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William Charles Dewolf, M.D.

TitleBeth Israel Deaconess Medical Center Professor of Surgery
InstitutionBeth Israel Deaconess Medical Center
DepartmentSurgery
AddressBeth Israel Deaconess Med Ctr
Surgery
330 Brookline Ave
Boston MA 02215
Phone617/667-8903
Fax617/667-7292

 Bibliographic 
 selected publications
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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  1. Bloch BN, Genega EM, Costa DN, Pedrosa I, Smith MP, Kressel HY, Ngo L, Sanda MG, Dewolf WC, Rofsky NM. Prediction of prostate cancer extracapsular extension with high spatial resolution dynamic contrast-enhanced 3-T MRI. Eur Radiol. 2012 Oct; 22(10):2201-10.
    View in: PubMed
  2. Chang P, Szymanski KM, Dunn RL, Chipman JJ, Litwin MS, Nguyen PL, Sweeney CJ, Cook R, Wagner AA, DeWolf WC, Bubley GJ, Funches R, Aronovitz JA, Wei JT, Sanda MG. Expanded prostate cancer index composite for clinical practice: development and validation of a practical health related quality of life instrument for use in the routine clinical care of patients with prostate cancer. J Urol. 2011 Sep; 186(3):865-72.
    View in: PubMed
  3. San Francisco IF, Werner L, Regan MM, Garnick MB, Bubley G, DeWolf WC. Risk stratification and validation of prostate specific antigen density as independent predictor of progression in men with low risk prostate cancer during active surveillance. J Urol. 2011 Feb; 185(2):471-6.
    View in: PubMed
  4. Dewolf WC. Re: Pretreatment neutrophil-to-lymphocyte ratio as an independent predictor of recurrence in patients with nonmetastatic renal cell carcinoma. Editorial comment. J Urol. 2010 Sep; 184(3):878.
    View in: PubMed
  5. Schopperle WM, Lee JM, Dewolf WC. The human cancer and stem cell marker podocalyxin interacts with the glucose-3-transporter in malignant pluripotent stem cells. Biochem Biophys Res Commun. 2010 Jul 30; 398(3):372-6.
    View in: PubMed
  6. Lee KS, Zeikus E, DeWolf WC, Rofsky NM, Pedrosa I. MR urography versus retrograde pyelography/ureteroscopy for the exclusion of upper urinary tract malignancy. Clin Radiol. 2010 Mar; 65(3):185-92.
    View in: PubMed
  7. Olumi AF, Dewolf WC. The hybrid of basic science and clinical training for the urologic oncologist: Necessity or waste? Urol Oncol. 2009 Mar-Apr; 27(2):205-7.
    View in: PubMed
  8. Pedrosa I, Sun MR, Spencer M, Genega EM, Olumi AF, Dewolf WC, Rofsky NM. MR imaging of renal masses: correlation with findings at surgery and pathologic analysis. Radiographics. 2008 Jul-Aug; 28(4):985-1003.
    View in: PubMed
  9. Dewolf WC. Re: are doctors examining prostates in university hospital? Eur Urol. 2008 Jun; 53(6):1296-7.
    View in: PubMed
  10. Adey GS, Pedrosa I, Rofsky NM, Sanda MG, DeWolf WC. Lower limits of detection using magnetic resonance imaging for solid components in cystic renal neoplasms. Urology. 2008 Jan; 71(1):47-51.
    View in: PubMed
  11. Zhang X, Zhang L, Yang H, Huang X, Otu H, Libermann TA, DeWolf WC, Khosravi-Far R, Olumi AF. c-Fos as a proapoptotic agent in TRAIL-induced apoptosis in prostate cancer cells. Cancer Res. 2007 Oct 1; 67(19):9425-34.
    View in: PubMed
  12. Pedrosa I, Chou MT, Ngo L, H Baroni R, Genega EM, Galaburda L, DeWolf WC, Rofsky NM. MR classification of renal masses with pathologic correlation. Eur Radiol. 2008 Feb; 18(2):365-75.
    View in: PubMed
  13. Kerfoot BP, DeWolf WC, Masser BA, Church PA, Federman DD. Spaced education improves the retention of clinical knowledge by medical students: a randomised controlled trial. Med Educ. 2007 Jan; 41(1):23-31.
    View in: PubMed
  14. Schopperle WM, DeWolf WC. The TRA-1-60 and TRA-1-81 human pluripotent stem cell markers are expressed on podocalyxin in embryonal carcinoma. Stem Cells. 2007 Mar; 25(3):723-30.
    View in: PubMed
  15. Kerfoot BP, Masser BA, Dewolf WC. The continued decline of formal urological education of medical students in the United States: does it matter? J Urol. 2006 Jun; 175(6):2243-7; discussion 2247-8.
    View in: PubMed
  16. San Francisco IF, Regan MM, Dewolf WC, Olumi AF. Low age adjusted free testosterone levels correlate with poorly differentiated prostate cancer. J Urol. 2006 Apr; 175(4):1341-5; discussion 1345-6.
    View in: PubMed
  17. Kerfoot BP, Baker H, Jackson TL, Hulbert WC, Federman DD, Oates RD, DeWolf WC. A multi-institutional randomized controlled trial of adjuvant Web-based teaching to medical students. Acad Med. 2006 Mar; 81(3):224-30.
    View in: PubMed
  18. Ramsawh HJ, Morgentaler A, Covino N, Barlow DH, DeWolf WC. Quality of life following simultaneous placement of penile prosthesis with radical prostatectomy. J Urol. 2005 Oct; 174(4 Pt 1):1395-8.
    View in: PubMed
  19. Hutchinson LM, Chang EL, Becker CM, Shih MC, Brice M, DeWolf WC, Gaston SM, Zetter BR. Use of thymosin beta15 as a urinary biomarker in human prostate cancer. Prostate. 2005 Jul 1; 64(2):116-27.
    View in: PubMed
  20. Johnson TR, Pedrosa I, Goldsmith J, Dewolf WC, Rofsky NM. Magnetic resonance imaging findings in solitary fibrous tumor of the kidney. J Comput Assist Tomogr. 2005 Jul-Aug; 29(4):481-3.
    View in: PubMed
  21. Hutchinson LM, Chang EL, Becker CM, Ushiyama N, Behonick D, Shih MC, DeWolf WC, Gaston SM, Zetter BR. Development of a sensitive and specific enzyme-linked immunosorbent assay for thymosin beta15, a urinary biomarker of human prostate cancer. Clin Biochem. 2005 Jun; 38(6):558-71.
    View in: PubMed
  22. San Francisco IF, DeWolf WC, Peehl DM, Olumi AF. Expression of transforming growth factor-beta 1 and growth in soft agar differentiate prostate carcinoma-associated fibroblasts from normal prostate fibroblasts. Int J Cancer. 2004 Nov 1; 112(2):213-8.
    View in: PubMed
  23. Zhang X, Jin TG, Yang H, DeWolf WC, Khosravi-Far R, Olumi AF. Persistent c-FLIP(L) expression is necessary and sufficient to maintain resistance to tumor necrosis factor-related apoptosis-inducing ligand-mediated apoptosis in prostate cancer. Cancer Res. 2004 Oct 1; 64(19):7086-91.
    View in: PubMed
  24. Sosna J, Pedrosa I, Dewolf WC, Mahallati H, Lenkinski RE, Rofsky NM. MR imaging of the prostate at 3 Tesla: comparison of an external phased-array coil to imaging with an endorectal coil at 1.5 Tesla. Acad Radiol. 2004 Aug; 11(8):857-62.
    View in: PubMed
  25. Kerfoot BP, Baker H, Volkan K, Church PA, Federman DD, Masser BA, DeWolf WC. Development and initial evaluation of a novel urology curriculum for medical students. J Urol. 2004 Jul; 172(1):278-81.
    View in: PubMed
  26. Kerfoot BP, Baker H, Volkan K, Church PA, Federman DD, Masser BA, DeWOLF WC. Development of validated instrument to measure medical student learning in clinical urology: a step toward evidence based education. J Urol. 2004 Jul; 172(1):282-5.
    View in: PubMed
  27. Kamel IR, Hochman MG, Keogan MT, Eng J, Longmaid HE, DeWolf W, Edelman RR. Accuracy of breath-hold magnetic resonance imaging in preoperative staging of organ-confined renal cell carcinoma. J Comput Assist Tomogr. 2004 May-Jun; 28(3):327-32.
    View in: PubMed
  28. DeWolf WC, Gaston SM. The cell cycle and its relevance to the urologist. J Urol. 2004 Apr; 171(4):1674-81.
    View in: PubMed
  29. San Francisco IF, Regan MM, Olumi AF, DeWolf WC. Percent of cores positive for cancer is a better preoperative predictor of cancer recurrence after radical prostatectomy than prostate specific antigen. J Urol. 2004 Apr; 171(4):1492-9.
    View in: PubMed
  30. George DJ, Regan MM, Oh WK, Tay MH, Manola J, Decalo N, Duggan S, Dewolf WC, Kantoff PW, Bubley GJ. Radical prostatectomy lowers plasma vascular endothelial growth factor levels in patients with prostate cancer. Urology. 2004 Feb; 63(2):327-32.
    View in: PubMed
  31. San Francisco IF, Olumi AF, Yoon JH, Regan MM, DeWolf WC. Preoperative serum acid phosphatase and alkaline phosphatase are not predictors of pathological stage and prostate-specific antigen failure after radical prostatectomy. BJU Int. 2003 Dec; 92(9):924-8.
    View in: PubMed
  32. Spentzos D, Mantzoros C, Regan MM, Morrissey ME, Duggan S, Flickner-Garvey S, McCormick H, DeWolf W, Balk S, Bubley GJ. Minimal effect of a low-fat/high soy diet for asymptomatic, hormonally naive prostate cancer patients. Clin Cancer Res. 2003 Aug 15; 9(9):3282-7.
    View in: PubMed
  33. Sosna J, Rofsky NM, Gaston SM, DeWolf WC, Lenkinski RE. Determinations of prostate volume at 3-Tesla using an external phased array coil: comparison to pathologic specimens. Acad Radiol. 2003 Aug; 10(8):846-53.
    View in: PubMed
  34. San Francisco IF, Olumi AF, Kao J, Rosen S, DeWolf WC. Clinical management of prostatic intraepithelial neoplasia as diagnosed by extended needle biopsies. BJU Int. 2003 Mar; 91(4):350-4.
    View in: PubMed
  35. Schopperle WM, Kershaw DB, DeWolf WC. Human embryonal carcinoma tumor antigen, Gp200/GCTM-2, is podocalyxin. Biochem Biophys Res Commun. 2003 Jan 10; 300(2):285-90.
    View in: PubMed
  36. San Francisco IF, DeWolf WC, Rosen S, Upton M, Olumi AF. Extended prostate needle biopsy improves concordance of Gleason grading between prostate needle biopsy and radical prostatectomy. J Urol. 2003 Jan; 169(1):136-40.
    View in: PubMed
  37. Ung JO, San Francisco IF, Regan MM, DeWolf WC, Olumi AF. The relationship of prostate gland volume to extended needle biopsy on prostate cancer detection. J Urol. 2003 Jan; 169(1):130-5.
    View in: PubMed
  38. Zhang PL, Rosen S, Veeramachaneni R, Kao J, DeWolf WC, Bubley G. Association between prostate cancer and serum testosterone levels. Prostate. 2002 Nov 1; 53(3):179-82.
    View in: PubMed
  39. Bubley GJ, Balk SP, Regan MM, Duggan S, Morrissey ME, Dewolf WC, Salgami E, Mantzoros C. Serum levels of insulin-like growth factor-1 and insulin-like growth factor-1 binding proteins after radical prostatectomy. J Urol. 2002 Nov; 168(5):2249-52.
    View in: PubMed
  40. Yoon JH, Dewolf WC. Decreasing prostate specific antigen value leading to the diagnosis of a pituitary adenoma. J Urol. 2002 Jul; 168(1):194.
    View in: PubMed
  41. Kerfoot BP, DeWolf WC. Does the outpatient setting provide the best environment for medical student learning of urology? J Urol. 2002 Apr; 167(4):1797-9.
    View in: PubMed
  42. Yin Y, Stahl BC, DeWolf WC, Morgentaler A. P53 and Fas are sequential mechanisms of testicular germ cell apoptosis. J Androl. 2002 Jan-Feb; 23(1):64-70.
    View in: PubMed
  43. Gollob JA, Upton MP, DeWolf WC, Atkins MB. Long-term remission in a patient with metastatic collecting duct carcinoma treated with taxol/carboplatin and surgery. Urology. 2001 Dec; 58(6):1058.
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  44. Santis WF, Hoffman MA, Dewolf WC. Early catheter removal in 100 consecutive patients undergoing radical retropubic prostatectomy. BJU Int. 2000 Jun; 85(9):1067-8.
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  45. Hoffman MA, DeWolf WC, Morgentaler A. Is low serum free testosterone a marker for high grade prostate cancer? J Urol. 2000 Mar; 163(3):824-7.
    View in: PubMed
  46. Maranchie JK, Bouyounes BT, Zhang PL, O'Donnell MA, Summerhayes IC, DeWolf WC. Clinical and pathological characteristics of micropapillary transitional cell carcinoma: a highly aggressive variant. J Urol. 2000 Mar; 163(3):748-51.
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  47. Luo Y, Chen X, Han R, Chorev M, Dewolf WC, O'Donnell MA. Mutated ras p21 as a target for cancer therapy in mouse transitional cell carcinoma. J Urol. 1999 Oct; 162(4):1519-26.
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  48. Santis WF, Billings EJ, DeWolf WC. Metastatic merkel cell tumor to bladder presenting as an encroachment tumor with gross hematuria. Urology. 1999 Jul; 54(1):163.
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  49. Luo Y, Chen X, Downs TM, DeWolf WC, O'Donnell MA. IFN-alpha 2B enhances Th1 cytokine responses in bladder cancer patients receiving Mycobacterium bovis bacillus Calmette-Guérin immunotherapy. J Immunol. 1999 Feb 15; 162(4):2399-405.
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  50. Yin Y, Stahl BC, DeWolf WC, Morgentaler A. p53-mediated germ cell quality control in spermatogenesis. Dev Biol. 1998 Dec 1; 204(1):165-71.
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  51. Yin Y, Stahl BC, DeWolf WC, Morgentaler A. Heat-induced testicular apoptosis occurs independently of hormonal depletion. Apoptosis. 1998 Sep; 3(4):281-7.
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  52. Yin Y, DeWolf WC, Morgentaler A. Experimental cryptorchidism induces testicular germ cell apoptosis by p53-dependent and -independent pathways in mice. Biol Reprod. 1998 Feb; 58(2):492-6.
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  53. Joyce R, Fenton MA, Rode P, Constantine M, Gaynes L, Kolvenbag G, DeWolf W, Balk S, Taplin ME, Bubley GJ. High dose bicalutamide for androgen independent prostate cancer: effect of prior hormonal therapy. J Urol. 1998 Jan; 159(1):149-53.
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  54. Khoudary KP, DeWolf WC, Bruning CO, Morgentaler A. Immediate sexual rehabilitation by simultaneous placement of penile prosthesis in patients undergoing radical prostatectomy: initial results in 50 patients. Urology. 1997 Sep; 50(3):395-9.
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  55. Yin Y, DeWolf WC, Morgentaler A. p53 is associated with the nuclear envelope in mouse testis. Biochem Biophys Res Commun. 1997 Jun 27; 235(3):689-94.
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  56. Socher SA, Yin Y, Dewolf WC, Morgentaler A. Temperature-mediated germ cell loss in the testis is associated with altered expression of the cell-cycle regulator p53. J Urol. 1997 May; 157(5):1986-9.
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  57. Yin Y, Hawkins KL, DeWolf WC, Morgentaler A. Heat stress causes testicular germ cell apoptosis in adult mice. J Androl. 1997 Mar-Apr; 18(2):159-65.
    View in: PubMed
  58. Downs TM, Kibel AS, DeWolf WC. Primary lymphoma of the bladder: a unique cystoscopic appearance. Urology. 1997 Feb; 49(2):276-8.
    View in: PubMed
  59. Morgentaler A, Bruning CO, DeWolf WC. Occult prostate cancer in men with low serum testosterone levels. JAMA. 1996 Dec 18; 276(23):1904-6.
    View in: PubMed
  60. Kibel AS, Krithivas K, Shamel LB, Kantoff PW, DeWolf WC. Constitutive expression of high levels of prostate-specific antigen in the absence of prostate carcinoma. Urology. 1996 Nov; 48(5):741-6.
    View in: PubMed
  61. Luo Y, Szilvasi A, Chen X, DeWolf WC, O'Donnell MA. A novel method for monitoring Mycobacterium bovis BCG trafficking with recombinant BCG expressing green fluorescent protein. Clin Diagn Lab Immunol. 1996 Nov; 3(6):761-8.
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  62. Kibel AS, Downs TM, Bubley GJ, DeWolf WC. Squamous cell carcinoma of the renal pelvis with inferior vena caval extension. J Urol. 1996 Oct; 156(4):1436.
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  63. Socher SA, Dewolf WC, Morgentaler A. Ureteral pseudodiverticulosis: the case for the retrograde urogram. Urology. 1996 Jun; 47(6):924-7.
    View in: PubMed
  64. Grégoire M, Schopperle WM, DeWolf WC. Distinct glycoforms of a tumor specific glycoprotein, gp200, in human testis and testicular tumors. J Urol. 1995 Jul; 154(1):275-7.
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  65. O'Donnell MA, DeWolf WC. Bacillus Calmette-Guérin immunotherapy for superficial bladder cancer. New prospects for an old warhorse. Surg Oncol Clin N Am. 1995 Apr; 4(2):189-202.
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  66. Rubenstein SC, Green LS, Schopperle WM, DeWolf WC, Morgentaler A. Temperature-dependent expression of a 95 kD protein in rat testis. Andrologia. 1995 Mar-Apr; 27(2):107-13.
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  67. Seiden MV, Kantoff PW, Krithivas K, Propert K, Bryant M, Haltom E, Gaynes L, Kaplan I, Bubley G, DeWolf W, et al. Detection of circulating tumor cells in men with localized prostate cancer. J Clin Oncol. 1994 Dec; 12(12):2634-9.
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  68. Ho GT, Gardner H, Mostofi K, DeWolf WC, Loughlin KR, Morgentaler A. The effect of testicular nongerm cell tumors on local spermatogenesis. Fertil Steril. 1994 Jul; 62(1):162-6.
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  69. O'Donnell MA, Aldovini A, Duda RB, Yang H, Szilvasi A, Young RA, DeWolf WC. Recombinant Mycobacterium bovis BCG secreting functional interleukin-2 enhances gamma interferon production by splenocytes. Infect Immun. 1994 Jun; 62(6):2508-14.
    View in: PubMed
  70. Morgentaler A, DeWolf WC. A self-expanding prostatic stent for bladder outlet obstruction in high risk patients. J Urol. 1993 Nov; 150(5 Pt 2):1636-40.
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  71. Capelouto CC, DeWolf WC. Genital swelling secondary to leakage from continuous ambulatory peritoneal dialysis: computerized tomography diagnosis. J Urol. 1993 Jul; 150(1):196-8.
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  72. Docimo SG, Rukstalis DB, Rukstalis MR, Kang J, Cotton D, DeWolf WC. Candida epididymitis: newly recognized opportunistic epididymal infection. Urology. 1993 Mar; 41(3):280-2.
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  73. Gregoire M, Kantoff P, DeWolf WC. Synchronous adenocarcinoma and transitional cell carcinoma of the bladder associated with augmentation: case report and review of the literature. J Urol. 1993 Jan; 149(1):115-8.
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  74. Schopperle WM, Armant DR, DeWolf WC. Purification of a tumor-specific PNA-binding glycoprotein, gp200, from a human embryonal carcinoma cell line. Arch Biochem Biophys. 1992 Nov 1; 298(2):538-43.
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  75. Ho GT, Gardner H, DeWolf WC, Loughlin KR, Morgentaler A. Influence of testicular carcinoma on ipsilateral spermatogenesis. J Urol. 1992 Sep; 148(3):821-5.
    View in: PubMed
  76. Kritsas JJ, Schopperle WM, DeWolf WC, Morgentaler A. Rapid high resolution two-dimensional electrophoresis of human sperm proteins. Electrophoresis. 1992 Jul; 13(7):445-9.
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  77. Morgentaler A, Schopperle WM, Crocker RH, DeWolf WC. Protein differences between normal and oligospermic human sperm demonstrated by two-dimensional gel electrophoresis. Fertil Steril. 1990 Nov; 54(5):902-5.
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  78. Rukstalis DB, Bubley GJ, Donahue JP, Richie JP, Seidman JG, DeWolf WC. Regional loss of chromosome 6 in two urological malignancies. Cancer Res. 1989 Sep 15; 49(18):5087-90.
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  79. Docimo SG, Dewolf WC. High failure rate of indwelling ureteral stents in patients with extrinsic obstruction: experience at 2 institutions. J Urol. 1989 Aug; 142(2 Pt 1):277-9.
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  80. Rukstalis DB, DeWolf WC. Molecular biological concepts in the etiology of testicular and other urologic malignancies. Semin Urol. 1988 Aug; 6(3):161-70.
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  81. Levine LA, DeWolf WC. Aspiration and tetracycline sclerotherapy of hydroceles. J Urol. 1988 May; 139(5):959-60.
    View in: PubMed
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