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Frank H. Guenther, PH.D.

TitleMember of the Affiliated Faculty of the Harvard-MIT Division of Health Sciences and Technology
InstitutionMassachusetts Institute of Technology
DepartmentHealth Sciences and Technology
AddressBoston University
Dept. of Cognitive & Neural Systems
677 Beacon St.
Cambridge MA 02139
Phone617/353-5965

 Bibliographic 
 selected publications
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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  1. Peeva MG, Tourville JA, Agam Y, Holland B, Manoach DS, Guenther FH. White matter impairment in the speech network of individuals with autism spectrum disorder. Neuroimage Clin. 2013; 3:234-41.
    View in: PubMed
  2. Civier O, Bullock D, Max L, Guenther FH. Computational modeling of stuttering caused by impairments in a basal ganglia thalamo-cortical circuit involved in syllable selection and initiation. Brain Lang. 2013 Sep; 126(3):263-78.
    View in: PubMed
  3. Niziolek CA, Guenther FH. Vowel category boundaries enhance cortical and behavioral responses to speech feedback alterations. J Neurosci. 2013 Jul 17; 33(29):12090-8.
    View in: PubMed
  4. Brumberg JS, Lorenz SD, Galbraith BV, Guenther FH. The unlock project: A Python-based framework for practical brain-computer interface communication "app" development. Conf Proc IEEE Eng Med Biol Soc. 2012 Aug; 2012:2505-8.
    View in: PubMed
  5. Cai S, Beal DS, Ghosh SS, Tiede MK, Guenther FH, Perkell JS. Weak responses to auditory feedback perturbation during articulation in persons who stutter: evidence for abnormal auditory-motor transformation. PLoS One. 2012; 7(7):e41830.
    View in: PubMed
  6. Cai S, Ghosh SS, Guenther FH, Perkell JS. Focal manipulations of formant trajectories reveal a role of auditory feedback in the online control of both within-syllable and between-syllable speech timing. J Neurosci. 2011 Nov 9; 31(45):16483-90.
    View in: PubMed
  7. Brumberg JS, Wright EJ, Andreasen DS, Guenther FH, Kennedy PR. Classification of intended phoneme production from chronic intracortical microelectrode recordings in speech-motor cortex. Front Neurosci. 2011; 5:65.
    View in: PubMed
  8. Guenther FH, Brumberg JS. Brain-machine interfaces for real-time speech synthesis. Conf Proc IEEE Eng Med Biol Soc. 2011; 2011:5360-3.
    View in: PubMed
  9. Golfinopoulos E, Tourville JA, Bohland JW, Ghosh SS, Nieto-Castanon A, Guenther FH. fMRI investigation of unexpected somatosensory feedback perturbation during speech. Neuroimage. 2011 Apr 1; 55(3):1324-38.
    View in: PubMed
  10. Patel R, Niziolek C, Reilly K, Guenther FH. Prosodic adaptations to pitch perturbation in running speech. J Speech Lang Hear Res. 2011 Aug; 54(4):1051-9.
    View in: PubMed
  11. Ghosh SS, Matthies ML, Maas E, Hanson A, Tiede M, Ménard L, Guenther FH, Lane H, Perkell JS. An investigation of the relation between sibilant production and somatosensory and auditory acuity. J Acoust Soc Am. 2010 Nov; 128(5):3079-87.
    View in: PubMed
  12. Cai S, Ghosh SS, Guenther FH, Perkell JS. Adaptive auditory feedback control of the production of formant trajectories in the Mandarin triphthong /iau/ and its pattern of generalization. J Acoust Soc Am. 2010 Oct; 128(4):2033-48.
    View in: PubMed
  13. Brumberg JS, Guenther FH. Development of speech prostheses: current status and recent advances. Expert Rev Med Devices. 2010 Sep; 7(5):667-79.
    View in: PubMed
  14. Bohland JW, Bullock D, Guenther FH. Neural representations and mechanisms for the performance of simple speech sequences. J Cogn Neurosci. 2010 Jul; 22(7):1504-29.
    View in: PubMed
  15. Civier O, Tasko SM, Guenther FH. Overreliance on auditory feedback may lead to sound/syllable repetitions: simulations of stuttering and fluency-inducing conditions with a neural model of speech production. J Fluency Disord. 2010 Sep; 35(3):246-79.
    View in: PubMed
  16. Peeva MG, Guenther FH, Tourville JA, Nieto-Castanon A, Anton JL, Nazarian B, Alario FX. Distinct representations of phonemes, syllables, and supra-syllabic sequences in the speech production network. Neuroimage. 2010 Apr 1; 50(2):626-38.
    View in: PubMed
  17. Guenther FH, Brumberg JS, Wright EJ, Nieto-Castanon A, Tourville JA, Panko M, Law R, Siebert SA, Bartels JL, Andreasen DS, Ehirim P, Mao H, Kennedy PR. A wireless brain-machine interface for real-time speech synthesis. PLoS One. 2009; 4(12):e8218.
    View in: PubMed
  18. Terband H, Maassen B, Guenther FH, Brumberg J. Computational neural modeling of speech motor control in childhood apraxia of speech (CAS). J Speech Lang Hear Res. 2009 Dec; 52(6):1595-609.
    View in: PubMed
  19. Golfinopoulos E, Tourville JA, Guenther FH. The integration of large-scale neural network modeling and functional brain imaging in speech motor control. Neuroimage. 2010 Sep; 52(3):862-74.
    View in: PubMed
  20. Wright DL, Robin DA, Rhee J, Vaculin A, Jacks A, Guenther FH, Fox PT. Using the self-select paradigm to delineate the nature of speech motor programming. J Speech Lang Hear Res. 2009 Jun; 52(3):755-65.
    View in: PubMed
  21. Matthies ML, Guenther FH, Denny M, Perkell JS, Burton E, Vick J, Lane H, Tiede M, Zandipour M. Perception and production of /r/ allophones improve with hearing from a cochlear implant. J Acoust Soc Am. 2008 Nov; 124(5):3191-202.
    View in: PubMed
  22. Ghosh SS, Tourville JA, Guenther FH. A neuroimaging study of premotor lateralization and cerebellar involvement in the production of phonemes and syllables. J Speech Lang Hear Res. 2008 Oct; 51(5):1183-202.
    View in: PubMed
  23. Loui P, Guenther FH, Mathys C, Schlaug G. Action-perception mismatch in tone-deafness. Curr Biol. 2008 Apr 22; 18(8):R331-2.
    View in: PubMed
  24. Tourville JA, Reilly KJ, Guenther FH. Neural mechanisms underlying auditory feedback control of speech. Neuroimage. 2008 Feb 1; 39(3):1429-43.
    View in: PubMed
  25. Villacorta VM, Perkell JS, Guenther FH. Sensorimotor adaptation to feedback perturbations of vowel acoustics and its relation to perception. J Acoust Soc Am. 2007 Oct; 122(4):2306-19.
    View in: PubMed
  26. Lane H, Matthies ML, Guenther FH, Denny M, Perkell JS, Stockmann E, Tiede M, Vick J, Zandipour M. Effects of short- and long-term changes in auditory feedback on vowel and sibilant contrasts. J Speech Lang Hear Res. 2007 Aug; 50(4):913-27.
    View in: PubMed
  27. Lane H, Denny M, Guenther FH, Hanson HM, Marrone N, Matthies ML, Perkell JS, Stockmann E, Tiede M, Vick J, Zandipour M. On the structure of phoneme categories in listeners with cochlear implants. J Speech Lang Hear Res. 2007 Feb; 50(1):2-14.
    View in: PubMed
  28. Perkell JS, Denny M, Lane H, Guenther F, Matthies ML, Tiede M, Vick J, Zandipour M, Burton E. Effects of masking noise on vowel and sibilant contrasts in normal-hearing speakers and postlingually deafened cochlear implant users. J Acoust Soc Am. 2007 Jan; 121(1):505-18.
    View in: PubMed
  29. Guenther FH. Cortical interactions underlying the production of speech sounds. J Commun Disord. 2006 Sep-Oct; 39(5):350-65.
    View in: PubMed
  30. Bohland JW, Guenther FH. An fMRI investigation of syllable sequence production. Neuroimage. 2006 Aug 15; 32(2):821-41.
    View in: PubMed
  31. Lane H, Denny M, Guenther FH, Matthies ML, Menard L, Perkell JS, Stockmann E, Tiede M, Vic J, Zandipour M. Effects of bite blocks and hearing status on vowel production. J Acoust Soc Am. 2005 Sep; 118(3 Pt 1):1636-46.
    View in: PubMed
  32. Guenther FH, Ghosh SS, Tourville JA. Neural modeling and imaging of the cortical interactions underlying syllable production. Brain Lang. 2006 Mar; 96(3):280-301.
    View in: PubMed
  33. Nieto-Castanon A, Guenther FH, Perkell JS, Curtin HD. A modeling investigation of articulatory variability and acoustic stability during American English /r/ production. J Acoust Soc Am. 2005 May; 117(5):3196-212.
    View in: PubMed
  34. Perkell JS, Matthies ML, Tiede M, Lane H, Zandipour M, Marrone N, Stockmann E, Guenther FH. The distinctness of speakers' /s/-/S/ contrast is related to their auditory discrimination and use of an articulatory saturation effect. J Speech Lang Hear Res. 2004 Dec; 47(6):1259-69.
    View in: PubMed
  35. Perkell JS, Guenther FH, Lane H, Matthies ML, Stockmann E, Tiede M, Zandipour M. The distinctness of speakers' productions of vowel contrasts is related to their discrimination of the contrasts. J Acoust Soc Am. 2004 Oct; 116(4 Pt 1):2338-44.
    View in: PubMed
  36. Guenther FH, Nieto-Castanon A, Ghosh SS, Tourville JA. Representation of sound categories in auditory cortical maps. J Speech Lang Hear Res. 2004 Feb; 47(1):46-57.
    View in: PubMed
  37. Nieto-Castanon A, Ghosh SS, Tourville JA, Guenther FH. Region of interest based analysis of functional imaging data. Neuroimage. 2003 Aug; 19(4):1303-16.
    View in: PubMed
  38. Micci Barreca D, Guenther FH. A modeling study of potential sources of curvature in human reaching movements. J Mot Behav. 2001 Dec; 33(4):387-400.
    View in: PubMed
  39. Callan DE, Kent RD, Guenther FH, Vorperian HK. An auditory-feedback-based neural network model of speech production that is robust to developmental changes in the size and shape of the articulatory system. J Speech Lang Hear Res. 2000 Jun; 43(3):721-36.
    View in: PubMed
  40. Guenther FH. An analytical error invalidates the "depolarization" of the perceptual magnet effect. J Acoust Soc Am. 2000 Jun; 107(6):3576-80.
    View in: PubMed
  41. Guenther FH, Husain FT, Cohen MA, Shinn-Cunningham BG. Effects of categorization and discrimination training on auditory perceptual space. J Acoust Soc Am. 1999 Nov; 106(5):2900-12.
    View in: PubMed
  42. Guenther FH, Espy-Wilson CY, Boyce SE, Matthies ML, Zandipour M, Perkell JS. Articulatory tradeoffs reduce acoustic variability during American English /r/ production. J Acoust Soc Am. 1999 May; 105(5):2854-65.
    View in: PubMed
  43. Guenther FH, Hampson M, Johnson D. A theoretical investigation of reference frames for the planning of speech movements. Psychol Rev. 1998 Oct; 105(4):611-33.
    View in: PubMed
  44. Cameron S, Grossberg S, Guenther FH. A self-organizing neural network architecture for navigation using optic flow. Neural Comput. 1998 Feb 15; 10(2):313-52.
    View in: PubMed
  45. Guenther FH, Gjaja MN. The perceptual magnet effect as an emergent property of neural map formation. J Acoust Soc Am. 1996 Aug; 100(2 Pt 1):1111-21.
    View in: PubMed
  46. Guenther FH. Speech sound acquisition, coarticulation, and rate effects in a neural network model of speech production. Psychol Rev. 1995 Jul; 102(3):594-621.
    View in: PubMed
  47. Guenther FH. A neural network model of speech acquisition and motor equivalent speech production. Biol Cybern. 1994; 72(1):43-53.
    View in: PubMed
  48. Guenther FH, Bullock D, Greve D, Grossberg S. Neural Representations for Sensorimotor Control. III. Learning a Body-Centered Representation of a Three-Dimensional Target Position. J Cogn Neurosci. 1994; 6(4):341-58.
    View in: PubMed
  49. Greve D, Grossberg S, Guenther F, Bullock D. Neural representations for sensory-motor control, I: Head-centered 3-D target positions from opponent eye commands. Acta Psychol (Amst). 1993 Mar; 82(1-3):115-38.
    View in: PubMed
  50. Bullock D, Grossberg S, Guenther FH. A self-organizing neural model of motor equivalent reaching and tool use by a multijoint arm. J Cogn Neurosci. 1993; 5(4):408-35.
    View in: PubMed
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