Methylation of exogenous 3,4-dihydroxyphenylalanine (,dopa)--effects on methyl group metabolism. Biochem Pharmacol. 1973 Jan 1; 22(1):134-7.
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Hyyppä M, Wurtman RJ. Biogenic amines in the pituitary gland: what is their origin and function? Pituitary indolamines. Prog Brain Res. 1973; 39:211-5.
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Hyyppä MT, Cardinali DP, Wurtman RJ. Sex-dependent increase in pineal hydroxyindole-O-methyl transferase activity after a single intraventricular injection of 6-hydroxydopamine to newborn rats. Neuroendocrinology. 1973; 11(5):274-83.
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Cardinali DP, Hyyppä MT, Wurtman RJ. Fate of intracisternally injected melatonin in the rat brain. Neuroendocrinology. 1973; 12(1):30-40.
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Hyyppä MT, Cardinali DP, Baumgarten HG, Wurtman RJ. Rapid accumulation of H3-serotonin in brains of rats receiving intraperitoneal H3-tryptophan: effects of 5,6-dihydroxytryptamine or female sex hormones. J Neural Transm. 1973; 34(2):111-24.
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Yehuda S, Wurtman RJ. Release of brain dopamine as the probable mechanism for the hypothermic effect of D-amphetamine. Nature. 1972 Dec 22; 240(5382):477-8.
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Cardinali DP, Lynch HJ, Wurtman RJ. Binding of melatonin to human and rat plasma proteins. Endocrinology. 1972 Nov; 91(5):1213-8.
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Fernstrom JD, Wurtman RJ. Brain serotonin content: physiological regulation by plasma neutral amino acids. Science. 1972 Oct 27; 178(4059):414-6.
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Lytle LD, Shoemaker WJ, Cottman K, Wurtman RJ. Long-term effects of postnatal 6-hydroxydopamine treatment on tissue catecholamine levels. J Pharmacol Exp Ther. 1972 Oct; 183(1):56-64.
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Cardinali DP, Larin F, Wurtman RJ. Action spectra for effects of light on hydroxyindole-o-methyl transferases in rat pineal, retina and harderian gland. Endocrinology. 1972 Oct; 91(4):877-86.
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Yehuda S, Wurtman RJ. The effects of D-amphetamine and related drugs on colonic temperatures of rats kept at various ambient temperatures. Life Sci I. 1972 Sep 15; 11(18):851-9.
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Weiss BF, Munro HN, Ordonez LA, Wurtman RJ. Dopamine: mediator of brain polysome disaggregation after L-dopa. Science. 1972 Aug 18; 177(4049):613-6.
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Hyyppä MT, Wurtman RJ. Time-dependent changes in brain 3 H-norepinephrine disappearance caused by L-DOPA administration. Life Sci I. 1972 Aug 1; 11(15):713-21.
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Cardinali DP, Larin F, Wurtman RJ. Control of the rat pineal gland by light spectra. Proc Natl Acad Sci U S A. 1972 Aug; 69(8):2003-5.
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Pohorecky LA, Wurtman RJ, Taam D, Fine J. Effects of endotoxin on monoamine metabolism in the rat. Proc Soc Exp Biol Med. 1972 Jul; 140(3):739-46.
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Cardinali DP, Wurtman RJ. Hydroxyindole-O-methyl transferases in rat pineal, retina and harderian gland. Endocrinology. 1972 Jul; 91(1):247-52.
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Chou C, Wurtman R. Probable nutritional basis for effect of estradiol on rat liver catechol-O-methyl transferase. Life Sci I. 1972 Jun 15; 11(12):581-5.
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Wurtman RJ, Pohorecky LA, Baliga BS. Adrenocortical control of the biosynthesis of epinephrine and proteins in the adrenal medulla. Pharmacol Rev. 1972 Jun; 24(2):411-26.
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Hoeldtke R, Baliga BS, Issenberg P, Wurtman RJ. Dihydroxyphenylalanine in rat food containing wheat and oats. Science. 1972 Feb 18; 175(4023):761-2.
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Romero JA, Chalmers JP, Cottman K, Lytle LD, Wurtman RJ. Regional effects of L-dihydroxyphenylalanine (L-dopa) on norepinephrine metabolism in rat brain. J Pharmacol Exp Ther. 1972 Feb; 180(2):277-85.
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Vlahakes GJ, Wurtman RJ. A Mg 2+ dependent hydroxyindole O-methyltransferase in rat Harderian gland. Biochim Biophys Acta. 1972 Jan 28; 261(1):194-7.
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Wurtman RJ. Effect of L-DOPA on S-adenosylmethionine levels and norepinephrine metabolism in rat brain. Adv Biochem Psychopharmacol. 1972; 6:241-6.
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Lytle LD, Hurko O, Romero JA, Cottman K, Leehey D, Wurtman RJ. The effects of 6-hydroxydopamine pretreatment on the accumulation of dopa and dopamine in brain and peripheral organs following L-dopa administration. J Neural Transm. 1972; 33(1):63-71.
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Fernstrom JD, Wurtman RJ. Brain serotonin content: increase following ingestion of carbohydrate diet. Science. 1971 Dec 3; 174(4013):1023-5.
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Fernstrom JD, Wurtman RJ. Effect of chronic corn consumption on serotonin content of rat brain. Nat New Biol. 1971 Nov 10; 234(45):62-4.
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Zigmond MJ, Chalmers JP, Simpson JR, Wurtman RJ. Effect of lateral hypothalamic lesions on uptake of norepinephrine by brain homogenates. J Pharmacol Exp Ther. 1971 Oct; 179(1):20-8.
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Wurtman RJ, Shein HM, Larin F. Mediation by -adrenergic receptors of effect of norepinephrine on pineal synthesis of ( 14 C)serotonin and ( 14 C)melatonin. J Neurochem. 1971 Sep; 18(9):1683-7.
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Weiss BF, Munro HN, Wurtman RJ. L-dopa: disaggregation of brain polysomes and elevation of brain tryptophan. Science. 1971 Aug 27; 173(3999):833-5.
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Shein HM, Wurtman RJ. Stimulation of [ 14 C] tryptophan 5-hydroxylation by norepinephrine and dibutyryl adenosine 3', 5' monophosphate in rat pineal organ cultures. Life Sci I. 1971 Aug 15; 10(16):935-40.
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Fernstrom JD, Larin F, Wurtman RJ. Daily variations in the concentrations of individual amino acids in rat plasma. Life Sci I. 1971 Jul 15; 10(14):813-9.
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Fernstrom JD, Wurtman RJ. Brain serotonin content: physiological dependence on plasma tryptophan levels. Science. 1971 Jul 9; 173(3992):149-52.
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Chalmers JP, Wurtman RJ. The fate of intracisternally administered norepinephrine-3H in the brain and spinal cord of the rabbit. J Pharmacol Exp Ther. 1971 Jul; 178(1):8-19.
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Chalmers JP, Wurtman RJ. Participation of central noradrenergic neurons in arterial baroreceptor reflexes in the rabbit. Circ Res. 1971 Apr; 28(4):480-91.
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Shoemaker WJ, Wurtman RJ. Perinatal undernutrition: accumulation of catecholamines in rat brain. Science. 1971 Mar 12; 171(3975):1017-9.
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Shein HM, Wilson S, Larin F, Wurtman RJ. Stimulation of(14C)serotonin synthesis from (14C)tryptophan by mescaline in rat pineal organ cultures. Life Sci II. 1971 Mar 8; 10(5):273-82.
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Pohorecky LA, Wurtman RJ. Adrenocortical control of epinephrine synthesis. Pharmacol Rev. 1971 Mar; 23(1):1-35.
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Wurtman RJ, Anton-Tay F. Analysis of norepinephrine metabolism in nonsteady states. Neurosci Res Program Bull. 1971 Mar; 9(2):254-6.
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Chalmers JP, Baldessarini RJ, Wurtman RJ. Effects of L-dopa on norepinephrine metabolism in the brain. Proc Natl Acad Sci U S A. 1971 Mar; 68(3):662-6.
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Wurtman RJ. Possible sites of action of monoamines in hypothalamohypophyseal function. Neurosci Res Program Bull. 1971 Mar; 9(2):214-7.
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Wurtman RJ. Neuroendocrine transduction. Neurosci Res Program Bull. 1971 Mar; 9(2):182-7.
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Neer RM, Davis TR, Walcott A, Koski S, Schepis P, Taylor I, Thorington L, Wurtman RJ. Stimulation by artificial lighting of calcium absorption in elderly human subjects. Nature. 1971 Jan 22; 229(5282):255-7.
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Wurtman RJ, Pohorecky LA. Adrenocortical control of epinephrine synthesis in health and disease. Adv Metab Disord. 1971; 5:53-76.
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Zacharias L, Wurtman RJ, Schatzoff M. Sexual maturation in contemporary American girls. Am J Obstet Gynecol. 1970 Nov 1; 108(5):833-46.
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Wurtman RJ, Chou C, Rose C. The fate of C14-dihydroxyphenylalanine (C14-dopa) in the whole mouse. J Pharmacol Exp Ther. 1970 Sep; 174(3):351-6.
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Wurtman RJ, Matthysse S, Stephenson J, Baldessarini R. L-dihydroxyphenylalanine: effect on S-adenosylmethionine in brain. Science. 1970 Jul 24; 169(3943):395-7.
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Piezzi RS, Wurtman RJ. Pituitary serotonin content: effects of melatonin or deprivation of water. Science. 1970 Jul 17; 169(3942):285-6.
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Pohorecky LA, Piezzi RS, Wurtman RJ. Steroid induction of phenylethanolamine-N-methyl transferase in adrenomedullary explants: independence of adrenal innervation. Endocrinology. 1970 Jun; 86(6):1466-8.
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Piezzi RS, Larin F, Wurtman RJ. Serotonin, 5-hydroxyindoleacetic acid (5-HIAA), and monoamide oxidase in the bovine median eminence and pituitary gland. Endocrinology. 1970 Jun; 86(6):1460-2.
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Wurtman RJ. Effects of light on metabolic processes. Birth Defects Orig Artic Ser. 1970 Jun; 6(2):60-2.
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Rose CM, Wurtman RJ. Daily rhythms in content and utilization of tyrosine in the whole mouse. Nature. 1970 May 2; 226(5244):454-5.
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Zigmond MJ, Wurtman RJ. Daily rhythm in the accumulation of brain catechol-amines synthesized fom circulating H3-tyrosine. J Pharmacol Exp Ther. 1970 Apr; 172(2):416-22.
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Wurtman RJ, Neer RM. Good light and bad. N Engl J Med. 1970 Feb 12; 282(7):394-5.
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Cohn C, Joseph D, Larin F, Shoemaker WJ, Wurtman RJ. Influence of feeding habits and adrenal cortex on diurnal rhythm of hepatic tyrosine transaminase activity. Proc Soc Exp Biol Med. 1970 Feb; 133(2):460-2.
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Anton-Tay F, Anton SM, Wurtman RJ. Mechanism of changes in brain norepinephrine metabolism after ovariectomy. Neuroendocrinology. 1970; 6(5):265-73.
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Shein HM, Larin F, Wurtman RJ. Lack of a direct effect of morphine on the synthesis of pineal 14-C-indoles in organ culture. Life Sci. 1970 Jan 1; 9(1):29-33.
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Wurtman RJ. Catecholamines and neurologic diseases. N Engl J Med. 1970 Jan 1; 282(1):45-6.
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Wurtman RJ. The pineal gland: endocrine interrelationships. Adv Intern Med. 1970; 16:155-69.
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Pohorecky LA, Larin F, Wurtman RJ. Mechanism of changes in brain norepinephrine levels following olfactory bulb lesions. Life Sci. 1969 Dec 1; 8(23):1309-17.
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Wurtman RJ, Weisel J. Environmental lighting and neuroendocrine function: relationship between spectrum of light source and gonadal growth. Endocrinology. 1969 Dec; 85(6):1218-21.
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Shein HM, Wurtman RJ. Cyclic adenosine monophosphate: stimulation of melatonin and serotonin synthesis in cultured rat pineals. Science. 1969 Oct 24; 166(3904):519-20.
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Fishman B, Wurtman RJ, Munro HN. Daily rhythms in hepatic polysome profiles and tyrosine transaminase activity: role of dietary protein. Proc Natl Acad Sci U S A. 1969 Oct; 64(2):677-82.
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Wurtman RJ, Anton-Tay F, Anton S. On the use of synthesis inhibitors to estimate brain norepinephrine synthesis in gonadectomized rats. Life Sci. 1969 Sep 1; 8(17):1015-22.
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Anton-Tay F, Pelham RW, Wurtman RJ. Increased turnover of 3H-norepinephrine in rat brain following castration or treatment with ovine follicle-stimulating hormone. Endocrinology. 1969 Jun; 84(6):1489-92.
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Wurtman RJ. The pineal gland in relation to reproduction. Am J Obstet Gynecol. 1969 Jun 1; 104(3):320-6.
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Zigmond MJ, Shoemaker WJ, Larin F, Wurtman RJ. Hepatic tyrosine transaminase rhythm: interaction of environmental lighting, food consumption and dietary protein content. J Nutr. 1969 May; 98(1):71-5.
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Zacharias L, Wurtman RJ. Blindness and menarche. Obstet Gynecol. 1969 May; 33(5):603-8.
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Zacharias L, Wurtman RJ. Age at menarche. Genetic and environmentalinfluences. N Engl J Med. 1969 Apr 17; 280(16):868-75.
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Pohorecky LA, Zigmond MJ, Heimer L, Wurtman RJ. Olfactory bulb removal: effects on brain norepinephrine. Proc Natl Acad Sci U S A. 1969 Apr; 62(4):1052-5.
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Wurtman RJ, Shein HM, Axelrod J, Laren F. Incorporation of 14C-tryptophan into 14C-protein by cultured rat pineals: stimulation by l-norepinephrine. Proc Natl Acad Sci U S A. 1969 Mar; 62(3):749-55.
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Pohorecky LA, Zigmond M, Karten H, Wurtman RJ. Enzymatic conversion of norepinephrine to epinephrine by the brain. J Pharmacol Exp Ther. 1969 Feb; 165(2):190-5.
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Anton-Tay F, Wurtman RJ. Regional uptake of 3H-melatonin from blood or cerebrospinal fluid by rat brain. Nature. 1969 Feb 1; 221(5179):474-5.
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Axelrod J, Shein HM, Wurtman RJ. Stimulation of C14-melatonin synthesis from C14-tryptophan by noradrenaline in rat pineal in organ culture. Proc Natl Acad Sci U S A. 1969 Feb; 62(2):544-9.
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Wurtman RJ, Anton-Tay F. The mammalian pineal as a neuroendocrine transducer. Recent Prog Horm Res. 1969; 25:493-522.
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Wurtman RJ. Time-dependent variations in amino acid metabolism: mechanism of the tyrosine transaminase rhythm in rat liver. Adv Enzyme Regul. 1969; 7:57-67.
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Pohorecky LA, Stamm WE, Wurtman RJ. Effects of lighting on epinephrine synthesis in the rat. J Neurovisc Relat. 1969; 31(3):275-9.
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Anton-Tay F, Chou C, Anton S, Wurtman RJ. Brain serotonin concentration: elevation following intraperitoneal administration of melatonin. Science. 1968 Oct 11; 162(3850):277-8.
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Wurtman RJ, Casper A, Pohorecky LA, Bartter FC. Impaired secretion of epinephrine in response to insulin among hypophysectomized dogs. Proc Natl Acad Sci U S A. 1968 Oct; 61(2):522-8.
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Wurtman RJ, Shoemaker WJ, Larin F, Zigmond M. Failure of brain norepinephrine depletion to extinguish the daily rhythm in hepatic tyrosine transaminase activity. Nature. 1968 Sep 7; 219(5158):1049-50.
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Wurtman RJ, Rose CM, Chou C, Larin FF. Daily rhythms in the concentrations of various amino acids in human plasma. N Engl J Med. 1968 Jul 25; 279(4):171-5.
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Wurtman RJ, Zigmond MJ. Pharmacologic tools in autonomic nervous system research. Anesthesiology. 1968 Jul-Aug; 29(4):714-23.
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Wurtman RJ, Axelrod J, Anton-Tay F. Inhibition of the metabolism of H3-melatonin by phenothiazines. J Pharmacol Exp Ther. 1968 Jun; 161(2):367-72.
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Anton-Tay F, Wurtman RJ. Stimulation of hydroxyindole-o-methyl transferase activity in hamster pineal glands by blinding or continuous darkness. Endocrinology. 1968 Jun; 82(6):145-6.
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Wurtman RJ, Larin F. A sensitive and specific isotopic assay for the estimation of tyrosine transaminase. Biochem Pharmacol. 1968 May; 17(5):817-8.
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Wurtman RJ. Estrogen receptor: ambiguities in the use of this term. Science. 1968 Mar 15; 159(3820):1261.
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Anton-Tay F, Wurtman RJ. Norepinephrine: turnover in rat brains after gonadectomy. Science. 1968 Mar 15; 159(3820):1245.
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Wurtman RJ, Larin F, Axelrod J, Shein HM, Rosasco K. Formation of melatonin and 5-hydroxyindole acetic acid from 14C-tryptophan by rat pineal glands in organ culture. Nature. 1968 Mar 9; 217(5132):953-4.
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Orme SK, Wells SA, Rabson AS, Wurtman RJ. In vitro neoplastic transformation of hamster pineal cells by three oncogenic DNA viruses. Cancer. 1968 Mar; 21(3):477-82.
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Wurtman RJ, Shoemaker WJ, Larin F. Mechanism of the daily rhythm in hepatic tyrosine transaminase activity: role of dietary tryptophan. Proc Natl Acad Sci U S A. 1968 Mar; 59(3):800-7.
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Wurtman RJ, Axelrod J, Vesell ES, Ross GT. Species differences in inducibility of phenylethanolamine-N-methyl transferase. Endocrinology. 1968 Mar; 82(3):584-90.
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Manshardt J, Wurtman RJ. Daily rhythm in the noradrenaline content of rat hypothalamus. Nature. 1968 Feb 10; 217(5128):574-5.
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Moore RY, Heller A, Bhatnager RK, Wurtman RJ, Axelrod J. Central control of the pineal gland: visual pathways. Arch Neurol. 1968 Feb; 18(2):208-18.
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Axelrod J, Wurtman RJ. Fate of norepinephrine in sympathetic nerons and by cardiovascular drugs. N Y State J Med. 1968 Jan 15; 68(2):252-6.
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Wurtman RJ, Axelrod J. The formation, metabolism and physiologic effects of melatonin. Adv Pharmacol. 1968; 6(Pt A):141-51.
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Reis DJ, Wurtman RJ. Diurnal changes in brain noradrenalin. Life Sci. 1968 Jan 1; 7(1):91-8.
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Axelrod J, Wurtman RJ. Photic and neural control of indoleamine metabolism in the rat pineal gland. Adv Pharmacol. 1968; 6(Pt A):157-66.
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Wurtman RJ, Chou C, Rose CM. Daily rhythm in tyrosine concentration in human plasma: persistence on low-protein diets. Science. 1967 Nov 3; 158(3801):660-2.
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Degroot LJ, Bransome ED, Stanbury JB, Wurtman RJ. Advances in endocrinology. Practitioner. 1967 Oct; 119(192):485-97.
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Wurtman RJ, Axelrod J, Chu EW, Heller A, Moore RY. Medial forebrain bundle lesions: blockade of effects of light on rat gonads and pineal. Endocrinology. 1967 Sep; 81(3):509-14.
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Wurtman RJ, Axelrod J, Sedvall G, Moore RY. Photic and neural control of the 24-hour norepinephrine rhythm in the rat pineal gland. J Pharmacol Exp Ther. 1967 Sep; 157(3):487-92.
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Wurtman RJ, Axelrod J, Tramezzani J. Distribution of the adrenaline-forming enzyme in the adrenal gland of a snake, Xenodon merremii. Nature. 1967 Aug 19; 215(5103):879-80.
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Wurtman RJ, Axelrod J. Daily rhythmic changes in tyrosine transaminase activity of the rat liver. Proc Natl Acad Sci U S A. 1967 Jun; 57(6):1594-8.
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Wurtman RJ, Noble EP, Axelrod J. Inhibition of enzymatic synthesis of epinephrine by low doses of glucocorticoids. Endocrinology. 1967 May; 80(5):825-8.
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Wurtman RJ. Ambiguities in the use of the term "circadian". Science. 1967 Apr 7; 156(3771):104.
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Shein HM, Wurtman RJ, Axelrod J. Synthesis of serotonin by pineal glands of the rat in organ culture. Nature. 1967 Feb 18; 213(5077):730-1.
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Noble EP, Wurtman RJ, Axelrod J. A simple and rapid method for injecting H3-norepinephrine into the lateral ventricle of the rat brain. Life Sci. 1967 Feb 1; 6(3):281-91.
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Moore RY, Heller A, Wurtman RJ, Axelrod J. Visual pathway mediating pineal response to environmental light. Science. 1967 Jan 13; 155(3759):220-3.
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Wurtman RJ. Latin american symposium on catecholamines. Science. 1966 Nov 4; 154(3749):680-1.
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Wurtman RJ, Axelrod J. Effect of chlorpromazine and other drugs on the disposition of circulating melatonin. Nature. 1966 Oct 15; 212(5059):312.
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Wells SA, Wurtman RJ, Rabson AS. Viral neoplastic transformation of hamster pineal cells in vitro: retention of enzymatic function. Science. 1966 Oct 14; 154(3746):278-9.
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Wurtman RJ. Control of epinephrine synthesis in the adrenal medulla by the adrenal cortex: hormonal specificity and dose-response characteristics. Endocrinology. 1966 Sep; 79(3):608-14.
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Wurtman RJ, Kammer H. Melatonin synthesis by an ectopic pinealoma. N Engl J Med. 1966 Jun 2; 274(22):1233-7.
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Snyder SH, Axelrod J, Wurtman RJ. Effect of gonadal hormones on aromatic amino acid decarboxylase in the rat uterus. Endocrinology. 1966 Jun; 78(6):1135-8.
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Wurtman RJ, Axelrod J. Control of enzymatic synthesis of adrenaline in the adrenal medulla by adrenal cortical steroids. J Biol Chem. 1966 May 25; 241(10):2301-5.
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Wurtman RJ, Axelrod J. A 24-hour rhythm in the content of norepinephrine in the pineal and salivary glands of the rat. Life Sci. 1966 Apr; 5(7):665-9.
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Wurtman RJ, Axelrod J. The physiologic effects of melatonin and the control of its biosynthesis. Probl Actuels Endocrinol Nutr. 1966; 10:189-200.
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Wurtman RJ, Axelrod J. The effect of thyroid and estrogen on the fate of catecholamines. Res Publ Assoc Res Nerv Ment Dis. 1966; 43:354-65.
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Axelrod J, Wurtman RJ. The pineal gland: a biological clock. Probl Actuels Endocrinol Nutr. 1966; 10:201-12.
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Wurtman RJ. Control of epinephrine synthesis by the pituitary and adrenal cortex: possible role in the pathophysiology of chronic stress. Recent Adv Biol Psychiatry. 1966; 9:359-68.
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Axelrod J, Wurtman RJ. The formation, metabolism and some actions of melatonin, a pineal gland substance. Res Publ Assoc Res Nerv Ment Dis. 1966; 43:200-11.
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Thoa NB, Wurtman RJ, Axelrod J. A deficient binding mechanism for norepinephrine in hearts of scorbutic guinea pigs. Proc Soc Exp Biol Med. 1966 Jan; 121(1):267-70.
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Wurtman RJ, Axelrod J. Adrenaline synthesis: control by the pituitary gland and adrenal glucocorticoids. Science. 1965 Dec 10; 150(3702):1464-5.
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Wurtman RJ. Catecholamines. N Engl J Med. 1965 Sep 30; 273(14):746-53 concl.
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Wurtman RJ. Catecholamines. N Engl J Med. 1965 Sep 23; 273(13):693-700 contd.
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Wurtman RJ. Catecholamines. N Engl J Med. 1965 Sep 16; 273(12):637-46 contd.
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WURTMAN RJ, AXELROD J. THE PINEAL GLAND. Sci Am. 1965 Jul; 213:50-60.
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WURTMAN RJ, AXELROD J, SNYDER SH, CHU EW. CHANGES IN THE ENZYMATIC SYNTHESIS OF METABOLISM IN THE PINEAL DURING THE ESTROUS CYCLE. Endocrinology. 1965 Apr; 76:798-800.
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SNYDER SH, AXELROD J, WURTMAN RJ, FISCHER JE. CONTROL OF 5-HYDROXYTRYPTOPHAN DECARBOXYLASE ACTIVITY IN THE RAT PINEAL GLAND BY SYMPATHETIC NERVES. J Pharmacol Exp Ther. 1965 Mar; 147:371-5.
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AXELROD J, WURTMAN RJ, SNYDER SH. CONTROL OF HYDROXYINDOLE O-METHYLTRANSFERASE ACTIVITY IN THE RAT PINEAL GLAND BY ENVIRONMENTAL LIGHTING. J Biol Chem. 1965 Feb; 240:949-54.
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WURTMAN RJ, AXELROD J. THE FORMATION, METABOLISM, AND PHYSIOLOGIC EFFECTS OF MELATONIN IN MAMMALS. Prog Brain Res. 1965; 10:520-9.
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WURTMAN RJ, AXELROD J. DEMONSTRATION OF HYDROXYINDOLE-O-METHYL TRANSFERASE, MELATONIN, AND SEROTONIN IN A METASTATIC PARENCHYMATOUS PINEALOMA. Nature. 1964 Dec 26; 204:1323-4.
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WURTMAN RJ. AN EFFECT OF LUTEINIZING HORMONE ON THE FRACTIONAL PERFUSION OF THE RAT OVARY. Endocrinology. 1964 Dec; 75:927-33.
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WURTMAN RJ, KOPIN IJ, HORST D, FISCHER JE. EPINEPHRINE AND ORGAN BLOOD FLOW: EFFECTS OF HYPERTHYROIDISM, COCAINE, AND DENERVATION. Am J Physiol. 1964 Dec; 207:1247-50.
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COHEN RA, WURTMAN RJ, AXELROD J, SNYDER SH. SOME CLINICAL, BIOCHEMICAL, AND PHYSIOLOGICAL ACTIONS OF THE PINEAL GLAND. COMBINED CLINICAL STAFF CONFERENCE AT THE NATIONAL INSTITUTES OF HEALTH. Ann Intern Med. 1964 Dec; 61:1144-61.
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SNYDER SH, WURTMAN RJ, AXELROD J, CHU EW. THE PHYSIOLOGICAL DISPOSITION OF C14-SEROTONIN IN THE RAT UTERUS. J Pharmacol Exp Ther. 1964 Dec; 146:276-9.
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GLOWINSKI J, AXELROD J, KOPIN IJ, WURTMAN RJ. PHYSIOLOGICAL DISPOSITION OF H3-NOREPINEPHRINE IN THE DEVELOPING RAT. J Pharmacol Exp Ther. 1964 Oct; 146:48-53.
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WURTMAN RJ, AXELROD J, CHU EW. THE RELATION BETWEEN MELATONIN, A PINEAL SUBSTANCE, AND THE EFFECTS OF LIGHT ON THE RAT GONAD. Ann N Y Acad Sci. 1964 Sep 10; 117:228-30.
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FISCHER JE, KOPIN IJ, WURTMAN RJ. EFFECTS OF LUMBAR SYMPATHECTOMY ON THE UTERINE UPTAKE OF CATECHOLAMINES. Nature. 1964 Aug 29; 203:938-9.
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SNYDER SH, AXELROD J, FISCHER JE, WURTMAN RJ. NEURAL AND PHOTIC REGULATION OF 5-HYDROXYTRYPTOPHAN DECARBOXYLASE IN THE RAT PINEAL GLAND. Nature. 1964 Aug 29; 203:981-2.
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WURTMAN RJ, AXELROD J, CHU EW, FISCHER JE. MEDIATION OF SOME EFFECT OF ILLUMINATION ON THE RAT ESTROUS CYCLE BY THE SYMPATHETIC NERVOUS SYSTEM. Endocrinology. 1964 Aug; 75:266-72.
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CHU EW, WURTMAN RJ, AXELROD J. AN INHIBITORY EFFECT OF MELATONIN ON THE ESTROUS PHASE OF THE ESTROUS CYCLE OF THE RODENT. Endocrinology. 1964 Aug; 75:238-42.
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GOLDMAN H, WURTMAN RJ. FLOW OF BLOOD TO THE PINEAL BODY OF THE RAT. Nature. 1964 Jul 4; 203:87-8.
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ZACHARIAS L, WURTMAN RJ. BLINDNESS: ITS RELATION TO AGE OF MENARCHE. Science. 1964 May 29; 144(3622):1154-5.
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WURTMAN RJ, AXELROD J, POTTER LT. THE DISPOSITION OF CATECHOLAMINES IN THE RAT UTERUS AND THE EFFECT OF DRUGS AND HORMONES. J Pharmacol Exp Ther. 1964 May; 144:150-5.
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WURTMAN RJ, AXELROD J, FISCHER JE. MELATONIN SYNTHESIS IN THE PINEAL GLAND: EFFECT OF LIGHT MEDIATED BY THE SYMPATHETIC NERVOUS SYSTEM. Science. 1964 Mar 20; 143(3612):1328-30.
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Wurtman RJ, Axelrod J, Fischer JE. Melatonin Synthesis in the Pineal Gland: Effect of Light Mediated by the Sympathetic Nervous System. Science. 1964 Mar 20; 143(3612):1328-9.
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AXELROD J, WURTMAN RJ, WINGET CM. MELATONIN SYNTHESIS IN THE HEN PINEAL GLAND AND ITS CONTROL BY LIGHT. Nature. 1964 Mar 14; 201:1134.
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WURTMAN RJ, AXELROD J, BARCHAS JD. AGE AND ENZYME ACTIVITY IN THE HUMAN PINEAL. J Clin Endocrinol Metab. 1964 Mar; 24:299-301.
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WURTMAN RJ, AXELROD J, POTTER LT. THE UPTAKE OF H3-MELATONIN IN ENDOCRINE AND NERVOUS TISSUES AND THE EFFECTS OF CONSTANT LIGHT EXPOSURE. J Pharmacol Exp Ther. 1964 Mar; 143:314-8.
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WURTMAN RJ, AXELROD J. A SENSITIVE AND SPECIFIC ASSAY FOR THE ESTIMATION OF MONOAMINE OXIDASE. Biochem Pharmacol. 1963 Dec; 12:1439-41.
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WURTMAN RJ, AXELROD J. SEX STEROIDS, CARDIAC 3H-NOREPINEPHRINE, AND TISSUE MONOAMINE OXIDASE LEVELS IN THE RAT. Biochem Pharmacol. 1963 Dec; 12:1417-9.
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WURTMAN RJ, AXELROD J, PHILLIPS LS. MELATONIN SYNTHESIS IN THE PINEAL GLAND: CONTROL BY LIGHT. Science. 1963 Nov 22; 142(3595):1071-3.
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WURTMAN RJ, AXELROD J, KOPIN IJ. UTERINE EPINEPHRINE AND BLOOD FLOW IN PREGNANT AND POSTPARTURIENT RATS. Endocrinology. 1963 Oct; 73:501-3.
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KOPIN IJ, WURTMAN RJ. FLOW OF UTERINE BLOOD, AND THE OESTROUS CYCLE. Nature. 1963 Jul 27; 199:386-7.
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WURTMAN RJ, AXELROD J, CHU EW. Melatonin, a pineal substance: effect on the rat ovary. Science. 1963 Jul 19; 141(3577):277-8.
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WURTMAN RJ, KOPIN IJ, AXELROD J. Thyroid function and the cardiac disposition of catecholamines. Endocrinology. 1963 Jul; 73:63-74.
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WURTMAN RJ, CHU EW, AXELROD J. Relation between the oestrous cycle and the binding of catecholamines in the rat uterus. Nature. 1963 May 11; 198:547-8.
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Axelrod J, Wurtman RJ, Chu EW. Effects of Melatonin, a Pineal Substance, on the Rat Ovary. Science. 1963 Apr 26; 140(3565):378.
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ROTH WD, WURTMAN RJ, ALTSCHULE MD. Morphologic changes in the pineal parenchyma cells of rats exposed to continuous light or darkness. Endocrinology. 1962 Dec; 71:888-92.
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MEYER CJ, WURTMAN RJ, ALTSCHULE MD, LAZO-WASEM EA. The arrest of prolonged estrus in "middle-aged" rats by pineal gland extract. Endocrinology. 1961 May; 68:795-800.
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WURTMAN RJ, ROTH W, ALTSCHULE MD, WURTMAN JJ. Interactions of the pineal and exposure to continuous light on organ weights of female rats. Acta Endocrinol (Copenh). 1961 Apr; 36:617-24.
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WURTMAN RJ, ALTSCHULE MD, GREEP RO, FALK JL, GRAVE G. The pineal gland and aldosterone. Am J Physiol. 1960 Dec; 199:1109-11.
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HOLMGREN U, ALTSCHULE MD, WURTMAN RJ. Effects of injection of bovine pineal extract on the nuclei of rat pineal parenchymal cells. Nature. 1960 Apr 30; 186:393-4.
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WURTMAN RJ, FRANK MM, MORSE WH, DEWS PB. Studies on behavior. V. Actions of l-epinephrine and related compounds. J Pharmacol Exp Ther. 1959 Dec; 127:281-7.
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WURTMAN RJ, ALTSCHULE MD, HOLMGREN U. Effects of pinealectomy and of a bovine pineal extract in rats. Am J Physiol. 1959 Jul; 197(1):108-10.
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WURTMAN RJ, FRANK MM, ALTSCHULE MD. The oxidative activity of blood serum in schizophrenic and manic-depressive psychoses. AMA Arch Intern Med. 1958 Nov; 102(5):790-4.
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FRANK MM, WURTMAN RJ. Some sources of error in the Akerfeldt test for serum oxidative activity. Proc Soc Exp Biol Med. 1958 Feb; 97(2):478-80.