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Nan McKenzie Laird, Ph.D.

TitleHarvey V. Fineberg Professor of Public Health and Professor of Biostatistics
InstitutionHarvard School of Public Health
DepartmentBiostatistics
AddressHarvard School of Public Health
Bldg 2, 4th FL
655 Huntington Ave
Boston MA 02115
Phone617/432-4949

 Bibliographic 
 selected publications
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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  1. Zhou JJ, Cho MH, Castaldi PJ, Hersh CP, Silverman EK, Laird NM. Heritability of chronic obstructive pulmonary disease and related phenotypes in smokers. Am J Respir Crit Care Med. 2013 Oct 15; 188(8):941-7.
    View in: PubMed
  2. Moreno-Macías H, Dockery DW, Schwartz J, Gold DR, Laird NM, Sienra-Monge JJ, Del Río-Navarro BE, Ramírez-Aguilar M, Barraza-Villarreal A, Li H, London SJ, Romieu I. Ozone exposure, vitamin C intake, and genetic susceptibility of asthmatic children in Mexico City: a cohort study. Respir Res. 2013; 14:14.
    View in: PubMed
  3. De G, Yip WK, Ionita-Laza I, Laird N. Rare variant analysis for family-based design. PLoS One. 2013; 8(1):e48495.
    View in: PubMed
  4. Field AE, Sonneville KR, Micali N, Crosby RD, Swanson SA, Laird NM, Treasure J, Solmi F, Horton NJ. Prospective association of common eating disorders and adverse outcomes. Pediatrics. 2012 Aug; 130(2):e289-95.
    View in: PubMed
  5. Adhikari K, AlChawa T, Ludwig K, Mangold E, Laird N, Lange C. Is it rare or common? Genet Epidemiol. 2012 Jul; 36(5):419-29.
    View in: PubMed
  6. Yan A, Laird NM, Li C. Identifying rare variants using a Bayesian regression approach. BMC Proc. 2011; 5 Suppl 9:S99.
    View in: PubMed
  7. Sebro R, Lange C, Laird NM, Rogus JJ, Risch NJ. Differentiating population stratification from genotyping error using family data. Ann Hum Genet. 2012 Jan; 76(1):42-52.
    View in: PubMed
  8. Castaldi PJ, Cho MH, Litonjua AA, Bakke P, Gulsvik A, Lomas DA, Anderson W, Beaty TH, Hokanson JE, Crapo JD, Laird N, Silverman EK. The association of genome-wide significant spirometric loci with chronic obstructive pulmonary disease susceptibility. Am J Respir Cell Mol Biol. 2011 Dec; 45(6):1147-53.
    View in: PubMed
  9. Yoon FB, Fitzmaurice GM, Lipsitz SR, Horton NJ, Laird NM, Normand SL. Alternative methods for testing treatment effects on the basis of multiple outcomes: simulation and case study. Stat Med. 2011 Jul 20; 30(16):1917-32.
    View in: PubMed
  10. Javaras KN, Goldsmith HH, Laird NM. Estimating the effect of a predictor measured by two informants on a continuous outcome: a comparison of methods. Epidemiology. 2011 May; 22(3):390-9.
    View in: PubMed
  11. Howrigan DP, Laird NM, Smoller JW, Devlin B, McQueen MB. Using linkage information to weight a genome-wide association of bipolar disorder. Am J Med Genet B Neuropsychiatr Genet. 2011 Jun; 156B(4):462-71.
    View in: PubMed
  12. Hoffmann TJ, Vansteelandt S, Lange C, Silverman EK, DeMeo DL, Laird NM. Combining disease models to test for gene-environment interaction in nuclear families. Biometrics. 2011 Dec; 67(4):1260-70.
    View in: PubMed
  13. Ionita-Laza I, Buxbaum JD, Laird NM, Lange C. A new testing strategy to identify rare variants with either risk or protective effect on disease. PLoS Genet. 2011; 7(2):e1001289.
    View in: PubMed
  14. Sato Y, Yamamoto N, Kunitoh H, Ohe Y, Minami H, Laird NM, Katori N, Saito Y, Ohnami S, Sakamoto H, Sawada J, Saijo N, Yoshida T, Tamura T. Genome-wide association study on overall survival of advanced non-small cell lung cancer patients treated with carboplatin and paclitaxel. J Thorac Oncol. 2011 Jan; 6(1):132-8.
    View in: PubMed
  15. Ionita-Laza I, Laird NM. On the optimal design of genetic variant discovery studies. Stat Appl Genet Mol Biol. 2010; 9(1):Article33.
    View in: PubMed
  16. VanderWeele TJ, Laird NM. Tests for compositional epistasis under single interaction-parameter models. Ann Hum Genet. 2011 Jan; 75(1):146-56.
    View in: PubMed
  17. Moreno-Macias H, Romieu I, London SJ, Laird NM. Gene-environment interaction tests for family studies with quantitative phenotypes: A review and extension to longitudinal measures. Hum Genomics. 2010 Jun; 4(5):302-26.
    View in: PubMed
  18. Laird N, Fitzmaurice G, Ding X. Comments on 'Empirical vs natural weighting in random effects meta-analysis'. Stat Med. 2010 May 30; 29(12):1266-7; discussion 1272-81.
    View in: PubMed
  19. Javaras KN, Hudson JI, Laird NM. Fitting ACE structural equation models to case-control family data. Genet Epidemiol. 2010 Apr; 34(3):238-45.
    View in: PubMed
  20. Cho MH, Washko GR, Hoffmann TJ, Criner GJ, Hoffman EA, Martinez FJ, Laird N, Reilly JJ, Silverman EK. Cluster analysis in severe emphysema subjects using phenotype and genotype data: an exploratory investigation. Respir Res. 2010; 11:30.
    View in: PubMed
  21. Fan J, Ionita-Laza I, McQueen MB, Devlin B, Purcell S, Faraone SV, Allen MH, Bowden CL, Calabrese JR, Fossey MD, Friedman ES, Gyulai L, Hauser P, Ketter TB, Marangell LB, Miklowitz DJ, Nierenberg AA, Patel JK, Sachs GS, Thase ME, Molay FB, Escamilla MA, Nimgaonkar VL, Sklar P, Laird NM, Smoller JW. Linkage disequilibrium mapping of the chromosome 6q21-22.31 bipolar I disorder susceptibility locus. Am J Med Genet B Neuropsychiatr Genet. 2010 Jan 5; 153B(1):29-37.
    View in: PubMed
  22. Sato Y, Laird NM, Yoshida T. Biostatistic tools in pharmacogenomics--advances, challenges, potential. Curr Pharm Des. 2010; 16(20):2232-40.
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  23. Louicharoen C, Patin E, Paul R, Nuchprayoon I, Witoonpanich B, Peerapittayamongkol C, Casademont I, Sura T, Laird NM, Singhasivanon P, Quintana-Murci L, Sakuntabhai A. Positively selected G6PD-Mahidol mutation reduces Plasmodium vivax density in Southeast Asians. Science. 2009 Dec 11; 326(5959):1546-9.
    View in: PubMed
  24. Hoffmann TJ, Lange C, Vansteelandt S, Raby BA, DeMeo DL, Silverman EK, Weiss ST, Laird NM. Parsing the effects of individual SNPs in candidate genes with family data. Hum Hered. 2010; 69(2):91-103.
    View in: PubMed
  25. Hoffmann TJ, Lange C, Vansteelandt S, Laird NM. Gene-environment interaction tests for dichotomous traits in trios and sibships. Genet Epidemiol. 2009 Dec; 33(8):691-9.
    View in: PubMed
  26. Sato Y, Laird N, Suganami H, Hamada C, Niki N, Yoshimura I, Yoshida T. Statistical screening method for genetic factors influencing susceptibility to common diseases in a two-stage genome-wide association study. Stat Appl Genet Mol Biol. 2009; 8(1):Article 46.
    View in: PubMed
  27. Mansour HA, Talkowski ME, Wood J, Chowdari KV, McClain L, Prasad K, Montrose D, Fagiolini A, Friedman ES, Allen MH, Bowden CL, Calabrese J, El-Mallakh RS, Escamilla M, Faraone SV, Fossey MD, Gyulai L, Loftis JM, Hauser P, Ketter TA, Marangell LB, Miklowitz DJ, Nierenberg AA, Patel J, Sachs GS, Sklar P, Smoller JW, Laird N, Keshavan M, Thase ME, Axelson D, Birmaher B, Lewis D, Monk T, Frank E, Kupfer DJ, Devlin B, Nimgaonkar VL. Association study of 21 circadian genes with bipolar I disorder, schizoaffective disorder, and schizophrenia. Bipolar Disord. 2009 Nov; 11(7):701-10.
    View in: PubMed
  28. Heid IM, Huth C, Loos RJ, Kronenberg F, Adamkova V, Anand SS, Ardlie K, Biebermann H, Bjerregaard P, Boeing H, Bouchard C, Ciullo M, Cooper JA, Corella D, Dina C, Engert JC, Fisher E, Francès F, Froguel P, Hebebrand J, Hegele RA, Hinney A, Hoehe MR, Hu FB, Hubacek JA, Humphries SE, Hunt SC, Illig T, Järvelin MR, Kaakinen M, Kollerits B, Krude H, Kumar J, Lange LA, Langer B, Li S, Luchner A, Lyon HN, Meyre D, Mohlke KL, Mooser V, Nebel A, Nguyen TT, Paulweber B, Perusse L, Qi L, Rankinen T, Rosskopf D, Schreiber S, Sengupta S, Sorice R, Suk A, Thorleifsson G, Thorsteinsdottir U, Völzke H, Vimaleswaran KS, Wareham NJ, Waterworth D, Yusuf S, Lindgren C, McCarthy MI, Lange C, Hirschhorn JN, Laird N, Wichmann HE. Meta-analysis of the INSIG2 association with obesity including 74,345 individuals: does heterogeneity of estimates relate to study design? PLoS Genet. 2009 Oct; 5(10):e1000694.
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  29. Sangrajrang S, Sato Y, Sakamoto H, Ohnami S, Laird NM, Khuhaprema T, Brennan P, Boffetta P, Yoshida T. Genetic polymorphisms of estrogen metabolizing enzyme and breast cancer risk in Thai women. Int J Cancer. 2009 Aug 15; 125(4):837-43.
    View in: PubMed
  30. Javaras KN, Laird NM, Hudson JI, Ripley BD. Estimating disease prevalence using relatives of case and control probands. Biometrics. 2010 Mar; 66(1):214-21.
    View in: PubMed
  31. Ding X, Laird N. Family-Based Association Tests with longitudinal measurements: handling missing data. Hum Hered. 2009; 68(2):98-105.
    View in: PubMed
  32. Ding X, Weiss S, Raby B, Lange C, Laird NM. Impact of population stratification on family-based association tests with longitudinal measurements. Stat Appl Genet Mol Biol. 2009; 8(1):Article 17.
    View in: PubMed
  33. Murphy JM, Horton NJ, Burke JD, Monson RR, Laird NM, Lesage A, Sobol AM. Obesity and weight gain in relation to depression: findings from the Stirling County Study. Int J Obes (Lond). 2009 Mar; 33(3):335-41.
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  34. Sato Y, Laird NM, Nagashima K, Kato R, Hamano T, Yafune A, Kaniwa N, Saito Y, Sugiyama E, Kim SR, Furuse J, Ishii H, Ueno H, Okusaka T, Saijo N, Sawada JI, Yoshida T. A new statistical screening approach for finding pharmacokinetics-related genes in genome-wide studies. Pharmacogenomics J. 2009 Apr; 9(2):137-46.
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  35. Lasky-Su J, Anney RJ, Neale BM, Franke B, Zhou K, Maller JB, Vasquez AA, Chen W, Asherson P, Buitelaar J, Banaschewski T, Ebstein R, Gill M, Miranda A, Mulas F, Oades RD, Roeyers H, Rothenberger A, Sergeant J, Sonuga-Barke E, Steinhausen HC, Taylor E, Daly M, Laird N, Lange C, Faraone SV. Genome-wide association scan of the time to onset of attention deficit hyperactivity disorder. Am J Med Genet B Neuropsychiatr Genet. 2008 Dec 5; 147B(8):1355-8.
    View in: PubMed
  36. Neale BM, Lasky-Su J, Anney R, Franke B, Zhou K, Maller JB, Vasquez AA, Asherson P, Chen W, Banaschewski T, Buitelaar J, Ebstein R, Gill M, Miranda A, Oades RD, Roeyers H, Rothenberger A, Sergeant J, Steinhausen HC, Sonuga-Barke E, Mulas F, Taylor E, Laird N, Lange C, Daly M, Faraone SV. Genome-wide association scan of attention deficit hyperactivity disorder. Am J Med Genet B Neuropsychiatr Genet. 2008 Dec 5; 147B(8):1337-44.
    View in: PubMed
  37. Lasky-Su J, Neale BM, Franke B, Anney RJ, Zhou K, Maller JB, Vasquez AA, Chen W, Asherson P, Buitelaar J, Banaschewski T, Ebstein R, Gill M, Miranda A, Mulas F, Oades RD, Roeyers H, Rothenberger A, Sergeant J, Sonuga-Barke E, Steinhausen HC, Taylor E, Daly M, Laird N, Lange C, Faraone SV. Genome-wide association scan of quantitative traits for attention deficit hyperactivity disorder identifies novel associations and confirms candidate gene associations. Am J Med Genet B Neuropsychiatr Genet. 2008 Dec 5; 147B(8):1345-54.
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  38. Bertram L, Lange C, Mullin K, Parkinson M, Hsiao M, Hogan MF, Schjeide BM, Hooli B, Divito J, Ionita I, Jiang H, Laird N, Moscarillo T, Ohlsen KL, Elliott K, Wang X, Hu-Lince D, Ryder M, Murphy A, Wagner SL, Blacker D, Becker KD, Tanzi RE. Genome-wide association analysis reveals putative Alzheimer's disease susceptibility loci in addition to APOE. Am J Hum Genet. 2008 Nov; 83(5):623-32.
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  39. Ding X, Lange C, Xu X, Laird N. New powerful approaches for family-based association tests with longitudinal measurements. Ann Hum Genet. 2009 Jan; 73(1):74-83.
    View in: PubMed
  40. Ionita-Laza I, Laird NM, Raby BA, Weiss ST, Lange C. On the frequency of copy number variants. Bioinformatics. 2008 Oct 15; 24(20):2350-5.
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  41. Field AE, Javaras KM, Aneja P, Kitos N, Camargo CA, Taylor CB, Laird NM. Family, peer, and media predictors of becoming eating disordered. Arch Pediatr Adolesc Med. 2008 Jun; 162(6):574-9.
    View in: PubMed
  42. Hudson JI, Javaras KN, Laird NM, VanderWeele TJ, Pope HG, Hernán MA. A structural approach to the familial coaggregation of disorders. Epidemiology. 2008 May; 19(3):431-9.
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  43. Ionita-Laza I, Perry GH, Raby BA, Klanderman B, Lee C, Laird NM, Weiss ST, Lange C. On the analysis of copy-number variations in genome-wide association studies: a translation of the family-based association test. Genet Epidemiol. 2008 Apr; 32(3):273-84.
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  44. Lasky-Su J, Lyon HN, Emilsson V, Heid IM, Molony C, Raby BA, Lazarus R, Klanderman B, Soto-Quiros ME, Avila L, Silverman EK, Thorleifsson G, Thorsteinsdottir U, Kronenberg F, Vollmert C, Illig T, Fox CS, Levy D, Laird N, Ding X, McQueen MB, Butler J, Ardlie K, Papoutsakis C, Dedoussis G, O'Donnell CJ, Wichmann HE, Celedón JC, Schadt E, Hirschhorn J, Weiss ST, Stefansson K, Lange C. On the replication of genetic associations: timing can be everything! Am J Hum Genet. 2008 Apr; 82(4):849-58.
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  45. Rakovski CS, Weiss ST, Laird NM, Lange C. FBAT-SNP-PC: an approach for multiple markers and single trait in family-based association tests. Hum Hered. 2008; 66(2):122-6.
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  46. Murphy JM, Burke JD, Monson RR, Horton NJ, Laird NM, Lesage A, Sobol AM, Leighton AH. Mortality associated with depression: a forty-year perspective from the Stirling County Study. Soc Psychiatry Psychiatr Epidemiol. 2008 Aug; 43(8):594-601.
    View in: PubMed
  47. Javaras KN, Laird NM, Reichborn-Kjennerud T, Bulik CM, Pope HG, Hudson JI. Familiality and heritability of binge eating disorder: results of a case-control family study and a twin study. Int J Eat Disord. 2008 Mar; 41(2):174-9.
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  48. Javaras KN, Pope HG, Lalonde JK, Roberts JL, Nillni YI, Laird NM, Bulik CM, Crow SJ, McElroy SL, Walsh BT, Tsuang MT, Rosenthal NR, Hudson JI. Co-occurrence of binge eating disorder with psychiatric and medical disorders. J Clin Psychiatry. 2008 Feb; 69(2):266-73.
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  49. Lasky-Su J, Lange C, Biederman J, Tsuang M, Doyle AE, Smoller JW, Laird N, Faraone S. Family-based association analysis of a statistically derived quantitative traits for ADHD reveal an association in DRD4 with inattentive symptoms in ADHD individuals. Am J Med Genet B Neuropsychiatr Genet. 2008 Jan 5; 147B(1):100-6.
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  50. Laird NM, Lange C. Family-based methods for linkage and association analysis. Adv Genet. 2008; 60:219-52.
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  51. Schneiter K, Degnan JH, Corcoran C, Xu X, Laird N. EFBAT: exact family-based association tests. BMC Genet. 2007; 8:86.
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  52. Ionita-Laza I, McQueen MB, Laird NM, Lange C. Genomewide weighted hypothesis testing in family-based association studies, with an application to a 100K scan. Am J Hum Genet. 2007 Sep; 81(3):607-14.
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  53. Lasky-Su J, Biederman J, Laird N, Tsuang M, Doyle AE, Smoller JW, Lange C, Faraone SV. Evidence for an association of the dopamine D5 receptor gene on age at onset of attention deficit hyperactivity disorder. Ann Hum Genet. 2007 Sep; 71(Pt 5):648-59.
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  54. Harezlak J, Naumova E, Laird NM. LongCriSP: a test for bump hunting in longitudinal data. Stat Med. 2007 Mar 15; 26(6):1383-97.
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  55. Lyon HN, Emilsson V, Hinney A, Heid IM, Lasky-Su J, Zhu X, Thorleifsson G, Gunnarsdottir S, Walters GB, Thorsteinsdottir U, Kong A, Gulcher J, Nguyen TT, Scherag A, Pfeufer A, Meitinger T, Brönner G, Rief W, Soto-Quiros ME, Avila L, Klanderman B, Raby BA, Silverman EK, Weiss ST, Laird N, Ding X, Groop L, Tuomi T, Isomaa B, Bengtsson K, Butler JL, Cooper RS, Fox CS, O'Donnell CJ, Vollmert C, Celedón JC, Wichmann HE, Hebebrand J, Stefansson K, Lange C, Hirschhorn JN. The association of a SNP upstream of INSIG2 with body mass index is reproduced in several but not all cohorts. PLoS Genet. 2007 Apr 27; 3(4):e61.
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  56. McQueen MB, Weiss S, Laird NM, Lange C. On the parsing of statistical information in family-based association testing. Nat Genet. 2007 Mar; 39(3):281-2.
    View in: PubMed
  57. Litman HJ, Horton NJ, Hernández B, Laird NM. Incorporating missingness for estimation of marginal regression models with multiple source predictors. Stat Med. 2007 Feb 28; 26(5):1055-68.
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  58. Lasky-Su J, Faraone SV, Lange C, Tsuang MT, Doyle AE, Smoller JW, Laird NM, Biederman J. A study of how socioeconomic status moderates the relationship between SNPs encompassing BDNF and ADHD symptom counts in ADHD families. Behav Genet. 2007 May; 37(3):487-97.
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  59. Rakovski CS, Xu X, Lazarus R, Blacker D, Laird NM. A new multimarker test for family-based association studies. Genet Epidemiol. 2007 Jan; 31(1):9-17.
    View in: PubMed
  60. Van Steen K, Laird NM, Markel P, Molenberghs G. Approaches to handling incomplete data in family-based association testing. Ann Hum Genet. 2007 Mar; 71(Pt 2):141-51.
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  61. Xu X, Rakovski C, Xu X, Laird N. An efficient family-based association test using multiple markers. Genet Epidemiol. 2006 Nov; 30(7):620-6.
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  62. Litman HJ, Horton NJ, Murphy JM, Laird NM. Marginal regression models with a time to event outcome and discrete multiple source predictors. Lifetime Data Anal. 2006 Sep; 12(3):249-65.
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  63. Laird NM, Lange C. Family-based designs in the age of large-scale gene-association studies. Nat Rev Genet. 2006 May; 7(5):385-94.
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  64. Herbert A, Gerry NP, McQueen MB, Heid IM, Pfeufer A, Illig T, Wichmann HE, Meitinger T, Hunter D, Hu FB, Colditz G, Hinney A, Hebebrand J, Koberwitz K, Zhu X, Cooper R, Ardlie K, Lyon H, Hirschhorn JN, Laird NM, Lenburg ME, Lange C, Christman MF. A common genetic variant is associated with adult and childhood obesity. Science. 2006 Apr 14; 312(5771):279-83.
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  65. McQueen MB, Blacker D, Laird NM. Variance calculations for identity-by-descent estimation. Am J Hum Genet. 2006 Jun; 78(6):914-21.
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  66. Wang L, Wang X, Laird N, Zuckerman B, Stubblefield P, Xu X. Polymorphism in maternal LRP8 gene is associated with fetal growth. Am J Hum Genet. 2006 May; 78(5):770-7.
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  67. Hudson JI, Lalonde JK, Berry JM, Pindyck LJ, Bulik CM, Crow SJ, McElroy SL, Laird NM, Tsuang MT, Walsh BT, Rosenthal NR, Pope HG. Binge-eating disorder as a distinct familial phenotype in obese individuals. Arch Gen Psychiatry. 2006 Mar; 63(3):313-9.
    View in: PubMed
  68. Hsu YH, Venners SA, Terwedow HA, Feng Y, Niu T, Li Z, Laird N, Brain JD, Cummings SR, Bouxsein ML, Rosen CJ, Xu X. Relation of body composition, fat mass, and serum lipids to osteoporotic fractures and bone mineral density in Chinese men and women. Am J Clin Nutr. 2006 Jan; 83(1):146-54.
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  69. McQueen MB, Murphy A, Kraft P, Su J, Lazarus R, Laird NM, Lange C, Van Steen K. Comparison of linkage and association strategies for quantitative traits using the COGA dataset. BMC Genet. 2005; 6 Suppl 1:S96.
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  70. Murphy A, McQueen MB, Su J, Kraft P, Lazarus R, Laird NM, Lange C, Van Steen K. Genomic screening in family-based association testing. BMC Genet. 2005; 6 Suppl 1:S115.
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  71. Field AE, Austin SB, Striegel-Moore R, Taylor CB, Camargo CA, Laird N, Colditz G. Weight concerns and weight control behaviors of adolescents and their mothers. Arch Pediatr Adolesc Med. 2005 Dec; 159(12):1121-6.
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  72. Schneiter K, Laird N, Corcoran C. Exact family-based association tests for biallelic data. Genet Epidemiol. 2005 Nov; 29(3):185-94.
    View in: PubMed
  73. Hsu YH, Niu T, Terwedow HA, Xu X, Feng Y, Li Z, Brain JD, Rosen CJ, Laird N, Xu X. Variation in genes involved in the RANKL/RANK/OPG bone remodeling pathway are associated with bone mineral density at different skeletal sites in men. Hum Genet. 2006 Jan; 118(5):568-77.
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  74. McQueen MB, Devlin B, Faraone SV, Nimgaonkar VL, Sklar P, Smoller JW, Abou Jamra R, Albus M, Bacanu SA, Baron M, Barrett TB, Berrettini W, Blacker D, Byerley W, Cichon S, Coryell W, Craddock N, Daly MJ, Depaulo JR, Edenberg HJ, Foroud T, Gill M, Gilliam TC, Hamshere M, Jones I, Jones L, Juo SH, Kelsoe JR, Lambert D, Lange C, Lerer B, Liu J, Maier W, Mackinnon JD, McInnis MG, McMahon FJ, Murphy DL, Nothen MM, Nurnberger JI, Pato CN, Pato MT, Potash JB, Propping P, Pulver AE, Rice JP, Rietschel M, Scheftner W, Schumacher J, Segurado R, Van Steen K, Xie W, Zandi PP, Laird NM. Combined analysis from eleven linkage studies of bipolar disorder provides strong evidence of susceptibility loci on chromosomes 6q and 8q. Am J Hum Genet. 2005 Oct; 77(4):582-95.
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  75. Smoller JW, Yamaki LH, Fagerness JA, Biederman J, Racette S, Laird NM, Kagan J, Snidman N, Faraone SV, Hirshfeld-Becker D, Tsuang MT, Slaugenhaupt SA, Rosenbaum JF, Sklar PB. The corticotropin-releasing hormone gene and behavioral inhibition in children at risk for panic disorder. Biol Psychiatry. 2005 Jun 15; 57(12):1485-92.
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  76. Van Steen K, McQueen MB, Herbert A, Raby B, Lyon H, Demeo DL, Murphy A, Su J, Datta S, Rosenow C, Christman M, Silverman EK, Laird NM, Weiss ST, Lange C. Genomic screening and replication using the same data set in family-based association testing. Nat Genet. 2005 Jul; 37(7):683-91.
    View in: PubMed
  77. Hersh CP, Demeo DL, Lange C, Litonjua AA, Reilly JJ, Kwiatkowski D, Laird N, Sylvia JS, Sparrow D, Speizer FE, Weiss ST, Silverman EK. Attempted replication of reported chronic obstructive pulmonary disease candidate gene associations. Am J Respir Cell Mol Biol. 2005 Jul; 33(1):71-8.
    View in: PubMed
  78. Abecasis G, Cox N, Daly MJ, Kruglyak L, Laird N, Markianos K, Patterson N. No bias in linkage analysis. Am J Hum Genet. 2004 Oct; 75(4):722-3; author reply 723-7.
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  79. Lange C, van Steen K, Andrew T, Lyon H, DeMeo DL, Raby B, Murphy A, Silverman EK, MacGregor A, Weiss ST, Laird NM. A family-based association test for repeatedly measured quantitative traits adjusting for unknown environmental and/or polygenic effects. Stat Appl Genet Mol Biol. 2004; 3:Article17.
    View in: PubMed
  80. Celedón JC, Lange C, Raby BA, Litonjua AA, Palmer LJ, DeMeo DL, Reilly JJ, Kwiatkowski DJ, Chapman HA, Laird N, Sylvia JS, Hernandez M, Speizer FE, Weiss ST, Silverman EK. The transforming growth factor-beta1 (TGFB1) gene is associated with chronic obstructive pulmonary disease (COPD). Hum Mol Genet. 2004 Aug 1; 13(15):1649-56.
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  81. Feng Y, Niu T, Xing H, Xu X, Chen C, Peng S, Wang L, Laird N, Xu X. A common haplotype of the nicotine acetylcholine receptor alpha 4 subunit gene is associated with vulnerability to nicotine addiction in men. Am J Hum Genet. 2004 Jul; 75(1):112-21.
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  82. Murphy JM, Horton NJ, Laird NM, Monson RR, Sobol AM, Leighton AH. Anxiety and depression: a 40-year perspective on relationships regarding prevalence, distribution, and comorbidity. Acta Psychiatr Scand. 2004 May; 109(5):355-75.
    View in: PubMed
  83. Brennan TA, Leape LL, Laird NM, Hebert L, Localio AR, Lawthers AG, Newhouse JP, Weiler PC, Hiatt HH. Incidence of adverse events and negligence in hospitalized patients: results of the Harvard Medical Practice Study I. 1991. Qual Saf Health Care. 2004 Apr; 13(2):145-51; discussion 151-2.
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  84. Hao K, Wang X, Niu T, Xu X, Li A, Chang W, Wang L, Li G, Laird N, Xu X. A candidate gene association study on preterm delivery: application of high-throughput genotyping technology and advanced statistical methods. Hum Mol Genet. 2004 Apr 1; 13(7):683-91.
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  85. Field AE, Manson JE, Laird N, Williamson DF, Willett WC, Colditz GA. Weight cycling and the risk of developing type 2 diabetes among adult women in the United States. Obes Res. 2004 Feb; 12(2):267-74.
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  86. Lyon H, Lange C, Lake S, Silverman EK, Randolph AG, Kwiatkowski D, Raby BA, Lazarus R, Weiland KM, Laird N, Weiss ST. IL10 gene polymorphisms are associated with asthma phenotypes in children. Genet Epidemiol. 2004 Feb; 26(2):155-65.
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  87. Lange C, DeMeo D, Silverman EK, Weiss ST, Laird NM. PBAT: tools for family-based association studies. Am J Hum Genet. 2004 Feb; 74(2):367-9.
    View in: PubMed
  88. Lange C, Blacker D, Laird NM. Family-based association tests for survival and times-to-onset analysis. Stat Med. 2004 Jan 30; 23(2):179-89.
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  89. Lake SL, Laird NM. Tests of gene-environment interaction for case-parent triads with general environmental exposures. Ann Hum Genet. 2004 Jan; 68(Pt 1):55-64.
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  90. Horvath S, Xu X, Lake SL, Silverman EK, Weiss ST, Laird NM. Family-based tests for associating haplotypes with general phenotype data: application to asthma genetics. Genet Epidemiol. 2004 Jan; 26(1):61-9.
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  91. Hao K, Xu X, Laird N, Wang X, Xu X. Power estimation of multiple SNP association test of case-control study and application. Genet Epidemiol. 2004 Jan; 26(1):22-30.
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  92. Smoller JW, Rosenbaum JF, Biederman J, Kennedy J, Dai D, Racette SR, Laird NM, Kagan J, Snidman N, Hirshfeld-Becker D, Tsuang MT, Sklar PB, Slaugenhaupt SA. Association of a genetic marker at the corticotropin-releasing hormone locus with behavioral inhibition. Biol Psychiatry. 2003 Dec 15; 54(12):1376-81.
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  93. Silverman EK, Kwiatkowski DJ, Sylvia JS, Lazarus R, Drazen JM, Lange C, Laird NM, Weiss ST. Family-based association analysis of beta2-adrenergic receptor polymorphisms in the childhood asthma management program. J Allergy Clin Immunol. 2003 Nov; 112(5):870-6.
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  94. Field AE, Laird N, Steinberg E, Fallon E, Semega-Janneh M, Yanovski JA. Which metric of relative weight best captures body fatness in children? Obes Res. 2003 Nov; 11(11):1345-52.
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  95. Mangweth B, Hudson JI, Pope HG, Hausmann A, De Col C, Laird NM, Beibl W, Tsuang MT. Family study of the aggregation of eating disorders and mood disorders. Psychol Med. 2003 Oct; 33(7):1319-23.
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  96. Lange C, DeMeo D, Silverman EK, Weiss ST, Laird NM. Using the noninformative families in family-based association tests: a powerful new testing strategy. Am J Hum Genet. 2003 Oct; 73(4):801-11.
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  97. Saunders AJ, Bertram L, Mullin K, Sampson AJ, Latifzai K, Basu S, Jones J, Kinney D, MacKenzie-Ingano L, Yu S, Albert MS, Moscarillo TJ, Go RC, Bassett SS, Daly MJ, Laird NM, Wang X, Velicelebi G, Wagner SL, Becker DK, Tanzi RE, Blacker D. Genetic association of Alzheimer's disease with multiple polymorphisms in alpha-2-macroglobulin. Hum Mol Genet. 2003 Nov 1; 12(21):2765-76.
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  98. Murphy JM, Horton NJ, Monson RR, Laird NM, Sobol AM, Leighton AH. Cigarette smoking in relation to depression: historical trends from the Stirling County Study. Am J Psychiatry. 2003 Sep; 160(9):1663-9.
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  99. Slasor P, Laird N. Joint models for efficient estimation in proportional hazards regression models. Stat Med. 2003 Jul 15; 22(13):2137-48.
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  100. Laird NM, Cuenco KT. Regression methods for assessing familial aggregation of disease. Stat Med. 2003 May 15; 22(9):1447-55.
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  101. Yang Q, Xu X, Laird N. Power evaluations for family-based tests of association with incomplete parental genotypes. Genetics. 2003 May; 164(1):399-406.
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  102. Lange C, Silverman EK, Xu X, Weiss ST, Laird NM. A multivariate family-based association test using generalized estimating equations: FBAT-GEE. Biostatistics. 2003 Apr; 4(2):195-206.
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  103. Hudson JI, Mangweth B, Pope HG, De Col C, Hausmann A, Gutweniger S, Laird NM, Biebl W, Tsuang MT. Family study of affective spectrum disorder. Arch Gen Psychiatry. 2003 Feb; 60(2):170-7.
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  104. Lake SL, Lyon H, Tantisira K, Silverman EK, Weiss ST, Laird NM, Schaid DJ. Estimation and tests of haplotype-environment interaction when linkage phase is ambiguous. Hum Hered. 2003; 55(1):56-65.
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  105. Lange C, DeMeo DL, Laird NM. Power and design considerations for a general class of family-based association tests: quantitative traits. Am J Hum Genet. 2002 Dec; 71(6):1330-41.
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  106. DeMeo DL, Lange C, Silverman EK, Senter JM, Drazen JM, Barth MJ, Laird N, Weiss ST. Univariate and multivariate family-based association analysis of the IL-13 ARG130GLN polymorphism in the Childhood Asthma Management Program. Genet Epidemiol. 2002 Nov; 23(4):335-48.
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  107. Lange C, Laird NM. Power calculations for a general class of family-based association tests: dichotomous traits. Am J Hum Genet. 2002 Sep; 71(3):575-84.
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  108. Lange C, Laird NM. On a general class of conditional tests for family-based association studies in genetics: the asymptotic distribution, the conditional power, and optimality considerations. Genet Epidemiol. 2002 Aug; 23(2):165-80.
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  109. Murphy JM, Nierenberg AA, Laird NM, Monson RR, Sobol AM, Leighton AH. Incidence of major depression: prediction from subthreshold categories in the Stirling County Study. J Affect Disord. 2002 Apr; 68(2-3):251-9.
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  110. Pauler DK, Laird NM. Non-linear hierarchical models for monitoring compliance. Stat Med. 2002 Jan 30; 21(2):219-29.
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  111. Murphy JM, Nierenberg AA, Monson RR, Laird NM, Sobol AM, Leighton AH. Self-disparagement as feature and forerunner of depression: findings from the Stirling County Study. Compr Psychiatry. 2002 Jan-Feb; 43(1):13-21.
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  112. Daskalakis C, Laird NM, Murphy JM. Regression analysis of multiple-source longitudinal outcomes: a "Stirling County" depression study. Am J Epidemiol. 2002 Jan 1; 155(1):88-94.
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  113. Naumova EN, Must A, Laird NM. Tutorial in Biostatistics: Evaluating the impact of 'critical periods' in longitudinal studies of growth using piecewise mixed effects models. Int J Epidemiol. 2001 Dec; 30(6):1332-41.
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  114. Horton NJ, Laird NM, Murphy JM, Monson RR, Sobol AM, Leighton AH. Multiple informants: mortality associated with psychiatric disorders in the Stirling County Study. Am J Epidemiol. 2001 Oct 1; 154(7):649-56.
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  115. Field AE, Coakley EH, Must A, Spadano JL, Laird N, Dietz WH, Rimm E, Colditz GA. Impact of overweight on the risk of developing common chronic diseases during a 10-year period. Arch Intern Med. 2001 Jul 9; 161(13):1581-6.
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  116. Fitzmaurice GM, Laird NM, Shneyer L. An alternative parameterization of the general linear mixture model for longitudinal data with non-ignorable drop-outs. Stat Med. 2001 Apr 15; 20(7):1009-21.
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  117. Smoller JW, Rosenbaum JF, Biederman J, Susswein LS, Kennedy J, Kagan J, Snidman N, Laird N, Tsuang MT, Faraone SV, Schwarz A, Slaugenhaupt SA. Genetic association analysis of behavioral inhibition using candidate loci from mouse models. Am J Med Genet. 2001 Apr 8; 105(3):226-35.
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  118. Horvath S, Xu X, Laird NM. The family based association test method: strategies for studying general genotype--phenotype associations. Eur J Hum Genet. 2001 Apr; 9(4):301-6.
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  119. Hudson JI, Laird NM, Betensky RA, Keck PE, Pope HG. Multivariate logistic regression for familial aggregation of two disorders. II. Analysis of studies of eating and mood disorders. Am J Epidemiol. 2001 Mar 1; 153(5):506-14.
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  120. Horton NJ, Laird NM. Maximum likelihood analysis of logistic regression models with incomplete covariate data and auxiliary information. Biometrics. 2001 Mar; 57(1):34-42.
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  121. Hudson JI, Laird NM, Betensky RA. Multivariate logistic regression for familial aggregation of two disorders. I. Development of models and methods. Am J Epidemiol. 2001 Mar 1; 153(5):500-5.
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  122. Lake SL, Blacker D, Laird NM. Family-based tests of association in the presence of linkage. Am J Hum Genet. 2000 Dec; 67(6):1515-25.
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  123. Rabinowitz D, Laird N. A unified approach to adjusting association tests for population admixture with arbitrary pedigree structure and arbitrary missing marker information. Hum Hered. 2000 Jul-Aug; 50(4):211-23.
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  124. Hernández B, Gortmaker SL, Laird NM, Colditz GA, Parra-Cabrera S, Peterson KE. [Validity and reproducibility of a questionnaire on physical activity and non-activity for school children in Mexico City]. Salud Publica Mex. 2000 Jul-Aug; 42(4):315-23.
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  125. Pauler DK, Laird NM. A mixture model for longitudinal data with application to assessment of noncompliance. Biometrics. 2000 Jun; 56(2):464-72.
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  126. Murphy JM, Laird NM, Monson RR, Sobol AM, Leighton AH. Incidence of depression in the Stirling County Study: historical and comparative perspectives. Psychol Med. 2000 May; 30(3):505-14.
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  127. Murphy JM, Laird NM, Monson RR, Sobol AM, Leighton AH. A 40-year perspective on the prevalence of depression: the Stirling County Study. Arch Gen Psychiatry. 2000 Mar; 57(3):209-15.
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  128. Horvath S, Laird NM, Knapp M. The transmission/disequilibrium test and parental-genotype reconstruction for X-chromosomal markers. Am J Hum Genet. 2000 Mar; 66(3):1161-7.
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  129. Murphy JM, Monson RR, Laird NM, Sobol AM, Leighton AH. A comparison of diagnostic interviews for depression in the Stirling County study: challenges for psychiatric epidemiology. Arch Gen Psychiatry. 2000 Mar; 57(3):230-6.
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  130. Lunetta KL, Faraone SV, Biederman J, Laird NM. Family-based tests of association and linkage that use unaffected sibs, covariates, and interactions. Am J Hum Genet. 2000 Feb; 66(2):605-14.
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  131. Laird NM, Horvath S, Xu X. Implementing a unified approach to family-based tests of association. Genet Epidemiol. 2000; 19 Suppl 1:S36-42.
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  132. Bates DW, Miller EB, Cullen DJ, Burdick L, Williams L, Laird N, Petersen LA, Small SD, Sweitzer BJ, Vander Vliet M, Leape LL. Patient risk factors for adverse drug events in hospitalized patients. ADE Prevention Study Group. Arch Intern Med. 1999 Nov 22; 159(21):2553-60.
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  133. Korhonen PA, Laird NM, Palmgren J. Correcting for non-compliance in randomized trials: an application to the ATBC Study. Stat Med. 1999 Nov 15; 18(21):2879-97.
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  134. Field AE, Byers T, Hunter DJ, Laird NM, Manson JE, Williamson DF, Willett WC, Colditz GA. Weight cycling, weight gain, and risk of hypertension in women. Am J Epidemiol. 1999 Sep 15; 150(6):573-9.
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  135. Gortmaker SL, Cheung LW, Peterson KE, Chomitz G, Cradle JH, Dart H, Fox MK, Bullock RB, Sobol AM, Colditz G, Field AE, Laird N. Impact of a school-based interdisciplinary intervention on diet and physical activity among urban primary school children: eat well and keep moving. Arch Pediatr Adolesc Med. 1999 Sep; 153(9):975-83.
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  136. Hernández B, Gortmaker SL, Colditz GA, Peterson KE, Laird NM, Parra-Cabrera S. Association of obesity with physical activity, television programs and other forms of video viewing among children in Mexico city. Int J Obes Relat Metab Disord. 1999 Aug; 23(8):845-54.
    View in: PubMed
  137. Gortmaker SL, Peterson K, Wiecha J, Sobol AM, Dixit S, Fox MK, Laird N. Reducing obesity via a school-based interdisciplinary intervention among youth: Planet Health. Arch Pediatr Adolesc Med. 1999 Apr; 153(4):409-18.
    View in: PubMed
  138. Horton NJ, Laird NM. Maximum likelihood analysis of generalized linear models with missing covariates. Stat Methods Med Res. 1999 Mar; 8(1):37-50.
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  139. Niu T, Yang J, Wang B, Chen W, Wang Z, Laird N, Wei E, Fang Z, Lindpaintner K, Rogus JJ, Xu X. Angiotensinogen gene polymorphisms M235T/T174M: no excess transmission to hypertensive Chinese. Hypertension. 1999 Feb; 33(2):698-702.
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  140. Horvath S, Laird NM. A discordant-sibship test for disequilibrium and linkage: no need for parental data. Am J Hum Genet. 1998 Dec; 63(6):1886-97.
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  141. Laird NM, Blacker D, Wilcox M. The sib transmission/disequilibrium test is a Mantel-Haenszel test. Am J Hum Genet. 1998 Dec; 63(6):1915-6.
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  142. Bates DW, Leape LL, Cullen DJ, Laird N, Petersen LA, Teich JM, Burdick E, Hickey M, Kleefield S, Shea B, Vander Vliet M, Seger DL. Effect of computerized physician order entry and a team intervention on prevention of serious medication errors. JAMA. 1998 Oct 21; 280(15):1311-6.
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  143. Blacker D, Wilcox MA, Laird NM, Rodes L, Horvath SM, Go RC, Perry R, Watson B, Bassett SS, McInnis MG, Albert MS, Hyman BT, Tanzi RE. Alpha-2 macroglobulin is genetically associated with Alzheimer disease. Nat Genet. 1998 Aug; 19(4):357-60.
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  144. Hogan JW, Laird NM. Increasing efficiency from censored survival data by using random effects to model longitudinal covariates. Stat Methods Med Res. 1998 Mar; 7(1):28-48.
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  145. Kleinman KP, Ibrahim JG, Laird NM. A Bayesian framework for intent-to-treat analysis with missing data. Biometrics. 1998 Mar; 54(1):265-78.
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  146. Lipsitz SR, Dear KB, Laird NM, Molenberghs G. Tests for homogeneity of the risk difference when data are sparse. Biometrics. 1998 Mar; 54(1):148-60.
    View in: PubMed
  147. Cnaan A, Laird NM, Slasor P. Using the general linear mixed model to analyse unbalanced repeated measures and longitudinal data. Stat Med. 1997 Oct 30; 16(20):2349-80.
    View in: PubMed
  148. Fitzmaurice GM, Laird NM. Regression models for mixed discrete and continuous responses with potentially missing values. Biometrics. 1997 Mar; 53(1):110-22.
    View in: PubMed
  149. Van Eerdewegh P, Santangelo SL, Lee H, Laird NM, Blacker D. Probabilistic diagnosis in linkage analysis of bipolar disorder: putting weights on the fringe. Genet Epidemiol. 1997; 14(6):693-8.
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  150. Bates DW, Spell N, Cullen DJ, Burdick E, Laird N, Petersen LA, Small SD, Sweitzer BJ, Leape LL. The costs of adverse drug events in hospitalized patients. Adverse Drug Events Prevention Study Group. JAMA. 1997 Jan 22-29; 277(4):307-11.
    View in: PubMed
  151. Hogan JW, Laird NM. Mixture models for the joint distribution of repeated measures and event times. Stat Med. 1997 Jan 15-Feb 15; 16(1-3):239-57.
    View in: PubMed
  152. Hogan JW, Laird NM. Model-based approaches to analysing incomplete longitudinal and failure time data. Stat Med. 1997 Jan 15-Feb 15; 16(1-3):259-72.
    View in: PubMed
  153. Hogan JW, Laird NM. Intention-to-treat analyses for incomplete repeated measures data. Biometrics. 1996 Sep; 52(3):1002-17.
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  154. Fitzmaurice GM, Laird NM, Zahner GE, Daskalakis C. Bivariate logistic regression analysis of childhood psychopathology ratings using multiple informants. Am J Epidemiol. 1995 Dec 1; 142(11):1194-203.
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  155. Bates DW, Cullen DJ, Laird N, Petersen LA, Small SD, Servi D, Laffel G, Sweitzer BJ, Shea BF, Hallisey R, et al. Incidence of adverse drug events and potential adverse drug events. Implications for prevention. ADE Prevention Study Group. JAMA. 1995 Jul 5; 274(1):29-34.
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  156. Leape LL, Bates DW, Cullen DJ, Cooper J, Demonaco HJ, Gallivan T, Hallisey R, Ives J, Laird N, Laffel G, et al. Systems analysis of adverse drug events. ADE Prevention Study Group. JAMA. 1995 Jul 5; 274(1):35-43.
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  157. Xu X, Laird N, Dockery DW, Schouten JP, Rijcken B, Weiss ST. Age, period, and cohort effects on pulmonary function in a 24-year longitudinal study. Am J Epidemiol. 1995 Mar 15; 141(6):554-66.
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  158. Wang-Clow F, Lange M, Laird NM, Ware JH. A simulation study of estimators for rates of change in longitudinal studies with attrition. Stat Med. 1995 Feb 15; 14(3):283-97.
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  159. Fitzmaurice GM, Laird NM, Lipsitz SR. Analysing incomplete longitudinal binary responses: a likelihood-based approach. Biometrics. 1994 Sep; 50(3):601-12.
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  160. Stern RS, Laird N. The carcinogenic risk of treatments for severe psoriasis. Photochemotherapy Follow-up Study. Cancer. 1994 Jun 1; 73(11):2759-64.
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  161. Lipsitz SR, Fitzmaurice GM, Orav EJ, Laird NM. Performance of generalized estimating equations in practical situations. Biometrics. 1994 Mar; 50(1):270-8.
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  162. Lipsitz SR, Laird NM, Harrington DP. Weighted least squares analysis of repeated categorical measurements with outcomes subject to nonresponse. Biometrics. 1994 Mar; 50(1):11-24.
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  163. Laird NM, Skinner J, Kenward M. An analysis of two-period crossover designs with carry-over effects. Stat Med. 1992 Oct-Nov; 11(14-15):1967-79.
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  164. Laird NM, Donnelly C, Ware JH. Longitudinal studies with continuous responses. Stat Methods Med Res. 1992; 1(3):225-47.
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  165. Lawthers AG, Localio AR, Laird NM, Lipsitz S, Hebert L, Brennan TA. Physicians' perceptions of the risk of being sued. J Health Polit Policy Law. 1992; 17(3):463-82.
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  166. Berkey CS, Laird NM, Valadian I, Gardner J. Modelling adolescent blood pressure patterns and their prediction of adult pressures. Biometrics. 1991 Sep; 47(3):1005-18.
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  167. Localio AR, Lawthers AG, Brennan TA, Laird NM, Hebert LE, Peterson LM, Newhouse JP, Weiler PC, Hiatt HH. Relation between malpractice claims and adverse events due to negligence. Results of the Harvard Medical Practice Study III. N Engl J Med. 1991 Jul 25; 325(4):245-51.
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  168. Berkey CS, Laird NM, Gardner J, Valadian I. Longitudinal analysis of incomplete adolescent data. Ann Hum Biol. 1991 Jul-Aug; 18(4):311-26.
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  169. Brennan TA, Hebert LE, Laird NM, Lawthers A, Thorpe KE, Leape LL, Localio AR, Lipsitz SR, Newhouse JP, Weiler PC, et al. Hospital characteristics associated with adverse events and substandard care. JAMA. 1991 Jun 26; 265(24):3265-9.
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  170. Brennan TA, Leape LL, Laird NM, Hebert L, Localio AR, Lawthers AG, Newhouse JP, Weiler PC, Hiatt HH. Incidence of adverse events and negligence in hospitalized patients. Results of the Harvard Medical Practice Study I. N Engl J Med. 1991 Feb 7; 324(6):370-6.
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  171. Leape LL, Brennan TA, Laird N, Lawthers AG, Localio AR, Barnes BA, Hebert L, Newhouse JP, Weiler PC, Hiatt H. The nature of adverse events in hospitalized patients. Results of the Harvard Medical Practice Study II. N Engl J Med. 1991 Feb 7; 324(6):377-84.
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  172. Laird NM, Wang F. Estimating rates of change in randomized clinical trials. Control Clin Trials. 1990 Dec; 11(6):405-19.
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  173. Lipsitz SR, Laird NM, Harrington DP. Maximum likelihood regression methods for paired binary data. Stat Med. 1990 Dec; 9(12):1517-25.
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  174. Brennan TA, Localio AR, Leape LL, Laird NM, Peterson L, Hiatt HH, Barnes BA. Identification of adverse events occurring during hospitalization. A cross-sectional study of litigation, quality assurance, and medical records at two teaching hospitals. Ann Intern Med. 1990 Feb 1; 112(3):221-6.
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  175. Brennan TA, Leape LL, Laird NM, Localio AR, Hiatt HH. Incidence of adverse events and negligent care in hospitalized patients. Trans Assoc Am Physicians. 1990; 103:137-44.
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  176. Laird NM, Mosteller F. Some statistical methods for combining experimental results. Int J Technol Assess Health Care. 1990; 6(1):5-30.
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  177. Hine LK, Laird NM, Hewitt P, Chalmers TC. Meta-analysis of empirical long-term antiarrhythmic therapy after myocardial infarction. JAMA. 1989 Dec 1; 262(21):3037-40.
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  178. Hine LK, Laird N, Hewitt P, Chalmers TC. Meta-analytic evidence against prophylactic use of lidocaine in acute myocardial infarction. Arch Intern Med. 1989 Dec; 149(12):2694-8.
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  179. Hiatt HH, Barnes BA, Brennan TA, Laird NM, Lawthers AG, Leape LL, Localio AR, Newhouse JP, Peterson LM, Thorpe KE, et al. A study of medical injury and medical malpractice. N Engl J Med. 1989 Aug 17; 321(7):480-4.
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  180. Berlin JA, Laird NM, Sacks HS, Chalmers TC. A comparison of statistical methods for combining event rates from clinical trials. Stat Med. 1989 Feb; 8(2):141-51.
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  181. Laird NM. Missing data in longitudinal studies. Stat Med. 1988 Jan-Feb; 7(1-2):305-15.
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  182. Knuiman MW, Laird NM, Louis TA. Inter-laboratory variability in Ames assay results. Mutat Res. 1987 Oct; 180(2):171-82.
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  183. Laird NM. Thyroid cancer risk from exposure to ionizing radiation: a case study in the comparative potency model. Risk Anal. 1987 Sep; 7(3):299-309.
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  184. Wilson WR, Moss J, Joseph M, Laird N, Glinsiki M. Efficacy of an H1 antagonist, astemizole, for chronic allergic rhinitis. Am J Otolaryngol. 1987 May-Jun; 8(3):157-60.
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  185. DerSimonian R, Laird N. Meta-analysis in clinical trials. Control Clin Trials. 1986 Sep; 7(3):177-88.
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  186. Eavey RD, Nadol JB, Holmes LB, Laird NM, Lapey A, Joseph MP, Strome M. Kartagener's syndrome. A blinded, controlled study of cilia ultrastructure. Arch Otolaryngol Head Neck Surg. 1986 Jun; 112(6):646-50.
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  187. Berkey CS, Laird NM. Nonlinear growth curve analysis: estimating the population parameters. Ann Hum Biol. 1986 Mar-Apr; 13(2):111-28.
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  188. Glynn RJ, Bouchard GR, LoCastro JS, Laird NM. Aging and generational effects on drinking behaviors in men: results from the normative aging study. Am J Public Health. 1985 Dec; 75(12):1413-9.
    View in: PubMed
  189. Thurston GD, Laird NM. Tracing aerosol pollution. Science. 1985 Mar 22; 227(4693):1406-7.
    View in: PubMed
  190. Stiratelli R, Laird N, Ware JH. Random-effects models for serial observations with binary response. Biometrics. 1984 Dec; 40(4):961-71.
    View in: PubMed
  191. Heimendinger J, Laird N, Austin JE, Timmer P, Gershoff S. The effects of the WIC program on the growth of infants. Am J Clin Nutr. 1984 Dec; 40(6):1250-7.
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  192. Stern RS, Laird N, Melski J, Parrish JA, Fitzpatrick TB, Bleich HL. Cutaneous squamous-cell carcinoma in patients treated with PUVA. N Engl J Med. 1984 May 3; 310(18):1156-61.
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  193. Santiago GC, Rao TK, Laird NM. Effect of dialysis therapy on the hematopoietic system: the National Cooperative Dialysis Study. Kidney Int Suppl. 1983 Apr; (13):S95-100.
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  194. Rao TK, Roxe DM, Laird NM, Santiago GC. Hemodynamic and cardiac correlates of different hemodialysis regimes: the National Cooperative Dialysis Study. Kidney Int Suppl. 1983 Apr; (13):S89-94.
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  195. Schoenfeld PY, Henry RR, Laird NM, Roxe DM. Assessment of nutritional status of the National Cooperative Dialysis Study population. Kidney Int Suppl. 1983 Apr; (13):S80-8.
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  196. Parker TF, Laird NM, Lowrie EG. Comparison of the study groups in the National Cooperative Dialysis Study and a description of morbidity, mortality, and patient withdrawal. Kidney Int Suppl. 1983 Apr; (13):S42-9.
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  197. Harter HR, Laird NM, Teehan BP. Effects of dialysis prescription on bone and mineral metabolism: the National Cooperative Dialysis Study. Kidney Int Suppl. 1983 Apr; (13):S73-9.
    View in: PubMed
  198. Lowrie EG, Laird NM, Henry RR. Protocol for the National Cooperative Dialysis Study. Kidney Int Suppl. 1983 Apr; (13):S11-8.
    View in: PubMed
  199. Teehan BP, Laird NM, Harter HR. Influences of dialysis prescription on electrolyte and acid-base metabolism: the National Cooperative Dialysis Study. Kidney Int Suppl. 1983 Apr; (13):S66-72.
    View in: PubMed
  200. Laird NM, Berkey CS, Lowrie EG. Modeling success or failure of dialysis therapy: the National Cooperative Dialysis Study. Kidney Int Suppl. 1983 Apr; (13):S101-6.
    View in: PubMed
  201. Laird NM, Ware JH. Random-effects models for longitudinal data. Biometrics. 1982 Dec; 38(4):963-74.
    View in: PubMed
  202. Lowrie EG, Laird NM, Parker TF, Sargent JA. Effect of the hemodialysis prescription of patient morbidity: report from the National Cooperative Dialysis Study. N Engl J Med. 1981 Nov 12; 305(20):1176-81.
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  203. Laird NM, Weinstein MC, Stason WB. Sample-size estimation: a sensitivity analysis in the context of a clinical trial for treatment of mild hypertension. Am J Epidemiol. 1979 Apr; 109(4):408-19.
    View in: PubMed
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