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Sebastian Schneeweiss, S.D., M.D.

TitleProfessor of Medicine
InstitutionBrigham and Women's Hospital
DepartmentMedicine
AddressBrigham and Women's Hospital
General Medicine
1620 Tremont St
Boston MA 02120
Phone617/547-5275
Fax617/232-8602
Other Positions
TitleProfessor in the Department of Epidemiology
InstitutionHarvard School of Public Health
DepartmentEpidemiology


 Overview 
 overview
Sebastian Schneeweiss is a Professor of Medicine and Epidemiology at Harvard Medical School and Vice Chief of the Division of Pharmacoepidemiology and Pharmacoeconomics of the Dept. of Medicine, Brigham and Women’s Hospital.

He is Principal Investigator of the BWH DEcIDE Research Center on Comparative Effectiveness Research and the DEcIDE Methods Center both funded by AHRQ and Director of the Harvard-Brigham Drug Safety Research Center funded by FDA/CDER. His research is funded by multiple NIH grants and focuses on the comparative effectiveness and safety of biopharmaceuticals and analytic methods to improve the validity of epidemiologic studies using complex healthcare databases.

Dr. Schneeweiss is Past President of the International Society for Pharmacoepidemiology and is Fellow of the American College of Epidemiology, the American College of Clinical Pharmacology, and the International Society for Pharmacoepidemiology. He is voting consultant to the FDA Drug Safety and Risk Management Advisory Committee and member of the Methods Committee of the Patient Centered Outcomes Research Institute.

He received his medical training at the University of Munich Medical School and his doctoral degree in Pharmacoepidemiology from Harvard.


 Bibliographic 
 selected publications
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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  1. Franklin JM, Rassen JA, Bartels DB, Schneeweiss S. Prospective cohort studies of newly marketed medications: using covariate data to inform the design of large-scale studies. Epidemiology. 2014 Jan; 25(1):126-33.
    View in: PubMed
  2. Kim SC, Schmidt BM, Franklin JM, Liu J, Solomon DH, Schneeweiss S. Clinical and health care use characteristics of patients newly starting allopurinol, febuxostat, and colchicine for the treatment of gout. Arthritis Care Res (Hoboken). 2013 Dec; 65(12):2008-14.
    View in: PubMed
  3. Kim SC, Schneeweiss S, Liu J, Solomon DH. Risk of venous thromboembolism in patients with rheumatoid arthritis. Arthritis Care Res (Hoboken). 2013 Oct; 65(10):1600-7.
    View in: PubMed
  4. Bateman BT, Bykov K, Choudhry NK, Schneeweiss S, Gagne JJ, Polinski JM, Franklin JM, Doherty M, Fischer MA, Rassen JA. Type of stress ulcer prophylaxis and risk of nosocomial pneumonia in cardiac surgical patients: cohort study. BMJ. 2013; 347:f5416.
    View in: PubMed
  5. Kim SC, Gillet VG, Feldman S, Lii H, Toh S, Brown JS, Katz JN, Solomon DH, Schneeweiss S. Validation of claims-based algorithms for identification of high-grade cervical dysplasia and cervical cancer. Pharmacoepidemiol Drug Saf. 2013 Nov; 22(11):1239-44.
    View in: PubMed
  6. Gagne JJ, Bykov K, Willke RJ, Kahler KH, Subedi P, Schneeweiss S. Treatment dynamics of newly marketed drugs and implications for comparative effectiveness research. Value Health. 2013 Sep-Oct; 16(6):1054-62.
    View in: PubMed
  7. Patrick AR, Franklin JM, Weinstein MC, Glynn RJ, Schneeweiss S. Sequential Value-of-Information Assessment for Prospective Drug Safety Monitoring Using Claims Databases: The Comparative Safety of Prasugrel v. Clopidogrel. Med Decis Making. 2013 Oct; 33(7):949-60.
    View in: PubMed
  8. Schneeweiss S, Seeger JD, Jackson JW, Smith SR. Methods for comparative effectiveness research/patient-centered outcomes research: from efficacy to effectiveness. J Clin Epidemiol. 2013 Aug; 66(8 Suppl):S1-4.
    View in: PubMed
  9. Patorno E, Glynn RJ, Hernandez-Diaz S, Avorn J, Wahl PM, Bohn RL, Mines D, Liu J, Schneeweiss S. Risk of ischemic cerebrovascular and coronary events in adult users of anticonvulsant medications in routine care settings. J Am Heart Assoc. 2013; 2(4):e000208.
    View in: PubMed
  10. Huber CA, Schneeweiss S, Signorell A, Reich O. Improved prediction of medical expenditures and health care utilization using an updated chronic disease score and claims data. J Clin Epidemiol. 2013 Oct; 66(10):1118-27.
    View in: PubMed
  11. Polinski JM, Shrank WH, Glynn RJ, Schneeweiss S, Huskamp HA, Roebuck MC. Response letter to eltonsy and colleagues. J Am Geriatr Soc. 2013 May; 61(5):848-9.
    View in: PubMed
  12. Wang SV, Gagne JJ, Glynn RJ, Schneeweiss S. Case-crossover Studies of Therapeutics: Design Approaches to Addressing Time-varying Prognosis in Elderly Populations. Epidemiology. 2013 May; 24(3):375-8.
    View in: PubMed
  13. Rassen JA, Shelat AA, Franklin JM, Glynn RJ, Solomon DH, Schneeweiss S. Matching by propensity score in cohort studies with three treatment groups. Epidemiology. 2013 May; 24(3):401-9.
    View in: PubMed
  14. Bateman BT, Rassen JA, Schneeweiss S, Bykov K, Franklin JM, Gagne JJ, Polinski JM, Liu J, Kulik A, Fischer MA, Choudhry NK. Adjuvant vancomycin for antibiotic prophylaxis and risk of Clostridium difficile infection after coronary artery bypass graft surgery. J Thorac Cardiovasc Surg. 2013 Aug; 146(2):472-8.
    View in: PubMed
  15. Gagne JJ, Schneeweiss S. Comment on 'Empirical assessment of methods for risk identification in healthcare data: results from the experiments of the Observational Medical Outcomes Partnership'. Stat Med. 2013 Mar 15; 32(6):1073-4.
    View in: PubMed
  16. Schneeweiss S, Rassen JA, Glynn RJ, Myers J, Daniel GW, Singer J, Solomon DH, Kim S, Rothman KJ, Liu J, Avorn J. Supplementing claims data with outpatient laboratory test results to improve confounding adjustment in effectiveness studies of lipid-lowering treatments. BMC Med Res Methodol. 2012; 12:180.
    View in: PubMed
  17. Liu W, Brookhart MA, Schneeweiss S, Mi X, Setoguchi S. Implications of m bias in epidemiologic studies: a simulation study. Am J Epidemiol. 2012 Nov 15; 176(10):938-48.
    View in: PubMed
  18. Choudhry NK, Fischer MA, Avorn JL, Lee JL, Schneeweiss S, Solomon DH, Berman C, Jan S, Lii J, Mahoney JJ, Shrank WH. The impact of reducing cardiovascular medication copayments on health spending and resource utilization. J Am Coll Cardiol. 2012 Oct 30; 60(18):1817-24.
    View in: PubMed
  19. Kim SC, Schneeweiss S, Myers JA, Liu J, Solomon DH. No differences in cancer screening rates in patients with rheumatoid arthritis compared to the general population. Arthritis Rheum. 2012 Oct; 64(10):3076-82.
    View in: PubMed
  20. Selby JV, Fleurence R, Lauer M, Schneeweiss S. Reviewing hypothetical migraine studies using funding criteria from the Patient-Centered Outcomes Research Institute. Health Aff (Millwood). 2012 Oct; 31(10):2193-9.
    View in: PubMed
  21. Johnson ES, Bartman BA, Briesacher BA, Fleming NS, Gerhard T, Kornegay CJ, Nourjah P, Sauer B, Schumock GT, Sedrakyan A, Stürmer T, West SL, Schneeweiss S. The incident user design in comparative effectiveness research. Pharmacoepidemiol Drug Saf. 2013 Jan; 22(1):1-6.
    View in: PubMed
  22. Huybrechts KF, Seeger JD, Rothman KJ, Glynn RJ, Avorn J, Schneeweiss S. Bias in comparative effectiveness studies due to regional variation in medical practice intensity: a legitimate concern, or much ado about nothing? Circ Cardiovasc Qual Outcomes. 2012 Sep 1; 5(5):e61-4.
    View in: PubMed
  23. Polinski JM, Shrank WH, Glynn RJ, Huskamp HA, Christopher Roebuck M, Schneeweiss S. Association between the Part D coverage gap and adverse health outcomes. J Am Geriatr Soc. 2012 Aug; 60(8):1408-17.
    View in: PubMed
  24. Schneeweiss S, Gagne JJ, Patrick AR, Choudhry NK, Avorn J. Comparative efficacy and safety of new oral anticoagulants in patients with atrial fibrillation. Circ Cardiovasc Qual Outcomes. 2012 Jul 1; 5(4):480-6.
    View in: PubMed
  25. Kulik A, Rassen JA, Myers J, Schneeweiss S, Gagne J, Polinski JM, Liu J, Fischer MA, Choudhry NK. Comparative effectiveness of preventative therapy for venous thromboembolism after coronary artery bypass graft surgery. Circ Cardiovasc Interv. 2012 Aug 1; 5(4):590-6.
    View in: PubMed
  26. Solomon DH, Mercer E, Woo SB, Avorn J, Schneeweiss S, Treister N. Defining the epidemiology of bisphosphonate-associated osteonecrosis of the jaw: prior work and current challenges. Osteoporos Int. 2013 Jan; 24(1):237-44.
    View in: PubMed
  27. Juillerat P, Schneeweiss S, Cook EF, Ananthakrishnan AN, Mogun H, Korzenik JR. Drugs that inhibit gastric acid secretion may alter the course of inflammatory bowel disease. Aliment Pharmacol Ther. 2012 Aug; 36(3):239-47.
    View in: PubMed
  28. Gagne JJ, Glynn RJ, Rassen JA, Walker AM, Daniel GW, Sridhar G, Schneeweiss S. Active safety monitoring of newly marketed medications in a distributed data network: application of a semi-automated monitoring system. Clin Pharmacol Ther. 2012 Jul; 92(1):80-6.
    View in: PubMed
  29. Wahl PM, Gagne JJ, Wasser TE, Eisenberg DF, Rodgers JK, Daniel GW, Wilson M, Schneeweiss S, Rassen JA, Patrick AR, Avorn J, Bohn RL. Early steps in the development of a claims-based targeted healthcare safety monitoring system and application to three empirical examples. Drug Saf. 2012 May 1; 35(5):407-16.
    View in: PubMed
  30. Schneeweiss S, Seeger JD, Smith SR. Methods for developing and analyzing clinically rich data for patient-centered outcomes research: an overview. Pharmacoepidemiol Drug Saf. 2012 May; 21 Suppl 2:1-5.
    View in: PubMed
  31. Polinski JM, Schneeweiss S, Glynn RJ, Lii J, Rassen JA. Confronting "confounding by health system use" in Medicare Part D: comparative effectiveness of propensity score approaches to confounding adjustment. Pharmacoepidemiol Drug Saf. 2012 May; 21 Suppl 2:90-8.
    View in: PubMed
  32. Rassen JA, Shelat AA, Myers J, Glynn RJ, Rothman KJ, Schneeweiss S. One-to-many propensity score matching in cohort studies. Pharmacoepidemiol Drug Saf. 2012 May; 21 Suppl 2:69-80.
    View in: PubMed
  33. Glynn RJ, Gagne JJ, Schneeweiss S. Role of disease risk scores in comparative effectiveness research with emerging therapies. Pharmacoepidemiol Drug Saf. 2012 May; 21 Suppl 2:138-47.
    View in: PubMed
  34. Polinski JM, Shrank WH, Glynn RJ, Huskamp HA, Roebuck MC, Schneeweiss S. Beneficiaries with cardiovascular disease and thePart D coverage gap. Circ Cardiovasc Qual Outcomes. 2012 May; 5(3):387-95.
    View in: PubMed
  35. Kim SY, Schneeweiss S, Liu J, Solomon DH. Effects of disease-modifying antirheumatic drugs on nonvertebral fracture risk in rheumatoid arthritis: a population-based cohort study. J Bone Miner Res. 2012 Apr; 27(4):789-96.
    View in: PubMed
  36. Desai NR, Shrank WH, Fischer MA, Avorn J, Liberman JN, Schneeweiss S, Pakes J, Brennan TA, Choudhry NK. Patterns of medication initiation in newly diagnosed diabetes mellitus: quality and cost implications. Am J Med. 2012 Mar; 125(3):302.e1-7.
    View in: PubMed
  37. Rassen JA, Schneeweiss S. Newly marketed medications present unique challenges for nonrandomized comparative effectiveness analyses. J Comp Eff Res. 2012 Mar; 1(2):109-11.
    View in: PubMed
  38. Gagne JJ, Rassen JA, Walker AM, Glynn RJ, Schneeweiss S. Active safety monitoring of new medical products using electronic healthcare data: selecting alerting rules. Epidemiology. 2012 Mar; 23(2):238-46.
    View in: PubMed
  39. Huybrechts KF, Gerhard T, Crystal S, Olfson M, Avorn J, Levin R, Lucas JA, Schneeweiss S. Differential risk of death in older residents in nursing homes prescribed specific antipsychotic drugs: population based cohort study. BMJ. 2012; 344:e977.
    View in: PubMed
  40. Huybrechts KF, Schneeweiss S, Gerhard T, Olfson M, Avorn J, Levin R, Lucas JA, Crystal S. Comparative safety of antipsychotic medications in nursing home residents. J Am Geriatr Soc. 2012 Mar; 60(3):420-9.
    View in: PubMed
  41. Huybrechts KF, Rothman KJ, Brookhart MA, Silliman RA, Crystal S, Gerhard T, Schneeweiss S. Variation in antipsychotic treatment choice across US nursing homes. J Clin Psychopharmacol. 2012 Feb; 32(1):11-7.
    View in: PubMed
  42. Polinski JM, Brookhart MA, Glynn RJ, Schneeweiss S. Medicare part D's impact on antipsychotic drug use and costs among elderly patients without prior drug insurance. J Clin Psychopharmacol. 2012 Feb; 32(1):3-10.
    View in: PubMed
  43. Rassen JA, Glynn RJ, Rothman KJ, Setoguchi S, Schneeweiss S. Response to commentary by Marcus and Gibbons. Pharmacoepidemiol Drug Saf. 2012 Jan 30.
    View in: PubMed
  44. Gagne JJ, Avorn J, Shrank WH, Schneeweiss S. Comment: generic substitution of antiepileptic drugs: a systematic review of prospective and retrospective studies. Ann Pharmacother. 2012 Feb; 46(2):303-4; author reply 304.
    View in: PubMed
  45. Gagne JJ, Walker AM, Glynn RJ, Rassen JA, Schneeweiss S. An event-based approach for comparing the performance of methods for prospective medical product monitoring. Pharmacoepidemiol Drug Saf. 2012 Jun; 21(6):631-9.
    View in: PubMed
  46. Platt R, Carnahan RM, Brown JS, Chrischilles E, Curtis LH, Hennessy S, Nelson JC, Racoosin JA, Robb M, Schneeweiss S, Toh S, Weiner MG. The U.S. Food and Drug Administration's Mini-Sentinel program: status and direction. Pharmacoepidemiol Drug Saf. 2012 Jan; 21 Suppl 1:1-8.
    View in: PubMed
  47. Rassen JA, Schneeweiss S. Using high-dimensional propensity scores to automate confounding control in a distributed medical product safety surveillance system. Pharmacoepidemiol Drug Saf. 2012 Jan; 21 Suppl 1:41-9.
    View in: PubMed
  48. Gagne JJ, Fireman B, Ryan PB, Maclure M, Gerhard T, Toh S, Rassen JA, Nelson JC, Schneeweiss S. Design considerations in an active medical product safety monitoring system. Pharmacoepidemiol Drug Saf. 2012 Jan; 21 Suppl 1:32-40.
    View in: PubMed
  49. Rassen JA, Glynn RJ, Rothman KJ, Setoguchi S, Schneeweiss S. Applying propensity scores estimated in a full cohort to adjust for confounding in subgroup analyses. Pharmacoepidemiol Drug Saf. 2011 Dec 8.
    View in: PubMed
  50. Choudhry NK, Avorn J, Glynn RJ, Antman EM, Schneeweiss S, Toscano M, Reisman L, Fernandes J, Spettell C, Lee JL, Levin R, Brennan T, Shrank WH. Full coverage for preventive medications after myocardial infarction. N Engl J Med. 2011 Dec 1; 365(22):2088-97.
    View in: PubMed
  51. Schneeweiss S, Gagne JJ, Glynn RJ, Ruhl M, Rassen JA. Assessing the comparative effectiveness of newly marketed medications: methodological challenges and implications for drug development. Clin Pharmacol Ther. 2011 Dec; 90(6):777-90.
    View in: PubMed
  52. Fischer MA, Choudhry NK, Brill G, Avorn J, Schneeweiss S, Hutchins D, Liberman JN, Brennan TA, Shrank WH. Trouble getting started: predictors of primary medication nonadherence. Am J Med. 2011 Nov; 124(11):1081.e9-22.
    View in: PubMed
  53. Myers JA, Rassen JA, Gagne JJ, Huybrechts KF, Schneeweiss S, Rothman KJ, Joffe MM, Glynn RJ. Effects of adjusting for instrumental variables on bias and precision of effect estimates. Am J Epidemiol. 2011 Dec 1; 174(11):1213-22.
    View in: PubMed
  54. Gomes T, Juurlink DN, Ho JM, Schneeweiss S, Mamdani MM. Risk of serious falls associated with oxybutynin and tolterodine: a population based study. J Urol. 2011 Oct; 186(4):1340-4.
    View in: PubMed
  55. Schneeweiss S, Rassen J. Re: Confounding adjustment via a semi-automated high-dimensional propensity score algorithm: an application to electronic medical records. Pharmacoepidemiol Drug Saf. 2011 Oct; 20(10):1110-1; author reply 1112.
    View in: PubMed
  56. Huybrechts KF, Brookhart MA, Rothman KJ, Silliman RA, Gerhard T, Crystal S, Schneeweiss S. Comparison of different approaches to confounding adjustment in a study on the association of antipsychotic medication with mortality in older nursing home patients. Am J Epidemiol. 2011 Nov 1; 174(9):1089-99.
    View in: PubMed
  57. Polinski JM, Shrank WH, Huskamp HA, Glynn RJ, Liberman JN, Schneeweiss S. Changes in drug utilization during a gap in insurance coverage: an examination of the medicare Part D coverage gap. PLoS Med. 2011 Aug; 8(8):e1001075.
    View in: PubMed
  58. Solomon DH, Massarotti E, Garg R, Liu J, Canning C, Schneeweiss S. Association between disease-modifying antirheumatic drugs and diabetes risk in patients with rheumatoid arthritis and psoriasis. JAMA. 2011 Jun 22; 305(24):2525-31.
    View in: PubMed
  59. Rassen JA, Solomon DH, Glynn RJ, Schneeweiss S. Simultaneously assessing intended and unintended treatment effects of multiple treatment options: a pragmatic "matrix design". Pharmacoepidemiol Drug Saf. 2011 Jul; 20(7):675-83.
    View in: PubMed
  60. Rassen JA, Glynn RJ, Brookhart MA, Schneeweiss S. Covariate selection in high-dimensional propensity score analyses of treatment effects in small samples. Am J Epidemiol. 2011 Jun 15; 173(12):1404-13.
    View in: PubMed
  61. Kim SY, Solomon DH, Liu J, Chang CL, Daniel GW, Schneeweiss S. Accuracy of identifying neutropenia diagnoses in outpatient claims data. Pharmacoepidemiol Drug Saf. 2011 Jul; 20(7):709-13.
    View in: PubMed
  62. Choudhry NK, Fischer MA, Avorn J, Liberman JN, Schneeweiss S, Pakes J, Brennan TA, Shrank WH. The implications of therapeutic complexity on adherence to cardiovascular medications. Arch Intern Med. 2011 May 9; 171(9):814-22.
    View in: PubMed
  63. Goldberg NH, Schneeweiss S, Kowal MK, Gagne JJ. Availability of comparative efficacy data at the time of drug approval in the United States. JAMA. 2011 May 4; 305(17):1786-9.
    View in: PubMed
  64. Kim SY, Schneeweiss S, Katz JN, Levin R, Solomon DH. Oral bisphosphonates and risk of subtrochanteric or diaphyseal femur fractures in a population-based cohort. J Bone Miner Res. 2011 May; 26(5):993-1001.
    View in: PubMed
  65. Margulis AV, Choudhry NK, Dormuth CR, Schneeweiss S. Variation in initiating secondary prevention after myocardial infarction by hospitals and physicians, 1997 through 2004. Pharmacoepidemiol Drug Saf. 2011 Oct; 20(10):1088-97.
    View in: PubMed
  66. Huybrechts KF, Rothman KJ, Silliman RA, Brookhart MA, Schneeweiss S. Risk of death and hospital admission for major medical events after initiation of psychotropic medications in older adults admitted to nursing homes. CMAJ. 2011 Apr 19; 183(7):E411-9.
    View in: PubMed
  67. Patrick AR, Schneeweiss S, Brookhart MA, Glynn RJ, Rothman KJ, Avorn J, Stürmer T. The implications of propensity score variable selection strategies in pharmacoepidemiology: an empirical illustration. Pharmacoepidemiol Drug Saf. 2011 Jun; 20(6):551-9.
    View in: PubMed
  68. Brookhart MA, Bradbury BD, Avorn J, Schneeweiss S, Winkelmayer WC. The effect of altitude change on anemia treatment response in hemodialysis patients. Am J Epidemiol. 2011 Apr 1; 173(7):768-77.
    View in: PubMed
  69. Schneeweiss S, Avorn J. Postmarketing studies of drug safety. BMJ. 2011; 342:d342.
    View in: PubMed
  70. Polinski JM, Schneeweiss S, Maclure M, Marshall B, Ramsden S, Dormuth C. Time series evaluation of an intervention to increase statin tablet splitting by general practitioners. Clin Ther. 2011 Feb; 33(2):235-43.
    View in: PubMed
  71. Choudhry NK, Fischer MA, Avorn J, Liberman JN, Schneeweiss S, Pakes J, Brennan TA, Shrank WH. The Implications of Therapeutic Complexity on Adherence to Cardiovascular Medications. Arch Intern Med. 2011 Jan 10.
    View in: PubMed
  72. Gagne JJ, Glynn RJ, Avorn J, Levin R, Schneeweiss S. A combined comorbidity score predicted mortality in elderly patients better than existing scores. J Clin Epidemiol. 2011 Jul; 64(7):749-59.
    View in: PubMed
  73. Solomon DH, Rassen JA, Glynn RJ, Garneau K, Levin R, Lee J, Schneeweiss S. The comparative safety of opioids for nonmalignant pain in older adults. Arch Intern Med. 2010 Dec 13; 170(22):1979-86.
    View in: PubMed
  74. Solomon DH, Rassen JA, Glynn RJ, Lee J, Levin R, Schneeweiss S. The comparative safety of analgesics in older adults with arthritis. Arch Intern Med. 2010 Dec 13; 170(22):1968-76.
    View in: PubMed
  75. Kim SY, Schneeweiss S, Katz JN, Levin R, Solomon DH. Oral bisphosphonates and risk of subtrochanteric or diaphyseal femur fractures in a population-based cohort. J Bone Miner Res. 2010 Nov 18.
    View in: PubMed
  76. Shrank WH, Choudhry NK, Fischer MA, Avorn J, Powell M, Schneeweiss S, Liberman JN, Dollear T, Brennan TA, Brookhart MA. The epidemiology of prescriptions abandoned at the pharmacy. Ann Intern Med. 2010 Nov 16; 153(10):633-40.
    View in: PubMed
  77. Choudhry NK, Fischer MA, Avorn J, Schneeweiss S, Solomon DH, Berman C, Jan S, Liu J, Lii J, Brookhart MA, Mahoney JJ, Shrank WH. At Pitney Bowes, value-based insurance design cut copayments and increased drug adherence. Health Aff (Millwood). 2010 Nov; 29(11):1995-2001.
    View in: PubMed
  78. Patrick AR, Miller M, Barber CW, Wang PS, Canning CF, Schneeweiss S. Identification of hospitalizations for intentional self-harm when E-codes are incompletely recorded. Pharmacoepidemiol Drug Saf. 2010 Dec; 19(12):1263-75.
    View in: PubMed
  79. Polinski JM, Kilabuk E, Schneeweiss S, Brennan T, Shrank WH. Changes in drug use and out-of-pocket costs associated with Medicare Part D implementation: a systematic review. J Am Geriatr Soc. 2010 Sep; 58(9):1764-79.
    View in: PubMed
  80. Kim SY, Schneeweiss S, Liu J, Daniel GW, Chang CL, Garneau K, Solomon DH. Risk of osteoporotic fracture in a large population-based cohort of patients with rheumatoid arthritis. Arthritis Res Ther. 2010; 12(4):R154.
    View in: PubMed
  81. Rassen JA, Avorn J, Schneeweiss S. Multivariate-adjusted pharmacoepidemiologic analyses of confidential information pooled from multiple health care utilization databases. Pharmacoepidemiol Drug Saf. 2010 Aug; 19(8):848-57.
    View in: PubMed
  82. Schneeweiss S. A basic study design for expedited safety signal evaluation based on electronic healthcare data. Pharmacoepidemiol Drug Saf. 2010 Aug; 19(8):858-68.
    View in: PubMed
  83. Gagne JJ, Avorn J, Shrank WH, Schneeweiss S. Refilling and switching of antiepileptic drugs and seizure-related events. Clin Pharmacol Ther. 2010 Sep; 88(3):347-53.
    View in: PubMed
  84. Solomon DH, Love TJ, Canning C, Schneeweiss S. Risk of diabetes among patients with rheumatoid arthritis, psoriatic arthritis and psoriasis. Ann Rheum Dis. 2010 Dec; 69(12):2114-7.
    View in: PubMed
  85. Wahl PM, Rodgers K, Schneeweiss S, Gage BF, Butler J, Wilmer C, Nash M, Esper G, Gitlin N, Osborn N, Short LJ, Bohn RL. Validation of claims-based diagnostic and procedure codes for cardiovascular and gastrointestinal serious adverse events in a commercially-insured population. Pharmacoepidemiol Drug Saf. 2010 Jun; 19(6):596-603.
    View in: PubMed
  86. Rassen JA, Solomon DH, Curtis JR, Herrinton L, Schneeweiss S. Privacy-maintaining propensity score-based pooling of multiple databases applied to a study of biologics. Med Care. 2010 Jun; 48(6 Suppl):S83-9.
    View in: PubMed
  87. Brookhart MA, Stürmer T, Glynn RJ, Rassen J, Schneeweiss S. Confounding control in healthcare database research: challenges and potential approaches. Med Care. 2010 Jun; 48(6 Suppl):S114-20.
    View in: PubMed
  88. Brookhart MA, Rassen JA, Schneeweiss S. Instrumental variable methods in comparative safety and effectiveness research. Pharmacoepidemiol Drug Saf. 2010 Jun; 19(6):537-54.
    View in: PubMed
  89. Dreyer NA, Schneeweiss S, McNeil BJ, Berger ML, Walker AM, Ollendorf DA, Gliklich RE. GRACE principles: recognizing high-quality observational studies of comparative effectiveness. Am J Manag Care. 2010 Jun; 16(6):467-71.
    View in: PubMed
  90. Schneeweiss S, Patrick AR, Solomon DH, Mehta J, Dormuth C, Miller M, Lee JC, Wang PS. Variation in the risk of suicide attempts and completed suicides by antidepressant agent in adults: a propensity score-adjusted analysis of 9 years' data. Arch Gen Psychiatry. 2010 May; 67(5):497-506.
    View in: PubMed
  91. Patorno E, Bohn RL, Wahl PM, Avorn J, Patrick AR, Liu J, Schneeweiss S. Anticonvulsant medications and the risk of suicide, attempted suicide, or violent death. JAMA. 2010 Apr 14; 303(14):1401-9.
    View in: PubMed
  92. Schneeweiss S, Patrick AR, Solomon DH, Dormuth CR, Miller M, Mehta J, Lee JC, Wang PS. Comparative safety of antidepressant agents for children and adolescents regarding suicidal acts. Pediatrics. 2010 May; 125(5):876-88.
    View in: PubMed
  93. Polinski JM, Bhandari A, Saya UY, Schneeweiss S, Shrank WH. Medicare beneficiaries' knowledge of and choices regarding Part D, 2005 to the present. J Am Geriatr Soc. 2010 May; 58(5):950-66.
    View in: PubMed
  94. Brookhart MA, Schneeweiss S, Avorn J, Bradbury BD, Liu J, Winkelmayer WC. Comparative mortality risk of anemia management practices in incident hemodialysis patients. JAMA. 2010 Mar 3; 303(9):857-64.
    View in: PubMed
  95. Wang PS, Patrick AR, Dormuth C, Maclure M, Avorn J, Canning CF, Schneeweiss S. Impact of drug cost sharing on service use and adverse clinical outcomes in elderly receiving antidepressants. J Ment Health Policy Econ. 2010 Mar; 13(1):37-44.
    View in: PubMed
  96. Gagne JJ, Patrick AR, Wang PS, Schneeweiss S. Health advisories and patterns of patient monitoring among new users of antidepressant medications. J Clin Psychopharmacol. 2009 Dec; 29(6):590-4.
    View in: PubMed
  97. Francis ML, Scaife SL, Zahnd WE, Cook EF, Schneeweiss S. Joint replacement surgeries among medicare beneficiaries in rural compared with urban areas. Arthritis Rheum. 2009 Dec; 60(12):3554-62.
    View in: PubMed
  98. Schneeweiss S, Glynn RJ, Avorn J, Mamdani M, Mogun H, Solomon DH. NSAID switching and short-term gastrointestinal outcome rates after the withdrawal of rofecoxib. Pharmacoepidemiol Drug Saf. 2009 Dec; 18(12):1134-42.
    View in: PubMed
  99. Rassen JA, Mittleman MA, Glynn RJ, Alan Brookhart M, Schneeweiss S. Safety and effectiveness of bivalirudin in routine care of patients undergoing percutaneous coronary intervention. Eur Heart J. 2010 Mar; 31(5):561-72.
    View in: PubMed
  100. Rassen JA, Choudhry NK, Avorn J, Schneeweiss S. Cardiovascular outcomes and mortality in patients using clopidogrel with proton pump inhibitors after percutaneous coronary intervention or acute coronary syndrome. Circulation. 2009 Dec 8; 120(23):2322-9.
    View in: PubMed
  101. Schneeweiss S. On guidelines for comparative effectiveness research using nonrandomized studies in secondary data sources. Value Health. 2009 Nov-Dec; 12(8):1041.
    View in: PubMed
  102. Polinski JM, Schneeweiss S, Levin R, Shrank WH. Completeness of retail pharmacy claims data: implications for pharmacoepidemiologic studies and pharmacy practice in elderly patients. Clin Ther. 2009 Sep; 31(9):2048-59.
    View in: PubMed
  103. Shrank WH, Patrick A, Gleason PP, Canning C, Walters C, Heaton AH, Jan S, Brookhart MA, Schneeweiss S, Solomon DH, Wolf MS, Avorn J, Choudhry NK. An evaluation of the relationship between the implementation of a newly designed prescription drug label at Target pharmacies and health outcomes. Med Care. 2009 Sep; 47(9):1031-5.
    View in: PubMed
  104. Avorn J, Schneeweiss S. Managing drug-risk information--what to do with all those new numbers. N Engl J Med. 2009 Aug 13; 361(7):647-9.
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  105. Avorn J, Schneeweiss S. Imuunosuppressants, mortality, and risk of cancer. BMJ. 2009; 339:b1645.
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  106. Schneeweiss S, Rassen JA, Glynn RJ, Avorn J, Mogun H, Brookhart MA. High-dimensional propensity score adjustment in studies of treatment effects using health care claims data. Epidemiology. 2009 Jul; 20(4):512-22.
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  107. Dormuth CR, Maclure M, Carney G, Schneeweiss S, Bassett K, Wright JM. Rosiglitazone and myocardial infarction in patients previously prescribed metformin. PLoS One. 2009; 4(6):e6080.
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  108. Schneeweiss S, Korzenik J, Solomon DH, Canning C, Lee J, Bressler B. Infliximab and other immunomodulating drugs in patients with inflammatory bowel disease and the risk of serious bacterial infections. Aliment Pharmacol Ther. 2009 Aug; 30(3):253-64.
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  109. Dormuth CR, Neumann P, Maclure M, Glynn RJ, Schneeweiss S. Effects of prescription coinsurance and income-based deductibles on net health plan spending for older users of inhaled medications. Med Care. 2009 May; 47(5):508-16.
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  110. Rassen JA, Brookhart MA, Glynn RJ, Mittleman MA, Schneeweiss S. Instrumental variables I: instrumental variables exploit natural variation in nonexperimental data to estimate causal relationships. J Clin Epidemiol. 2009 Dec; 62(12):1226-32.
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  111. Rassen JA, Brookhart MA, Glynn RJ, Mittleman MA, Schneeweiss S. Instrumental variables II: instrumental variable application-in 25 variations, the physician prescribing preference generally was strong and reduced covariate imbalance. J Clin Epidemiol. 2009 Dec; 62(12):1233-41.
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  112. Gagne JJ, Griesdale DE, Schneeweiss S. Aprotinin and the risk of death and renal dysfunction in patients undergoing cardiac surgery: a meta-analysis of epidemiologic studies. Pharmacoepidemiol Drug Saf. 2009 Apr; 18(4):259-68.
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  113. Setoguchi S, Nohria A, Rassen JA, Stevenson LW, Schneeweiss S. Maximum potential benefit of implantable defibrillators in preventing sudden death after hospital admission because of heart failure. CMAJ. 2009 Mar 17; 180(6):611-6.
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  114. Schneeweiss S, Doherty M, Zhu S, Funch D, Schlienger RG, Fernandez-Vidaurre C, Seeger JD. Topical treatments with pimecrolimus, tacrolimus and medium- to high-potency corticosteroids, and risk of lymphoma. Dermatology. 2009; 219(1):7-21.
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  115. Shrank WH, Gleason PP, Canning C, Walters C, Heaton AH, Jan S, Patrick A, Brookhart MA, Schneeweiss S, Solomon DH, Avorn J, Choudhry NK. Can improved prescription medication labeling influence adherence to chronic medications? An evaluation of the Target pharmacy label. J Gen Intern Med. 2009 May; 24(5):570-8.
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  116. Shrank WH, Choudhry NK, Solomon DH, Snedden TM, Lee TH, Glynn RJ, Brown TV, Jolda C, Spetman M, Brookhart MA, Schneeweiss S, Avorn J. Rationale and design of the Study Assessing the Effect of Cardiovascular Medications Provided as Low-cost, Evidence-based Generic Samples (SAMPLES) trial. Am Heart J. 2009 Apr; 157(4):613-9.
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  117. Schneeweiss S, Patrick AR, Pedan A, Varasteh L, Levin R, Liu N, Shrank WH. The effect of Medicare Part D coverage on drug use and cost sharing among seniors without prior drug benefits. Health Aff (Millwood). 2009 Mar-Apr; 28(2):w305-16.
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  118. Schneeweiss S, Avorn J. Antipsychotic agents and sudden cardiac death--how should we manage the risk? N Engl J Med. 2009 Jan 15; 360(3):294-6.
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  119. Rassen JA, Schneeweiss S. Outcomes in the era of bare-metal stents vs the era of drug-eluting stents. JAMA. 2009 Jan 7; 301(1):33-4; author reply 34.
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  120. Schneeweiss S, Setoguchi S, Brookhart MA, Kaci L, Wang PS. Assessing residual confounding of the association between antipsychotic medications and risk of death using survey data. CNS Drugs. 2009; 23(2):171-80.
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  121. Shrank WH, Patrick AR, Pedan A, Polinski JM, Varasteh L, Levin R, Liu N, Schneeweiss S. The effect of transitioning to medicare part d drug coverage in seniors dually eligible for medicare and medicaid. J Am Geriatr Soc. 2008 Dec; 56(12):2304-10.
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  122. Rassen JA, Schneeweiss S, Glynn RJ, Mittleman MA, Brookhart MA. Instrumental variable analysis for estimation of treatment effects with dichotomous outcomes. Am J Epidemiol. 2009 Feb 1; 169(3):273-84.
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  123. Solomon DH, Hochberg MC, Mogun H, Schneeweiss S. The relation between bisphosphonate use and non-union of fractures of the humerus in older adults. Osteoporos Int. 2009 Jun; 20(6):895-901.
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  124. Stolk P, Schneeweiss S, Leufkens HG, Heerdink ER. Impact analysis of the discontinuation of reimbursement: the case of oral contraceptives. Contraception. 2008 Nov; 78(5):399-404.
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  125. Ting G, Schneeweiss S, Scranton R, Katz JN, Weinblatt ME, Young M, Avorn J, Solomon DH. Development of a health care utilisation data-based index for rheumatoid arthritis severity: a preliminary study. Arthritis Res Ther. 2008; 10(4):R95.
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  126. Solomon DH, Glynn RJ, Rothman KJ, Schneeweiss S, Setoguchi S, Mogun H, Avorn J, Stürmer T. Subgroup analyses to determine cardiovascular risk associated with nonsteroidal antiinflammatory drugs and coxibs in specific patient groups. Arthritis Rheum. 2008 Aug 15; 59(8):1097-104.
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  127. Dormuth CR, Schneeweiss S, Brookhart AM, Carney G, Bassett K, Adams S, Wright JM. Frequency and predictors of tablet splitting in statin prescriptions: a population-based analysis. Open Med. 2008; 2(3):e74-82.
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  128. Setoguchi S, Wang PS, Alan Brookhart M, Canning CF, Kaci L, Schneeweiss S. Potential causes of higher mortality in elderly users of conventional and atypical antipsychotic medications. J Am Geriatr Soc. 2008 Sep; 56(9):1644-50.
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  129. Polinski JM, Maclure M, Marshall B, Cassels A, Agnew-Blais J, Patrick AR, Schneeweiss S. Does knowledge of medication prices predict physicians' support for cost effective prescribing policies. Can J Clin Pharmacol. 2008; 15(2):e286-94.
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  130. Schneeweiss S, Walker AM, Seeger JD. Effect of aprotinin on renal dysfunction. Lancet. 2008 Jul 5; 372(9632):26; author reply 26-7.
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  131. Gellad WF, Schneeweiss S, Brawarsky P, Lipsitz S, Haas JS. What if the federal government negotiated pharmaceutical prices for seniors? An estimate of national savings. J Gen Intern Med. 2008 Sep; 23(9):1435-40.
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  132. Setoguchi S, Schneeweiss S, Avorn J, Katz JN, Weinblatt ME, Levin R, Solomon DH. Tumor necrosis factor-alpha antagonist use and heart failure in elderly patients with rheumatoid arthritis. Am Heart J. 2008 Aug; 156(2):336-41.
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  133. Choudhry NK, Brennan T, Toscano M, Spettell C, Glynn RJ, Rubino M, Schneeweiss S, Brookhart AM, Fernandes J, Mathew S, Christiansen B, Antman EM, Avorn J, Shrank WH. Rationale and design of the Post-MI FREEE trial: a randomized evaluation of first-dollar drug coverage for post-myocardial infarction secondary preventive therapies. Am Heart J. 2008 Jul; 156(1):31-6.
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  134. Setoguchi S, Schneeweiss S, Brookhart MA, Glynn RJ, Cook EF. Evaluating uses of data mining techniques in propensity score estimation: a simulation study. Pharmacoepidemiol Drug Saf. 2008 Jun; 17(6):546-55.
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  135. Brookhart MA, Schneeweiss S, Avorn J, Bradbury BD, Rothman KJ, Fischer M, Mehta J, Winkelmayer WC. The effect of altitude on dosing and response to erythropoietin in ESRD. J Am Soc Nephrol. 2008 Jul; 19(7):1389-95.
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  136. Wang PS, Patrick AR, Dormuth CR, Avorn J, Maclure M, Canning CF, Schneeweiss S. The impact of cost sharing on antidepressant use among older adults in British Columbia. Psychiatr Serv. 2008 Apr; 59(4):377-83.
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  137. Solomon DH, Lunt M, Schneeweiss S. The risk of infection associated with tumor necrosis factor alpha antagonists: making sense of epidemiologic evidence. Arthritis Rheum. 2008 Apr; 58(4):919-28.
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  138. Schneeweiss S, Seeger JD, Landon J, Walker AM. Aprotinin during coronary-artery bypass grafting and risk of death. N Engl J Med. 2008 Feb 21; 358(8):771-83.
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  139. van Wijk BL, Shrank WH, Klungel OH, Schneeweiss S, Brookhart MA, Avorn J. A cross-national study of the persistence of antihypertensive medication use in the elderly. J Hypertens. 2008 Jan; 26(1):145-53.
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  140. Dormuth CR, Maclure M, Glynn RJ, Neumann P, Brookhart AM, Schneeweiss S. Emergency hospital admissions after income-based deductibles and prescription copayments in older users of inhaled medications. Clin Ther. 2008; 30 Spec No:1038-50.
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  141. Wang PS, Schneeweiss S, Setoguchi S, Patrick A, Avorn J, Mogun H, Choudhry NK, Brookhart MA. Ventricular arrhythmias and cerebrovascular events in the elderly using conventional and atypical antipsychotic medications. J Clin Psychopharmacol. 2007 Dec; 27(6):707-10.
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  142. Stürmer T, Glynn RJ, Rothman KJ, Avorn J, Schneeweiss S. Adjustments for unmeasured confounders in pharmacoepidemiologic database studies using external information. Med Care. 2007 Oct; 45(10 Supl 2):S158-65.
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  143. Schneeweiss S, Patrick AR, Stürmer T, Brookhart MA, Avorn J, Maclure M, Rothman KJ, Glynn RJ. Increasing levels of restriction in pharmacoepidemiologic database studies of elderly and comparison with randomized trial results. Med Care. 2007 Oct; 45(10 Supl 2):S131-42.
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  144. Brookhart MA, Rassen JA, Wang PS, Dormuth C, Mogun H, Schneeweiss S. Evaluating the validity of an instrumental variable study of neuroleptics: can between-physician differences in prescribing patterns be used to estimate treatment effects? Med Care. 2007 Oct; 45(10 Supl 2):S116-22.
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  145. Maclure M, Carleton B, Schneeweiss S. Designed delays versus rigorous pragmatic trials: lower carat gold standards can produce relevant drug evaluations. Med Care. 2007 Oct; 45(10 Supl 2):S44-9.
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  146. Schmajuk G, Schneeweiss S, Katz JN, Weinblatt ME, Setoguchi S, Avorn J, Levin R, Solomon DH. Treatment of older adult patients diagnosed with rheumatoid arthritis: improved but not optimal. Arthritis Rheum. 2007 Aug 15; 57(6):928-34.
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  147. Setoguchi S, Stevenson LW, Schneeweiss S. Repeated hospitalizations predict mortality in the community population with heart failure. Am Heart J. 2007 Aug; 154(2):260-6.
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  148. Schneeweiss S, Patrick AR, Maclure M, Dormuth CR, Glynn RJ. Adherence to beta-blocker therapy under drug cost-sharing in patients with and without acute myocardial infarction. Am J Manag Care. 2007 Aug; 13(8):445-52.
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  149. Pedan A, Varasteh L, Schneeweiss S. Analysis of factors associated with statin adherence in a hierarchical model considering physician, pharmacy, patient, and prescription characteristics. J Manag Care Pharm. 2007 Jul-Aug; 13(6):487-96.
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  150. Schneeweiss S. Developments in post-marketing comparative effectiveness research. Clin Pharmacol Ther. 2007 Aug; 82(2):143-56.
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  151. Schneeweiss S, Setoguchi S, Weinblatt ME, Katz JN, Avorn J, Sax PE, Levin R, Solomon DH. Anti-tumor necrosis factor alpha therapy and the risk of serious bacterial infections in elderly patients with rheumatoid arthritis. Arthritis Rheum. 2007 Jun; 56(6):1754-64.
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  152. Brookhart MA, Patrick AR, Schneeweiss S, Avorn J, Dormuth C, Shrank W, van Wijk BL, Cadarette SM, Canning CF, Solomon DH. Physician follow-up and provider continuity are associated with long-term medication adherence: a study of the dynamics of statin use. Arch Intern Med. 2007 Apr 23; 167(8):847-52.
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  153. Setoguchi S, Solomon DH, Glynn RJ, Cook EF, Levin R, Schneeweiss S. Agreement of diagnosis and its date for hematologic malignancies and solid tumors between medicare claims and cancer registry data. Cancer Causes Control. 2007 Jun; 18(5):561-9.
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  154. Schneeweiss S, Patrick AR, Maclure M, Dormuth CR, Glynn RJ. Adherence to statin therapy under drug cost sharing in patients with and without acute myocardial infarction: a population-based natural experiment. Circulation. 2007 Apr 24; 115(16):2128-35.
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  155. Stürmer T, Schneeweiss S, Rothman KJ, Avorn J, Glynn RJ. Performance of propensity score calibration--a simulation study. Am J Epidemiol. 2007 May 15; 165(10):1110-8.
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  156. Dixon E, Schneeweiss S, Pasieka JL, Bathe OF, Sutherland F, Doig C. Mortality following liver resection in US medicare patients: does the presence of a liver transplant program affect outcome? J Surg Oncol. 2007 Mar 1; 95(3):194-200.
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  157. Schneeweiss S, Setoguchi S, Brookhart A, Dormuth C, Wang PS. Risk of death associated with the use of conventional versus atypical antipsychotic drugs among elderly patients. CMAJ. 2007 Feb 27; 176(5):627-32.
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  158. Schneeweiss S. Understanding secondary databases: a commentary on "Sources of bias for health state characteristics in secondary databases". J Clin Epidemiol. 2007 Jul; 60(7):648-50.
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  159. Stürmer T, Schneeweiss S, Rothman KJ, Avorn J, Glynn RJ. Propensity Score Calibration and its Alternatives. Am J Epidemiol. 2007; 165(10):1122-1123.
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  160. Brookhart MA, Schneeweiss S. Preference-based instrumental variable methods for the estimation of treatment effects: assessing validity and interpreting results. Int J Biostat. 2007; 3(1):Article 14.
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  161. Choudhry NK, Avorn J, Antman EM, Schneeweiss S, Shrank WH. Should patients receive secondary prevention medications for free after a myocardial infarction? An economic analysis. Health Aff (Millwood). 2007 Jan-Feb; 26(1):186-94.
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  162. Schneeweiss S, Robicsek A, Scranton R, Zuckerman D, Solomon DH. Veteran's affairs hospital discharge databases coded serious bacterial infections accurately. J Clin Epidemiol. 2007 Apr; 60(4):397-409.
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  163. Setoguchi S, Glynn RJ, Avorn J, Mogun H, Schneeweiss S. Statins and the risk of lung, breast, and colorectal cancer in the elderly. Circulation. 2007 Jan 2; 115(1):27-33.
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  164. Winkelmayer WC, Fischer MA, Schneeweiss S, Levin R, Avorn J. Angiotensin inhibition after myocardial infarction: does drug class matter? J Gen Intern Med. 2006 Dec; 21(12):1242-7.
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  165. Solomon DH, Avorn J, Katz JN, Weinblatt ME, Setoguchi S, Levin R, Schneeweiss S. Immunosuppressive medications and hospitalization for cardiovascular events in patients with rheumatoid arthritis. Arthritis Rheum. 2006 Dec; 54(12):3790-8.
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  166. Schneeweiss S, Solomon DH, Wang PS, Rassen J, Brookhart MA. Simultaneous assessment of short-term gastrointestinal benefits and cardiovascular risks of selective cyclooxygenase 2 inhibitors and nonselective nonsteroidal antiinflammatory drugs: an instrumental variable analysis. Arthritis Rheum. 2006 Nov; 54(11):3390-8.
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  167. Wang PS, Brookhart MA, Setoguchi S, Patrick AR, Schneeweiss S. Psychotropic medication use for behavioral symptoms of dementia. Curr Neurol Neurosci Rep. 2006 Nov; 6(6):490-5.
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  168. Setoguchi S, Solomon DH, Weinblatt ME, Katz JN, Avorn J, Glynn RJ, Cook EF, Carney G, Schneeweiss S. Tumor necrosis factor alpha antagonist use and cancer in patients with rheumatoid arthritis. Arthritis Rheum. 2006 Sep; 54(9):2757-64.
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  169. Schneeweiss S, Solomon DH. Not-so-surprising findings. CMAJ. 2006 Jul 18; 175(2):171-2; author reply 172.
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  170. Brookhart MA, Wang PS, Solomon DH, Schneeweiss S. Instrumental variable analysis of secondary pharmacoepidemiologic data. Epidemiology. 2006 Jul; 17(4):373-4.
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  171. Fischer MA, Cheng H, Schneeweiss S, Avorn J, Solomon DH. Prior authorization policies for selective cyclooxygenase-2 inhibitors in Medicaid: a policy review. Med Care. 2006 Jul; 44(7):658-63.
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  172. Solomon DH, Goodson NJ, Katz JN, Weinblatt ME, Avorn J, Setoguchi S, Canning C, Schneeweiss S. Patterns of cardiovascular risk in rheumatoid arthritis. Ann Rheum Dis. 2006 Dec; 65(12):1608-12.
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  173. Schneeweiss S. Reference drug programs: effectiveness and policy implications. Health Policy. 2007 Apr; 81(1):17-28.
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  174. Dormuth CR, Glynn RJ, Neumann P, Maclure M, Brookhart AM, Schneeweiss S. Impact of two sequential drug cost-sharing policies on the use of inhaled medications in older patients with chronic obstructive pulmonary disease or asthma. Clin Ther. 2006 Jun; 28(6):964-78; discussion 962-3.
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  175. Glynn RJ, Schneeweiss S, Wang PS, Levin R, Avorn J. Selective prescribing led to overestimation of the benefits of lipid-lowering drugs. J Clin Epidemiol. 2006 Aug; 59(8):819-28.
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  176. Schneeweiss S. Sensitivity analysis and external adjustment for unmeasured confounders in epidemiologic database studies of therapeutics. Pharmacoepidemiol Drug Saf. 2006 May; 15(5):291-303.
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  177. Solomon DH, Avorn J, Stürmer T, Glynn RJ, Mogun H, Schneeweiss S. Cardiovascular outcomes in new users of coxibs and nonsteroidal antiinflammatory drugs: high-risk subgroups and time course of risk. Arthritis Rheum. 2006 May; 54(5):1378-89.
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  178. Winkelmayer WC, Benner JS, Glynn RJ, Schneeweiss S, Wang PS, Brookhart MA, Levin R, Jackson JD, Avorn J. Assessing health state utilities in elderly patients at cardiovascular risk. Med Decis Making. 2006 May-Jun; 26(3):247-54.
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  179. Brookhart MA, Wang PS, Solomon DH, Schneeweiss S. Evaluating short-term drug effects using a physician-specific prescribing preference as an instrumental variable. Epidemiology. 2006 May; 17(3):268-75.
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  180. Brookhart MA, Schneeweiss S, Rothman KJ, Glynn RJ, Avorn J, Stürmer T. Variable selection for propensity score models. Am J Epidemiol. 2006 Jun 15; 163(12):1149-56.
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  181. Schneeweiss S, Maclure M, Dormuth CR, Glynn RJ, Canning C, Avorn J. A therapeutic substitution policy for proton pump inhibitors: clinical and economic consequences. Clin Pharmacol Ther. 2006 Apr; 79(4):379-88.
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  182. Sato M, Schneeweiss S, Scranton R, Katz JN, Weinblatt ME, Avorn J, Ting G, Shadick NA, Solomon DH. The validity of a rheumatoid arthritis medical records-based index of severity compared with the DAS28. Arthritis Res Ther. 2006; 8(3):R57.
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  183. Glynn RJ, Schneeweiss S, Stürmer T. Indications for propensity scores and review of their use in pharmacoepidemiology. Basic Clin Pharmacol Toxicol. 2006 Mar; 98(3):253-9.
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  184. Maclure M, Nguyen A, Carney G, Dormuth C, Roelants H, Ho K, Schneeweiss S. Measuring prescribing improvements in pragmatic trials of educational tools for general practitioners. Basic Clin Pharmacol Toxicol. 2006 Mar; 98(3):243-52.
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  185. Schneeweiss S. Methods in pharmacoepidemiology: time-varying drug effects revisited. Pharmacoepidemiol Drug Saf. 2006 Feb; 15(2):93-4.
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  186. Thacker EL, Schneeweiss S. Initiation of acetylcholinesterase inhibitors and complications of chronic airways disorders in elderly patients. Drug Saf. 2006; 29(11):1077-85.
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  187. Kinjo M, Setoguchi S, Schneeweiss S, Solomon DH. Bone mineral density in subjects using central nervous system-active medications. Am J Med. 2005 Dec; 118(12):1414.
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  188. Winkelmayer WC, Fischer MA, Schneeweiss S, Wang PS, Levin R, Avorn J. Underuse of ACE inhibitors and angiotensin II receptor blockers in elderly patients with diabetes. Am J Kidney Dis. 2005 Dec; 46(6):1080-7.
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  189. Wang PS, Schneeweiss S, Avorn J, Fischer MA, Mogun H, Solomon DH, Brookhart MA. Risk of death in elderly users of conventional vs. atypical antipsychotic medications. N Engl J Med. 2005 Dec 1; 353(22):2335-41.
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  190. Brookhart MA, Solomon DH, Wang P, Glynn RJ, Avorn J, Schneeweiss S. Explained variation in a model of therapeutic decision making is partitioned across patient, physician, and clinic factors. J Clin Epidemiol. 2006 Jan; 59(1):18-25.
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  191. Stürmer T, Joshi M, Glynn RJ, Avorn J, Rothman KJ, Schneeweiss S. A review of the application of propensity score methods yielded increasing use, advantages in specific settings, but not substantially different estimates compared with conventional multivariable methods. J Clin Epidemiol. 2006 May; 59(5):437-47.
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  192. Perlis RH, Ganz DA, Avorn J, Schneeweiss S, Glynn RJ, Smoller JW, Wang PS. Pharmacogenetic testing in the clinical management of schizophrenia: a decision-analytic model. J Clin Psychopharmacol. 2005 Oct; 25(5):427-34.
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  193. Setoguchi S, Avorn J, Schneeweiss S. Statins and the risk of colorectal cancer. N Engl J Med. 2005 Sep 1; 353(9):952-4; author reply 952-4.
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  194. Ting G, Schneeweiss S, Katz JN, Weinblatt ME, Cabral D, Scranton RE, Solomon DH. Performance of a rheumatoid arthritis records-based index of severity. J Rheumatol. 2005 Sep; 32(9):1679-87.
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  195. Winkelmayer WC, Schneeweiss S, Mogun H, Patrick AR, Avorn J, Solomon DH. Identification of individuals with CKD from Medicare claims data: a validation study. Am J Kidney Dis. 2005 Aug; 46(2):225-32.
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  196. Avorn J, Schneeweiss S, Sudarsky LR, Benner J, Kiyota Y, Levin R, Glynn RJ. Sudden uncontrollable somnolence and medication use in Parkinson disease. Arch Neurol. 2005 Aug; 62(8):1242-8.
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  197. Schneeweiss S. Methods in pharmacoepidemiology: an invited series. Pharmacoepidemiol Drug Saf. 2005 Jul; 14(7):453-4.
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  198. Stürmer T, Schneeweiss S, Avorn J, Glynn RJ. Adjusting effect estimates for unmeasured confounding with validation data using propensity score calibration. Am J Epidemiol. 2005 Aug 1; 162(3):279-89.
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  199. Wang PS, Avorn J, Brookhart MA, Mogun H, Schneeweiss S, Fischer MA, Glynn RJ. Effects of noncardiovascular comorbidities on antihypertensive use in elderly hypertensives. Hypertension. 2005 Aug; 46(2):273-9.
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  200. Schneeweiss S, Wang PS. Claims data studies of sedative-hypnotics and hip fractures in older people: exploring residual confounding using survey information. J Am Geriatr Soc. 2005 Jun; 53(6):948-54.
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  201. Stürmer T, Schneeweiss S, Brookhart MA, Rothman KJ, Avorn J, Glynn RJ. Analytic strategies to adjust confounding using exposure propensity scores and disease risk scores: nonsteroidal antiinflammatory drugs and short-term mortality in the elderly. Am J Epidemiol. 2005 May 1; 161(9):891-8.
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  202. Wang PS, Schneeweiss S, Brookhart MA, Glynn RJ, Mogun H, Patrick AR, Avorn J. Suboptimal antidepressant use in the elderly. J Clin Psychopharmacol. 2005 Apr; 25(2):118-26.
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  203. Schneeweiss S, Avorn J. A review of uses of health care utilization databases for epidemiologic research on therapeutics. J Clin Epidemiol. 2005 Apr; 58(4):323-37.
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  204. Wilson SE, Leonard A, Moomaw C, Schneeweiss S, Eckman MH. Underuse of controller medications among children with persistent asthma in the Ohio medicaid population: evolving differences with new medications. Ambul Pediatr. 2005 Mar-Apr; 5(2):83-9.
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  205. Schneeweiss S, Glynn RJ, Avorn J, Solomon DH. A Medicare database review found that physician preferences increasingly outweighed patient characteristics as determinants of first-time prescriptions for COX-2 inhibitors. J Clin Epidemiol. 2005 Jan; 58(1):98-102.
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  206. Schneeweiss S, Glynn RJ, Tsai EH, Avorn J, Solomon DH. Adjusting for unmeasured confounders in pharmacoepidemiologic claims data using external information: the example of COX2 inhibitors and myocardial infarction. Epidemiology. 2005 Jan; 16(1):17-24.
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  207. Dormuth CR, Burnett S, Schneeweiss S. Using policy simulation to predict drug plan expenditure when planning reimbursement changes. Pharmacoeconomics. 2005; 23(10):1021-30.
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  208. Schneeweiss S, Wang PS. Association between SSRI use and hip fractures and the effect of residual confounding bias in claims database studies. J Clin Psychopharmacol. 2004 Dec; 24(6):632-8.
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  209. Fischer MA, Schneeweiss S, Avorn J, Solomon DH. Medicaid prior-authorization programs and the use of cyclooxygenase-2 inhibitors. N Engl J Med. 2004 Nov 18; 351(21):2187-94.
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  210. Jacobus S, Schneeweiss S, Chan KA. Exposure misclassification as a result of free sample drug utilization in automated claims databases and its effect on a pharmacoepidemiology study of selective COX-2 inhibitors. Pharmacoepidemiol Drug Saf. 2004 Oct; 13(10):695-702.
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  211. Avorn J, Knight E, Ganz DA, Schneeweiss S. Therapeutic delay and reduced functional status six months after thrombolysis for acute myocardial infarction. Am J Cardiol. 2004 Aug 15; 94(4):415-20.
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  212. Schneeweiss S, Dormuth C, Grootendorst P, Soumerai SB, Maclure M. Net health plan savings from reference pricing for angiotensin-converting enzyme inhibitors in elderly British Columbia residents. Med Care. 2004 Jul; 42(7):653-60.
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  213. Kiyota Y, Schneeweiss S, Glynn RJ, Cannuscio CC, Avorn J, Solomon DH. Accuracy of Medicare claims-based diagnosis of acute myocardial infarction: estimating positive predictive value on the basis of review of hospital records. Am Heart J. 2004 Jul; 148(1):99-104.
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  214. Solomon DH, Schneeweiss S, Levin R, Avorn J. Relationship between COX-2 specific inhibitors and hypertension. Hypertension. 2004 Aug; 44(2):140-5.
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  215. Schneeweiss S, Wang PS, Avorn J, Maclure M, Levin R, Glynn RJ. Consistency of performance ranking of comorbidity adjustment scores in Canadian and U.S. utilization data. J Gen Intern Med. 2004 May; 19(5 Pt 1):444-50.
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  216. Solomon DH, Schneeweiss S, Glynn RJ, Kiyota Y, Levin R, Mogun H, Avorn J. Relationship between selective cyclooxygenase-2 inhibitors and acute myocardial infarction in older adults. Circulation. 2004 May 4; 109(17):2068-73.
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  217. Wang PS, Schneeweiss S, Glynn RJ, Mogun H, Avorn J. Use of the case-crossover design to study prolonged drug exposures and insidious outcomes. Ann Epidemiol. 2004 Apr; 14(4):296-303.
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  218. Katsarava Z, Schneeweiss S, Kurth T, Kroener U, Fritsche G, Eikermann A, Diener HC, Limmroth V. Incidence and predictors for chronicity of headache in patients with episodic migraine. Neurology. 2004 Mar 9; 62(5):788-90.
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  219. Schneeweiss S, Maclure M, Carleton B, Glynn RJ, Avorn J. Clinical and economic consequences of a reimbursement restriction of nebulised respiratory therapy in adults: direct comparison of randomised and observational evaluations. BMJ. 2004 Mar 6; 328(7439):560.
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  220. Solomon DH, Schneeweiss S, Glynn RJ, Levin R, Avorn J. Determinants of selective cyclooxygenase-2 inhibitor prescribing: are patient or physician characteristics more important? Am J Med. 2003 Dec 15; 115(9):715-20.
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  221. Schneeweiss S, Soumerai SB, Maclure M, Dormuth C, Walker AM, Glynn RJ. Clinical and economic consequences of reference pricing for dihydropyridine calcium channel blockers. Clin Pharmacol Ther. 2003 Oct; 74(4):388-400.
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  222. Schneeweiss S, Wang PS, Avorn J, Glynn RJ. Improved comorbidity adjustment for predicting mortality in Medicare populations. Health Serv Res. 2003 Aug; 38(4):1103-20.
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  223. Taxis K, Schneeweiss S. Frequency and predictors of drug therapy interruptions after hospital discharge under physician drug budgets in Germany. Int J Clin Pharmacol Ther. 2003 Feb; 41(2):77-82.
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  224. Ess SM, Schneeweiss S, Szucs TD. European healthcare policies for controlling drug expenditure. Pharmacoeconomics. 2003; 21(2):89-103.
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  225. Duetz MS, Schneeweiss S, Maclure M, Abel T, Glynn RJ, Soumerai SB. Physician gender and changes in drug prescribing after the implementation of reference pricing in British Columbia. Clin Ther. 2003 Jan; 25(1):273-84.
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  226. Schneeweiss S, Manstetten A, Wildner M, Sangha O, Liebetrau M, Paeger A. Costs of measuring outcomes of acute hospital care in a longitudinal outcomes measurement system. Am J Med Qual. 2003 Jan-Feb; 18(1):3-9.
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  227. Avorn J, Benner J, Ford I, Ganz DA, Gaw A, Glynn RJ, Jackson J, Lagaay AM, Schneeweiss S, Walley T, Wang PS. Measuring the cost-effectiveness of lipid-lowering drugs in the elderly: the outcomes research and economic analysis components of the PROSPER trial. Control Clin Trials. 2002 Dec; 23(6):757-73.
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  228. Sangha O, Schneeweiss S, Wildner M, Cook EF, Brennan TA, Witte J, Liang MH. Metric properties of the appropriateness evaluation protocol and predictors of inappropriate hospital use in Germany: an approach using longitudinal patient data. Int J Qual Health Care. 2002 Dec; 14(6):483-92.
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  229. Schneeweiss S, Maclure M, Dormuth C, Avorn J. Pharmaceutical cost containment with reference-based pricing: time for refinements. CMAJ. 2002 Nov 26; 167(11):1250-1.
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  230. Schneeweiss S, Maclure M, Soumerai SB, Walker AM, Glynn RJ. Quasi-experimental longitudinal designs to evaluate drug benefit policy changes with low policy compliance. J Clin Epidemiol. 2002 Aug; 55(8):833-41.
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  231. Schneeweiss S, Soumerai SB, Maclure M. Reference drug pricing. CMAJ. 2002 Jul 23; 167(2):126-7; author reply 127-8.
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  232. Schneeweiss S, Hasford J, Göttler M, Hoffmann A, Riethling AK, Avorn J. Admissions caused by adverse drug events to internal medicine and emergency departments in hospitals: a longitudinal population-based study. Eur J Clin Pharmacol. 2002 Jul; 58(4):285-91.
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  233. Wang PS, Glynn RJ, Ganz DA, Schneeweiss S, Levin R, Avorn J. Clozapine use and risk of diabetes mellitus. J Clin Psychopharmacol. 2002 Jun; 22(3):236-43.
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  234. Schneeweiss S, Soumerai SB, Glynn RJ, Maclure M, Dormuth C, Walker AM. Impact of reference-based pricing for angiotensin-converting enzyme inhibitors on drug utilization. CMAJ. 2002 Mar 19; 166(6):737-45.
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  235. Schneeweiss S, Walker AM, Glynn RJ, Maclure M, Dormuth C, Soumerai SB. Outcomes of reference pricing for angiotensin-converting-enzyme inhibitors. N Engl J Med. 2002 Mar 14; 346(11):822-9.
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  236. Schneeweiss S, Maclure M, Soumerai SB. Prescription duration after drug copay changes in older people: methodological aspects. J Am Geriatr Soc. 2002 Mar; 50(3):521-5.
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  237. Sangha O, Schneeweiss S. [Outcomes count: the importance of measuring the outcomes of hospital care]. Z Arztl Fortbild Qualitatssich. 2002 Jan; 96(1):53-7.
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  238. Schneeweiss S, Seeger JD, Maclure M, Wang PS, Avorn J, Glynn RJ. Performance of comorbidity scores to control for confounding in epidemiologic studies using claims data. Am J Epidemiol. 2001 Nov 1; 154(9):854-64.
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  239. Schneeweiss S, Sangha O. [Provider profiling: needs, methodologic requirements and means to increase acceptance]. Dtsch Med Wochenschr. 2001 Aug 17; 126(33):918-24.
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  240. Schneeweiss S, Göttler M, Hasford J, Swoboda W, Hippius M, Hoffmann AK, Riethling AK, Krappweis J. First results from an intensified monitoring system to estimate drug related hospital admissions. Br J Clin Pharmacol. 2001 Aug; 52(2):196-200.
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  241. Schneeweiss S, Sangha O, Manstetten A. [Patient-centered evaluation of the health status in a longitudinal quality management system in the hospital]. Gesundheitswesen. 2001 Apr; 63(4):205-11.
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  242. Schneeweiss S, Maclure M, Walker AM, Grootendorst P, Soumerai SB. On the evaluation of drug benefits policy changes with longitudinal claims data: the policy maker's versus the clinician's perspective. Health Policy. 2001 Feb; 55(2):97-109.
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  243. Schneeweiss S, Sangha O. [An update of the German version of AEP (Appropriateness Evaluation Protocol): metric properties and practical experiences]. Chirurg. 2001 Feb; 72(2):196-8.
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  244. Peters U, Schneeweiss S, Trautwein EA, Erbersdobler HF. A case-control study of the effect of infant feeding on celiac disease. Ann Nutr Metab. 2001; 45(4):135-42.
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  245. Maclure M, Schneeweiss S. Causation of bias: the episcope. Epidemiology. 2001 Jan; 12(1):114-22.
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  246. Schneeweiss S, Maclure M. Use of comorbidity scores for control of confounding in studies using administrative databases. Int J Epidemiol. 2000 Oct; 29(5):891-8.
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  247. Schneeweiss S, Sangha O, Siebert H, Hebeisen H, Hübner M, Heinrich R, Wildner M, Witte J. [Evaluation of the appropriateness of hospital care in internal medicine. Reliability of a German adaptation of the procedure]. Dtsch Med Wochenschr. 2000 Jul 28; 125(30):894-9.
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  248. Schneeweiss S, Sangha O, Wildner M, Siebert H, Hübner M, Witte J. [Corroboration of concurrent assessment of inappropriate hospitalization with retrospective evaluation based on patient records]. Gesundheitswesen. 2000 Apr; 62(4):207-10.
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  249. Rich S, Rubin L, Walker AM, Schneeweiss S, Abenhaim L. Anorexigens and pulmonary hypertension in the United States: results from the surveillance of North American pulmonary hypertension. Chest. 2000 Mar; 117(3):870-4.
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  250. Schneeweiss S. Sensitivity analysis of the diagnostic value of endoscopies in cross-sectional studies in the absence of a gold standard. Int J Technol Assess Health Care. 2000; 16(3):834-41.
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  251. Schneeweiss S, Kriegmair M, Stepp H. Is everything all right if nothing seems wrong? A simple method of assessing the diagnostic value of endoscopic procedures when a gold standard is absent. J Urol. 1999 Apr; 161(4):1116-9.
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  252. Schneeweiss S, Schöffski O, Selke GW. What is Germany's experience on reference based drug pricing and the etiology of adverse health outcomes or substitution? Health Policy. 1998 Jun; 44(3):253-60.
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  253. Schneeweiss S, Stürmer T, Maclure M. Case-crossover and case-time-control designs as alternatives in pharmacoepidemiologic research. Pharmacoepidemiol Drug Saf. 1997 Oct; 6 Suppl 3:S51-9.
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  254. Schneeweiss SG, Goettler M, Hasford J. Adverse drug events in hospitalized patients. JAMA. 1997 May 7; 277(17):1352-3; author reply 1353-4.
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  255. Jüngst D, del Pozo R, Dolu MH, Schneeweiss SG, Frimberger E. Rapid formation of cholesterol crystals in gallbladder bile is associated with stone recurrence after laparoscopic cholecystotomy. Hepatology. 1997 Mar; 25(3):509-13.
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  256. Spiegelman D, Schneeweiss S, McDermott A. Measurement error correction for logistic regression models with an "alloyed gold standard". Am J Epidemiol. 1997 Jan 15; 145(2):184-96.
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  257. Korell M, Schmaus F, Strowitzki T, Schneeweiss SG, Hepp H. Pain intensity following laparoscopy. Surg Laparosc Endosc. 1996 Oct; 6(5):375-9.
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  258. Müller-Höcker J, Aust D, Napiwotzky J, Münscher C, Link TA, Seibel P, Schneeweiss SG, Kadenbach B. Defects of the respiratory chain in oxyphil and chief cells of the normal parathyroid and in hyperfunction. Hum Pathol. 1996 Jun; 27(6):532-41.
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