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Renee Margossian, M.D.

TitleAssistant Professor of Pediatrics
InstitutionChildren's Hospital Boston
DepartmentPediatrics
AddressChildrens Hospital
Cardiology, Farley 2
300 Longwood Ave
Boston MA 02115
Phone617/355-6429

 Bibliographic 
 selected publications
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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  1. Webber SA, Lipshultz SE, Sleeper LA, Lu M, Wilkinson JD, Addonizio LJ, Canter CE, Colan SD, Everitt MD, Jefferies JL, Kantor PF, Lamour JM, Margossian R, Pahl E, Rusconi PG, Towbin JA. Outcomes of restrictive cardiomyopathy in childhood and the influence of phenotype: a report from the Pediatric Cardiomyopathy Registry. Circulation. 2012 Sep 4; 126(10):1237-44.
    View in: PubMed
  2. Williams RV, Travison T, Kaltman JR, Cecchin F, Colan SD, Idriss SF, Lu M, Margossian R, Reed JH, Silver ES, Stephenson EA, Vetter VL. Comparison of Fontan Survivors with and without Pacemakers: A Report from the Pediatric Heart Network Fontan Cross-sectional Study. Congenit Heart Dis. 2013 Jan; 8(1):32-9.
    View in: PubMed
  3. Colan SD, Shirali G, Margossian R, Gallagher D, Altmann K, Canter C, Chen S, Golding F, Radojewski E, Camitta M, Carboni M, Rychik J, Stylianou M, Tani LY, Selamet Tierney ES, Wang Y, Sleeper LA. The ventricular volume variability study of the Pediatric Heart Network: study design and impact of beat averaging and variable type on the reproducibility of echocardiographic measurements in children with chronic dilated cardiomyopathy. J Am Soc Echocardiogr. 2012 Aug; 25(8):842-854.e6.
    View in: PubMed
  4. Rhodes J, Margossian R, Sleeper LA, Barker P, Bradley TJ, Lu M, Fogel M, Harris MA, Lai WW, Powell AJ, Puchalski MD, Shirali G, Colan SD. Non-geometric echocardiographic indices of ventricular function in patients with a Fontan circulation. J Am Soc Echocardiogr. 2011 Nov; 24(11):1213-9.
    View in: PubMed
  5. Saleeb SF, Margossian R, Spencer CT, Alexander ME, Smoot LB, Dorfman AL, Bergersen L, Gauvreau K, Marx GR, Colan SD. Reproducibility of echocardiographic diagnosis of left ventricular noncompaction. J Am Soc Echocardiogr. 2012 Feb; 25(2):194-202.
    View in: PubMed
  6. Kaza AK, Colan SD, Jaggers J, Lu M, Atz AM, Sleeper LA, McCrindle BW, Lambert LM, Margossian R, Lacro RV, Richmond ME, Natarajan S, Minich LL. Surgical interventions for atrioventricular septal defect subtypes: the pediatric heart network experience. Ann Thorac Surg. 2011 Oct; 92(4):1468-75; discussion 1475.
    View in: PubMed
  7. Spencer CT, Byrne BJ, Bryant RM, Margossian R, Maisenbacher M, Breitenger P, Benni PB, Redfearn S, Marcus E, Cade WT. Impaired cardiac reserve and severely diminished skeletal muscle O2 utilization mediate exercise intolerance in Barth syndrome. Am J Physiol Heart Circ Physiol. 2011 Nov; 301(5):H2122-9.
    View in: PubMed
  8. Williams RV, Zak V, Ravishankar C, Altmann K, Anderson J, Atz AM, Dunbar-Masterson C, Ghanayem N, Lambert L, Lurito K, Medoff-Cooper B, Margossian R, Pemberton VL, Russell J, Stylianou M, Hsu D. Factors affecting growth in infants with single ventricle physiology: a report from the Pediatric Heart Network Infant Single Ventricle Trial. J Pediatr. 2011 Dec; 159(6):1017-22.e2.
    View in: PubMed
  9. Banka P, Sleeper LA, Atz AM, Cowley CG, Gallagher D, Gillespie MJ, Graham EM, Margossian R, McCrindle BW, Sang CJ, Williams IA, Newburger JW. Practice variability and outcomes of coil embolization of aortopulmonary collaterals before Fontan completion: a report from the Pediatric Heart Network Fontan Cross-Sectional Study. Am Heart J. 2011 Jul; 162(1):125-30.
    View in: PubMed
  10. Atz AM, Travison TG, McCrindle BW, Mahony L, Quartermain M, Williams RV, Breitbart RE, Lu M, Radojewski E, Margossian R, Covitz W, Gersony WM. Late status of Fontan patients with persistent surgical fenestration. J Am Coll Cardiol. 2011 Jun 14; 57(24):2437-43.
    View in: PubMed
  11. Friedman KG, Margossian R, Graham DA, Harrild DM, Emani SM, Wilkins-Haug LE, McElhinney DB, Tworetzky W. Postnatal left ventricular diastolic function after fetal aortic valvuloplasty. Am J Cardiol. 2011 Aug 15; 108(4):556-60.
    View in: PubMed
  12. Mital S, Chung WK, Colan SD, Sleeper LA, Manlhiot C, Arrington CB, Cnota JF, Graham EM, Mitchell ME, Goldmuntz E, Li JS, Levine JC, Lee TM, Margossian R, Hsu DT. Renin-angiotensin-aldosterone genotype influences ventricular remodeling in infants with single ventricle. Circulation. 2011 May 31; 123(21):2353-62.
    View in: PubMed
  13. Guinan EC, Hewett EK, Domaney NM, Margossian R. Outcome of hematopoietic stem cell transplant in children with congenital heart disease. Pediatr Transplant. 2011 Feb; 15(1):75-80.
    View in: PubMed
  14. Daly KP, Colan SD, Blume ED, Margossian R, Gauvreau K, Duncan C, Lehmann LE, Chen MH. Changes in echocardiographic measures of systolic and diastolic function in children 1 year after hematopoietic SCT. Bone Marrow Transplant. 2011 Dec; 46(12):1532-9.
    View in: PubMed
  15. Printz BF, Sleeper LA, Newburger JW, Minich LL, Bradley T, Cohen MS, Frank D, Li JS, Margossian R, Shirali G, Takahashi M, Colan SD. Noncoronary cardiac abnormalities are associated with coronary artery dilation and with laboratory inflammatory markers in acute Kawasaki disease. J Am Coll Cardiol. 2011 Jan 4; 57(1):86-92.
    View in: PubMed
  16. Margossian R, Lu M, Minich LL, Bradley TJ, Cohen MS, Li JS, Printz BF, Shirali GS, Sleeper LA, Newburger JW, Colan SD. Predictors of coronary artery visualization in Kawasaki disease. J Am Soc Echocardiogr. 2011 Jan; 24(1):53-9.
    View in: PubMed
  17. Atz AM, Hawkins JA, Lu M, Cohen MS, Colan SD, Jaggers J, Lacro RV, McCrindle BW, Margossian R, Mosca RS, Sleeper LA, Minich LL. Surgical management of complete atrioventricular septal defect: associations with surgical technique, age, and trisomy 21. J Thorac Cardiovasc Surg. 2011 Jun; 141(6):1371-9.
    View in: PubMed
  18. Cohen MS, Zak V, Atz AM, Printz BF, Pinto N, Lambert L, Pemberton V, Li JS, Margossian R, Dunbar-Masterson C, McCrindle BW. Anthropometric measures after Fontan procedure: implications for suboptimal functional outcome. Am Heart J. 2010 Dec; 160(6):1092-8, 1098.e1.
    View in: PubMed
  19. Anderson PA, Breitbart RE, McCrindle BW, Sleeper LA, Atz AM, Hsu DT, Lu M, Margossian R, Williams RV. The Fontan patient: inconsistencies in medication therapy across seven pediatric heart network centers. Pediatr Cardiol. 2010 Nov; 31(8):1219-28.
    View in: PubMed
  20. Foerster SR, Canter CE, Cinar A, Sleeper LA, Webber SA, Pahl E, Kantor PF, Alvarez JA, Colan SD, Jefferies JL, Lamour JM, Margossian R, Messere JE, Rusconi PG, Shaddy RE, Towbin JA, Wilkinson JD, Lipshultz SE. Ventricular remodeling and survival are more favorable for myocarditis than for idiopathic dilated cardiomyopathy in childhood: an outcomes study from the Pediatric Cardiomyopathy Registry. Circ Heart Fail. 2010 Nov; 3(6):689-97.
    View in: PubMed
  21. Stephenson EA, Lu M, Berul CI, Etheridge SP, Idriss SF, Margossian R, Reed JH, Prakash A, Sleeper LA, Vetter VL, Blaufox AD. Arrhythmias in a contemporary fontan cohort: prevalence and clinical associations in a multicenter cross-sectional study. J Am Coll Cardiol. 2010 Sep 7; 56(11):890-6.
    View in: PubMed
  22. Hsu DT, Zak V, Mahony L, Sleeper LA, Atz AM, Levine JC, Barker PC, Ravishankar C, McCrindle BW, Williams RV, Altmann K, Ghanayem NS, Margossian R, Chung WK, Border WL, Pearson GD, Stylianou MP, Mital S. Enalapril in infants with single ventricle: results of a multicenter randomized trial. Circulation. 2010 Jul 27; 122(4):333-40.
    View in: PubMed
  23. Beroukhim RS, Graham DA, Margossian R, Brown DW, Geva T, Colan SD. An echocardiographic model predicting severity of aortic regurgitation in congenital heart disease. Circ Cardiovasc Imaging. 2010 Sep; 3(5):542-9.
    View in: PubMed
  24. Minich LL, Atz AM, Colan SD, Sleeper LA, Mital S, Jaggers J, Margossian R, Prakash A, Li JS, Cohen MS, Lacro RV, Klein GL, Hawkins JA. Partial and transitional atrioventricular septal defect outcomes. Ann Thorac Surg. 2010 Feb; 89(2):530-6.
    View in: PubMed
  25. McCrindle BW, Zak V, Sleeper LA, Paridon SM, Colan SD, Geva T, Mahony L, Li JS, Breitbart RE, Margossian R, Williams RV, Gersony WM, Atz AM. Laboratory measures of exercise capacity and ventricular characteristics and function are weakly associated with functional health status after Fontan procedure. Circulation. 2010 Jan 5; 121(1):34-42.
    View in: PubMed
  26. Williams IA, Sleeper LA, Colan SD, Lu M, Stephenson EA, Newburger JW, Gersony WM, Cohen MS, Cnota JF, Atz AM, Williams RV, Margossian R, Powell AJ, Stylianou MP, Hsu DT. Functional state following the Fontan procedure. Cardiol Young. 2009 Aug; 19(4):320-30.
    View in: PubMed
  27. Margossian R, Schwartz ML, Prakash A, Wruck L, Colan SD, Atz AM, Bradley TJ, Fogel MA, Hurwitz LM, Marcus E, Powell AJ, Printz BF, Puchalski MD, Rychik J, Shirali G, Williams R, Yoo SJ, Geva T. Comparison of echocardiographic and cardiac magnetic resonance imaging measurements of functional single ventricular volumes, mass, and ejection fraction (from the Pediatric Heart Network Fontan Cross-Sectional Study). Am J Cardiol. 2009 Aug 1; 104(3):419-28.
    View in: PubMed
  28. Hsu DT, Mital S, Ravishankar C, Margossian R, Li JS, Sleeper LA, Williams RV, Levine JC, McCrindle BW, Atz AM, Servedio D, Mahony L. Rationale and design of a trial of angiotensin-converting enzyme inhibition in infants with single ventricle. Am Heart J. 2009 Jan; 157(1):37-45.
    View in: PubMed
  29. Leonardi B, Margossian R, Colan SD, Powell AJ. Relationship of magnetic resonance imaging estimation of myocardial iron to left ventricular systolic and diastolic function in thalassemia. JACC Cardiovasc Imaging. 2008 Sep; 1(5):572-8.
    View in: PubMed
  30. Paridon SM, Mitchell PD, Colan SD, Williams RV, Blaufox A, Li JS, Margossian R, Mital S, Russell J, Rhodes J. A cross-sectional study of exercise performance during the first 2 decades of life after the Fontan operation. J Am Coll Cardiol. 2008 Jul 8; 52(2):99-107.
    View in: PubMed
  31. Anderson PA, Sleeper LA, Mahony L, Colan SD, Atz AM, Breitbart RE, Gersony WM, Gallagher D, Geva T, Margossian R, McCrindle BW, Paridon S, Schwartz M, Stylianou M, Williams RV, Clark BJ. Contemporary outcomes after the Fontan procedure: a Pediatric Heart Network multicenter study. J Am Coll Cardiol. 2008 Jul 8; 52(2):85-98.
    View in: PubMed
  32. Margossian R. Contemporary management of pediatric heart failure. Expert Rev Cardiovasc Ther. 2008 Feb; 6(2):187-97.
    View in: PubMed
  33. Webster G, Margossian R, Alexander ME, Cecchin F, Triedman JK, Walsh EP, Berul CI. Impact of transvenous ventricular pacing leads on tricuspid regurgitation in pediatric and congenital heart disease patients. J Interv Card Electrophysiol. 2008 Jan; 21(1):65-8.
    View in: PubMed
  34. Ismee A Williams, Andrew M Atz, James F Cnota, Meryl S Cohen, Steven D Colan, Welton M Gersony, Minmin Lu, Renee E Margossian, Jane W Newburger, Andrew J Powell, Lynn A Sleeper, Elizabeth A Stephenson, Mario Stylianou, Richard V Williams, and Daphne T Hsu . Predictors of Functional Status following Fontan Palliation: Development of a Fontan Functional Score . Circulation. 2007; 116:479.
  35. Susan Foerster, Amy Carey, Lynn Sleeper, Paul Kantor, Jacqueline Lamour, Steven Lipshultz, Renee Margossian, Jane Messere, Elfriede Pahl, Paolo Rusconi, Robert Shaddy, Jeffrey Towbin, Steve Webber, Charles Canter . Comparative Analysis of Outcomes for Pediatric Patients with Biopsy-Proven Myocarditis, Physician-Diagnosed Myocarditis and Idiopathic Dilated Cardiomyopathy. Circulation. 2007; 116:565.
  36. Carolyn T Spencer, Randall M Bryant, Barry Byrne, Elisabeth Heal, Renee Margossian, and W. Todd Cade . Impaired Skeletal Muscle Oxygen Utilization Contributes to Exercise Intolerance in Barth Syndrome . Circulation. 2007; 116:615.
  37. Rhodes J, Margossian R, Darras BT, Colan SD, Jenkins KJ, Geva T, Powell AJ. Safety and efficacy of carvedilol therapy for patients with dilated cardiomyopathy secondary to muscular dystrophy. Pediatr Cardiol. 2008 Mar; 29(2):343-51.
    View in: PubMed
  38. Chen JM, Glickstein JS, Margossian R, Mercando ML, Hellenbrand WE, Mosca RS, Quaegebeur JM. Superior outcomes for repair in infants and neonates with tetralogy of Fallot with absent pulmonary valve syndrome. J Thorac Cardiovasc Surg. 2006 Nov; 132(5):1099-104.
    View in: PubMed
  39. Friehs I, Margossian RE, Moran AM, Cao-Danh H, Moses MA, del Nido PJ. Vascular endothelial growth factor delays onset of failure in pressure-overload hypertrophy through matrix metalloproteinase activation and angiogenesis. Basic Res Cardiol. 2006 May; 101(3):204-13.
    View in: PubMed
  40. Danhaive O, Margossian R, Geva T, Kourembanas S. Pulmonary hypertension and right ventricular dysfunction in growth-restricted, extremely low birth weight neonates. J Perinatol. 2005 Jul; 25(7):495-9.
    View in: PubMed
  41. Tworetzky W, McElhinney DB, Margossian R, Moon-Grady AJ, Sallee D, Goldmuntz E, van der Velde ME, Silverman NH, Allan LD. Association between cardiac tumors and tuberous sclerosis in the fetus and neonate. Am J Cardiol. 2003 Aug 15; 92(4):487-9.
    View in: PubMed
  42. Marcus EN, Munoz RA, Margossian R, Colan SD, Wessel DL. Echocardiographic assessment of the right ventricular response to hypertension in neonates on the basis of average-shaped contraction models. J Am Soc Echocardiogr. 2002 Oct; 15(10 Pt 2):1145-53.
    View in: PubMed
  43. Margossian RE, Solowiejczyk D, Bourlon F, Apfel H, Gersony WM, Hordof AJ, Quaegebeur J. Septation of the single ventricle: revisited. J Thorac Cardiovasc Surg. 2002 Sep; 124(3):442-7.
    View in: PubMed
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