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Jean Claire Lee, PH.D.

TitleAssociate Professor of Medicine
InstitutionBrigham and Women's Hospital
DepartmentMedicine
AddressChanning Laboratory
181 Longwood Ave
Boston MA 02115
Phone617/525-2652
Fax617/731-1541

 Bibliographic 
 selected publications
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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  1. Schaffer AC, Lee JC. Staphylococcal vaccines and immunotherapies. Infect Dis Clin North Am. 2009 Mar; 23(1):153-71.
    View in: PubMed
  2. Park S, Rich J, Hanses F, Lee JC. Defects in innate immunity predispose C57BL/6J-Leprdb/Leprdb mice to infection by Staphylococcus aureus. Infect Immun. 2009 Mar; 77(3):1008-14.
    View in: PubMed
  3. Tuchscherr LP, Buzzola FR, Alvarez LP, Lee JC, Sordelli DO. Antibodies to capsular polysaccharide and clumping factor A prevent mastitis and the emergence of unencapsulated and small-colony variants of Staphylococcus aureus in mice. Infect Immun. 2008 Dec; 76(12):5738-44.
    View in: PubMed
  4. Schaffer AC, Lee JC. Vaccination and passive immunisation against Staphylococcus aureus. Int J Antimicrob Agents. 2008 Nov; 32 Suppl 1:S71-8.
    View in: PubMed
  5. Ding Y, Onodera Y, Lee JC, Hooper DC. NorB, an efflux pump in Staphylococcus aureus strain MW2, contributes to bacterial fitness in abscesses. J Bacteriol. 2008 Nov; 190(21):7123-9.
    View in: PubMed
  6. Montgomery CP, Boyle-Vavra S, Adem PV, Lee JC, Husain AN, Clasen J, Daum RS. Comparison of virulence in community-associated methicillin-resistant Staphylococcus aureus pulsotypes USA300 and USA400 in a rat model of pneumonia. J Infect Dis. 2008 Aug 15; 198(4):561-70.
    View in: PubMed
  7. Kalka-Moll WM, Lee JC, Fabri M, Seifert H. Intrafamilial outbreak of subcutaneous abscesses caused by PVL-positive methicillin-sensitive Staphylococcus aureus. J Infect. 2008 Sep; 57(3):278-80.
    View in: PubMed
  8. McLoughlin RM, Lee JC, Kasper DL, Tzianabos AO. IFN-gamma regulated chemokine production determines the outcome of Staphylococcus aureus infection. J Immunol. 2008 Jul 15; 181(2):1323-32.
    View in: PubMed
  9. Flahaut S, Vinogradov E, Kelley KA, Brennan S, Hiramatsu K, Lee JC. Structural and biological characterization of a capsular polysaccharide produced by Staphylococcus haemolyticus. J Bacteriol. 2008 Mar; 190(5):1649-57.
    View in: PubMed
  10. Risley AL, Loughman A, Cywes-Bentley C, Foster TJ, Lee JC. Capsular polysaccharide masks clumping factor A-mediated adherence of Staphylococcus aureus to fibrinogen and platelets. J Infect Dis. 2007 Sep 15; 196(6):919-27.
    View in: PubMed
  11. McLoughlin RM, Solinga RM, Rich J, Zaleski KJ, Cocchiaro JL, Risley A, Tzianabos AO, Lee JC. CD4+ T cells and CXC chemokines modulate the pathogenesis of Staphylococcus aureus wound infections. Proc Natl Acad Sci U S A. 2006 Jul 5; 103(27):10408-13.
    View in: PubMed
  12. Schaffer AC, Solinga RM, Cocchiaro J, Portoles M, Kiser KB, Risley A, Randall SM, Valtulina V, Speziale P, Walsh E, Foster T, Lee JC. Immunization with Staphylococcus aureus clumping factor B, a major determinant in nasal carriage, reduces nasal colonization in a murine model. Infect Immun. 2006 Apr; 74(4):2145-53.
    View in: PubMed
  13. Cocchiaro JL, Gomez MI, Risley A, Solinga R, Sordelli DO, Lee JC. Molecular characterization of the capsule locus from non-typeable Staphylococcus aureus. Mol Microbiol. 2006 Feb; 59(3):948-60.
    View in: PubMed
  14. Tuchscherr LP, Buzzola FR, Alvarez LP, Caccuri RL, Lee JC, Sordelli DO. Capsule-negative Staphylococcus aureus induces chronic experimental mastitis in mice. Infect Immun. 2005 Dec; 73(12):7932-7.
    View in: PubMed
  15. Takeuchi F, Watanabe S, Baba T, Yuzawa H, Ito T, Morimoto Y, Kuroda M, Cui L, Takahashi M, Ankai A, Baba S, Fukui S, Lee JC, Hiramatsu K. Whole-genome sequencing of staphylococcus haemolyticus uncovers the extreme plasticity of its genome and the evolution of human-colonizing staphylococcal species. J Bacteriol. 2005 Nov; 187(21):7292-308.
    View in: PubMed
  16. Rich J, Lee JC. The pathogenesis of Staphylococcus aureus infection in the diabetic NOD mouse. Diabetes. 2005 Oct; 54(10):2904-10.
    View in: PubMed
  17. Watts A, Ke D, Wang Q, Pillay A, Nicholson-Weller A, Lee JC. Staphylococcus aureus strains that express serotype 5 or serotype 8 capsular polysaccharides differ in virulence. Infect Immun. 2005 Jun; 73(6):3502-11.
    View in: PubMed
  18. O'Riordan K, Lee JC. Staphylococcus aureus capsular polysaccharides. Clin Microbiol Rev. 2004 Jan; 17(1):218-34.
    View in: PubMed
  19. Kneidinger B, O'Riordan K, Li J, Brisson JR, Lee JC, Lam JS. Three highly conserved proteins catalyze the conversion of UDP-N-acetyl-D-glucosamine to precursors for the biosynthesis of O antigen in Pseudomonas aeruginosa O11 and capsule in Staphylococcus aureus type 5. Implications for the UDP-N-acetyl-L-fucosamine biosynthetic pathway. J Biol Chem. 2003 Feb 7; 278(6):3615-27.
    View in: PubMed
  20. Luong T, Sau S, Gomez M, Lee JC, Lee CY. Regulation of Staphylococcus aureus capsular polysaccharide expression by agr and sarA. Infect Immun. 2002 Feb; 70(2):444-50.
    View in: PubMed
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