Contact, publication, and social network information about Harvard faculty and fellows. Harvard Catalyst Profiles
Keywords
Last Name
Institution

Raif Salim Geha, M.D.

TitleJames L. Gamble Professor of Pediatrics
InstitutionChildren's Hospital Boston
DepartmentPediatrics
AddressChildren's Hospital
Immunology Division - KARP 10th Floor
1 Blackfan Circle
Boston MA 02115
Phone617/355-7602
Fax617/730-0528

 Mentoring 
 completed student projects
Changes in Immune Response to Co-Application of Antigen and CpG-Oligodeoxynucleotide in Epicutaneously Sensitized Skin of Balb/C Mice
Part Time, 04/02/07 - 04/01/08

 Research 
 research resources
This researcher has shared information about their research resources
in the eagle-i Network. To update or add resource records, contact
eagle-i@hms.harvard.edu.
Geha Lab - Mouse strains (4)

 Bibliographic 
 selected publications
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
List All   |   Timeline
  1. Jabara HH, Ohsumi T, Chou J, Massaad MJ, Benson H, Megarbane A, Chouery E, Mikhael R, Gorka O, Gewies A, Portales P, Nakayama T, Hosokawa H, Revy P, Herrod H, Le Deist F, Lefranc G, Ruland J, Geha RS. A homozygous mucosa-associated lymphoid tissue 1 (MALT1) mutation in a family with combined immunodeficiency. J Allergy Clin Immunol. 2013 Jul; 132(1):151-8.
    View in: PubMed
  2. Kumar L, Lu B, Gerard C, Geha RS. C3a receptor promotes viral containment in mice inoculated with vaccinia virus at sites of allergic skin inflammation. J Allergy Clin Immunol. 2013 Sep; 132(3):746-748.e3.
    View in: PubMed
  3. Watanabe Y, Sasahara Y, Ramesh N, Massaad MJ, Yeng Looi C, Kumaki S, Kure S, Geha RS, Tsuchiya S. T-cell receptor ligation causes Wiskott-Aldrich syndrome protein degradation and F-actin assembly downregulation. J Allergy Clin Immunol. 2013 Sep; 132(3):648-655.e1.
    View in: PubMed
  4. Bousfiha AA, Jeddane L, Ailal F, Al Herz W, Conley ME, Cunningham-Rundles C, Etzioni A, Fischer A, Franco JL, Geha RS, Hammarström L, Nonoyama S, Ochs HD, Roifman CM, Seger R, Tang ML, Puck JM, Chapel H, Notarangelo LD, Casanova JL. A Phenotypic Approach for IUIS PID Classification and Diagnosis: Guidelines for Clinicians at the Bedside. J Clin Immunol. 2013 Aug; 33(6):1078-87.
    View in: PubMed
  5. Leisten S, Oyoshi MK, Galand C, Hornick JL, Gurish MF, Geha RS. Development of skin lesions in filaggrin-deficient mice is dependent on adaptive immunity. J Allergy Clin Immunol. 2013 Apr; 131(4):1247-1250.e1.
    View in: PubMed
  6. Massaad MJ, Ramesh N, Geha RS. Wiskott-Aldrich syndrome: a comprehensive review. Ann N Y Acad Sci. 2013 May; 1285(1):26-43.
    View in: PubMed
  7. Mizesko MC, Banerjee PP, Monaco-Shawver L, Mace EM, Bernal WE, Sawalle-Belohradsky J, Belohradsky BH, Heinz V, Freeman AF, Sullivan KE, Holland SM, Torgerson TR, Al-Herz W, Chou J, Hanson IC, Albert MH, Geha RS, Renner ED, Orange JS. Defective actin accumulation impairs human natural killer cell function in patients with dedicator of cytokinesis 8 deficiency. J Allergy Clin Immunol. 2013 Mar; 131(3):840-8.
    View in: PubMed
  8. Bartnikas LM, Gurish MF, Burton OT, Leisten S, Janssen E, Oettgen HC, Beaupré J, Lewis CN, Austen KF, Schulte S, Hornick JL, Geha RS, Oyoshi MK. Epicutaneous sensitization results in IgE-dependent intestinal mast cell expansion and food-induced anaphylaxis. J Allergy Clin Immunol. 2013 Feb; 131(2):451-460.e6.
    View in: PubMed
  9. Brauweiler AM, Bin L, Kim BE, Oyoshi MK, Geha RS, Goleva E, Leung DY. Filaggrin-dependent secretion of sphingomyelinase protects against staphylococcal a-toxin-induced keratinocyte death. J Allergy Clin Immunol. 2013 Feb; 131(2):421-427.e2.
    View in: PubMed
  10. Recher M, Fried AJ, Massaad MJ, Kim HY, Rizzini M, Frugoni F, Walter JE, Mathew D, Eibel H, Hess C, Giliani S, Umetsu DT, Notarangelo LD, Geha RS. Intronic SH2D1A mutation with impaired SAP expression and agammaglobulinemia. Clin Immunol. 2013 Feb; 146(2):84-9.
    View in: PubMed
  11. Chou J, Ohsumi TK, Geha RS. Use of whole exome and genome sequencing in the identification of genetic causes of primary immunodeficiencies. Curr Opin Allergy Clin Immunol. 2012 Dec; 12(6):623-8.
    View in: PubMed
  12. Oyoshi MK, He R, Li Y, Mondal S, Yoon J, Afshar R, Chen M, Lee DM, Luo HR, Luster AD, Cho JS, Miller LS, Larson A, Murphy GF, Geha RS. Leukotriene b4-driven neutrophil recruitment to the skin is essential for allergic skin inflammation. Immunity. 2012 Oct 19; 37(4):747-58.
    View in: PubMed
  13. Garber JJ, Takeshima F, Antón IM, Oyoshi MK, Lyubimova A, Kapoor A, Shibata T, Chen F, Alt FW, Geha RS, Leong JM, Snapper SB. Enteropathogenic Escherichia coli and Vaccinia Virus Do Not Require the Family of WASP-Interacting Proteins for Pathogen-Induced Actin Assembly. Infect Immun. 2012 Dec; 80(12):4071-7.
    View in: PubMed
  14. Hidano S, Kitamura D, Kumar L, Geha RS, Goitsuka R. SLP-76 is required for high-affinity IgE receptor- and IL-3 receptor-mediated activation of basophils. Int Immunol. 2012 Nov; 24(11):719-27.
    View in: PubMed
  15. Chou J, Hanna-Wakim R, Tirosh I, Kane J, Fraulino D, Lee YN, Ghanem S, Mahfouz I, Mégarbané A, Lefranc G, Inati A, Dbaibo G, Giliani S, Notarangelo LD, Geha RS, Massaad MJ. A novel homozygous mutation in recombination activating gene 2 in 2 relatives with different clinical phenotypes: Omenn syndrome and hyper-IgM syndrome. J Allergy Clin Immunol. 2012 Dec; 130(6):1414-6.
    View in: PubMed
  16. Alangari A, Alsultan A, Adly N, Massaad MJ, Kiani IS, Aljebreen A, Raddaoui E, Almomen AK, Al-Muhsen S, Geha RS, Alkuraya FS. LPS-responsive beige-like anchor (LRBA) gene mutation in a family with inflammatory bowel disease and combined immunodeficiency. J Allergy Clin Immunol. 2012 Aug; 130(2):481-8.e2.
    View in: PubMed
  17. Jabara HH, McDonald DR, Janssen E, Massaad MJ, Ramesh N, Borzutzky A, Rauter I, Benson H, Schneider L, Baxi S, Recher M, Notarangelo LD, Wakim R, Dbaibo G, Dasouki M, Al-Herz W, Barlan I, Baris S, Kutukculer N, Ochs HD, Plebani A, Kanariou M, Lefranc G, Reisli I, Fitzgerald KA, Golenbock D, Manis J, Keles S, Ceja R, Chatila TA, Geha RS. DOCK8 functions as an adaptor that links TLR-MyD88 signaling to B cell activation. Nat Immunol. 2012 Jun; 13(6):612-20.
    View in: PubMed
  18. Al-Herz W, Ragupathy R, Massaad MJ, Al-Attiyah R, Nanda A, Engelhardt KR, Grimbacher B, Notarangelo L, Chatila T, Geha RS. Clinical, immunologic and genetic profiles of DOCK8-deficient patients in Kuwait. Clin Immunol. 2012 Jun; 143(3):266-72.
    View in: PubMed
  19. Oyoshi MK, He R, Kanaoka Y, ElKhal A, Kawamoto S, Lewis CN, Austen KF, Geha RS. Eosinophil-derived leukotriene C4 signals via type 2 cysteinyl leukotriene receptor to promote skin fibrosis in a mouse model of atopic dermatitis. Proc Natl Acad Sci U S A. 2012 Mar 27; 109(13):4992-7.
    View in: PubMed
  20. Recher M, Burns SO, de la Fuente MA, Volpi S, Dahlberg C, Walter JE, Moffitt K, Mathew D, Honke N, Lang PA, Patrizi L, Falet H, Keszei M, Mizui M, Csizmadia E, Candotti F, Nadeau K, Bouma G, Delmonte OM, Frugoni F, Fomin AB, Buchbinder D, Lundequist EM, Massaad MJ, Tsokos GC, Hartwig J, Manis J, Terhorst C, Geha RS, Snapper S, Lang KS, Malley R, Westerberg L, Thrasher AJ, Notarangelo LD. B cell-intrinsic deficiency of the Wiskott-Aldrich syndrome protein (WASp) causes severe abnormalities of the peripheral B-cell compartment in mice. Blood. 2012 Mar 22; 119(12):2819-28.
    View in: PubMed
  21. Lanzi G, Moratto D, Vairo D, Masneri S, Delmonte O, Paganini T, Parolini S, Tabellini G, Mazza C, Savoldi G, Montin D, Martino S, Tovo P, Pessach IM, Massaad MJ, Ramesh N, Porta F, Plebani A, Notarangelo LD, Geha RS, Giliani S. A novel primary human immunodeficiency due to deficiency in the WASP-interacting protein WIP. J Exp Med. 2012 Jan 16; 209(1):29-34.
    View in: PubMed
  22. Oyoshi MK, Ramesh N, Geha RS. Vaccinia Ig ameliorates eczema vaccinatum in a murine model of atopic dermatitis. J Invest Dermatol. 2012 Apr; 132(4):1299-301.
    View in: PubMed
  23. Al-Herz W, Bousfiha A, Casanova JL, Chapel H, Conley ME, Cunningham-Rundles C, Etzioni A, Fischer A, Franco JL, Geha RS, Hammarström L, Nonoyama S, Notarangelo LD, Ochs HD, Puck JM, Roifman CM, Seger R, Tang ML. Primary immunodeficiency diseases: an update on the classification from the international union of immunological societies expert committee for primary immunodeficiency. Front Immunol. 2011; 2:54.
    View in: PubMed
  24. Oyoshi MK, Wang JY, Geha RS. Immunization with modified vaccinia virus Ankara prevents eczema vaccinatum in a murine model of atopic dermatitis. J Allergy Clin Immunol. 2011 Oct; 128(4):890-892.e3.
    View in: PubMed
  25. Ozcan E, Rauter I, Garibyan L, Dillon SR, Geha RS. Toll-like receptor 9, transmembrane activator and calcium-modulating cyclophilin ligand interactor, and CD40 synergize in causing B-cell activation. J Allergy Clin Immunol. 2011 Sep; 128(3):601-9.e1-4.
    View in: PubMed
  26. Oyoshi MK, Elkhal A, Scott JE, Wurbel MA, Hornick JL, Campbell JJ, Geha RS. Epicutaneous challenge of orally immunized mice redirects antigen-specific gut-homing T cells to the skin. J Clin Invest. 2011 Jun; 121(6):2210-20.
    View in: PubMed
  27. Fried AJ, Rauter I, Dillon SR, Jabara HH, Geha RS. Functional analysis of transmembrane activator and calcium-modulating cyclophilin ligand interactor (TACI) mutations associated with common variable immunodeficiency. J Allergy Clin Immunol. 2011 Jul; 128(1):226-228.e1.
    View in: PubMed
  28. Massaad MJ, Ramesh N, Le Bras S, Giliani S, Notarangelo LD, Al-Herz W, Notarangelo LD, Geha RS. A peptide derived from the Wiskott-Aldrich syndrome (WAS) protein-interacting protein (WIP) restores WAS protein level and actin cytoskeleton reorganization in lymphocytes from patients with WAS mutations that disrupt WIP binding. J Allergy Clin Immunol. 2011 Apr; 127(4):998-1005.e1-2.
    View in: PubMed
  29. Jabara HH, Angelini F, Brodeur SR, Geha RS. Ligation of CD46 to CD40 inhibits CD40 signaling in B cells. Int Immunol. 2011 Mar; 23(3):215-21.
    View in: PubMed
  30. McDonald DR, Massaad MJ, Johnston A, Keles S, Chatila T, Geha RS, Pai SY. Successful engraftment of donor marrow after allogeneic hematopoietic cell transplantation in autosomal-recessive hyper-IgE syndrome caused by dedicator of cytokinesis 8 deficiency. J Allergy Clin Immunol. 2010 Dec; 126(6):1304-5.e3.
    View in: PubMed
  31. Lee JJ, Jabara HH, Garibyan L, Rauter I, Sannikova T, Dillon SR, Bram R, Geha RS. The C104R mutant impairs the function of transmembrane activator and calcium modulator and cyclophilin ligand interactor (TACI) through haploinsufficiency. J Allergy Clin Immunol. 2010 Dec; 126(6):1234-41.e2.
    View in: PubMed
  32. Oyoshi MK, Larson RP, Ziegler SF, Geha RS. Mechanical injury polarizes skin dendritic cells to elicit a T(H)2 response by inducing cutaneous thymic stromal lymphopoietin expression. J Allergy Clin Immunol. 2010 Nov; 126(5):976-84, 984.e1-5.
    View in: PubMed
  33. Picard C, von Bernuth H, Ghandil P, Chrabieh M, Levy O, Arkwright PD, McDonald D, Geha RS, Takada H, Krause JC, Creech CB, Ku CL, Ehl S, Maródi L, Al-Muhsen S, Al-Hajjar S, Al-Ghonaium A, Day-Good NK, Holland SM, Gallin JI, Chapel H, Speert DP, Rodriguez-Gallego C, Colino E, Garty BZ, Roifman C, Hara T, Yoshikawa H, Nonoyama S, Domachowske J, Issekutz AC, Tang M, Smart J, Zitnik SE, Hoarau C, Kumararatne DS, Thrasher AJ, Davies EG, Bethune C, Sirvent N, de Ricaud D, Camcioglu Y, Vasconcelos J, Guedes M, Vitor AB, Rodrigo C, Almazán F, Méndez M, Aróstegui JI, Alsina L, Fortuny C, Reichenbach J, Verbsky JW, Bossuyt X, Doffinger R, Abel L, Puel A, Casanova JL. Clinical features and outcome of patients with IRAK-4 and MyD88 deficiency. Medicine (Baltimore). 2010 Nov; 89(6):403-25.
    View in: PubMed
  34. Koduru S, Kumar L, Massaad MJ, Ramesh N, Le Bras S, Ozcan E, Oyoshi MK, Kaku M, Fujiwara Y, Kremer L, King S, Fuhlbrigge R, Rodig S, Sage P, Carman C, Alcaide P, Luscinskas FW, Geha RS. Cdc42 interacting protein 4 (CIP4) is essential for integrin-dependent T-cell trafficking. Proc Natl Acad Sci U S A. 2010 Sep 14; 107(37):16252-6.
    View in: PubMed
  35. He R, Oyoshi MK, Wang JY, Hodge MR, Jin H, Geha RS. The prostaglandin D2 receptor CRTH2 is important for allergic skin inflammation after epicutaneous antigen challenge. J Allergy Clin Immunol. 2010 Oct; 126(4):784-90.
    View in: PubMed
  36. McDonald DR, Goldman F, Gomez-Duarte OD, Issekutz AC, Kumararatne DS, Doffinger R, Geha RS. Impaired T-cell receptor activation in IL-1 receptor-associated kinase-4-deficient patients. J Allergy Clin Immunol. 2010 Aug; 126(2):332-7, 337.e1-2.
    View in: PubMed
  37. Al-Herz W, Naguib KK, Notarangelo LD, Geha RS, Alwadaani A. Parental consanguinity and the risk of primary immunodeficiency disorders: report from the Kuwait National Primary Immunodeficiency Disorders Registry. Int Arch Allergy Immunol. 2011; 154(1):76-80.
    View in: PubMed
  38. Mooster JL, Cancrini C, Simonetti A, Rossi P, Di Matteo G, Romiti ML, Di Cesare S, Notarangelo L, Geha RS, McDonald DR. Immune deficiency caused by impaired expression of nuclear factor-kappaB essential modifier (NEMO) because of a mutation in the 5' untranslated region of the NEMO gene. J Allergy Clin Immunol. 2010 Jul; 126(1):127-32.e7.
    View in: PubMed
  39. He R, Geha RS. Thymic stromal lymphopoietin. Ann N Y Acad Sci. 2010 Jan; 1183:13-24.
    View in: PubMed
  40. Notarangelo LD, Fischer A, Geha RS, Casanova JL, Chapel H, Conley ME, Cunningham-Rundles C, Etzioni A, Hammartröm L, Nonoyama S, Ochs HD, Puck J, Roifman C, Seger R, Wedgwood J. Primary immunodeficiencies: 2009 update. J Allergy Clin Immunol. 2009 Dec; 124(6):1161-78.
    View in: PubMed
  41. He R, Kim HY, Yoon J, Oyoshi MK, MacGinnitie A, Goya S, Freyschmidt EJ, Bryce P, McKenzie AN, Umetsu DT, Oettgen HC, Geha RS. Exaggerated IL-17 response to epicutaneous sensitization mediates airway inflammation in the absence of IL-4 and IL-13. J Allergy Clin Immunol. 2009 Oct; 124(4):761-70.e1.
    View in: PubMed
  42. Falet H, Marchetti MP, Hoffmeister KM, Massaad MJ, Geha RS, Hartwig JH. Platelet-associated IgAs and impaired GPVI responses in platelets lacking WIP. Blood. 2009 Nov 19; 114(21):4729-37.
    View in: PubMed
  43. Oyoshi MK, Elkhal A, Kumar L, Scott JE, Koduru S, He R, Leung DY, Howell MD, Oettgen HC, Murphy GF, Geha RS. Vaccinia virus inoculation in sites of allergic skin inflammation elicits a vigorous cutaneous IL-17 response. Proc Natl Acad Sci U S A. 2009 Sep 1; 106(35):14954-9.
    View in: PubMed
  44. Oyoshi MK, Murphy GF, Geha RS. Filaggrin-deficient mice exhibit TH17-dominated skin inflammation and permissiveness to epicutaneous sensitization with protein antigen. J Allergy Clin Immunol. 2009 Sep; 124(3):485-93, 493.e1.
    View in: PubMed
  45. Lee JJ, Rauter I, Garibyan L, Ozcan E, Sannikova T, Dillon SR, Cruz AC, Siegel RM, Bram R, Jabara H, Geha RS. The murine equivalent of the A181E TACI mutation associated with common variable immunodeficiency severely impairs B-cell function. Blood. 2009 Sep 10; 114(11):2254-62.
    View in: PubMed
  46. Ozcan E, Garibyan L, Lee JJ, Bram RJ, Lam KP, Geha RS. Transmembrane activator, calcium modulator, and cyclophilin ligand interactor drives plasma cell differentiation in LPS-activated B cells. J Allergy Clin Immunol. 2009 Jun; 123(6):1277-86.e5.
    View in: PubMed
  47. Bonilla FA, Geha RS. Common variable immunodeficiency. Pediatr Res. 2009 May; 65(5 Pt 2):13R-19R.
    View in: PubMed
  48. Le Bras S, Massaad M, Koduru S, Kumar L, Oyoshi MK, Hartwig J, Geha RS. WIP is critical for T cell responsiveness to IL-2. Proc Natl Acad Sci U S A. 2009 May 5; 106(18):7519-24.
    View in: PubMed
  49. Jin H, Kumar L, Mathias C, Zurakowski D, Oettgen H, Gorelik L, Geha R. Toll-like receptor 2 is important for the T(H)1 response to cutaneous sensitization. J Allergy Clin Immunol. 2009 Apr; 123(4):875-82.e1.
    View in: PubMed
  50. Jabara HH, Weng Y, Sannikova T, Geha RS. TRAF2 and TRAF3 independently mediate Ig class switching driven by CD40. Int Immunol. 2009 Apr; 21(4):477-88.
    View in: PubMed
  51. Oyoshi MK, He R, Kumar L, Yoon J, Geha RS. Cellular and molecular mechanisms in atopic dermatitis. Adv Immunol. 2009; 102:135-226.
    View in: PubMed
  52. Jin H, He R, Oyoshi M, Geha RS. Animal models of atopic dermatitis. J Invest Dermatol. 2009 Jan; 129(1):31-40.
    View in: PubMed
  53. Ramesh N, Geha R. Recent advances in the biology of WASP and WIP. Immunol Res. 2009; 44(1-3):99-111.
    View in: PubMed
  54. Jin H, Oyoshi MK, Le Y, Bianchi T, Koduru S, Mathias CB, Kumar L, Le Bras S, Young D, Collins M, Grusby MJ, Wenzel J, Bieber T, Boes M, Silberstein LE, Oettgen HC, Geha RS. IL-21R is essential for epicutaneous sensitization and allergic skin inflammation in humans and mice. J Clin Invest. 2009 Jan; 119(1):47-60.
    View in: PubMed
  55. Lee JJ, Ozcan E, Rauter I, Geha RS. Transmembrane activator and calcium-modulator and cyclophilin ligand interactor mutations in common variable immunodeficiency. Curr Opin Allergy Clin Immunol. 2008 Dec; 8(6):520-6.
    View in: PubMed
  56. Ozcan E, Notarangelo LD, Geha RS. Primary immune deficiencies with aberrant IgE production. J Allergy Clin Immunol. 2008 Dec; 122(6):1054-62; quiz 1063-4.
    View in: PubMed
  57. Pai SY, Levy O, Jabara HH, Glickman JN, Stoler-Barak L, Sachs J, Nurko S, Orange JS, Geha RS. Allogeneic transplantation successfully corrects immune defects, but not susceptibility to colitis, in a patient with nuclear factor-kappaB essential modulator deficiency. J Allergy Clin Immunol. 2008 Dec; 122(6):1113-1118.e1.
    View in: PubMed
  58. Borzutzky A, Schneider LC, Geha RS. A girl with severe hand swelling and abdominal cramps. Clin Chem. 2008 Oct; 54(10):1733-6; discussion 1736-7.
    View in: PubMed
  59. He R, Oyoshi MK, Garibyan L, Kumar L, Ziegler SF, Geha RS. TSLP acts on infiltrating effector T cells to drive allergic skin inflammation. Proc Natl Acad Sci U S A. 2008 Aug 19; 105(33):11875-80.
    View in: PubMed
  60. Benson MJ, Dillon SR, Castigli E, Geha RS, Xu S, Lam KP, Noelle RJ. Cutting edge: the dependence of plasma cells and independence of memory B cells on BAFF and APRIL. J Immunol. 2008 Mar 15; 180(6):3655-9.
    View in: PubMed
  61. Shinohara M, Koga T, Okamoto K, Sakaguchi S, Arai K, Yasuda H, Takai T, Kodama T, Morio T, Geha RS, Kitamura D, Kurosaki T, Ellmeier W, Takayanagi H. Tyrosine kinases Btk and Tec regulate osteoclast differentiation by linking RANK and ITAM signals. Cell. 2008 Mar 7; 132(5):794-806.
    View in: PubMed
  62. Hidano S, Sasanuma H, Ohshima K, Seino K, Kumar L, Hayashi K, Hikida M, Kurosaki T, Taniguchi M, Geha RS, Kitamura D, Goitsuka R. Distinct regulatory functions of SLP-76 and MIST in NK cell cytotoxicity and IFN-gamma production. Int Immunol. 2008 Mar; 20(3):345-52.
    View in: PubMed
  63. McDonald DR, Mooster JL, Reddy M, Bawle E, Secord E, Geha RS. Heterozygous N-terminal deletion of IkappaBalpha results in functional nuclear factor kappaB haploinsufficiency, ectodermal dysplasia, and immune deficiency. J Allergy Clin Immunol. 2007 Oct; 120(4):900-7.
    View in: PubMed
  64. Geha RS, Notarangelo LD, Casanova JL, Chapel H, Conley ME, Fischer A, Hammarström L, Nonoyama S, Ochs HD, Puck JM, Roifman C, Seger R, Wedgwood J. Primary immunodeficiency diseases: an update from the International Union of Immunological Societies Primary Immunodeficiency Diseases Classification Committee. J Allergy Clin Immunol. 2007 Oct; 120(4):776-94.
    View in: PubMed
  65. Shearer WT, Cunningham-Rundles C, Ballow M, Ochs HD, Geha RS. Images in immunodeficiency. J Allergy Clin Immunol. 2007 Oct; 120(4):982-4.
    View in: PubMed
  66. Jabara HH, Chaudhuri J, Dutt S, Dedeoglu F, Weng Y, Murphy MM, Franco S, Alt FW, Manis J, Geha RS. B-cell receptor cross-linking delays activation-induced cytidine deaminase induction and inhibits class-switch recombination to IgE. J Allergy Clin Immunol. 2008 Jan; 121(1):191-196.e2.
    View in: PubMed
  67. Scott JE, ElKhal A, Freyschmidt EJ, MacArthur DH, McDonald D, Howell MD, Leung DY, Laouar A, Manjunath N, Bianchi T, Boes M, Oettgen HC, Geha RS. Impaired immune response to vaccinia virus inoculated at the site of cutaneous allergic inflammation. J Allergy Clin Immunol. 2007 Dec; 120(6):1382-8.
    View in: PubMed
  68. He R, Oyoshi MK, Jin H, Geha RS. Epicutaneous antigen exposure induces a Th17 response that drives airway inflammation after inhalation challenge. Proc Natl Acad Sci U S A. 2007 Oct 2; 104(40):15817-22.
    View in: PubMed
  69. Castigli E, Wilson SA, Elkhal A, Ozcan E, Garibyan L, Geha RS. Transmembrane activator and calcium modulator and cyclophilin ligand interactor enhances CD40-driven plasma cell differentiation. J Allergy Clin Immunol. 2007 Oct; 120(4):885-91.
    View in: PubMed
  70. Carman CV, Sage PT, Sciuto TE, de la Fuente MA, Geha RS, Ochs HD, Dvorak HF, Dvorak AM, Springer TA. Transcellular diapedesis is initiated by invasive podosomes. Immunity. 2007 Jun; 26(6):784-97.
    View in: PubMed
  71. Garibyan L, Lobito AA, Siegel RM, Call ME, Wucherpfennig KW, Geha RS. Dominant-negative effect of the heterozygous C104R TACI mutation in common variable immunodeficiency (CVID). J Clin Invest. 2007 Jun; 117(6):1550-7.
    View in: PubMed
  72. de la Fuente MA, Sasahara Y, Calamito M, Antón IM, Elkhal A, Gallego MD, Suresh K, Siminovitch K, Ochs HD, Anderson KC, Rosen FS, Geha RS, Ramesh N. WIP is a chaperone for Wiskott-Aldrich syndrome protein (WASP). Proc Natl Acad Sci U S A. 2007 Jan 16; 104(3):926-31.
    View in: PubMed
  73. Castigli E, Geha RS. TACI, isotype switching, CVID and IgAD. Immunol Res. 2007; 38(1-3):102-11.
    View in: PubMed
  74. Koduru S, Massaad M, Wilbur C, Kumar L, Geha R, Ramesh N. A novel anti-WIP monoclonal antibody detects an isoform of WIP that lacks the WASP binding domain. Biochem Biophys Res Commun. 2007 Feb 23; 353(4):875-81.
    View in: PubMed
  75. McDonald DR, Brown D, Bonilla FA, Geha RS. Interleukin receptor-associated kinase-4 deficiency impairs Toll-like receptor-dependent innate antiviral immune responses. J Allergy Clin Immunol. 2006 Dec; 118(6):1357-62.
    View in: PubMed
  76. Elkhal A, Pichavant M, He R, Scott J, Meyer E, Goya S, Geha RS, Umetsu DT. CD1d restricted natural killer T cells are not required for allergic skin inflammation. J Allergy Clin Immunol. 2006 Dec; 118(6):1363-8.
    View in: PubMed
  77. Rachid R, Castigli E, Geha RS, Bonilla FA. TACI mutation in common variable immunodeficiency and IgA deficiency. Curr Allergy Asthma Rep. 2006 Sep; 6(5):357-62.
    View in: PubMed
  78. de la Fuente MA, Kumar L, Lu B, Geha RS. 3BP2 deficiency impairs the response of B cells, but not T cells, to antigen receptor ligation. Mol Cell Biol. 2006 Jul; 26(14):5214-25.
    View in: PubMed
  79. Le Bras S, Geha RS. IPEX and the role of Foxp3 in the development and function of human Tregs. J Clin Invest. 2006 Jun; 116(6):1473-5.
    View in: PubMed
  80. Bryce PJ, Mathias CB, Harrison KL, Watanabe T, Geha RS, Oettgen HC. The H1 histamine receptor regulates allergic lung responses. J Clin Invest. 2006 Jun; 116(6):1624-32.
    View in: PubMed
  81. Castigli E, Geha RS. Molecular basis of common variable immunodeficiency. J Allergy Clin Immunol. 2006 Apr; 117(4):740-6; quiz 747.
    View in: PubMed
  82. Du W, Kumaki S, Uchiyama T, Yachie A, Yeng Looi C, Kawai S, Minegishi M, Ramesh N, Geha RS, Sasahara Y, Tsuchiya S. A second-site mutation in the initiation codon of WAS (WASP) results in expansion of subsets of lymphocytes in an Wiskott-Aldrich syndrome patient. Hum Mutat. 2006 Apr; 27(4):370-5.
    View in: PubMed
  83. Notarangelo L, Casanova JL, Conley ME, Chapel H, Fischer A, Puck J, Roifman C, Seger R, Geha RS. Primary immunodeficiency diseases: an update from the International Union of Immunological Societies Primary Immunodeficiency Diseases Classification Committee Meeting in Budapest, 2005. J Allergy Clin Immunol. 2006 Apr; 117(4):883-96.
    View in: PubMed
  84. Yalcindag A, He R, Laouini D, Alenius H, Carroll M, Oettgen HC, Geha RS. The complement component C3 plays a critical role in both Th1 and Th2 responses to antigen. J Allergy Clin Immunol. 2006 Jun; 117(6):1455-61.
    View in: PubMed
  85. Bonilla FA, Geha RS. 2. Update on primary immunodeficiency diseases. J Allergy Clin Immunol. 2006 Feb; 117(2 Suppl Mini-Primer):S435-41.
    View in: PubMed
  86. McDonald DR, Janssen R, Geha R. Lessons learned from molecular defects in nuclear factor kappaB dependent signaling. Microbes Infect. 2006 Apr; 8(4):1151-6.
    View in: PubMed
  87. Kumar L, Feske S, Rao A, Geha RS. A 10-aa-long sequence in SLP-76 upstream of the Gads binding site is essential for T cell development and function. Proc Natl Acad Sci U S A. 2005 Dec 27; 102(52):19063-8.
    View in: PubMed
  88. Cianferoni A, Massaad M, Feske S, de la Fuente MA, Gallego L, Ramesh N, Geha RS. Defective nuclear translocation of nuclear factor of activated T cells and extracellular signal-regulated kinase underlies deficient IL-2 gene expression in Wiskott-Aldrich syndrome. J Allergy Clin Immunol. 2005 Dec; 116(6):1364-71.
    View in: PubMed
  89. Geha RS. Charles A. Janeway and Fred S. Rosen: the discovery of gamma globulin therapy and primary immunodeficiency diseases at Boston Children's Hospital. J Allergy Clin Immunol. 2005 Oct; 116(4):937-40.
    View in: PubMed
  90. Gallego MD, de la Fuente MA, Anton IM, Snapper S, Fuhlbrigge R, Geha RS. WIP and WASP play complementary roles in T cell homing and chemotaxis to SDF-1alpha. Int Immunol. 2006 Feb; 18(2):221-32.
    View in: PubMed
  91. Bonilla FA, Geha RS. Are you immunodeficient? J Allergy Clin Immunol. 2005 Aug; 116(2):423-5.
    View in: PubMed
  92. Laouini D, Elkhal A, Yalcindag A, Kawamoto S, Oettgen H, Geha RS. COX-2 inhibition enhances the TH2 immune response to epicutaneous sensitization. J Allergy Clin Immunol. 2005 Aug; 116(2):390-6.
    View in: PubMed
  93. Castigli E, Wilson SA, Garibyan L, Rachid R, Bonilla F, Schneider L, Geha RS. TACI is mutant in common variable immunodeficiency and IgA deficiency. Nat Genet. 2005 Aug; 37(8):829-34.
    View in: PubMed
  94. Nishida K, Yamasaki S, Ito Y, Kabu K, Hattori K, Tezuka T, Nishizumi H, Kitamura D, Goitsuka R, Geha RS, Yamamoto T, Yagi T, Hirano T. Fc{epsilon}RI-mediated mast cell degranulation requires calcium-independent microtubule-dependent translocation of granules to the plasma membrane. J Cell Biol. 2005 Jul 4; 170(1):115-26.
    View in: PubMed
  95. Geha RS. Role of APRIL in the mucosal Iga antibody response. J Pediatr Gastroenterol Nutr. 2005 Apr; 40 Suppl 1:S27.
    View in: PubMed
  96. Jabara HH, Geha RS. Jun N-terminal kinase is essential for CD40-mediated IgE class switching in B cells. J Allergy Clin Immunol. 2005 Apr; 115(4):856-63.
    View in: PubMed
  97. Orange JS, Levy O, Geha RS. Human disease resulting from gene mutations that interfere with appropriate nuclear factor-kappaB activation. Immunol Rev. 2005 Feb; 203:21-37.
    View in: PubMed
  98. Castigli E, Wilson SA, Scott S, Dedeoglu F, Xu S, Lam KP, Bram RJ, Jabara H, Geha RS. TACI and BAFF-R mediate isotype switching in B cells. J Exp Med. 2005 Jan 3; 201(1):35-9.
    View in: PubMed
  99. Dai YS, Liang MG, Gellis SE, Bonilla FA, Schneider LC, Geha RS, Orange JS. Characteristics of mycobacterial infection in patients with immunodeficiency and nuclear factor-kappaB essential modulator mutation, with or without ectodermal dysplasia. J Am Acad Dermatol. 2004 Nov; 51(5):718-22.
    View in: PubMed
  100. Notarangelo L, Casanova JL, Fischer A, Puck J, Rosen F, Seger R, Geha R. Primary immunodeficiency diseases: an update. J Allergy Clin Immunol. 2004 Sep; 114(3):677-87.
    View in: PubMed
  101. Orange JS, Levy O, Brodeur SR, Krzewski K, Roy RM, Niemela JE, Fleisher TA, Bonilla FA, Geha RS. Human nuclear factor kappa B essential modulator mutation can result in immunodeficiency without ectodermal dysplasia. J Allergy Clin Immunol. 2004 Sep; 114(3):650-6.
    View in: PubMed
  102. Kawamoto S, Yalcindag A, Laouini D, Brodeur S, Bryce P, Lu B, Humbles AA, Oettgen H, Gerard C, Geha RS. The anaphylatoxin C3a downregulates the Th2 response to epicutaneously introduced antigen. J Clin Invest. 2004 Aug; 114(3):399-407.
    View in: PubMed
  103. Vivarelli MS, McDonald D, Miller M, Cusson N, Kelliher M, Geha RS. RIP links TLR4 to Akt and is essential for cell survival in response to LPS stimulation. J Exp Med. 2004 Aug 2; 200(3):399-404.
    View in: PubMed
  104. Martinez-Quiles N, Ho HY, Kirschner MW, Ramesh N, Geha RS. Erk/Src phosphorylation of cortactin acts as a switch on-switch off mechanism that controls its ability to activate N-WASP. Mol Cell Biol. 2004 Jun; 24(12):5269-80.
    View in: PubMed
  105. Orange JS, Jain A, Ballas ZK, Schneider LC, Geha RS, Bonilla FA. The presentation and natural history of immunodeficiency caused by nuclear factor kappaB essential modulator mutation. J Allergy Clin Immunol. 2004 Apr; 113(4):725-33.
    View in: PubMed
  106. Dedeoglu F, Horwitz B, Chaudhuri J, Alt FW, Geha RS. Induction of activation-induced cytidine deaminase gene expression by IL-4 and CD40 ligation is dependent on STAT6 and NFkappaB. Int Immunol. 2004 Mar; 16(3):395-404.
    View in: PubMed
  107. Castigli E, Scott S, Dedeoglu F, Bryce P, Jabara H, Bhan AK, Mizoguchi E, Geha RS. Impaired IgA class switching in APRIL-deficient mice. Proc Natl Acad Sci U S A. 2004 Mar 16; 101(11):3903-8.
    View in: PubMed
  108. Kettner A, Kumar L, Antón IM, Sasahara Y, de la Fuente M, Pivniouk VI, Falet H, Hartwig JH, Geha RS. WIP regulates signaling via the high affinity receptor for immunoglobulin E in mast cells. J Exp Med. 2004 Feb 2; 199(3):357-68.
    View in: PubMed
  109. Geha RS. Allergy and hypersensitivity. Nature versus nurture in allergy and hypersensitivity. Curr Opin Immunol. 2003 Dec; 15(6):603-8.
    View in: PubMed
  110. Pivniouk VI, Snapper SB, Kettner A, Alenius H, Laouini D, Falet H, Hartwig J, Alt FW, Geha RS. Impaired signaling via the high-affinity IgE receptor in Wiskott-Aldrich syndrome protein-deficient mast cells. Int Immunol. 2003 Dec; 15(12):1431-40.
    View in: PubMed
  111. Orange JS, Harris KE, Andzelm MM, Valter MM, Geha RS, Strominger JL. The mature activating natural killer cell immunologic synapse is formed in distinct stages. Proc Natl Acad Sci U S A. 2003 Nov 25; 100(24):14151-6.
    View in: PubMed
  112. Winkelstein JA, Marino MC, Ochs H, Fuleihan R, Scholl PR, Geha R, Stiehm ER, Conley ME. The X-linked hyper-IgM syndrome: clinical and immunologic features of 79 patients. Medicine (Baltimore). 2003 Nov; 82(6):373-84.
    View in: PubMed
  113. Laouini D, Kawamoto S, Yalcindag A, Bryce P, Mizoguchi E, Oettgen H, Geha RS. Epicutaneous sensitization with superantigen induces allergic skin inflammation. J Allergy Clin Immunol. 2003 Nov; 112(5):981-7.
    View in: PubMed
  114. Blaeser F, Bryce PJ, Ho N, Raman V, Dedeoglu F, Donaldson DD, Geha RS, Oettgen HC, Chatila TA. Targeted inactivation of the IL-4 receptor alpha chain I4R motif promotes allergic airway inflammation. J Exp Med. 2003 Oct 20; 198(8):1189-200.
    View in: PubMed
  115. Orange JS, Geha RS. Finding NEMO: genetic disorders of NF-[kappa]B activation. J Clin Invest. 2003 Oct; 112(7):983-5.
    View in: PubMed
  116. Laouini D, Alenius H, Bryce P, Oettgen H, Tsitsikov E, Geha RS. IL-10 is critical for Th2 responses in a murine model of allergic dermatitis. J Clin Invest. 2003 Oct; 112(7):1058-66.
    View in: PubMed
  117. Levy O, Orange JS, Hibberd P, Steinberg S, LaRussa P, Weinberg A, Wilson SB, Shaulov A, Fleisher G, Geha RS, Bonilla FA, Exley M. Disseminated varicella infection due to the vaccine strain of varicella-zoster virus, in a patient with a novel deficiency in natural killer T cells. J Infect Dis. 2003 Oct 1; 188(7):948-53.
    View in: PubMed
  118. Geha RS, Jabara HH, Brodeur SR. The regulation of immunoglobulin E class-switch recombination. Nat Rev Immunol. 2003 Sep; 3(9):721-32.
    View in: PubMed
  119. Orange JS, Geha RS, Bonilla FA. Acute chylothorax in children: selective retention of memory T cells and natural killer cells. J Pediatr. 2003 Aug; 143(2):243-9.
    View in: PubMed
  120. Yan C, Martinez-Quiles N, Eden S, Shibata T, Takeshima F, Shinkura R, Fujiwara Y, Bronson R, Snapper SB, Kirschner MW, Geha R, Rosen FS, Alt FW. WAVE2 deficiency reveals distinct roles in embryogenesis and Rac-mediated actin-based motility. EMBO J. 2003 Jul 15; 22(14):3602-12.
    View in: PubMed
  121. Bryce PJ, Geha R, Oettgen HC. Desloratadine inhibits allergen-induced airway inflammation and bronchial hyperresponsiveness and alters T-cell responses in murine models of asthma. J Allergy Clin Immunol. 2003 Jul; 112(1):149-58.
    View in: PubMed
  122. Brodeur SR, Angelini F, Bacharier LB, Blom AM, Mizoguchi E, Fujiwara H, Plebani A, Notarangelo LD, Dahlback B, Tsitsikov E, Geha RS. C4b-binding protein (C4BP) activates B cells through the CD40 receptor. Immunity. 2003 Jun; 18(6):837-48.
    View in: PubMed
  123. Antón IM, Saville SP, Byrne MJ, Curcio C, Ramesh N, Hartwig JH, Geha RS. WIP participates in actin reorganization and ruffle formation induced by PDGF. J Cell Sci. 2003 Jun 15; 116(Pt 12):2443-51.
    View in: PubMed
  124. Chapel H, Geha R, Rosen F. Primary immunodeficiency diseases: an update. Clin Exp Immunol. 2003 Apr; 132(1):9-15.
    View in: PubMed
  125. Binstadt BA, Geha RS, Bonilla FA. IgG Fc receptor polymorphisms in human disease: implications for intravenous immunoglobulin therapy. J Allergy Clin Immunol. 2003 Apr; 111(4):697-703.
    View in: PubMed
  126. Kettner A, Pivniouk V, Kumar L, Falet H, Lee JS, Mulligan R, Geha RS. Structural requirements of SLP-76 in signaling via the high-affinity immunoglobulin E receptor (Fc epsilon RI) in mast cells. Mol Cell Biol. 2003 Apr; 23(7):2395-406.
    View in: PubMed
  127. Bonilla FA, Geha RS. 12. Primary immunodeficiency diseases. J Allergy Clin Immunol. 2003 Feb; 111(2 Suppl):S571-81.
    View in: PubMed
  128. Sasahara Y, Rachid R, Byrne MJ, de la Fuente MA, Abraham RT, Ramesh N, Geha RS. Mechanism of recruitment of WASP to the immunological synapse and of its activation following TCR ligation. Mol Cell. 2002 Dec; 10(6):1269-81.
    View in: PubMed
  129. Jabara H, Laouini D, Tsitsikov E, Mizoguchi E, Bhan A, Castigli E, Dedeoglu F, Pivniouk V, Brodeur S, Geha R. The binding site for TRAF2 and TRAF3 but not for TRAF6 is essential for CD40-mediated immunoglobulin class switching. Immunity. 2002 Sep; 17(3):265-76.
    View in: PubMed
  130. MacGinnitie AJ, Geha R. X-linked lymphoproliferative disease: genetic lesions and clinical consequences. Curr Allergy Asthma Rep. 2002 Sep; 2(5):361-7.
    View in: PubMed
  131. Orange JS, Ramesh N, Remold-O'Donnell E, Sasahara Y, Koopman L, Byrne M, Bonilla FA, Rosen FS, Geha RS, Strominger JL. Wiskott-Aldrich syndrome protein is required for NK cell cytotoxicity and colocalizes with actin to NK cell-activating immunologic synapses. Proc Natl Acad Sci U S A. 2002 Aug 20; 99(17):11351-6.
    View in: PubMed
  132. Arima K, Umeshita-Suyama R, Sakata Y, Akaiwa M, Mao XQ, Enomoto T, Dake Y, Shimazu S, Yamashita T, Sugawara N, Brodeur S, Geha R, Puri RK, Sayegh MH, Adra CN, Hamasaki N, Hopkin JM, Shirakawa T, Izuhara K. Upregulation of IL-13 concentration in vivo by the IL13 variant associated with bronchial asthma. J Allergy Clin Immunol. 2002 Jun; 109(6):980-7.
    View in: PubMed
  133. Orange JS, Brodeur SR, Jain A, Bonilla FA, Schneider LC, Kretschmer R, Nurko S, Rasmussen WL, Köhler JR, Gellis SE, Ferguson BM, Strominger JL, Zonana J, Ramesh N, Ballas ZK, Geha RS. Deficient natural killer cell cytotoxicity in patients with IKK-gamma/NEMO mutations. J Clin Invest. 2002 Jun; 109(11):1501-9.
    View in: PubMed
  134. Butchko HH, Stargel WW, Comer CP, Mayhew DA, Benninger C, Blackburn GL, de Sonneville LM, Geha RS, Hertelendy Z, Koestner A, Leon AS, Liepa GU, McMartin KE, Mendenhall CL, Munro IC, Novotny EJ, Renwick AG, Schiffman SS, Schomer DL, Shaywitz BA, Spiers PA, Tephly TR, Thomas JA, Trefz FK. Aspartame: review of safety. Regul Toxicol Pharmacol. 2002 Apr; 35(2 Pt 2):S1-93.
    View in: PubMed
  135. Ma W, Bryce PJ, Humbles AA, Laouini D, Yalcindag A, Alenius H, Friend DS, Oettgen HC, Gerard C, Geha RS. CCR3 is essential for skin eosinophilia and airway hyperresponsiveness in a murine model of allergic skin inflammation. J Clin Invest. 2002 Mar; 109(5):621-8.
    View in: PubMed
  136. Antón IM, de la Fuente MA, Sims TN, Freeman S, Ramesh N, Hartwig JH, Dustin ML, Geha RS. WIP deficiency reveals a differential role for WIP and the actin cytoskeleton in T and B cell activation. Immunity. 2002 Feb; 16(2):193-204.
    View in: PubMed
  137. Kumar L, Pivniouk V, de la Fuente MA, Laouini D, Geha RS. Differential role of SLP-76 domains in T cell development and function. Proc Natl Acad Sci U S A. 2002 Jan 22; 99(2):884-9.
    View in: PubMed
  138. Alenius H, Laouini D, Woodward A, Mizoguchi E, Bhan AK, Castigli E, Oettgen HC, Geha RS. Mast cells regulate IFN-gamma expression in the skin and circulating IgE levels in allergen-induced skin inflammation. J Allergy Clin Immunol. 2002 Jan; 109(1):106-13.
    View in: PubMed
  139. Celestin J, Rotschke O, Falk K, Ramesh N, Jabara H, Strominger J, Geha RS. IL-3 induces B7.2 (CD86) expression and costimulatory activity in human eosinophils. J Immunol. 2001 Dec 1; 167(11):6097-104.
    View in: PubMed
  140. Tsitsikov EN, Laouini D, Dunn IF, Sannikova TY, Davidson L, Alt FW, Geha RS. TRAF1 is a negative regulator of TNF signaling. enhanced TNF signaling in TRAF1-deficient mice. Immunity. 2001 Oct; 15(4):647-57.
    View in: PubMed
  141. Snapper SB, Takeshima F, Antón I, Liu CH, Thomas SM, Nguyen D, Dudley D, Fraser H, Purich D, Lopez-Ilasaca M, Klein C, Davidson L, Bronson R, Mulligan RC, Southwick F, Geha R, Goldberg MB, Rosen FS, Hartwig JH, Alt FW. N-WASP deficiency reveals distinct pathways for cell surface projections and microbial actin-based motility. Nat Cell Biol. 2001 Oct; 3(10):897-904.
    View in: PubMed
  142. Martinez-Quiles N, Rohatgi R, Antón IM, Medina M, Saville SP, Miki H, Yamaguchi H, Takenawa T, Hartwig JH, Geha RS, Ramesh N. WIP regulates N-WASP-mediated actin polymerization and filopodium formation. Nat Cell Biol. 2001 May; 3(5):484-91.
    View in: PubMed
  143. Geha RS, Meltzer EO. Desloratadine: A new, nonsedating, oral antihistamine. J Allergy Clin Immunol. 2001 Apr; 107(4):751-62.
    View in: PubMed
  144. Oettgen HC, Geha RS. IgE regulation and roles in asthma pathogenesis. J Allergy Clin Immunol. 2001 Mar; 107(3):429-40.
    View in: PubMed
  145. Woodward AL, Spergel JM, Alenius H, Mizoguchi E, Bhan AK, Castigli E, Brodeur SR, Oettgen HC, Geha RS. An obligate role for T-cell receptor alphabeta+ T cells but not T-cell receptor gammadelta+ T cells, B cells, or CD40/CD40L interactions in a mouse model of atopic dermatitis. J Allergy Clin Immunol. 2001 Feb; 107(2):359-66.
    View in: PubMed
  146. Jabara HH, Brodeur SR, Geha RS. Glucocorticoids upregulate CD40 ligand expression and induce CD40L-dependent immunoglobulin isotype switching. J Clin Invest. 2001 Feb; 107(3):371-8.
    View in: PubMed
  147. Geha RS. Allergy, a disease of the internal and external environments Curr Opin Immunol. 2000 Dec; 12(6):615-7.
    View in: PubMed
  148. Falet H, Barkalow KL, Pivniouk VI, Barnes MJ, Geha RS, Hartwig JH. Roles of SLP-76, phosphoinositide 3-kinase, and gelsolin in the platelet shape changes initiated by the collagen receptor GPVI/FcR gamma-chain complex. Blood. 2000 Dec 1; 96(12):3786-92.
    View in: PubMed
  149. Dunn IF, Sannikova TY, Geha RS, Tsitsikov EN. Identification and characterization of two CD40-inducible enhancers in the mouse TRAF1 gene locus. Mol Immunol. 2000 Nov; 37(16):961-73.
    View in: PubMed
  150. Geha RS, Beiser A, Ren C, Patterson R, Greenberger PA, Grammer LC, Ditto AM, Harris KE, Shaughnessy MA, Yarnold PR, Corren J, Saxon A. Multicenter, double-blind, placebo-controlled, multiple-challenge evaluation of reported reactions to monosodium glutamate. J Allergy Clin Immunol. 2000 Nov; 106(5):973-80.
    View in: PubMed
  151. Mehlhop PD, van de Rijn M, Brewer JP, Kisselgof AB, Geha RS, Oettgen HC, Martin TR. CD40L, but not CD40, is required for allergen-induced bronchial hyperresponsiveness in mice. Am J Respir Cell Mol Biol. 2000 Nov; 23(5):646-51.
    View in: PubMed
  152. Geha RS, Beiser A, Ren C, Patterson R, Greenberger PA, Grammer LC, Ditto AM, Harris KE, Shaughnessy MA, Yarnold PR, Corren J, Saxon A. Review of alleged reaction to monosodium glutamate and outcome of a multicenter double-blind placebo-controlled study. J Nutr. 2000 Apr; 130(4S Suppl):1058S-62S.
    View in: PubMed
  153. Pivniouk VI, Geha RS. The role of SLP-76 and LAT in lymphocyte development. Curr Opin Immunol. 2000 Apr; 12(2):173-8.
    View in: PubMed
  154. Bonilla FA, Fujita RM, Pivniouk VI, Chan AC, Geha RS. Adapter proteins SLP-76 and BLNK both are expressed by murine macrophages and are linked to signaling via Fcgamma receptors I and II/III. Proc Natl Acad Sci U S A. 2000 Feb 15; 97(4):1725-30.
    View in: PubMed
  155. Bacharier LB, Geha RS. Molecular mechanisms of IgE regulation. J Allergy Clin Immunol. 2000 Feb; 105(2 Pt 2):S547-58.
    View in: PubMed
  156. Aifantis I, Pivniouk VI, Gärtner F, Feinberg J, Swat W, Alt FW, von Boehmer H, Geha RS. Allelic exclusion of the T cell receptor beta locus requires the SH2 domain-containing leukocyte protein (SLP)-76 adaptor protein. J Exp Med. 1999 Oct 18; 190(8):1093-102.
    View in: PubMed
  157. Oettgen HC, Geha RS. IgE in asthma and atopy: cellular and molecular connections. J Clin Invest. 1999 Oct; 104(7):829-35.
    View in: PubMed
  158. Morio T, Hanissian SH, Bacharier LB, Teraoka H, Nonoyama S, Seki M, Kondo J, Nakano H, Lee SK, Geha RS, Yata J. Ku in the cytoplasm associates with CD40 in human B cells and translocates into the nucleus following incubation with IL-4 and anti-CD40 mAb. Immunity. 1999 Sep; 11(3):339-48.
    View in: PubMed
  159. Vaduva G, Martinez-Quiles N, Anton IM, Martin NC, Geha RS, Hopper AK, Ramesh N. The human WASP-interacting protein, WIP, activates the cell polarity pathway in yeast. J Biol Chem. 1999 Jun 11; 274(24):17103-8.
    View in: PubMed
  160. Dunn IF, Geha RS, Tsitsikov EN. Structure of the murine TRAF1 gene. Mol Immunol. 1999 Jun; 36(9):611-7.
    View in: PubMed
  161. Pivniouk VI, Martin TR, Lu-Kuo JM, Katz HR, Oettgen HC, Geha RS. SLP-76 deficiency impairs signaling via the high-affinity IgE receptor in mast cells. J Clin Invest. 1999 Jun; 103(12):1737-43.
    View in: PubMed
  162. Förster E, Krenger W, Joergensen J, Hof R, Geha RS, Holländer GA. Contribution of CD40-CD154-mediated costimulation to an alloresponse in vivo. Transplantation. 1999 May 15; 67(9):1284-7.
    View in: PubMed
  163. Salmun LM, Barlan I, Wolf HM, Eibl M, Twarog FJ, Geha RS, Schneider LC. Effect of intravenous immunoglobulin on steroid consumption in patients with severe asthma: a double-blind, placebo-controlled, randomized trial. J Allergy Clin Immunol. 1999 May; 103(5 Pt 1):810-5.
    View in: PubMed
  164. Spergel JM, Mizoguchi E, Oettgen H, Bhan AK, Geha RS. Roles of TH1 and TH2 cytokines in a murine model of allergic dermatitis. J Clin Invest. 1999 Apr; 103(8):1103-11.
    View in: PubMed
  165. Bacharier LB, Geha RS. Regulation of IgE synthesis: the molecular basis and implications for clinical modulation. Allergy Asthma Proc. 1999 Jan-Feb; 20(1):1-8.
    View in: PubMed
  166. Ramesh N, Antón IM, Martínez-Quiles N, Geha RS. Waltzing with WASP. Trends Cell Biol. 1999 Jan; 9(1):15-9.
    View in: PubMed
  167. Tsytsykova AV, Tsitsikov EN, Wright DA, Futcher B, Geha RS. The mouse genome contains two expressed intronless retroposed pseudogenes for the sentrin/sumo-1/PIC1 conjugating enzyme Ubc9. Mol Immunol. 1998 Nov; 35(16):1057-67.
    View in: PubMed
  168. Sayos J, Wu C, Morra M, Wang N, Zhang X, Allen D, van Schaik S, Notarangelo L, Geha R, Roncarolo MG, Oettgen H, De Vries JE, Aversa G, Terhorst C. The X-linked lymphoproliferative-disease gene product SAP regulates signals induced through the co-receptor SLAM. Nature. 1998 Oct 1; 395(6701):462-9.
    View in: PubMed
  169. Jabara HH, Buckley RH, Roberts JL, Lefranc G, Loiselet J, Khalil G, Geha RS. Role of JAK3 in CD40-mediated signaling. Blood. 1998 Oct 1; 92(7):2435-40.
    View in: PubMed
  170. Antón IM, Lu W, Mayer BJ, Ramesh N, Geha RS. The Wiskott-Aldrich syndrome protein-interacting protein (WIP) binds to the adaptor protein Nck. J Biol Chem. 1998 Aug 14; 273(33):20992-5.
    View in: PubMed
  171. Pivniouk V, Tsitsikov E, Swinton P, Rathbun G, Alt FW, Geha RS. Impaired viability and profound block in thymocyte development in mice lacking the adaptor protein SLP-76. Cell. 1998 Jul 24; 94(2):229-38.
    View in: PubMed
  172. Dioun AF, Ewenstein BM, Geha RS, Schneider LC. IgE-mediated allergy and desensitization to factor IX in hemophilia B. J Allergy Clin Immunol. 1998 Jul; 102(1):113-7.
    View in: PubMed
  173. Spergel JM, Mizoguchi E, Brewer JP, Martin TR, Bhan AK, Geha RS. Epicutaneous sensitization with protein antigen induces localized allergic dermatitis and hyperresponsiveness to methacholine after single exposure to aerosolized antigen in mice. J Clin Invest. 1998 Apr 15; 101(8):1614-22.
    View in: PubMed
  174. Bacharier LB, Jabara H, Geha RS. Molecular mechanisms of immunoglobulin E regulation. Int Arch Allergy Immunol. 1998 Apr; 115(4):257-69.
    View in: PubMed
  175. Worm MM, Tsytsykova A, Geha RS. CD40 ligation and IL-4 use different mechanisms of transcriptional activation of the human lymphotoxin alpha promoter in B cells. Eur J Immunol. 1998 Mar; 28(3):901-6.
    View in: PubMed
  176. Ramesh N, Seki M, Notarangelo LD, Geha RS. The hyper-IgM (HIM) syndrome. Springer Semin Immunopathol. 1998; 19(4):383-99.
    View in: PubMed
  177. Ramesh N, Antón IM, Hartwig JH, Geha RS. WIP, a protein associated with wiskott-aldrich syndrome protein, induces actin polymerization and redistribution in lymphoid cells. Proc Natl Acad Sci U S A. 1997 Dec 23; 94(26):14671-6.
    View in: PubMed
  178. Bonilla FA, Kokron CM, Swinton P, Geha RS. Targeted gene disruption of murine CD7. Int Immunol. 1997 Dec; 9(12):1875-83.
    View in: PubMed
  179. Tsitsikov EN, Gutierrez-Ramos JC, Geha RS. Impaired CD19 expression and signaling, enhanced antibody response to type II T independent antigen and reduction of B-1 cells in CD81-deficient mice. Proc Natl Acad Sci U S A. 1997 Sep 30; 94(20):10844-9.
    View in: PubMed
  180. Fujiwara H, Hanissian SH, Tsytsykova A, Geha RS. Homodimerization of the human interleukin 4 receptor alpha chain induces Cepsilon germline transcripts in B cells in the absence of the interleukin 2 receptor gamma chain. Proc Natl Acad Sci U S A. 1997 May 27; 94(11):5866-71.
    View in: PubMed
  181. Hanissian SH, Geha RS. Jak3 is associated with CD40 and is critical for CD40 induction of gene expression in B cells. Immunity. 1997 Apr; 6(4):379-87.
    View in: PubMed
  182. Khan WN, Nilsson A, Mizoguchi E, Castigli E, Forsell J, Bhan AK, Geha R, Sideras P, Alt FW. Impaired B cell maturation in mice lacking Bruton's tyrosine kinase (Btk) and CD40. Int Immunol. 1997 Mar; 9(3):395-405.
    View in: PubMed
  183. Kokron CM, Bonilla FA, Oettgen HC, Ramesh N, Geha RS, Pandolfi F. Searching for genes involved in the pathogenesis of primary immunodeficiency diseases: lessons from mouse knockouts. J Clin Immunol. 1997 Mar; 17(2):109-26.
    View in: PubMed
  184. Tsitsikov EN, Wright DA, Geha RS. CD30 induction of human immunodeficiency virus gene transcription is mediated by TRAF2. Proc Natl Acad Sci U S A. 1997 Feb 18; 94(4):1390-5.
    View in: PubMed
  185. Morio T, Chatila T, Geha RS. HIV glycoprotein gp120 inhibits TCR-CD3-mediated activation of fyn and lck. Int Immunol. 1997 Jan; 9(1):53-64.
    View in: PubMed
  186. Wright DA, Futcher B, Ghosh P, Geha RS. Association of human fas (CD95) with a ubiquitin-conjugating enzyme (UBC-FAP). J Biol Chem. 1996 Dec 6; 271(49):31037-43.
    View in: PubMed
  187. Gorlin JB, Vamvakas EC, Cooke E, Galacki D, Geha R, Humphreys D, Kent P. Large-volume leukapheresis in pediatric patients: processing more blood diminishes the apparent magnitude of intra-apheresis recruitment. Transfusion. 1996 Oct; 36(10):879-85.
    View in: PubMed
  188. Jabara HH, Geha RS. The superantigen toxic shock syndrome toxin-1 induces CD40 ligand expression and modulates IgE isotype switching. Int Immunol. 1996 Oct; 8(10):1503-10.
    View in: PubMed
  189. Holländer GA, Castigli E, Kulbacki R, Su M, Burakoff SJ, Gutierrez-Ramos JC, Geha RS. Induction of alloantigen-specific tolerance by B cells from CD40-deficient mice. Proc Natl Acad Sci U S A. 1996 May 14; 93(10):4994-8.
    View in: PubMed
  190. Loh RK, Jabara HH, Geha RS. Mechanisms of inhibition of IgE synthesis by nedocromil sodium: nedocromil sodium inhibits deletional switch recombination in human B cells. J Allergy Clin Immunol. 1996 May; 97(5):1141-50.
    View in: PubMed
  191. Castigli E, Young F, Carossino AM, Alt FW, Geha RS. CD40 expression and function in murine B cell ontogeny. Int Immunol. 1996 Mar; 8(3):405-411.
    View in: PubMed
  192. Jawahar S, Moody C, Chan M, Finberg R, Geha R, Chatila T. Natural Killer (NK) cell deficiency associated with an epitope-deficient Fc receptor type IIIA (CD16-II). Clin Exp Immunol. 1996 Mar; 103(3):408-13.
    View in: PubMed
  193. Tsytsykova AV, Tsitsikov EN, Geha RS. The CD40L promoter contains nuclear factor of activated T cells-binding motifs which require AP-1 binding for activation of transcription. J Biol Chem. 1996 Feb 16; 271(7):3763-70.
    View in: PubMed
  194. Morio T, Hanissian S, Geha RS. Characterization of a 23-kDa protein associated with CD40. Proc Natl Acad Sci U S A. 1995 Dec 5; 92(25):11633-6.
    View in: PubMed
  195. Castigli E, Irani AM, Geha RS, Chatila T. Defective expression of early activation genes in cartilage-hair hypoplasia (CHH) with severe combined immunodeficiency (SCID). Clin Exp Immunol. 1995 Oct; 102(1):6-10.
    View in: PubMed
  196. Tsitsikov EN, Fuleihan R, McIntosh K, Scholl PR, Geha RS. Cross-linking of Fc gamma receptors activates HIV-1 long terminal repeat-driven transcription in human monocytes. Int Immunol. 1995 Oct; 7(10):1665-70.
    View in: PubMed
  197. Ramesh N, Morio T, Fuleihan R, Worm M, Horner A, Tsitsikov E, Castigli E, Geha RS. CD40-CD40 ligand (CD40L) interactions and X-linked hyperIgM syndrome (HIGMX-1). Clin Immunol Immunopathol. 1995 Sep; 76(3 Pt 2):S208-13.
    View in: PubMed
  198. Worm M, Geha RS. CD40-mediated lymphotoxin alpha expression in human B cells is tyrosine kinase dependent. Eur J Immunol. 1995 Sep; 25(9):2438-44.
    View in: PubMed
  199. Ramesh N, Horner A, Ahern D, Geha RS. Bacterial superantigens induce the proliferation of resting gamma/delta receptor bearing T cells. Immunol Invest. 1995 Aug; 24(5):713-24.
    View in: PubMed
  200. Trede NS, Tsytsykova AV, Chatila T, Goldfeld AE, Geha RS. Transcriptional activation of the human TNF-alpha promoter by superantigen in human monocytic cells: role of NF-kappa B. J Immunol. 1995 Jul 15; 155(2):902-8.
    View in: PubMed
  201. Fuleihan R, Ahern D, Geha RS. CD40 ligand expression is developmentally regulated in human thymocytes. Clin Immunol Immunopathol. 1995 Jul; 76(1 Pt 1):52-8.
    View in: PubMed
  202. Wang AV, Scholl PR, Geha RS. Association of the high-affinity receptor for IgG with the protein tyrosine kinases Hck and Lyn. Int Arch Allergy Immunol. 1995 May-Jun; 107(1-3):135.
    View in: PubMed
  203. Castigli E, Fuleihan R, Ramesh N, Tsitsikov E, Tsytsykova A, Geha RS. CD40 ligand/CD40 deficiency. Int Arch Allergy Immunol. 1995 May-Jun; 107(1-3):37-9.
    View in: PubMed
  204. Fuleihan R, Ahern D, Geha RS. Expression of the CD40 ligand in T lymphocytes and induction of IgE isotype switching. Int Arch Allergy Immunol. 1995 May-Jun; 107(1-3):43-4.
    View in: PubMed
  205. Worm M, Geha RS. Activation of tumor necrosis factor-alpha and lymphotoxin-alpha via anti-CD40 in human B cells. Int Arch Allergy Immunol. 1995 May-Jun; 107(1-3):368-9.
    View in: PubMed
  206. Jabara HH, Vercelli D, Schneider LC, Williams DP, Genbauffe FS, Poisson LR, Waters CA, Geha RS. Interleukin-4 receptor expression by human B cells: functional analysis with a human interleukin-4 toxin, DAB389IL-4. J Allergy Clin Immunol. 1995 Apr; 95(4):893-900.
    View in: PubMed
  207. Ramesh N, Fuleihan R, Swinton P, Rosen FS, Geha R. A point mutation in exon 2 of the CD40 ligand gene causes the simultaneous expression of two defective mRNA species in X-linked hyperimmunoglobulinemia M. Hum Mol Genet. 1995 Apr; 4(4):759-61.
    View in: PubMed
  208. Horner AA, Jabara H, Ramesh N, Geha RS. gamma/delta T lymphocytes express CD40 ligand and induce isotype switching in B lymphocytes. J Exp Med. 1995 Mar 1; 181(3):1239-44.
    View in: PubMed
  209. Loh RK, Jabara HH, Ren CL, Fu SM, Vercelli D, Geha RS. Role of protein tyrosine kinases and phosphatases in isotype switching: crosslinking CD45 to CD40 inhibits IgE isotype switching in human B cells. Immunol Lett. 1995 Feb; 45(1-2):99-106.
    View in: PubMed
  210. Fuleihan R, Ramesh N, Geha RS. X-linked agammaglobulinemia and immunoglobulin deficiency with normal or elevated IgM: immunodeficiencies of B cell development and differentiation. Adv Immunol. 1995; 60:37-56.
    View in: PubMed
  211. Castigli E, Alt FW, Davidson L, Bottaro A, Mizoguchi E, Bhan AK, Geha RS. CD40-deficient mice generated by recombination-activating gene-2-deficient blastocyst complementation. Proc Natl Acad Sci U S A. 1994 Dec 6; 91(25):12135-9.
    View in: PubMed
  212. Worm M, Geha RS. CD40 ligation induces lymphotoxin alpha gene expression in human B cells. Int Immunol. 1994 Dec; 6(12):1883-90.
    View in: PubMed
  213. Ren CL, Fu SM, Geha RS. Protein tyrosine kinase activation and protein kinase C translocation are functional components of CD40 signal transduction in resting human B cells. Immunol Invest. 1994 Nov; 23(6-7):437-48.
    View in: PubMed
  214. Ramesh N, Parronchi P, Ahern D, Romagnani S, Geha R. A toxic shock syndrome toxin-1 peptide that shows homology to amino acids 180-193 of mycobacterial heat shock protein 65 is presented as conventional antigen. Immunol Invest. 1994 Nov; 23(6-7):381-91.
    View in: PubMed
  215. Hoeger PH, Tepper MA, Faith A, Higgins JA, Lamb JR, Geha RS. Immunosuppressant deoxyspergualin inhibits antigen processing in monocytes. J Immunol. 1994 Nov 1; 153(9):3908-16.
    View in: PubMed
  216. Loh RK, Jabara HH, Ren CL, Fu SM, Geha RS. Role of protein tyrosine kinases in CD40/interleukin-4-mediated isotype switching to IgE. J Allergy Clin Immunol. 1994 Oct; 94(4):784-92.
    View in: PubMed
  217. Wang AV, Scholl PR, Geha RS. Physical and functional association of the high affinity immunoglobulin G receptor (Fc gamma RI) with the kinases Hck and Lyn. J Exp Med. 1994 Sep 1; 180(3):1165-70.
    View in: PubMed
  218. Scholl PR, Geha RS. MHC class II signaling in B-cell activation. Immunol Today. 1994 Sep; 15(9):418-22.
    View in: PubMed
  219. Fuleihan R, Trede N, Chatila T, Geha RS. Superantigens activate HIV-1 gene expression in monocytic cells. Clin Immunol Immunopathol. 1994 Sep; 72(3):357-61.
    View in: PubMed
  220. Spertini F, Wang AV, Chatila T, Geha RS. Engagement of the common leukocyte antigen CD45 induces homotypic adhesion of activated human T cells. J Immunol. 1994 Aug 15; 153(4):1593-602.
    View in: PubMed
  221. Fuleihan R, Ahern D, Geha RS. Decreased expression of the ligand for CD40 in newborn lymphocytes. Eur J Immunol. 1994 Aug; 24(8):1925-8.
    View in: PubMed
  222. Tsitsikov EN, Ramesh N, Geha RS. Structure of the murine CD40 ligand gene. Mol Immunol. 1994 Aug; 31(12):895-900.
    View in: PubMed
  223. Loh RK, Jabara HH, Geha RS. Disodium cromoglycate inhibits S mu-->S epsilon deletional switch recombination and IgE synthesis in human B cells. J Exp Med. 1994 Aug 1; 180(2):663-71.
    View in: PubMed
  224. Ramesh N, Fuleihan R, Geha R. Molecular pathology of X-linked immunoglobulin deficiency with normal or elevated IgM (HIGMX-1). Immunol Rev. 1994 Apr; 138:87-104.
    View in: PubMed
  225. Fuleihan R, Ramesh N, Horner A, Ahern D, Belshaw PJ, Alberg DG, Stamenkovic I, Harmon W, Geha RS. Cyclosporin A inhibits CD40 ligand expression in T lymphocytes. J Clin Invest. 1994 Mar; 93(3):1315-20.
    View in: PubMed
  226. Morio T, Geha RS, Chatila TA. Engagement of MHC class II molecules by staphylococcal superantigens activates src-type protein tyrosine kinases. Eur J Immunol. 1994 Mar; 24(3):651-8.
    View in: PubMed
  227. Ren CL, Morio T, Fu SM, Geha RS. Signal transduction via CD40 involves activation of lyn kinase and phosphatidylinositol-3-kinase, and phosphorylation of phospholipase C gamma 2. J Exp Med. 1994 Feb 1; 179(2):673-80.
    View in: PubMed
  228. Trede NS, Morio T, Scholl PR, Geha RS, Chatila T. Early activation events induced by the staphylococcal superantigen toxic shock syndrome toxin-1 in human peripheral blood monocytes. Clin Immunol Immunopathol. 1994 Feb; 70(2):137-44.
    View in: PubMed
  229. Fuleihan R, Ramesh N, Geha RS. Role of CD40-CD40-ligand interaction in Ig-isotype switching. Curr Opin Immunol. 1993 Dec; 5(6):963-7.
    View in: PubMed
  230. Jabara HH, Loh R, Ramesh N, Vercelli D, Geha RS. Sequential switching from mu to epsilon via gamma 4 in human B cells stimulated with IL-4 and hydrocortisone. J Immunol. 1993 Nov 1; 151(9):4528-33.
    View in: PubMed
  231. Geha R, Buckley CE, Greenberger P, Patterson R, Polmar S, Saxon A, Rohr A, Yang W, Drouin M. Aspartame is no more likely than placebo to cause urticaria/angioedema: results of a multicenter, randomized, double-blind, placebo-controlled, crossover study. J Allergy Clin Immunol. 1993 Oct; 92(4):513-20.
    View in: PubMed
  232. Scholl PR, Geha RS. Physical association between the high-affinity IgG receptor (Fc gamma RI) and the gamma subunit of the high-affinity IgE receptor (Fc epsilon RI gamma). Proc Natl Acad Sci U S A. 1993 Oct 1; 90(19):8847-50.
    View in: PubMed
  233. Trede NS, Chatila T, Geha RS. Activator protein-1 (AP-1) is stimulated by microbial superantigens in human monocytic cells. Eur J Immunol. 1993 Sep; 23(9):2129-35.
    View in: PubMed
  234. Barlan IB, Geha RS, Schneider LC. Therapy for patients with recurrent infections and low serum IgG3 levels. J Allergy Clin Immunol. 1993 Aug; 92(2):353-5.
    View in: PubMed
  235. Ramesh N, Fuleihan R, Ramesh V, Lederman S, Yellin MJ, Sharma S, Chess L, Rosen FS, Geha RS. Deletions in the ligand for CD40 in X-linked immunoglobulin deficiency with normal or elevated IgM (HIGMX-1). Int Immunol. 1993 Jul; 5(7):769-73.
    View in: PubMed
  236. Trede NS, Castigli E, Geha RS, Chatila T. Microbial superantigens induce NF-kappa B in the human monocytic cell line THP-1. J Immunol. 1993 Jun 15; 150(12):5604-13.
    View in: PubMed
  237. Castigli E, Pahwa R, Good RA, Geha RS, Chatila TA. Molecular basis of a multiple lymphokine deficiency in a patient with severe combined immunodeficiency. Proc Natl Acad Sci U S A. 1993 May 15; 90(10):4728-32.
    View in: PubMed
  238. Ramesh N, Ramesh V, Gusella JF, Geha R. Chromosomal localization of the gene for human B-cell antigen CD40. Somat Cell Mol Genet. 1993 May; 19(3):295-8.
    View in: PubMed
  239. Castigli E, Chatila TA, Geha RS. A protein of the AP-1 family is a component of nuclear factor of activated T cells. J Immunol. 1993 Apr 15; 150(8 Pt 1):3284-90.
    View in: PubMed
  240. Fuleihan R, Ramesh N, Loh R, Jabara H, Rosen RS, Chatila T, Fu SM, Stamenkovic I, Geha RS. Defective expression of the CD40 ligand in X chromosome-linked immunoglobulin deficiency with normal or elevated IgM. Proc Natl Acad Sci U S A. 1993 Mar 15; 90(6):2170-3.
    View in: PubMed
  241. Chatila T, Geha RS. Signal transduction by microbial superantigens via MHC class II molecules. Immunol Rev. 1993 Feb; 131:43-59.
    View in: PubMed
  242. Vercelli D, Geha RS. Regulation of IgE synthesis: from the membrane to the genes. Springer Semin Immunopathol. 1993; 15(1):5-16.
    View in: PubMed
  243. Castigli E, Geha RS, Chatila T. Severe combined immunodeficiency with selective T-cell cytokine genes. Pediatr Res. 1993 Jan; 33(1 Suppl):S20-2; discussion S22-3.
    View in: PubMed
  244. Fuleihan R, Ramesh N, Rosen FS, Geha RS. Localization of the genetic defect in X-linked immunoglobulin deficiency with normal or elevated IgM (HIGMX-1) to the CD40 ligand gene. Trans Assoc Am Physicians. 1993; 106:91-5.
    View in: PubMed
  245. Vercelli D, Geha RS. Regulation of isotype switching. Curr Opin Immunol. 1992 Dec; 4(6):794-7.
    View in: PubMed
  246. al-Rayes H, Pachas W, Mirza N, Ahern DJ, Geha RS, Vercelli D. IgE regulation and lymphokine patterns in aging humans. J Allergy Clin Immunol. 1992 Oct; 90(4 Pt 1):630-6.
    View in: PubMed
  247. Fuleihan R, Spertini F, Geha RS, Chatila T. Role of protein kinase activation in the induction of B cell adhesion by MHC class II ligands. J Immunol. 1992 Sep 15; 149(6):1853-8.
    View in: PubMed
  248. Scholl PR, Ahern D, Geha RS. Protein tyrosine phosphorylation induced via the IgG receptors Fc gamma Ri and Fc gamma RII in the human monocytic cell line THP-1. J Immunol. 1992 Sep 1; 149(5):1751-7.
    View in: PubMed
  249. Geha RS. Regulation of IgE synthesis in humans. J Allergy Clin Immunol. 1992 Aug; 90(2):143-50.
    View in: PubMed
  250. Spertini F, Chatila T, Geha RS. Signals delivered via MHC class II molecules synergize with signals delivered via TCR/CD3 to cause proliferation and cytokine gene expression in T cells. J Immunol. 1992 Jul 1; 149(1):65-70.
    View in: PubMed
  251. Spertini F, Chatila T, Geha RS. Engagement of MHC class I molecules induces cell adhesion via both LFA-1-dependent and LFA-1-independent pathways. J Immunol. 1992 Apr 1; 148(7):2045-9.
    View in: PubMed
  252. Scholl PR, Trede N, Chatila TA, Geha RS. Role of protein tyrosine phosphorylation in monokine induction by the staphylococcal superantigen toxic shock syndrome toxin-1. J Immunol. 1992 Apr 1; 148(7):2237-41.
    View in: PubMed
  253. Sancho J, Silverman LB, Castigli E, Ahern D, Laudano AP, Terhorst C, Geha RS, Chatila TA. Developmental regulation of transmembrane signaling via the T cell antigen receptor/CD3 complex in human T lymphocytes. J Immunol. 1992 Mar 1; 148(5):1315-21.
    View in: PubMed
  254. Ramesh N, Spertini F, Scholl P, Geha R. A toxic shock syndrome toxin-1 peptide that shows homology to mycobacterial heat shock protein 18 is presented as conventional antigen to T cells by multiple HLA-DR alleles. J Immunol. 1992 Feb 15; 148(4):1025-30.
    View in: PubMed
  255. Chatila T, Geha RS. Superantigens. Curr Opin Immunol. 1992 Feb; 4(1):74-8.
    View in: PubMed
  256. Chatila T, Scholl P, Ramesh N, Trede N, Fuleihan R, Morio T, Geha RS. Cellular and molecular mechanisms of immune activation by microbial superantigens: studies using toxic shock syndrome toxin-1. Chem Immunol. 1992; 55:146-71.
    View in: PubMed
  257. Shapira SK, Vercelli D, Jabara HH, Fu SM, Geha RS. Molecular analysis of the induction of immunoglobulin E synthesis in human B cells by interleukin 4 and engagement of CD40 antigen. J Exp Med. 1992 Jan 1; 175(1):289-92.
    View in: PubMed
  258. Schneider LC, Antin JH, Weinstein H, Abrams JS, Pearce MK, Geha RS, Vercelli D. Lymphokine profile in bone marrow transplant recipients. Blood. 1991 Dec 1; 78(11):3076-80.
    View in: PubMed
  259. Maguire JF, O'Rourke PP, Colan SD, Geha RS, Crone R. Cardiotoxicity during treatment of severe childhood asthma. Pediatrics. 1991 Dec; 88(6):1180-6.
    View in: PubMed
  260. Geha RS, Castigli E, Chatila T. Novel immune deficiencies: defective transcription of lymphokine genes. Clin Immunol Immunopathol. 1991 Nov; 61(2 Pt 2):S16-20.
    View in: PubMed
  261. Shapira SK, Jabara HH, Thienes CP, Ahern DJ, Vercelli D, Gould HJ, Geha RS. Deletional switch recombination occurs in interleukin-4-induced isotype switching to IgE expression by human B cells. Proc Natl Acad Sci U S A. 1991 Sep 1; 88(17):7528-32.
    View in: PubMed
  262. Vercelli D, Geha RS. Regulation of IgE synthesis in humans: a tale of two signals. J Allergy Clin Immunol. 1991 Sep; 88(3 Pt 1):285-95.
    View in: PubMed
  263. Spertini F, Spits H, Geha RS. Staphylococcal exotoxins deliver activation signals to human T-cell clones via major histocompatibility complex class II molecules. Proc Natl Acad Sci U S A. 1991 Sep 1; 88(17):7533-7.
    View in: PubMed
  264. Jabara HH, Ahern DJ, Vercelli D, Geha RS. Hydrocortisone and IL-4 induce IgE isotype switching in human B cells. J Immunol. 1991 Sep 1; 147(5):1557-60.
    View in: PubMed
  265. Lue KH, Lauener RP, Winchester RJ, Geha RS, Vercelli D. Engagement of CD14 on human monocytes terminates T cell proliferation by delivering a negative signal to T cells. J Immunol. 1991 Aug 15; 147(4):1134-8.
    View in: PubMed
  266. Trede NS, Geha RS, Chatila T. Transcriptional activation of IL-1 beta and tumor necrosis factor-alpha genes by MHC class II ligands. J Immunol. 1991 Apr 1; 146(7):2310-5.
    View in: PubMed
  267. Fuleihan R, Mourad W, Geha RS, Chatila T. Engagement of MHC-class II molecules by staphylococcal exotoxins delivers a comitogenic signal to human B cells. J Immunol. 1991 Mar 1; 146(5):1661-6.
    View in: PubMed
  268. Spertini F, Stohl W, Ramesh N, Moody C, Geha RS. Induction of human T cell proliferation by a monoclonal antibody to CD5. J Immunol. 1991 Jan 1; 146(1):47-52.
    View in: PubMed
  269. Geha RS, Castigli E, Chatila T. Novel immune deficiencies: defective transcription of lymphokine genes. Clin Exp Allergy. 1991 Jan; 21 Suppl 1:190-4.
    View in: PubMed
  270. Chatila T, Scholl P, Spertini F, Ramesh N, Trede N, Fuleihan R, Geha RS. Toxic shock syndrome toxin-1, toxic shock, and the immune system. Curr Top Microbiol Immunol. 1991; 174:63-79.
    View in: PubMed
  271. Jabara HH, Fu SM, Geha RS, Vercelli D. CD40 and IgE: synergism between anti-CD40 monoclonal antibody and interleukin 4 in the induction of IgE synthesis by highly purified human B cells. J Exp Med. 1990 Dec 1; 172(6):1861-4.
    View in: PubMed
  272. Chatila T, Castigli E, Pahwa R, Pahwa S, Chirmule N, Oyaizu N, Good RA, Geha RS. Primary combined immunodeficiency resulting from defective transcription of multiple T-cell lymphokine genes. Proc Natl Acad Sci U S A. 1990 Dec; 87(24):10033-7.
    View in: PubMed
  273. Jabara HH, Schneider LC, Shapira SK, Alfieri C, Moody CT, Kieff E, Geha RS, Vercelli D. Induction of germ-line and mature C epsilon transcripts in human B cells stimulated with rIL-4 and EBV. J Immunol. 1990 Nov 15; 145(10):3468-73.
    View in: PubMed
  274. Mourad W, Geha RS, Chatila T. Engagement of major histocompatibility complex class II molecules induces sustained, lymphocyte function-associated molecule 1-dependent cell adhesion. J Exp Med. 1990 Nov 1; 172(5):1513-6.
    View in: PubMed
  275. Lauener RP, Goyert SM, Geha RS, Vercelli D. Interleukin 4 down-regulates the expression of CD14 in normal human monocytes. Eur J Immunol. 1990 Nov; 20(11):2375-81.
    View in: PubMed
  276. Scholl PR, Sekaly RP, Diez A, Glimcher LH, Geha RS. Binding of toxic shock syndrome toxin-1 to murine major histocompatibility complex class II molecules. Eur J Immunol. 1990 Sep; 20(9):1911-6.
    View in: PubMed
  277. Lauener RP, Geha RS, Vercelli D. Engagement of the monocyte surface antigen CD14 induces lymphocyte function-associated antigen-1/intercellular adhesion molecule-1-dependent homotypic adhesion. J Immunol. 1990 Sep 1; 145(5):1390-4.
    View in: PubMed
  278. Schneider LC, Insel RA, Howie G, Madore DV, Geha RS. Response to a Haemophilus influenzae type b diphtheria CRM197 conjugate vaccine in children with a defect of antibody production to Haemophilus influenzae type b polysaccharide. J Allergy Clin Immunol. 1990 May; 85(5):948-53.
    View in: PubMed
  279. Schneider LC, Berman RS, Shea CR, Perez-Atayde AR, Weinstein H, Geha RS. Bone marrow transplantation (BMT) for the syndrome of pigmentary dilution and lymphohistiocytosis (Griscelli's syndrome). J Clin Immunol. 1990 May; 10(3):146-53.
    View in: PubMed
  280. Vercelli D, Jabara HH, Cunningham-Rundles C, Abrams JS, Lewis DB, Meyer J, Schneider LC, Leung DY, Geha RS. Regulation of immunoglobulin (Ig)E synthesis in the hyper-IgE syndrome. J Clin Invest. 1990 May; 85(5):1666-71.
    View in: PubMed
  281. Boguniewicz M, Jaffe HS, Izu A, Sullivan MJ, York D, Geha RS, Leung DY. Recombinant gamma interferon in treatment of patients with atopic dermatitis and elevated IgE levels. Am J Med. 1990 Apr; 88(4):365-70.
    View in: PubMed
  282. Wong RC, Remold-O'Donnell E, Vercelli D, Sancho J, Terhorst C, Rosen F, Geha R, Chatila T. Signal transduction via leukocyte antigen CD43 (sialophorin). Feedback regulation by protein kinase C. J Immunol. 1990 Feb 15; 144(4):1455-60.
    View in: PubMed
  283. Vercelli D, Jabara HH, Lauener RP, Geha RS. IL-4 inhibits the synthesis of IFN-gamma and induces the synthesis of IgE in human mixed lymphocyte cultures. J Immunol. 1990 Jan 15; 144(2):570-3.
    View in: PubMed
  284. Scholl PR, Diez A, Karr R, Sekaly RP, Trowsdale J, Geha RS. Effect of isotypes and allelic polymorphism on the binding of staphylococcal exotoxins to MHC class II molecules. J Immunol. 1990 Jan 1; 144(1):226-30.
    View in: PubMed
  285. Sancho J, Chatila T, Wong RC, Hall C, Blumberg R, Alarcon B, Geha RS, Terhorst C. T-cell antigen receptor (TCR)-alpha/beta heterodimer formation is a prerequisite for association of CD3-zeta 2 into functionally competent TCR.CD3 complexes. J Biol Chem. 1989 Dec 5; 264(34):20760-9.
    View in: PubMed
  286. Mourad W, Scholl P, Diaz A, Geha R, Chatila T. The staphylococcal toxic shock syndrome toxin 1 triggers B cell proliferation and differentiation via major histocompatibility complex-unrestricted cognate T/B cell interaction. J Exp Med. 1989 Dec 1; 170(6):2011-22.
    View in: PubMed
  287. Chatila TA, Geha RS, Arnaout MA. Constitutive and stimulus-induced phosphorylation of CD11/CD18 leukocyte adhesion molecules. J Cell Biol. 1989 Dec; 109(6 Pt 2):3435-44.
    View in: PubMed
  288. Scholl PR, Diez A, Geha RS. Staphylococcal enterotoxin B and toxic shock syndrome toxin-1 bind to distinct sites on HLA-DR and HLA-DQ molecules. J Immunol. 1989 Oct 15; 143(8):2583-8.
    View in: PubMed
  289. Chatila T, Silverman L, Miller R, Geha R. Mechanisms of T cell activation by the calcium ionophore ionomycin. J Immunol. 1989 Aug 15; 143(4):1283-9.
    View in: PubMed
  290. Vercelli D, Jabara HH, Arai K, Yokota T, Geha RS. Endogenous interleukin 6 plays an obligatory role in interleukin 4-dependent human IgE synthesis. Eur J Immunol. 1989 Aug; 19(8):1419-24.
    View in: PubMed
  291. Geha RS, Rosen FS. The evolution of MHC restrictions in antigen recognition by T cells in a haploidentical bone marrow transplant recipient. J Immunol. 1989 Jul 1; 143(1):84-8.
    View in: PubMed
  292. Vercelli D, Geha RS. The IgE system. Ann Allergy. 1989 Jul; 63(1):4-11.
    View in: PubMed
  293. Silverman LB, Wong RC, Remold-O'Donnell E, Vercelli D, Sancho J, Terhorst C, Rosen F, Geha R, Chatila T. Mechanism of mononuclear cell activation by an anti-CD43 (sialophorin) agonistic antibody. J Immunol. 1989 Jun 15; 142(12):4194-200.
    View in: PubMed
  294. Scholl P, Diez A, Mourad W, Parsonnet J, Geha RS, Chatila T. Toxic shock syndrome toxin 1 binds to major histocompatibility complex class II molecules. Proc Natl Acad Sci U S A. 1989 Jun; 86(11):4210-4.
    View in: PubMed
  295. Vercelli D, Helm B, Marsh P, Padlan E, Geha RS, Gould H. The B-cell binding site on human immunoglobulin E. Nature. 1989 Apr 20; 338(6217):649-51.
    View in: PubMed
  296. Vercelli D, Jabara HH, Arai K, Geha RS. Induction of human IgE synthesis requires interleukin 4 and T/B cell interactions involving the T cell receptor/CD3 complex and MHC class II antigens. J Exp Med. 1989 Apr 1; 169(4):1295-307.
    View in: PubMed
  297. Chatila T, Wong R, Young M, Miller R, Terhorst C, Geha RS. An immunodeficiency characterized by defective signal transduction in T lymphocytes. N Engl J Med. 1989 Mar 16; 320(11):696-702.
    View in: PubMed
  298. Lee BW, Simmons CF, Wileman T, Geha RS. Intracellular cleavage of newly synthesized low affinity Fc epsilon receptor (Fc epsilon R2) provides a second pathway for the generation of the 28-kDa soluble Fc epsilon R2 fragment. J Immunol. 1989 Mar 1; 142(5):1614-20.
    View in: PubMed
  299. Vercelli D, Geha RS. Regulation of IgE synthesis in humans. J Clin Immunol. 1989 Mar; 9(2):75-83.
    View in: PubMed
  300. Schwartz D, Wong RC, Chatila T, Arnaout A, Miller R, Geha R. Proliferation of highly purified T cells in response to signaling via surface receptors requires cell-cell contact. J Clin Immunol. 1989 Mar; 9(2):151-8.
    View in: PubMed
  301. Geha RS, Leung DY. Hyper immunoglobulin E syndrome. Immunodefic Rev. 1989; 1(2):155-72.
    View in: PubMed
  302. Vercelli D, Leung DY, Jabara HH, Geha RS. Interleukin 4 dependent induction of IgE synthesis and CD23 expression by the supernatants of a human helper T cell clone. Int Arch Allergy Appl Immunol. 1989; 88(1-2):119-21.
    View in: PubMed
  303. Vercelli D, Jabara HH, Geha RS. Regulation of human IgE synthesis. Int Rev Immunol. 1989; 5(2):111-5.
    View in: PubMed
  304. Lee BW, Geha RS, Leung DY. IgE response and its regulation in allergic diseases. Pediatr Clin North Am. 1988 Oct; 35(5):953-67.
    View in: PubMed
  305. Chatila TA, Geha RS. Phosphorylation of T cell membrane proteins by activators of protein kinase C. J Immunol. 1988 Jun 15; 140(12):4308-14.
    View in: PubMed
  306. Leung DY, Ambrosino DM, Arbeit RD, Newton JL, Geha RS. Impaired antibody responses in the hyperimmunoglobulin E syndrome. J Allergy Clin Immunol. 1988 Jun; 81(6):1082-7.
    View in: PubMed
  307. Geha RS. Antibody deficiency syndromes and novel immunodeficiencies. Pediatr Infect Dis J. 1988 May; 7(5 Suppl):S57-60.
    View in: PubMed
  308. Umetsu DT, Jabara HH, Hauschka P, Geha RS. Recognition by a human alloreactive T-cell clone of an HLA-DP-associated epitope on monocytes and fibroblasts but not on B cells. J Clin Immunol. 1988 May; 8(3):163-70.
    View in: PubMed
  309. Vercelli D, Jabara HH, Lee BW, Woodland N, Geha RS, Leung DY. Human recombinant interleukin 4 induces Fc epsilon R2/CD23 on normal human monocytes. J Exp Med. 1988 Apr 1; 167(4):1406-16.
    View in: PubMed
  310. Leung DY, Geha RS. Clinical and immunologic aspects of the hyperimmunoglobulin E syndrome. Hematol Oncol Clin North Am. 1988 Mar; 2(1):81-100.
    View in: PubMed
  311. Geha RS. Regulation of IgE synthesis in atopic disease. Hosp Pract (Off Ed). 1988 Feb 15; 23(2):91-102.
    View in: PubMed
  312. Chatila T, Wood N, Parsonnet J, Geha RS. Toxic shock syndrome toxin-1 induces inositol phospholipid turnover, protein kinase C translocation, and calcium mobilization in human T cells. J Immunol. 1988 Feb 15; 140(4):1250-5.
    View in: PubMed
  313. Silk H, Geha RS. Asthma, recurrent infections and IgG2 deficiency. Ann Allergy. 1988 Feb; 60(2):98, 134-6.
    View in: PubMed
  314. Silk HJ, Guay-Woodford L, Perez-Atayde AR, Geha RS, Broff MD. Fatal varicella in steroid-dependent asthma. J Allergy Clin Immunol. 1988 Jan; 81(1):47-51.
    View in: PubMed
  315. Leung DY, Key L, Steinberg JJ, Young MC, Von Deck M, Wilkinson R, Geha RS. Increased in vitro bone resorption by monocytes in the hyper-immunoglobulin E syndrome. J Immunol. 1988 Jan 1; 140(1):84-8.
    View in: PubMed
  316. Geha RS. IgG antibody response to polysaccharides in children with recurrent infections. Monogr Allergy. 1988; 23:97-102.
    View in: PubMed
  317. Geha RS. Cell cooperation in haploidentical bone marrow transplant recipient. Transplant Proc. 1987 Dec; 19(6 Suppl 7):117-21.
    View in: PubMed
  318. Umetsu DT, Katzen D, Chatila T, Miller R, Jabara HH, Maher M, Oettgen H, Terhorst C, Geha RS. Requirements for activation of human peripheral blood T cells by mouse monoclonal antibodies to CD3. Clin Immunol Immunopathol. 1987 Apr; 43(1):48-64.
    View in: PubMed
  319. Leung DY, Schneeberger EE, Siraganian RP, Geha RS, Bhan AK. The presence of IgE on macrophages and dendritic cells infiltrating into the skin lesion of atopic dermatitis. Clin Immunol Immunopathol. 1987 Mar; 42(3):328-37.
    View in: PubMed
  320. Burns JC, Geha RS, Newburger JW, Huang AS, Leung DY. Polymerase activity in lymphocyte culture supernatants from patients with Kawasaki disease. Prog Clin Biol Res. 1987; 250:125-30.
    View in: PubMed
  321. Leung DY, Geha RS. Regulation of the human IgE antibody response. Int Rev Immunol. 1987 Jan; 2(1):75-91.
    View in: PubMed
  322. Burns JC, Geha RS, Schneeberger EE, Newburger JW, Rosen FS, Glezen LS, Huang AS, Natale J, Leung DY. Polymerase activity in lymphocyte culture supernatants from patients with Kawasaki disease. Nature. 1986 Oct 30-Nov 5; 323(6091):814-6.
    View in: PubMed
  323. Leung DY, Collins T, Lapierre LA, Geha RS, Pober JS. Immunoglobulin M antibodies present in the acute phase of Kawasaki syndrome lyse cultured vascular endothelial cells stimulated by gamma interferon. J Clin Invest. 1986 May; 77(5):1428-35.
    View in: PubMed
  324. Chu E, Umetsu D, Lareau M, Schneeberger E, Geha RS. Analysis of antigen uptake and presentation by Epstein-Barr virus-transformed human lymphoblastoid B cells. Eur J Immunol. 1984 Apr; 14(4):291-8.
    View in: PubMed
  325. Brozek C, Umetsu D, Schneeberger E, Geha RS. Mechanisms of the failure of resting B cells to present tetanus toxoid antigen to T cells. J Immunol. 1984 Mar; 132(3):1144-50.
    View in: PubMed
  326. Leung DY, Bhan AK, Schneeberger EE, Geha RS. Characterization of the mononuclear cell infiltrate in atopic dermatitis using monoclonal antibodies. J Allergy Clin Immunol. 1983 Jan; 71(1 Pt 1):47-56.
    View in: PubMed
  327. Alpert SD, Jonsen ME, Broff MD, Schneeberger E, Geha RS. Macrophage T-cell interaction in man: handling of tetanus toxoid antigen by human monocytes. J Clin Immunol. 1981 Jan; 1(1):21-9.
    View in: PubMed
  328. Geha RS, Hyslop N, Alami S, Farah F, Schneeberger EE, Rosen FS. Hyper immunoglobulin M immunodeficiency. (Dysgammaglobulinemia). Presence of immunoglobulin M-secreting plasmacytoid cells in peripheral blood and failure of immunoglobulin M-immunoglobulin G switch in B-cell differentiation. J Clin Invest. 1979 Aug; 64(2):385-91.
    View in: PubMed
  329. Geha RS, Mudawwar F, Schneeberger E. The specificity of T-cell helper factor in man. J Exp Med. 1977 Jun 1; 145(6):1436-48.
    View in: PubMed
  330. Geha RS, Colten HR, Schneeberger E, Merler E. Cooperation between human thymus-derived and bone marrow-derived lymphocytes in the antibody response to ragweed antigen E in vitro. J Clin Invest. 1975 Aug; 56(2):386-90.
    View in: PubMed
  331. Geha RS, Schneeberger E, Merler E, Rosen FS. Heterogeneity of "acquired" or common variable agammaglobulinemia. N Engl J Med. 1974 Jul 4; 291(1):1-6.
    View in: PubMed
  332. Geha RS, Schneeberger E, Gatien J, Rosen FS, Merler E. Synthesis of an M component by circulating B lymphocytes in severe combined immunodeficiency. N Engl J Med. 1974 Mar 28; 290(13):726-8.
    View in: PubMed
  333. Geha RS, Schneeberger E, Rosen FS, Merler E. Interaction of human thymus-derived and non-thymus-derived lymphocytes in vitro. Induction of proliferation and antibody synthesis in B lymphocytes by a soluble factor released from antigen-stimulated T lymphocytes. J Exp Med. 1973 Nov 1; 138(5):1230-47.
    View in: PubMed
Local representatives can answer questions about the Profiles website or help with editing a profile or issues with profile data. For assistance with this profile: HMS/HSDM faculty should contact Human Resources at faculty_serviceshms.harvard.edu.
Geha's Networks
Click the "See All" links for more information and interactive visualizations!
Concepts
_
Co-Authors
_
Similar People
_
Same Department
Physical Neighbors
_