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Michael Lewis Steer, M.D.

TitleProfessor of Surgery, Emeritus
InstitutionBeth Israel Deaconess Medical Center
DepartmentEmeritus
AddressBeth Israel Deaconess Med Ctr
Surgery
330 Brookline Ave
Boston MA 02215
Phone617/667-4261
Fax617/667-2978

 Bibliographic 
 selected publications
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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  1. Michael ES, Kuliopulos A, Covic L, Steer ML, Perides G. Pharmacological inhibition of PAR2 with the pepducin P2pal-18S protects mice against acute experimental biliary pancreatitis. Am J Physiol Gastrointest Liver Physiol. 2013 Mar; 304(5):G516-26.
    View in: PubMed
  2. Sullivan SR, Hughes CD, Raymonville M, Rogers SO, Steer ML, Meara JG. Training global surgery fellows. Bull Am Coll Surg. 2012 Aug; 97(8):46-50.
    View in: PubMed
  3. Perides G, Weiss ER, Michael ES, Laukkarinen JM, Duffield JS, Steer ML. TNF-alpha-dependent regulation of acute pancreatitis severity by Ly-6C(hi) monocytes in mice. J Biol Chem. 2011 Apr 15; 286(15):13327-35.
    View in: PubMed
  4. Perides G, van Acker GJ, Laukkarinen JM, Steer ML. Experimental acute biliary pancreatitis induced by retrograde infusion of bile acids into the mouse pancreatic duct. Nat Protoc. 2010 Feb; 5(2):335-41.
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  5. Sullivan SR, Taylor HO, Pauyo T, Steer ML. Surgeons' dispatch from Cange, Haiti. N Engl J Med. 2010 Feb 18; 362(7):e19.
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  6. Perides G, Laukkarinen JM, Vassileva G, Steer ML. Biliary acute pancreatitis in mice is mediated by the G-protein-coupled cell surface bile acid receptor Gpbar1. Gastroenterology. 2010 Feb; 138(2):715-25.
    View in: PubMed
  7. Laukkarinen JM, Weiss ER, van Acker GJ, Steer ML, Perides G. Protease-activated receptor-2 exerts contrasting model-specific effects on acute experimental pancreatitis. J Biol Chem. 2008 Jul 25; 283(30):20703-12.
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  8. Frossard JL, Steer ML, Pastor CM. Acute pancreatitis. Lancet. 2008 Jan 12; 371(9607):143-52.
    View in: PubMed
  9. Laukkarinen JM, Van Acker GJ, Weiss ER, Steer ML, Perides G. A mouse model of acute biliary pancreatitis induced by retrograde pancreatic duct infusion of Na-taurocholate. Gut. 2007 Nov; 56(11):1590-8.
    View in: PubMed
  10. Van Acker GJ, Perides G, Weiss ER, Das S, Tsichlis PN, Steer ML. Tumor progression locus-2 is a critical regulator of pancreatic and lung inflammation during acute pancreatitis. J Biol Chem. 2007 Jul 27; 282(30):22140-9.
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  11. Van Acker GJ, Weiss E, Steer ML, Perides G. Cause-effect relationships between zymogen activation and other early events in secretagogue-induced acute pancreatitis. Am J Physiol Gastrointest Liver Physiol. 2007 Jun; 292(6):G1738-46.
    View in: PubMed
  12. Ligon B, Yang J, Morin SB, Ruberti MF, Steer ML. Regulation of pancreatic islet cell survival and replication by gamma-aminobutyric acid. Diabetologia. 2007 Apr; 50(4):764-73.
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  13. Steer ML. 'The success of the mentee is the mentor's ultimate reward'. An interview with Dr. Michael L. Steer by Martin E. Fernandez-Zapico. Pancreatology. 2006; 6(6):507-9.
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  14. van Acker GJ, Perides G, Steer ML. Co-localization hypothesis: a mechanism for the intrapancreatic activation of digestive enzymes during the early phases of acute pancreatitis. World J Gastroenterol. 2006 Apr 7; 12(13):1985-90.
    View in: PubMed
  15. Sharma A, Tao X, Gopal A, Ligon B, Steer ML, Perides G. Calcium dependence of proteinase-activated receptor 2 and cholecystokinin-mediated amylase secretion from pancreatic acini. Am J Physiol Gastrointest Liver Physiol. 2005 Oct; 289(4):G686-95.
    View in: PubMed
  16. Perides G, Sharma A, Gopal A, Tao X, Dwyer K, Ligon B, Steer ML. Secretin differentially sensitizes rat pancreatic acini to the effects of supramaximal stimulation with caerulein. Am J Physiol Gastrointest Liver Physiol. 2005 Oct; 289(4):G713-21.
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  17. Perides G, Tao X, West N, Sharma A, Steer ML. A mouse model of ethanol dependent pancreatic fibrosis. Gut. 2005 Oct; 54(10):1461-7.
    View in: PubMed
  18. Sharma A, Tao X, Gopal A, Ligon B, Andrade-Gordon P, Steer ML, Perides G. Protection against acute pancreatitis by activation of protease-activated receptor-2. Am J Physiol Gastrointest Liver Physiol. 2005 Feb; 288(2):G388-95.
    View in: PubMed
  19. Severgnini M, Takahashi S, Rozo LM, Homer RJ, Kuhn C, Jhung JW, Perides G, Steer M, Hassoun PM, Fanburg BL, Cochran BH, Simon AR. Activation of the STAT pathway in acute lung injury. Am J Physiol Lung Cell Mol Physiol. 2004 Jun; 286(6):L1282-92.
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  20. Song AM, Bhagat L, Singh VP, Van Acker GG, Steer ML, Saluja AK. Inhibition of cyclooxygenase-2 ameliorates the severity of pancreatitis and associated lung injury. Am J Physiol Gastrointest Liver Physiol. 2002 Nov; 283(5):G1166-74.
    View in: PubMed
  21. Van Acker GJ, Saluja AK, Bhagat L, Singh VP, Song AM, Steer ML. Cathepsin B inhibition prevents trypsinogen activation and reduces pancreatitis severity. Am J Physiol Gastrointest Liver Physiol. 2002 Sep; 283(3):G794-800.
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  22. Frossard JL, Saluja AK, Mach N, Lee HS, Bhagat L, Hadenque A, Rubbia-Brandt L, Dranoff G, Steer ML. In vivo evidence for the role of GM-CSF as a mediator in acute pancreatitis-associated lung injury. Am J Physiol Lung Cell Mol Physiol. 2002 Sep; 283(3):L541-8.
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  23. Steer M. Pancreatitis severity: who calls the shots? Gastroenterology. 2002 Apr; 122(4):1168-72.
    View in: PubMed
  24. Frossard JL, Bhagat L, Lee HS, Hietaranta AJ, Singh VP, Song AM, Steer ML, Saluja AK. Both thermal and non-thermal stress protect against caerulein induced pancreatitis and prevent trypsinogen activation in the pancreas. Gut. 2002 Jan; 50(1):78-83.
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  25. Bhagat L, Singh VP, Song AM, van Acker GJ, Agrawal S, Steer ML, Saluja AK. Thermal stress-induced HSP70 mediates protection against intrapancreatic trypsinogen activation and acute pancreatitis in rats. Gastroenterology. 2002 Jan; 122(1):156-65.
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  26. Singh VP, Saluja AK, Bhagat L, van Acker GJ, Song AM, Soltoff SP, Cantley LC, Steer ML. Phosphatidylinositol 3-kinase-dependent activation of trypsinogen modulates the severity of acute pancreatitis. J Clin Invest. 2001 Nov; 108(9):1387-95.
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  27. Steer ML. Relationship between pancreatitis and lung diseases. Respir Physiol. 2001 Oct; 128(1):13-6.
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  28. Singh VP, Saluja AK, Bhagat L, Hietaranta AJ, Song A, Mykoniatis A, Van Acker GJ, Steer ML. Serine protease inhibitor causes F-actin redistribution and inhibition of calcium-mediated secretion in pancreatic acini. Gastroenterology. 2001 Jun; 120(7):1818-27.
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  29. Morrin MM, Kruskal JB, Raptopoulos V, Weisinger K, Farrell RJ, Steer ML, Kane RA. State-of-the-art ultrasonography is as accurate as helical computed tomography and computed tomographic angiography for detecting unresectable periampullary cancer. J Ultrasound Med. 2001 May; 20(5):481-90.
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  30. Bhatia M, Saluja AK, Singh VP, Frossard JL, Lee HS, Bhagat L, Gerard C, Steer ML. Complement factor C5a exerts an anti-inflammatory effect in acute pancreatitis and associated lung injury. Am J Physiol Gastrointest Liver Physiol. 2001 May; 280(5):G974-8.
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  31. Hietaranta AJ, Singh VP, Bhagat L, van Acker GJ, Song AM, Mykoniatis A, Steer ML, Saluja AK. Water immersion stress prevents caerulein-induced pancreatic acinar cell nf-kappa b activation by attenuating caerulein-induced intracellular Ca2+ changes. J Biol Chem. 2001 Jun 1; 276(22):18742-7.
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  32. Hietaranta AJ, Saluja AK, Bhagat L, Singh VP, Song AM, Steer ML. Relationship between NF-kappaB and trypsinogen activation in rat pancreas after supramaximal caerulein stimulation. Biochem Biophys Res Commun. 2001 Jan 12; 280(1):388-95.
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  33. Bishop MD, Steer M. Pancreatic cystic lymphangioma in an adult. Pancreas. 2001 Jan; 22(1):101-2.
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  34. Gao Y, Lecker S, Post MJ, Hietaranta AJ, Li J, Volk R, Li M, Sato K, Saluja AK, Steer ML, Goldberg AL, Simons M. Inhibition of ubiquitin-proteasome pathway-mediated I kappa B alpha degradation by a naturally occurring antibacterial peptide. J Clin Invest. 2000 Aug; 106(3):439-48.
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  35. Lee HS, Bhagat L, Frossard JL, Hietaranta A, Singh VP, Steer ML, Saluja AK. Water immersion stress induces heat shock protein 60 expression and protects against pancreatitis in rats. Gastroenterology. 2000 Jul; 119(1):220-9.
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  36. Bhagat L, Singh VP, Hietaranta AJ, Agrawal S, Steer ML, Saluja AK. Heat shock protein 70 prevents secretagogue-induced cell injury in the pancreas by preventing intracellular trypsinogen activation. J Clin Invest. 2000 Jul; 106(1):81-9.
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  37. Saldinger PF, Reilly M, Reynolds K, Raptopoulos V, Chuttani R, Steer ML, Matthews JB. Is CT angiography sufficient for prediction of resectability of periampullary neoplasms? J Gastrointest Surg. 2000 May-Jun; 4(3):233-7; discussion 238-9.
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  38. Steer ML. Cyclosporin and chronic pancreatitis: a supermodel? Gut. 1999 Aug; 45(2):167-8.
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  39. Kaiser AM, Saluja AK, Steer ML. Repetitive short-term obstructions of the common bile-pancreatic duct induce severe acute pancreatitis in the opossum. Dig Dis Sci. 1999 Aug; 44(8):1653-61.
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  40. Steer ML. Early events in acute pancreatitis. Baillieres Best Pract Res Clin Gastroenterol. 1999 Jul; 13(2):213-25.
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  41. Saluja AK, Bhagat L, Lee HS, Bhatia M, Frossard JL, Steer ML. Secretagogue-induced digestive enzyme activation and cell injury in rat pancreatic acini. Am J Physiol. 1999 Apr; 276(4 Pt 1):G835-42.
    View in: PubMed
  42. Frossard JL, Saluja A, Bhagat L, Lee HS, Bhatia M, Hofbauer B, Steer ML. The role of intercellular adhesion molecule 1 and neutrophils in acute pancreatitis and pancreatitis-associated lung injury. Gastroenterology. 1999 Mar; 116(3):694-701.
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  43. Hofbauer B, Saluja AK, Bhatia M, Frossard JL, Lee HS, Bhagat L, Steer ML. Effect of recombinant platelet-activating factor acetylhydrolase on two models of experimental acute pancreatitis. Gastroenterology. 1998 Nov; 115(5):1238-47.
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  44. Bhatia M, Saluja AK, Hofbauer B, Lee HS, Frossard JL, Steer ML. The effects of neutrophil depletion on a completely noninvasive model of acute pancreatitis-associated lung injury. Int J Pancreatol. 1998 Oct; 24(2):77-83.
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  45. Hofbauer B, Saluja AK, Lerch MM, Bhagat L, Bhatia M, Lee HS, Frossard JL, Adler G, Steer ML. Intra-acinar cell activation of trypsinogen during caerulein-induced pancreatitis in rats. Am J Physiol. 1998 Aug; 275(2 Pt 1):G352-62.
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  46. Steer ML. Frank Brooks memorial Lecture: The early intraacinar cell events which occur during acute pancreatitis. Pancreas. 1998 Jul; 17(1):31-7.
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  47. Bhatia M, Wallig MA, Hofbauer B, Lee HS, Frossard JL, Steer ML, Saluja AK. Induction of apoptosis in pancreatic acinar cells reduces the severity of acute pancreatitis. Biochem Biophys Res Commun. 1998 May 19; 246(2):476-83.
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  48. Bhatia M, Saluja AK, Hofbauer B, Frossard JL, Lee HS, Castagliuolo I, Wang CC, Gerard N, Pothoulakis C, Steer ML. Role of substance P and the neurokinin 1 receptor in acute pancreatitis and pancreatitis-associated lung injury. Proc Natl Acad Sci U S A. 1998 Apr 14; 95(8):4760-5.
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  49. Gerard C, Frossard JL, Bhatia M, Saluja A, Gerard NP, Lu B, Steer M. Targeted disruption of the beta-chemokine receptor CCR1 protects against pancreatitis-associated lung injury. J Clin Invest. 1997 Oct 15; 100(8):2022-7.
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  50. McKee JD, Raju GP, Edelman RR, Levine H, Steer M, Chuttani R. MR cholangiopancreatography (MRCP) in diagnosis of afferent loop syndrome presenting as cholangitis. Dig Dis Sci. 1997 Oct; 42(10):2082-6.
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  51. Roy-Chaudhury P, Meisels IS, Freedman S, Steinman TI, Steer M. Combined gastric and ileocecal toxicity (serpiginous ulcers) after oral kayexalate in sorbital therapy. Am J Kidney Dis. 1997 Jul; 30(1):120-2.
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  52. Saluja AK, Donovan EA, Yamanaka K, Yamaguchi Y, Hofbauer B, Steer ML. Cerulein-induced in vitro activation of trypsinogen in rat pancreatic acini is mediated by cathepsin B. Gastroenterology. 1997 Jul; 113(1):304-10.
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  53. Raptopoulos V, Steer ML, Sheiman RG, Vrachliotis TG, Gougoutas CA, Movson JS. The use of helical CT and CT angiography to predict vascular involvement from pancreatic cancer: correlation with findings at surgery. AJR Am J Roentgenol. 1997 Apr; 168(4):971-7.
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  54. Saluja AK, Lu L, Yamaguchi Y, Hofbauer B, Rünzi M, Dawra R, Bhatia M, Steer ML. A cholecystokinin-releasing factor mediates ethanol-induced stimulation of rat pancreatic secretion. J Clin Invest. 1997 Feb 1; 99(3):506-12.
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  55. Siewert B, Raptopoulos V, Mueller MF, Rosen MP, Steer M. Impact of CT on diagnosis and management of acute abdomen in patients initially treated without surgery. AJR Am J Roentgenol. 1997 Jan; 168(1):173-8.
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  56. Steer ML. Pathogenesis of acute pancreatitis. Digestion. 1997; 58 Suppl 1:46-9.
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  57. Yamanaka K, Saluja AK, Brown GE, Yamaguchi Y, Hofbauer B, Steer ML. Protective effects of prostaglandin E1 on acute lung injury of caerulein-induced acute pancreatitis in rats. Am J Physiol. 1997 Jan; 272(1 Pt 1):G23-30.
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  58. Waxman I, Steer ML, Freedman SD. Endoscopically assisted direct pancreatic function testing: a simplified technique. Gastrointest Endosc. 1996 Nov; 44(5):630.
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  59. Kaiser AM, Saluja AK, Lu L, Yamanaka K, Yamaguchi Y, Steer ML. Effects of cycloheximide on pancreatic endonuclease activity, apoptosis, and severity of acute pancreatitis. Am J Physiol. 1996 Sep; 271(3 Pt 1):C982-93.
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  60. Grady T, Saluja A, Kaiser A, Steer M. Edema and intrapancreatic trypsinogen activation precede glutathione depletion during caerulein pancreatitis. Am J Physiol. 1996 Jul; 271(1 Pt 1):G20-6.
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  61. Saluja A, Hofbauer B, Yamaguchi Y, Yamanaka K, Steer M. Induction of apoptosis reduces the severity of caerulein-induced pancreatitis in mice. Biochem Biophys Res Commun. 1996 Mar 27; 220(3):875-8.
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  62. Steer ML, Saluja AK. Lysosomal enzymes and pancreatitis. Gastroenterology. 1996 Mar; 110(3):965-7.
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  63. Kaiser AM, Saluja AK, Sengupta A, Saluja M, Steer ML. Relationship between severity, necrosis, and apoptosis in five models of experimental acute pancreatitis. Am J Physiol. 1995 Nov; 269(5 Pt 1):C1295-304.
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  64. Rünzi M, Saluja A, Kaiser A, Gerdes D, Sengupta A, Steer ML. Biochemical and morphological changes that characterise recovery from necrotising biliary pancreatitis in the opossum. Gut. 1995 Sep; 37(3):427-33.
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  65. Kaiser AM, Grady T, Gerdes D, Saluja M, Steer ML. Intravenous contrast medium does not increase the severity of acute necrotizing pancreatitis in the opossum. Dig Dis Sci. 1995 Jul; 40(7):1547-53.
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  66. Steer ML, Waxman I, Freedman S. Chronic pancreatitis. N Engl J Med. 1995 Jun 1; 332(22):1482-90.
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  67. Rünzi M, Raptopoulos V, Saluja AK, Kaiser AM, Nishino H, Gerdes D, Steer ML. Evaluation of necrotizing pancreatitis in the opossum by dynamic contrast-enhanced computed tomography: correlation between radiographic and morphologic changes. J Am Coll Surg. 1995 Jun; 180(6):673-82.
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  68. Fallon MB, Gorelick FS, Anderson JM, Mennone A, Saluja A, Steer ML. Effect of cerulein hyperstimulation on the paracellular barrier of rat exocrine pancreas. Gastroenterology. 1995 Jun; 108(6):1863-72.
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  69. Lerch MM, Saluja AK, Rünzi M, Dawra R, Steer ML. Luminal endocytosis and intracellular targeting by acinar cells during early biliary pancreatitis in the opossum. J Clin Invest. 1995 May; 95(5):2222-31.
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  70. Steer ML. Recent insights into the etiology and pathogenesis of acute biliary pancreatitis. AJR Am J Roentgenol. 1995 Apr; 164(4):811-4.
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  71. Glazer G, Coulter C, Crofton ME, Gedroyc WM, Johnson CD, Mallinson CN, Russell RC, Steer ML, Summerfield JA, Williamson RC. Controversial issues in the management of pancreatic cancer: Part one. A debate held at St Mary's Hospital, London on 18 November 1993. Ann R Coll Surg Engl. 1995 Mar; 77(2):111-22.
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  72. Baba Y, Lerch MM, Tanimoto A, Kreft BP, Saluja AK, Zhao L, Chen J, Steer ML, Stark DD. Enhancement of pancreas and diagnosis of pancreatitis using manganese dipyridoxyl diphosphate. Invest Radiol. 1994 Jun; 29 Suppl 2:S300-1.
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  73. Dawra RK, Saluja AK, Rünzi M, Steer ML. Inositol trisphosphate-independent agonist-stimulated calcium influx in rat pancreatic acinar cells. J Biol Chem. 1993 Sep 25; 268(27):20237-42.
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  74. Rünzi M, Saluja A, Lerch MM, Dawra R, Nishino H, Steer ML. Early ductal decompression prevents the progression of biliary pancreatitis: an experimental study in the opossum. Gastroenterology. 1993 Jul; 105(1):157-64.
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  75. Dawra R, Saluja A, Lerch MM, Saluja M, Logsdon C, Steer M. Stimulation of pancreatic growth by cholecystokinin is mediated by high affinity receptors on rat pancreatic acinar cells. Biochem Biophys Res Commun. 1993 Jun 30; 193(3):814-20.
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  76. Lerch MM, Saluja AK, Dawra R, Saluja M, Steer ML. The effect of chloroquine administration on two experimental models of acute pancreatitis. Gastroenterology. 1993 Jun; 104(6):1768-79.
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  77. Hirano T, Manabe T, Steer M, Printz H, Calne R, Tobe T. Protective effects of therapy with a protease and xanthine oxidase inhibitor in short form pancreatic biliary obstruction and ischemia in rats. Surg Gynecol Obstet. 1993 Apr; 176(4):371-81.
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  78. Lerch MM, Saluja AK, Rünzi M, Dawra R, Saluja M, Steer ML. Pancreatic duct obstruction triggers acute necrotizing pancreatitis in the opossum. Gastroenterology. 1993 Mar; 104(3):853-61.
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  79. Borum M, Steinberg W, Steer M, Freedman S, White P. Chronic pancreatitis: a complication of systemic lupus erythematosus. Gastroenterology. 1993 Feb; 104(2):613-5.
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  80. Steer ML. How and where does acute pancreatitis begin? Arch Surg. 1992 Nov; 127(11):1350-3.
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  81. Steer ML. Pathobiology of experimental acute pancreatitis. Yale J Biol Med. 1992 Sep-Oct; 65(5):421-30; discussion 437-40.
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  82. Hirano T, Manabe T, Saluja AK, Steer ML. Pancreatic secretion of lysosomal enzymes stimulated by intraduodenal instillation of a liquid meal in rabbits. Clin Sci (Lond). 1992 Sep; 83(3):277-80.
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  83. Lerch MM, Saluja AK, Dawra R, Ramaraò P, Saluja M, Steer ML. Acute necrotizing pancreatitis in the opossum: earliest morphological changes involve acinar cells. Gastroenterology. 1992 Jul; 103(1):205-13.
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  84. Grady T, Saluja AK, Steer ML, Lerch MM, Modlin IM, Powers RE. In vivo and in vitro effects of the azidothymidine analog dideoxyinosine on the exocrine pancreas of the rat. J Pharmacol Exp Ther. 1992 Jul; 262(1):445-9.
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  85. Saluja AK, Dawra RK, Lerch MM, Steer ML. CCK-JMV-180, an analog of cholecystokinin, releases intracellular calcium from an inositol trisphosphate-independent pool in rat pancreatic acini. J Biol Chem. 1992 Jun 5; 267(16):11202-7.
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  86. Hirano T, Manabe T, Printz H, Saluja A, Steer M. Secretion of lysosomal and digestive enzymes into pancreatic juice under physiological and pathological conditions in rabbits. Nihon Geka Hokan. 1992 Mar 1; 61(2):103-24.
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  87. Hirano T, Saluja A, Ramarao P, Lerch MM, Steer ML. Effects of chloroquine and methylamine on lysosomal enzyme secretion by rat pancreas. Am J Physiol. 1992 Mar; 262(3 Pt 1):G439-44.
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  88. Steer ML, Rutledge PL, Powers RE, Saluja M, Saluja AK. The role of oxygen-derived free radicals in two models of experimental acute pancreatitis: effects of catalase, superoxide dismutase, dimethylsulfoxide, and allopurinol. Klin Wochenschr. 1991 Dec 15; 69(21-23):1012-7.
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  89. Saluja M, Saluja A, Lerch MM, Steer ML. A plasma protease which is expressed during supramaximal stimulation causes in vitro subcellular redistribution of lysosomal enzymes in rat exocrine pancreas. J Clin Invest. 1991 Apr; 87(4):1280-5.
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  90. Hirano T, Saluja A, Ramarao P, Lerch MM, Saluja M, Steer ML. Apical secretion of lysosomal enzymes in rabbit pancreas occurs via a secretagogue regulated pathway and is increased after pancreatic duct obstruction. J Clin Invest. 1991 Mar; 87(3):865-9.
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  91. Ohshio G, Saluja A, Steer ML. Effects of short-term pancreatic duct obstruction in rats. Gastroenterology. 1991 Jan; 100(1):196-202.
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  92. Steer ML, Singer MV. A Rosetta Stone for chronic pancreatitis? Int J Pancreatol. 1990 Jun; 6(4):i-ii.
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  93. Kim D, Porter DH, Siegel JB, Mowschenson PM, Steer ML. Common bile duct biopsy with the Simpson atherectomy catheter. AJR Am J Roentgenol. 1990 Jun; 154(6):1213-5.
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  94. Leli U, Saluja A, Picard L, Zavertnik A, Steer ML. Effects of a choline-deficient ethionine-supplemented diet on phospholipase C activity in mouse pancreatic acinar cell membranes and in electropermeabilized mouse pancreatic acini. J Pharmacol Exp Ther. 1990 May; 253(2):847-50.
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  95. Printz H, Saluja A, Leli U, Sengupta A, Steer M. Effects of hemorrhagic shock, aspirin, and ethanol on secretagogue-induced experimental pancreatitis. Int J Pancreatol. 1990 Apr; 6(3):207-17.
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  96. Saluja AK, Saluja M, Printz H, Zavertnik A, Sengupta A, Steer ML. Experimental pancreatitis is mediated by low-affinity cholecystokinin receptors that inhibit digestive enzyme secretion. Proc Natl Acad Sci U S A. 1989 Nov; 86(22):8968-71.
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  97. Saluja AK, Powers RE, Steer ML. Inositol trisphosphate independent increase of intracellular free calcium and amylase secretion in pancreatic acini. Biochem Biophys Res Commun. 1989 Oct 16; 164(1):8-13.
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  98. Saluja A, Saluja M, Villa A, Leli U, Rutledge P, Meldolesi J, Steer M. Pancreatic duct obstruction in rabbits causes digestive zymogen and lysosomal enzyme colocalization. J Clin Invest. 1989 Oct; 84(4):1260-6.
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  99. Steer ML. Classification and pathogenesis of pancreatitis. Surg Clin North Am. 1989 Jun; 69(3):467-80.
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  100. Ohshio G, Saluja AK, Leli U, Sengupta A, Steer ML. Esterase inhibitors prevent lysosomal enzyme redistribution in two noninvasive models of experimental pancreatitis. Gastroenterology. 1989 Mar; 96(3):853-9.
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  101. Ohshio G, Saluja A, Leli U, Sengupta A, Steer ML. Failure of a potent cholecystokinin antagonist to protect against diet-induced pancreatitis in mice. Pancreas. 1989; 4(6):739-43.
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  102. Rutledge PL, Saluja A, Leli U, Steer ML. A simple and efficient method of measuring in vitro amylase secretion by dispersed pancreatic acini. Pancreas. 1988; 3(5):508-11.
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  103. Steer ML, Meldolesi J. Pathogenesis of acute pancreatitis. Annu Rev Med. 1988; 39:95-105.
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  104. Carter KJ, Rutledge PL, Steer ML, Silen W. Secretagogue-induced changes in intracellular pH and amylase release in mouse pancreatic acini. Am J Physiol. 1987 Nov; 253(5 Pt 1):G690-6.
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  105. Saluja A, Hashimoto S, Saluja M, Powers RE, Meldolesi J, Steer ML. Subcellular redistribution of lysosomal enzymes during caerulein-induced pancreatitis. Am J Physiol. 1987 Oct; 253(4 Pt 1):G508-16.
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  106. Saito I, Hashimoto S, Saluja A, Steer ML, Meldolesi J. Intracellular transport of pancreatic zymogens during caerulein supramaximal stimulation. Am J Physiol. 1987 Oct; 253(4 Pt 1):G517-26.
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  107. Kim D, Turkel DH, Orron DE, Steer ML. Percutaneous atheroma removal using a wire basket. AJR Am J Roentgenol. 1987 Sep; 149(3):625-8.
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  108. Rutledge PL, Saluja AK, Powers RE, Steer ML. Role of oxygen-derived free radicals in diet-induced hemorrhagic pancreatitis in mice. Gastroenterology. 1987 Jul; 93(1):41-7.
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  109. Alderman JD, Gabliani GI, McCabe CH, Brewer CC, Lorell BH, Pasternak RC, Skillman JJ, Steer ML, Baim DS. Incidence and management of limb ischemia with percutaneous wire-guided intraaortic balloon catheters. J Am Coll Cardiol. 1987 Mar; 9(3):524-30.
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  110. Steer ML, Meldolesi J. The cell biology of experimental pancreatitis. N Engl J Med. 1987 Jan 15; 316(3):144-50.
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  111. Powers RE, Saluja AK, Houlihan MJ, Steer ML. Diminished agonist-stimulated inositol trisphosphate generation blocks stimulus-secretion coupling in mouse pancreatic acini during diet-induced experimental pancreatitis. J Clin Invest. 1986 May; 77(5):1668-74.
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  112. Saluja A, Saluja M, Powers RE, Houlihan MJ, Steer ML. Failure of extracellular digestive enzymes to alter in vitro secretion by rat pancreas. Am J Physiol. 1986 Mar; 250(3 Pt 1):C413-7.
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  113. Saluja A, Saito I, Saluja M, Houlihan MJ, Powers RE, Meldolesi J, Steer M. In vivo rat pancreatic acinar cell function during supramaximal stimulation with caerulein. Am J Physiol. 1985 Dec; 249(6 Pt 1):G702-10.
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  114. Powers RE, Saluja AK, Houlihan MJ, Steer ML. Inositol trisphosphate production and amylase secretion in mouse pancreatic acini. Biochem Biophys Res Commun. 1985 Aug 30; 131(1):284-8.
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  115. Steer ML. Workshop on experimental pancreatitis. Dig Dis Sci. 1985 Jun; 30(6):575-81.
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  116. Powers RE, Johnson PC, Houlihan MJ, Saluja AK, Steer ML. Intracellular Ca2+ levels and amylase secretion in Quin 2-loaded mouse pancreatic acini. Am J Physiol. 1985 May; 248(5 Pt 1):C535-41.
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  117. Steer ML, Meldolesi J, Figarella C. Pancreatitis. The role of lysosomes. Dig Dis Sci. 1984 Oct; 29(10):934-8.
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  118. Lynch CJ, Guarino JJ, Deth RC, Steer ML. Effect of sucrose feeding on alpha 1-adrenergic responses in rat liver. Am J Physiol. 1984 Apr; 246(4 Pt 1):E344-9.
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  119. Steer ML. Search for the trigger mechanism of pancreatitis. Gastroenterology. 1984 Apr; 86(4):764-6.
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  120. MacIntyre DE, Hoover RL, Smith M, Steer M, Lynch C, Karnovsky MJ, Salzman EW. Inhibition of platelet function by cis-unsaturated fatty acids. Blood. 1984 Apr; 63(4):848-57.
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  121. Watanabe O, Baccino FM, Steer ML, Meldolesi J. Supramaximal caerulein stimulation and ultrastructure of rat pancreatic acinar cell: early morphological changes during development of experimental pancreatitis. Am J Physiol. 1984 Apr; 246(4 Pt 1):G457-67.
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  122. Steer ML, Silen W. Diagnostic procedures in gastrointestinal hemorrhage. N Engl J Med. 1983 Sep 15; 309(11):646-50.
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  123. Goldman LD, Steer ML, Silen W. Recurrent cholangitis after biliary surgery. Am J Surg. 1983 Apr; 145(4):450-4.
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  124. Trnka YM, Glotzer DJ, Kasdon EJ, Goldman H, Steer ML, Goldman LD. The long-term outcome of restorative operation in Crohn's disease: influence of location, prognostic factors and surgical guidelines. Ann Surg. 1982 Sep; 196(3):345-55.
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  125. Koike H, Steer ML, Meldolesi J. Pancreatic effects of ethionine: blockade of exocytosis and appearance of crinophagy and autophagy precede cellular necrosis. Am J Physiol. 1982 Apr; 242(4):G297-307.
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  126. Steer ML, Braun S, Lester HA, Levitzki A. Activation of adenylate cyclase from purified platelet membranes by prostaglandin E1 and its inhibition by L-epinephrine: mechanistic effects. J Cyclic Nucleotide Res. 1982; 8(5):309-22.
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  127. Gilliland EL, Turner N, Steer ML. The effects of ethionine administration and choline deficiency on protein carboxymethylase activity in mouse pancreas. Biochim Biophys Acta. 1981 Feb 5; 672(3):280-7.
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  128. Gilliland L, Steer ML. Effects of ethionine on digestive enzyme synthesis and discharge by mouse pancreas. Am J Physiol. 1980 Nov; 239(5):G418-26.
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  129. Dellinger EP, Kirshenbaum G, Weinstein M, Steer M. Determinants of adverse reaction following postoperative T-tube cholangiogram. Ann Surg. 1980 Apr; 191(4):397-403.
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  130. Manabe T, Steer ML. Protective effects of PGE2 on diet-induced acute pancreatitis in mice. Gastroenterology. 1980 Apr; 78(4):777-81.
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  131. Steer ML, Glotzer DJ. Colonic exclusion bypass principle: its use in the palliative treatment of malignant duodenocolic and gastrocolic fistulas. Arch Surg. 1980 Jan; 115(1):87-9.
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  132. Steer ML, Glazer G, Manabe T. Direct effects of ethanol on exocrine secretion from the in vitro rabbit pancreas. Dig Dis Sci. 1979 Oct; 24(10):769-74.
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  133. Manabe T, Steer ML. Effects of glucagon on pancreatic content and secretion of amylase in mice. Proc Soc Exp Biol Med. 1979 Sep; 161(4):538-42.
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  134. Steer ML, Manabe T. Cholecystokinin/pancreozymin induces the parallel discharge of digestive enzymes from the in vitro rabbit pancreas. J Biol Chem. 1979 Aug 10; 254(15):7228-9.
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  135. Manabe T, Steer ML. Protease inhibitors and experimental acute hemorrhagic pancreatitis. Ann Surg. 1979 Jul; 190(1):13-7.
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  136. Manabe T, Steer ML. Experimental acute pancreatitis in mice. Protective effects of glucagon. Gastroenterology. 1979 Mar; 76(3):529-34.
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  137. Manabe T, Steer ML. Diet-induced pancreatitis in mice: effect of glucagon on mortality and pancreatic function. Surg Forum. 1978; 29:454-6.
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  138. Glazer G, Steer ML. Requirements for activation of trypsinogen and chymotrypsinogen in rabbit pancreatic juice. Anal Biochem. 1977 Jan; 77(1):130-40.
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  139. Steer ML, Glazer G. Parallel secretion of digestive enzymes by the in vitro rabbit pancreas. Am J Physiol. 1976 Dec; 231(6):1860-5.
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  140. Sevilla N, Steer ML, Levitzki A. Synergistic activation of adenylate cyclase by guanylyl imidophosphate and epinephrine. Biochemistry. 1976 Aug 10; 15(16):3493-9.
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  141. Glazer G, Baldwin C, Steer M. Proceedings: The effect of ethanol on enzyme secretion from the rabbit pancreas in vitro. Br J Surg. 1976 Aug; 63(8):663.
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  142. Frank HA, Hall FM, Steer ML. Preoperative localization of nonpalpable breast lesions demonstrated by mammography. N Engl J Med. 1976 Jul 29; 295(5):259-60.
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  143. Steer ML. Cyclic AMP. Ann Surg. 1976 Jul; 184(1):107-15.
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  144. Glazer G, Silverman S, Steer M. Proceedings: Parallel secretion of amylase, tryposinogen and chymotrypsinogen from the in vitro rabbit pancreas. J Physiol. 1976 Jun; 258(2):88P-90P.
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  145. Eisenberg H, Steer ML. The nonoperative treatment of massive pyloroduodenal hemorrhage by retracted autologous clot embolization. Surgery. 1976 Apr; 79(4):414-20.
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  146. Levitzki A, Sevilla N, Steer ML. The regulatory control of beta-receptor dependent adenylate cyclase. J Supramol Struct. 1976; 4(3):405-18.
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  147. Bloom P, Steer ML. Pancreatoduodenectomy. Results when the operation is performed infrequently. Arch Surg. 1975 Dec; 110(12):1455-7.
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  148. Levitzki A, Sevilia N, Atlas D, Steer ML. Ligand specificity and characteristics of the beta-adrenergic receptor in turkey erythrocyte plasma membranes. J Mol Biol. 1975 Sep 5; 97(1):35-46.
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  149. Steer ML, Levitzki A. The control of adenylate cyclase by calcium in turkey erythrocyte ghosts. J Biol Chem. 1975 Mar 25; 250(6):2080-4.
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  150. Steer ML, Levitzki A. The interaction of catecholamines, Ca2+ and adenylate cyclase in the intact turkey erythrocyte. Arch Biochem Biophys. 1975 Mar; 167(1):371-6.
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  151. Steer ML, Atlas D, Levitzki A. Inter-relations between beta-adrenergic receptors, adenylate cyclase and calcium. N Engl J Med. 1975 Feb 20; 292(8):409-14.
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  152. Levitzki A, Steer ML. The allosteric activation of mammalian alpha-amylase by chloride. Eur J Biochem. 1974 Jan 3; 41(1):171-80.
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  153. Steer ML, Levitzki A. The metal specificity of mammalian -amylase as revealed by enzyme activity and structural probes. FEBS Lett. 1973 Apr 1; 31(1):89-92.
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  154. Steer ML, Spotnitz AJ, Cohen SI, Paulin S, Salzman EW. Limitations of impedance phlebography for diagnosis of venous thrombosis. Arch Surg. 1973 Jan; 106(1):44-8.
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  155. Turini P, Kurooka S, Steer M, Corbascio AN, Singer TP. The action of phenylmethylsulfonyl fluoride on human acetylcholinesterase, chymotyrpsin and trypsin. J Pharmacol Exp Ther. 1969 May; 167(1):98-104.
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