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Keywords
Last Name
Institution

Joseph Vincent Bonventre, PH.D., M.D.

TitleSamuel A. Levine Professor of Medicine
InstitutionBrigham and Women's Hospital
DepartmentMedicine
AddressBrigham and Women's Hospital
Medicine
75 Francis St
Boston MA 02115
Phone617/525-5966
Fax617/525-5965

 Mentoring 
 completed student projects
Kidney Injury Molecule -1 in lipid ingestion, storage, and inflammation.
Summer, 06/01/09 - 08/20/09

 Bibliographic 
 selected publications
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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  1. Yun B, Lee H, Ghosh M, Cravatt BF, Hsu KL, Bonventre JV, Ewing H, Gelb MH, Leslie CC. Serine hydrolase inhibitors block necrotic cell death by preventing calcium overload of the mitochondria and permeability transition pore formation. J Biol Chem. 2014 Jan 17; 289(3):1491-504.
    View in: PubMed
  2. Fahmy N, Sener A, Sabbisetti V, Nott L, Lang RM, Welk BK, Méndez-Probst CE, Macphee RA, Vaneerdewijk S, Cadieux PA, Bonventre JV, Razvi H. Urinary expression of novel tissue markers of kidney injury after ureteroscopy, shockwave lithotripsy, and in normal healthy controls. J Endourol. 2013 Dec; 27(12):1455-62.
    View in: PubMed
  3. Bonventre JV. Antifibrotic vitamin D analogs. J Clin Invest. 2013 Nov 1; 123(11):4570-3.
    View in: PubMed
  4. Freedman BS, Lam AQ, Sundsbak JL, Iatrino R, Su X, Koon SJ, Wu M, Daheron L, Harris PC, Zhou J, Bonventre JV. Reduced Ciliary Polycystin-2 in Induced Pluripotent Stem Cells from Polycystic Kidney Disease Patients with PKD1 Mutations. J Am Soc Nephrol. 2013 Oct; 24(10):1571-86.
    View in: PubMed
  5. Waikar SS, Betensky RA, Emerson SC, Bonventre JV. Imperfect gold standards for biomarker evaluation. Clin Trials. 2013; 10(5):696-700.
    View in: PubMed
  6. Humphreys BD, Xu F, Sabbisetti V, Grgic I, Naini SM, Wang N, Chen G, Xiao S, Patel D, Henderson JM, Ichimura T, Mou S, Soeung S, McMahon AP, Kuchroo VK, Bonventre JV. Chronic epithelial kidney injury molecule-1 expression causes murine kidney fibrosis. J Clin Invest. 2013 Sep 3; 123(9):4023-35.
    View in: PubMed
  7. Suram S, Silveira LJ, Mahaffey S, Brown GD, Bonventre JV, Williams DL, Gow NA, Bratton DL, Murphy RC, Leslie CC. Cytosolic phospholipase a2a and eicosanoids regulate expression of genes in macrophages involved in host defense and inflammation. PLoS One. 2013; 8(7):e69002.
    View in: PubMed
  8. Bonventre JV, Basile D, Liu KD, McKay D, Molitoris BA, Nath KA, Nickolas TL, Okusa MD, Palevsky PM, Schnellmann R, Rys-Sikora K, Kimmel PL, Star RA. AKI: A Path Forward. Clin J Am Soc Nephrol. 2013 Sep; 8(9):1606-8.
    View in: PubMed
  9. Susantitaphong P, Perianayagam MC, Tighiouart H, Liangos O, Bonventre JV, Jaber BL. Tumor necrosis factor alpha promoter polymorphism and severity of acute kidney injury. Nephron Clin Pract. 2013; 123(1-2):67-73.
    View in: PubMed
  10. Tögel FE, Bonventre JV. Multipotent mesenchymal stromal cells protect against kidney injury. Cytotherapy. 2013 Jun; 15(6):629-31.
    View in: PubMed
  11. Timsit MO, Adams WJ, Laguna-Fernandez A, Ichimura T, Bonventre JV, García-Cardeña G, Tullius SG. Flow is Critical for Maintaining a Protective Phenotype in Renal Proximal Tubular Cells. Am J Transplant. 2013 Jun; 13(6):1617-8.
    View in: PubMed
  12. Greenberg JO, Vakharia N, Szent-Gyorgyi LE, Desai SP, Turchin A, Forman J, Bonventre JV, Kachalia A. Meaningful measurement: developing a measurement system to improve blood pressure control in patients with chronic kidney disease. J Am Med Inform Assoc. 2013 Jun; 20(e1):e97-e101.
    View in: PubMed
  13. Nishihara K, Masuda S, Shinke H, Ozawa A, Ichimura T, Yonezawa A, Nakagawa S, Inui K, Bonventre JV, Matsubara K. Urinary chemokine (C-C motif) ligand 2 (monocyte chemotactic protein-1) as a tubular injury marker for early detection of cisplatin-induced nephrotoxicity. Biochem Pharmacol. 2013 Feb 15; 85(4):570-82.
    View in: PubMed
  14. Milwid JM, Ichimura T, Li M, Jiao Y, Lee J, Yarmush JS, Parekkadan B, Tilles AW, Bonventre JV, Yarmush ML. Secreted factors from bone marrow stromal cells upregulate IL-10 and reverse acute kidney injury. Stem Cells Int. 2012; 2012:392050.
    View in: PubMed
  15. Salahudeen AK, Bonventre JV. Onconephrology: The Latest Frontier in the War against Kidney Disease. J Am Soc Nephrol. 2013 Jan; 24(1):26-30.
    View in: PubMed
  16. Sangoi AR, McKenney JK, Brooks JD, Bonventre JV, Higgins JP. Evaluation of putative renal cell carcinoma markers PAX-2, PAX-8, and hKIM-1 in germ cell tumors: a tissue microarray study of 100 cases. Appl Immunohistochem Mol Morphol. 2012 Oct; 20(5):451-3.
    View in: PubMed
  17. Sabbisetti VS, Ito K, Wang C, Yang L, Mefferd SC, Bonventre JV. Novel Assays for Detection of Urinary KIM-1 in Mouse Models of Kidney Injury. Toxicol Sci. 2012 Jan; 131(1):13-25.
    View in: PubMed
  18. Bonventre JV. Can we target tubular damage to prevent renal function decline in diabetes? Semin Nephrol. 2012 Sep; 32(5):452-62.
    View in: PubMed
  19. Krolewski AS, Bonventre JV. High risk of ESRD in type 1 diabetes: call for action: introduction. Semin Nephrol. 2012 Sep; 32(5):405-6.
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  20. Krolewski AS, Bonventre JV. High risk of ESRD in type 1 diabetes: new strategies are needed to retard progressive renal function decline. Semin Nephrol. 2012 Sep; 32(5):407-14.
    View in: PubMed
  21. McWilliam SJ, Antoine DJ, Sabbisetti V, Turner MA, Farragher T, Bonventre JV, Park BK, Smyth RL, Pirmohamed M. Mechanism-based urinary biomarkers to identify the potential for aminoglycoside-induced nephrotoxicity in premature neonates: a proof-of-concept study. PLoS One. 2012; 7(8):e43809.
    View in: PubMed
  22. Xiao S, Brooks CR, Zhu C, Wu C, Sweere JM, Petecka S, Yeste A, Quintana FJ, Ichimura T, Sobel RA, Bonventre JV, Kuchroo VK. Defect in regulatory B-cell function and development of systemic autoimmunity in T-cell Ig mucin 1 (Tim-1) mucin domain-mutant mice. Proc Natl Acad Sci U S A. 2012 Jul 24; 109(30):12105-10.
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  23. Peralta CA, Katz R, Bonventre JV, Sabbisetti V, Siscovick D, Sarnak M, Shlipak MG. Associations of Urinary Levels of Kidney Injury Molecule 1 (KIM-1) and Neutrophil Gelatinase-Associated Lipocalin (NGAL) With Kidney Function Decline in the Multi-Ethnic Study of Atherosclerosis (MESA). Am J Kidney Dis. 2012 Dec; 60(6):904-11.
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  24. Bonventre JV. Limb ischemia protects against contrast-induced nephropathy. Circulation. 2012 Jul 24; 126(4):384-7.
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  25. Sengupta P, Basu S, Soni S, Pandey A, Roy B, Oh MS, Chin KT, Paraskar AS, Sarangi S, Connor Y, Sabbisetti VS, Kopparam J, Kulkarni A, Muto K, Amarasiriwardena C, Jayawardene I, Lupoli N, Dinulescu DM, Bonventre JV, Mashelkar RA, Sengupta S. Cholesterol-tethered platinum II-based supramolecular nanoparticle increases antitumor efficacy and reduces nephrotoxicity. Proc Natl Acad Sci U S A. 2012 Jul 10; 109(28):11294-9.
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  26. Kurusu S, Sapirstein A, Bonventre JV. Group IVA phospholipase A2 optimizes ovulation and fertilization in rodents through induction of and metabolic coupling with prostaglandin endoperoxide synthase 2. FASEB J. 2012 Sep; 26(9):3800-10.
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  27. Vermeulen R, Zhang L, Spierenburg A, Tang X, Bonventre JV, Reiss B, Shen M, Smith MT, Qiu C, Ge Y, Ji Z, Xiong J, He J, Hao Z, Liu S, Xie Y, Yue F, Guo W, Purdue M, Beane Freeman LE, Sabbisetti V, Li L, Huang H, Rothman N, Lan Q. Elevated urinary levels of kidney injury molecule-1 among Chinese factory workers exposed to trichloroethylene. Carcinogenesis. 2012 Aug; 33(8):1538-41.
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  28. Ichimura T, Brooks CR, Bonventre JV. Kim-1/Tim-1 and immune cells: shifting sands. Kidney Int. 2012 May; 81(9):809-11.
    View in: PubMed
  29. Mizuguchi KA, Mitani A, Waikar SS, Ireland P, Panizales C, Deluke G, Sugarbaker DJ, Bonventre JV, Frendl G. Use of postoperative creatinine to predict sustained kidney injury in patients undergoing mesothelioma surgery. Clin J Am Soc Nephrol. 2012 Jul; 7(7):1071-8.
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  30. Grgic I, Campanholle G, Bijol V, Wang C, Sabbisetti VS, Ichimura T, Humphreys BD, Bonventre JV. Targeted proximal tubule injury triggers interstitial fibrosis and glomerulosclerosis. Kidney Int. 2012 Jul; 82(2):172-83.
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  31. Nejat M, Pickering JW, Devarajan P, Bonventre JV, Edelstein CL, Walker RJ, Endre ZH. Some biomarkers of acute kidney injury are increased in pre-renal acute injury. Kidney Int. 2012 Jun; 81(12):1254-62.
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  32. Grgic I, Brooks CR, Hofmeister AF, Bijol V, Bonventre JV, Humphreys BD. Imaging of podocyte foot processes by fluorescence microscopy. J Am Soc Nephrol. 2012 May; 23(5):785-91.
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  33. Roy-Chaudhury P, Yevzlin A, Bonventre JV, Agarwal A, Almehmi A, Besarab A, Dwyer A, Hentschel DM, Kraus M, Maya I, Pflederer T, Schon D, Wu S, Work J. Academic interventional nephrology: a model for training, research, and patient care. Clin J Am Soc Nephrol. 2012 Mar; 7(3):521-4.
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  34. Gardiner L, Akintola A, Chen G, Catania JM, Vaidya V, Burghardt RC, Bonventre JV, Trzeciakowski J, Parrish AR. Structural equation modeling highlights the potential of Kim-1 as a biomarker for chronic kidney disease. Am J Nephrol. 2012; 35(2):152-63.
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  35. Tong Y, Giaime E, Yamaguchi H, Ichimura T, Liu Y, Si H, Cai H, Bonventre JV, Shen J. Loss of leucine-rich repeat kinase 2 causes age-dependent bi-phasic alterations of the autophagy pathway. Mol Neurodegener. 2012; 7:2.
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  36. Ralib AM, Pickering JW, Shaw GM, Devarajan P, Edelstein CL, Bonventre JV, Endre ZH. Test characteristics of urinary biomarkers depend on quantitation method in acute kidney injury. J Am Soc Nephrol. 2012 Feb; 23(2):322-33.
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  37. Kurusu S, Sapirstein A, Sawada H, Kawaminami M, Bonventre JV. Group IVA phospholipase A2 regulates testosterone biosynthesis by murine Leydig cells and is required for timely sexual maturation. Biochem J. 2011 Nov 1; 439(3):403-11.
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  38. Bonventre JV, Yang L. Cellular pathophysiology of ischemic acute kidney injury. J Clin Invest. 2011 Nov; 121(11):4210-21.
    View in: PubMed
  39. Waikar SS, Betensky RA, Emerson SC, Bonventre JV. Imperfect gold standards for kidney injury biomarker evaluation. J Am Soc Nephrol. 2012 Jan; 23(1):13-21.
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  40. Qin Y, Alderliesten MC, Stokman G, Pennekamp P, Bonventre JV, de Heer E, Ichimura T, de Graauw M, Price LS, van de Water B. Focal adhesion kinase signaling mediates acute renal injury induced by ischemia/reperfusion. Am J Pathol. 2011 Dec; 179(6):2766-78.
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  41. Yang L, Humphreys BD, Bonventre JV. Pathophysiology of acute kidney injury to chronic kidney disease: maladaptive repair. Contrib Nephrol. 2011; 174:149-55.
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  42. Jeong EM, Ahn KH, Jeon HJ, Kim HD, Lee HS, Jung SY, Jung KM, Kim SK, Bonventre JV, Kim DK. Purification and characterization of a cytosolic Ca(2+)-independent phospholipase A(2) from bovine brain. Mol Cells. 2011 Nov; 32(5):405-13.
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  43. Kerkelä R, Boucher M, Zaka R, Gao E, Harris D, Piuhola J, Song J, Serpi R, Woulfe KC, Cheung JY, O'Leary E, Bonventre JV, Force T. Cytosolic phospholipase A(2)a protects against ischemia/reperfusion injury in the heart. Clin Transl Sci. 2011 Aug; 4(4):236-42.
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  44. Humphreys BD, Czerniak S, DiRocco DP, Hasnain W, Cheema R, Bonventre JV. Repair of injured proximal tubule does not involve specialized progenitors. Proc Natl Acad Sci U S A. 2011 May 31; 108(22):9226-31.
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  45. Sangoi AR, Fujiwara M, West RB, Montgomery KD, Bonventre JV, Higgins JP, Rouse RV, Gokden N, McKenney JK. Immunohistochemical distinction of primary adrenal cortical lesions from metastatic clear cell renal cell carcinoma: a study of 248 cases. Am J Surg Pathol. 2011 May; 35(5):678-86.
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  46. Endre ZH, Pickering JW, Walker RJ, Devarajan P, Edelstein CL, Bonventre JV, Frampton CM, Bennett MR, Ma Q, Sabbisetti VS, Vaidya VS, Walcher AM, Shaw GM, Henderson SJ, Nejat M, Schollum JB, George PM. Improved performance of urinary biomarkers of acute kidney injury in the critically ill by stratification for injury duration and baseline renal function. Kidney Int. 2011 May; 79(10):1119-30.
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  47. Frasch SC, Fernandez-Boyanapalli RF, Berry KZ, Leslie CC, Bonventre JV, Murphy RC, Henson PM, Bratton DL. Signaling via macrophage G2A enhances efferocytosis of dying neutrophils by augmentation of Rac activity. J Biol Chem. 2011 Apr 8; 286(14):12108-22.
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  48. Lee HJ, Park J, Yoon OJ, Kim HW, Lee do Y, Kim do H, Lee WB, Lee NE, Bonventre JV, Kim SS. Amine-modified single-walled carbon nanotubes protect neurons from injury in a rat stroke model. Nat Nanotechnol. 2011 Feb; 6(2):121-5.
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  49. Ly JP, Onay T, Sison K, Sivaskandarajah G, Sabbisetti V, Li L, Bonventre JV, Flenniken A, Paragas N, Barasch JM, Adamson SL, Osborne L, Rossant J, Schnermann J, Quaggin SE. The Sweet Pee model for Sglt2 mutation. J Am Soc Nephrol. 2011 Jan; 22(1):113-23.
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  50. Bonventre JV, Yang L. Kidney injury molecule-1. Curr Opin Crit Care. 2010 Dec; 16(6):556-61.
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  51. Vaidya VS, Niewczas MA, Ficociello LH, Johnson AC, Collings FB, Warram JH, Krolewski AS, Bonventre JV. Regression of microalbuminuria in type 1 diabetes is associated with lower levels of urinary tubular injury biomarkers, kidney injury molecule-1, and N-acetyl-ß-D-glucosaminidase. Kidney Int. 2011 Feb; 79(4):464-70.
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  52. Koyner JL, Vaidya VS, Bennett MR, Ma Q, Worcester E, Akhter SA, Raman J, Jeevanandam V, O'Connor MF, Devarajan P, Bonventre JV, Murray PT. Urinary biomarkers in the clinical prognosis and early detection of acute kidney injury. Clin J Am Soc Nephrol. 2010 Dec; 5(12):2154-65.
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  53. Li B, Castano AP, Hudson TE, Nowlin BT, Lin SL, Bonventre JV, Swanson KD, Duffield JS. The melanoma-associated transmembrane glycoprotein Gpnmb controls trafficking of cellular debris for degradation and is essential for tissue repair. FASEB J. 2010 Dec; 24(12):4767-81.
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  54. Krishnamoorthy A, Clement ME, O'Leary E, Bonventre JV, Vaidya VS. TIM2 gene deletion results in susceptibility to cisplatin-induced kidney toxicity. Toxicol Sci. 2010 Nov; 118(1):298-306.
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  55. Damman K, Van Veldhuisen DJ, Navis G, Vaidya VS, Smilde TD, Westenbrink BD, Bonventre JV, Voors AA, Hillege HL. Tubular damage in chronic systolic heart failure is associated with reduced survival independent of glomerular filtration rate. Heart. 2010 Aug; 96(16):1297-302.
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  56. Suram S, Gangelhoff TA, Taylor PR, Rosas M, Brown GD, Bonventre JV, Akira S, Uematsu S, Williams DL, Murphy RC, Leslie CC. Pathways regulating cytosolic phospholipase A2 activation and eicosanoid production in macrophages by Candida albicans. J Biol Chem. 2010 Oct 1; 285(40):30676-85.
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  57. Waikar SS, Sabbisetti VS, Bonventre JV. Normalization of urinary biomarkers to creatinine during changes in glomerular filtration rate. Kidney Int. 2010 Sep; 78(5):486-94.
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  58. Yang L, Besschetnova TY, Brooks CR, Shah JV, Bonventre JV. Epithelial cell cycle arrest in G2/M mediates kidney fibrosis after injury. Nat Med. 2010 May; 16(5):535-43, 1p following 143.
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  59. Vaidya VS, Ozer JS, Dieterle F, Collings FB, Ramirez V, Troth S, Muniappa N, Thudium D, Gerhold D, Holder DJ, Bobadilla NA, Marrer E, Perentes E, Cordier A, Vonderscher J, Maurer G, Goering PL, Sistare FD, Bonventre JV. Kidney injury molecule-1 outperforms traditional biomarkers of kidney injury in preclinical biomarker qualification studies. Nat Biotechnol. 2010 May; 28(5):478-85.
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  60. Bonventre JV, Vaidya VS, Schmouder R, Feig P, Dieterle F. Next-generation biomarkers for detecting kidney toxicity. Nat Biotechnol. 2010 May; 28(5):436-40.
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  61. Bonventre JV. Pathophysiology of AKI: injury and normal and abnormal repair. Contrib Nephrol. 2010; 165:9-17.
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  62. Kim J, Kim DS, Park MJ, Cho HJ, Zervos AS, Bonventre JV, Park KM. Omi/HtrA2 protease is associated with tubular cell apoptosis and fibrosis induced by unilateral ureteral obstruction. Am J Physiol Renal Physiol. 2010 Jun; 298(6):F1332-40.
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  63. Espandiari P, Rosenzweig B, Zhang J, Zhou Y, Schnackenberg L, Vaidya VS, Goering PL, Brown RP, Bonventre JV, Mahjoob K, Holland RD, Beger RD, Thompson K, Hanig J, Sadrieh N. Age-related differences in susceptibility to cisplatin-induced renal toxicity. J Appl Toxicol. 2010 Mar; 30(2):172-82.
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  64. Hoffmann D, Adler M, Vaidya VS, Rached E, Mulrane L, Gallagher WM, Callanan JJ, Gautier JC, Matheis K, Staedtler F, Dieterle F, Brandenburg A, Sposny A, Hewitt P, Ellinger-Ziegelbauer H, Bonventre JV, Dekant W, Mally A. Performance of novel kidney biomarkers in preclinical toxicity studies. Toxicol Sci. 2010 Jul; 116(1):8-22.
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  65. Nishihara K, Masuda S, Nakagawa S, Yonezawa A, Ichimura T, Bonventre JV, Inui K. Impact of Cyclin B2 and Cell division cycle 2 on tubular hyperplasia in progressive chronic renal failure rats. Am J Physiol Renal Physiol. 2010 Apr; 298(4):F923-34.
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  66. Schröppel B, Krüger B, Walsh L, Yeung M, Harris S, Garrison K, Himmelfarb J, Lerner SM, Bromberg JS, Zhang PL, Bonventre JV, Wang Z, Farris AB, Colvin RB, Murphy BT, Vella JP. Tubular expression of KIM-1 does not predict delayed function after transplantation. J Am Soc Nephrol. 2010 Mar; 21(3):536-42.
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  67. Humphreys BD, Lin SL, Kobayashi A, Hudson TE, Nowlin BT, Bonventre JV, Valerius MT, McMahon AP, Duffield JS. Fate tracing reveals the pericyte and not epithelial origin of myofibroblasts in kidney fibrosis. Am J Pathol. 2010 Jan; 176(1):85-97.
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  68. Ferguson MA, Vaidya VS, Waikar SS, Collings FB, Sunderland KE, Gioules CJ, Bonventre JV. Urinary liver-type fatty acid-binding protein predicts adverse outcomes in acute kidney injury. Kidney Int. 2010 Apr; 77(8):708-14.
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  69. Waikar SS, Betensky RA, Bonventre JV. Creatinine as the gold standard for kidney injury biomarker studies? Nephrol Dial Transplant. 2009 Nov; 24(11):3263-5.
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  70. Liangos O, Tighiouart H, Perianayagam MC, Kolyada A, Han WK, Wald R, Bonventre JV, Jaber BL. Comparative analysis of urinary biomarkers for early detection of acute kidney injury following cardiopulmonary bypass. Biomarkers. 2009 Sep; 14(6):423-31.
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  71. Lamour NF, Subramanian P, Wijesinghe DS, Stahelin RV, Bonventre JV, Chalfant CE. Ceramide 1-phosphate is required for the translocation of group IVA cytosolic phospholipase A2 and prostaglandin synthesis. J Biol Chem. 2009 Sep 25; 284(39):26897-907.
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  72. Zhang J, Goering PL, Espandiari P, Shaw M, Bonventre JV, Vaidya VS, Brown RP, Keenan J, Kilty CG, Sadrieh N, Hanig JP. Differences in immunolocalization of Kim-1, RPA-1, and RPA-2 in kidneys of gentamicin-, cisplatin-, and valproic acid-treated rats: potential role of iNOS and nitrotyrosine. Toxicol Pathol. 2009 Aug; 37(5):629-43.
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  73. Nijboer WN, Schuurs TA, Damman J, van Goor H, Vaidya VS, van der Heide JJ, Leuvenink HG, Bonventre JV, Ploeg RJ. Kidney injury molecule-1 is an early noninvasive indicator for donor brain death-induced injury prior to kidney transplantation. Am J Transplant. 2009 Aug; 9(8):1752-9.
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  74. Parti RP, Loper R, Brown GD, Gordon S, Taylor PR, Bonventre JV, Murphy RC, Williams DL, Leslie CC. Cytosolic phospholipase a2 activation by Candida albicans in alveolar macrophages: role of dectin-1. Am J Respir Cell Mol Biol. 2010 Apr; 42(4):415-23.
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  75. Bonventre JV. Microvesicles from mesenchymal stromal cells protect against acute kidney injury. J Am Soc Nephrol. 2009 May; 20(5):927-8.
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  76. Vaidya VS, Ford GM, Waikar SS, Wang Y, Clement MB, Ramirez V, Glaab WE, Troth SP, Sistare FD, Prozialeck WC, Edwards JR, Bobadilla NA, Mefferd SC, Bonventre JV. A rapid urine test for early detection of kidney injury. Kidney Int. 2009 Jul; 76(1):108-14.
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  77. Sieber M, Hoffmann D, Adler M, Vaidya VS, Clement M, Bonventre JV, Zidek N, Rached E, Amberg A, Callanan JJ, Dekant W, Mally A. Comparative analysis of novel noninvasive renal biomarkers and metabonomic changes in a rat model of gentamicin nephrotoxicity. Toxicol Sci. 2009 Jun; 109(2):336-49.
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  78. Takakura A, Contrino L, Zhou X, Bonventre JV, Sun Y, Humphreys BD, Zhou J. Renal injury is a third hit promoting rapid development of adult polycystic kidney disease. Hum Mol Genet. 2009 Jul 15; 18(14):2523-31.
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  79. Bonventre JV. Kidney injury molecule-1 (KIM-1): a urinary biomarker and much more. Nephrol Dial Transplant. 2009 Nov; 24(11):3265-8.
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  80. Waikar SS, Bonventre JV. Creatinine kinetics and the definition of acute kidney injury. J Am Soc Nephrol. 2009 Mar; 20(3):672-9.
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  81. Kramer AB, van Timmeren MM, Schuurs TA, Vaidya VS, Bonventre JV, van Goor H, Navis G. Reduction of proteinuria in adriamycin-induced nephropathy is associated with reduction of renal kidney injury molecule (Kim-1) over time. Am J Physiol Renal Physiol. 2009 May; 296(5):F1136-45.
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  82. Prozialeck WC, Edwards JR, Vaidya VS, Bonventre JV. Preclinical evaluation of novel urinary biomarkers of cadmium nephrotoxicity. Toxicol Appl Pharmacol. 2009 Aug 1; 238(3):301-5.
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  83. Prozialeck WC, Edwards JR, Lamar PC, Liu J, Vaidya VS, Bonventre JV. Expression of kidney injury molecule-1 (Kim-1) in relation to necrosis and apoptosis during the early stages of Cd-induced proximal tubule injury. Toxicol Appl Pharmacol. 2009 Aug 1; 238(3):306-14.
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  84. Cheong JK, Gunaratnam L, Zang ZJ, Yang CM, Sun X, Nasr SL, Sim KG, Peh BK, Rashid SB, Bonventre JV, Salto-Tellez M, Hsu SI. TRIP-Br2 promotes oncogenesis in nude mice and is frequently overexpressed in multiple human tumors. J Transl Med. 2009; 7:8.
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  85. Gunaratnam L, Bonventre JV. HIF in kidney disease and development. J Am Soc Nephrol. 2009 Sep; 20(9):1877-87.
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  86. Kim J, Kim KY, Jang HS, Yoshida T, Tsuchiya K, Nitta K, Park JW, Bonventre JV, Park KM. Role of cytosolic NADP+-dependent isocitrate dehydrogenase in ischemia-reperfusion injury in mouse kidney. Am J Physiol Renal Physiol. 2009 Mar; 296(3):F622-33.
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  87. Vaidya VS, Waikar SS, Ferguson MA, Collings FB, Sunderland K, Gioules C, Bradwin G, Matsouaka R, Betensky RA, Curhan GC, Bonventre JV. Urinary biomarkers for sensitive and specific detection of acute kidney injury in humans. Clin Transl Sci. 2008 Dec; 1(3):200-8.
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  88. Chagnon F, Vaidya VS, Plante GE, Bonventre JV, Bernard A, Guindi C, Lesur O. Modulation of aquaporin-2/vasopressin2 receptor kidney expression and tubular injury after endotoxin (lipopolysaccharide) challenge. Crit Care Med. 2008 Nov; 36(11):3054-61.
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  89. Sanchez-Mejia RO, Newman JW, Toh S, Yu GQ, Zhou Y, Halabisky B, Cissé M, Scearce-Levie K, Cheng IH, Gan L, Palop JJ, Bonventre JV, Mucke L. Phospholipase A2 reduction ameliorates cognitive deficits in a mouse model of Alzheimer's disease. Nat Neurosci. 2008 Nov; 11(11):1311-8.
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  90. Zang ZJ, Gunaratnam L, Cheong JK, Lai LY, Hsiao LL, O'Leary E, Sun X, Salto-Tellez M, Bonventre JV, Hsu SI. Identification of PP2A as a novel interactor and regulator of TRIP-Br1. Cell Signal. 2009 Jan; 21(1):34-42.
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  91. Waanders F, Vaidya VS, van Goor H, Leuvenink H, Damman K, Hamming I, Bonventre JV, Vogt L, Navis G. Effect of renin-angiotensin-aldosterone system inhibition, dietary sodium restriction, and/or diuretics on urinary kidney injury molecule 1 excretion in nondiabetic proteinuric kidney disease: a post hoc analysis of a randomized controlled trial. Am J Kidney Dis. 2009 Jan; 53(1):16-25.
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  92. Trujillo J, Cruz C, Tovar A, Vaidya V, Zambrano E, Bonventre JV, Gamba G, Torres N, Bobadilla NA. Renoprotective mechanisms of soy protein intake in the obese Zucker rat. Am J Physiol Renal Physiol. 2008 Nov; 295(5):F1574-82.
    View in: PubMed
  93. Waikar SS, Bonventre JV. Biomarkers for the diagnosis of acute kidney injury. Nephron Clin Pract. 2008; 109(4):c192-7.
    View in: PubMed
  94. Bellomo R, Bonventre J. Acute kidney injury - scientific evidence driving change in patient management. Introduction. Nephron Clin Pract. 2008; 109(4):c181.
    View in: PubMed
  95. Taylor AL, Bonventre JV, Uliasz TF, Hewett JA, Hewett SJ. Cytosolic phospholipase A2 alpha inhibition prevents neuronal NMDA receptor-stimulated arachidonic acid mobilization and prostaglandin production but not subsequent cell death. J Neurochem. 2008 Aug; 106(4):1828-40.
    View in: PubMed
  96. Bonventre JV. Dialysis in acute kidney injury--more is not better. N Engl J Med. 2008 Jul 3; 359(1):82-4.
    View in: PubMed
  97. Ichimura T, Asseldonk EJ, Humphreys BD, Gunaratnam L, Duffield JS, Bonventre JV. Kidney injury molecule-1 is a phosphatidylserine receptor that confers a phagocytic phenotype on epithelial cells. J Clin Invest. 2008 May; 118(5):1657-68.
    View in: PubMed
  98. Zhang J, Brown RP, Shaw M, Vaidya VS, Zhou Y, Espandiari P, Sadrieh N, Stratmeyer M, Keenan J, Kilty CG, Bonventre JV, Goering PL. Immunolocalization of Kim-1, RPA-1, and RPA-2 in kidney of gentamicin-, mercury-, or chromium-treated rats: relationship to renal distributions of iNOS and nitrotyrosine. Toxicol Pathol. 2008 Apr; 36(3):397-409.
    View in: PubMed
  99. Humphreys BD, Valerius MT, Kobayashi A, Mugford JW, Soeung S, Duffield JS, McMahon AP, Bonventre JV. Intrinsic epithelial cells repair the kidney after injury. Cell Stem Cell. 2008 Mar 6; 2(3):284-91.
    View in: PubMed
  100. Zeidel M, Bonventre J, Forrest J, Sukhatme V. A national course for renal fellows: the origins of renal physiology. J Am Soc Nephrol. 2008 Apr; 19(4):649-50.
    View in: PubMed
  101. Murray PT, Devarajan P, Levey AS, Eckardt KU, Bonventre JV, Lombardi R, Herget-Rosenthal S, Levin A. A framework and key research questions in AKI diagnosis and staging in different environments. Clin J Am Soc Nephrol. 2008 May; 3(3):864-8.
    View in: PubMed
  102. Cubells L, Vilà de Muga S, Tebar F, Bonventre JV, Balsinde J, Pol A, Grewal T, Enrich C. Annexin A6-induced inhibition of cytoplasmic phospholipase A2 is linked to caveolin-1 export from the Golgi. J Biol Chem. 2008 Apr 11; 283(15):10174-83.
    View in: PubMed
  103. Ferguson MA, Vaidya VS, Bonventre JV. Biomarkers of nephrotoxic acute kidney injury. Toxicology. 2008 Mar 20; 245(3):182-93.
    View in: PubMed
  104. Humphreys BD, Bonventre JV. Mesenchymal stem cells in acute kidney injury. Annu Rev Med. 2008; 59:311-25.
    View in: PubMed
  105. Vaidya VS, Ferguson MA, Bonventre JV. Biomarkers of acute kidney injury. Annu Rev Pharmacol Toxicol. 2008; 48:463-93.
    View in: PubMed
  106. Bonventre JV. Kidney Injury Molecule-1 (KIM-1): a specific and sensitive biomarker of kidney injury. Scand J Clin Lab Invest Suppl. 2008; 241:78-83.
    View in: PubMed
  107. van Timmeren MM, Vaidya VS, van Ree RM, Oterdoom LH, de Vries AP, Gans RO, van Goor H, Stegeman CA, Bonventre JV, Bakker SJ. High urinary excretion of kidney injury molecule-1 is an independent predictor of graft loss in renal transplant recipients. Transplantation. 2007 Dec 27; 84(12):1625-30.
    View in: PubMed
  108. Zhang PL, Rothblum LI, Han WK, Blasick TM, Potdar S, Bonventre JV. Kidney injury molecule-1 expression in transplant biopsies is a sensitive measure of cell injury. Kidney Int. 2008 Mar; 73(5):608-14.
    View in: PubMed
  109. Lock EA, Bonventre JV. Biomarkers in translation; past, present and future. Toxicology. 2008 Mar 20; 245(3):163-6.
    View in: PubMed
  110. Noor S, Goldfine H, Tucker DE, Suram S, Lenz LL, Akira S, Uematsu S, Girotti M, Bonventre JV, Breuel K, Williams DL, Leslie CC. Activation of cytosolic phospholipase A2alpha in resident peritoneal macrophages by Listeria monocytogenes involves listeriolysin O and TLR2. J Biol Chem. 2008 Feb 22; 283(8):4744-55.
    View in: PubMed
  111. Han WK, Waikar SS, Johnson A, Betensky RA, Dent CL, Devarajan P, Bonventre JV. Urinary biomarkers in the early diagnosis of acute kidney injury. Kidney Int. 2008 Apr; 73(7):863-9.
    View in: PubMed
  112. Bonventre JV. Urine neutrophil gelatinase-associated lipocalin as a marker of acute kidney injury in critically ill children. Nat Clin Pract Nephrol. 2008 Feb; 4(2):78-9.
    View in: PubMed
  113. Waikar SS, Bonventre JV. Biomarkers for the diagnosis of acute kidney injury. Curr Opin Nephrol Hypertens. 2007 Nov; 16(6):557-64.
    View in: PubMed
  114. Zhou Y, Vaidya VS, Brown RP, Zhang J, Rosenzweig BA, Thompson KL, Miller TJ, Bonventre JV, Goering PL. Comparison of kidney injury molecule-1 and other nephrotoxicity biomarkers in urine and kidney following acute exposure to gentamicin, mercury, and chromium. Toxicol Sci. 2008 Jan; 101(1):159-70.
    View in: PubMed
  115. Muñoz NM, Meliton AY, Arm JP, Bonventre JV, Cho W, Leff AR. Deletion of secretory group V phospholipase A2 attenuates cell migration and airway hyperresponsiveness in immunosensitized mice. J Immunol. 2007 Oct 1; 179(7):4800-7.
    View in: PubMed
  116. Zhang Z, Humphreys BD, Bonventre JV. Shedding of the urinary biomarker kidney injury molecule-1 (KIM-1) is regulated by MAP kinases and juxtamembrane region. J Am Soc Nephrol. 2007 Oct; 18(10):2704-14.
    View in: PubMed
  117. Hentschel DM, Mengel M, Boehme L, Liebsch F, Albertin C, Bonventre JV, Haller H, Schiffer M. Rapid screening of glomerular slit diaphragm integrity in larval zebrafish. Am J Physiol Renal Physiol. 2007 Nov; 293(5):F1746-50.
    View in: PubMed
  118. Prozialeck WC, Vaidya VS, Liu J, Waalkes MP, Edwards JR, Lamar PC, Bernard AM, Dumont X, Bonventre JV. Kidney injury molecule-1 is an early biomarker of cadmium nephrotoxicity. Kidney Int. 2007 Oct; 72(8):985-93.
    View in: PubMed
  119. Chen G, Bridenbaugh EA, Akintola AD, Catania JM, Vaidya VS, Bonventre JV, Dearman AC, Sampson HW, Zawieja DC, Burghardt RC, Parrish AR. Increased susceptibility of aging kidney to ischemic injury: identification of candidate genes changed during aging, but corrected by caloric restriction. Am J Physiol Renal Physiol. 2007 Oct; 293(4):F1272-81.
    View in: PubMed
  120. Espandiari P, Zhang J, Rosenzweig BA, Vaidya VS, Sun J, Schnackenberg L, Herman EH, Knapton A, Bonventre JV, Beger RD, Thompson KL, Hanig J. The utility of a rodent model in detecting pediatric drug-induced nephrotoxicity. Toxicol Sci. 2007 Oct; 99(2):637-48.
    View in: PubMed
  121. Kikawada E, Bonventre JV, Arm JP. Group V secretory PLA2 regulates TLR2-dependent eicosanoid generation in mouse mast cells through amplification of ERK and cPLA2alpha activation. Blood. 2007 Jul 15; 110(2):561-7.
    View in: PubMed
  122. Lin F, Zhang PL, Yang XJ, Shi J, Blasick T, Han WK, Wang HL, Shen SS, Teh BT, Bonventre JV. Human kidney injury molecule-1 (hKIM-1): a useful immunohistochemical marker for diagnosing renal cell carcinoma and ovarian clear cell carcinoma. Am J Surg Pathol. 2007 Mar; 31(3):371-81.
    View in: PubMed
  123. Humphreys BD, Bonventre JV. The contribution of adult stem cells to renal repair. Nephrol Ther. 2007 Mar; 3(1):3-10.
    View in: PubMed
  124. Ghosh M, Loper R, Ghomashchi F, Tucker DE, Bonventre JV, Gelb MH, Leslie CC. Function, activity, and membrane targeting of cytosolic phospholipase A(2)zeta in mouse lung fibroblasts. J Biol Chem. 2007 Apr 20; 282(16):11676-86.
    View in: PubMed
  125. Liangos O, Perianayagam MC, Vaidya VS, Han WK, Wald R, Tighiouart H, MacKinnon RW, Li L, Balakrishnan VS, Pereira BJ, Bonventre JV, Jaber BL. Urinary N-acetyl-beta-(D)-glucosaminidase activity and kidney injury molecule-1 level are associated with adverse outcomes in acute renal failure. J Am Soc Nephrol. 2007 Mar; 18(3):904-12.
    View in: PubMed
  126. Bonventre JV. Pathophysiology of acute kidney injury: roles of potential inhibitors of inflammation. Contrib Nephrol. 2007; 156:39-46.
    View in: PubMed
  127. Bonventre JV. Diagnosis of acute kidney injury: from classic parameters to new biomarkers. Contrib Nephrol. 2007; 156:213-9.
    View in: PubMed
  128. Perianayagam MC, Liangos O, Kolyada AY, Wald R, MacKinnon RW, Li L, Rao M, Balakrishnan VS, Bonventre JV, Pereira BJ, Jaber BL. NADPH oxidase p22phox and catalase gene variants are associated with biomarkers of oxidative stress and adverse outcomes in acute renal failure. J Am Soc Nephrol. 2007 Jan; 18(1):255-63.
    View in: PubMed
  129. Humphreys BD, Duffield JS, Bonventre JV. Renal stem cells in recovery from acute kidney injury. Minerva Urol Nefrol. 2006 Dec; 58(4):329-37.
    View in: PubMed
  130. Liu L, Zhao R, Bai Y, Stanish LF, Evans JE, Sanderson MJ, Bonventre JV, Rittenhouse AR. M1 muscarinic receptors inhibit L-type Ca2+ current and M-current by divergent signal transduction cascades. J Neurosci. 2006 Nov 8; 26(45):11588-98.
    View in: PubMed
  131. Duffield JS, Hong S, Vaidya VS, Lu Y, Fredman G, Serhan CN, Bonventre JV. Resolvin D series and protectin D1 mitigate acute kidney injury. J Immunol. 2006 Nov 1; 177(9):5902-11.
    View in: PubMed
  132. van de Weyer PS, Muehlfeit M, Klose C, Bonventre JV, Walz G, Kuehn EW. A highly conserved tyrosine of Tim-3 is phosphorylated upon stimulation by its ligand galectin-9. Biochem Biophys Res Commun. 2006 Dec 15; 351(2):571-6.
    View in: PubMed
  133. Vaidya VS, Bonventre JV. Mechanistic biomarkers for cytotoxic acute kidney injury. Expert Opin Drug Metab Toxicol. 2006 Oct; 2(5):697-713.
    View in: PubMed
  134. Rennert PD, Ichimura T, Sizing ID, Bailly V, Li Z, Rennard R, McCoon P, Pablo L, Miklasz S, Tarilonte L, Bonventre JV. T cell, Ig domain, mucin domain-2 gene-deficient mice reveal a novel mechanism for the regulation of Th2 immune responses and airway inflammation. J Immunol. 2006 Oct 1; 177(7):4311-21.
    View in: PubMed
  135. Waikar SS, Bonventre JV. Can we rely on blood urea nitrogen as a biomarker to determine when to initiate dialysis? Clin J Am Soc Nephrol. 2006 Sep; 1(5):903-4.
    View in: PubMed
  136. de Borst MH, van Timmeren MM, Vaidya VS, de Boer RA, van Dalen MB, Kramer AB, Schuurs TA, Bonventre JV, Navis G, van Goor H. Induction of kidney injury molecule-1 in homozygous Ren2 rats is attenuated by blockade of the renin-angiotensin system or p38 MAP kinase. Am J Physiol Renal Physiol. 2007 Jan; 292(1):F313-20.
    View in: PubMed
  137. Pérez-Rojas J, Blanco JA, Cruz C, Trujillo J, Vaidya VS, Uribe N, Bonventre JV, Gamba G, Bobadilla NA. Mineralocorticoid receptor blockade confers renoprotection in preexisting chronic cyclosporine nephrotoxicity. Am J Physiol Renal Physiol. 2007 Jan; 292(1):F131-9.
    View in: PubMed
  138. Kang MS, Jeong JY, Seo JH, Jeon HJ, Jung KM, Chin MR, Moon CK, Bonventre JV, Jung SY, Kim DK. Methylmercury-induced toxicity is mediated by enhanced intracellular calcium through activation of phosphatidylcholine-specific phospholipase C. Toxicol Appl Pharmacol. 2006 Oct 15; 216(2):206-15.
    View in: PubMed
  139. Kim J, Kil IS, Seok YM, Yang ES, Kim DK, Lim DG, Park JW, Bonventre JV, Park KM. Orchiectomy attenuates post-ischemic oxidative stress and ischemia/reperfusion injury in mice. A role for manganese superoxide dismutase. J Biol Chem. 2006 Jul 21; 281(29):20349-56.
    View in: PubMed
  140. Humphreys BD, Duffield JD, Bonventre JV. Renal stem cells in recovery from acute kidney injury. Minerva Urol Nefrol. 2006 Mar; 58(1):13-21.
    View in: PubMed
  141. van Timmeren MM, Bakker SJ, Vaidya VS, Bailly V, Schuurs TA, Damman J, Stegeman CA, Bonventre JV, van Goor H. Tubular kidney injury molecule-1 in protein-overload nephropathy. Am J Physiol Renal Physiol. 2006 Aug; 291(2):F456-64.
    View in: PubMed
  142. Meyer AM, Dwyer-Nield LD, Hurteau G, Keith RL, Ouyang Y, Freed BM, Kisley LR, Geraci MW, Bonventre JV, Nemenoff RA, Malkinson AM. Attenuation of the pulmonary inflammatory response following butylated hydroxytoluene treatment of cytosolic phospholipase A2 null mice. Am J Physiol Lung Cell Mol Physiol. 2006 Jun; 290(6):L1260-6.
    View in: PubMed
  143. Balestrieri B, Hsu VW, Gilbert H, Leslie CC, Han WK, Bonventre JV, Arm JP. Group V secretory phospholipase A2 translocates to the phagosome after zymosan stimulation of mouse peritoneal macrophages and regulates phagocytosis. J Biol Chem. 2006 Mar 10; 281(10):6691-8.
    View in: PubMed
  144. Lechene C, Hillion F, McMahon G, Benson D, Kleinfeld AM, Kampf JP, Distel D, Luyten Y, Bonventre J, Hentschel D, Park KM, Ito S, Schwartz M, Benichou G, Slodzian G. High-resolution quantitative imaging of mammalian and bacterial cells using stable isotope mass spectrometry. J Biol. 2006; 5(6):20.
    View in: PubMed
  145. Stafforini DM, Sheller JR, Blackwell TS, Sapirstein A, Yull FE, McIntyre TM, Bonventre JV, Prescott SM, Roberts LJ. Release of free F2-isoprostanes from esterified phospholipids is catalyzed by intracellular and plasma platelet-activating factor acetylhydrolases. J Biol Chem. 2006 Feb 24; 281(8):4616-23.
    View in: PubMed
  146. Bellomo R, Bonventre J, Macias W, Pinsky M. Management of early acute renal failure: focus on post-injury prevention. Curr Opin Crit Care. 2005 Dec; 11(6):542-7.
    View in: PubMed
  147. Vidal BC, Bonventre JV, I-Hong Hsu S. Towards the application of proteomics in renal disease diagnosis. Clin Sci (Lond). 2005 Nov; 109(5):421-30.
    View in: PubMed
  148. Duffield JS, Bonventre JV. Kidney tubular epithelium is restored without replacement with bone marrow-derived cells during repair after ischemic injury. Kidney Int. 2005 Nov; 68(5):1956-61.
    View in: PubMed
  149. Duffield JS, Tipping PG, Kipari T, Cailhier JF, Clay S, Lang R, Bonventre JV, Hughes J. Conditional ablation of macrophages halts progression of crescentic glomerulonephritis. Am J Pathol. 2005 Nov; 167(5):1207-19.
    View in: PubMed
  150. Chertow GM, Burdick E, Honour M, Bonventre JV, Bates DW. Acute kidney injury, mortality, length of stay, and costs in hospitalized patients. J Am Soc Nephrol. 2005 Nov; 16(11):3365-70.
    View in: PubMed
  151. Vaidya VS, Ramirez V, Ichimura T, Bobadilla NA, Bonventre JV. Urinary kidney injury molecule-1: a sensitive quantitative biomarker for early detection of kidney tubular injury. Am J Physiol Renal Physiol. 2006 Feb; 290(2):F517-29.
    View in: PubMed
  152. Hentschel DM, Bonventre JV. Novel non-rodent models of kidney disease. Curr Mol Med. 2005 Aug; 5(5):537-46.
    View in: PubMed
  153. Muckova K, Duffield JS, Held KD, Bonventre JV, Sheridan AM. cPLA2-interacting protein, PLIP, causes apoptosis and decreases G1 phase in mesangial cells. Am J Physiol Renal Physiol. 2006 Jan; 290(1):F70-9.
    View in: PubMed
  154. Duffield JS, Park KM, Hsiao LL, Kelley VR, Scadden DT, Ichimura T, Bonventre JV. Restoration of tubular epithelial cells during repair of the postischemic kidney occurs independently of bone marrow-derived stem cells. J Clin Invest. 2005 Jul; 115(7):1743-55.
    View in: PubMed
  155. Ilsley JN, Nakanishi M, Flynn C, Belinsky GS, De Guise S, Adib JN, Dobrowsky RT, Bonventre JV, Rosenberg DW. Cytoplasmic phospholipase A2 deletion enhances colon tumorigenesis. Cancer Res. 2005 Apr 1; 65(7):2636-43.
    View in: PubMed
  156. Park KM, Cho HJ, Bonventre JV. Orchiectomy reduces susceptibility to renal ischemic injury: a role for heat shock proteins. Biochem Biophys Res Commun. 2005 Mar 4; 328(1):312-7.
    View in: PubMed
  157. Han WK, Alinani A, Wu CL, Michaelson D, Loda M, McGovern FJ, Thadhani R, Bonventre JV. Human kidney injury molecule-1 is a tissue and urinary tumor marker of renal cell carcinoma. J Am Soc Nephrol. 2005 Apr; 16(4):1126-34.
    View in: PubMed
  158. Lin J, Bonventre JV. Prevention of radiocontrast nephropathy. Curr Opin Nephrol Hypertens. 2005 Mar; 14(2):105-10.
    View in: PubMed
  159. Sapirstein A, Saito H, Texel SJ, Samad TA, O'Leary E, Bonventre JV. Cytosolic phospholipase A2alpha regulates induction of brain cyclooxygenase-2 in a mouse model of inflammation. Am J Physiol Regul Integr Comp Physiol. 2005 Jun; 288(6):R1774-82.
    View in: PubMed
  160. Jaber BL, Pereira BJ, Bonventre JV, Balakrishnan VS. Polymorphism of host response genes: implications in the pathogenesis and treatment of acute renal failure. Kidney Int. 2005 Jan; 67(1):14-33.
    View in: PubMed
  161. Hentschel DM, Park KM, Cilenti L, Zervos AS, Drummond I, Bonventre JV. Acute renal failure in zebrafish: a novel system to study a complex disease. Am J Physiol Renal Physiol. 2005 May; 288(5):F923-9.
    View in: PubMed
  162. Han WK, Bonventre JV. Biologic markers for the early detection of acute kidney injury. Curr Opin Crit Care. 2004 Dec; 10(6):476-82.
    View in: PubMed
  163. Sim KG, Zang Z, Yang CM, Bonventre JV, Hsu SI. TRIP-Br links E2F to novel functions in the regulation of cyclin E expression during cell cycle progression and in the maintenance of genomic stability. Cell Cycle. 2004 Oct; 3(10):1296-304.
    View in: PubMed
  164. Cilenti L, Kyriazis GA, Soundarapandian MM, Stratico V, Yerkes A, Park KM, Sheridan AM, Alnemri ES, Bonventre JV, Zervos AS. Omi/HtrA2 protease mediates cisplatin-induced cell death in renal cells. Am J Physiol Renal Physiol. 2005 Feb; 288(2):F371-9.
    View in: PubMed
  165. Cilenti L, Soundarapandian MM, Kyriazis GA, Stratico V, Singh S, Gupta S, Bonventre JV, Alnemri ES, Zervos AS. Regulation of HAX-1 anti-apoptotic protein by Omi/HtrA2 protease during cell death. J Biol Chem. 2004 Nov 26; 279(48):50295-301.
    View in: PubMed
  166. Park KM, Kim JI, Ahn Y, Bonventre AJ, Bonventre JV. Testosterone is responsible for enhanced susceptibility of males to ischemic renal injury. J Biol Chem. 2004 Dec 10; 279(50):52282-92.
    View in: PubMed
  167. Bonventre JV, Zuk A. Ischemic acute renal failure: an inflammatory disease? Kidney Int. 2004 Aug; 66(2):480-5.
    View in: PubMed
  168. Thio SS, Bonventre JV, Hsu SI. The CtBP2 co-repressor is regulated by NADH-dependent dimerization and possesses a novel N-terminal repression domain. Nucleic Acids Res. 2004; 32(5):1836-47.
    View in: PubMed
  169. Meyer AM, Dwyer-Nield LD, Hurteau GJ, Keith RL, O'Leary E, You M, Bonventre JV, Nemenoff RA, Malkinson AM. Decreased lung tumorigenesis in mice genetically deficient in cytosolic phospholipase A2. Carcinogenesis. 2004 Aug; 25(8):1517-24.
    View in: PubMed
  170. Bonventre JV. Pathophysiology of ischemic acute renal failure. Inflammation, lung-kidney cross-talk, and biomarkers. Contrib Nephrol. 2004; 144:19-30.
    View in: PubMed
  171. Luyckx VA, Bonventre JV. Dose of dialysis in acute renal failure. Semin Dial. 2004 Jan-Feb; 17(1):30-6.
    View in: PubMed
  172. Ichimura T, Hung CC, Yang SA, Stevens JL, Bonventre JV. Kidney injury molecule-1: a tissue and urinary biomarker for nephrotoxicant-induced renal injury. Am J Physiol Renal Physiol. 2004 Mar; 286(3):F552-63.
    View in: PubMed
  173. Andreucci M, Michael A, Kramers C, Park KM, Chen A, Matthaeus T, Alessandrini A, Haq S, Force T, Bonventre JV. Renal ischemia/reperfusion and ATP depletion/repletion in LLC-PK(1) cells result in phosphorylation of FKHR and FKHRL1. Kidney Int. 2003 Oct; 64(4):1189-98.
    View in: PubMed
  174. Bonventre JV. Molecular response to cytotoxic injury: role of inflammation, MAP kinases, and endoplasmic reticulum stress response. Semin Nephrol. 2003 Sep; 23(5):439-48.
    View in: PubMed
  175. Bonventre JV, Weinberg JM. Recent advances in the pathophysiology of ischemic acute renal failure. J Am Soc Nephrol. 2003 Aug; 14(8):2199-210.
    View in: PubMed
  176. Ghosh M, Stewart A, Tucker DE, Bonventre JV, Murphy RC, Leslie CC. Role of cytosolic phospholipase A(2) in prostaglandin E(2) production by lung fibroblasts. Am J Respir Cell Mol Biol. 2004 Jan; 30(1):91-100.
    View in: PubMed
  177. Haq S, Kilter H, Michael A, Tao J, O'Leary E, Sun XM, Walters B, Bhattacharya K, Chen X, Cui L, Andreucci M, Rosenzweig A, Guerrero JL, Patten R, Liao R, Molkentin J, Picard M, Bonventre JV, Force T. Deletion of cytosolic phospholipase A2 promotes striated muscle growth. Nat Med. 2003 Jul; 9(7):944-51.
    View in: PubMed
  178. Muñoz NM, Kim YJ, Meliton AY, Kim KP, Han SK, Boetticher E, O'Leary E, Myou S, Zhu X, Bonventre JV, Leff AR, Cho W. Human group V phospholipase A2 induces group IVA phospholipase A2-independent cysteinyl leukotriene synthesis in human eosinophils. J Biol Chem. 2003 Oct 3; 278(40):38813-20.
    View in: PubMed
  179. Bonventre JV. Dedifferentiation and proliferation of surviving epithelial cells in acute renal failure. J Am Soc Nephrol. 2003 Jun; 14 Suppl 1:S55-61.
    View in: PubMed
  180. Hung CC, Ichimura T, Stevens JL, Bonventre JV. Protection of renal epithelial cells against oxidative injury by endoplasmic reticulum stress preconditioning is mediated by ERK1/2 activation. J Biol Chem. 2003 Aug 1; 278(31):29317-26.
    View in: PubMed
  181. Li LF, Ouyang B, Choukroun G, Matyal R, Mascarenhas M, Jafari B, Bonventre JV, Force T, Quinn DA. Stretch-induced IL-8 depends on c-Jun NH2-terminal and nuclear factor-kappaB-inducing kinases. Am J Physiol Lung Cell Mol Physiol. 2003 Aug; 285(2):L464-75.
    View in: PubMed
  182. Park KM, Byun JY, Kramers C, Kim JI, Huang PL, Bonventre JV. Inducible nitric-oxide synthase is an important contributor to prolonged protective effects of ischemic preconditioning in the mouse kidney. J Biol Chem. 2003 Jul 18; 278(29):27256-66.
    View in: PubMed
  183. Han WK, Sapirstein A, Hung CC, Alessandrini A, Bonventre JV. Cross-talk between cytosolic phospholipase A2 alpha (cPLA2 alpha) and secretory phospholipase A2 (sPLA2) in hydrogen peroxide-induced arachidonic acid release in murine mesangial cells: sPLA2 regulates cPLA2 alpha activity that is responsible for arachidonic acid release. J Biol Chem. 2003 Jun 27; 278(26):24153-63.
    View in: PubMed
  184. Choi WI, Quinn DA, Park KM, Moufarrej RK, Jafari B, Syrkina O, Bonventre JV, Hales CA. Systemic microvascular leak in an in vivo rat model of ventilator-induced lung injury. Am J Respir Crit Care Med. 2003 Jun 15; 167(12):1627-32.
    View in: PubMed
  185. Cilenti L, Lee Y, Hess S, Srinivasula S, Park KM, Junqueira D, Davis H, Bonventre JV, Alnemri ES, Zervos AS. Characterization of a novel and specific inhibitor for the pro-apoptotic protease Omi/HtrA2. J Biol Chem. 2003 Mar 28; 278(13):11489-94.
    View in: PubMed
  186. Rosenberger TA, Villacreses NE, Contreras MA, Bonventre JV, Rapoport SI. Brain lipid metabolism in the cPLA2 knockout mouse. J Lipid Res. 2003 Jan; 44(1):109-17.
    View in: PubMed
  187. Heyman SN, Lieberthal W, Rogiers P, Bonventre JV. Animal models of acute tubular necrosis. Curr Opin Crit Care. 2002 Dec; 8(6):526-34.
    View in: PubMed
  188. Goruppi S, Bonventre JV, Kyriakis JM. Signaling pathways and late-onset gene induction associated with renal mesangial cell hypertrophy. EMBO J. 2002 Oct 15; 21(20):5427-36.
    View in: PubMed
  189. Bonventre JV. The kidney proteome: a hint of things to come. Kidney Int. 2002 Oct; 62(4):1470-1.
    View in: PubMed
  190. Kuehn EW, Park KM, Somlo S, Bonventre JV. Kidney injury molecule-1 expression in murine polycystic kidney disease. Am J Physiol Renal Physiol. 2002 Dec; 283(6):F1326-36.
    View in: PubMed
  191. Bailly V, Zhang Z, Meier W, Cate R, Sanicola M, Bonventre JV. Shedding of kidney injury molecule-1, a putative adhesion protein involved in renal regeneration. J Biol Chem. 2002 Oct 18; 277(42):39739-48.
    View in: PubMed
  192. Auchincloss H, Bonventre JV. Transplanting cloned cells into therapeutic promise. Nat Biotechnol. 2002 Jul; 20(7):665-6.
    View in: PubMed
  193. Han WK, Bailly V, Abichandani R, Thadhani R, Bonventre JV. Kidney Injury Molecule-1 (KIM-1): a novel biomarker for human renal proximal tubule injury. Kidney Int. 2002 Jul; 62(1):237-44.
    View in: PubMed
  194. Song H, Lim H, Paria BC, Matsumoto H, Swift LL, Morrow J, Bonventre JV, Dey SK. Cytosolic phospholipase A2alpha is crucial [correction of A2alpha deficiency is crucial] for 'on-time' embryo implantation that directs subsequent development. Development. 2002 Jun; 129(12):2879-89.
    View in: PubMed
  195. Ichinose F, Ullrich R, Sapirstein A, Jones RC, Bonventre JV, Serhan CN, Bloch KD, Zapol WM. Cytosolic phospholipase A(2) in hypoxic pulmonary vasoconstriction. J Clin Invest. 2002 Jun; 109(11):1493-500.
    View in: PubMed
  196. Gray ML, Bonventre JV. Training PhD researchers to translate science to clinical medicine: closing the gap from the other side. Nat Med. 2002 May; 8(5):433-6.
    View in: PubMed
  197. Kim SS, Chae HS, Bach JH, Lee MW, Kim KY, Lee WB, Jung YM, Bonventre JV, Suh YH. P53 mediates ceramide-induced apoptosis in SKN-SH cells. Oncogene. 2002 Mar 27; 21(13):2020-8.
    View in: PubMed
  198. Bonventre JV. Daily hemodialysis--will treatment each day improve the outcome in patients with acute renal failure? N Engl J Med. 2002 Jan 31; 346(5):362-4.
    View in: PubMed
  199. Bonventre JV. Kidney ischemic preconditioning. Curr Opin Nephrol Hypertens. 2002 Jan; 11(1):43-8.
    View in: PubMed
  200. Bonventre JV, Sapirstein A. Group IV cytosolic phospholipase A2 (PLA2) function: insights from the knockout mouse. Adv Exp Med Biol. 2002; 507:25-31.
    View in: PubMed
  201. Diaz BL, Fujishima H, Sapirstein A, Bonventre JV, Arm JP. Participation of cytosolic phospholipase A2 in eicosanoid generation by mouse bone marrow-derived mast cells. Adv Exp Med Biol. 2002; 507:41-6.
    View in: PubMed
  202. Park KM, Kramers C, Vayssier-Taussat M, Chen A, Bonventre JV. Prevention of kidney ischemia/reperfusion-induced functional injury, MAPK and MAPK kinase activation, and inflammation by remote transient ureteral obstruction. J Biol Chem. 2002 Jan 18; 277(3):2040-9.
    View in: PubMed
  203. Panini SR, Yang L, Rusinol AE, Sinensky MS, Bonventre JV, Leslie CC. Arachidonate metabolism and the signaling pathway of induction of apoptosis by oxidized LDL/oxysterol. J Lipid Res. 2001 Oct; 42(10):1678-86.
    View in: PubMed
  204. Namura S, Iihara K, Takami S, Nagata I, Kikuchi H, Matsushita K, Moskowitz MA, Bonventre JV, Alessandrini A. Intravenous administration of MEK inhibitor U0126 affords brain protection against forebrain ischemia and focal cerebral ischemia. Proc Natl Acad Sci U S A. 2001 Sep 25; 98(20):11569-74.
    View in: PubMed
  205. Das A, Asatryan L, Reddy MA, Wass CA, Stins MF, Joshi S, Bonventre JV, Kim KS. Differential role of cytosolic phospholipase A2 in the invasion of brain microvascular endothelial cells by Escherichia coli and Listeria monocytogenes. J Infect Dis. 2001 Sep 15; 184(6):732-7.
    View in: PubMed
  206. Bonventre JV. Complement and renal ischemia-reperfusion injury. Am J Kidney Dis. 2001 Aug; 38(2):430-6.
    View in: PubMed
  207. Sheridan AM, Force T, Yoon HJ, O'Leary E, Choukroun G, Taheri MR, Bonventre JV. PLIP, a novel splice variant of Tip60, interacts with group IV cytosolic phospholipase A(2), induces apoptosis, and potentiates prostaglandin production. Mol Cell Biol. 2001 Jul; 21(14):4470-81.
    View in: PubMed
  208. Sheridan AM, Sapirstein A, Lemieux N, Martin BD, Kim DK, Bonventre JV. Nuclear translocation of cytosolic phospholipase A2 is induced by ATP depletion. J Biol Chem. 2001 Aug 10; 276(32):29899-905.
    View in: PubMed
  209. Zuk A, Bonventre JV, Matlin KS. Expression of fibronectin splice variants in the postischemic rat kidney. Am J Physiol Renal Physiol. 2001 Jun; 280(6):F1037-53.
    View in: PubMed
  210. Hsu SI, Yang CM, Sim KG, Hentschel DM, O'Leary E, Bonventre JV. TRIP-Br: a novel family of PHD zinc finger- and bromodomain-interacting proteins that regulate the transcriptional activity of E2F-1/DP-1. EMBO J. 2001 May 1; 20(9):2273-85.
    View in: PubMed
  211. Downey P, Sapirstein A, O'Leary E, Sun TX, Brown D, Bonventre JV. Renal concentrating defect in mice lacking group IV cytosolic phospholipase A(2). Am J Physiol Renal Physiol. 2001 Apr; 280(4):F607-18.
    View in: PubMed
  212. Samad TA, Moore KA, Sapirstein A, Billet S, Allchorne A, Poole S, Bonventre JV, Woolf CJ. Interleukin-1beta-mediated induction of Cox-2 in the CNS contributes to inflammatory pain hypersensitivity. Nature. 2001 Mar 22; 410(6827):471-5.
    View in: PubMed
  213. Hong KH, Bonventre JC, O'Leary E, Bonventre JV, Lander ES. Deletion of cytosolic phospholipase A(2) suppresses Apc(Min)-induced tumorigenesis. Proc Natl Acad Sci U S A. 2001 Mar 27; 98(7):3935-9.
    View in: PubMed
  214. Park KM, Chen A, Bonventre JV. Prevention of kidney ischemia/reperfusion-induced functional injury and JNK, p38, and MAPK kinase activation by remote ischemic pretreatment. J Biol Chem. 2001 Apr 13; 276(15):11870-6.
    View in: PubMed
  215. Sheridan AM, Bonventre JV. Pathophysiology of ischemic acute renal failure. Contrib Nephrol. 2001; (132):7-21.
    View in: PubMed
  216. Sapirstein A, Bonventre JV. Specific physiological roles of cytosolic phospholipase A(2) as defined by gene knockouts. Biochim Biophys Acta. 2000 Oct 31; 1488(1-2):139-48.
    View in: PubMed
  217. Choukroun GJ, Marshansky V, Gustafson CE, McKee M, Hajjar RJ, Rosenzweig A, Brown D, Bonventre JV. Cytosolic phospholipase A(2) regulates golgi structure and modulates intracellular trafficking of membrane proteins. J Clin Invest. 2000 Oct; 106(8):983-93.
    View in: PubMed
  218. Sheridan AM, Bonventre JV. Cell biology and molecular mechanisms of injury in ischemic acute renal failure. Curr Opin Nephrol Hypertens. 2000 Jul; 9(4):427-34.
    View in: PubMed
  219. Gijón MA, Spencer DM, Siddiqi AR, Bonventre JV, Leslie CC. Cytosolic phospholipase A2 is required for macrophage arachidonic acid release by agonists that Do and Do not mobilize calcium. Novel role of mitogen-activated protein kinase pathways in cytosolic phospholipase A2 regulation. J Biol Chem. 2000 Jun 30; 275(26):20146-56.
    View in: PubMed
  220. Makkinje A, Quinn DA, Chen A, Cadilla CL, Force T, Bonventre JV, Kyriakis JM. Gene 33/Mig-6, a transcriptionally inducible adapter protein that binds GTP-Cdc42 and activates SAPK/JNK. A potential marker transcript for chronic pathologic conditions, such as diabetic nephropathy. Possible role in the response to persistent stress. J Biol Chem. 2000 Jun 9; 275(23):17838-47.
    View in: PubMed
  221. Sapirstein A, Bonventre JV. Phospholipases A2 in ischemic and toxic brain injury. Neurochem Res. 2000 May; 25(5):745-53.
    View in: PubMed
  222. Hsu SI, Ramirez SB, Winn MP, Bonventre JV, Owen WF. Evidence for genetic factors in the development and progression of IgA nephropathy. Kidney Int. 2000 May; 57(5):1818-35.
    View in: PubMed
  223. Faccio L, Chen A, Fusco C, Martinotti S, Bonventre JV, Zervos AS. Mxi2, a splice variant of p38 stress-activated kinase, is a distal nephron protein regulated with kidney ischemia. Am J Physiol Cell Physiol. 2000 Apr; 278(4):C781-90.
    View in: PubMed
  224. Welch DR, Sakamaki T, Pioquinto R, Leonard TO, Goldberg SF, Hon Q, Erikson RL, Rieber M, Rieber MS, Hicks DJ, Bonventre JV, Alessandrini A. Transfection of constitutively active mitogen-activated protein/extracellular signal-regulated kinase kinase confers tumorigenic and metastatic potentials to NIH3T3 cells. Cancer Res. 2000 Mar 15; 60(6):1552-6.
    View in: PubMed
  225. Faccio L, Fusco C, Chen A, Martinotti S, Bonventre JV, Zervos AS. Characterization of a novel human serine protease that has extensive homology to bacterial heat shock endoprotease HtrA and is regulated by kidney ischemia. J Biol Chem. 2000 Jan 28; 275(4):2581-8.
    View in: PubMed
  226. Tekki-Kessaris N, Bonventre JV, Boulter CA. Characterization of the mouse Kid1 gene and identification of a highly related gene, Kid2. Gene. 1999 Nov 15; 240(1):13-22.
    View in: PubMed
  227. Mallouk Y, Vayssier-Taussat M, Bonventre JV, Polla BS. Heat shock protein 70 and ATP as partners in cell homeostasis (Review). Int J Mol Med. 1999 Nov; 4(5):463-74.
    View in: PubMed
  228. Alessandrini A, Namura S, Moskowitz MA, Bonventre JV. MEK1 protein kinase inhibition protects against damage resulting from focal cerebral ischemia. Proc Natl Acad Sci U S A. 1999 Oct 26; 96(22):12866-9.
    View in: PubMed
  229. Fukuda T, Kim DK, Chin MR, Hales CA, Bonventre JV. Increased group IV cytosolic phospholipase A2 activity in lungs of sheep after smoke inhalation injury. Am J Physiol. 1999 Sep; 277(3 Pt 1):L533-42.
    View in: PubMed
  230. Kelly KJ, Meehan SM, Colvin RB, Williams WW, Bonventre JV. Protection from toxicant-mediated renal injury in the rat with anti-CD54 antibody. Kidney Int. 1999 Sep; 56(3):922-31.
    View in: PubMed
  231. Abbate M, Brown D, Bonventre JV. Expression of NCAM recapitulates tubulogenic development in kidneys recovering from acute ischemia. Am J Physiol. 1999 Sep; 277(3 Pt 2):F454-63.
    View in: PubMed
  232. Rabb H, Bonventre JV. Leukocyte adhesion molecules in transplantation. Am J Med. 1999 Aug; 107(2):157-65.
    View in: PubMed
  233. Quinn D, Tager A, Joseph PM, Bonventre JV, Force T, Hales CA. Stretch-induced mitogen-activated protein kinase activation and interleukin-8 production in type II alveolar cells. Chest. 1999 Jul; 116(1 Suppl):89S-90S.
    View in: PubMed
  234. Fujishima H, Sanchez Mejia RO, Bingham CO, Lam BK, Sapirstein A, Bonventre JV, Austen KF, Arm JP. Cytosolic phospholipase A2 is essential for both the immediate and the delayed phases of eicosanoid generation in mouse bone marrow-derived mast cells. Proc Natl Acad Sci U S A. 1999 Apr 27; 96(9):4803-7.
    View in: PubMed
  235. Huang Z, Philippin B, O'Leary E, Bonventre JV, Kriz W, Witzgall R. Expression of the transcriptional repressor protein Kid-1 leads to the disintegration of the nucleolus. J Biol Chem. 1999 Mar 19; 274(12):7640-8.
    View in: PubMed
  236. Bonventre JV. The 85-kD cytosolic phospholipase A2 knockout mouse: a new tool for physiology and cell biology. J Am Soc Nephrol. 1999 Feb; 10(2):404-12.
    View in: PubMed
  237. Witzgall R, Obermüller N, Bölitz U, Calvet JP, Cowley BD, Walker C, Kriz W, Gretz N, Bonventre JV. Kid-1 expression is high in differentiated renal proximal tubule cells and suppressed in cyst epithelia. Am J Physiol. 1998 Dec; 275(6 Pt 2):F928-37.
    View in: PubMed
  238. Klivenyi P, Beal MF, Ferrante RJ, Andreassen OA, Wermer M, Chin MR, Bonventre JV. Mice deficient in group IV cytosolic phospholipase A2 are resistant to MPTP neurotoxicity. J Neurochem. 1998 Dec; 71(6):2634-7.
    View in: PubMed
  239. Choukroun G, Hajjar R, Kyriakis JM, Bonventre JV, Rosenzweig A, Force T. Role of the stress-activated protein kinases in endothelin-induced cardiomyocyte hypertrophy. J Clin Invest. 1998 Oct 1; 102(7):1311-20.
    View in: PubMed
  240. Zuk A, Bonventre JV, Brown D, Matlin KS. Polarity, integrin, and extracellular matrix dynamics in the postischemic rat kidney. Am J Physiol. 1998 Sep; 275(3 Pt 1):C711-31.
    View in: PubMed
  241. Bonventre JV, Force T. Mitogen-activated protein kinases and transcriptional responses in renal injury and repair. Curr Opin Nephrol Hypertens. 1998 Jul; 7(4):425-33.
    View in: PubMed
  242. Ichimura T, Bonventre JV, Bailly V, Wei H, Hession CA, Cate RL, Sanicola M. Kidney injury molecule-1 (KIM-1), a putative epithelial cell adhesion molecule containing a novel immunoglobulin domain, is up-regulated in renal cells after injury. J Biol Chem. 1998 Feb 13; 273(7):4135-42.
    View in: PubMed
  243. Bonventre J. [Role of adhesion molecules in acute ischemic renal insufficiency]. Nephrologie. 1998; 19(2):57-8.
    View in: PubMed
  244. Bonventre JV. Pathogenetic and regenerative mechanisms in acute tubular necrosis. Kidney Blood Press Res. 1998; 21(2-4):226-9.
    View in: PubMed
  245. Force T, Bonventre JV. Growth factors and mitogen-activated protein kinases. Hypertension. 1998 Jan; 31(1 Pt 2):152-61.
    View in: PubMed
  246. Bonventre JV, Huang Z, Taheri MR, O'Leary E, Li E, Moskowitz MA, Sapirstein A. Reduced fertility and postischaemic brain injury in mice deficient in cytosolic phospholipase A2. Nature. 1997 Dec 11; 390(6660):622-5.
    View in: PubMed
  247. Brown D, Lee R, Bonventre JV. Redistribution of villin to proximal tubule basolateral membranes after ischemia and reperfusion. Am J Physiol. 1997 Dec; 273(6 Pt 2):F1003-12.
    View in: PubMed
  248. Pombo CM, Tsujita T, Kyriakis JM, Bonventre JV, Force T. Activation of the Ste20-like oxidant stress response kinase-1 during the initial stages of chemical anoxia-induced necrotic cell death. Requirement for dual inputs of oxidant stress and increased cytosolic [Ca2+]. J Biol Chem. 1997 Nov 14; 272(46):29372-9.
    View in: PubMed
  249. Elser B, Kriz W, Bonventre JV, Englert C, Witzgall R. The Krüppel-associated box (KRAB)-zinc finger protein Kid-1 and the Wilms' tumor protein WT1, two transcriptional repressor proteins, bind to heteroduplex DNA. J Biol Chem. 1997 Oct 31; 272(44):27908-12.
    View in: PubMed
  250. Bonventre JV. Roles of phospholipases A2 in brain cell and tissue injury associated with ischemia and excitotoxicity. J Lipid Mediat Cell Signal. 1997 Sep; 17(1):71-9.
    View in: PubMed
  251. Bonventre JV. Roles of phospholipases A2 in brain cell and tissue injury associated with ischemia and excitotoxicity. J Lipid Mediat Cell Signal. 1997 Jul; 16(3):199-208.
    View in: PubMed
  252. DuBose TD, Warnock DG, Mehta RL, Bonventre JV, Hammerman MR, Molitoris BA, Paller MS, Siegel NJ, Scherbenske J, Striker GE. Acute renal failure in the 21st century: recommendations for management and outcomes assessment. Am J Kidney Dis. 1997 May; 29(5):793-9.
    View in: PubMed
  253. Chertow GM, Burke SK, Lazarus JM, Stenzel KH, Wombolt D, Goldberg D, Bonventre JV, Slatopolsky E. Poly[allylamine hydrochloride] (RenaGel): a noncalcemic phosphate binder for the treatment of hyperphosphatemia in chronic renal failure. Am J Kidney Dis. 1997 Jan; 29(1):66-71.
    View in: PubMed
  254. Kim SS, Chen YM, O'Leary E, Witzgall R, Vidal M, Bonventre JV. A novel member of the RING finger family, KRIP-1, associates with the KRAB-A transcriptional repressor domain of zinc finger proteins. Proc Natl Acad Sci U S A. 1996 Dec 24; 93(26):15299-304.
    View in: PubMed
  255. Kelly KJ, Tolkoff-Rubin NE, Rubin RH, Williams WW, Meehan SM, Meschter CL, Christenson JG, Bonventre JV. An oral platelet-activating factor antagonist, Ro-24-4736, protects the rat kidney from ischemic injury. Am J Physiol. 1996 Nov; 271(5 Pt 2):F1061-7.
    View in: PubMed
  256. Pombo CM, Bonventre JV, Molnar A, Kyriakis J, Force T. Activation of a human Ste20-like kinase by oxidant stress defines a novel stress response pathway. EMBO J. 1996 Sep 2; 15(17):4537-46.
    View in: PubMed
  257. Bonventre JV. Roles of phospholipases A2 in brain cell and tissue injury associated with ischemia and excitotoxicity. J Lipid Mediat Cell Signal. 1996 Sep; 14(1-3):15-23.
    View in: PubMed
  258. Sapirstein A, Spech RA, Witzgall R, Bonventre JV. Cytosolic phospholipase A2 (PLA2), but not secretory PLA2, potentiates hydrogen peroxide cytotoxicity in kidney epithelial cells. J Biol Chem. 1996 Aug 30; 271(35):21505-13.
    View in: PubMed
  259. Force T, Pombo CM, Avruch JA, Bonventre JV, Kyriakis JM. Stress-activated protein kinases in cardiovascular disease. Circ Res. 1996 Jun; 78(6):947-53.
    View in: PubMed
  260. Thadhani R, Pascual M, Bonventre JV. Acute renal failure. N Engl J Med. 1996 May 30; 334(22):1448-60.
    View in: PubMed
  261. Rothenberg ME, Ownbey R, Mehlhop PD, Loiselle PM, van de Rijn M, Bonventre JV, Oettgen HC, Leder P, Luster AD. Eotaxin triggers eosinophil-selective chemotaxis and calcium flux via a distinct receptor and induces pulmonary eosinophilia in the presence of interleukin 5 in mice. Mol Med. 1996 May; 2(3):334-48.
    View in: PubMed
  262. Bonventre JV, Colvin RB. Adhesion molecules in renal disease. Curr Opin Nephrol Hypertens. 1996 May; 5(3):254-61.
    View in: PubMed
  263. Kelly KJ, Williams WW, Colvin RB, Meehan SM, Springer TA, Gutierrez-Ramos JC, Bonventre JV. Intercellular adhesion molecule-1-deficient mice are protected against ischemic renal injury. J Clin Invest. 1996 Feb 15; 97(4):1056-63.
    View in: PubMed
  264. Dahlberg CG, Thompson BT, Joseph PM, Garg HG, Spence CR, Quinn DA, Bonventre JV, Hales CA. Differential effect of three commercial heparins on Na+/H+ exchange and growth of PASMC. Am J Physiol. 1996 Feb; 270(2 Pt 1):L260-5.
    View in: PubMed
  265. Bonventre JV, Kelly KJ. Adhesion molecules and acute renal failure. Adv Nephrol Necker Hosp. 1996; 25:159-76.
    View in: PubMed
  266. Bonventre JV. Calcium and calcium-related signalling pathways in glomerular mesangial cells. Clin Exp Pharmacol Physiol. 1996 Jan; 23(1):65-70.
    View in: PubMed
  267. Bonventre JV, Kyriakis JM, Spech R, Witzgall R, Force T. Phospholipase A(2) and Lipids as Potential Modulators of c-Raf-1 Kinase. Am J Ther. 1996 Apr; 3(4):287-293.
    View in: PubMed
  268. Morooka H, Bonventre JV, Pombo CM, Kyriakis JM, Force T. Ischemia and reperfusion enhance ATF-2 and c-Jun binding to cAMP response elements and to an AP-1 binding site from the c-jun promoter. J Biol Chem. 1995 Dec 15; 270(50):30084-92.
    View in: PubMed
  269. Silverman ES, Thompson BT, Quinn DA, Kinane TB, Bonventre JV, Hales CA. Na+/H+ exchange in pulmonary artery smooth muscle from spontaneously hypertensive and Wistar-Kyoto rats. Am J Physiol. 1995 Nov; 269(5 Pt 1):L673-80.
    View in: PubMed
  270. Kim DK, Rordorf G, Nemenoff RA, Koroshetz WJ, Bonventre JV. Glutamate stably enhances the activity of two cytosolic forms of phospholipase A2 in brain cortical cultures. Biochem J. 1995 Aug 15; 310 ( Pt 1):83-90.
    View in: PubMed
  271. Kim DK, Fukuda T, Thompson BT, Cockrill B, Hales C, Bonventre JV. Bronchoalveolar lavage fluid phospholipase A2 activities are increased in human adult respiratory distress syndrome. Am J Physiol. 1995 Jul; 269(1 Pt 1):L109-18.
    View in: PubMed
  272. Rabb H, Mendiola CC, Saba SR, Dietz JR, Smith CW, Bonventre JV, Ramirez G. Antibodies to ICAM-1 protect kidneys in severe ischemic reperfusion injury. Biochem Biophys Res Commun. 1995 Jun 6; 211(1):67-73.
    View in: PubMed
  273. Bonventre JV, Witzgall R. Kid-1, a kidney transcription factor. Exp Nephrol. 1995 May-Jun; 3(3):159-64.
    View in: PubMed
  274. Ross BM, Kim DK, Bonventre JV, Kish SJ. Characterization of a novel phospholipase A2 activity in human brain. J Neurochem. 1995 May; 64(5):2213-21.
    View in: PubMed
  275. Kleinman JG, Worcester EM, Beshensky AM, Sheridan AM, Bonventre JV, Brown D. Upregulation of osteopontin expression by ischemia in rat kidney. Ann N Y Acad Sci. 1995 Apr 21; 760:321-3.
    View in: PubMed
  276. Nakamura H, Kim DK, Philbin DM, Peterson MB, Debros F, Koski G, Bonventre JV. Heparin-enhanced plasma phospholipase A2 activity and prostacyclin synthesis in patients undergoing cardiac surgery. J Clin Invest. 1995 Mar; 95(3):1062-70.
    View in: PubMed
  277. Rabb H, Mendiola CC, Dietz J, Saba SR, Issekutz TB, Abanilla F, Bonventre JV, Ramirez G. Role of CD11a and CD11b in ischemic acute renal failure in rats. Am J Physiol. 1994 Dec; 267(6 Pt 2):F1052-8.
    View in: PubMed
  278. Witzgall R, O'Leary E, Bonventre JV. A mammalian expression vector for the expression of GAL4 fusion proteins with an epitope tag and histidine tail. Anal Biochem. 1994 Dec; 223(2):291-8.
    View in: PubMed
  279. Abbate M, Bonventre JV, Brown D. The microtubule network of renal epithelial cells is disrupted by ischemia and reperfusion. Am J Physiol. 1994 Dec; 267(6 Pt 2):F971-8.
    View in: PubMed
  280. Koroshetz WJ, Bonventre JV. Heat shock response in the central nervous system. Experientia. 1994 Nov 30; 50(11-12):1085-91.
    View in: PubMed
  281. Pombo CM, Bonventre JV, Avruch J, Woodgett JR, Kyriakis JM, Force T. The stress-activated protein kinases are major c-Jun amino-terminal kinases activated by ischemia and reperfusion. J Biol Chem. 1994 Oct 21; 269(42):26546-51.
    View in: PubMed
  282. Sohn UD, Kim DK, Bonventre JV, Behar J, Biancani P. Role of 100-kDa cytosolic PLA2 in ACh-induced contraction of cat esophageal circular muscle. Am J Physiol. 1994 Sep; 267(3 Pt 1):G433-41.
    View in: PubMed
  283. Witzgall R, O'Leary E, Leaf A, Onaldi D, Bonventre JV. The Krüppel-associated box-A (KRAB-A) domain of zinc finger proteins mediates transcriptional repression. Proc Natl Acad Sci U S A. 1994 May 10; 91(10):4514-8.
    View in: PubMed
  284. Balendiran K, Bonventre J, Knott R, Jack W, Benner J, Schildkraut I, Anderson JE. Expression, purification, and crystallization of restriction endonuclease PvuII with DNA containing its recognition site. Proteins. 1994 May; 19(1):77-9.
    View in: PubMed
  285. Witzgall R, Brown D, Schwarz C, Bonventre JV. Localization of proliferating cell nuclear antigen, vimentin, c-Fos, and clusterin in the postischemic kidney. Evidence for a heterogenous genetic response among nephron segments, and a large pool of mitotically active and dedifferentiated cells. J Clin Invest. 1994 May; 93(5):2175-88.
    View in: PubMed
  286. Witzgall R, Volk R, Yeung RS, Bonventre JV. Genomic structure and chromosomal location of the rat gene encoding the zinc finger transcription factor Kid-1. Genomics. 1994 Mar 15; 20(2):203-9.
    View in: PubMed
  287. Force T, Bonventre JV, Heidecker G, Rapp U, Avruch J, Kyriakis JM. Enzymatic characteristics of the c-Raf-1 protein kinase. Proc Natl Acad Sci U S A. 1994 Feb 15; 91(4):1270-4.
    View in: PubMed
  288. Kelly KJ, Williams WW, Colvin RB, Bonventre JV. Antibody to intercellular adhesion molecule 1 protects the kidney against ischemic injury. Proc Natl Acad Sci U S A. 1994 Jan 18; 91(2):812-6.
    View in: PubMed
  289. Lovis C, Mach F, Donati YR, Bonventre JV, Polla BS. Heat shock proteins and the kidney. Ren Fail. 1994; 16(2):179-92.
    View in: PubMed
  290. Kim DK, Bonventre JV. Purification of a 100 kDa phospholipase A2 from spleen, lung and kidney: antiserum raised to pig spleen phospholipase A2 recognizes a similar form in bovine lung, kidney and platelets, and immunoprecipitates phospholipase A2 activity. Biochem J. 1993 Aug 15; 294 ( Pt 1):261-70.
    View in: PubMed
  291. Kyriakis JM, Force TL, Rapp UR, Bonventre JV, Avruch J. Mitogen regulation of c-Raf-1 protein kinase activity toward mitogen-activated protein kinase-kinase. J Biol Chem. 1993 Jul 25; 268(21):16009-19.
    View in: PubMed
  292. Bonventre JV. Mechanisms of ischemic acute renal failure. Kidney Int. 1993 May; 43(5):1160-78.
    View in: PubMed
  293. Cantiello HF, Prat AG, Bonventre JV, Cunningham CC, Hartwig JH, Ausiello DA. Actin-binding protein contributes to cell volume regulatory ion channel activation in melanoma cells. J Biol Chem. 1993 Mar 5; 268(7):4596-9.
    View in: PubMed
  294. Bonventre JV, Koroshetz WJ. Phospholipase A2 (PLA2) activity in gerbil brain: characterization of cytosolic and membrane-associated forms and effects of ischemia and reperfusion on enzymatic activity. J Lipid Mediat. 1993 Mar-Apr; 6(1-3):457-71.
    View in: PubMed
  295. Witzgall R, O'Leary E, Gessner R, Ouellette AJ, Bonventre JV. Kid-1, a putative renal transcription factor: regulation during ontogeny and in response to ischemia and toxic injury. Mol Cell Biol. 1993 Mar; 13(3):1933-42.
    View in: PubMed
  296. Wong JT, Bonventre JV, Dunn S, Colvin RB. Comparative studies of isolated CD3: CD8, CD3: CD3, and monovalent CD3 binding on CD8+ T-cell activation: model of progressive T-cell receptor aggregation synergism. Hum Immunol. 1992 Nov; 35(3):200-8.
    View in: PubMed
  297. Bonventre JV. Phospholipase A2 and signal transduction. J Am Soc Nephrol. 1992 Aug; 3(2):128-50.
    View in: PubMed
  298. Force T, Bonventre JV, Flannery MR, Gorn AH, Yamin M, Goldring SR. A cloned porcine renal calcitonin receptor couples to adenylyl cyclase and phospholipase C. Am J Physiol. 1992 Jun; 262(6 Pt 2):F1110-5.
    View in: PubMed
  299. Abou-Samra AB, Jüppner H, Force T, Freeman MW, Kong XF, Schipani E, Urena P, Richards J, Bonventre JV, Potts JT, et al. Expression cloning of a common receptor for parathyroid hormone and parathyroid hormone-related peptide from rat osteoblast-like cells: a single receptor stimulates intracellular accumulation of both cAMP and inositol trisphosphates and increases intracellular free calcium. Proc Natl Acad Sci U S A. 1992 Apr 1; 89(7):2732-6.
    View in: PubMed
  300. Sellmayer A, Krane SM, Ouellette AJ, Bonventre JV. 1 alpha,25-(OH)2 vitamin D3 enhances expression of the genes encoding Ca(2+)-binding proteins MRP-8 and MRP-14. Am J Physiol. 1992 Jan; 262(1 Pt 1):C235-42.
    View in: PubMed
  301. Bonventre JV, Weinberg JM. Kidney preservation ex vivo for transplantation. Annu Rev Med. 1992; 43:523-53.
    View in: PubMed
  302. Rordorf G, Koroshetz WJ, Bonventre JV. Heat shock protects cultured neurons from glutamate toxicity. Neuron. 1991 Dec; 7(6):1043-51.
    View in: PubMed
  303. Hajjar RJ, Bonventre JV. Oscillations of intracellular calcium induced by vasopressin in individual fura-2-loaded mesangial cells. Frequency dependence on basal calcium concentration, agonist concentration, and temperature. J Biol Chem. 1991 Nov 15; 266(32):21589-94.
    View in: PubMed
  304. Malis CD, Leaf A, Varadarajan GS, Newell JB, Weber PC, Force T, Bonventre JV. Effects of dietary omega 3 fatty acids on vascular contractility in preanoxic and postanoxic aortic rings. Circulation. 1991 Sep; 84(3):1393-401.
    View in: PubMed
  305. Rordorf G, Uemura Y, Bonventre JV. Characterization of phospholipase A2 (PLA2) activity in gerbil brain: enhanced activities of cytosolic, mitochondrial, and microsomal forms after ischemia and reperfusion. J Neurosci. 1991 Jun; 11(6):1829-36.
    View in: PubMed
  306. Nakamura H, Nemenoff RA, Gronich JH, Bonventre JV. Subcellular characteristics of phospholipase A2 activity in the rat kidney. Enhanced cytosolic, mitochondrial, and microsomal phospholipase A2 enzymatic activity after renal ischemia and reperfusion. J Clin Invest. 1991 May; 87(5):1810-8.
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  307. Force T, Kyriakis JM, Avruch J, Bonventre JV. Endothelin, vasopressin, and angiotensin II enhance tyrosine phosphorylation by protein kinase C-dependent and -independent pathways in glomerular mesangial cells. J Biol Chem. 1991 Apr 5; 266(10):6650-6.
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  308. Force T, Hyman G, Hajjar R, Sellmayer A, Bonventre JV. Noncyclooxygenase metabolites of arachidonic acid amplify the vasopressin-induced Ca2+ signal in glomerular mesangial cells by releasing Ca2+ from intracellular stores. J Biol Chem. 1991 Mar 5; 266(7):4295-302.
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  309. Bonventre JV, Nemenoff R. Renal tubular arachidonic acid metabolism. Kidney Int. 1991 Mar; 39(3):438-49.
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  310. Bonventre JV, Sukhatme VP, Bamberger M, Ouellette AJ, Brown D. Localization of the protein product of the immediate early growth response gene, Egr-1, in the kidney after ischemia and reperfusion. Cell Regul. 1991 Mar; 2(3):251-60.
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  311. Sellmayer A, Uedelhoven WM, Weber PC, Bonventre JV. Endogenous non-cyclooxygenase metabolites of arachidonic acid modulate growth and mRNA levels of immediate-early response genes in rat mesangial cells. J Biol Chem. 1991 Feb 25; 266(6):3800-7.
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  312. Polla BS, Mili N, Donati YR, Bonventre JV. [Heat-shock proteins: what implications in nephrology?]. Nephrologie. 1991; 12(3):119-23.
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  313. Malis CD, Weber PC, Leaf A, Bonventre JV. Incorporation of marine lipids into mitochondrial membranes increases susceptibility to damage by calcium and reactive oxygen species: evidence for enhanced activation of phospholipase A2 in mitochondria enriched with n-3 fatty acids. Proc Natl Acad Sci U S A. 1990 Nov; 87(22):8845-9.
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  314. Cybulsky AV, Bonventre JV, Quigg RJ, Lieberthal W, Salant DJ. Cytosolic calcium and protein kinase C reduce complement-mediated glomerular epithelial injury. Kidney Int. 1990 Nov; 38(5):803-11.
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  315. Sugiyama E, Cantagrel A, Reno T, Stafford-Brady F, Yeh ET, Bonventre JV. Selection of T cell receptor expression mutants through the functionally linked Ly-6A. Cell Immunol. 1990 Oct 15; 130(2):271-80.
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  316. Gronich JH, Bonventre JV, Nemenoff RA. Purification of a high-molecular-mass form of phospholipase A2 from rat kidney activated at physiological calcium concentrations. Biochem J. 1990 Oct 1; 271(1):37-43.
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  317. Cybulsky AV, Bonventre JV, Quigg RJ, Wolfe LS, Salant DJ. Extracellular matrix regulates proliferation and phospholipid turnover in glomerular epithelial cells. Am J Physiol. 1990 Aug; 259(2 Pt 2):F326-37.
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  318. Reno TA, Ley S, Sugiyama E, Cantagrel A, Blumberg R, Bonventre J, Terhorst C, Yeh ET. Defects in signal transduction caused by a T cell receptor beta chain substitution. Eur J Immunol. 1990 Jul; 20(7):1417-22.
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  319. Kantengwa S, Capponi AM, Bonventre JV, Polla BS. Calcium and the heat-shock response in the human monocytic line U-937. Am J Physiol. 1990 Jul; 259(1 Pt 1):C77-83.
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  320. Bonventre JV, Gronich JH, Nemenoff RA. Epidermal growth factor enhances glomerular mesangial cell soluble phospholipase A2 activity. J Biol Chem. 1990 Mar 25; 265(9):4934-8.
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  321. Ouellette AJ, Malt RA, Sukhatme VP, Bonventre JV. Expression of two "immediate early" genes, Egr-1 and c-fos, in response to renal ischemia and during compensatory renal hypertrophy in mice. J Clin Invest. 1990 Mar; 85(3):766-71.
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  322. Bonventre JV. Calcium in renal cells. Modulation of calcium-dependent activation of phospholipase A2. Environ Health Perspect. 1990 Mar; 84:155-62.
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  323. Krane SM, Polla BS, Bonventre JV. 1,25-Dihydroxyvitamin D3 increases the toxicity of hydrogen peroxide: the role of calcium and heat shock. Exp Gerontol. 1990; 25(3-4):239-45.
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  324. Bloch DB, Bonventre JV, Neer EJ, Seidman JG. The G protein alpha o subunit alters morphology, growth kinetics, and phospholipid metabolism of somatic cells. Mol Cell Biol. 1989 Dec; 9(12):5434-9.
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  325. Cybulsky AV, Salant DJ, Quigg RJ, Badalamenti J, Bonventre JV. Complement C5b-9 complex activates phospholipases in glomerular epithelial cells. Am J Physiol. 1989 Nov; 257(5 Pt 2):F826-36.
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  326. Stafford-Brady F, Sugiyama E, Robinson DR, Sy MS, Bonventre JV, Yeh ET. Defective signal transduction in CD4-CD8- T cells of lpr mice. Cell Immunol. 1989 Oct 15; 123(2):396-404.
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  327. Force T, Malis CD, Guerrero JL, Varadarajan GS, Bonventre JV, Weber PC, Leaf A. n-3 fatty acids increase postischemic blood flow but do not reduce myocardial necrosis. Am J Physiol. 1989 Oct; 257(4 Pt 2):H1204-10.
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  328. Gronich JH, Bonventre JV, Nemenoff RA. Identification and characterization of a hormonally regulated form of phospholipase A2 in rat renal mesangial cells. J Biol Chem. 1988 Nov 15; 263(32):16645-51.
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  329. Tolkoff-Rubin NE, Rubin RH, Bonventre JV. Noninvasive renal diagnostic studies. Clin Lab Med. 1988 Sep; 8(3):507-26.
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  330. Bonventre JV, Swidler M. Calcium dependency of prostaglandin E2 production in rat glomerular mesangial cells. Evidence that protein kinase C modulates the Ca2+-dependent activation of phospholipase A2. J Clin Invest. 1988 Jul; 82(1):168-76.
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  331. Polla BS, Bonventre JV, Krane SM. 1,25-Dihydroxyvitamin D3 increases the toxicity of hydrogen peroxide in the human monocytic line U937: the role of calcium and heat shock. J Cell Biol. 1988 Jul; 107(1):373-80.
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  332. Margolis BL, Bonventre JV, Kremer SG, Kudlow JE, Skorecki KL. Epidermal growth factor is synergistic with phorbol esters and vasopressin in stimulating arachidonate release and prostaglandin production in renal glomerular mesangial cells. Biochem J. 1988 Jan 15; 249(2):587-92.
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  333. Bonventre JV, Weber PC, Gronich JH. PAF and PDGF increase cytosolic [Ca2+] and phospholipase activity in mesangial cells. Am J Physiol. 1988 Jan; 254(1 Pt 2):F87-94.
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  334. Malis CD, Bonventre JV. Susceptibility of mitochondrial membranes to calcium and reactive oxygen species: implications for ischemic and toxic tissue damage. Prog Clin Biol Res. 1988; 282:235-59.
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  335. Corwin HL, Bonventre JV. Acute renal failure in the intensive care unit. Part 1. Intensive Care Med. 1988; 14(1):10-6.
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  336. Polla BS, Ohara J, Paul WE, Nabavi N, Myer A, Liou HC, Shen FW, Gillis S, Bonventre JV, Glimcher LH, et al. Differential induction of class II gene expression in murine pre-B-cell lines by B-cell stimulatory factor-1 and by antibodies to B-cell surface antigens. J Mol Cell Immunol. 1988; 3(6):363-73.
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  337. Bonventre JV. Mediators of ischemic renal injury. Annu Rev Med. 1988; 39:531-44.
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  338. Corwin HL, Bonventre JV. Acute renal failure in the intensive care unit. Part 2. Intensive Care Med. 1988; 14(2):86-96.
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  339. Ara G, Aprille JR, Malis CD, Kane SB, Cincotta L, Foley J, Bonventre JV, Oseroff AR. Mechanisms of mitochondrial photosensitization by the cationic dye, N,N-bis(2-ethyl-1,3-dioxylene)kryptocyanine (EDKC): preferential inactivation of complex I in the electron transport chain. Cancer Res. 1987 Dec 15; 47(24 Pt 1):6580-5.
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  340. Cheung JY, Constantine JM, Bonventre JV. Cytosolic free calcium concentration and glucose transport in isolated cardiac myocytes. Am J Physiol. 1987 Feb; 252(2 Pt 1):C163-72.
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  341. Ausiello DA, Skorecki KL, Verkman AS, Bonventre JV. Vasopressin signaling in kidney cells. Kidney Int. 1987 Feb; 31(2):521-9.
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  342. Corwin HL, Teplick RS, Schreiber MJ, Fang LS, Bonventre JV, Coggins CH. Prediction of outcome in acute renal failure. Am J Nephrol. 1987; 7(1):8-12.
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  343. Malis CD, Bonventre JV. Mechanism of calcium potentiation of oxygen free radical injury to renal mitochondria. A model for post-ischemic and toxic mitochondrial damage. J Biol Chem. 1986 Oct 25; 261(30):14201-8.
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  344. Cheung JY, Constantine JM, Bonventre JV. Regulation of cytosolic free calcium concentration in cultured renal epithelial cells. Am J Physiol. 1986 Oct; 251(4 Pt 2):F690-701.
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  345. Corwin HL, Bonventre JV. Acute renal failure. Med Clin North Am. 1986 Sep; 70(5):1037-54.
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  346. Bonventre JV, Skorecki KL, Kreisberg JI, Cheung JY. Vasopressin increases cytosolic free calcium concentration in glomerular mesangial cells. Am J Physiol. 1986 Jul; 251(1 Pt 2):F94-102.
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  347. Cheung JY, Bonventre JV, Malis CD, Leaf A. Calcium and ischemic injury. N Engl J Med. 1986 Jun 26; 314(26):1670-6.
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  348. Diamond JR, Bonventre JV, Karnovsky MJ. A role for oxygen free radicals in aminonucleoside nephrosis. Kidney Int. 1986 Feb; 29(2):478-83.
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  349. Bonventre JV, Cheung JY. Cytosolic free calcium concentration in cultured renal epithelial cells. Am J Physiol. 1986 Feb; 250(2 Pt 2):F329-38.
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  350. Cheung JY, Leaf A, Bonventre JV. Mitochondrial function and intracellular calcium in anoxic cardiac myocytes. Am J Physiol. 1986 Jan; 250(1 Pt 1):C18-25.
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  351. Bonventre JV, Cheung JY. Effects of metabolic acidosis on viability of cells exposed to anoxia. Am J Physiol. 1985 Jul; 249(1 Pt 1):C149-59.
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  352. Cheung JY, Leaf A, Bonventre JV. Determination of isolated myocyte viability: staining methods and functional criteria. Basic Res Cardiol. 1985; 80 Suppl 1:23-9.
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  353. Corwin HL, Bonventre JV. Renal insufficiency associated with nonsteroidal anti-inflammatory agents. Am J Kidney Dis. 1984 Sep; 4(2):147-52.
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  354. Blackshear PJ, Nemenoff RA, Bonventre JV, Cheung JY, Avruch J. Hormonal regulation of protein phosphorylation in isolated rat heart cells. Am J Physiol. 1984 May; 246(5 Pt 1):C439-49.
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  355. Cheung JY, Leaf A, Bonventre JV. Mechanism of protection by verapamil and nifedipine from anoxic injury in isolated cardiac myocytes. Am J Physiol. 1984 Mar; 246(3 Pt 1):C323-9.
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  356. Malis CD, Cheung JY, Leaf A, Bonventre JV. Effects of verapamil in models of ischemic acute renal failure in the rat. Am J Physiol. 1983 Dec; 245(6):F735-42.
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  357. Lebowitz PW, Cote ME, Daniels AL, Bonventre JV. Comparative renal effects of midazolam and thiopental in humans. Anesthesiology. 1983 Nov; 59(5):381-4.
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  358. Cheung JY, Thompson IG, Bonventre JV. Effects of extracellular calcium removal and anoxia on isolated rat myocytes. Am J Physiol. 1982 Sep; 243(3):C184-90.
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  359. Jensen SR, Novelline RA, Brewster DC, Bonventre JV. Transient renal artery stenosis produced by a pheochromocytoma. Radiology. 1982 Sep; 144(4):767-8.
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  360. Bonventre JV, Leaf A. Sodium homeostasis: steady states without a set point. Kidney Int. 1982 Jun; 21(6):880-3.
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  361. Roman RJ, Bonventre JV, Silva P, Lechene C. Sodium orthovanadate diuresis in rats. J Pharmacol Exp Ther. 1981 Jul; 218(1):168-74.
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  362. Bonventre JV, Roman RJ, Lechene C. Effect of urea concentration of pelvic fluid on renal concentrating ability. Am J Physiol. 1980 Dec; 239(6):F609-18.
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  363. Bonventre JV, Lechene C. Renal medullary concentrating process: an integrative hypothesis. Am J Physiol. 1980 Dec; 239(6):F578-88.
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  364. Roman RJ, Bonventre JV, Lechene CP. Fluorometric assay for urea in urine, plasma, and tubular fluid. Anal Biochem. 1979 Sep 15; 98(1):136-41.
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  365. Bonventre JV, Karnovsky MJ, Lechene CP. Renal papillary epithelial morphology in antidiuresis and water diuresis. Am J Physiol. 1978 Jul; 235(1):F69-76.
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  366. Beeuwkes R, Bonventre JV. Tubular organization and vascular-tubular relations in the dog kidney. Am J Physiol. 1975 Sep; 229(3):695-713.
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