Contact, publication, and social network information about Harvard faculty and fellows. Harvard Catalyst Profiles
Keywords
Last Name
Institution

Stephen Beaven Calderwood, M.D.

TitleMorton N. Swartz, M.D. Academy Professor of Medicine (Microbiology and Molecular Genetics)
InstitutionMassachusetts General Hospital
DepartmentMedicine
AddressMassachusetts General Hospital
Infectious Disease
55 Fruit St
Boston MA 02114
Phone617/726-3811
Fax617/726-7416

 Mentoring 
 completed student projects
A Study of Host and Pathogen Characteristics Mediating Human Immunity to V. cholerae
Summer, 06/16/08 - 08/15/08

 Bibliographic 
 selected publications
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
List All   |   Timeline
  1. Seed KD, Lazinski DW, Calderwood SB, Camilli A. A bacteriophage encodes its own CRISPR/Cas adaptive response to evade host innate immunity. Nature. 2013 Feb 28; 494(7438):489-91.
    View in: PubMed
  2. Alam MM, Arifuzzaman M, Ahmad SM, Hosen MI, Rahman MA, Rashu R, Sheikh A, Ryan ET, Calderwood SB, Qadri F. Study of Avidity of Antigen-Specific Antibody as a Means of Understanding Development of Long-Term Immunological Memory after Vibrio cholerae O1 Infection. Clin Vaccine Immunol. 2013 Jan; 20(1):17-23.
    View in: PubMed
  3. Johnson RA, Uddin T, Aktar A, Mohasin M, Alam MM, Chowdhury F, Harris JB, Larocque RC, Kelly Bufano M, Yu Y, Wu-Freeman Y, Leung DT, Sarracino D, Krastins B, Charles RC, Xu P, Kovác P, Calderwood SB, Qadri F, Ryan ET. Comparison of Immune Responses to the O-Specific Polysaccharide and Lipopolysaccharide of Vibrio cholerae O1 in Bangladeshi Adult Patients with Cholera. Clin Vaccine Immunol. 2012 Nov; 19(11):1712-21.
    View in: PubMed
  4. Seed KD, Faruque SM, Mekalanos JJ, Calderwood SB, Qadri F, Camilli A. Phase variable O antigen biosynthetic genes control expression of the major protective antigen and bacteriophage receptor in Vibrio cholerae O1. PLoS Pathog. 2012 Sep; 8(9):e1002917.
    View in: PubMed
  5. Sealfon R, Gire S, Ellis C, Calderwood S, Qadri F, Hensley L, Kellis M, Ryan ET, Larocque RC, Harris JB, Sabeti PC. High depth, whole-genome sequencing of cholera isolates from Haiti and the Dominican Republic. BMC Genomics. 2012; 13:468.
    View in: PubMed
  6. Weil AA, Chowdhury F, Khan AI, Leung DT, Uddin T, Begum YA, Saha NC, Charles RC, Larocque RC, Harris JB, Ryan ET, Qadri F, Calderwood SB. Frequency of Reexposure to Vibrio cholerae O1 Evaluated by Subsequent Vibriocidal Titer Rise after an Episode of Severe Cholera in a Highly Endemic Area in Bangladesh. Am J Trop Med Hyg. 2012 Nov; 87(5):921-6.
    View in: PubMed
  7. Kudva IT, Davis MA, Griffin RW, Garren J, Murray M, John M, Hovde CJ, Calderwood SB. Polymorphic Amplified Typing Sequences and Pulsed-Field Gel Electrophoresis Yield Comparable Results in the Strain Typing of a Diverse Set of Bovine Escherichia coli O157:H7 Isolates. Int J Microbiol. 2012; 2012:140105.
    View in: PubMed
  8. Harris JB, LaRocque RC, Qadri F, Ryan ET, Calderwood SB. Cholera. Lancet. 2012 Jun 30; 379(9835):2466-76.
    View in: PubMed
  9. Arifuzzaman M, Rashu R, Leung DT, Hosen MI, Bhuiyan TR, Bhuiyan MS, Rahman MA, Khanam F, Saha A, Charles RC, LaRocque RC, Weil AA, Clements JD, Holmes RK, Calderwood SB, Harris JB, Ryan ET, Qadri F. Antigen-specific memory T cell responses after vaccination with an oral killed cholera vaccine in Bangladeshi children and comparison to responses in patients with naturally acquired cholera. Clin Vaccine Immunol. 2012 Aug; 19(8):1304-11.
    View in: PubMed
  10. Kudva IT, Griffin RW, Krastins B, Sarracino DA, Calderwood SB, John M. Proteins other than the locus of enterocyte effacement-encoded proteins contribute to Escherichia coli O157:H7 adherence to bovine rectoanal junction stratified squamous epithelial cells. BMC Microbiol. 2012; 12:103.
    View in: PubMed
  11. Patel SM, Rahman MA, Mohasin M, Riyadh MA, Leung DT, Alam MM, Chowdhury F, Khan AI, Weil AA, Aktar A, Nazim M, LaRocque RC, Ryan ET, Calderwood SB, Qadri F, Harris JB. Memory B cell responses to Vibrio cholerae O1 lipopolysaccharide are associated with protection against infection from household contacts of patients with cholera in Bangladesh. Clin Vaccine Immunol. 2012 Jun; 19(6):842-8.
    View in: PubMed
  12. Leung DT, Chowdhury F, Calderwood SB, Qadri F, Ryan ET. Immune responses to cholera in children. Expert Rev Anti Infect Ther. 2012 Apr; 10(4):435-44.
    View in: PubMed
  13. Leung DT, Rahman MA, Mohasin M, Patel SM, Aktar A, Khanam F, Uddin T, Riyadh MA, Saha A, Alam MM, Chowdhury F, Khan AI, Charles R, LaRocque R, Harris JB, Calderwood SB, Qadri F, Ryan ET. Memory B cell and other immune responses in children receiving two doses of an oral killed cholera vaccine compared to responses following natural cholera infection in Bangladesh. Clin Vaccine Immunol. 2012 May; 19(5):690-8.
    View in: PubMed
  14. Borad AJ, Allison GM, Wang D, Ahmed S, Karim MM, Kane AV, Moy J, Hibberd PL, Ajjampur SS, Kang G, Calderwood SB, Ryan ET, Naumova E, Khan WA, Ward HD. Systemic antibody responses to the immunodominant p23 antigen and p23 polymorphisms in children with cryptosporidiosis in Bangladesh. Am J Trop Med Hyg. 2012 Feb; 86(2):214-22.
    View in: PubMed
  15. Arifuzzaman M, Ahmed T, Rahman MA, Chowdhury F, Rashu R, Khan AI, LaRocque RC, Harris JB, Bhuiyan TR, Ryan ET, Calderwood SB, Qadri F. Individuals with Le(a+b-) blood group have increased susceptibility to symptomatic vibrio cholerae O1 infection. PLoS Negl Trop Dis. 2011 Dec; 5(12):e1413.
    View in: PubMed
  16. Sheikh A, Charles RC, Sharmeen N, Rollins SM, Harris JB, Bhuiyan MS, Arifuzzaman M, Khanam F, Bukka A, Kalsy A, Porwollik S, Leung DT, Brooks WA, LaRocque RC, Hohmann EL, Cravioto A, Logvinenko T, Calderwood SB, McClelland M, Graham JE, Qadri F, Ryan ET. In vivo expression of Salmonella enterica serotype Typhi genes in the blood of patients with typhoid fever in Bangladesh. PLoS Negl Trop Dis. 2011 Dec; 5(12):e1419.
    View in: PubMed
  17. Bishop AL, Tarique AA, Patimalla B, Calderwood SB, Qadri F, Camilli A. Immunization of mice with vibrio cholerae outer-membrane vesicles protects against hyperinfectious challenge and blocks transmission. J Infect Dis. 2012 Feb 1; 205(3):412-21.
    View in: PubMed
  18. Xu P, Alam MM, Kalsy A, Charles RC, Calderwood SB, Qadri F, Ryan ET, Kovác P. Simple, direct conjugation of bacterial O-SP-core antigens to proteins: development of cholera conjugate vaccines. Bioconjug Chem. 2011 Oct 19; 22(10):2179-85.
    View in: PubMed
  19. Shin OS, Uddin T, Citorik R, Wang JP, Della Pelle P, Kradin RL, Bingle CD, Bingle L, Camilli A, Bhuiyan TR, Shirin T, Ryan ET, Calderwood SB, Finberg RW, Qadri F, Larocque RC, Harris JB. LPLUNC1 modulates innate immune responses to Vibrio cholerae. J Infect Dis. 2011 Nov; 204(9):1349-57.
    View in: PubMed
  20. Allison GM, Rogers KA, Borad A, Ahmed S, Karim MM, Kane AV, Hibberd PL, Naumova EN, Calderwood SB, Ryan ET, Khan WA, Ward HD. Antibody responses to the immunodominant Cryptosporidium gp15 antigen and gp15 polymorphisms in a case-control study of cryptosporidiosis in children in Bangladesh. Am J Trop Med Hyg. 2011 Jul; 85(1):97-104.
    View in: PubMed
  21. Leung DT, Rahman MA, Mohasin M, Riyadh MA, Patel SM, Alam MM, Chowdhury F, Khan AI, Kalivoda EJ, Aktar A, Bhuiyan MS, LaRocque RC, Harris JB, Calderwood SB, Qadri F, Ryan ET. Comparison of memory B cell, antibody-secreting cell, and plasma antibody responses in young children, older children, and adults with infection caused by Vibrio cholerae O1 El Tor Ogawa in Bangladesh. Clin Vaccine Immunol. 2011 Aug; 18(8):1317-25.
    View in: PubMed
  22. Kuchta A, Rahman T, Sennott EL, Bhuyian TR, Uddin T, Rashu R, Chowdhury F, Kahn AI, Arifuzzaman M, Weil AA, Podolsky M, LaRocque RC, Ryan ET, Calderwood SB, Qadri F, Harris JB. Vibrio cholerae O1 infection induces proinflammatory CD4+ T-cell responses in blood and intestinal mucosa of infected humans. Clin Vaccine Immunol. 2011 Aug; 18(8):1371-7.
    View in: PubMed
  23. Sheikh A, Khanam F, Sayeed MA, Rahman T, Pacek M, Hu Y, Rollins A, Bhuiyan MS, Rollins S, Kalsy A, Arifuzzaman M, Leung DT, Sarracino DA, Krastins B, Charles RC, Larocque RC, Cravioto A, Calderwood SB, Brooks WA, Harris JB, Labaer J, Qadri F, Ryan ET. Interferon-? and proliferation responses to Salmonella enterica Serotype Typhi proteins in patients with S. Typhi Bacteremia in Dhaka, Bangladesh. PLoS Negl Trop Dis. 2011 Jun; 5(6):e1193.
    View in: PubMed
  24. Farmer P, Almazor CP, Bahnsen ET, Barry D, Bazile J, Bloom BR, Bose N, Brewer T, Calderwood SB, Clemens JD, Cravioto A, Eustache E, Jérôme G, Gupta N, Harris JB, Hiatt HH, Holstein C, Hotez PJ, Ivers LC, Kerry VB, Koenig SP, Larocque RC, Léandre F, Lambert W, Lyon E, Mekalanos JJ, Mukherjee JS, Oswald C, Pape JW, Gretchko Prosper A, Rabinovich R, Raymonville M, Réjouit JR, Ronan LJ, Rosenberg ML, Ryan ET, Sachs JD, Sack DA, Surena C, Suri AA, Ternier R, Waldor MK, Walton D, Weigel JL. Meeting cholera's challenge to Haiti and the world: a joint statement on cholera prevention and care. PLoS Negl Trop Dis. 2011; 5(5):e1145.
    View in: PubMed
  25. Hira KG, Mackay MR, Hempstead AD, Ahmed S, Karim MM, O'Connor RM, Hibberd PL, Calderwood SB, Ryan ET, Khan WA, Ward HD. Genetic diversity of Cryptosporidium spp. from Bangladeshi children. J Clin Microbiol. 2011 Jun; 49(6):2307-10.
    View in: PubMed
  26. Alam MM, Riyadh MA, Fatema K, Rahman MA, Akhtar N, Ahmed T, Chowdhury MI, Chowdhury F, Calderwood SB, Harris JB, Ryan ET, Qadri F. Antigen-specific memory B-cell responses in Bangladeshi adults after one- or two-dose oral killed cholera vaccination and comparison with responses in patients with naturally acquired cholera. Clin Vaccine Immunol. 2011 May; 18(5):844-50.
    View in: PubMed
  27. Seed KD, Bodi KL, Kropinski AM, Ackermann HW, Calderwood SB, Qadri F, Camilli A. Evidence of a dominant lineage of Vibrio cholerae-specific lytic bacteriophages shed by cholera patients over a 10-year period in Dhaka, Bangladesh. MBio. 2011; 2(1):e00334-10.
    View in: PubMed
  28. Uddin T, Harris JB, Bhuiyan TR, Shirin T, Uddin MI, Khan AI, Chowdhury F, LaRocque RC, Alam NH, Ryan ET, Calderwood SB, Qadri F. Mucosal immunologic responses in cholera patients in Bangladesh. Clin Vaccine Immunol. 2011 Mar; 18(3):506-12.
    View in: PubMed
  29. Chin CS, Sorenson J, Harris JB, Robins WP, Charles RC, Jean-Charles RR, Bullard J, Webster DR, Kasarskis A, Peluso P, Paxinos EE, Yamaichi Y, Calderwood SB, Mekalanos JJ, Schadt EE, Waldor MK. The origin of the Haitian cholera outbreak strain. N Engl J Med. 2011 Jan 6; 364(1):33-42.
    View in: PubMed
  30. Sheikh A, Charles RC, Rollins SM, Harris JB, Bhuiyan MS, Khanam F, Bukka A, Kalsy A, Porwollik S, Brooks WA, LaRocque RC, Hohmann EL, Cravioto A, Logvinenko T, Calderwood SB, McClelland M, Graham JE, Qadri F, Ryan ET. Analysis of Salmonella enterica serotype paratyphi A gene expression in the blood of bacteremic patients in Bangladesh. PLoS Negl Trop Dis. 2010; 4(12):e908.
    View in: PubMed
  31. Kanjilal S, Citorik R, LaRocque RC, Ramoni MF, Calderwood SB. A systems biology approach to modeling vibrio cholerae gene expression under virulence-inducing conditions. J Bacteriol. 2010 Sep; 192(17):4300-10.
    View in: PubMed
  32. Kendall EA, Chowdhury F, Begum Y, Khan AI, Li S, Thierer JH, Bailey J, Kreisel K, Tacket CO, LaRocque RC, Harris JB, Ryan ET, Qadri F, Calderwood SB, Stine OC. Relatedness of Vibrio cholerae O1/O139 isolates from patients and their household contacts, determined by multilocus variable-number tandem-repeat analysis. J Bacteriol. 2010 Sep; 192(17):4367-76.
    View in: PubMed
  33. Charles RC, Sheikh A, Krastins B, Harris JB, Bhuiyan MS, LaRocque RC, Logvinenko T, Sarracino DA, Kudva IT, Eisenstein J, Podolsky MJ, Kalsy A, Brooks WA, Ludwig A, John M, Calderwood SB, Qadri F, Ryan ET. Characterization of anti-Salmonella enterica serotype Typhi antibody responses in bacteremic Bangladeshi patients by an immunoaffinity proteomics-based technology. Clin Vaccine Immunol. 2010 Aug; 17(8):1188-95.
    View in: PubMed
  34. Chowdhury F, Begum YA, Alam MM, Khan AI, Ahmed T, Bhuiyan MS, Harris JB, LaRocque RC, Faruque AS, Endtz H, Ryan ET, Cravioto A, Svennerholm AM, Calderwood SB, Qadri F. Concomitant enterotoxigenic Escherichia coli infection induces increased immune responses to Vibrio cholerae O1 antigens in patients with cholera in Bangladesh. Infect Immun. 2010 May; 78(5):2117-24.
    View in: PubMed
  35. Kamruzzaman M, Udden SM, Cameron DE, Calderwood SB, Nair GB, Mekalanos JJ, Faruque SM. Quorum-regulated biofilms enhance the development of conditionally viable, environmental Vibrio cholerae. Proc Natl Acad Sci U S A. 2010 Jan 26; 107(4):1588-93.
    View in: PubMed
  36. Khan AI, Chowdhury F, Harris JB, Larocque RC, Faruque AS, Ryan ET, Calderwood SB, Qadri F. Comparison of clinical features and immunological parameters of patients with dehydrating diarrhoea infected with Inaba or Ogawa serotypes of Vibrio cholerae O1. Scand J Infect Dis. 2010; 42(1):48-56.
    View in: PubMed
  37. Rahman KM, Duggal P, Harris JB, Saha SK, Streatfield PK, Ryan ET, Calderwood SB, Qadri F, Yunus M, LaRocque RC. Familial aggregation of Vibrio cholerae-associated infection in Matlab, Bangladesh. J Health Popul Nutr. 2009 Dec; 27(6):733-8.
    View in: PubMed
  38. Kim HB, Wang M, Ahmed S, Park CH, LaRocque RC, Faruque AS, Salam MA, Khan WA, Qadri F, Calderwood SB, Jacoby GA, Hooper DC. Transferable quinolone resistance in Vibrio cholerae. Antimicrob Agents Chemother. 2010 Feb; 54(2):799-803.
    View in: PubMed
  39. Weil AA, Khan AI, Chowdhury F, Larocque RC, Faruque AS, Ryan ET, Calderwood SB, Qadri F, Harris JB. Clinical outcomes in household contacts of patients with cholera in Bangladesh. Clin Infect Dis. 2009 Nov 15; 49(10):1473-9.
    View in: PubMed
  40. Kendall EA, Tarique AA, Hossain A, Alam MM, Arifuzzaman M, Akhtar N, Chowdhury F, Khan AI, Larocque RC, Harris JB, Ryan ET, Qadri F, Calderwood SB. Development of immunoglobulin M memory to both a T-cell-independent and a T-cell-dependent antigen following infection with Vibrio cholerae O1 in Bangladesh. Infect Immun. 2010 Jan; 78(1):253-9.
    View in: PubMed
  41. Nelson EJ, Harris JB, Morris JG, Calderwood SB, Camilli A. Cholera transmission: the host, pathogen and bacteriophage dynamic. Nat Rev Microbiol. 2009 Oct; 7(10):693-702.
    View in: PubMed
  42. Charles RC, Harris JB, Chase MR, Lebrun LM, Sheikh A, LaRocque RC, Logvinenko T, Rollins SM, Tarique A, Hohmann EL, Rosenberg I, Krastins B, Sarracino DA, Qadri F, Calderwood SB, Ryan ET. Comparative proteomic analysis of the PhoP regulon in Salmonella enterica serovar Typhi versus Typhimurium. PLoS One. 2009; 4(9):e6994.
    View in: PubMed
  43. Sheikh A, Bhuiyan MS, Khanam F, Chowdhury F, Saha A, Ahmed D, Jamil KM, LaRocque RC, Harris JB, Ahmad MM, Charles R, Brooks WA, Calderwood SB, Cravioto A, Ryan ET, Qadri F. Salmonella enterica serovar Typhi-specific immunoglobulin A antibody responses in plasma and antibody in lymphocyte supernatant specimens in Bangladeshi patients with suspected typhoid fever. Clin Vaccine Immunol. 2009 Nov; 16(11):1587-94.
    View in: PubMed
  44. Weil AA, Arifuzzaman M, Bhuiyan TR, LaRocque RC, Harris AM, Kendall EA, Hossain A, Tarique AA, Sheikh A, Chowdhury F, Khan AI, Murshed F, Parker KC, Banerjee KK, Ryan ET, Harris JB, Qadri F, Calderwood SB. Memory T-cell responses to Vibrio cholerae O1 infection. Infect Immun. 2009 Nov; 77(11):5090-6.
    View in: PubMed
  45. Rollenhagen JE, Kalsy A, Saksena R, Sheikh A, Alam MM, Qadri F, Calderwood SB, Kovác P, Ryan ET. Transcutaneous immunization with a synthetic hexasaccharide-protein conjugate induces anti-Vibrio cholerae lipopolysaccharide responses in mice. Vaccine. 2009 Aug 6; 27(36):4917-22.
    View in: PubMed
  46. Harris AM, Bhuiyan MS, Chowdhury F, Khan AI, Hossain A, Kendall EA, Rahman A, LaRocque RC, Wrammert J, Ryan ET, Qadri F, Calderwood SB, Harris JB. Antigen-specific memory B-cell responses to Vibrio cholerae O1 infection in Bangladesh. Infect Immun. 2009 Sep; 77(9):3850-6.
    View in: PubMed
  47. Nelson EJ, Tanudra A, Chowdhury A, Kane AV, Qadri F, Calderwood SB, Coburn J, Camilli A. High prevalence of spirochetosis in cholera patients, Bangladesh. Emerg Infect Dis. 2009 Apr; 15(4):571-3.
    View in: PubMed
  48. Harris JB, Podolsky MJ, Bhuiyan TR, Chowdhury F, Khan AI, Larocque RC, Logvinenko T, Kendall J, Faruque AS, Nagler CR, Ryan ET, Qadri F, Calderwood SB. Immunologic responses to Vibrio cholerae in patients co-infected with intestinal parasites in Bangladesh. PLoS Negl Trop Dis. 2009; 3(3):e403.
    View in: PubMed
  49. Means TK, Mylonakis E, Tampakakis E, Colvin RA, Seung E, Puckett L, Tai MF, Stewart CR, Pukkila-Worley R, Hickman SE, Moore KJ, Calderwood SB, Hacohen N, Luster AD, El Khoury J. Evolutionarily conserved recognition and innate immunity to fungal pathogens by the scavenger receptors SCARF1 and CD36. J Exp Med. 2009 Mar 16; 206(3):637-53.
    View in: PubMed
  50. Bhuiyan TR, Lundin SB, Khan AI, Lundgren A, Harris JB, Calderwood SB, Qadri F. Cholera caused by Vibrio cholerae O1 induces T-cell responses in the circulation. Infect Immun. 2009 May; 77(5):1888-93.
    View in: PubMed
  51. Larocque RC, Sabeti P, Duggal P, Chowdhury F, Khan AI, Lebrun LM, Harris JB, Ryan ET, Qadri F, Calderwood SB. A variant in long palate, lung and nasal epithelium clone 1 is associated with cholera in a Bangladeshi population. Genes Immun. 2009 Apr; 10(3):267-72.
    View in: PubMed
  52. Harris AM, Chowdhury F, Begum YA, Khan AI, Faruque AS, Svennerholm AM, Harris JB, Ryan ET, Cravioto A, Calderwood SB, Qadri F. Shifting prevalence of major diarrheal pathogens in patients seeking hospital care during floods in 1998, 2004, and 2007 in Dhaka, Bangladesh. Am J Trop Med Hyg. 2008 Nov; 79(5):708-14.
    View in: PubMed
  53. Chowdhury F, Khan AI, Harris JB, LaRocque RC, Chowdhury MI, Ryan ET, Faruque AS, Calderwood SB, Qadri F. A comparison of clinical and immunologic features in children and older patients hospitalized with severe cholera in Bangladesh. Pediatr Infect Dis J. 2008 Nov; 27(11):986-92.
    View in: PubMed
  54. Nelson EJ, Chowdhury A, Flynn J, Schild S, Bourassa L, Shao Y, LaRocque RC, Calderwood SB, Qadri F, Camilli A. Transmission of Vibrio cholerae is antagonized by lytic phage and entry into the aquatic environment. PLoS Pathog. 2008 Oct; 4(10):e1000187.
    View in: PubMed
  55. Jayasekera CR, Harris JB, Bhuiyan S, Chowdhury F, Khan AI, Faruque AS, Larocque RC, Ryan ET, Ahmed R, Qadri F, Calderwood SB. Cholera toxin-specific memory B cell responses are induced in patients with dehydrating diarrhea caused by Vibrio cholerae O1. J Infect Dis. 2008 Oct 1; 198(7):1055-61.
    View in: PubMed
  56. Zahid MS, Udden SM, Faruque AS, Calderwood SB, Mekalanos JJ, Faruque SM. Effect of phage on the infectivity of Vibrio cholerae and emergence of genetic variants. Infect Immun. 2008 Nov; 76(11):5266-73.
    View in: PubMed
  57. Kudva IT, Calderwood SB, John M. Proteomics-based expression library screening - a platform technology for rapid discovery of pathogen-specific markers of infection. Expert Opin Med Diagn. 2008 Aug; 2(8):979-89.
    View in: PubMed
  58. LaRocque RC, Krastins B, Harris JB, Lebrun LM, Parker KC, Chase M, Ryan ET, Qadri F, Sarracino D, Calderwood SB. Proteomic analysis of Vibrio cholerae in human stool. Infect Immun. 2008 Sep; 76(9):4145-51.
    View in: PubMed
  59. Harris JB, LaRocque RC, Chowdhury F, Khan AI, Logvinenko T, Faruque AS, Ryan ET, Qadri F, Calderwood SB. Susceptibility to Vibrio cholerae infection in a cohort of household contacts of patients with cholera in Bangladesh. PLoS Negl Trop Dis. 2008; 2(4):e221.
    View in: PubMed
  60. Rollins SM, Peppercorn A, Young JS, Drysdale M, Baresch A, Bikowski MV, Ashford DA, Quinn CP, Handfield M, Hillman JD, Lyons CR, Koehler TM, Calderwood SB, Ryan ET. Application of in vivo induced antigen technology (IVIAT) to Bacillus anthracis. PLoS One. 2008; 3(3):e1824.
    View in: PubMed
  61. Nelson EJ, Chowdhury A, Harris JB, Begum YA, Chowdhury F, Khan AI, Larocque RC, Bishop AL, Ryan ET, Camilli A, Qadri F, Calderwood SB. Complexity of rice-water stool from patients with Vibrio cholerae plays a role in the transmission of infectious diarrhea. Proc Natl Acad Sci U S A. 2007 Nov 27; 104(48):19091-6.
    View in: PubMed
  62. Schild S, Tamayo R, Nelson EJ, Qadri F, Calderwood SB, Camilli A. Genes induced late in infection increase fitness of Vibrio cholerae after release into the environment. Cell Host Microbe. 2007 Oct 11; 2(4):264-77.
    View in: PubMed
  63. Begun J, Gaiani JM, Rohde H, Mack D, Calderwood SB, Ausubel FM, Sifri CD. Staphylococcal biofilm exopolysaccharide protects against Caenorhabditis elegans immune defenses. PLoS Pathog. 2007 Apr; 3(4):e57.
    View in: PubMed
  64. Ghose C, Kalsy A, Sheikh A, Rollenhagen J, John M, Young J, Rollins SM, Qadri F, Calderwood SB, Kelly CP, Ryan ET. Transcutaneous immunization with Clostridium difficile toxoid A induces systemic and mucosal immune responses and toxin A-neutralizing antibodies in mice. Infect Immun. 2007 Jun; 75(6):2826-32.
    View in: PubMed
  65. Aperis G, Fuchs BB, Anderson CA, Warner JE, Calderwood SB, Mylonakis E. Galleria mellonella as a model host to study infection by the Francisella tularensis live vaccine strain. Microbes Infect. 2007 May; 9(6):729-34.
    View in: PubMed
  66. Rollenhagen JE, Kalsy A, Cerda F, John M, Harris JB, Larocque RC, Qadri F, Calderwood SB, Taylor RK, Ryan ET. Transcutaneous immunization with toxin-coregulated pilin A induces protective immunity against Vibrio cholerae O1 El Tor challenge in mice. Infect Immun. 2006 Oct; 74(10):5834-9.
    View in: PubMed
  67. Harris JB, Baresch-Bernal A, Rollins SM, Alam A, LaRocque RC, Bikowski M, Peppercorn AF, Handfield M, Hillman JD, Qadri F, Calderwood SB, Hohmann E, Breiman RF, Brooks WA, Ryan ET. Identification of in vivo-induced bacterial protein antigens during human infection with Salmonella enterica serovar Typhi. Infect Immun. 2006 Sep; 74(9):5161-8.
    View in: PubMed
  68. Ryan ET, Calderwood SB, Qadri F. Live attenuated oral cholera vaccines. Expert Rev Vaccines. 2006 Aug; 5(4):483-94.
    View in: PubMed
  69. LaRocque RC, Harris JB, Ryan ET, Qadri F, Calderwood SB. Postgenomic approaches to cholera vaccine development. Expert Rev Vaccines. 2006 Jun; 5(3):337-46.
    View in: PubMed
  70. Schwartz BS, Harris JB, Khan AI, Larocque RC, Sack DA, Malek MA, Faruque AS, Qadri F, Calderwood SB, Luby SP, Ryan ET. Diarrheal epidemics in Dhaka, Bangladesh, during three consecutive floods: 1988, 1998, and 2004. Am J Trop Med Hyg. 2006 Jun; 74(6):1067-73.
    View in: PubMed
  71. Kudva IT, Krastins B, Sheng H, Griffin RW, Sarracino DA, Tarr PI, Hovde CJ, Calderwood SB, John M. Proteomics-based expression library screening (PELS): a novel method for rapidly defining microbial immunoproteomes. Mol Cell Proteomics. 2006 Aug; 5(8):1514-9.
    View in: PubMed
  72. Butler SM, Nelson EJ, Chowdhury N, Faruque SM, Calderwood SB, Camilli A. Cholera stool bacteria repress chemotaxis to increase infectivity. Mol Microbiol. 2006 Apr; 60(2):417-26.
    View in: PubMed
  73. Sifri CD, Baresch-Bernal A, Calderwood SB, von Eiff C. Virulence of Staphylococcus aureus small colony variants in the Caenorhabditis elegans infection model. Infect Immun. 2006 Feb; 74(2):1091-6.
    View in: PubMed
  74. Tang RJ, Breger J, Idnurm A, Gerik KJ, Lodge JK, Heitman J, Calderwood SB, Mylonakis E. Cryptococcus neoformans gene involved in mammalian pathogenesis identified by a Caenorhabditis elegans progeny-based approach. Infect Immun. 2005 Dec; 73(12):8219-25.
    View in: PubMed
  75. Harris JB, Khan AI, LaRocque RC, Dorer DJ, Chowdhury F, Faruque AS, Sack DA, Ryan ET, Qadri F, Calderwood SB. Blood group, immunity, and risk of infection with Vibrio cholerae in an area of endemicity. Infect Immun. 2005 Nov; 73(11):7422-7.
    View in: PubMed
  76. Alam A, Larocque RC, Harris JB, Vanderspurt C, Ryan ET, Qadri F, Calderwood SB. Hyperinfectivity of human-passaged Vibrio cholerae can be modeled by growth in the infant mouse. Infect Immun. 2005 Oct; 73(10):6674-9.
    View in: PubMed
  77. Qadri F, Svennerholm AM, Shamsuzzaman S, Bhuiyan TR, Harris JB, Ghosh AN, Nair GB, Weintraub A, Faruque SM, Ryan ET, Sack DA, Calderwood SB. Reduction in capsular content and enhanced bacterial susceptibility to serum killing of Vibrio cholerae O139 associated with the 2002 cholera epidemic in Bangladesh. Infect Immun. 2005 Oct; 73(10):6577-83.
    View in: PubMed
  78. Kudva IT, Griffin RW, Garren JM, Calderwood SB, John M. Identification of a protein subset of the anthrax spore immunome in humans immunized with the anthrax vaccine adsorbed preparation. Infect Immun. 2005 Sep; 73(9):5685-96.
    View in: PubMed
  79. Larocque RC, Harris JB, Dziejman M, Li X, Khan AI, Faruque AS, Faruque SM, Nair GB, Ryan ET, Qadri F, Mekalanos JJ, Calderwood SB. Transcriptional profiling of Vibrio cholerae recovered directly from patient specimens during early and late stages of human infection. Infect Immun. 2005 Aug; 73(8):4488-93.
    View in: PubMed
  80. Mylonakis E, Moreno R, El Khoury JB, Idnurm A, Heitman J, Calderwood SB, Ausubel FM, Diener A. Galleria mellonella as a model system to study Cryptococcus neoformans pathogenesis. Infect Immun. 2005 Jul; 73(7):3842-50.
    View in: PubMed
  81. John M, Kudva IT, Griffin RW, Dodson AW, McManus B, Krastins B, Sarracino D, Progulske-Fox A, Hillman JD, Handfield M, Tarr PI, Calderwood SB. Use of in vivo-induced antigen technology for identification of Escherichia coli O157:H7 proteins expressed during human infection. Infect Immun. 2005 May; 73(5):2665-79.
    View in: PubMed
  82. Begun J, Sifri CD, Goldman S, Calderwood SB, Ausubel FM. Staphylococcus aureus virulence factors identified by using a high-throughput Caenorhabditis elegans-killing model. Infect Immun. 2005 Feb; 73(2):872-7.
    View in: PubMed
  83. Rollins SM, Peppercorn A, Hang L, Hillman JD, Calderwood SB, Handfield M, Ryan ET. In vivo induced antigen technology (IVIAT). Cell Microbiol. 2005 Jan; 7(1):1-9.
    View in: PubMed
  84. Khan WA, Rogers KA, Karim MM, Ahmed S, Hibberd PL, Calderwood SB, Ryan ET, Ward HD. Cryptosporidiosis among Bangladeshi children with diarrhea: a prospective, matched, case-control study of clinical features, epidemiology and systemic antibody responses. Am J Trop Med Hyg. 2004 Oct; 71(4):412-9.
    View in: PubMed
  85. Mylonakis E, Idnurm A, Moreno R, El Khoury J, Rottman JB, Ausubel FM, Heitman J, Calderwood SB. Cryptococcus neoformans Kin1 protein kinase homologue, identified through a Caenorhabditis elegans screen, promotes virulence in mammals. Mol Microbiol. 2004 Oct; 54(2):407-19.
    View in: PubMed
  86. Moy TI, Mylonakis E, Calderwood SB, Ausubel FM. Cytotoxicity of hydrogen peroxide produced by Enterococcus faecium. Infect Immun. 2004 Aug; 72(8):4512-20.
    View in: PubMed
  87. Asaduzzaman M, Ryan ET, John M, Hang L, Khan AI, Faruque AS, Taylor RK, Calderwood SB, Qadri F. The major subunit of the toxin-coregulated pilus TcpA induces mucosal and systemic immunoglobulin A immune responses in patients with cholera caused by Vibrio cholerae O1 and O139. Infect Immun. 2004 Aug; 72(8):4448-54.
    View in: PubMed
  88. Engelbert M, Mylonakis E, Ausubel FM, Calderwood SB, Gilmore MS. Contribution of gelatinase, serine protease, and fsr to the pathogenesis of Enterococcus faecalis endophthalmitis. Infect Immun. 2004 Jun; 72(6):3628-33.
    View in: PubMed
  89. Kudva IT, Griffin RW, Murray M, John M, Perna NT, Barrett TJ, Calderwood SB. Insertions, deletions, and single-nucleotide polymorphisms at rare restriction enzyme sites enhance discriminatory power of polymorphic amplified typing sequences, a novel strain typing system for Escherichia coli O157:H7. J Clin Microbiol. 2004 Jun; 42(6):2388-97.
    View in: PubMed
  90. Saha D, LaRocque RC, Khan AI, Harris JB, Begum YA, Akramuzzaman SM, Faruque AS, Ryan ET, Qadri F, Calderwood SB. Incomplete correlation of serum vibriocidal antibody titer with protection from Vibrio cholerae infection in urban Bangladesh. J Infect Dis. 2004 Jun 15; 189(12):2318-22.
    View in: PubMed
  91. Apidianakis Y, Rahme LG, Heitman J, Ausubel FM, Calderwood SB, Mylonakis E. Challenge of Drosophila melanogaster with Cryptococcus neoformans and role of the innate immune response. Eukaryot Cell. 2004 Apr; 3(2):413-9.
    View in: PubMed
  92. Qadri F, Ryan ET, Faruque AS, Ahmed F, Khan AI, Islam MM, Akramuzzaman SM, Sack DA, Calderwood SB. Antigen-specific immunoglobulin A antibodies secreted from circulating B cells are an effective marker for recent local immune responses in patients with cholera: comparison to antibody-secreting cell responses and other immunological markers. Infect Immun. 2003 Aug; 71(8):4808-14.
    View in: PubMed
  93. Hang L, John M, Asaduzzaman M, Bridges EA, Vanderspurt C, Kirn TJ, Taylor RK, Hillman JD, Progulske-Fox A, Handfield M, Ryan ET, Calderwood SB. Use of in vivo-induced antigen technology (IVIAT) to identify genes uniquely expressed during human infection with Vibrio cholerae. Proc Natl Acad Sci U S A. 2003 Jul 8; 100(14):8508-13.
    View in: PubMed
  94. Garsin DA, Villanueva JM, Begun J, Kim DH, Sifri CD, Calderwood SB, Ruvkun G, Ausubel FM. Long-lived C. elegans daf-2 mutants are resistant to bacterial pathogens. Science. 2003 Jun 20; 300(5627):1921.
    View in: PubMed
  95. Mylonakis E, Ausubel FM, Tang RJ, Calderwood SB. The art of serendipity: killing of Caenorhabditis elegans by human pathogens as a model of bacterial and fungal pathogenesis. Expert Rev Anti Infect Ther. 2003 Jun; 1(1):167-73.
    View in: PubMed
  96. Sifri CD, Begun J, Ausubel FM, Calderwood SB. Caenorhabditis elegans as a model host for Staphylococcus aureus pathogenesis. Infect Immun. 2003 Apr; 71(4):2208-17.
    View in: PubMed
  97. Bina J, Zhu J, Dziejman M, Faruque S, Calderwood S, Mekalanos J. ToxR regulon of Vibrio cholerae and its expression in vibrios shed by cholera patients. Proc Natl Acad Sci U S A. 2003 Mar 4; 100(5):2801-6.
    View in: PubMed
  98. Mylonakis E, Ausubel FM, Perfect JR, Heitman J, Calderwood SB. Killing of Caenorhabditis elegans by Cryptococcus neoformans as a model of yeast pathogenesis. Proc Natl Acad Sci U S A. 2002 Nov 26; 99(24):15675-80.
    View in: PubMed
  99. Sifri CD, Mylonakis E, Singh KV, Qin X, Garsin DA, Murray BE, Ausubel FM, Calderwood SB. Virulence effect of Enterococcus faecalis protease genes and the quorum-sensing locus fsr in Caenorhabditis elegans and mice. Infect Immun. 2002 Oct; 70(10):5647-50.
    View in: PubMed
  100. Mylonakis E, Engelbert M, Qin X, Sifri CD, Murray BE, Ausubel FM, Gilmore MS, Calderwood SB. The Enterococcus faecalis fsrB gene, a key component of the fsr quorum-sensing system, is associated with virulence in the rabbit endophthalmitis model. Infect Immun. 2002 Aug; 70(8):4678-81.
    View in: PubMed
  101. Mylonakis E, Paliou M, Hohmann EL, Calderwood SB, Wing EJ. Listeriosis during pregnancy: a case series and review of 222 cases. Medicine (Baltimore). 2002 Jul; 81(4):260-9.
    View in: PubMed
  102. John M, Bridges EA, Miller AO, Calderwood SB, Ryan ET. Comparison of mucosal and systemic humoral immune responses after transcutaneous and oral immunization strategies. Vaccine. 2002 Jun 21; 20(21-22):2720-6.
    View in: PubMed
  103. Merrell DS, Butler SM, Qadri F, Dolganov NA, Alam A, Cohen MB, Calderwood SB, Schoolnik GK, Camilli A. Host-induced epidemic spread of the cholera bacterium. Nature. 2002 Jun 6; 417(6889):642-5.
    View in: PubMed
  104. Kudva IT, Evans PS, Perna NT, Barrett TJ, DeCastro GJ, Ausubel FM, Blattner FR, Calderwood SB. Polymorphic amplified typing sequences provide a novel approach to Escherichia coli O157:H7 strain typing. J Clin Microbiol. 2002 Apr; 40(4):1152-9.
    View in: PubMed
  105. Kudva IT, Evans PS, Perna NT, Barrett TJ, Ausubel FM, Blattner FR, Calderwood SB. Strains of Escherichia coli O157:H7 differ primarily by insertions or deletions, not single-nucleotide polymorphisms. J Bacteriol. 2002 Apr; 184(7):1873-9.
    View in: PubMed
  106. Al-Kasim FA, Thornley I, Rolland M, Lau W, Tsang R, Freedman MH, Saunders EF, Calderwood S, Doyle JJ. Single-centre experience with allogeneic bone marrow transplantation for acute lymphoblastic leukaemia in childhood: similar survival after matched-related and matched-unrelated donor transplants. Br J Haematol. 2002 Feb; 116(2):483-90.
    View in: PubMed
  107. Choi JY, Sifri CD, Goumnerov BC, Rahme LG, Ausubel FM, Calderwood SB. Identification of virulence genes in a pathogenic strain of Pseudomonas aeruginosa by representational difference analysis. J Bacteriol. 2002 Feb; 184(4):952-61.
    View in: PubMed
  108. Mylonakis E, Calderwood SB. Infective endocarditis in adults. N Engl J Med. 2001 Nov 1; 345(18):1318-30.
    View in: PubMed
  109. Park SY, Kelminson KL, Lee AK, Zhang P, Warner RE, Rehkopf DH, Calderwood SB, Koehler JE. Identification, characterization, and functional analysis of a gene encoding the ferric uptake regulation protein in Bartonella species. J Bacteriol. 2001 Oct; 183(19):5751-5.
    View in: PubMed
  110. Garsin DA, Sifri CD, Mylonakis E, Qin X, Singh KV, Murray BE, Calderwood SB, Ausubel FM. A simple model host for identifying Gram-positive virulence factors. Proc Natl Acad Sci U S A. 2001 Sep 11; 98(19):10892-7.
    View in: PubMed
  111. Allen UD, Tellier R, Doyle J, Petric M, Wasfy S, Kumar P, Calderwood S, Freedman M, Saunders F. The utility of plasma polymerase chain reaction for human herpes virus-6 among pediatric bone marrow transplant recipients: results of a pilot study. Bone Marrow Transplant. 2001 Sep; 28(5):473-7.
    View in: PubMed
  112. Ryan ET, Bridges EA, Crean TI, Gausia K, Hamadani JD, Aziz A, Hawkes S, Begum M, Bogaerts J, Faruque SM, Salam MA, Fuchs GJ, Calderwood SB. Local production of anti-vibrio cholerae mucosal antibody in reproductive tract tissues after cholera. J Infect Dis. 2001 Sep 1; 184(5):643-7.
    View in: PubMed
  113. Ryan ET, Calderwood SB. Cholera vaccines. J Travel Med. 2001 Mar-Apr; 8(2):82-91.
    View in: PubMed
  114. Mylonakis E, Ryan ET, Calderwood SB. Clostridium difficile--Associated diarrhea: A review. Arch Intern Med. 2001 Feb 26; 161(4):525-33.
    View in: PubMed
  115. Behari J, Stagon L, Calderwood SB. pepA, a gene mediating pH regulation of virulence genes in Vibrio cholerae. J Bacteriol. 2001 Jan; 183(1):178-88.
    View in: PubMed
  116. Ryan ET, Calderwood SB. Cholera vaccines. Clin Infect Dis. 2000 Aug; 31(2):561-5.
    View in: PubMed
  117. Ryan ET, Dhar U, Khan WA, Salam MA, Faruque AS, Fuchs GJ, Calderwood SB, Bennish ML. Mortality, morbidity, and microbiology of endemic cholera among hospitalized patients in Dhaka, Bangladesh. Am J Trop Med Hyg. 2000 Jul-Aug; 63(1-2):12-20.
    View in: PubMed
  118. Murley YM, Behari J, Griffin R, Calderwood SB. Classical and El Tor biotypes of Vibrio cholerae differ in timing of transcription of tcpPH during growth in inducing conditions. Infect Immun. 2000 May; 68(5):3010-4.
    View in: PubMed
  119. Rogers MB, Sexton JA, DeCastro GJ, Calderwood SB. Identification of an operon required for ferrichrome iron utilization in Vibrio cholerae. J Bacteriol. 2000 Apr; 182(8):2350-3.
    View in: PubMed
  120. Singh IS, Viscardi RM, Kalvakolanu I, Calderwood S, Hasday JD. Inhibition of tumor necrosis factor-alpha transcription in macrophages exposed to febrile range temperature. A possible role for heat shock factor-1 as a negative transcriptional regulator. J Biol Chem. 2000 Mar 31; 275(13):9841-8.
    View in: PubMed
  121. Butterton JR, Choi MH, Watnick PI, Carroll PA, Calderwood SB. Vibrio cholerae VibF is required for vibriobactin synthesis and is a member of the family of nonribosomal peptide synthetases. J Bacteriol. 2000 Mar; 182(6):1731-8.
    View in: PubMed
  122. John M, Crean TI, Calderwood SB, Ryan ET. In vitro and in vivo analyses of constitutive and in vivo-induced promoters in attenuated vaccine and vector strains of Vibrio cholerae. Infect Immun. 2000 Mar; 68(3):1171-5.
    View in: PubMed
  123. Crean TI, John M, Calderwood SB, Ryan ET. Optimizing the germfree mouse model for in vivo evaluation of oral Vibrio cholerae vaccine and vector strains. Infect Immun. 2000 Feb; 68(2):977-81.
    View in: PubMed
  124. Ryan ET, Crean TI, Kochi SK, John M, Luciano AA, Killeen KP, Klose KE, Calderwood SB. Development of a DeltaglnA balanced lethal plasmid system for expression of heterologous antigens by attenuated vaccine vector strains of Vibrio cholerae. Infect Immun. 2000 Jan; 68(1):221-6.
    View in: PubMed
  125. Konadu E, Donohue-Rolfe A, Calderwood SB, Pozsgay V, Shiloach J, Robbins JB, Szu SC. Syntheses and immunologic properties of Escherichia coli O157 O-specific polysaccharide and Shiga toxin 1 B subunit conjugates in mice. Infect Immun. 1999 Nov; 67(11):6191-3.
    View in: PubMed
  126. Murley YM, Carroll PA, Skorupski K, Taylor RK, Calderwood SB. Differential transcription of the tcpPH operon confers biotype-specific control of the Vibrio cholerae ToxR virulence regulon. Infect Immun. 1999 Oct; 67(10):5117-23.
    View in: PubMed
  127. Ryan ET, Crean TI, John M, Butterton JR, Clements JD, Calderwood SB. In vivo expression and immunoadjuvancy of a mutant of heat-labile enterotoxin of Escherichia coli in vaccine and vector strains of Vibrio cholerae. Infect Immun. 1999 Apr; 67(4):1694-701.
    View in: PubMed
  128. Lin W, Fullner KJ, Clayton R, Sexton JA, Rogers MB, Calia KE, Calderwood SB, Fraser C, Mekalanos JJ. Identification of a vibrio cholerae RTX toxin gene cluster that is tightly linked to the cholera toxin prophage. Proc Natl Acad Sci U S A. 1999 Feb 2; 96(3):1071-6.
    View in: PubMed
  129. Wong SM, Carroll PA, Rahme LG, Ausubel FM, Calderwood SB. Modulation of expression of the ToxR regulon in Vibrio cholerae by a member of the two-component family of response regulators. Infect Immun. 1998 Dec; 66(12):5854-61.
    View in: PubMed
  130. Mylonakis E, Hohmann EL, Calderwood SB. Central nervous system infection with Listeria monocytogenes. 33 years' experience at a general hospital and review of 776 episodes from the literature. Medicine (Baltimore). 1998 Sep; 77(5):313-36.
    View in: PubMed
  131. John MD, Hibberd PL, Karchmer AW, Sleeper LA, Calderwood SB. Staphylococcus aureus prosthetic valve endocarditis: optimal management and risk factors for death. Clin Infect Dis. 1998 Jun; 26(6):1302-9.
    View in: PubMed
  132. Watnick PI, Butterton JR, Calderwood SB. The interaction of the Vibrio cholerae transcription factors, Fur and IrgB, with the overlapping promoters of two virulence genes, irgA and irgB. Gene. 1998 Mar 16; 209(1-2):65-70.
    View in: PubMed
  133. Calia KE, Waldor MK, Calderwood SB. Use of representational difference analysis to identify genomic differences between pathogenic strains of Vibrio cholerae. Infect Immun. 1998 Feb; 66(2):849-52.
    View in: PubMed
  134. Pegues DA, Colby C, Hibberd PL, Cohen LG, Ausubel FM, Calderwood SB, Hooper DC. The epidemiology of resistance to ofloxacin and oxacillin among clinical coagulase-negative staphylococcal isolates: analysis of risk factors and strain types. Clin Infect Dis. 1998 Jan; 26(1):72-9.
    View in: PubMed
  135. Rahme LG, Tan MW, Le L, Wong SM, Tompkins RG, Calderwood SB, Ausubel FM. Use of model plant hosts to identify Pseudomonas aeruginosa virulence factors. Proc Natl Acad Sci U S A. 1997 Nov 25; 94(24):13245-50.
    View in: PubMed
  136. Carroll PA, Tashima KT, Rogers MB, DiRita VJ, Calderwood SB. Phase variation in tcpH modulates expression of the ToxR regulon in Vibrio cholerae. Mol Microbiol. 1997 Sep; 25(6):1099-111.
    View in: PubMed
  137. Ryan ET, Butterton JR, Zhang T, Baker MA, Stanley SL, Calderwood SB. Oral immunization with attenuated vaccine strains of Vibrio cholerae expressing a dodecapeptide repeat of the serine-rich Entamoeba histolytica protein fused to the cholera toxin B subunit induces systemic and mucosal antiamebic and anti-V. cholerae antibody responses in mice. Infect Immun. 1997 Aug; 65(8):3118-25.
    View in: PubMed
  138. Ryan ET, Butterton JR, Smith RN, Carroll PA, Crean TI, Calderwood SB. Protective immunity against Clostridium difficile toxin A induced by oral immunization with a live, attenuated Vibrio cholerae vector strain. Infect Immun. 1997 Jul; 65(7):2941-9.
    View in: PubMed
  139. Butterton JR, Ryan ET, Acheson DW, Calderwood SB. Coexpression of the B subunit of Shiga toxin 1 and EaeA from enterohemorrhagic Escherichia coli in Vibrio cholerae vaccine strains. Infect Immun. 1997 Jun; 65(6):2127-35.
    View in: PubMed
  140. Watnick PI, Eto T, Takahashi H, Calderwood SB. Purification of Vibrio cholerae fur and estimation of its intracellular abundance by antibody sandwich enzyme-linked immunosorbent assay. J Bacteriol. 1997 Jan; 179(1):243-7.
    View in: PubMed
  141. Carroll PA, Zhao G, Boyko SA, Winkler ME, Calderwood SB. Identification, sequencing, and enzymatic activity of the erythrose-4-phosphate dehydrogenase gene of Vibrio cholerae. J Bacteriol. 1997 Jan; 179(1):293-6.
    View in: PubMed
  142. Calderwood SB, Baker MA, Carroll PA, Michel JL, Arbeit RD, Ausubel FM. Use of cleaved amplified polymorphic sequences to distinguish strains of Staphylococcus epidermidis. J Clin Microbiol. 1996 Nov; 34(11):2860-5.
    View in: PubMed
  143. Butterton JR, Ryan ET, Shahin RA, Calderwood SB. Development of a germfree mouse model of Vibrio cholerae infection. Infect Immun. 1996 Oct; 64(10):4373-7.
    View in: PubMed
  144. Tashima KT, Carroll PA, Rogers MB, Calderwood SB. Relative importance of three iron-regulated outer membrane proteins for in vivo growth of Vibrio cholerae. Infect Immun. 1996 May; 64(5):1756-61.
    View in: PubMed
  145. Pozsgay V, Trinh L, Shiloach J, Robbins JB, Donohue-Rolfe A, Calderwood SB. Purification of subunit B of Shiga toxin using a synthetic trisaccharide-based affinity matrix. Bioconjug Chem. 1996 Jan-Feb; 7(1):45-55.
    View in: PubMed
  146. Kontoyiannis DP, Calia KE, Basgoz N, Calderwood SB. Primary septicemia caused by Vibrio cholerae non-O1 acquired on Cape Cod, Massachusetts. Clin Infect Dis. 1995 Nov; 21(5):1330-3.
    View in: PubMed
  147. Butterton JR, Beattie DT, Gardel CL, Carroll PA, Hyman T, Killeen KP, Mekalanos JJ, Calderwood SB. Heterologous antigen expression in Vibrio cholerae vector strains. Infect Immun. 1995 Jul; 63(7):2689-96.
    View in: PubMed
  148. Butterton JR, Calderwood SB. Identification, cloning, and sequencing of a gene required for ferric vibriobactin utilization by Vibrio cholerae. J Bacteriol. 1994 Sep; 176(18):5631-8.
    View in: PubMed
  149. Lam MS, Litwin CM, Carroll PA, Calderwood SB. Vibrio cholerae fur mutations associated with loss of repressor activity: implications for the structural-functional relationships of fur. J Bacteriol. 1994 Aug; 176(16):5108-15.
    View in: PubMed
  150. Calia KE, Murtagh M, Ferraro MJ, Calderwood SB. Comparison of Vibrio cholerae O139 with V. cholerae O1 classical and El Tor biotypes. Infect Immun. 1994 Apr; 62(4):1504-6.
    View in: PubMed
  151. Litwin CM, Calderwood SB. Analysis of the complexity of gene regulation by fur in Vibrio cholerae. J Bacteriol. 1994 Jan; 176(1):240-8.
    View in: PubMed
  152. Butterton JR, Boyko SA, Calderwood SB. Use of the Vibrio cholerae irgA gene as a locus for insertion and expression of heterologous antigens in cholera vaccine strains. Vaccine. 1993 Oct; 11(13):1327-35.
    View in: PubMed
  153. Litwin CM, Calderwood SB. Role of iron in regulation of virulence genes. Clin Microbiol Rev. 1993 Apr; 6(2):137-49.
    View in: PubMed
  154. Acheson DW, Calderwood SB, Boyko SA, Lincicome LL, Kane AV, Donohue-Rolfe A, Keusch GT. Comparison of Shiga-like toxin I B-subunit expression and localization in Escherichia coli and Vibrio cholerae by using trc or iron-regulated promoter systems. Infect Immun. 1993 Mar; 61(3):1098-104.
    View in: PubMed
  155. Litwin CM, Calderwood SB. Cloning and genetic analysis of the Vibrio vulnificus fur gene and construction of a fur mutant by in vivo marker exchange. J Bacteriol. 1993 Feb; 175(3):706-15.
    View in: PubMed
  156. Durand ML, Calderwood SB, Weber DJ, Miller SI, Southwick FS, Caviness VS, Swartz MN. Acute bacterial meningitis in adults. A review of 493 episodes. N Engl J Med. 1993 Jan 7; 328(1):21-8.
    View in: PubMed
  157. Goldberg MB, Boyko SA, Butterton JR, Stoebner JA, Payne SM, Calderwood SB. Characterization of a Vibrio cholerae virulence factor homologous to the family of TonB-dependent proteins. Mol Microbiol. 1992 Aug; 6(16):2407-18.
    View in: PubMed
  158. Butterton JR, Stoebner JA, Payne SM, Calderwood SB. Cloning, sequencing, and transcriptional regulation of viuA, the gene encoding the ferric vibriobactin receptor of Vibrio cholerae. J Bacteriol. 1992 Jun; 174(11):3729-38.
    View in: PubMed
  159. Stoebner JA, Butterton JR, Calderwood SB, Payne SM. Identification of the vibriobactin receptor of Vibrio cholerae. J Bacteriol. 1992 May; 174(10):3270-4.
    View in: PubMed
  160. Deresiewicz RL, Calderwood SB, Robertus JD, Collier RJ. Mutations affecting the activity of the Shiga-like toxin I A-chain. Biochemistry. 1992 Mar 31; 31(12):3272-80.
    View in: PubMed
  161. Litwin CM, Boyko SA, Calderwood SB. Cloning, sequencing, and transcriptional regulation of the Vibrio cholerae fur gene. J Bacteriol. 1992 Mar; 174(6):1897-903.
    View in: PubMed
  162. Hart PJ, Monzingo AF, Donohue-Rolfe A, Keusch GT, Calderwood SB, Robertus JD. Crystallization of the B chain of Shiga-like toxin I from Escherichia coli. J Mol Biol. 1991 Apr 20; 218(4):691-4.
    View in: PubMed
  163. Goldberg MB, Boyko SA, Calderwood SB. Positive transcriptional regulation of an iron-regulated virulence gene in Vibrio cholerae. Proc Natl Acad Sci U S A. 1991 Feb 15; 88(4):1125-9.
    View in: PubMed
  164. Rice LB, Calderwood SB, Eliopoulos GM, Farber BF, Karchmer AW. Enterococcal endocarditis: a comparison of prosthetic and native valve disease. Rev Infect Dis. 1991 Jan-Feb; 13(1):1-7.
    View in: PubMed
  165. Goldberg MB, Boyko SA, Calderwood SB. Transcriptional regulation by iron of a Vibrio cholerae virulence gene and homology of the gene to the Escherichia coli fur system. J Bacteriol. 1990 Dec; 172(12):6863-70.
    View in: PubMed
  166. Calderwood SB, Acheson DW, Goldberg MB, Boyko SA, Donohue-Rolfe A. A system for production and rapid purification of large amounts of the Shiga toxin/Shiga-like toxin I B subunit. Infect Immun. 1990 Sep; 58(9):2977-82.
    View in: PubMed
  167. Pearson GD, DiRita VJ, Goldberg MB, Boyko SA, Calderwood SB, Mekalanos JJ. New attenuated derivatives of Vibrio cholerae. Res Microbiol. 1990 Sep-Oct; 141(7-8):893-9.
    View in: PubMed
  168. Donnenberg MS, Calderwood SB, Donohue-Rolfe A, Keusch GT, Kaper JB. Construction and analysis of TnphoA mutants of enteropathogenic Escherichia coli unable to invade HEp-2 cells. Infect Immun. 1990 Jun; 58(6):1565-71.
    View in: PubMed
  169. Jackson MP, Deresiewicz RL, Calderwood SB. Mutational analysis of the Shiga toxin and Shiga-like toxin II enzymatic subunits. J Bacteriol. 1990 Jun; 172(6):3346-50.
    View in: PubMed
  170. Hunt C, Calderwood S. Characterization and sequence of a mouse hsp70 gene and its expression in mouse cell lines. Gene. 1990 Mar 15; 87(2):199-204.
    View in: PubMed
  171. Goldberg MB, DiRita VJ, Calderwood SB. Identification of an iron-regulated virulence determinant in Vibrio cholerae, using TnphoA mutagenesis. Infect Immun. 1990 Jan; 58(1):55-60.
    View in: PubMed
  172. Ruoff KL, Miller SI, Garner CV, Ferraro MJ, Calderwood SB. Bacteremia with Streptococcus bovis and Streptococcus salivarius: clinical correlates of more accurate identification of isolates. J Clin Microbiol. 1989 Feb; 27(2):305-8.
    View in: PubMed
  173. Hovde CJ, Calderwood SB, Mekalanos JJ, Collier RJ. Evidence that glutamic acid 167 is an active-site residue of Shiga-like toxin I. Proc Natl Acad Sci U S A. 1988 Apr; 85(8):2568-72.
    View in: PubMed
  174. Calderwood SB, Mekalanos JJ. Confirmation of the Fur operator site by insertion of a synthetic oligonucleotide into an operon fusion plasmid. J Bacteriol. 1988 Feb; 170(2):1015-7.
    View in: PubMed
  175. Calderwood SB, Mekalanos JJ. Iron regulation of Shiga-like toxin expression in Escherichia coli is mediated by the fur locus. J Bacteriol. 1987 Oct; 169(10):4759-64.
    View in: PubMed
  176. Caputo GM, Archer GL, Calderwood SB, DiNubile MJ, Karchmer AW. Native valve endocarditis due to coagulase-negative staphylococci. Clinical and microbiologic features. Am J Med. 1987 Oct; 83(4):619-25.
    View in: PubMed
  177. Calderwood SB, Auclair F, Donohue-Rolfe A, Keusch GT, Mekalanos JJ. Nucleotide sequence of the Shiga-like toxin genes of Escherichia coli. Proc Natl Acad Sci U S A. 1987 Jul; 84(13):4364-8.
    View in: PubMed
  178. Weber DJ, Calderwood SB, Karchmer AW, Pennington JE. Ampicillin versus cefamandole as initial therapy for community-acquired pneumonia. Antimicrob Agents Chemother. 1987 Jun; 31(6):876-82.
    View in: PubMed
  179. DiNubile MJ, Calderwood SB, Steinhaus DM, Karchmer AW. Cardiac conduction abnormalities complicating native valve active infective endocarditis. Am J Cardiol. 1986 Dec 1; 58(13):1213-7.
    View in: PubMed
  180. Calderwood SB, Swinski LA, Karchmer AW, Waternaux CM, Buckley MJ. Prosthetic valve endocarditis. Analysis of factors affecting outcome of therapy. J Thorac Cardiovasc Surg. 1986 Oct; 92(4):776-83.
    View in: PubMed
  181. Calderwood SB, Swinski LA, Waternaux CM, Karchmer AW, Buckley MJ. Risk factors for the development of prosthetic valve endocarditis. Circulation. 1985 Jul; 72(1):31-7.
    View in: PubMed
  182. Calderwood SB, Tung CC, Jackson E. Measurement of levels of aminoglycosides and vancomycin in serum in the presence of new beta-lactam antibiotics. J Clin Microbiol. 1984 May; 19(5):707-9.
    View in: PubMed
  183. Ruoff KL, Fishman JA, Calderwood SB, Kunz LJ. Distribution and incidence of viridans streptococcal species in routine clinical specimens. Am J Clin Pathol. 1983 Dec; 80(6):854-8.
    View in: PubMed
  184. Williamson R, Calderwood SB, Moellering RC, Tomasz A. Studies on the mechanism of intrinsic resistance to beta-lactam antibiotics in group D streptococci. J Gen Microbiol. 1983 Mar; 129(3):813-22.
    View in: PubMed
  185. Calderwood SB, Gardella A, Philippon AM, Jacoby GA, Moellering RC. Effects of azlocillin in combination with clavulanic acid, sulbactam, and N-formimidoyl thienamycin against beta-lactamase-producing, carbenicillin-resistant Pseudomonas aeruginosa. Antimicrob Agents Chemother. 1982 Aug; 22(2):266-71.
    View in: PubMed
  186. Calderwood SB, Wennersten C, Moellering RC. Resistance to antibiotic synergism in Streptococcus faecalis: further studies with amikacin and with a new amikacin derivative, 4'-deoxy, 6'-N-methylamikacin. Antimicrob Agents Chemother. 1981 Apr; 19(4):549-55.
    View in: PubMed
  187. Calderwood SB, Moellering RC. Common adverse effects of antibacterial agents on major organ systems. Surg Clin North Am. 1980 Feb; 60(1):65-81.
    View in: PubMed
Local representatives can answer questions about the Profiles website or help with editing a profile or issues with profile data. For assistance with this profile: HMS/HSDM faculty should contact Human Resources at faculty_serviceshms.harvard.edu.
Calderwood's Networks
Click the "See All" links for more information and interactive visualizations!
Concepts
See all (647) concept(s)
_
Co-Authors
See all (63) people
_
Similar People
See all (60) people
_
Same Department
Search Department
Physical Neighbors
_