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Keywords
Last Name
Institution

Laurie Hollis Glimcher, M.D.

TitleAdjunct Professor of Immunology and Infectious Diseases
InstitutionHarvard School of Public Health
DepartmentImmunology and Infectious Diseases
AddressHarvard School of Public Health
Bagnoud Bldg
651 Huntington Ave
Boston MA 02115
Phone617/432-0622
Fax617/432-0084
Other Positions
TitleProfessor of Medicine
InstitutionBrigham and Women's Hospital
DepartmentMedicine


 Mentoring 
 completed student projects
The role of NFATc1 in osteoclast differentiation
Full Time/Year Long, 09/01/06 - 08/15/07
Identification of compounds that augment or inhibit T-bet expression in Th1 cells
Summer, 05/29/07 - 08/31/07

 Bibliographic 
 selected publications
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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  1. Greenblatt MB, Ritter SY, Wright J, Tsang K, Hu D, Glimcher LH, Aliprantis AO. NFATc1 and NFATc2 repress spontaneous osteoarthritis. Proc Natl Acad Sci U S A. 2013 Dec 3; 110(49):19914-9.
    View in: PubMed
  2. Lazarevic V, Glimcher LH, Lord GM. T-bet: a bridge between innate and adaptive immunity. Nat Rev Immunol. 2013 Nov; 13(11):777-89.
    View in: PubMed
  3. Shim JH, Greenblatt MB, Zou W, Huang Z, Wein MN, Brady N, Hu D, Charron J, Brodkin HR, Petsko GA, Zaller D, Zhai B, Gygi S, Glimcher LH, Jones DC. Schnurri-3 regulates ERK downstream of WNT signaling in osteoblasts. J Clin Invest. 2013 Sep 3; 123(9):4010-22.
    View in: PubMed
  4. Zou W, Greenblatt MB, Brady N, Lotinun S, Zhai B, de Rivera H, Singh A, Sun J, Gygi SP, Baron R, Glimcher LH, Jones DC. The microtubule-associated protein DCAMKL1 regulates osteoblast function via repression of Runx2. J Exp Med. 2013 Aug 26; 210(9):1793-806.
    View in: PubMed
  5. Greenblatt MB, Shim JH, Glimcher LH. Mitogen-activated protein kinase pathways in osteoblasts. Annu Rev Cell Dev Biol. 2013 Oct 6; 29:63-79.
    View in: PubMed
  6. Cho JA, Lee AH, Platzer B, Cross BC, Gardner BM, De Luca H, Luong P, Harding HP, Glimcher LH, Walter P, Fiebiger E, Ron D, Kagan JC, Lencer WI. The Unfolded Protein Response Element IRE1a Senses Bacterial Proteins Invading the ER to Activate RIG-I and Innate Immune Signaling. Cell Host Microbe. 2013 May 15; 13(5):558-69.
    View in: PubMed
  7. Park TY, Kim SH, Shin YC, Lee NH, Lee RK, Shim JH, Glimcher LH, Mook-Jung I, Cheong E, Kim WK, Honda F, Morio T, Lim JS, Lee SK. Amelioration of neurodegenerative diseases by cell death-induced cytoplasmic delivery of humanin. J Control Release. 2013 Mar 28; 166(3):307-15.
    View in: PubMed
  8. So JS, Hur KY, Tarrio M, Ruda V, Frank-Kamenetsky M, Fitzgerald K, Koteliansky V, Lichtman AH, Iwawaki T, Glimcher LH, Lee AH. Silencing of lipid metabolism genes through IRE1a-mediated mRNA decay lowers plasma lipids in mice. Cell Metab. 2012 Oct 3; 16(4):487-99.
    View in: PubMed
  9. Ermann J, Glimcher LH. After GWAS: mice to the rescue? Curr Opin Immunol. 2012 Oct; 24(5):564-70.
    View in: PubMed
  10. Fu W, Ergun A, Lu T, Hill JA, Haxhinasto S, Fassett MS, Gazit R, Adoro S, Glimcher L, Chan S, Kastner P, Rossi D, Collins JJ, Mathis D, Benoist C. A multiply redundant genetic switch 'locks in' the transcriptional signature of regulatory T cells. Nat Immunol. 2012 Oct; 13(10):972-80.
    View in: PubMed
  11. Wein MN, Jones DC, Shim JH, Aliprantis AO, Sulyanto R, Lazarevic V, Poliachik SL, Gross TS, Glimcher LH. Control of bone resorption in mice by Schnurri-3. Proc Natl Acad Sci U S A. 2012 May 22; 109(21):8173-8.
    View in: PubMed
  12. Glimcher LH, Lindvall O, Aguirre V, Topalian SL, Musunuru K, Fauci AS. Translating research into therapies. Cell. 2012 Mar 16; 148(6):1077-8.
    View in: PubMed
  13. Vidal RL, Figueroa A, Court FA, Thielen P, Molina C, Wirth C, Caballero B, Kiffin R, Segura-Aguilar J, Cuervo AM, Glimcher LH, Hetz C. Targeting the UPR transcription factor XBP1 protects against Huntington's disease through the regulation of FoxO1 and autophagy. Hum Mol Genet. 2012 May 15; 21(10):2245-62.
    View in: PubMed
  14. Hu Y, Park KK, Yang L, Wei X, Yang Q, Cho KS, Thielen P, Lee AH, Cartoni R, Glimcher LH, Chen DF, He Z. Differential effects of unfolded protein response pathways on axon injury-induced death of retinal ganglion cells. Neuron. 2012 Feb 9; 73(3):445-52.
    View in: PubMed
  15. Hur KY, So JS, Ruda V, Frank-Kamenetsky M, Fitzgerald K, Koteliansky V, Iwawaki T, Glimcher LH, Lee AH. IRE1a activation protects mice against acetaminophen-induced hepatotoxicity. J Exp Med. 2012 Feb 13; 209(2):307-18.
    View in: PubMed
  16. Greenblatt MB, Sargent JL, Farina G, Tsang K, Lafyatis R, Glimcher LH, Whitfield ML, Aliprantis AO. Interspecies comparison of human and murine scleroderma reveals IL-13 and CCL2 as disease subset-specific targets. Am J Pathol. 2012 Mar; 180(3):1080-94.
    View in: PubMed
  17. Glimcher L. Breaking down barriers to clinical translation: an interview with Laurie Glimcher. Interview by Sarah Allan. Dis Model Mech. 2012 Jan; 5(1):6-8.
    View in: PubMed
  18. Wan L, Zou W, Gao D, Inuzuka H, Fukushima H, Berg AH, Drapp R, Shaik S, Hu D, Lester C, Eguren M, Malumbres M, Glimcher LH, Wei W. Cdh1 regulates osteoblast function through an APC/C-independent modulation of Smurf1. Mol Cell. 2011 Dec 9; 44(5):721-33.
    View in: PubMed
  19. Shim JH, Greenblatt MB, Singh A, Brady N, Hu D, Drapp R, Ogawa W, Kasuga M, Noda T, Yang SH, Lee SK, Rebel VI, Glimcher LH. Administration of BMP2/7 in utero partially reverses Rubinstein-Taybi syndrome-like skeletal defects induced by Pdk1 or Cbp mutations in mice. J Clin Invest. 2012 Jan 3; 122(1):91-106.
    View in: PubMed
  20. Johansen CT, Wang J, McIntyre AD, Martins RA, Ban MR, Lanktree MB, Huff MW, Péterfy M, Mehrabian M, Lusis AJ, Kathiresan S, Anand SS, Yusuf S, Lee AH, Glimcher LH, Cao H, Hegele RA. Excess of rare variants in non-genome-wide association study candidate genes in patients with hypertriglyceridemia. Circ Cardiovasc Genet. 2012 Feb 1; 5(1):66-72.
    View in: PubMed
  21. Jurczak MJ, Lee AH, Jornayvaz FR, Lee HY, Birkenfeld AL, Guigni BA, Kahn M, Samuel VT, Glimcher LH, Shulman GI. Dissociation of inositol-requiring enzyme (IRE1a)-mediated c-Jun N-terminal kinase activation from hepatic insulin resistance in conditional X-box-binding protein-1 (XBP1) knock-out mice. J Biol Chem. 2012 Jan 20; 287(4):2558-67.
    View in: PubMed
  22. Zou W, Greenblatt MB, Shim JH, Kant S, Zhai B, Lotinun S, Brady N, Hu DZ, Gygi SP, Baron R, Davis RJ, Jones D, Glimcher LH. MLK3 regulates bone development downstream of the faciogenital dysplasia protein FGD1 in mice. J Clin Invest. 2011 Nov; 121(11):4383-92.
    View in: PubMed
  23. Hetz C, Martinon F, Rodriguez D, Glimcher LH. The unfolded protein response: integrating stress signals through the stress sensor IRE1a. Physiol Rev. 2011 Oct; 91(4):1219-43.
    View in: PubMed
  24. Jones D, Glimcher LH, Aliprantis AO. Osteoimmunology at the nexus of arthritis, osteoporosis, cancer, and infection. J Clin Invest. 2011 Jul; 121(7):2534-42.
    View in: PubMed
  25. Hess DA, Humphrey SE, Ishibashi J, Damsz B, Lee AH, Glimcher LH, Konieczny SF. Extensive pancreas regeneration following acinar-specific disruption of Xbp1 in mice. Gastroenterology. 2011 Oct; 141(4):1463-72.
    View in: PubMed
  26. Lazarevic V, Glimcher LH. T-bet in disease. Nat Immunol. 2011 Jul; 12(7):597-606.
    View in: PubMed
  27. Lee JH, Giannikopoulos P, Duncan SA, Wang J, Johansen CT, Brown JD, Plutzky J, Hegele RA, Glimcher LH, Lee AH. The transcription factor cyclic AMP-responsive element-binding protein H regulates triglyceride metabolism. Nat Med. 2011 Jul; 17(7):812-5.
    View in: PubMed
  28. Lee AH, Heidtman K, Hotamisligil GS, Glimcher LH. Dual and opposing roles of the unfolded protein response regulated by IRE1alpha and XBP1 in proinsulin processing and insulin secretion. Proc Natl Acad Sci U S A. 2011 May 24; 108(21):8885-90.
    View in: PubMed
  29. Ermann J, Garrett WS, Kuchroo J, Rourida K, Glickman JN, Bleich A, Glimcher LH. Severity of innate immune-mediated colitis is controlled by the cytokine deficiency-induced colitis susceptibility-1 (Cdcs1) locus. Proc Natl Acad Sci U S A. 2011 Apr 26; 108(17):7137-41.
    View in: PubMed
  30. Staton TL, Lazarevic V, Jones DC, Lanser AJ, Takagi T, Ishii S, Glimcher LH. Dampening of death pathways by schnurri-2 is essential for T-cell development. Nature. 2011 Apr 7; 472(7341):105-9.
    View in: PubMed
  31. Hetz C, Glimcher LH. Protein homeostasis networks in physiology and disease. Curr Opin Cell Biol. 2011 Apr; 23(2):123-5.
    View in: PubMed
  32. Matus S, Glimcher LH, Hetz C. Protein folding stress in neurodegenerative diseases: a glimpse into the ER. Curr Opin Cell Biol. 2011 Apr; 23(2):239-52.
    View in: PubMed
  33. Glimcher LH, Martinon F, Modlin RL. Editorial overview. Curr Opin Immunol. 2011 Feb; 23(1):1-2.
    View in: PubMed
  34. Zou W, Chen X, Shim JH, Huang Z, Brady N, Hu D, Drapp R, Sigrist K, Glimcher LH, Jones D. The E3 ubiquitin ligase Wwp2 regulates craniofacial development through mono-ubiquitylation of Goosecoid. Nat Cell Biol. 2011 Jan; 13(1):59-65.
    View in: PubMed
  35. Lazarevic V, Chen X, Shim JH, Hwang ES, Jang E, Bolm AN, Oukka M, Kuchroo VK, Glimcher LH. T-bet represses T(H)17 differentiation by preventing Runx1-mediated activation of the gene encoding ROR?t. Nat Immunol. 2011 Jan; 12(1):96-104.
    View in: PubMed
  36. Martinon F, Glimcher LH. Regulation of innate immunity by signaling pathways emerging from the endoplasmic reticulum. Curr Opin Immunol. 2011 Feb; 23(1):35-40.
    View in: PubMed
  37. Huh WJ, Esen E, Geahlen JH, Bredemeyer AJ, Lee AH, Shi G, Konieczny SF, Glimcher LH, Mills JC. XBP1 controls maturation of gastric zymogenic cells by induction of MIST1 and expansion of the rough endoplasmic reticulum. Gastroenterology. 2010 Dec; 139(6):2038-49.
    View in: PubMed
  38. Veiga P, Gallini CA, Beal C, Michaud M, Delaney ML, DuBois A, Khlebnikov A, van Hylckama Vlieg JE, Punit S, Glickman JN, Onderdonk A, Glimcher LH, Garrett WS. Bifidobacterium animalis subsp. lactis fermented milk product reduces inflammation by altering a niche for colitogenic microbes. Proc Natl Acad Sci U S A. 2010 Oct 19; 107(42):18132-7.
    View in: PubMed
  39. Schramek D, Leibbrandt A, Sigl V, Kenner L, Pospisilik JA, Lee HJ, Hanada R, Joshi PA, Aliprantis A, Glimcher L, Pasparakis M, Khokha R, Ormandy CJ, Widschwendter M, Schett G, Penninger JM. Osteoclast differentiation factor RANKL controls development of progestin-driven mammary cancer. Nature. 2010 Nov 4; 468(7320):98-102.
    View in: PubMed
  40. Garrett WS, Gallini CA, Yatsunenko T, Michaud M, DuBois A, Delaney ML, Punit S, Karlsson M, Bry L, Glickman JN, Gordon JI, Onderdonk AB, Glimcher LH. Enterobacteriaceae act in concert with the gut microbiota to induce spontaneous and maternally transmitted colitis. Cell Host Microbe. 2010 Sep 16; 8(3):292-300.
    View in: PubMed
  41. Collins PL, Chang S, Henderson M, Soutto M, Davis GM, McLoed AG, Townsend MJ, Glimcher LH, Mortlock DP, Aune TM. Distal regions of the human IFNG locus direct cell type-specific expression. J Immunol. 2010 Aug 1; 185(3):1492-501.
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  42. Greenblatt MB, Shim JH, Zou W, Sitara D, Schweitzer M, Hu D, Lotinun S, Sano Y, Baron R, Park JM, Arthur S, Xie M, Schneider MD, Zhai B, Gygi S, Davis R, Glimcher LH. The p38 MAPK pathway is essential for skeletogenesis and bone homeostasis in mice. J Clin Invest. 2010 Jul; 120(7):2457-73.
    View in: PubMed
  43. Greenblatt MB, Aliprantis A, Hu B, Glimcher LH. Calcineurin regulates innate antifungal immunity in neutrophils. J Exp Med. 2010 May 10; 207(5):923-31.
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  44. Jones DC, Schweitzer MN, Wein M, Sigrist K, Takagi T, Ishii S, Glimcher LH. Uncoupling of growth plate maturation and bone formation in mice lacking both Schnurri-2 and Schnurri-3. Proc Natl Acad Sci U S A. 2010 May 4; 107(18):8254-8.
    View in: PubMed
  45. Glimcher L. Laurie Glimcher: merging cell biology and immune function by Sedwick Caitlin. J Cell Biol. 2010 Apr 19; 189(2):192-3.
    View in: PubMed
  46. Martinon F, Chen X, Lee AH, Glimcher LH. TLR activation of the transcription factor XBP1 regulates innate immune responses in macrophages. Nat Immunol. 2010 May; 11(5):411-8.
    View in: PubMed
  47. Garrett WS, Gordon JI, Glimcher LH. Homeostasis and inflammation in the intestine. Cell. 2010 Mar 19; 140(6):859-70.
    View in: PubMed
  48. Greenblatt MB, Shim JH, Glimcher LH. TAK1 mediates BMP signaling in cartilage. Ann N Y Acad Sci. 2010 Mar; 1192:385-90.
    View in: PubMed
  49. Anderson AC, Lord GM, Dardalhon V, Lee DH, Sabatos-Peyton CA, Glimcher LH, Kuchroo VK. T-bet, a Th1 transcription factor regulates the expression of Tim-3. Eur J Immunol. 2010 Mar; 40(3):859-66.
    View in: PubMed
  50. Fathman JW, Gurish MF, Hemmers S, Bonham K, Friend DS, Grusby MJ, Glimcher LH, Mowen KA. NIP45 controls the magnitude of the type 2 T helper cell response. Proc Natl Acad Sci U S A. 2010 Feb 23; 107(8):3663-8.
    View in: PubMed
  51. Riol-Blanco L, Lazarevic V, Awasthi A, Mitsdoerffer M, Wilson BS, Croxford A, Waisman A, Kuchroo VK, Glimcher LH, Oukka M. IL-23 receptor regulates unconventional IL-17-producing T cells that control bacterial infections. J Immunol. 2010 Feb 15; 184(4):1710-20.
    View in: PubMed
  52. Jones DC, Glimcher LH. Regulation of bone formation and immune cell development by Schnurri proteins. Adv Exp Med Biol. 2010; 658:117-22.
    View in: PubMed
  53. Aliprantis AO, Glimcher LH. NFATc1 in inflammatory and musculoskeletal conditions. Adv Exp Med Biol. 2010; 658:69-75.
    View in: PubMed
  54. Glimcher LH. XBP1: the last two decades. Ann Rheum Dis. 2010 Jan; 69 Suppl 1:i67-71.
    View in: PubMed
  55. Matus S, Nassif M, Glimcher LH, Hetz C. XBP-1 deficiency in the nervous system reveals a homeostatic switch to activate autophagy. Autophagy. 2009 Nov; 5(8):1226-8.
    View in: PubMed
  56. Jenner RG, Townsend MJ, Jackson I, Sun K, Bouwman RD, Young RA, Glimcher LH, Lord GM. The transcription factors T-bet and GATA-3 control alternative pathways of T-cell differentiation through a shared set of target genes. Proc Natl Acad Sci U S A. 2009 Oct 20; 106(42):17876-81.
    View in: PubMed
  57. Glimcher LH. Reflections on health care. J Clin Invest. 2009 Oct; 119(10):2858-9.
    View in: PubMed
  58. Hetz C, Thielen P, Matus S, Nassif M, Court F, Kiffin R, Martinez G, Cuervo AM, Brown RH, Glimcher LH. XBP-1 deficiency in the nervous system protects against amyotrophic lateral sclerosis by increasing autophagy. Genes Dev. 2009 Oct 1; 23(19):2294-306.
    View in: PubMed
  59. Todd DJ, McHeyzer-Williams LJ, Kowal C, Lee AH, Volpe BT, Diamond B, McHeyzer-Williams MG, Glimcher LH. XBP1 governs late events in plasma cell differentiation and is not required for antigen-specific memory B cell development. J Exp Med. 2009 Sep 28; 206(10):2151-9.
    View in: PubMed
  60. Hetz C, Glimcher LH. Fine-tuning of the unfolded protein response: Assembling the IRE1alpha interactome. Mol Cell. 2009 Sep 11; 35(5):551-61.
    View in: PubMed
  61. Garrett WS, Punit S, Gallini CA, Michaud M, Zhang D, Sigrist KS, Lord GM, Glickman JN, Glimcher LH. Colitis-associated colorectal cancer driven by T-bet deficiency in dendritic cells. Cancer Cell. 2009 Sep 8; 16(3):208-19.
    View in: PubMed
  62. Glimcher LH, Lee AH. From sugar to fat: How the transcription factor XBP1 regulates hepatic lipogenesis. Ann N Y Acad Sci. 2009 Sep; 1173 Suppl 1:E2-9.
    View in: PubMed
  63. Garrett WS, Glimcher LH. T-bet-/- RAG2-/- ulcerative colitis: the role of T-bet as a peacekeeper of host-commensal relationships. Cytokine. 2009 Oct-Nov; 48(1-2):144-7.
    View in: PubMed
  64. Shim JH, Greenblatt MB, Xie M, Schneider MD, Zou W, Zhai B, Gygi S, Glimcher LH. TAK1 is an essential regulator of BMP signalling in cartilage. EMBO J. 2009 Jul 22; 28(14):2028-41.
    View in: PubMed
  65. Esensten JH, Lee MR, Glimcher LH, Bluestone JA. T-bet-deficient NOD mice are protected from diabetes due to defects in both T cell and innate immune system function. J Immunol. 2009 Jul 1; 183(1):75-82.
    View in: PubMed
  66. Yuan X, Ansari MJ, D'Addio F, Paez-Cortez J, Schmitt I, Donnarumma M, Boenisch O, Zhao X, Popoola J, Clarkson MR, Yagita H, Akiba H, Freeman GJ, Iacomini J, Turka LA, Glimcher LH, Sayegh MH. Targeting Tim-1 to overcome resistance to transplantation tolerance mediated by CD8 T17 cells. Proc Natl Acad Sci U S A. 2009 Jun 30; 106(26):10734-9.
    View in: PubMed
  67. Glimcher LH, Lieberman J. Harvard's women four years later. Nat Immunol. 2009 Jun; 10(6):559-61.
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  68. Lee AH, Glimcher LH. Intersection of the unfolded protein response and hepatic lipid metabolism. Cell Mol Life Sci. 2009 Sep; 66(17):2835-50.
    View in: PubMed
  69. Maldonado RA, Soriano MA, Perdomo LC, Sigrist K, Irvine DJ, Decker T, Glimcher LH. Control of T helper cell differentiation through cytokine receptor inclusion in the immunological synapse. J Exp Med. 2009 Apr 13; 206(4):877-92.
    View in: PubMed
  70. Lisbona F, Rojas-Rivera D, Thielen P, Zamorano S, Todd D, Martinon F, Glavic A, Kress C, Lin JH, Walter P, Reed JC, Glimcher LH, Hetz C. BAX inhibitor-1 is a negative regulator of the ER stress sensor IRE1alpha. Mol Cell. 2009 Mar 27; 33(6):679-91.
    View in: PubMed
  71. Lazarevic V, Zullo AJ, Schweitzer MN, Staton TL, Gallo EM, Crabtree GR, Glimcher LH. The gene encoding early growth response 2, a target of the transcription factor NFAT, is required for the development and maturation of natural killer T cells. Nat Immunol. 2009 Mar; 10(3):306-13.
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  72. Park JW, Min HJ, Sohn JH, Kim JY, Hong JH, Sigrist KS, Glimcher LH, Hwang ES. Restoration of T-box-containing protein expressed in T cells protects against allergen-induced asthma. J Allergy Clin Immunol. 2009 Feb; 123(2):479-85.
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  73. Yuan X, Paez-Cortez J, Schmitt-Knosalla I, D'Addio F, Mfarrej B, Donnarumma M, Habicht A, Clarkson MR, Iacomini J, Glimcher LH, Sayegh MH, Ansari MJ. A novel role of CD4 Th17 cells in mediating cardiac allograft rejection and vasculopathy. J Exp Med. 2008 Dec 22; 205(13):3133-44.
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  74. Wu J, Glimcher LH, Aliprantis AO. HCO3-/Cl- anion exchanger SLC4A2 is required for proper osteoclast differentiation and function. Proc Natl Acad Sci U S A. 2008 Nov 4; 105(44):16934-9.
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  75. Aliprantis AO, Ueki Y, Sulyanto R, Park A, Sigrist KS, Sharma SM, Ostrowski MC, Olsen BR, Glimcher LH. NFATc1 in mice represses osteoprotegerin during osteoclastogenesis and dissociates systemic osteopenia from inflammation in cherubism. J Clin Invest. 2008 Nov; 118(11):3775-89.
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  76. Kaser A, Lee AH, Franke A, Glickman JN, Zeissig S, Tilg H, Nieuwenhuis EE, Higgins DE, Schreiber S, Glimcher LH, Blumberg RS. XBP1 links ER stress to intestinal inflammation and confers genetic risk for human inflammatory bowel disease. Cell. 2008 Sep 5; 134(5):743-56.
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  77. Todd DJ, Lee AH, Glimcher LH. The endoplasmic reticulum stress response in immunity and autoimmunity. Nat Rev Immunol. 2008 Sep; 8(9):663-74.
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  78. Werneck MB, Lugo-Villarino G, Hwang ES, Cantor H, Glimcher LH. T-bet plays a key role in NK-mediated control of melanoma metastatic disease. J Immunol. 2008 Jun 15; 180(12):8004-10.
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  79. Lee AH, Scapa EF, Cohen DE, Glimcher LH. Regulation of hepatic lipogenesis by the transcription factor XBP1. Science. 2008 Jun 13; 320(5882):1492-6.
    View in: PubMed
  80. Tzianabos AO, Holsti MA, Zheng XX, Stucchi AF, Kuchroo VK, Strom TB, Glimcher LH, Cruikshank WW. Functional Th1 cells are required for surgical adhesion formation in a murine model. J Immunol. 2008 May 15; 180(10):6970-6.
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  81. Karwot R, Maxeiner JH, Schmitt S, Scholtes P, Hausding M, Lehr HA, Glimcher LH, Finotto S. Protective role of nuclear factor of activated T cells 2 in CD8+ long-lived memory T cells in an allergy model. J Allergy Clin Immunol. 2008 Apr; 121(4):992-9.e6.
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  82. Mukherjee S, Raje N, Schoonmaker JA, Liu JC, Hideshima T, Wein MN, Jones DC, Vallet S, Bouxsein ML, Pozzi S, Chhetri S, Seo YD, Aronson JP, Patel C, Fulciniti M, Purton LE, Glimcher LH, Lian JB, Stein G, Anderson KC, Scadden DT. Pharmacologic targeting of a stem/progenitor population in vivo is associated with enhanced bone regeneration in mice. J Clin Invest. 2008 Feb; 118(2):491-504.
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  83. Horsley V, Aliprantis AO, Polak L, Glimcher LH, Fuchs E. NFATc1 balances quiescence and proliferation of skin stem cells. Cell. 2008 Jan 25; 132(2):299-310.
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  84. Hetz C, Lee AH, Gonzalez-Romero D, Thielen P, Castilla J, Soto C, Glimcher LH. Unfolded protein response transcription factor XBP-1 does not influence prion replication or pathogenesis. Proc Natl Acad Sci U S A. 2008 Jan 15; 105(2):757-62.
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  85. Rengarajan J, Murphy E, Park A, Krone CL, Hett EC, Bloom BR, Glimcher LH, Rubin EJ. Mycobacterium tuberculosis Rv2224c modulates innate immune responses. Proc Natl Acad Sci U S A. 2008 Jan 8; 105(1):264-9.
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  86. Wein MN, Jones DC, Glimcher LH. Lentivirus delivery of shRNA constructs into osteoblasts. Methods Mol Biol. 2008; 455:149-55.
    View in: PubMed
  87. Hetz C, Glimcher L. The daily job of night killers: alternative roles of the BCL-2 family in organelle physiology. Trends Cell Biol. 2008 Jan; 18(1):38-44.
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  88. Glimcher LH, Jones DC, Wein MN. Control of postnatal bone mass by the zinc finger adapter protein Schnurri-3. Ann N Y Acad Sci. 2007 Nov; 1116:174-81.
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  89. Jones DC, Wein MN, Glimcher LH. Schnurri-3 is an essential regulator of osteoblast function and adult bone mass. Ann Rheum Dis. 2007 Nov; 66 Suppl 3:iii49-51.
    View in: PubMed
  90. Garrett WS, Lord GM, Punit S, Lugo-Villarino G, Mazmanian SK, Ito S, Glickman JN, Glimcher LH. Communicable ulcerative colitis induced by T-bet deficiency in the innate immune system. Cell. 2007 Oct 5; 131(1):33-45.
    View in: PubMed
  91. Iwakoshi NN, Pypaert M, Glimcher LH. The transcription factor XBP-1 is essential for the development and survival of dendritic cells. J Exp Med. 2007 Oct 1; 204(10):2267-75.
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  92. Hetz C, Thielen P, Fisher J, Pasinelli P, Brown RH, Korsmeyer S, Glimcher L. The proapoptotic BCL-2 family member BIM mediates motoneuron loss in a model of amyotrophic lateral sclerosis. Cell Death Differ. 2007 Jul; 14(7):1386-9.
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  93. Glimcher LH. Trawling for treasure: tales of T-bet. Nat Immunol. 2007 May; 8(5):448-50.
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  94. Erlebacher A, Vencato D, Price KA, Zhang D, Glimcher LH. Constraints in antigen presentation severely restrict T cell recognition of the allogeneic fetus. J Clin Invest. 2007 May; 117(5):1399-411.
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  95. Aliprantis AO, Wang J, Fathman JW, Lemaire R, Dorfman DM, Lafyatis R, Glimcher LH. Transcription factor T-bet regulates skin sclerosis through its function in innate immunity and via IL-13. Proc Natl Acad Sci U S A. 2007 Feb 20; 104(8):2827-30.
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  96. Alcaide P, Jones TG, Lord GM, Glimcher LH, Hallgren J, Arinobu Y, Akashi K, Paterson AM, Gurish MA, Luscinskas FW. Dendritic cell expression of the transcription factor T-bet regulates mast cell progenitor homing to mucosal tissue. J Exp Med. 2007 Feb 19; 204(2):431-9.
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  97. Jones DC, Wein MN, Glimcher LH. Schnurri-3: a key regulator of postnatal skeletal remodeling. Adv Exp Med Biol. 2007; 602:1-13.
    View in: PubMed
  98. Taqueti VR, Grabie N, Colvin R, Pang H, Jarolim P, Luster AD, Glimcher LH, Lichtman AH. T-bet controls pathogenicity of CTLs in the heart by separable effects on migration and effector activity. J Immunol. 2006 Nov 1; 177(9):5890-901.
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  99. Martinon F, Glimcher LH. Gout: new insights into an old disease. J Clin Invest. 2006 Aug; 116(8):2073-5.
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  100. Rosas LE, Snider HM, Barbi J, Satoskar AA, Lugo-Villarino G, Keiser T, Papenfuss T, Durbin JE, Radzioch D, Glimcher LH, Satoskar AR. Cutting edge: STAT1 and T-bet play distinct roles in determining outcome of visceral leishmaniasis caused by Leishmania donovani. J Immunol. 2006 Jul 1; 177(1):22-5.
    View in: PubMed
  101. Jones DC, Wein MN, Oukka M, Hofstaetter JG, Glimcher MJ, Glimcher LH. Regulation of adult bone mass by the zinc finger adapter protein Schnurri-3. Science. 2006 May 26; 312(5777):1223-7.
    View in: PubMed
  102. Hetz C, Bernasconi P, Fisher J, Lee AH, Bassik MC, Antonsson B, Brandt GS, Iwakoshi NN, Schinzel A, Glimcher LH, Korsmeyer SJ. Proapoptotic BAX and BAK modulate the unfolded protein response by a direct interaction with IRE1alpha. Science. 2006 Apr 28; 312(5773):572-6.
    View in: PubMed
  103. Shinohara ML, Lu L, Bu J, Werneck MB, Kobayashi KS, Glimcher LH, Cantor H. Osteopontin expression is essential for interferon-alpha production by plasmacytoid dendritic cells. Nat Immunol. 2006 May; 7(5):498-506.
    View in: PubMed
  104. Wang J, Fathman JW, Lugo-Villarino G, Scimone L, von Andrian U, Dorfman DM, Glimcher LH. Transcription factor T-bet regulates inflammatory arthritis through its function in dendritic cells. J Clin Invest. 2006 Feb; 116(2):414-21.
    View in: PubMed
  105. Lee AH, Chu GC, Iwakoshi NN, Glimcher LH. XBP-1 is required for biogenesis of cellular secretory machinery of exocrine glands. EMBO J. 2005 Dec 21; 24(24):4368-80.
    View in: PubMed
  106. Tirosh B, Iwakoshi NN, Glimcher LH, Ploegh HL. Rapid turnover of unspliced Xbp-1 as a factor that modulates the unfolded protein response. J Biol Chem. 2006 Mar 3; 281(9):5852-60.
    View in: PubMed
  107. Wein MN, Jones DC, Glimcher LH. Turning down the system: counter-regulatory mechanisms in bone and adaptive immunity. Immunol Rev. 2005 Dec; 208:66-79.
    View in: PubMed
  108. Shinohara ML, Jansson M, Hwang ES, Werneck MB, Glimcher LH, Cantor H. T-bet-dependent expression of osteopontin contributes to T cell polarization. Proc Natl Acad Sci U S A. 2005 Nov 22; 102(47):17101-6.
    View in: PubMed
  109. Hwang ES, Hong JH, Glimcher LH. IL-2 production in developing Th1 cells is regulated by heterodimerization of RelA and T-bet and requires T-bet serine residue 508. J Exp Med. 2005 Nov 7; 202(9):1289-300.
    View in: PubMed
  110. Ravindran R, Foley J, Stoklasek T, Glimcher LH, McSorley SJ. Expression of T-bet by CD4 T cells is essential for resistance to Salmonella infection. J Immunol. 2005 Oct 1; 175(7):4603-10.
    View in: PubMed
  111. Sullivan BM, Jobe O, Lazarevic V, Vasquez K, Bronson R, Glimcher LH, Kramnik I. Increased susceptibility of mice lacking T-bet to infection with Mycobacterium tuberculosis correlates with increased IL-10 and decreased IFN-gamma production. J Immunol. 2005 Oct 1; 175(7):4593-602.
    View in: PubMed
  112. Raby BA, Hwang ES, Van Steen K, Tantisira K, Peng S, Litonjua A, Lazarus R, Giallourakis C, Rioux JD, Sparrow D, Silverman EK, Glimcher LH, Weiss ST. T-bet polymorphisms are associated with asthma and airway hyperresponsiveness. Am J Respir Crit Care Med. 2006 Jan 1; 173(1):64-70.
    View in: PubMed
  113. Lugo-Villarino G, Ito S, Klinman DM, Glimcher LH. The adjuvant activity of CpG DNA requires T-bet expression in dendritic cells. Proc Natl Acad Sci U S A. 2005 Sep 13; 102(37):13248-53.
    View in: PubMed
  114. Tirosh B, Iwakoshi NN, Glimcher LH, Ploegh HL. XBP-1 specifically promotes IgM synthesis and secretion, but is dispensable for degradation of glycoproteins in primary B cells. J Exp Med. 2005 Aug 15; 202(4):505-16.
    View in: PubMed
  115. Lord GM, Rao RM, Choe H, Sullivan BM, Lichtman AH, Luscinskas FW, Glimcher LH. T-bet is required for optimal proinflammatory CD4+ T-cell trafficking. Blood. 2005 Nov 15; 106(10):3432-9.
    View in: PubMed
  116. Finotto S, Hausding M, Doganci A, Maxeiner JH, Lehr HA, Luft C, Galle PR, Glimcher LH. Asthmatic changes in mice lacking T-bet are mediated by IL-13. Int Immunol. 2005 Aug; 17(8):993-1007.
    View in: PubMed
  117. Tirosh B, Iwakoshi NN, Lilley BN, Lee AH, Glimcher LH, Ploegh HL. Human cytomegalovirus protein US11 provokes an unfolded protein response that may facilitate the degradation of class I major histocompatibility complex products. J Virol. 2005 Mar; 79(5):2768-79.
    View in: PubMed
  118. Hwang ES, Szabo SJ, Schwartzberg PL, Glimcher LH. T helper cell fate specified by kinase-mediated interaction of T-bet with GATA-3. Science. 2005 Jan 21; 307(5708):430-3.
    View in: PubMed
  119. Buono C, Binder CJ, Stavrakis G, Witztum JL, Glimcher LH, Lichtman AH. T-bet deficiency reduces atherosclerosis and alters plaque antigen-specific immune responses. Proc Natl Acad Sci U S A. 2005 Feb 1; 102(5):1596-601.
    View in: PubMed
  120. Dorfman DM, Hwang ES, Shahsafaei A, Glimcher LH. T-bet, a T cell-associated transcription factor, is expressed in Hodgkin's lymphoma. Hum Pathol. 2005 Jan; 36(1):10-5.
    View in: PubMed
  121. Tantisira KG, Hwang ES, Raby BA, Silverman ES, Lake SL, Richter BG, Peng SL, Drazen JM, Glimcher LH, Weiss ST. TBX21: a functional variant predicts improvement in asthma with the use of inhaled corticosteroids. Proc Natl Acad Sci U S A. 2004 Dec 28; 101(52):18099-104.
    View in: PubMed
  122. Mowen KA, Glimcher LH. Signaling pathways in Th2 development. Immunol Rev. 2004 Dec; 202:203-22.
    View in: PubMed
  123. Glimcher LH, Townsend MJ, Sullivan BM, Lord GM. Recent developments in the transcriptional regulation of cytolytic effector cells. Nat Rev Immunol. 2004 Nov; 4(11):900-11.
    View in: PubMed
  124. Erlebacher A, Price KA, Glimcher LH. Maintenance of mouse trophoblast stem cell proliferation by TGF-beta/activin. Dev Biol. 2004 Nov 1; 275(1):158-69.
    View in: PubMed
  125. Ozcan U, Cao Q, Yilmaz E, Lee AH, Iwakoshi NN, Ozdelen E, Tuncman G, Görgün C, Glimcher LH, Hotamisligil GS. Endoplasmic reticulum stress links obesity, insulin action, and type 2 diabetes. Science. 2004 Oct 15; 306(5695):457-61.
    View in: PubMed
  126. Maldonado RA, Irvine DJ, Schreiber R, Glimcher LH. A role for the immunological synapse in lineage commitment of CD4 lymphocytes. Nature. 2004 Sep 30; 431(7008):527-32.
    View in: PubMed
  127. Glimcher LH. How we can help the next generation of scientists: introducing The "Hands-On" Primary Caregiver's Support Program. J Immunol. 2004 Sep 1; 173(5):2891-2.
    View in: PubMed
  128. Romero-Ramirez L, Cao H, Nelson D, Hammond E, Lee AH, Yoshida H, Mori K, Glimcher LH, Denko NC, Giaccia AJ, Le QT, Koong AC. XBP1 is essential for survival under hypoxic conditions and is required for tumor growth. Cancer Res. 2004 Sep 1; 64(17):5943-7.
    View in: PubMed
  129. Mowen KA, Schurter BT, Fathman JW, David M, Glimcher LH. Arginine methylation of NIP45 modulates cytokine gene expression in effector T lymphocytes. Mol Cell. 2004 Aug 27; 15(4):559-71.
    View in: PubMed
  130. Dorfman DM, Hwang ES, Shahsafaei A, Glimcher LH. T-bet, a T-cell-associated transcription factor, is expressed in a subset of B-cell lymphoproliferative disorders. Am J Clin Pathol. 2004 Aug; 122(2):292-7.
    View in: PubMed
  131. Bettelli E, Sullivan B, Szabo SJ, Sobel RA, Glimcher LH, Kuchroo VK. Loss of T-bet, but not STAT1, prevents the development of experimental autoimmune encephalomyelitis. J Exp Med. 2004 Jul 5; 200(1):79-87.
    View in: PubMed
  132. Shaffer AL, Shapiro-Shelef M, Iwakoshi NN, Lee AH, Qian SB, Zhao H, Yu X, Yang L, Tan BK, Rosenwald A, Hurt EM, Petroulakis E, Sonenberg N, Yewdell JW, Calame K, Glimcher LH, Staudt LM. XBP1, downstream of Blimp-1, expands the secretory apparatus and other organelles, and increases protein synthesis in plasma cell differentiation. Immunity. 2004 Jul; 21(1):81-93.
    View in: PubMed
  133. Erlebacher A, Zhang D, Parlow AF, Glimcher LH. Ovarian insufficiency and early pregnancy loss induced by activation of the innate immune system. J Clin Invest. 2004 Jul; 114(1):39-48.
    View in: PubMed
  134. Lametschwandtner G, Biedermann T, Schwärzler C, Günther C, Kund J, Fassl S, Hinteregger S, Carballido-Perrig N, Szabo SJ, Glimcher LH, Carballido JM. Sustained T-bet expression confers polarized human TH2 cells with TH1-like cytokine production and migratory capacities. J Allergy Clin Immunol. 2004 May; 113(5):987-94.
    View in: PubMed
  135. Juedes AE, Rodrigo E, Togher L, Glimcher LH, von Herrath MG. T-bet controls autoaggressive CD8 lymphocyte responses in type 1 diabetes. J Exp Med. 2004 Apr 19; 199(8):1153-62.
    View in: PubMed
  136. Gerth AJ, Lin L, Neurath MF, Glimcher LH, Peng SL. An innate cell-mediated, murine ulcerative colitis-like syndrome in the absence of nuclear factor of activated T cells. Gastroenterology. 2004 Apr; 126(4):1115-21.
    View in: PubMed
  137. Townsend MJ, Weinmann AS, Matsuda JL, Salomon R, Farnham PJ, Biron CA, Gapin L, Glimcher LH. T-bet regulates the terminal maturation and homeostasis of NK and Valpha14i NKT cells. Immunity. 2004 Apr; 20(4):477-94.
    View in: PubMed
  138. Peng SL, Townsend MJ, Hecht JL, White IA, Glimcher LH. T-bet regulates metastasis rate in a murine model of primary prostate cancer. Cancer Res. 2004 Jan 15; 64(2):452-5.
    View in: PubMed
  139. Oukka M, Wein MN, Glimcher LH. Schnurri-3 (KRC) interacts with c-Jun to regulate the IL-2 gene in T cells. J Exp Med. 2004 Jan 5; 199(1):15-24.
    View in: PubMed
  140. Sullivan BM, Juedes A, Szabo SJ, von Herrath M, Glimcher LH. Antigen-driven effector CD8 T cell function regulated by T-bet. Proc Natl Acad Sci U S A. 2003 Dec 23; 100(26):15818-23.
    View in: PubMed
  141. Pai SY, Truitt ML, Ting CN, Leiden JM, Glimcher LH, Ho IC. Critical roles for transcription factor GATA-3 in thymocyte development. Immunity. 2003 Dec; 19(6):863-75.
    View in: PubMed
  142. Dorfman DM, van den Elzen P, Weng AP, Shahsafaei A, Glimcher LH. Differential expression of T-bet, a T-box transcription factor required for Th1 T-cell development, in peripheral T-cell lymphomas. Am J Clin Pathol. 2003 Dec; 120(6):866-73.
    View in: PubMed
  143. Finotto S, Glimcher L. T cell directives for transcriptional regulation in asthma. Springer Semin Immunopathol. 2004 Feb; 25(3-4):281-94.
    View in: PubMed
  144. Lee AH, Iwakoshi NN, Glimcher LH. XBP-1 regulates a subset of endoplasmic reticulum resident chaperone genes in the unfolded protein response. Mol Cell Biol. 2003 Nov; 23(21):7448-59.
    View in: PubMed
  145. Melanitou E, Liu E, Miao D, Yu L, Glimcher LH, Eisenbarth G. Absence of the T-bet gene coding for the Th1-related transcription factor does not affect diabetes-associated phenotypes in Balb/c mice. Ann N Y Acad Sci. 2003 Nov; 1005:187-91.
    View in: PubMed
  146. MacLean HE, Kim JI, Glimcher MJ, Wang J, Kronenberg HM, Glimcher LH. Absence of transcription factor c-maf causes abnormal terminal differentiation of hypertrophic chondrocytes during endochondral bone development. Dev Biol. 2003 Oct 1; 262(1):51-63.
    View in: PubMed
  147. Iwakoshi NN, Lee AH, Glimcher LH. It's a good year for Blimp-1 (and plasma cells). Immunity. 2003 Oct; 19(4):466-8.
    View in: PubMed
  148. Lee AH, Iwakoshi NN, Anderson KC, Glimcher LH. Proteasome inhibitors disrupt the unfolded protein response in myeloma cells. Proc Natl Acad Sci U S A. 2003 Aug 19; 100(17):9946-51.
    View in: PubMed
  149. Iwakoshi NN, Lee AH, Glimcher LH. The X-box binding protein-1 transcription factor is required for plasma cell differentiation and the unfolded protein response. Immunol Rev. 2003 Aug; 194:29-38.
    View in: PubMed
  150. Lugo-Villarino G, Maldonado-Lopez R, Possemato R, Penaranda C, Glimcher LH. T-bet is required for optimal production of IFN-gamma and antigen-specific T cell activation by dendritic cells. Proc Natl Acad Sci U S A. 2003 Jun 24; 100(13):7749-54.
    View in: PubMed
  151. Lyon MF, Jamieson RV, Perveen R, Glenister PH, Griffiths R, Boyd Y, Glimcher LH, Favor J, Munier FL, Black GC. A dominant mutation within the DNA-binding domain of the bZIP transcription factor Maf causes murine cataract and results in selective alteration in DNA binding. Hum Mol Genet. 2003 Mar 15; 12(6):585-94.
    View in: PubMed
  152. Iwakoshi NN, Lee AH, Vallabhajosyula P, Otipoby KL, Rajewsky K, Glimcher LH. Plasma cell differentiation and the unfolded protein response intersect at the transcription factor XBP-1. Nat Immunol. 2003 Apr; 4(4):321-9.
    View in: PubMed
  153. Erlebacher A, Lukens AK, Glimcher LH. Intrinsic susceptibility of mouse trophoblasts to natural killer cell-mediated attack in vivo. Proc Natl Acad Sci U S A. 2002 Dec 24; 99(26):16940-5.
    View in: PubMed
  154. Avni O, Lee D, Macian F, Szabo SJ, Glimcher LH, Rao A. T(H) cell differentiation is accompanied by dynamic changes in histone acetylation of cytokine genes. Nat Immunol. 2002 Jul; 3(7):643-51.
    View in: PubMed
  155. Neurath MF, Finotto S, Glimcher LH. The role of Th1/Th2 polarization in mucosal immunity. Nat Med. 2002 Jun; 8(6):567-73.
    View in: PubMed
  156. Neurath MF, Weigmann B, Finotto S, Glickman J, Nieuwenhuis E, Iijima H, Mizoguchi A, Mizoguchi E, Mudter J, Galle PR, Bhan A, Autschbach F, Sullivan BM, Szabo SJ, Glimcher LH, Blumberg RS. The transcription factor T-bet regulates mucosal T cell activation in experimental colitis and Crohn's disease. J Exp Med. 2002 May 6; 195(9):1129-43.
    View in: PubMed
  157. Peng SL, Szabo SJ, Glimcher LH. T-bet regulates IgG class switching and pathogenic autoantibody production. Proc Natl Acad Sci U S A. 2002 Apr 16; 99(8):5545-50.
    View in: PubMed
  158. Rengarajan J, Mowen KA, McBride KD, Smith ED, Singh H, Glimcher LH. Interferon regulatory factor 4 (IRF4) interacts with NFATc2 to modulate interleukin 4 gene expression. J Exp Med. 2002 Apr 15; 195(8):1003-12.
    View in: PubMed
  159. Ho IC, Glimcher LH. Transcription: tantalizing times for T cells. Cell. 2002 Apr; 109 Suppl:S109-20.
    View in: PubMed
  160. Yin Z, Chen C, Szabo SJ, Glimcher LH, Ray A, Craft J. T-Bet expression and failure of GATA-3 cross-regulation lead to default production of IFN-gamma by gammadelta T cells. J Immunol. 2002 Feb 15; 168(4):1566-71.
    View in: PubMed
  161. Finotto S, Neurath MF, Glickman JN, Qin S, Lehr HA, Green FH, Ackerman K, Haley K, Galle PR, Szabo SJ, Drazen JM, De Sanctis GT, Glimcher LH. Development of spontaneous airway changes consistent with human asthma in mice lacking T-bet. Science. 2002 Jan 11; 295(5553):336-8.
    View in: PubMed
  162. Szabo SJ, Sullivan BM, Stemmann C, Satoskar AR, Sleckman BP, Glimcher LH. Distinct effects of T-bet in TH1 lineage commitment and IFN-gamma production in CD4 and CD8 T cells. Science. 2002 Jan 11; 295(5553):338-42.
    View in: PubMed
  163. Oukka M, Kim ST, Lugo G, Sun J, Wu LC, Glimcher LH. A mammalian homolog of Drosophila schnurri, KRC, regulates TNF receptor-driven responses and interacts with TRAF2. Mol Cell. 2002 Jan; 9(1):121-31.
    View in: PubMed
  164. Szabo SJ, Sullivan BM, Peng SL, Glimcher LH. Molecular mechanisms regulating Th1 immune responses. Annu Rev Immunol. 2003; 21:713-58.
    View in: PubMed
  165. Rengarajan J, Tang B, Glimcher LH. NFATc2 and NFATc3 regulate T(H)2 differentiation and modulate TCR-responsiveness of naïve T(H)cells. Nat Immunol. 2002 Jan; 3(1):48-54.
    View in: PubMed
  166. Glimcher LH. Lineage commitment in lymphocytes: controlling the immune response. J Clin Invest. 2001 Oct; 108(7):s25-s30.
    View in: PubMed
  167. Reimold AM, Iwakoshi NN, Manis J, Vallabhajosyula P, Szomolanyi-Tsuda E, Gravallese EM, Friend D, Grusby MJ, Alt F, Glimcher LH. Plasma cell differentiation requires the transcription factor XBP-1. Nature. 2001 Jul 19; 412(6844):300-7.
    View in: PubMed
  168. Lieberson R, Mowen KA, McBride KD, Leautaud V, Zhang X, Suh WK, Wu L, Glimcher LH. Tumor necrosis factor receptor-associated factor (TRAF)2 represses the T helper cell type 2 response through interaction with NFAT-interacting protein (NIP45). J Exp Med. 2001 Jul 2; 194(1):89-98.
    View in: PubMed
  169. Ho IC, Arm JP, Bingham CO, Choi A, Austen KF, Glimcher LH. A novel group of phospholipase A2s preferentially expressed in type 2 helper T cells. J Biol Chem. 2001 May 25; 276(21):18321-6.
    View in: PubMed
  170. Reimold AM, Kim J, Finberg R, Glimcher LH. Decreased immediate inflammatory gene induction in activating transcription factor-2 mutant mice. Int Immunol. 2001 Feb; 13(2):241-8.
    View in: PubMed
  171. Pauza ME, Nguyen A, Wolfe T, Ho IC, Glimcher LH, von Herrath M, Lo D. Variable effects of transgenic c-Maf on autoimmune diabetes. Diabetes. 2001 Jan; 50(1):39-46.
    View in: PubMed
  172. Peng SL, Gerth AJ, Ranger AM, Glimcher LH. NFATc1 and NFATc2 together control both T and B cell activation and differentiation. Immunity. 2001 Jan; 14(1):13-20.
    View in: PubMed
  173. Rengarajan J, Szabo SJ, Glimcher LH. Transcriptional regulation of Th1/Th2 polarization. Immunol Today. 2000 Oct; 21(10):479-83.
    View in: PubMed
  174. Tsai EY, Falvo JV, Tsytsykova AV, Barczak AK, Reimold AM, Glimcher LH, Fenton MJ, Gordon DC, Dunn IF, Goldfeld AE. A lipopolysaccharide-specific enhancer complex involving Ets, Elk-1, Sp1, and CREB binding protein and p300 is recruited to the tumor necrosis factor alpha promoter in vivo. Mol Cell Biol. 2000 Aug; 20(16):6084-94.
    View in: PubMed
  175. Glimcher LH, Murphy KM. Lineage commitment in the immune system: the T helper lymphocyte grows up. Genes Dev. 2000 Jul 15; 14(14):1693-711.
    View in: PubMed
  176. Szabo SJ, Kim ST, Costa GL, Zhang X, Fathman CG, Glimcher LH. A novel transcription factor, T-bet, directs Th1 lineage commitment. Cell. 2000 Mar 17; 100(6):655-69.
    View in: PubMed
  177. Rengarajan J, Mittelstadt PR, Mages HW, Gerth AJ, Kroczek RA, Ashwell JD, Glimcher LH. Sequential involvement of NFAT and Egr transcription factors in FasL regulation. Immunity. 2000 Mar; 12(3):293-300.
    View in: PubMed
  178. Reimold AM, Etkin A, Clauss I, Perkins A, Friend DS, Zhang J, Horton HF, Scott A, Orkin SH, Byrne MC, Grusby MJ, Glimcher LH. An essential role in liver development for transcription factor XBP-1. Genes Dev. 2000 Jan 15; 14(2):152-7.
    View in: PubMed
  179. Ranger AM, Gerstenfeld LC, Wang J, Kon T, Bae H, Gravallese EM, Glimcher MJ, Glimcher LH. The nuclear factor of activated T cells (NFAT) transcription factor NFATp (NFATc2) is a repressor of chondrogenesis. J Exp Med. 2000 Jan 3; 191(1):9-22.
    View in: PubMed
  180. de Bont ES, Reilly CR, Lo D, Glimcher LH, Laufer TM. A minimal level of MHC class II expression is sufficient to abrogate autoreactivity. Int Immunol. 1999 Aug; 11(8):1295-306.
    View in: PubMed
  181. Wen XY, Stewart AK, Sooknanan RR, Henderson G, Hawley TS, Reimold AM, Glimcher LH, Baumann H, Malek LT, Hawley RG. Identification of c-myc promoter-binding protein and X-box binding protein 1 as interleukin-6 target genes in human multiple myeloma cells. Int J Oncol. 1999 Jul; 15(1):173-8.
    View in: PubMed
  182. Maekawa T, Bernier F, Sato M, Nomura S, Singh M, Inoue Y, Tokunaga T, Imai H, Yokoyama M, Reimold A, Glimcher LH, Ishii S. Mouse ATF-2 null mutants display features of a severe type of meconium aspiration syndrome. J Biol Chem. 1999 Jun 18; 274(25):17813-9.
    View in: PubMed
  183. Kim JI, Ho IC, Grusby MJ, Glimcher LH. The transcription factor c-Maf controls the production of interleukin-4 but not other Th2 cytokines. Immunity. 1999 Jun; 10(6):745-51.
    View in: PubMed
  184. Laufer TM, Fan L, Glimcher LH. Self-reactive T cells selected on thymic cortical epithelium are polyclonal and are pathogenic in vivo. J Immunol. 1999 May 1; 162(9):5078-84.
    View in: PubMed
  185. Kim JI, Li T, Ho IC, Grusby MJ, Glimcher LH. Requirement for the c-Maf transcription factor in crystallin gene regulation and lens development. Proc Natl Acad Sci U S A. 1999 Mar 30; 96(7):3781-5.
    View in: PubMed
  186. Laufer TM, Glimcher LH, Lo D. Using thymus anatomy to dissect T cell repertoire selection. Semin Immunol. 1999 Feb; 11(1):65-70.
    View in: PubMed
  187. Ho IC, Kaplan MH, Jackson-Grusby L, Glimcher LH, Grusby MJ. Marking IL-4-producing cells by knock-in of the IL-4 gene. Int Immunol. 1999 Feb; 11(2):243-7.
    View in: PubMed
  188. Glimcher LH, Singh H. Transcription factors in lymphocyte development--T and B cells get together. Cell. 1999 Jan 8; 96(1):13-23.
    View in: PubMed
  189. Ho IC, Kim JI, Szabo SJ, Glimcher LH. Tissue-specific regulation of cytokine gene expression. Cold Spring Harb Symp Quant Biol. 1999; 64:573-84.
    View in: PubMed
  190. Ho IC, Kim JH, Rooney JW, Spiegelman BM, Glimcher LH. A potential role for the nuclear factor of activated T cells family of transcriptional regulatory proteins in adipogenesis. Proc Natl Acad Sci U S A. 1998 Dec 22; 95(26):15537-41.
    View in: PubMed
  191. Ho IC, Lo D, Glimcher LH. c-maf promotes T helper cell type 2 (Th2) and attenuates Th1 differentiation by both interleukin 4-dependent and -independent mechanisms. J Exp Med. 1998 Nov 16; 188(10):1859-66.
    View in: PubMed
  192. Ranger AM, Oukka M, Rengarajan J, Glimcher LH. Inhibitory function of two NFAT family members in lymphoid homeostasis and Th2 development. Immunity. 1998 Nov; 9(5):627-35.
    View in: PubMed
  193. Oukka M, Ho IC, de la Brousse FC, Hoey T, Grusby MJ, Glimcher LH. The transcription factor NFAT4 is involved in the generation and survival of T cells. Immunity. 1998 Sep; 9(3):295-304.
    View in: PubMed
  194. Ranger AM, Grusby MJ, Hodge MR, Gravallese EM, de la Brousse FC, Hoey T, Mickanin C, Baldwin HS, Glimcher LH. The transcription factor NF-ATc is essential for cardiac valve formation. Nature. 1998 Mar 12; 392(6672):186-90.
    View in: PubMed
  195. Sabatine MS, Laufer T, Glimcher LH, Widmer M, Winn H, Auchincloss H. Delayed rejection of soluble tumor necrosis factor receptor-secreting tumor allografts. Transplantation. 1998 Jan 15; 65(1):113-20.
    View in: PubMed
  196. Ranger AM, Hodge MR, Gravallese EM, Oukka M, Davidson L, Alt FW, de la Brousse FC, Hoey T, Grusby M, Glimcher LH. Delayed lymphoid repopulation with defects in IL-4-driven responses produced by inactivation of NF-ATc. Immunity. 1998 Jan; 8(1):125-34.
    View in: PubMed
  197. Laufer TM, Smiley ST, Ranger A, Clements VK, Ostrand-Rosenberg S, Glimcher LH. Single amino acid mutations in the murine MHC class II A beta cytoplasmic domain abrogate antigen presentation. J Immunol. 1997 Dec 15; 159(12):5914-20.
    View in: PubMed
  198. Szabo SJ, Glimcher LH, Ho IC. Genes that regulate interleukin-4 expression in T cells. Curr Opin Immunol. 1997 Dec; 9(6):776-81.
    View in: PubMed
  199. Douhan J, Lieberson R, Knoll JH, Zhou H, Glimcher LH. An isotype-specific activator of major histocompatibility complex (MHC) class II genes that is independent of class II transactivator. J Exp Med. 1997 Jun 2; 185(11):1885-95.
    View in: PubMed
  200. Zhou H, Su HS, Zhang X, Douhan J, Glimcher LH. CIITA-dependent and -independent class II MHC expression revealed by a dominant negative mutant. J Immunol. 1997 May 15; 158(10):4741-9.
    View in: PubMed
  201. Lee RS, Grusby MJ, Laufer TM, Colvin R, Glimcher LH, Auchincloss H. CD8+ effector cells responding to residual class I antigens, with help from CD4+ cells stimulated indirectly, cause rejection of "major histocompatibility complex-deficient" skin grafts. Transplantation. 1997 Apr 27; 63(8):1123-33.
    View in: PubMed
  202. Lo D, Reilly CR, Burkly LC, DeKoning J, Laufer TM, Glimcher LH. Thymic stromal cell specialization and the T-cell receptor repertoire. Immunol Res. 1997 Feb; 16(1):3-14.
    View in: PubMed
  203. Hodge MR, Chun HJ, Rengarajan J, Alt A, Lieberson R, Glimcher LH. NF-AT-Driven interleukin-4 transcription potentiated by NIP45. Science. 1996 Dec 13; 274(5294):1903-5.
    View in: PubMed
  204. Brown JA, Titus RG, Nabavi N, Glimcher LH. Blockade of CD86 ameliorates Leishmania major infection by down-regulating the Th2 response. J Infect Dis. 1996 Dec; 174(6):1303-8.
    View in: PubMed
  205. Ranger AM, Das MP, Kuchroo VK, Glimcher LH. B7-2 (CD86) is essential for the development of IL-4-producing T cells. Int Immunol. 1996 Oct; 8(10):1549-60.
    View in: PubMed
  206. Laufer TM, DeKoning J, Markowitz JS, Lo D, Glimcher LH. Unopposed positive selection and autoreactivity in mice expressing class II MHC only on thymic cortex. Nature. 1996 Sep 5; 383(6595):81-5.
    View in: PubMed
  207. Ho IC, Hodge MR, Rooney JW, Glimcher LH. The proto-oncogene c-maf is responsible for tissue-specific expression of interleukin-4. Cell. 1996 Jun 28; 85(7):973-83.
    View in: PubMed
  208. Clauss IM, Chu M, Zhao JL, Glimcher LH. The basic domain/leucine zipper protein hXBP-1 preferentially binds to and transactivates CRE-like sequences containing an ACGT core. Nucleic Acids Res. 1996 May 15; 24(10):1855-64.
    View in: PubMed
  209. Baskar S, Clements VK, Glimcher LH, Nabavi N, Ostrand-Rosenberg S. Rejection of MHC class II-transfected tumor cells requires induction of tumor-encoded B7-1 and/or B7-2 costimulatory molecules. J Immunol. 1996 May 15; 156(10):3821-7.
    View in: PubMed
  210. Hodge MR, Ranger AM, Charles de la Brousse F, Hoey T, Grusby MJ, Glimcher LH. Hyperproliferation and dysregulation of IL-4 expression in NF-ATp-deficient mice. Immunity. 1996 Apr; 4(4):397-405.
    View in: PubMed
  211. Douhan J, Hauber I, Eibl MM, Glimcher LH. Genetic evidence for a new type of major histocompatibility complex class II combined immunodeficiency characterized by a dyscoordinate regulation of HLA-D alpha and beta chains. J Exp Med. 1996 Mar 1; 183(3):1063-9.
    View in: PubMed
  212. Zhao J, Freeman GJ, Gray GS, Nadler LM, Glimcher LH. A cell type-specific enhancer in the human B7.1 gene regulated by NF-kappaB. J Exp Med. 1996 Mar 1; 183(3):777-89.
    View in: PubMed
  213. Reimold AM, Ponath PD, Li YS, Hardy RR, David CS, Strominger JL, Glimcher LH. Transcription factor B cell lineage-specific activator protein regulates the gene for human X-box binding protein 1. J Exp Med. 1996 Feb 1; 183(2):393-401.
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  214. Douhan J, Brown JA, Gleit ZL, David CS, Glimcher LH. Regulation of the E beta gene in vivo: lessons from E beta d transgenic mice. Int Immunol. 1996 Feb; 8(2):255-65.
    View in: PubMed
  215. Steele DJ, Laufer TM, Smiley ST, Ando Y, Grusby MJ, Glimcher LH, Auchincloss H. Two levels of help for B cell alloantibody production. J Exp Med. 1996 Feb 1; 183(2):699-703.
    View in: PubMed
  216. Reimold AM, Grusby MJ, Kosaras B, Fries JW, Mori R, Maniwa S, Clauss IM, Collins T, Sidman RL, Glimcher MJ, Glimcher LH. Chondrodysplasia and neurological abnormalities in ATF-2-deficient mice. Nature. 1996 Jan 18; 379(6562):262-5.
    View in: PubMed
  217. Smiley ST, Rudensky AY, Glimcher LH, Grusby MJ. Truncation of the class II beta-chain cytoplasmic domain influences the level of class II/invariant chain-derived peptide complexes. Proc Natl Acad Sci U S A. 1996 Jan 9; 93(1):241-4.
    View in: PubMed
  218. Tarleton RL, Grusby MJ, Postan M, Glimcher LH. Trypanosoma cruzi infection in MHC-deficient mice: further evidence for the role of both class I- and class II-restricted T cells in immune resistance and disease. Int Immunol. 1996 Jan; 8(1):13-22.
    View in: PubMed
  219. Rooney JW, Sun YL, Glimcher LH, Hoey T. Novel NFAT sites that mediate activation of the interleukin-2 promoter in response to T-cell receptor stimulation. Mol Cell Biol. 1995 Nov; 15(11):6299-310.
    View in: PubMed
  220. Glimcher LH, Ivashkiv LB. Repression of Constitutive and Interferon-gamma-Induced Class II Major Histocompatibility Complex Genes by Cyclic AMP and Prostaglandins. Am J Ther. 1995 Sep; 2(9):676.
    View in: PubMed
  221. Hodge MR, Rooney JW, Glimcher LH. The proximal promoter of the IL-4 gene is composed of multiple essential regulatory sites that bind at least two distinct factors. J Immunol. 1995 Jun 15; 154(12):6397-405.
    View in: PubMed
  222. Rooney JW, Hoey T, Glimcher LH. Coordinate and cooperative roles for NF-AT and AP-1 in the regulation of the murine IL-4 gene. Immunity. 1995 May; 2(5):473-83.
    View in: PubMed
  223. Zhou H, Glimcher LH. Human MHC class II gene transcription directed by the carboxyl terminus of CIITA, one of the defective genes in type II MHC combined immune deficiency. Immunity. 1995 May; 2(5):545-53.
    View in: PubMed
  224. Chakkalath HR, Theodos CM, Markowitz JS, Grusby MJ, Glimcher LH, Titus RG. Class II major histocompatibility complex-deficient mice initially control an infection with Leishmania major but succumb to the disease. J Infect Dis. 1995 May; 171(5):1302-8.
    View in: PubMed
  225. Smiley ST, Laufer TM, Lo D, Glimcher LH, Grusby MJ. Transgenic mice expressing MHC class II molecules with truncated A beta cytoplasmic domains reveal signaling-independent defects in antigen presentation. Int Immunol. 1995 Apr; 7(4):665-77.
    View in: PubMed
  226. Kuchroo VK, Das MP, Brown JA, Ranger AM, Zamvil SS, Sobel RA, Weiner HL, Nabavi N, Glimcher LH. B7-1 and B7-2 costimulatory molecules activate differentially the Th1/Th2 developmental pathways: application to autoimmune disease therapy. Cell. 1995 Mar 10; 80(5):707-18.
    View in: PubMed
  227. Ruderman EM, Kerr JS, Telford SR, Spielman A, Glimcher LH, Gravallese EM. Early murine Lyme carditis has a macrophage predominance and is independent of major histocompatibility complex class II-CD4+ T cell interactions. J Infect Dis. 1995 Feb; 171(2):362-70.
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  228. Baskar S, Glimcher L, Nabavi N, Jones RT, Ostrand-Rosenberg S. Major histocompatibility complex class II+B7-1+ tumor cells are potent vaccines for stimulating tumor rejection in tumor-bearing mice. J Exp Med. 1995 Feb 1; 181(2):619-29.
    View in: PubMed
  229. Grusby MJ, Glimcher LH. Immune responses in MHC class II-deficient mice. Annu Rev Immunol. 1995; 13:417-35.
    View in: PubMed
  230. Avery AC, Markowitz JS, Grusby MJ, Glimcher LH, Cantor H. Activation of T cells by superantigen in class II-negative mice. J Immunol. 1994 Dec 1; 153(11):4853-61.
    View in: PubMed
  231. Gonzalez-Gay MA, Nabozny GH, Bull MJ, Zanelli E, Douhan J, Griffiths MM, Glimcher LH, Luthra HS, David CS. Protective role of major histocompatibility complex class II Ebd transgene on collagen-induced arthritis. J Exp Med. 1994 Oct 1; 180(4):1559-64.
    View in: PubMed
  232. Matsushima GK, Taniike M, Glimcher LH, Grusby MJ, Frelinger JA, Suzuki K, Ting JP. Absence of MHC class II molecules reduces CNS demyelination, microglial/macrophage infiltration, and twitching in murine globoid cell leukodystrophy. Cell. 1994 Aug 26; 78(4):645-56.
    View in: PubMed
  233. Darling JM, Glimcher LH, Shortkroff S, Albano B, Gravallese EM. Expression of metalloproteinases in pigmented villonodular synovitis. Hum Pathol. 1994 Aug; 25(8):825-30.
    View in: PubMed
  234. Mombaerts P, Mizoguchi E, Ljunggren HG, Iacomini J, Ishikawa H, Wang L, Grusby MJ, Glimcher LH, Winn HJ, Bhan AK, et al. Peripheral lymphoid development and function in TCR mutant mice. Int Immunol. 1994 Jul; 6(7):1061-70.
    View in: PubMed
  235. Linette GP, Grusby MJ, Hedrick SM, Hansen TH, Glimcher LH, Korsmeyer SJ. Bcl-2 is upregulated at the CD4+ CD8+ stage during positive selection and promotes thymocyte differentiation at several control points. Immunity. 1994 Jun; 1(3):197-205.
    View in: PubMed
  236. Degermann S, Surh CD, Glimcher LH, Sprent J, Lo D. B7 expression on thymic medullary epithelium correlates with epithelium-mediated deletion of V beta 5+ thymocytes. J Immunol. 1994 Apr 1; 152(7):3254-63.
    View in: PubMed
  237. Jevnikar AM, Grusby MJ, Glimcher LH. Prevention of nephritis in major histocompatibility complex class II-deficient MRL-lpr mice. J Exp Med. 1994 Apr 1; 179(4):1137-43.
    View in: PubMed
  238. Lee RS, Grusby MJ, Glimcher LH, Winn HJ, Auchincloss H. Indirect recognition by helper cells can induce donor-specific cytotoxic T lymphocytes in vivo. J Exp Med. 1994 Mar 1; 179(3):865-72.
    View in: PubMed
  239. Rooney JW, Hodge MR, McCaffrey PG, Rao A, Glimcher LH. A common factor regulates both Th1- and Th2-specific cytokine gene expression. EMBO J. 1994 Feb 1; 13(3):625-33.
    View in: PubMed
  240. Ivashkiv LB, Ayres A, Glimcher LH. Inhibition of IFN-gamma induction of class II MHC genes by cAMP and prostaglandins. Immunopharmacology. 1994 Jan-Feb; 27(1):67-77.
    View in: PubMed
  241. Lederer JA, Liou JS, Todd MD, Glimcher LH, Lichtman AH. Regulation of cytokine gene expression in T helper cell subsets. J Immunol. 1994 Jan 1; 152(1):77-86.
    View in: PubMed
  242. Crump AL, Grusby MJ, Glimcher LH, Cantor H. Thymocyte development in major histocompatibility complex-deficient mice: evidence for stochastic commitment to the CD4 and CD8 lineages. Proc Natl Acad Sci U S A. 1993 Nov 15; 90(22):10739-43.
    View in: PubMed
  243. Bigby M, Markowitz JS, Bleicher PA, Grusby MJ, Simha S, Siebrecht M, Wagner M, Nagler-Anderson C, Glimcher LH. Most gamma delta T cells develop normally in the absence of MHC class II molecules. J Immunol. 1993 Nov 1; 151(9):4465-75.
    View in: PubMed
  244. Wiest DL, Yuan L, Jefferson J, Benveniste P, Tsokos M, Klausner RD, Glimcher LH, Samelson LE, Singer A. Regulation of T cell receptor expression in immature CD4+CD8+ thymocytes by p56lck tyrosine kinase: basis for differential signaling by CD4 and CD8 in immature thymocytes expressing both coreceptor molecules. J Exp Med. 1993 Nov 1; 178(5):1701-12.
    View in: PubMed
  245. Mombaerts P, Mizoguchi E, Grusby MJ, Glimcher LH, Bhan AK, Tonegawa S. Spontaneous development of inflammatory bowel disease in T cell receptor mutant mice. Cell. 1993 Oct 22; 75(2):274-82.
    View in: PubMed
  246. Reimold AM, Kara CJ, Rooney JW, Glimcher LH. Transforming growth factor beta 1 repression of the HLA-DR alpha gene is mediated by conserved proximal promoter elements. J Immunol. 1993 Oct 15; 151(8):4173-82.
    View in: PubMed
  247. Baskar S, Nabavi N, Glimcher LH, Ostrand-Rosenberg S. Tumor cells expressing major histocompatibility complex class II and B7 activation molecules stimulate potent tumor-specific immunity. J Immunother Emphasis Tumor Immunol. 1993 Oct; 14(3):209-15.
    View in: PubMed
  248. Ponath PD, Fass D, Liou HC, Glimcher LH, Strominger JL. The regulatory gene, hXBP-1, and its target, HLA-DRA, utilize both common and distinct regulatory elements and protein complexes. J Biol Chem. 1993 Aug 15; 268(23):17074-82.
    View in: PubMed
  249. Laufer TM, von Herrath MG, Grusby MJ, Oldstone MB, Glimcher LH. Autoimmune diabetes can be induced in transgenic major histocompatibility complex class II-deficient mice. J Exp Med. 1993 Aug 1; 178(2):589-96.
    View in: PubMed
  250. Baskar S, Ostrand-Rosenberg S, Nabavi N, Nadler LM, Freeman GJ, Glimcher LH. Constitutive expression of B7 restores immunogenicity of tumor cells expressing truncated major histocompatibility complex class II molecules. Proc Natl Acad Sci U S A. 1993 Jun 15; 90(12):5687-90.
    View in: PubMed
  251. Todd MD, Grusby MJ, Lederer JA, Lacy E, Lichtman AH, Glimcher LH. Transcription of the interleukin 4 gene is regulated by multiple promoter elements. J Exp Med. 1993 Jun 1; 177(6):1663-74.
    View in: PubMed
  252. Jevnikar AM, Singer GG, Coffman T, Glimcher LH, Kelley VE. Transgenic tubular cell expression of class II is insufficient to initiate immune renal injury. J Am Soc Nephrol. 1993 Jun; 3(12):1972-7.
    View in: PubMed
  253. Clauss IM, Gravallese EM, Darling JM, Shapiro F, Glimcher MJ, Glimcher LH. In situ hybridization studies suggest a role for the basic region-leucine zipper protein hXBP-1 in exocrine gland and skeletal development during mouse embryogenesis. Dev Dyn. 1993 Jun; 197(2):146-56.
    View in: PubMed
  254. Kara CJ, Glimcher LH. Developmental and cytokine-mediated regulation of MHC class II gene promoter occupancy in vivo. J Immunol. 1993 Jun 1; 150(11):4934-42.
    View in: PubMed
  255. Grusby MJ, Auchincloss H, Lee R, Johnson RS, Spencer JP, Zijlstra M, Jaenisch R, Papaioannou VE, Glimcher LH. Mice lacking major histocompatibility complex class I and class II molecules. Proc Natl Acad Sci U S A. 1993 May 1; 90(9):3913-7.
    View in: PubMed
  256. Auchincloss H, Lee R, Shea S, Markowitz JS, Grusby MJ, Glimcher LH. The role of "indirect" recognition in initiating rejection of skin grafts from major histocompatibility complex class II-deficient mice. Proc Natl Acad Sci U S A. 1993 Apr 15; 90(8):3373-7.
    View in: PubMed
  257. Markowitz JS, Auchincloss H, Grusby MJ, Glimcher LH. Class II-positive hematopoietic cells cannot mediate positive selection of CD4+ T lymphocytes in class II-deficient mice. Proc Natl Acad Sci U S A. 1993 Apr 1; 90(7):2779-83.
    View in: PubMed
  258. Markowitz JS, Rogers PR, Grusby MJ, Parker DC, Glimcher LH. B lymphocyte development and activation independent of MHC class II expression. J Immunol. 1993 Feb 15; 150(4):1223-33.
    View in: PubMed
  259. Jevnikar AM, Singer GG, Coffman T, Glimcher LH, Kelley VE. Renal tubular cell expression of MHC class II (I-Eb) is insufficient to initiate immune injury in a transgenic kidney transplant model. Transplant Proc. 1993 Feb; 25(1 Pt 1):142-3.
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  260. Cantor H, Crump AL, Raman VK, Liu H, Markowitz JS, Grusby MJ, Glimcher LH. Immunoregulatory effects of superantigens: interactions of staphylococcal enterotoxins with host MHC and non-MHC products. Immunol Rev. 1993 Feb; 131:27-42.
    View in: PubMed
  261. Lee R, Glimcher LH, Auchincloss H. Evidence that a "four-cell cluster" may prime cytotoxic T-cells during graft rejection. Transplant Proc. 1993 Feb; 25(1 Pt 2):847-9.
    View in: PubMed
  262. Kara CJ, Glimcher LH. Three in vivo promoter phenotypes in MHC class II deficient combined immunodeficiency. Immunogenetics. 1993; 37(3):227-30.
    View in: PubMed
  263. Kara CJ, Glimcher LH. Promoter accessibility within the environment of the MHC is affected in class II-deficient combined immunodeficiency. EMBO J. 1993 Jan; 12(1):187-93.
    View in: PubMed
  264. Nabavi N, Freeman GJ, Gault A, Godfrey D, Nadler LM, Glimcher LH. Signalling through the MHC class II cytoplasmic domain is required for antigen presentation and induces B7 expression. Nature. 1992 Nov 19; 360(6401):266-8.
    View in: PubMed
  265. Hong SC, Chelouche A, Lin RH, Shaywitz D, Braunstein NS, Glimcher L, Janeway CA. An MHC interaction site maps to the amino-terminal half of the T cell receptor alpha chain variable domain. Cell. 1992 Jun 12; 69(6):999-1009.
    View in: PubMed
  266. Ivashkiv LB, Fleming MD, Glimcher LH. Dominant negative mutants of transcription factor mXBP (CRE-BP1, ATF-2). New Biol. 1992 Apr; 4(4):360-8.
    View in: PubMed
  267. Glimcher LH, Kara CJ. Sequences and factors: a guide to MHC class-II transcription. Annu Rev Immunol. 1992; 10:13-49.
    View in: PubMed
  268. Ivashkiv LB, Glimcher LH. Repression of class II major histocompatibility complex genes by cyclic AMP is mediated by conserved promoter elements. J Exp Med. 1991 Dec 1; 174(6):1583-92.
    View in: PubMed
  269. Rothman P, Li SC, Gorham B, Glimcher L, Alt F, Boothby M. Identification of a conserved lipopolysaccharide-plus-interleukin-4-responsive element located at the promoter of germ line epsilon transcripts. Mol Cell Biol. 1991 Nov; 11(11):5551-61.
    View in: PubMed
  270. Gravallese EM, Darling JM, Glimcher LH, Boothby M. Role of lipopolysaccharide and IL-4 in control of transcription of the class II A alpha gene. J Immunol. 1991 Oct 1; 147(7):2377-83.
    View in: PubMed
  271. Grusby MJ, Johnson RS, Papaioannou VE, Glimcher LH. Depletion of CD4+ T cells in major histocompatibility complex class II-deficient mice. Science. 1991 Sep 20; 253(5026):1417-20.
    View in: PubMed
  272. Whitley MZ, Sisk R, Ivashkiv LB, Finn PW, Glimcher LH, Boothby MR. Non-consensus DNA sequences function in a cell-type-specific enhancer of the mouse class II MHC gene A alpha. Int Immunol. 1991 Sep; 3(9):877-88.
    View in: PubMed
  273. Gravallese EM, Darling JM, Ladd AL, Katz JN, Glimcher LH. In situ hybridization studies of stromelysin and collagenase messenger RNA expression in rheumatoid synovium. Arthritis Rheum. 1991 Sep; 34(9):1076-84.
    View in: PubMed
  274. Jevnikar AM, Brennan DC, Singer GG, Heng JE, Maslinski W, Wuthrich RP, Glimcher LH, Kelley VE. Stimulated kidney tubular epithelial cells express membrane associated and secreted TNF alpha. Kidney Int. 1991 Aug; 40(2):203-11.
    View in: PubMed
  275. Finn PW, Kara CJ, Grusby MJ, Folsom V, Glimcher LH. Upstream elements of the MHC class II E beta gene active in B cells. J Immunol. 1991 Jun 1; 146(11):4011-5.
    View in: PubMed
  276. Ono SJ, Liou HC, Davidon R, Strominger JL, Glimcher LH. Human X-box-binding protein 1 is required for the transcription of a subset of human class II major histocompatibility genes and forms a heterodimer with c-fos. Proc Natl Acad Sci U S A. 1991 May 15; 88(10):4309-12.
    View in: PubMed
  277. Kara CJ, Glimcher LH. In vivo footprinting of MHC class II genes: bare promoters in the bare lymphocyte syndrome. Science. 1991 May 3; 252(5006):709-12.
    View in: PubMed
  278. Jevnikar AM, Wuthrich RP, Brennan DC, Maslinski W, Glimcher LH, Rubin-Kelley VE. TNF-alpha is expressed on the surface of kidney proximal tubular cells. Transplant Proc. 1991 Feb; 23(1 Pt 1):231-2.
    View in: PubMed
  279. Kara CJ, Glimcher LH. Regulation of MHC class II gene transcription. Curr Opin Immunol. 1991 Feb; 3(1):16-21.
    View in: PubMed
  280. Liou HC, Eddy R, Shows T, Lisowska-Grospierre B, Griscelli C, Doyle C, Mannhalter J, Eibl M, Glimcher LH. An HLA-DR alpha promoter DNA-binding protein is expressed ubiquitously and maps to human chromosomes 22 and 5. Immunogenetics. 1991; 34(5):286-92.
    View in: PubMed
  281. Li SC, Rothman P, Boothby M, Ferrier P, Glimcher L, Alt FW. Control of immunoglobulin heavy chain constant region gene expression. Adv Exp Med Biol. 1991; 292:245-51.
    View in: PubMed
  282. Fontaine B, Hanson MP, Liou HC, Glimcher LH, Rouleau GA, Gusella JF. BanI polymorphism at the XBP1 locus. Nucleic Acids Res. 1990 Sep 25; 18(18):5578.
    View in: PubMed
  283. Jevnikar AM, Wuthrich RP, Takei F, Xu HW, Brennan DC, Glimcher LH, Rubin-Kelley VE. Differing regulation and function of ICAM-1 and class II antigens on renal tubular cells. Kidney Int. 1990 Sep; 38(3):417-25.
    View in: PubMed
  284. Grusby MJ, Mitchell SC, Nabavi N, Glimcher LH. Casein expression in cytotoxic T lymphocytes. Proc Natl Acad Sci U S A. 1990 Sep; 87(17):6897-901.
    View in: PubMed
  285. Scholl PR, Sekaly RP, Diez A, Glimcher LH, Geha RS. Binding of toxic shock syndrome toxin-1 to murine major histocompatibility complex class II molecules. Eur J Immunol. 1990 Sep; 20(9):1911-6.
    View in: PubMed
  286. Grusby MJ, Mitchell SC, Glimcher LH. Molecular cloning of mouse cathepsin D. Nucleic Acids Res. 1990 Jul 11; 18(13):4008.
    View in: PubMed
  287. Brown MA, Griffith IJ, Glimcher LH. Functional and molecular characterization of I-A kappa beta mutants is consistent with the predicted three dimensional structure of class II MHC molecules. Mol Immunol. 1990 Jul; 27(7):645-50.
    View in: PubMed
  288. Finn PW, Van TT, Accolla RS, Glimcher LH. Loss of a DNA-protein complex correlates with extinguished major histocompatibility complex class II expression in a human B cell. J Exp Med. 1990 Jun 1; 171(6):2159-64.
    View in: PubMed
  289. Finn PW, Kara CJ, Van TT, Douhan J, Boothby MR, Glimcher LH. The presence of a DNA binding complex correlates with E beta class II MHC gene expression. EMBO J. 1990 May; 9(5):1543-9.
    View in: PubMed
  290. Kara CJ, Liou HC, Ivashkiv LB, Glimcher LH. A cDNA for a human cyclic AMP response element-binding protein which is distinct from CREB and expressed preferentially in brain. Mol Cell Biol. 1990 Apr; 10(4):1347-57.
    View in: PubMed
  291. Ivashkiv LB, Liou HC, Kara CJ, Lamph WW, Verma IM, Glimcher LH. mXBP/CRE-BP2 and c-Jun form a complex which binds to the cyclic AMP, but not to the 12-O-tetradecanoylphorbol-13-acetate, response element. Mol Cell Biol. 1990 Apr; 10(4):1609-21.
    View in: PubMed
  292. Liou HC, Boothby MR, Finn PW, Davidon R, Nabavi N, Zeleznik-Le NJ, Ting JP, Glimcher LH. A new member of the leucine zipper class of proteins that binds to the HLA DR alpha promoter. Science. 1990 Mar 30; 247(4950):1581-4.
    View in: PubMed
  293. Grusby MJ, Nabavi N, Wong H, Dick RF, Bluestone JA, Schotz MC, Glimcher LH. Cloning of an interleukin-4 inducible gene from cytotoxic T lymphocytes and its identification as a lipase. Cell. 1990 Feb 9; 60(3):451-9.
    View in: PubMed
  294. Wuthrich RP, Glimcher LH, Yui MA, Jevnikar AM, Dumas SE, Kelley VE. MHC class II, antigen presentation and tumor necrosis factor in renal tubular epithelial cells. Kidney Int. 1990 Feb; 37(2):783-92.
    View in: PubMed
  295. Wuthrich RP, Jevnikar AM, Takei F, Glimcher LH, Kelley VE. Intercellular adhesion molecule-1 (ICAM-1) expression is upregulated in autoimmune murine lupus nephritis. Am J Pathol. 1990 Feb; 136(2):441-50.
    View in: PubMed
  296. Finn PW, Kara CJ, Douhan J, Van TT, Folsom V, Glimcher LH. Interferon gamma regulates binding of two nuclear protein complexes in a macrophage cell line. Proc Natl Acad Sci U S A. 1990 Feb; 87(3):914-8.
    View in: PubMed
  297. Nabavi N, Grusby MJ, Finn PW, Wolgemuth DJ, Glimcher LH. Identification of an IL-4-inducible gene expressed in differentiating lymphocytes and male germ cells. Dev Immunol. 1990; 1(1):19-30.
    View in: PubMed
  298. Boothby M, Liou HC, Finn PW, Gravallese E, Glimcher LH. Control of transcription at the murine A alpha locus. Immunol Res. 1990; 9(2):77-92.
    View in: PubMed
  299. Ghogawala Z, Choi E, Daly KR, Blanco LR, Griffith IJ, Glimcher LH. An intronic 10-base-pair deletion in a class II A beta gene affects RNA processing. Mol Cell Biol. 1989 Oct; 9(10):4402-8.
    View in: PubMed
  300. Gravallese EM, Boothby MR, Smas CM, Glimcher LH. A lipopolysaccharide-induced DNA-binding protein for a class II gene in B cells is distinct from NF-kappa B. Mol Cell Biol. 1989 Aug; 9(8):3184-92.
    View in: PubMed
  301. St-Pierre Y, Nabavi N, Ghogawala Z, Glimcher LH, Watts TH. A functional role for signal transduction via the cytoplasmic domains of MHC class II proteins. J Immunol. 1989 Aug 1; 143(3):808-12.
    View in: PubMed
  302. Johnson NA, Carland F, Allen PM, Glimcher LH. T cell receptor gene segment usage in a panel of hen-egg white lysozyme specific, I-Ak-restricted T helper hybridomas. J Immunol. 1989 May 1; 142(9):3298-304.
    View in: PubMed
  303. Nabavi N, Ghogawala Z, Myer A, Griffith IJ, Wade WF, Chen ZZ, McKean DJ, Glimcher LH. Antigen presentation abrogated in cells expressing truncated Ia molecules. J Immunol. 1989 Mar 1; 142(5):1444-7.
    View in: PubMed
  304. Boothby M, Liou HC, Glimcher LH. Differences in DNA sequence specificity among MHC class II X box binding proteins. J Immunol. 1989 Feb 1; 142(3):1005-14.
    View in: PubMed
  305. Wuthrich RP, Yui MA, Mazoujian G, Nabavi N, Glimcher LH, Kelley VE. Enhanced MHC class II expression in renal proximal tubules precedes loss of renal function in MRL/lpr mice with lupus nephritis. Am J Pathol. 1989 Jan; 134(1):45-51.
    View in: PubMed
  306. Boothby M, Gravallese E, Liou HC, Glimcher LH. A DNA binding protein regulated by IL-4 and by differentiation in B cells. Science. 1988 Dec 16; 242(4885):1559-62.
    View in: PubMed
  307. Liou HC, Boothby MR, Glimcher LH. Distinct cloned class II MHC DNA binding proteins recognize the X box transcription element. Science. 1988 Oct 7; 242(4875):69-71.
    View in: PubMed
  308. Griffith IJ, Ghogawala Z, Nabavi N, Golan DE, Myer A, McKean DJ, Glimcher LH. Cytoplasmic domain affects membrane expression and function of an Ia molecule. Proc Natl Acad Sci U S A. 1988 Jul; 85(13):4847-51.
    View in: PubMed
  309. McMillan VM, Dennis GJ, Glimcher LH, Finkelman FD, Mond JJ. Corticosteroid induction of Ig+Ia- B cells in vitro is mediated via interaction with the glucocorticoid cytoplasmic receptor. J Immunol. 1988 Apr 15; 140(8):2549-55.
    View in: PubMed
  310. Liou HC, Polla BS, Aragnol D, Leserman LD, Griffith IJ, Glimcher LH. A tissue-specific DNase I-hypersensitive site in a class II A alpha gene is under trans-regulatory control. Proc Natl Acad Sci U S A. 1988 Apr; 85(8):2738-42.
    View in: PubMed
  311. Griffith IJ, Nabavi N, Ghogawala Z, Chase CG, Rodriguez M, McKean DJ, Glimcher LH. Structural mutation affecting intracellular transport and cell surface expression of murine class II molecules. J Exp Med. 1988 Feb 1; 167(2):541-55.
    View in: PubMed
  312. Polla BS, Ohara J, Paul WE, Nabavi N, Myer A, Liou HC, Shen FW, Gillis S, Bonventre JV, Glimcher LH, et al. Differential induction of class II gene expression in murine pre-B-cell lines by B-cell stimulatory factor-1 and by antibodies to B-cell surface antigens. J Mol Cell Immunol. 1988; 3(6):363-73.
    View in: PubMed
  313. Griffith IJ, Carland FM, Glimcher LH. Alteration of a non-polymorphic residue in a class II E beta gene eliminates an antibody-defined epitope without affecting T cell recognition. J Immunol. 1987 Jun 15; 138(12):4480-3.
    View in: PubMed
  314. Glimcher LH, Polla BS, Poljak A, Morton CC, McKean DJ. Murine class II (Ia) molecules associate with human invariant chain. J Immunol. 1987 Mar 1; 138(5):1519-23.
    View in: PubMed
  315. Griffith IJ, Choi EM, Glimcher LH. A single base mutation in an I-A alpha-chain gene alters T-cell recognition. Proc Natl Acad Sci U S A. 1987 Feb; 84(4):1090-3.
    View in: PubMed
  316. Takaháma Y, Ono S, Glimcher LH, Hamaoka T. Polyclonal B-cell activation by a B-cell differentiation factor B151-TRF2. IV. B151-TRF2-responsive F1 B cells consist of two separate populations capable of recognizing only one of the parental I-A products expressed on B cells. J Mol Cell Immunol. 1987; 3(3):177-94.
    View in: PubMed
  317. Polla BS, Poljak A, Geier S, Nathenson SG, Ohara J, Paul WE, Glimcher LH. Regulation of class II gene expression in a murine pre-B cell line. Fed Proc. 1986 Dec; 45(13):2995-9.
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  318. Polla BS, Poljak A, Ohara J, Paul WE, Glimcher LH. Regulation of class II gene expression: analysis in B cell stimulatory factor 1-inducible murine pre-B cell lines. J Immunol. 1986 Nov 15; 137(10):3332-7.
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  319. Polla BS, Poljak A, Geier SG, Nathenson SG, Ohara J, Paul WE, Glimcher LH. Three distinct signals can induce class II gene expression in a murine pre-B-cell line. Proc Natl Acad Sci U S A. 1986 Jul; 83(13):4878-82.
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  320. Quill H, Schwartz RH, Glimcher LH. Ek beta mutant antigen-presenting cell lines expressing altered Ak alpha molecules. J Immunol. 1986 May 1; 136(9):3351-9.
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  321. Germain RN, Braunstein NS, Brown MA, Glimcher LH, Lechler RI, McCluskey J, Margulies DH, Miller J, Norcross MA, Paul WE, et al. Structure and function of murine class II major histocompatibility complex genes. Mt Sinai J Med. 1986 Mar; 53(3):194-201.
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  322. Hattori M, Buse JB, Jackson RA, Glimcher L, Dorf ME, Minami M, Makino S, Moriwaki K, Kuzuya H, Imura H, et al. The NOD mouse: recessive diabetogenic gene in the major histocompatibility complex. Science. 1986 Feb 14; 231(4739):733-5.
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  323. Cohn LE, Glimcher LH, Waldmann RA, Smith JA, Ben-Nun A, Seidman JG, Choi E. Identification of functional regions on the I-Ab molecule by site-directed mutagenesis. Proc Natl Acad Sci U S A. 1986 Feb; 83(3):747-51.
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  324. Chatterjee-Das S, Schlauder GG, Sachs DH, Glimcher LH, Paul WE, McKean DJ. A biochemical analysis of Ak molecules from mutant antigen presenting cell lines. Immunogenetics. 1986; 23(2):121-5.
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  325. Glimcher LH, McKean DJ, Choi E, Seidman JG. Complex regulation of class II gene expression: analysis with class II mutant cell lines. J Immunol. 1985 Nov; 135(5):3542-50.
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  326. Allen PM, McKean DJ, Beck BN, Sheffield J, Glimcher LH. Direct evidence that a class II molecule and a simple globular protein generate multiple determinants. J Exp Med. 1985 Oct 1; 162(4):1264-74.
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  327. Malek TR, Chan C, Glimcher LH, Germain RN, Shevach EM. Influence of accessory cell and T cell surface antigens on mitogen-induced IL 2 receptor expression. J Immunol. 1985 Sep; 135(3):1826-33.
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  328. Heilig JS, Glimcher LH, Kranz DM, Clayton LK, Greenstein JL, Saito H, Maxam AM, Burakoff SJ, Eisen HN, Tonegawa S. Expression of the T-cell-specific gamma gene is unnecessary in T cells recognizing class II MHC determinants. Nature. 1985 Sep 5-11; 317(6032):68-70.
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  329. Ben-Nun A, Choi E, McIntyre KR, Leeman SA, McKean DJ, Seidman JG, Glimcher LH. DNA-mediated transfer of major histocompatibility class II I-Ab and I-Abm12 genes into B lymphoma cells: molecular and functional analysis of introduced antigens. J Immunol. 1985 Aug; 135(2):1456-64.
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  330. Mizuochi T, Golding H, Rosenberg AS, Glimcher LH, Malek TR, Singer A. Both L3T4+ and Lyt-2+ helper T cells initiate cytotoxic T lymphocyte responses against allogenic major histocompatibility antigens but not against trinitrophenyl-modified self. J Exp Med. 1985 Aug 1; 162(2):427-43.
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  331. Glimcher LH, Schwartz RH. Analysis of responder cell-cell interactions in the syngeneic mixed leukocyte response. Cell Immunol. 1985 Jun; 93(1):157-67.
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  332. Schlauder GG, Bell MP, Paul WE, Glimcher LH, McKean DJ. Biochemical characterization of I-Ak proteins from mutant antigen-presenting B-cell--B-lymphoma hybridomas. Mol Immunol. 1985 May; 22(5):597-607.
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  333. Makoul GT, Robinson DR, Bhalla AK, Glimcher LH. Prostaglandin E2 inhibits the activation of cloned T cell hybridomas. J Immunol. 1985 Apr; 134(4):2645-50.
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  334. Glimcher LH, Serog B, McKean DJ, Beck BN. Evidence that autoreactive T hybridomas recognize multiple epitopes on the I-Ak molecule. J Immunol. 1985 Mar; 134(3):1780-6.
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  335. Ben-Nun A, Strauss W, Leeman SA, Cohn LE, Murre C, Duby A, Seidman JG, Glimcher LH. An Ia-positive mouse T-cell clone is functional in presenting antigen to other T cells. Immunogenetics. 1985; 22(2):123-30.
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  336. Beck BN, Glimcher LH, Nilson AE, Pierres M, McKean DJ. The structure-function relationship of I-A molecules: correlation of serologic and functional phenotypes of four I-Ak mutant cell lines. J Immunol. 1984 Dec; 133(6):3176-82.
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  337. Bhalla AK, Amento EP, Serog B, Glimcher LH. 1,25-Dihydroxyvitamin D3 inhibits antigen-induced T cell activation. J Immunol. 1984 Oct; 133(4):1748-54.
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  338. Cronin PS, Sing AP, Glimcher LH, Kelley VE, Reinisch CL. The isolation and functional characterization of autoimmune clones expressing inappropriate Ia. J Immunol. 1984 Aug; 133(2):822-9.
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  339. Ben-Nun A, Glimcher LH, Weis J, Seidman JG. Functional expression of a cloned I-A beta k gene in B-lymphoma cells. Science. 1984 Feb 24; 223(4638):825-8.
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  340. Glimcher LH, Schroer JA, Chan C, Shevach EM. Fine specificity of cloned insulin-specific T cell hybridomas: evidence supporting a role for tertiary conformation. J Immunol. 1983 Dec; 131(6):2868-74.
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  341. Glimcher LH, Sharrow SO, Paul WE. Serologic and functional characterization of a panel of antigen-presenting cell lines expressing mutant I-A class II molecules. J Exp Med. 1983 Nov 1; 158(5):1573-88.
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  342. Matis LA, Glimcher LH, Paul WE, Schwartz RH. Magnitude of response of histocompatibility-restricted T-cell clones is a function of the product of the concentrations of antigen and Ia molecules. Proc Natl Acad Sci U S A. 1983 Oct; 80(19):6019-23.
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  343. Dos Reis GA, Glimcher LH, Shevach EM. T cell clones and hybridomas as probes for the analysis of the syngeneic mixed leukocyte reaction. Behring Inst Mitt. 1983 May; (72):59-66.
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  344. Glimcher LH, Hamano T, Asofsky R, Sachs DH, Pierres M, Samelson LE, Sharrow SO, Paul WE. IA mutant functional antigen-presenting cell lines. J Immunol. 1983 May; 130(5):2287-94.
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  345. Glimcher LH, Kruisbeek AM, Paul WE, Green I. Functional activity of a transformed thymic epithelial cell line. Scand J Immunol. 1983 Jan; 17(1):1-11.
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  346. Glimcher LH, Schwartz RH, Longo DL, Singer A. The specificity of the syngeneic mixed leukocyte response, a primary anti-I region T cell proliferative response, is determined intrathymically. J Immunol. 1982 Sep; 129(3):987-91.
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  347. Glimcher LH, Shevach EM. Production of autoreactive I region-restricted T cell hybridomas. J Exp Med. 1982 Aug 1; 156(2):640-5.
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  348. Glimcher LH, Hamano T, Asofsky R, Herber-Katz E, Hedrick S, Schwartz RH, Paul WE. I region-restricted antigen presentation by B cell-B lymphoma hybridomas. Nature. 1982 Jul 15; 298(5871):283-4.
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  349. Glimcher LH, Cantor H. T-cell sets that control B-cell secretion of antigen-specific immunoglobulin also control secretion of nonspecific immunoglobulin. Cell Immunol. 1982 Jul 1; 70(2):271-6.
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  350. Glimcher LH, Kim KJ, Green I, Paul WE. Ia antigen-bearing B cell tumor lines can present protein antigen and alloantigen in a major histocompatibility complex-restricted fashion to antigen-reactive T cells. J Exp Med. 1982 Feb 1; 155(2):445-59.
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  351. Glimcher LH, Longo DL, Green I, Schwartz RH. Murine syngeneic mixed lymphocyte response. I. Target antigens are self Ia molecules. J Exp Med. 1981 Nov 1; 154(5):1652-70.
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  352. Taurog JD, Raveche ES, Smathers PA, Glimcher LH, Huston DP, Hansen CT, Steinberg AD. T cell abnormalities in NZB mice occur independently of autoantibody production. J Exp Med. 1981 Feb 1; 153(2):221-34.
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  353. Glimcher LH, Steinberg AD, House SB, Green I. The autologous mixed lymphocyte reaction in strains of mice with autoimmune disease. J Immunol. 1980 Oct; 125(4):1832-8.
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  354. Cantor H, Kasai M, Shen FW, Leclerc JC, Glimcher L. Immunogenetic analysis of "natural killer" activity in the mouse. Immunol Rev. 1979; 44:3-12.
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  355. Burakoff SJ, Finberg R, Glimcher L, Lemonnier F, Benacerraf B, Cantor H. The biologic significance of alloreactivity. The ontogeny of T-cell sets specific for alloantigens or modified self antigens. J Exp Med. 1978 Nov 1; 148(5):1414-22.
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  356. Glimcher L, Shen FW, Cantor H. Identification of a cell-surface antigen selectively expressed on the natural killer cell. J Exp Med. 1977 Jan 1; 145(1):1-9.
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