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Michelle Connolly Specht, M.D.

TitleAssistant Professor of Surgery
InstitutionMassachusetts General Hospital
DepartmentSurgery
AddressMassachusetts General Hospital
Surgery, COX 6
55 Fruit St
Boston MA 02114
Phone617/726-8555

 Mentoring 
 completed student projects
A Nomogram for Predicting Successful Re-Excision in Breast Cancer Patients with Close or Positive Margins
Part Time, 06/23/08 - 08/08/08

 Bibliographic 
 selected publications
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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  1. Hedegard W, Niell B, Specht M, Winograd J, Rafferty E. Breast reconstruction with a deep inferior epigastric perforator flap: imaging appearances of the normal flap and common complications. AJR Am J Roentgenol. 2013 Jan; 200(1):W75-84.
    View in: PubMed
  2. Coopey SB, Mazzola E, Buckley JM, Sharko J, Belli AK, Kim EM, Polubriaginof F, Parmigiani G, Garber JE, Smith BL, Gadd MA, Specht MC, Guidi AJ, Roche CA, Hughes KS. The role of chemoprevention in modifying the risk of breast cancer in women with atypical breast lesions. Breast Cancer Res Treat. 2012 Dec; 136(3):627-33.
    View in: PubMed
  3. Ancukiewicz M, Miller CL, Skolny MN, O'Toole J, Warren LE, Jammallo LS, Specht MC, Taghian AG. Erratum to: Comparison of relative versus absolute arm size change as criteria for quantifying breast cancer-related lymphedema: the flaws in current studies and need for universal methodology. Breast Cancer Res Treat. 2012 Nov; 136(2):623.
    View in: PubMed
  4. Coopey SB, Specht MC, Warren L, Smith BL, Winograd JM, Fleischmann K. Use of preoperative paravertebral block decreases length of stay in patients undergoing mastectomy plus immediate reconstruction. Ann Surg Oncol. 2013 Apr; 20(4):1282-6.
    View in: PubMed
  5. Niell B, Specht M, Gerade B, Rafferty E. Is excisional biopsy required after a breast core biopsy yields lobular neoplasia? AJR Am J Roentgenol. 2012 Oct; 199(4):929-35.
    View in: PubMed
  6. Camp MS, Greenup RA, Taghian A, Coopey SB, Specht M, Gadd M, Hughes K, Smith BL. Application of ACOSOG Z0011 Criteria Reduces Perioperative Costs. Ann Surg Oncol. 2013 Mar; 20(3):836-41.
    View in: PubMed
  7. Miller CL, Specht MC, Skolny MN, Jammallo LS, Horick N, O'Toole J, Coopey SB, Hughes K, Gadd M, Smith BL, Taghian AG. Sentinel lymph node biopsy at the time of mastectomy does not increase the risk of lymphedema: implications for prophylactic surgery. Breast Cancer Res Treat. 2012 Oct; 135(3):781-9.
    View in: PubMed
  8. Greenup RA, Camp MS, Taghian AG, Buckley J, Coopey SB, Gadd M, Hughes K, Specht M, Smith BL. Cost comparison of radiation treatment options after lumpectomy for breast cancer. Ann Surg Oncol. 2012 Oct; 19(10):3275-81.
    View in: PubMed
  9. Buckley JM, Coopey SB, Sharko J, Polubriaginof F, Drohan B, Belli AK, Kim EM, Garber JE, Smith BL, Gadd MA, Specht MC, Roche CA, Gudewicz TM, Hughes KS. The feasibility of using natural language processing to extract clinical information from breast pathology reports. J Pathol Inform. 2012; 3:23.
    View in: PubMed
  10. Ancukiewicz M, Miller CL, Skolny MN, O'Toole J, Warren LE, Jammallo LS, Specht MC, Taghian AG. Comparison of relative versus absolute arm size change as criteria for quantifying breast cancer-related lymphedema: the flaws in current studies and need for universal methodology. Breast Cancer Res Treat. 2012 Aug; 135(1):145-52.
    View in: PubMed
  11. Pashtan IM, Recht A, Ancukiewicz M, Brachtel E, Abi-Raad RF, D'Alessandro HA, Levy A, Wo JY, Hirsch AE, Kachnic LA, Goldberg S, Specht M, Gadd M, Smith BL, Powell SN, Taghian AG. External beam accelerated partial-breast irradiation using 32 gy in 8 twice-daily fractions: 5-year results of a prospective study. Int J Radiat Oncol Biol Phys. 2012 Nov 1; 84(3):e271-7.
    View in: PubMed
  12. Dominici LS, Lester S, Liao GS, Guo L, Specht M, Smith BL, Golshan M. Current surgical approach to Paget's disease. Am J Surg. 2012 Jul; 204(1):18-22.
    View in: PubMed
  13. Coopey SB, Buckley JM, Smith BL, Hughes KS, Gadd MA, Specht MC. Lumpectomy cavity shaved margins do not impact re-excision rates in breast cancer patients. Ann Surg Oncol. 2011 Oct; 18(11):3036-40.
    View in: PubMed
  14. Coopey S, Smith BL, Hanson S, Buckley J, Hughes KS, Gadd M, Specht MC. The safety of multiple re-excisions after lumpectomy for breast cancer. Ann Surg Oncol. 2011 Dec; 18(13):3797-801.
    View in: PubMed
  15. Ancukiewicz M, Russell TA, Otoole J, Specht M, Singer M, Kelada A, Murphy CD, Pogachar J, Gioioso V, Patel M, Skolny M, Smith BL, Taghian AG. Standardized method for quantification of developing lymphedema in patients treated for breast cancer. Int J Radiat Oncol Biol Phys. 2011 Apr 1; 79(5):1436-43.
    View in: PubMed
  16. Samphao S, Wheeler AJ, Rafferty E, Michaelson JS, Specht MC, Gadd MA, Hughes KS, Smith BL. Diagnosis of breast cancer in women age 40 and younger: delays in diagnosis result from underuse of genetic testing and breast imaging. Am J Surg. 2009 Oct; 198(4):538-43.
    View in: PubMed
  17. Javid SH, Kirstein LJ, Rafferty E, Lipsitz S, Moore R, Rusby JE, Murphy CD, Hughes KS, Specht MC, Taghian AG, Smith BL. Outcome of multiple-wire localization for larger breast cancers: do multiple wires translate into additional imaging, biopsies, and recurrences? Am J Surg. 2009 Sep; 198(3):368-72.
    View in: PubMed
  18. Murphy CD, Lee JM, Drohan B, Euhus DM, Kopans DB, Gadd MA, Rafferty EA, Specht MC, Smith BL, Hughes KS. The American Cancer Society guidelines for breast screening with magnetic resonance imaging: an argument for genetic testing. Cancer. 2008 Dec 1; 113(11):3116-20.
    View in: PubMed
  19. Pandharipande PV, Harisinghani MG, Ozanne EM, Specht MC, Hur C, Lee JM, Gazelle GS. Staging MR lymphangiography of the axilla for early breast cancer: cost-effectiveness analysis. AJR Am J Roentgenol. 2008 Nov; 191(5):1308-19.
    View in: PubMed
  20. Sakr Y, Krauss C, Amaral AC, Réa-Neto A, Specht M, Reinhart K, Marx G. Comparison of the performance of SAPS II, SAPS 3, APACHE II, and their customized prognostic models in a surgical intensive care unit. Br J Anaesth. 2008 Dec; 101(6):798-803.
    View in: PubMed
  21. Murphy CD, Jones JL, Javid SH, Michaelson JS, Nolan ME, Lipsitz SR, Specht MC, Lesnikoski BA, Hughes KS, Gadd MA, Smith BL. Do sentinel node micrometastases predict recurrence risk in ductal carcinoma in situ and ductal carcinoma in situ with microinvasion? Am J Surg. 2008 Oct; 196(4):566-8.
    View in: PubMed
  22. Kirstein LJ, Rafferty E, Specht MC, Moore RH, Taghian AG, Hughes KS, Gadd MA, Smith BL. Outcomes of multiple wire localization for larger breast cancers: when can mastectomy be avoided? J Am Coll Surg. 2008 Sep; 207(3):342-6.
    View in: PubMed
  23. Katz A, Smith BL, Golshan M, Niemierko A, Kobayashi W, Raad RA, Kelada A, Rizk L, Wong JS, Bellon JR, Gadd M, Specht M, Taghian AG. Nomogram for the prediction of having four or more involved nodes for sentinel lymph node-positive breast cancer. J Clin Oncol. 2008 May 1; 26(13):2093-8.
    View in: PubMed
  24. Miller JC, Rafferty EA, Specht MC, Thrall JH, Lee SI. When is breast magnetic resonance imaging recommended for cancer detection? J Am Coll Radiol. 2008 Mar; 5(3):224-6.
    View in: PubMed
  25. Dominguez FJ, Golshan M, Black DM, Hughes KS, Gadd MA, Christian R, Lesnikoski BA, Specht M, Michaelson J, Smith BL. Sentinel node biopsy is important in mastectomy for ductal carcinoma in situ. Ann Surg Oncol. 2008 Jan; 15(1):268-73.
    View in: PubMed
  26. Black D, Specht M, Lee JM, Dominguez F, Gadd M, Hughes K, Rafferty E, Smith B. Detecting occult malignancy in prophylactic mastectomy: preoperative MRI versus sentinel lymph node biopsy. Ann Surg Oncol. 2007 Sep; 14(9):2477-84.
    View in: PubMed
  27. Kozak KR, Smith BL, Adams J, Kornmehl E, Katz A, Gadd M, Specht M, Hughes K, Gioioso V, Lu HM, Braaten K, Recht A, Powell SN, DeLaney TF, Taghian AG. Accelerated partial-breast irradiation using proton beams: initial clinical experience. Int J Radiat Oncol Biol Phys. 2006 Nov 1; 66(3):691-8.
    View in: PubMed
  28. Zabicki K, Colbert JA, Dominguez FJ, Gadd MA, Hughes KS, Jones JL, Specht MC, Michaelson JS, Smith BL. Breast cancer diagnosis in women < or = 40 versus 50 to 60 years: increasing size and stage disparity compared with older women over time. Ann Surg Oncol. 2006 Aug; 13(8):1072-7.
    View in: PubMed
  29. Taghian AG, Kozak KR, Doppke KP, Katz A, Smith BL, Gadd M, Specht M, Hughes K, Braaten K, Kachnic LA, Recht A, Powell SN. Initial dosimetric experience using simple three-dimensional conformal external-beam accelerated partial-breast irradiation. Int J Radiat Oncol Biol Phys. 2006 Mar 15; 64(4):1092-9.
    View in: PubMed
  30. Jones JL, Zabicki K, Christian RL, Gadd MA, Hughes KS, Lesnikoski BA, Rhei E, Specht MC, Dominguez FJ, Smith BL. A comparison of sentinel node biopsy before and after neoadjuvant chemotherapy: timing is important. Am J Surg. 2005 Oct; 190(4):517-20.
    View in: PubMed
  31. Specht MC, Kattan MW, Gonen M, Fey J, Van Zee KJ. Predicting nonsentinel node status after positive sentinel lymph biopsy for breast cancer: clinicians versus nomogram. Ann Surg Oncol. 2005 Aug; 12(8):654-9.
    View in: PubMed
  32. Specht MC, Fey JV, Borgen PI, Cody HS. Is the clinically positive axilla in breast cancer really a contraindication to sentinel lymph node biopsy? J Am Coll Surg. 2005 Jan; 200(1):10-4.
    View in: PubMed
  33. Specht MC, Borgen PI, Fey J, Zhang Z, Sclafani L. Personal health behaviors in women who have undergone risk-reducing mastectomy. Am J Surg. 2004 Oct; 188(4):448-9.
    View in: PubMed
  34. Talmor M, Patel MP, Spann MD, Barden C, Specht M, McLean A, Harper A, Hoffman LA, Nolan WB. COX-2 up-regulation in idiopathic carpal tunnel syndrome. Plast Reconstr Surg. 2003 Dec; 112(7):1807-14.
    View in: PubMed
  35. Fritz HG, Brandes H, Bredle DL, Bitterlich A, Vollandt R, Specht M, Franke UF, Wahlers T, Meier-Hellmann A. Post-operative hypoalbuminaemia and procalcitonin elevation for prediction of outcome in cardiopulmonary bypass surgery. Acta Anaesthesiol Scand. 2003 Nov; 47(10):1276-83.
    View in: PubMed
  36. Teng L, Specht MC, Barden CB, Fahey TJ. Antisense hTERT inhibits thyroid cancer cell growth. J Clin Endocrinol Metab. 2003 Mar; 88(3):1362-6.
    View in: PubMed
  37. Barden CB, Specht MC, McCarter MD, Daly JM, Fahey TJ. Effects of limited work hours on surgical training. J Am Coll Surg. 2002 Oct; 195(4):531-8.
    View in: PubMed
  38. Specht M, Pareek G, Lin DD, Bleustein C, Fahey TJ, Felsen D, Poppas DP. Hand-assisted laparoscopic autoaugmentation gastrocystoplasty. Surg Endosc. 2002 Nov; 16(11):1538-41.
    View in: PubMed
  39. Specht MC, Tucker ON, Hocever M, Gonzalez D, Teng L, Fahey TJ. Cyclooxygenase-2 expression in thyroid nodules. J Clin Endocrinol Metab. 2002 Jan; 87(1):358-63.
    View in: PubMed
  40. Specht MC, Barden CB, Fahey TJ. p44/p42-MAP kinase expression in papillary thyroid carcinomas. Surgery. 2001 Dec; 130(6):936-40.
    View in: PubMed
  41. Specht MC, Romero M, Barden CB, Esposito C, Fahey TJ. Characterisitcs of patients having thyroid surgery under regional anesthesia. J Am Coll Surg. 2001 Oct; 193(4):367-72.
    View in: PubMed
  42. Pareek G, Specht M, Lin DD, Petratos PB, Fahey TJ, Soslow RA, Felsen D, Poppas DP. Hand-assisted demucosalized gastrocystoplasty comparing different tissue closure methods. Urology. 2001 Oct; 58(4):625-30.
    View in: PubMed
  43. Meier-Hellmann A, Bredle DL, Specht M, Spies C, Hannemann L, Reinhart K. The effects of low-dose dopamine on splanchnic blood flow and oxygen uptake in patients with septic shock. Intensive Care Med. 1997 Jan; 23(1):31-7.
    View in: PubMed
  44. Spies CD, Dubisz N, Neumann T, Blum S, Müller C, Rommelspacher H, Brummer G, Specht M, Sanft C, Hannemann L, Striebel HW, Schaffartzik W. Therapy of alcohol withdrawal syndrome in intensive care unit patients following trauma: results of a prospective, randomized trial. Crit Care Med. 1996 Mar; 24(3):414-22.
    View in: PubMed
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