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Institution

Masako Shimada, PH.D., M.D.

TitleAssistant Professor of Medicine
InstitutionMassachusetts General Hospital
DepartmentMedicine
AddressMassachusetts General Hospital
Endocrine, THR 10
50 Blossom St
Boston MA 02114
Phone617/726-6726
Fax617/726-1703

 Bibliographic 
 selected publications
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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  1. Shimada M. microRNA-mediated Regulation of Apoptosis in Osteosarcoma. J. Carcinogene. Mutagene. (DOI 10.4172/2157-2518.S6-001). 2013; (S6).
  2. Shimada M. Calpain-Mediated Regulation of Bone and Fat Mass and Glucose Homeostasis in Osteoblasts. In Adipocytes: Biology, Regulation and Health Impact (Cell Biology Series), NOVA Science Publishers Inc. Hauppauge, NY. 2013; 133-143.
  3. Naka A, Iida KT, Nakagawa Y, Iwasaki H, Takeuchi Y, Satoh A, Matsuzaka T, Ishii KA, Kobayashi K, Yatoh S, Shimada M, Yahagi N, Suzuki H, Sone H, Yamada N, Shimano H. TFE3 inhibits myoblast differentiation in C2C12 cells via down-regulating gene expression of myogenin. Biochem Biophys Res Commun. 2013 Jan 11; 430(2):664-9.
    View in: PubMed
  4. Matsuzaka T, Atsumi A, Matsumori R, Nie T, Shinozaki H, Suzuki-Kemuriyama N, Kuba M, Nakagawa Y, Ishii K, Shimada M, Kobayashi K, Yatoh S, Takahashi A, Takekoshi K, Sone H, Yahagi N, Suzuki H, Murata S, Nakamuta M, Yamada N, Shimano H. Elovl6 promotes nonalcoholic steatohepatitis. Hepatology. 2012 Dec; 56(6):2199-208.
    View in: PubMed
  5. Shimada M. Overview of Calpain-Mediated Regulation of Bone and Fat Mass in Osteoblasts. Cell Biochem Biophys. 2012 Jul 21.
    View in: PubMed
  6. Kashiwagi A, Fein MJ, Shimada M. Calpain modulates cyclin-dependent kinase inhibitor 1B (p27(Kip1)) in cells of the osteoblast lineage. Calcif Tissue Int. 2011 Jul; 89(1):36-42.
    View in: PubMed
  7. Kashiwagi A, Fein MJ, Shimada M. A high fat diet-induced impaired glucose metabolism in mice with targeted deletion of calpain in osteoblasts. Biochem Biophys Res Commun. 2011 Jun 3; 409(2):235-40.
    View in: PubMed
  8. Kashiwagi A, Schipani E, Fein MJ, Greer PA, Shimada M. Targeted deletion of Capn4 in cells of the chondrocyte lineage impairs chondrocyte proliferation and differentiation. Mol Cell Biol. 2010 Jun; 30(11):2799-810.
    View in: PubMed
  9. Shimada M. A challenging case of severe acute hypertriglyceridemia-induced pancreatitis. South Med J. 2009 Oct; 102(10):999-1000.
    View in: PubMed
  10. Shimada M, Greer PA, McMahon AP, Bouxsein ML, Schipani E. In vivo targeted deletion of calpain small subunit, Capn4, in cells of the osteoblast lineage impairs cell proliferation, differentiation, and bone formation. J Biol Chem. 2008 Jul 25; 283(30):21002-10.
    View in: PubMed
  11. Murase T, Okubo M, Amemiya-Kudo M, Hiraga T, Oka J, Shimada M, Igarashi T. Impact of markedly elevated serum lipoprotein(a) levels (> or = 100 mg/dL) on the risk of coronary heart disease. Metabolism. 2007 Sep; 56(9):1187-91.
    View in: PubMed
  12. Shimada M. MCH knockout mice. The Lipid. 2006; 17(4):4-10.
  13. Shimada M, Mahon MJ, Greer PA, Segre GV. The receptor for parathyroid hormone and parathyroid hormone-related peptide is hydrolyzed and its signaling properties are altered by directly binding the calpain small subunit. Endocrinology. 2005 May; 146(5):2336-44.
    View in: PubMed
  14. Mahon MJ, Shimada M. Calmodulin interacts with the cytoplasmic tails of the parathyroid hormone 1 receptor and a sub-set of class b G-protein coupled receptors. FEBS Lett. 2005 Jan 31; 579(3):803-7.
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  15. Shimada M, Chen X, Cvrk T, Hilfiker H, Parfenova M, Segre GV. Purification and characterization of a receptor for human parathyroid hormone and parathyroid hormone-related peptide. J Biol Chem. 2002 Aug 30; 277(35):31774-80.
    View in: PubMed
  16. Shimada M. Role of melanin concentrating hormone in obesity. The latest medicine. 2001; 56:121-128.
  17. Shimada M. Molecular mechanism of obesity in the central nervous system. Endocrinology and Metabolism. 2001; 1-7.
  18. Shimada M. Mice lacking melanin concentrating hormone and obesity. J. Japan Society for the Study of Obesity. 2001; 75:57-58.
  19. Yagyu H, Ishibashi S, Chen Z, Osuga J, Okazaki M, Perrey S, Kitamine T, Shimada M, Ohashi K, Harada K, Shionoiri F, Yahagi N, Gotoda T, Yazaki Y, Yamada N. Overexpressed lipoprotein lipase protects against atherosclerosis in apolipoprotein E knockout mice. J Lipid Res. 1999 Sep; 40(9):1677-85.
    View in: PubMed
  20. Shimada M, Tritos NA, Lowell BB, Flier JS, Maratos-Flier E. Mice lacking melanin-concentrating hormone are hypophagic and lean. Nature. 1998 Dec 17; 396(6712):670-4.
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  21. Abe H, Yamada N, Kamata K, Kuwaki T, Shimada M, Osuga J, Shionoiri F, Yahagi N, Kadowaki T, Tamemoto H, Ishibashi S, Yazaki Y, Makuuchi M. Hypertension, hypertriglyceridemia, and impaired endothelium-dependent vascular relaxation in mice lacking insulin receptor substrate-1. J Clin Invest. 1998 Apr 15; 101(8):1784-8.
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  22. Gotoda T, Kinoshita M, Ishibashi S, Inaba T, Harada K, Shimada M, Osuga J, Teramoto T, Yazaki Y, Yamada N. Skipping of exon 14 and possible instability of both the mRNA and the resultant truncated protein underlie a common cholesteryl ester transfer protein deficiency in Japan. Arterioscler Thromb Vasc Biol. 1997 Jul; 17(7):1376-81.
    View in: PubMed
  23. Shimada M. Approach for atherosclerosis using genetic Engineering; Transgenic and Knockout Mice. Circulation Now. 1997; 12:42-47.
  24. Shimada M. Secondary hyperlipidemia. Medical Practice. 1997; 14(4):612-613.
  25. Ishibashi S, Shimada M, Chen Z, Yagyu H, Ohsuga J., Harada K, Inaba T, Ohashi K, Yamada N, Yazaki Y. Atherosclerosis in various transgenic models with altered lipoprotein metabolism. J. Japan Atherosclerosis Society. 1997; 24:477-480.
  26. Shimada M. Molecular Biology in Obesity; Adipsin and TNF-alpha. Hormone and Medicine. 1997; 45:59-64.
  27. Shimada M. Atherogenic lipoprotein; Remnant. Mebio. 1997; 14:48-53.
  28. Shimada M. Letter from abroad (Boston). The Lipid. 1997; 8(4):96-98.
  29. Shimada M. Hyper Lp (a). Diabetes Mellitus. 1997; 226-227.
  30. Hiraga T, Shimada M, Tsukada T, Murase T. Hypertriglyceridemia, but not hypercholesterolemia, is associated with the alterations of fibrinolytic system. Horm Metab Res. 1996 Nov; 28(11):603-6.
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  31. Ishibashi S, Perrey S, Chen Z, Osuga Ji, Shimada M, Ohashi K, Harada K, Yazaki Y, Yamada N. Role of the low density lipoprotein (LDL) receptor pathway in the metabolism of chylomicron remnants. A quantitative study in knockout mice lacking the LDL receptor, apolipoprotein E, or both. J Biol Chem. 1996 Sep 13; 271(37):22422-7.
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  32. Shimada M, Ishibashi S, Inaba T, Yagyu H, Harada K, Osuga JI, Ohashi K, Yazaki Y, Yamada N. Suppression of diet-induced atherosclerosis in low density lipoprotein receptor knockout mice overexpressing lipoprotein lipase. Proc Natl Acad Sci U S A. 1996 Jul 9; 93(14):7242-6.
    View in: PubMed
  33. Hiraga T, Shimada M, Okubo M, Nakanishi K, Kobayashi T, Murase T. Lipoprotein(a) is an independent risk factor for multiple cerebral infarctions. Atherosclerosis. 1996 Apr 26; 122(1):29-32.
    View in: PubMed
  34. Shimada M, Yamada N. . Knockout mice (ApoE). Manual of Medical experiments; Strategy in studies of atherosclerosis and hyperlipidemia. 1996; 441-443.
  35. Teramoto, T., Yamada, N., Shimada, M., Oka, T., Itakura, H., Saito, Y., Morisaki, N., Shirai, A., Ishikawa, Toda, Ito, Yamaguchi, Matsushima, Kawakami, M., Murase, T., Ohkubo, M., Totsuka, and Kiuchi . Dose dependent effects of niceritrol on plasma lipoprotein (a). Sacnd. J. Lab. Invest. 1996; 56:359-365.
  36. Shimada M, Yamada N. . IGT and coronary atherosclerosis. Medicine. 1996; 33:310-312.
  37. Shimada M, Ishibashi S, Gotoda T, Kawamura M, Yamamoto K, Inaba T, Harada K, Ohsuga J, Perrey S, Yazaki Y, et al. Overexpression of human lipoprotein lipase protects diabetic transgenic mice from diabetic hypertriglyceridemia and hypercholesterolemia. Arterioscler Thromb Vasc Biol. 1995 Oct; 15(10):1688-94.
    View in: PubMed
  38. Osuga J, Inaba T, Harada K, Yagyu H, Shimada M, Yazaki Y, Yamada N, Ishibashi S. Cloning and structural analysis of the mouse apolipoprotein B mRNA editing protein gene. Biochem Biophys Res Commun. 1995 Sep 14; 214(2):653-62.
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  39. Shimada M, Ishibashi S, Yamamoto K, Kawamura M, Watanabe Y, Gotoda T, Harada K, Inaba T, Ohsuga J, Yazaki Y, et al. Overexpression of human lipoprotein lipase increases hormone-sensitive lipase activity in adipose tissue of mice. Biochem Biophys Res Commun. 1995 Jun 26; 211(3):761-6.
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  40. Yamamoto K, Shimano H, Shimada M, Kawamura M, Gotoda T, Harada K, Ohsuga J, Yazaki Y, Yamada N. Overexpression of apolipoprotein E prevents development of diabetic hyperlipidemia in transgenic mice. Diabetes. 1995 May; 44(5):580-5.
    View in: PubMed
  41. Inaba T, Kawamura M, Gotoda T, Harada K, Shimada M, Ohsuga J, Shimano H, Akanuma Y, Yazaki Y, Yamada N. Effects of platelet-derived growth factor on the synthesis of lipoprotein lipase in human monocyte-derived macrophages. Arterioscler Thromb Vasc Biol. 1995 Apr; 15(4):522-8.
    View in: PubMed
  42. Inaba T, Gotoda T, Harada K, Shimada M, Ohsuga J, Ishibashi S, Yazaki Y, Yamada N. Induction of sustained expression of proto-oncogene c-fms by platelet-derived growth factor, epidermal growth factor, and basic fibroblast growth factor, and its suppression by interferon-gamma and macrophage colony-stimulating factor in human aortic medial smooth muscle cells. J Clin Invest. 1995 Mar; 95(3):1133-9.
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  43. Shimano H, Ohsuga J, Shimada M, Namba Y, Gotoda T, Harada K, Katsuki M, Yazaki Y, Yamada N. Inhibition of diet-induced atheroma formation in transgenic mice expressing apolipoprotein E in the arterial wall. J Clin Invest. 1995 Feb; 95(2):469-76.
    View in: PubMed
  44. Watanabe Y, Inaba T, Gotoda T, Harada K, Shimada M, Ohsuga J, Kawamura M, Yazaki Y, Yamada N. Role of macrophage colony-stimulating factor in the initial process of atherosclerosis. Ann N Y Acad Sci. 1995 Jan 17; 748:357-64; discussion 364-6.
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  45. Shimada M, Yamada N. Transgenic mice. Medical Practice. 1995; 12:971-973.
  46. Shimada M, Murase T. . Sex steroid and lipid metabolism. Endocrinology and Diabetes Mellitus. 1995; 12:587-192.
  47. Shimada M, Yamada N. . Transgenic mice overexpressing lipoprotein lipase. The Lipid. 1995; 6:40-46.
  48. Shimada M, Yamada N. . Transgenic mice. J. Japan Obesity Society. 1995; 6-7.
  49. Inaba, T., Gotoda, T., Ishibashi, S., Harada, K., Shimada, M., Ohsuga, J. and Yamada, N. Involvement of Transcription Factor PU.1 in Phenotypic Transformation of Vascular Smooth Muscle Cells to Macrophage-like Cells. Circulation. 1995; Supplement I(92(4), Part 2):I-359 (1709).
  50. Shimada M, Ishibashi S, Inaba T, Yaguy H, Harada K, Ohsuga J, Yazaki Y . Overexpression of Lipoprotein Lipase Reduced Atherosclerotic Lesions in Low Density Lipoprotein Receptor Deficient Mice. Circulation. 1995; Supplement I(92(4), Part 2):I-359 (1709).
  51. Inaba, T., Yamada, N., Ishibashi, S., Gotoda, T., Harada, K., Shimada, M., Ohsuga, J. and Yazaki, Y. Expression and effect of PDGF-b receptor in monocyte-derived macrophages. Japanese Society of Clinical Metabolism. 1995; 31:54-55.
  52. Shimada M, Yamada N. . Lipoprotein Lipase. J. Japan Atherosclerosis Society. 1995; 23:243-247.
  53. Shimada M, Yamada N. The mechanism of obesity; the study of obesity using transgenic mice. Internal Medicine. 1995; 75:648-651.
  54. Yamamoto K, Shimano H, Inaba T, Gotoda T, Harada K, Shimada M, Watanabe Y, Osuga J, Kawamura M, Yazaki Y, et al. Regulation of low density lipoprotein receptor activity in Chinese hamster ovary cells transfected with the c-fms gene. FEBS Lett. 1994 Dec 12; 356(1):72-5.
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  55. Yamada N, Yoshinaga H, Gotoda T, Harada K, Shimada M, Ohsuga J, Akanuma Y, Murase T. Plasma lipid abnormalities and risk factors for coronary artery disease in Japanese subjects with diabetes mellitus and glucose intolerance. Diabetes Res Clin Pract. 1994 Oct; 24 Suppl:S215-20.
    View in: PubMed
  56. Kawamura M, Gotoda T, Mori N, Shimano H, Kozaki K, Harada K, Shimada M, Inaba T, Watanabe Y, Yazaki Y, et al. Establishment of enzyme-linked immunosorbent assays for lipoprotein lipase with newly developed antibodies. J Lipid Res. 1994 Sep; 35(9):1688-97.
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  57. Shimada M. Lipid metabolism in mice overexpressing human lipoprotein lipase. 1994.
  58. Shimano H, Namba Y, Ohsuga J, Kawamura M, Yamamoto K, Shimada M, Gotoda T, Harada K, Yazaki Y, Yamada N. Secretion-recapture process of apolipoprotein E in hepatic uptake of chylomicron remnants in transgenic mice. J Clin Invest. 1994 May; 93(5):2215-23.
    View in: PubMed
  59. Shimano H, Namba Y, Ohsuga J, Yamamoto K, Shimada M, Gotoda T, Harada K, Yazaki Y, Yamada N. Metabolism of chylomicron remnants in transgenic mice expressing apolipoprotein E in the intestine. Biochem Biophys Res Commun. 1994 Apr 29; 200(2):716-21.
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  60. Tsubamoto Y, Yamada N, Watanabe Y, Inaba T, Shiomi M, Shimano H, Gotoda T, Harada K, Shimada M, Ohsuga J, et al. Dextran sulfate, a competitive inhibitor for scavenger receptor, prevents the progression of atherosclerosis in Watanabe heritable hyperlipidemic rabbits. Atherosclerosis. 1994 Mar; 106(1):43-50.
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  61. Shimano H, Takahashi K, Kawakami M, Gotoda T, Harada K, Shimada M, Yazaki Y, Yamada N. Elevated serum and urinary thrombomodulin levels in patients with non-insulin-dependent diabetes mellitus. Clin Chim Acta. 1994 Mar; 225(2):89-96.
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  62. Kawamura M, Shimano H, Gotoda T, Harada K, Shimada M, Ohsuga J, Inaba T, Watanabe Y, Yamamoto K, Kozaki K, et al. Overexpression of human lipoprotein lipase enhances uptake of lipoproteins containing apolipoprotein B-100 in transfected cells. Arterioscler Thromb. 1994 Feb; 14(2):235-42.
    View in: PubMed
  63. Yamada N, Inaba T, Kawamura M, Gotoda T, Shimano H, Harada K, Shimada M, Ogsuga J, Ishibashi S. Effects of platelet-derived growth factor on the synthesis of lipoprotein lipase in human monocyte-derived macrophages. Circulation. 1994; Supplement I(90(4), Part 2):I-404 (2166).
  64. Shimada M, Gotoda T, Yamada N. . Lipoprotein Lipase. Medicine. 1994; 31:190-192.
  65. Inaba T, Shimano H, Gotoda T, Harada K, Shimada M, Ohsuga J, Watanabe Y, Kawamura M, Yazaki Y, Yamada N, et al. Expression of platelet-derived growth factor beta receptor on human monocyte-derived macrophages and effects of platelet-derived growth factor BB dimer on the cellular function. J Biol Chem. 1993 Nov 15; 268(32):24353-60.
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  66. Shimada M, Shimano H, Gotoda T, Yamamoto K, Kawamura M, Inaba T, Yazaki Y, Yamada N. Overexpression of human lipoprotein lipase in transgenic mice. Resistance to diet-induced hypertriglyceridemia and hypercholesterolemia. J Biol Chem. 1993 Aug 25; 268(24):17924-9.
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  67. Inaba T, Shimano H, Gotoda T, Harada K, Shimada M, Kawamura M, Yazaki Y, Yamada N. Macrophage colony-stimulating factor regulates both activities of neutral and acidic cholesteryl ester hydrolases in human monocyte-derived macrophages. J Clin Invest. 1993 Aug; 92(2):750-7.
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  68. Gotoda T, Kinoshita M, Shimano H, Harada K, Shimada M, Ohsuga J, Teramoto T, Yazaki Y, Yamada N. Cholesteryl ester transfer protein deficiency caused by a nonsense mutation detected in the patient's macrophage mRNA. Biochem Biophys Res Commun. 1993 Jul 15; 194(1):519-24.
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  69. Watanabe Y, Inoue I, Inaba T, Shimano H, Gotoda T, Harada K, Shimada M, Kawazu S, Komeda K, Yazaki Y, et al. Effect of macrophage colony-stimulating factor on the development of diabetes mellitus in BB rats. Horm Metab Res. 1993 Jun; 25(6):323-4.
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  70. Ishibashi S, Mori N, Shimada M, Oka T, Shimano H, Gotoda T, Komeda K, Kawazu S, Murase T, Yazaki Y, et al. Apolipoprotein E metabolism in sciatic nerves of diabetic rats. Implication for diabetic neuropathy. Horm Metab Res. 1993 Feb; 25(2):82-7.
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  71. Shimano H, Shimada M, Gotoda T, Harada K, Yamada N. Secretion Recapture Process of Apolipoprotein E in Hepatic Uptake of Chyromicron Remnants in Transgenic Mice. Circulation. 1993; Supplement I(88(4), Part2):I-2 (7).
  72. Shimano H, Yamada N, Ohsuga J, Shimada M, Yazaki Y. Anti-atherogenic Effect of Apolipoprotein E is Mediated through Enhanced Cholesterol Efflux in Transgenic Mice. Circulation. 1993; Supplement I(88(4), Part 2):I-421 (2264).
  73. Shimada, M., Yamada, N., Shimano, H., Gotoda, T., Yamamoto, K., Kawamura, M., Inaba, T. and Yazaki, Y. Overexpression of Human Lipoprotein Lipase in Transgenic Mice. Circulation. 1993; Supplement I(88(4), Part 2):I-179 (952).
  74. Inaba T, Shimano H, Gotoda T, Harada K, Shimada M, Ohsuga J, Watanaba Y, Kawamura M, Yamada N. Regulation of both activities of neural and acidic cholesteryl ester hydrolases by acetyl-LDL in human monocyte-derived macrophages. Circulation. 1993; Supplement I(88(4)):I-227 (1213).
  75. Shimano H, Yamada N, Katsuki M, Yamamoto K, Gotoda T, Harada K, Shimada M, Yazaki Y. Plasma lipoprotein metabolism in transgenic mice overexpressing apolipoprotein E. Accelerated clearance of lipoproteins containing apolipoprotein B. J Clin Invest. 1992 Nov; 90(5):2084-91.
    View in: PubMed
  76. Shimada M, Inaba T, Shimano H, Gotoda T, Watanabe Y, Yamamoto K, Motoyoshi K, Yazaki Y, Yamada N. Platelet-derived growth factor BB-dimer suppresses the expression of macrophage colony-stimulating factor in human vascular smooth muscle cells. J Biol Chem. 1992 Aug 5; 267(22):15455-8.
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  77. Gotoda T, Yamada N, Murase T, Shimano H, Shimada M, Harada K, Kawamura M, Kozaki K, Yazaki Y. Detection of three separate DNA polymorphisms in the human lipoprotein lipase gene by gene amplification and restriction endonuclease digestion. J Lipid Res. 1992 Jul; 33(7):1067-72.
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  78. Inaba T, Gotoda T, Shimano H, Shimada M, Harada K, Kozaki K, Watanabe Y, Hoh E, Motoyoshi K, Yazaki Y, et al. Platelet-derived growth factor induces c-fms and scavenger receptor genes in vascular smooth muscle cells. J Biol Chem. 1992 Jun 25; 267(18):13107-12.
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  79. Yamada N, Ishibashi S, Shimano H, Inaba T, Gotoda T, Harada K, Shimada M, Shiomi M, Watanabe Y, Kawakami M, et al. Role of monocyte colony-stimulating factor in foam cell generation. Proc Soc Exp Biol Med. 1992 Jun; 200(2):240-4.
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  80. Gotoda T, Yamada N, Murase T, Miyake S, Murakami R, Kawamura M, Kozaki K, Mori N, Shimano H, Shimada M, et al. A newly identified null allelic mutation in the human lipoprotein lipase (LPL) gene of a compound heterozygote with familial LPL deficiency. Biochim Biophys Acta. 1992 Apr 14; 1138(4):353-6.
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  81. Inaba T, Yamada N, Gotoda T, Shimano H, Shimada M, Momomura K, Kadowaki T, Motoyoshi K, Tsukada T, Morisaki N, et al. Expression of M-CSF receptor encoded by c-fms on smooth muscle cells derived from arteriosclerotic lesion. J Biol Chem. 1992 Mar 15; 267(8):5693-9.
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  82. Shimano H, Yamada N, Katsuki M, Shimada M, Gotoda T, Harada K, Murase T, Fukazawa C, Takaku F, Yazaki Y. Overexpression of apolipoprotein E in transgenic mice: marked reduction in plasma lipoproteins except high density lipoprotein and resistance against diet-induced hypercholesterolemia. Proc Natl Acad Sci U S A. 1992 Mar 1; 89(5):1750-4.
    View in: PubMed
  83. Yamada N, Inoue I, Kawamura M, Harada K, Watanabe Y, Shimano H, Gotoda T, Shimada M, Kohzaki K, Tsukada T, et al. Apolipoprotein E prevents the progression of atherosclerosis in Watanabe heritable hyperlipidemic rabbits. J Clin Invest. 1992 Feb; 89(2):706-11.
    View in: PubMed
  84. Shimano H, Yamada N, Katsuki M, Shimada M, Gotoda, T, Yazaki Y. Plasma Lipoprotein Metabolism in Apolipoprotein E Transgenic Mice. Circulation. 1992; Supplement I(86(4)):I-278 (1105).
  85. Shimano H, Fukazawa C, Shibasaki Y, Mori N, Gotoda T, Harada K, Shimada M, Yamada N, Yazaki Y, Takaku F. The effect of apo E secretion on lipoprotein uptake in transfected cells. Biochim Biophys Acta. 1991 Nov 27; 1086(3):245-54.
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  86. Inoue I, Ishibashi S, Harada K, Shimano H, Gotoda T, Shimada M, Takahashi K, Ishii J, Yazaki Y, Yamada N. Overexpression of low density lipoprotein receptor on Chinese hamster ovary cells generates foam cells. Arterioscler Thromb. 1991 Sep-Oct; 11(5):1310-4.
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  87. Shimano H, Yamada N, Shimada M, Ohsawa N, Fukazawa C, Yazaki Y, Takaku F, Katsuki M. Hepatic and renal expression of rat apolipoprotein E under control of the metallothionein promoter in transgenic mice. Biochim Biophys Acta. 1991 Aug 27; 1090(1):91-4.
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  88. Takahashi K, Shimada M. . LDL receptor related protein. Current Medicine. 1991; 23:97-100.
  89. Shimada M, Takahashi K Yamada N. . The structure and function of LRP. The Lipid. 1991; 2:168-180.
  90. Shimada M, Takagi A, Ida M, Kojima S, Shiozawa R, Araki M, Shimizu H, Takahashi M. Exertion-induced heat stroke in a patient with asymptomatic neurogenic muscular atorophy. Anesthesia and Resuscitation. 1989; 25:65-69.
  91. Ishibashi S, Yamada N, Oka Y, Shimano H, Mori N, Yoon TH, Shimada M, Kanazawa Y, Akanuma Y, Murase T, et al. Enhanced synthesis and secretion of apolipoprotein E from sciatic nerves of streptozotocin-induced diabetic rats after injury. Biochem Biophys Res Commun. 1988 Aug 30; 155(1):283-8.
    View in: PubMed
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