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Philippe Grandjean, D.M.Sc., M.D.

TitleAdjunct Professor of Environmental Health
InstitutionHarvard School of Public Health
DepartmentEH - Environmental + Occupational Medicine + Epi
AddressHarvard School of Public Health
Landmark Ctr, East 3-110
401 Park Dr
Boston MA 02215
Phone617/384-8907

 Overview 
 overview
Dr. Grandjean is an environmental epidemiologist whose research focuses on the long-term impacts of developmental exposure to environmental chemicals. In the mid-1980s, he initiated studies on marine contaminants in the Faroe Islands, where prospective birth cohort studies at first emphasized neurotoxicity, especially from methylmercury. More recent projects have examined general development and immunotoxicity in birth cohort subjects followed so far up to age 22 years. The results have had substantial public policy impact and inspired downward revisions of methylmercury exposure limits internationally. Other studies in the Faroes target age-related functional deficits and degenerative diseases, such as Parkinson's disease and cardiovascular disease, in regard to life-time exposure to methylmercury and persistent lipophilic contaminants. Research abroad also includes studies of pesticide neurotoxicity and endocrine disruption in children with prenatal exposures from their mother's work in greenhouses during pregnancy. Additional efforts relate to fluoride neurotoxicity; metal toxicology; biomarker development and validation; endocrine disruption caused by organochlorine substances; and carcinogenicity of exposure to zeolite and other mineral fibers. Occupational health studies have included research on percutaneous absorption of chemicals, carcinogenicity of fluoride exposure, and neurotoxicity of lead. Additional publications are on research ethics, genetic susceptibility, the setting of exposure limits, and the impact of the precautionary principle on prevention and research.


 Bibliographic 
 selected publications
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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  1. Julvez J, Grandjean P. Genetic susceptibility to methylmercury developmental neurotoxicity matters. Front Genet. 2013; 4:278.
    View in: PubMed
  2. Tang-Péronard JL, Heitmann BL, Andersen HR, Steuerwald U, Grandjean P, Weihe P, Jensen TK. Association between prenatal polychlorinated biphenyl exposure and obesity development at ages 5 and 7 y: a prospective cohort study of 656 children from the Faroe Islands. Am J Clin Nutr. 2014 Jan; 99(1):5-13.
    View in: PubMed
  3. Mozaffarian D, Shi P, Morris JS, Grandjean P, Siscovick DS, Spiegelman D, Hu FB. Methylmercury exposure and incident diabetes in u.s. Men and women in two prospective cohorts. Diabetes Care. 2013 Nov; 36(11):3578-84.
    View in: PubMed
  4. Julvez J, Smith GD, Golding J, Ring S, Pourcain BS, Gonzalez JR, Grandjean P. Prenatal methylmercury exposure and genetic predisposition to cognitive deficit at age 8 years. Epidemiology. 2013 Sep; 24(5):643-50.
    View in: PubMed
  5. Grandjean P, Ozonoff D. Transparency and translation of science in a modern world. Environ Health. 2013; 12(1):70.
    View in: PubMed
  6. Yorifuji T, Murata K, Bjerve KS, Choi AL, Weihe P, Grandjean P. Visual evoked potentials in children prenatally exposed to methylmercury. Neurotoxicology. 2013 Jul; 37:15-8.
    View in: PubMed
  7. Choi AL, Grandjean P, Sun G, Zhang Y. Developmental fluoride neurotoxicity: choi et Al. Respond. Environ Health Perspect. 2013 Mar 1; 121(3):a70.
    View in: PubMed
  8. Halling J, Petersen MS, Jørgensen N, Jensen TK, Grandjean P, Weihe P. Semen quality and reproductive hormones in Faroese men: a cross-sectional population-based study of 481 men. BMJ Open. 2013; 3(3).
    View in: PubMed
  9. Bellanger M, Pichery C, Aerts D, Berglund M, Castaño A, Cejchanová M, Crettaz P, Davidson F, Esteban M, Fischer ME, Gurzau AE, Halzlova K, Katsonouri A, Knudsen LE, Kolossa-Gehring M, Koppen G, Ligocka D, Miklavcic A, Reis MF, Rudnai P, Tratnik JS, Weihe P, Budtz-Jørgensen E, Grandjean P. Economic benefits of methylmercury exposure control in Europe: Monetary value of neurotoxicity prevention. Environ Health. 2013; 12(1):3.
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  10. Balbus JM, Barouki R, Birnbaum LS, Etzel RA, Gluckman PD, Grandjean P, Hancock C, Hanson MA, Heindel JJ, Hoffman K, Jensen GK, Keeling A, Neira M, Rabadán-Diehl C, Ralston J, Tang KC. Early-life prevention of non-communicable diseases. Lancet. 2013 Jan 5; 381(9860):3-4.
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  11. Dietz R, Sonne C, Basu N, Braune B, O'Hara T, Letcher RJ, Scheuhammer T, Andersen M, Andreasen C, Andriashek D, Asmund G, Aubail A, Baagøe H, Born EW, Chan HM, Derocher AE, Grandjean P, Knott K, Kirkegaard M, Krey A, Lunn N, Messier F, Obbard M, Olsen MT, Ostertag S, Peacock E, Renzoni A, Rigét FF, Skaare JU, Stern G, Stirling I, Taylor M, Wiig O, Wilson S, Aars J. What are the toxicological effects of mercury in Arctic biota? Sci Total Environ. 2013 Jan 15; 443:775-90.
    View in: PubMed
  12. Grandjean P, Pichery C, Bellanger M, Budtz-Jørgensen E. Calculation of Mercury's Effects on Neurodevelopment. Environ Health Perspect. 2012 Dec; 120(12):a452.
    View in: PubMed
  13. Wu H, Bertrand KA, Choi AL, Hu FB, Laden F, Grandjean P, Sun Q. Persistent Organic Pollutants and Type 2 Diabetes: A Prospective Analysis in the Nurses' Health Study and Meta-analysis. Environ Health Perspect. 2013 Feb; 121(2):153-61.
    View in: PubMed
  14. Grandjean P. [In Process Citation]. Ugeskr Laeger. 2012 Oct 29; 174(44):2693.
    View in: PubMed
  15. Schug TT, Barouki R, Gluckman PD, Grandjean P, Hanson M, Heindel JJ. PPTOX III: Environmental Stressors in the Developmental Origins of Disease--Evidence and Mechanisms. Toxicol Sci. 2013 Feb; 131(2):343-50.
    View in: PubMed
  16. Budtz-Jørgensen E, Bellinger D, Lanphear B, Grandjean P. An international pooled analysis for obtaining a benchmark dose for environmental lead exposure in children. Risk Anal. 2013 Mar; 33(3):450-61.
    View in: PubMed
  17. Pichery C, Bellanger M, Zmirou-Navier D, Fréry N, Cordier S, Roue-Legall A, Hartemann P, Grandjean P. Economic evaluation of health consequences of prenatal methylmercury exposure in France. Environ Health. 2012; 11:53.
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  18. Mozaffarian D, Shi P, Morris JS, Grandjean P, Siscovick DS, Spiegelman D, Willett WC, Rimm EB, Curhan GC, Forman JP. Mercury exposure and risk of hypertension in US men and women in 2 prospective cohorts. Hypertension. 2012 Sep; 60(3):645-52.
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  19. Grandjean P, Grønlund C, Kjær IM, Jensen TK, Sørensen N, Andersson AM, Juul A, Skakkebæk NE, Budtz-Jørgensen E, Weihe P. Reproductive hormone profile and pubertal development in 14-year-old boys prenatally exposed to polychlorinated biphenyls. Reprod Toxicol. 2012 Dec; 34(4):498-503.
    View in: PubMed
  20. Choi AL, Sun G, Zhang Y, Grandjean P. Developmental fluoride neurotoxicity: a systematic review and meta-analysis. Environ Health Perspect. 2012 Oct; 120(10):1362-8.
    View in: PubMed
  21. Barouki R, Gluckman PD, Grandjean P, Hanson M, Heindel JJ. Developmental origins of non-communicable disease: implications for research and public health. Environ Health. 2012; 11:42.
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  22. Færch K, Højlund K, Vind BF, Vaag A, Dalgård C, Nielsen F, Grandjean P. Increased serum concentrations of persistent organic pollutants among prediabetic individuals: potential role of altered substrate oxidation patterns. J Clin Endocrinol Metab. 2012 Sep; 97(9):E1705-13.
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  23. Grandjean P, Weihe P, Nielsen F, Heinzow B, Debes F, Budtz-Jørgensen E. Neurobehavioral deficits at age 7 years associated with prenatal exposure to toxicants from maternal seafood diet. Neurotoxicol Teratol. 2012 Jul; 34(4):466-72.
    View in: PubMed
  24. Andersen HR, Wohlfahrt-Veje C, Dalgård C, Christiansen L, Main KM, Nellemann C, Murata K, Jensen TK, Skakkebæk NE, Grandjean P. Paraoxonase 1 polymorphism and prenatal pesticide exposure associated with adverse cardiovascular risk profiles at school age. PLoS One. 2012; 7(5):e36830.
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  25. Grandjean P, Ozonoff D. Portrait of the journal as a young adult. Environ Health. 2012; 11:30.
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  26. Grandjean P, Andersen EW, Budtz-Jørgensen E, Nielsen F, Mølbak K, Weihe P, Heilmann C. Serum vaccine antibody concentrations in children exposed to perfluorinated compounds. JAMA. 2012 Jan 25; 307(4):391-7.
    View in: PubMed
  27. Karagas MR, Choi AL, Oken E, Horvat M, Schoeny R, Kamai E, Cowell W, Grandjean P, Korrick S. Evidence on the human health effects of low-level methylmercury exposure. Environ Health Perspect. 2012 Jun; 120(6):799-806.
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  28. London L, Beseler C, Bouchard MF, Bellinger DC, Colosio C, Grandjean P, Harari R, Kootbodien T, Kromhout H, Little F, Meijster T, Moretto A, Rohlman DS, Stallones L. Neurobehavioral and neurodevelopmental effects of pesticide exposures. Neurotoxicology. 2012 Aug; 33(4):887-96.
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  29. Vestergaard S, Nielsen F, Andersson AM, Hjøllund NH, Grandjean P, Andersen HR, Jensen TK. Association between perfluorinated compounds and time to pregnancy in a prospective cohort of Danish couples attempting to conceive. Hum Reprod. 2012 Mar; 27(3):873-80.
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  30. Fox DA, Grandjean P, de Groot D, Paule MG. Developmental origins of adult diseases and neurotoxicity: epidemiological and experimental studies. Neurotoxicology. 2012 Aug; 33(4):810-6.
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  31. Bal-Price AK, Coecke S, Costa L, Crofton KM, Fritsche E, Goldberg A, Grandjean P, Lein PJ, Li A, Lucchini R, Mundy WR, Padilla S, Persico AM, Seiler AE, Kreysa J. Advancing the science of developmental neurotoxicity (DNT): testing for better safety evaluation. ALTEX. 2012; 29(2):202-15.
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  32. Grandjean P. Strengths and limitations of HBM--imprecision matters. Int J Hyg Environ Health. 2012 Feb; 215(2):94.
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  33. Grandjean P, Eriksen ML, Ellegaard O, Wallin JA. The Matthew effect in environmental science publication: a bibliometric analysis of chemical substances in journal articles. Environ Health. 2011; 10:96.
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  34. Wohlfahrt-Veje C, Main KM, Schmidt IM, Boas M, Jensen TK, Grandjean P, Skakkebæk NE, Andersen HR. Lower birth weight and increased body fat at school age in children prenatally exposed to modern pesticides: a prospective study. Environ Health. 2011; 10:79.
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  35. Grandjean P. Larry Needham and the partition ratio. Chemosphere. 2011 Sep; 85(2):142.
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  36. Mahaffey KR, Sunderland EM, Chan HM, Choi AL, Grandjean P, Mariën K, Oken E, Sakamoto M, Schoeny R, Weihe P, Yan CH, Yasutake A. Balancing the benefits of n-3 polyunsaturated fatty acids and the risks of methylmercury exposure from fish consumption. Nutr Rev. 2011 Sep; 69(9):493-508.
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  37. Audouze K, Grandjean P. Application of computational systems biology to explore environmental toxicity hazards. Environ Health Perspect. 2011 Dec; 119(12):1754-9.
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  38. Julvez J, Debes F, Weihe P, Choi AL, Grandjean P. Thyroid dysfunction as a mediator of organochlorine neurotoxicity in preschool children. Environ Health Perspect. 2011 Oct; 119(10):1429-35.
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  39. Pichery C, Bellanger M, Zmirou-Navier D, Glorennec P, Hartemann P, Grandjean P. Childhood lead exposure in France: benefit estimation and partial cost-benefit analysis of lead hazard control. Environ Health. 2011; 10:44.
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  40. Grandjean P, Henriksen JE, Choi AL, Petersen MS, Dalgård C, Nielsen F, Weihe P. Marine food pollutants as a risk factor for hypoinsulinemia and type 2 diabetes. Epidemiology. 2011 May; 22(3):410-7.
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  41. White RF, Palumbo CL, Yurgelun-Todd DA, Heaton KJ, Weihe P, Debes F, Grandjean P. Functional MRI approach to developmental methylmercury and polychlorinated biphenyl neurotoxicity. Neurotoxicology. 2011 Dec; 32(6):975-80.
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  42. Dalgård C, Petersen MS, Weihe P, Grandjean P. Vitamin D status in relation to glucose metabolism and type 2 diabetes in septuagenarians. Diabetes Care. 2011 Jun; 34(6):1284-8.
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  43. Mozaffarian D, Shi P, Morris JS, Spiegelman D, Grandjean P, Siscovick DS, Willett WC, Rimm EB. Mercury exposure and risk of cardiovascular disease in two U.S. cohorts. N Engl J Med. 2011 Mar 24; 364(12):1116-25.
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  44. Kirkegaard M, Sonne C, Dietz R, Letcher RJ, Jensen AL, Hansen SS, Jenssen BM, Grandjean P. Alterations in thyroid hormone status in Greenland sledge dogs exposed to whale blubber contaminated with organohalogen compounds. Ecotoxicol Environ Saf. 2011 Jan; 74(1):157-63.
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  45. Grandjean P, Herz KT. Methylmercury and brain development: imprecision and underestimation of developmental neurotoxicity in humans. Mt Sinai J Med. 2011 Jan-Feb; 78(1):107-18.
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  46. Needham LL, Grandjean P, Heinzow B, Jørgensen PJ, Nielsen F, Patterson DG, Sjödin A, Turner WE, Weihe P. Partition of environmental chemicals between maternal and fetal blood and tissues. Environ Sci Technol. 2011 Feb 1; 45(3):1121-6.
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  47. Darney S, Fowler B, Grandjean P, Heindel J, Mattison D, Slikker W. Prenatal Programming and Toxicity II (PPTOX II): role of environmental stressors in the developmental origins of disease. Reprod Toxicol. 2011 Apr; 31(3):271.
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  48. Lincoln RA, Shine JP, Chesney EJ, Vorhees DJ, Grandjean P, Senn DB. Fish consumption and mercury exposure among Louisiana recreational anglers. Environ Health Perspect. 2011 Feb; 119(2):245-51.
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  49. Yorifuji T, Tsuda T, Doi H, Grandjean P. Cancer excess after arsenic exposure from contaminated milk powder. Environ Health Prev Med. 2011 May; 16(3):164-70.
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  50. Yorifuji T, Debes F, Weihe P, Grandjean P. Prenatal exposure to lead and cognitive deficit in 7- and 14-year-old children in the presence of concomitant exposure to similar molar concentration of methylmercury. Neurotoxicol Teratol. 2011 Mar-Apr; 33(2):205-11.
    View in: PubMed
  51. Grandjean P. Even low-dose lead exposure is hazardous. Lancet. 2010 Sep 11; 376(9744):855-6.
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  52. Julvez J, Debes F, Weihe P, Choi A, Grandjean P. Sensitivity of continuous performance test (CPT) at age 14 years to developmental methylmercury exposure. Neurotoxicol Teratol. 2010 Nov-Dec; 32(6):627-32.
    View in: PubMed
  53. Budtz-Jørgensen E, Debes F, Weihe P, Grandjean P. Structural equation models for meta-analysis in environmental risk assessment. Environmetrics. 2010 Aug 1; 21(5):510-527.
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  54. Spulber S, Rantamäki T, Nikkilä O, Castrén E, Weihe P, Grandjean P, Ceccatelli S. Effects of maternal smoking and exposure to methylmercury on brain-derived neurotrophic factor concentrations in umbilical cord serum. Toxicol Sci. 2010 Oct; 117(2):263-9.
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  55. Ozonoff DM, Grandjean P. Milestones and impact factors. Environ Health. 2010; 9:35.
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  56. Grandjean P, Satoh H, Murata K, Eto K. Adverse effects of methylmercury: environmental health research implications. Environ Health Perspect. 2010 Aug; 118(8):1137-45.
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  57. Grandjean P, Poulsen LK, Heilmann C, Steuerwald U, Weihe P. Allergy and sensitization during childhood associated with prenatal and lactational exposure to marine pollutants. Environ Health Perspect. 2010 Oct; 118(10):1429-33.
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  58. Heilmann C, Budtz-Jørgensen E, Nielsen F, Heinzow B, Weihe P, Grandjean P. Serum concentrations of antibodies against vaccine toxoids in children exposed perinatally to immunotoxicants. Environ Health Perspect. 2010 Oct; 118(10):1434-8.
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  59. Dalgård C, Petersen MS, Schmedes AV, Brandslund I, Weihe P, Grandjean P. High latitude and marine diet: vitamin D status in elderly Faroese. Br J Nutr. 2010 Sep; 104(6):914-8.
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  60. Schlezinger JJ, Bernard PL, Haas A, Grandjean P, Weihe P, Sherr DH. Direct assessment of cumulative aryl hydrocarbon receptor agonist activity in sera from experimentally exposed mice and environmentally exposed humans. Environ Health Perspect. 2010 May; 118(5):693-8.
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  61. Takaro TK, Davis D, Van Rensburg SJ, Arroyo Aguilar RS, Algranti E, Bailar JC, Belpoggi F, Berlin M, Bhattacharya S, Bonnier Viger YV, Brophy J, Bustinza R, Cameron RB, Dement JM, Egilman D, Castleman B, Chaturvedi S, Cherniack M, Choudhury H, Demers PA, Digangi J, Digon A, Edwards JG, Englund A, Erikson B, Corréa Filho HR, Franco G, Frank AL, Freund A, Gee D, Giordano A, Gochfeld M, Gilberg M, Goldsmith DF, Goldstein BD, Grandjean P, Greenberg M, Gut I, Harari R, Hindry M, Hogstedt C, Huff J, Infante PF, Järvholm B, Kern DG, Keifer M, Khatter K, Kjuus H, Keith M, Koo LC, Kumar A, LaDou J, Landrigan PJ, Lemen RA, Last JM, Lee CW, Leigh J, Levin SM, Lippman A, Madrid GA, McCulloch J, McDiarmid MA, Merchant JA, Monforton C, Morse T, Muir DC, Mukerjee D, Mulloy KB, Myers J, Nuwayhid I, Orris P, Ozonoff D, Paek D, Patra M, Pelclová D, Pepper L, Poje GV, Rahman Q, Reyes B, Robinson BW, Rodríguez E, Rose C, Rosenman KD, Rosenstock L, Ruchirawat M, Rydzynski K, Schneider J, Silverstein B, Siqueira CE, Slatin C, Soffritti M, Soskoline C, Sparer J, Stayner LT, Takaro TK, Tarkowski S, Teitelbaum DT, Tompa A, Trosic I, Turcotte F, Vilela RA, Waterman YR, Watterson A, Wegman DH, Welch LS, Woitowitz HJ, Yanri Z, Zavariz C. Scientists appeal to Quebec Premier Charest to stop exporting asbestos to the developing world. Int J Occup Environ Health. 2010 Apr-Jun; 16(2):241-8.
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  62. Harari R, Julvez J, Murata K, Barr D, Bellinger DC, Debes F, Grandjean P. Neurobehavioral deficits and increased blood pressure in school-age children prenatally exposed to pesticides. Environ Health Perspect. 2010 Jun; 118(6):890-6.
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  63. Grandjean P, Budtz-Jørgensen E. An ignored risk factor in toxicology: The total imprecision of exposure assessment. Pure Appl Chem. 2010 Jan 25; 82(2):383-391.
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  64. Yorifuji T, Tsuda T, Grandjean P. Unusual cancer excess after neonatal arsenic exposure from contaminated milk powder. J Natl Cancer Inst. 2010 Mar 3; 102(5):360-1.
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  65. Blair A, Saracci R, Vineis P, Cocco P, Forastiere F, Grandjean P, Kogevinas M, Kriebel D, McMichael A, Pearce N, Porta M, Samet J, Sandler DP, Costantini AS, Vainio H. Epidemiology, public health, and the rhetoric of false positives. Environ Health Perspect. 2009 Dec; 117(12):1809-13.
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  66. Julvez J, Grandjean P. Neurodevelopmental toxicity risks due to occupational exposure to industrial chemicals during pregnancy. Ind Health. 2009 Oct; 47(5):459-68.
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  67. Pouzaud F, Ibbou A, Blanchemanche S, Grandjean P, Krempf M, Philippe HJ, Verger P. Use of advanced cluster analysis to characterize fish consumption patterns and methylmercury dietary exposures from fish and other sea foods among pregnant women. J Expo Sci Environ Epidemiol. 2010 Jan; 20(1):54-68.
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  68. Coccini T, Manzo L, Debes F, Steuerwald U, Weihe P, Grandjean P. No changes in lymphocyte muscarinic receptors and platelet monoamine oxidase-B examined as surrogate central nervous system biomarkers in a Faroese children cohort prenatally exposed to methylmercury and polychlorinated biphenyls. Biomarkers. 2009 Mar; 14(2):67-76.
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  69. Bjørling-Poulsen M, Andersen HR, Grandjean P. Potential developmental neurotoxicity of pesticides used in Europe. Environ Health. 2008; 7:50.
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  70. Chevrier C, Sullivan K, White RF, Comtois C, Cordier S, Grandjean P. Qualitative assessment of visuospatial errors in mercury-exposed Amazonian children. Neurotoxicology. 2009 Jan; 30(1):37-46.
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  71. Choi AL, Weihe P, Budtz-Jørgensen E, Jørgensen PJ, Salonen JT, Tuomainen TP, Murata K, Nielsen HP, Petersen MS, Askham J, Grandjean P. Methylmercury exposure and adverse cardiovascular effects in Faroese whaling men. Environ Health Perspect. 2009 Mar; 117(3):367-72.
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  72. Grandjean P, Heindel JJ. In utero and early-life conditions and adult health and disease. N Engl J Med. 2008 Oct 2; 359(14):1523; author reply 1524.
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  73. Grandjean P, Budtz-Jørgensen E, Barr DB, Needham LL, Weihe P, Heinzow B. Elimination half-lives of polychlorinated biphenyl congeners in children. Environ Sci Technol. 2008 Sep 15; 42(18):6991-6.
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  74. Weihe P, Kato K, Calafat AM, Nielsen F, Wanigatunga AA, Needham LL, Grandjean P. Serum concentrations of polyfluoroalkyl compounds in Faroese whale meat consumers. Environ Sci Technol. 2008 Aug 15; 42(16):6291-5.
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  75. Petersen MS, Weihe P, Choi A, Grandjean P. Increased prenatal exposure to methylmercury does not affect the risk of Parkinson's disease. Neurotoxicology. 2008 Jul; 29(4):591-5.
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  76. Andersen HR, Schmidt IM, Grandjean P, Jensen TK, Budtz-Jørgensen E, Kjaerstad MB, Baelum J, Nielsen JB, Skakkebaek NE, Main KM. Impaired reproductive development in sons of women occupationally exposed to pesticides during pregnancy. Environ Health Perspect. 2008 Apr; 116(4):566-72.
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  77. Petersen MS, Halling J, Bech S, Wermuth L, Weihe P, Nielsen F, Jørgensen PJ, Budtz-Jørgensen E, Grandjean P. Impact of dietary exposure to food contaminants on the risk of Parkinson's disease. Neurotoxicology. 2008 Jul; 29(4):584-90.
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  78. Halling J, Petersen MS, Grandjean P, Weihe P, Brosen K. Genetic predisposition to Parkinson's disease: CYP2D6 and HFE in the Faroe Islands. Pharmacogenet Genomics. 2008 Mar; 18(3):209-12.
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  79. Wermuth L, Bech S, Petersen MS, Joensen P, Weihe P, Grandjean P. Prevalence and incidence of Parkinson's disease in The Faroe Islands. Acta Neurol Scand. 2008 Aug; 118(2):126-31.
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  80. Grandjean P. Late insights into early origins of disease. Basic Clin Pharmacol Toxicol. 2008 Feb; 102(2):94-9.
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  81. Grandjean P, Weihe P. Developmental origins of environmentally induced disease and dysfunction International Conference on Foetal Programming and Developmental Toxicity, Tórshavn, Faroe Islands, 20-24 May, 2007. Basic Clin Pharmacol Toxicol. 2008 Feb; 102(2):71-2.
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  82. Grandjean P, Bellinger D, Bergman A, Cordier S, Davey-Smith G, Eskenazi B, Gee D, Gray K, Hanson M, van den Hazel P, Heindel JJ, Heinzow B, Hertz-Picciotto I, Hu H, Huang TT, Jensen TK, Landrigan PJ, McMillen IC, Murata K, Ritz B, Schoeters G, Skakkebaek NE, Skerfving S, Weihe P. The faroes statement: human health effects of developmental exposure to chemicals in our environment. Basic Clin Pharmacol Toxicol. 2008 Feb; 102(2):73-5.
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  83. Choi AL, Cordier S, Weihe P, Grandjean P. Negative confounding in the evaluation of toxicity: the case of methylmercury in fish and seafood. Crit Rev Toxicol. 2008; 38(10):877-93.
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  84. Grandjean P. Seven deadly sins of environmental epidemiology and the virtues of precaution. Epidemiology. 2008 Jan; 19(1):158-62.
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  85. Grandjean P, Choi A. The delayed appearance of a mercurial warning. Epidemiology. 2008 Jan; 19(1):10-1.
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  86. Landrigan P, Nordberg M, Lucchini R, Nordberg G, Grandjean P, Iregren A, Alessio L. The Declaration of Brescia on prevention of the neurotoxicity of metals June 18, 2006. Am J Ind Med. 2007 Oct; 50(10):709-11.
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  87. Murata K, Grandjean P, Dakeishi M. Neurophysiological evidence of methylmercury neurotoxicity. Am J Ind Med. 2007 Oct; 50(10):765-71.
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  88. Grandjean P, Budtz-Jørgensen E. Total imprecision of exposure biomarkers: implications for calculating exposure limits. Am J Ind Med. 2007 Oct; 50(10):712-9.
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  89. Choi AL, Budtz-Jørgensen E, Jørgensen PJ, Steuerwald U, Debes F, Weihe P, Grandjean P. Selenium as a potential protective factor against mercury developmental neurotoxicity. Environ Res. 2008 May; 107(1):45-52.
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  90. Grandjean P, Ozonoff D. Environmental Health: the first five years. Environ Health. 2007; 6:27.
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  91. Grandjean P. [Effect of industrial chemicals on development of the nerve system--secondary publication]. Ugeskr Laeger. 2007 Aug 20; 169(34):2782-4.
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  92. Petersen MS, Halling J, Damkier P, Nielsen F, Grandjean P, Weihe P, Brøsen K. Polychlorinated biphenyl (PCB) induction of CYP3A4 enzyme activity in healthy Faroese adults. Toxicol Appl Pharmacol. 2007 Oct 15; 224(2):202-6.
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  93. Andersen HR, Nielsen F, Nielsen JB, Kjaerstad MB, Baelum J, Grandjean P. Xeno-oestrogenic activity in serum as marker of occupational pesticide exposure. Occup Environ Med. 2007 Oct; 64(10):708-14.
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  94. Grandjean P. Methylmercury toxicity and functional programming. Reprod Toxicol. 2007 Apr-May; 23(3):414-20.
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  95. Grandjean P, Murata K. Developmental arsenic neurotoxicity in retrospect. Epidemiology. 2007 Jan; 18(1):25-6.
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  96. Grandjean P, Landrigan PJ. Developmental neurotoxicity of industrial chemicals. Lancet. 2006 Dec 16; 368(9553):2167-78.
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  97. Budtz-Jørgensen E, Grandjean P, Weihe P. Separation of risks and benefits of seafood intake. Environ Health Perspect. 2007 Mar; 115(3):323-7.
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  98. Petersen MS, Halling J, Damkier P, Nielsen F, Grandjean P, Weihe P, Brøsen K. Caffeine N3-demethylation (CYP1A2) in a population with an increased exposure to polychlorinated biphenyls. Eur J Clin Pharmacol. 2006 Dec; 62(12):1041-8.
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  99. Landrigan P, Nordberg M, Lucchini R, Nordberg G, Grandjean P, Iregren A, Alessio L. The Declaration of Brescia on Prevention of the Neurotoxicity of Metals Brescia, Italia 17-18 June 2006. Med Lav. 2006 Nov-Dec; 97(6):811-4.
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  100. Dakeishi M, Murata K, Grandjean P. Long-term consequences of arsenic poisoning during infancy due to contaminated milk powder. Environ Health. 2006; 5:31.
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  101. Budtz-Jørgensen E, Keiding N, Grandjean P, Weihe P. Confounder selection in environmental epidemiology: assessment of health effects of prenatal mercury exposure. Ann Epidemiol. 2007 Jan; 17(1):27-35.
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  102. Murata K, Weihe P, Budtz-Jørgensen E, Jørgensen PJ, Grandjean P. Correction for "Delayed brainstem auditory evoked potential latencies in 14-year-old children exposed to methylmercury" by Murata et al. J Pediatr. 2006 Oct; 149(4):583-4.
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  103. Debes F, Budtz-Jørgensen E, Weihe P, White RF, Grandjean P. Impact of prenatal methylmercury exposure on neurobehavioral function at age 14 years. Neurotoxicol Teratol. 2006 Sep-Oct; 28(5):536-47.
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  104. Heilmann C, Grandjean P, Weihe P, Nielsen F, Budtz-Jørgensen E. Reduced antibody responses to vaccinations in children exposed to polychlorinated biphenyls. PLoS Med. 2006 Aug; 3(8):e311.
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  105. Debes F, Budtz-Jørgensen E, Weihe P, White RF, Grandjean P. Impact of prenatal methylmercury exposure on neurobehavioral function at age 14 years. Neurotoxicol Teratol. 2006 May-Jun; 28(3):363-75.
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  106. Baris YI, Grandjean P. Prospective study of mesothelioma mortality in Turkish villages with exposure to fibrous zeolite. J Natl Cancer Inst. 2006 Mar 15; 98(6):414-7.
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  107. Grandjean P, Harari R, Barr DB, Debes F. Pesticide exposure and stunting as independent predictors of neurobehavioral deficits in Ecuadorian school children. Pediatrics. 2006 Mar; 117(3):e546-56.
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  108. Dietz R, Riget F, Born EW, Sonne C, Grandjean P, Kirkegaard M, Olsen MT, Asmund G, Renzoni A, Baagøe H, Andreasen C. Trends in mercury in hair of Greenlandic polar bears (Ursus maritimus) during 1892-2001. Environ Sci Technol. 2006 Feb 15; 40(4):1120-5.
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  109. Coccini T, Randine G, Castoldi AF, Grandjean P, Ostendorp G, Heinzow B, Manzo L. Effects of developmental co-exposure to methylmercury and 2,2',4,4',5,5'-hexachlorobiphenyl (PCB153) on cholinergic muscarinic receptors in rat brain. Neurotoxicology. 2006 Jul; 27(4):468-77.
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  110. Fängström B, Hovander L, Bignert A, Athanassiadis I, Linderholm L, Grandjean P, Weihe P, Bergman A. Concentrations of polybrominated diphenyl ethers, polychlonnated biphenyls, and polychlorobiphenylols in serum from pregnant Faroese women and their children 7 years later. Environ Sci Technol. 2005 Dec 15; 39(24):9457-63.
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  111. Grandjean P. Contaminants in fish oil. Am J Clin Nutr. 2005 Dec; 82(6):1354; author reply 1354-5.
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  112. Barr DB, Weihe P, Davis MD, Needham LL, Grandjean P. Serum polychlorinated biphenyl and organochlorine insecticide concentrations in a Faroese birth cohort. Chemosphere. 2006 Feb; 62(7):1167-82.
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  113. Jensen TK, Grandjean P, Jørgensen EB, White RF, Debes F, Weihe P. Effects of breast feeding on neuropsychological development in a community with methylmercury exposure from seafood. J Expo Anal Environ Epidemiol. 2005 Sep; 15(5):423-30.
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  114. Grandjean P. Non-precautionary aspects of toxicology. Toxicol Appl Pharmacol. 2005 Sep 1; 207(2 Suppl):652-7.
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  115. Fängström B, Athanasiadou M, Athanassiadis I, Bignert A, Grandjean P, Weihe P, Bergman A. Polybrominated diphenyl ethers and traditional organochlorine pollutants in fulmars (Fulmarus glacialis) from the Faroe Islands. Chemosphere. 2005 Aug; 60(7):836-43.
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  116. Halling J, Petersen MS, Damkier P, Nielsen F, Grandjean P, Weihe P, Lundgren S, Lundblad MS, Brøsen K. Polymorphism of CYP2D6, CYP2C19, CYP2C9 and CYP2C8 in the Faroese population. Eur J Clin Pharmacol. 2005 Aug; 61(7):491-7.
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  117. Fängström B, Strid A, Grandjean P, Weihe P, Bergman A. A retrospective study of PBDEs and PCBs in human milk from the Faroe Islands. Environ Health. 2005; 4:12.
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  118. Grandjean P, Budtz-Jørgensen E, Jørgensen PJ, Weihe P. Umbilical cord mercury concentration as biomarker of prenatal exposure to methylmercury. Environ Health Perspect. 2005 Jul; 113(7):905-8.
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  119. Grandjean P, Klein G. Epidemiology and precaution 150 years before snow. Epidemiology. 2005 Mar; 16(2):271-2.
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  120. Weihe P, Grandjean P, Jørgensen PJ. Application of hair-mercury analysis to determine the impact of a seafood advisory. Environ Res. 2005 Feb; 97(2):200-7.
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  121. Grandjean P, Jørgensen PJ. Measuring mercury concentration. Epidemiology. 2005 Jan; 16(1):133.
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  122. Budtz-Jørgensen E, Keiding N, Grandjean P. Effects of exposure imprecision on estimation of the benchmark dose. Risk Anal. 2004 Dec; 24(6):1689-96.
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  123. Grandjean P, Jensen AA. Breastfeeding and the weanling's dilemma. Am J Public Health. 2004 Jul; 94(7):1075; author reply 1075-6.
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  124. Budtz-Jørgensen E, Grandjean P, Jørgensen PJ, Weihe P, Keiding N. Association between mercury concentrations in blood and hair in methylmercury-exposed subjects at different ages. Environ Res. 2004 Jul; 95(3):385-93.
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  125. Grandjean P, Olsen JH. Extended follow-up of cancer incidence in fluoride-exposed workers. J Natl Cancer Inst. 2004 May 19; 96(10):802-3.
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  126. Grandjean P, Bailar JC, Gee D, Needleman HL, Ozonoff DM, Richter E, Sofritti M, Soskolne CL. Implications of the Precautionary Principle in research and policy-making. Am J Ind Med. 2004 Apr; 45(4):382-5.
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  127. Nielsen JB, Grandjean P. Criteria for skin notation in different countries. Am J Ind Med. 2004 Mar; 45(3):275-80.
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  128. Grandjean P, Murata K, Budtz-Jørgensen E, Weihe P. Cardiac autonomic activity in methylmercury neurotoxicity: 14-year follow-up of a Faroese birth cohort. J Pediatr. 2004 Feb; 144(2):169-76.
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  129. Murata K, Weihe P, Budtz-Jørgensen E, Jørgensen PJ, Grandjean P. Delayed brainstem auditory evoked potential latencies in 14-year-old children exposed to methylmercury. J Pediatr. 2004 Feb; 144(2):177-83.
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  130. Grandjean P. Implications of the precautionary principle for primary prevention and research. Annu Rev Public Health. 2004; 25:199-223.
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  131. Grandjean P, Budtz-Jørgensen E, Keiding N, Weihe P. Underestimation of risk due to exposure misclassification. Int J Occup Med Environ Health. 2004; 17(1):131-6.
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  132. Budtz-Jørgensen E, Keiding N, Grandjean P, Weihe P, White RF. Consequences of exposure measurement error for confounder identification in environmental epidemiology. Stat Med. 2003 Oct 15; 22(19):3089-100.
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  133. Rasmussen TH, Nielsen F, Andersen HR, Nielsen JB, Weihe P, Grandjean P. Assessment of xenoestrogenic exposure by a biomarker approach: application of the E-Screen bioassay to determine estrogenic response of serum extracts. Environ Health. 2003 Oct 15; 2(1):12.
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  134. Keiding N, Budtz-Jørgensen E, Grandjean P. Prenatal methylmercury exposure in the Seychelles. Lancet. 2003 Aug 23; 362(9384):664-5; author reply 665.
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  135. Grandjean P. [When breast feeding was accused]. Ugeskr Laeger. 2003 Jun 2; 165(23):2413-5.
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  136. Grandjean P, Weihe P. Arachidonic acid status during pregnancy is associated with polychlorinated biphenyl exposure. Am J Clin Nutr. 2003 Mar; 77(3):715-9.
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  137. Grandjean P, Budtz-Jørgensen E, Steuerwald U, Heinzow B, Needham LL, Jørgensen PJ, Weihe P. Attenuated growth of breast-fed children exposed to increased concentrations of methylmercury and polychlorinated biphenyls. FASEB J. 2003 Apr; 17(6):699-701.
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  138. Grandjean P, White RF, Weihe P, Jørgensen PJ. Neurotoxic risk caused by stable and variable exposure to methylmercury from seafood. Ambul Pediatr. 2003 Jan-Feb; 3(1):18-23.
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  139. Longnecker MP, Wolff MS, Gladen BC, Brock JW, Grandjean P, Jacobson JL, Korrick SA, Rogan WJ, Weisglas-Kuperus N, Hertz-Picciotto I, Ayotte P, Stewart P, Winneke G, Charles MJ, Jacobson SW, Dewailly E, Boersma ER, Altshul LM, Heinzow B, Pagano JJ, Jensen AA. Comparison of polychlorinated biphenyl levels across studies of human neurodevelopment. Environ Health Perspect. 2003 Jan; 111(1):65-70.
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  140. Fängström B, Athanasiadou M, Grandjean P, Weihe P, Bergman A. Hydroxylated PCB metabolites and PCBs in serum from pregnant Faroese women. Environ Health Perspect. 2002 Sep; 110(9):895-9.
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  141. Grandjean P. [Semi-truths about semiconductors]. Ugeskr Laeger. 2002 Aug 12; 164(33):3868-9.
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  142. Murata K, Budtz-Jørgensen E, Grandjean P. Benchmark dose calculations for methylmercury-associated delays on evoked potential latencies in two cohorts of children. Risk Anal. 2002 Jun; 22(3):465-74.
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  143. Mol NM, Sørensen N, Weihe P, Andersson AM, Jørgensen N, Skakkebaek NE, Keiding N, Grandjean P. Spermaturia and serum hormone concentrations at the age of puberty in boys prenatally exposed to polychlorinated biphenyls. Eur J Endocrinol. 2002 Mar; 146(3):357-63.
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  144. Weihe P, Hansen JC, Murata K, Debes F, Jørgensen P, Steuerwald U, White RF, Grandjean P. Neurobehavioral performance of Inuit children with increased prenatal exposure to methylmercury. Int J Circumpolar Health. 2002 Feb; 61(1):41-9.
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  145. Grandjean PA, Austin L, Chan S, Terpstra B, Bourgeois IM. Dynamic cardiomyoplasty: clinical follow-up results. J Card Surg. 1991 Mar; 6(1 Suppl):80-8.
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  146. Kimbrough RD, Grandjean PA. Risk assessment: extrapolation to individual risk. Basic Life Sci. 1988; 43:245-53.
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