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Emery Neal Brown, PH.D., M.D.

TitleWarren M. Zapol Professor of Anaesthesia
InstitutionMassachusetts General Hospital
DepartmentAnaesthesia
AddressMassachusetts General Hospital
Anesthesia & Critical Care, Clinics 3
55 Fruit St
Boston MA 02114
Phone617/726-8786
Fax617/726-8410

 Mentoring 
 completed student projects

 Bibliographic 
 selected publications
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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  1. Mukamel EA, Pirondini E, Babadi B, Wong KF, Pierce ET, Harrell PG, Walsh JL, Salazar-Gomez AF, Cash SS, Eskandar EN, Weiner VS, Brown EN, Purdon PL. A Transition in Brain State during Propofol-Induced Unconsciousness. J Neurosci. 2014 Jan 15; 34(3):839-45.
    View in: PubMed
  2. Akeju O, Brown EN. Awakened by a sleeping pill. Elife. 2013; 2(0).
    View in: PubMed
  3. Citi L, Ba D, Brown EN, Barbieri R. Likelihood methods for point processes with refractoriness. Neural Comput. 2014 Feb; 26(2):237-63.
    View in: PubMed
  4. Shanechi MM, Chemali JJ, Liberman M, Solt K, Brown EN. A brain-machine interface for control of medically-induced coma. PLoS Comput Biol. 2013 Oct; 9(10):e1003284.
    View in: PubMed
  5. Ching S, Liberman MY, Chemali JJ, Westover MB, Kenny JD, Solt K, Purdon PL, Brown EN. Real-time Closed-loop Control in a Rodent Model of Medically Induced Coma Using Burst Suppression. Anesthesiology. 2013 Oct; 119(4):848-60.
    View in: PubMed
  6. Babadi B, Obregon-Henao G, Lamus C, Hämäläinen MS, Brown EN, Purdon PL. A Subspace Pursuit-based Iterative Greedy Hierarchical solution to the neuromagnetic inverse problem. Neuroimage. 2014 Feb 15; 87:427-43.
    View in: PubMed
  7. Chemali J, Ching S, Purdon PL, Solt K, Brown EN. Burst suppression probability algorithms: state-space methods for tracking EEG burst suppression. J Neural Eng. 2013 Oct; 10(5):056017.
    View in: PubMed
  8. Brown EN, Purdon PL. The aging brain and anesthesia. Curr Opin Anaesthesiol. 2013 Aug; 26(4):414-9.
    View in: PubMed
  9. Lewis LD, Ching S, Weiner VS, Peterfreund RA, Eskandar EN, Cash SS, Brown EN, Purdon PL. Local cortical dynamics of burst suppression in the anaesthetized brain. Brain. 2013 Sep; 136(Pt 9):2727-37.
    View in: PubMed
  10. Brandon Westover M, Shafi MM, Ching S, Chemali JJ, Purdon PL, Cash SS, Brown EN. Real-time segmentation of burst suppression patterns in critical care EEG monitoring. J Neurosci Methods. 2013 Sep 30; 219(1):131-41.
    View in: PubMed
  11. Vijayan S, Ching S, Purdon PL, Brown EN, Kopell NJ. Thalamocortical mechanisms for the anteriorization of alpha rhythms during propofol-induced unconsciousness. J Neurosci. 2013 Jul 3; 33(27):11070-5.
    View in: PubMed
  12. Westover MB, Ching S, Shafi MM, Cash SS, Brown EN. Real-time segmentation and tracking of brain metabolic state in ICU EEG recordings of burst suppression. Conf Proc IEEE Eng Med Biol Soc. 2013 Jul; 2013:7108-11.
    View in: PubMed
  13. Krishnaswamy P, Bonmassar G, Purdon PL, Brown EN. Reference-free harmonic regression technique to remove EEG-fMRI ballistocardiogram artifacts. Conf Proc IEEE Eng Med Biol Soc. 2013 Jul; 2013:5426-9.
    View in: PubMed
  14. Shanechi MM, Chemali JJ, Liberman M, Solt K, Brown EN. A brain-machine interface for control of burst suppression in medical coma. Conf Proc IEEE Eng Med Biol Soc. 2013 Jul; 2013:1575-8.
    View in: PubMed
  15. Liberman MY, Ching S, Chemali J, Brown EN. A closed-loop anesthetic delivery system for real-time control of burst suppression. J Neural Eng. 2013 Aug; 10(4):046004.
    View in: PubMed
  16. Shanechi MM, Williams ZM, Wornell GW, Hu RC, Powers M, Brown EN. A real-time brain-machine interface combining motor target and trajectory intent using an optimal feedback control design. PLoS One. 2013; 8(4):e59049.
    View in: PubMed
  17. Purdon PL, Pierce ET, Mukamel EA, Prerau MJ, Walsh JL, Wong KF, Salazar-Gomez AF, Harrell PG, Sampson AL, Cimenser A, Ching S, Kopell NJ, Tavares-Stoeckel C, Habeeb K, Merhar R, Brown EN. Electroencephalogram signatures of loss and recovery of consciousness from propofol. Proc Natl Acad Sci U S A. 2013 Mar 19; 110(12):E1142-51.
    View in: PubMed
  18. Taylor NE, Chemali JJ, Brown EN, Solt K. Activation of D1 dopamine receptors induces emergence from isoflurane general anesthesia. Anesthesiology. 2013 Jan; 118(1):30-9.
    View in: PubMed
  19. Schwinn DA, Mackensen GB, Brown EN. Understanding the TXA seizure connection. J Clin Invest. 2012 Dec 3; 122(12):4339-41.
    View in: PubMed
  20. Shanechi MM, Hu RC, Powers M, Wornell GW, Brown EN, Williams ZM. Neural population partitioning and a concurrent brain-machine interface for sequential motor function. Nat Neurosci. 2012 Nov; 15(12):1715-22.
    View in: PubMed
  21. Lewis LD, Weiner VS, Mukamel EA, Donoghue JA, Eskandar EN, Madsen JR, Anderson WS, Hochberg LR, Cash SS, Brown EN, Purdon PL. Rapid fragmentation of neuronal networks at the onset of propofol-induced unconsciousness. Proc Natl Acad Sci U S A. 2012 Dec 4; 109(49):E3377-86.
    View in: PubMed
  22. Wong KF, Gong JJ, Cotten JF, Solt K, Brown EN. Assessing the effects of pharmacological agents on respiratory dynamics using time-series modeling. IEEE Trans Biomed Eng. 2013 Apr; 60(4):1118-25.
    View in: PubMed
  23. Brown EN, Solt K. Management of opioid analgesic overdose. N Engl J Med. 2012 Oct 4; 367(14):1370-1; author reply 1372-3.
    View in: PubMed
  24. Shanechi MM, Wornell GW, Williams ZM, Brown EN. Feedback-controlled parallel point process filter for estimation of goal-directed movements from neural signals. IEEE Trans Neural Syst Rehabil Eng. 2013 Jan; 21(1):129-40.
    View in: PubMed
  25. Ching S, Brown EN, Kramer MA. Distributed control in a mean-field cortical network model: implications for seizure suppression. Phys Rev E Stat Nonlin Soft Matter Phys. 2012 Aug; 86(2 Pt 1):021920.
    View in: PubMed
  26. Citi L, Brown EN, Barbieri R. A real-time automated point-process method for the detection and correction of erroneous and ectopic heartbeats. IEEE Trans Biomed Eng. 2012 Oct; 59(10):2828-37.
    View in: PubMed
  27. Citi L, Valenza G, Purdon PL, Brown EN, Barbieri R. Monitoring heartbeat nonlinear dynamics during general anesthesia by using the instantaneous dominant Lyapunov exponent. Conf Proc IEEE Eng Med Biol Soc. 2012 Aug; 2012:3124-7.
    View in: PubMed
  28. Sarma SV, Cheng ML, Eden U, Williams Z, Brown EN, Eskandar E. The effects of cues on neurons in the basal ganglia in Parkinson's disease. Front Integr Neurosci. 2012; 6:40.
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  29. Haslinger R, Pipa G, Lima B, Singer W, Brown EN, Neuenschwander S. Context matters: the illusive simplicity of macaque V1 receptive fields. PLoS One. 2012; 7(7):e39699.
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  30. Pipa G, Chen Z, Neuenschwander S, Lima B, Brown EN. Mapping of visual receptive fields by tomographic reconstruction. Neural Comput. 2012 Oct; 24(10):2543-78.
    View in: PubMed
  31. Chemali JJ, Van Dort CJ, Brown EN, Solt K. Active emergence from propofol general anesthesia is induced by methylphenidate. Anesthesiology. 2012 May; 116(5):998-1005.
    View in: PubMed
  32. Temereanca S, Hämäläinen MS, Kuperberg GR, Stufflebeam SM, Halgren E, Brown EN. Eye movements modulate the spatiotemporal dynamics of word processing. J Neurosci. 2012 Mar 28; 32(13):4482-94.
    View in: PubMed
  33. Shimazaki H, Amari S, Brown EN, Grün S. State-space analysis of time-varying higher-order spike correlation for multiple neural spike train data. PLoS Comput Biol. 2012; 8(3):e1002385.
    View in: PubMed
  34. Kodituwakku S, Lazar SW, Indic P, Chen Z, Brown EN, Barbieri R. Point process time-frequency analysis of dynamic respiratory patterns during meditation practice. Med Biol Eng Comput. 2012 Mar; 50(3):261-75.
    View in: PubMed
  35. Ching S, Purdon PL, Vijayan S, Kopell NJ, Brown EN. A neurophysiological-metabolic model for burst suppression. Proc Natl Acad Sci U S A. 2012 Feb 21; 109(8):3095-100.
    View in: PubMed
  36. Chen Z, Kloosterman F, Brown EN, Wilson MA. Uncovering spatial topology represented by rat hippocampal population neuronal codes. J Comput Neurosci. 2012 Oct; 33(2):227-55.
    View in: PubMed
  37. Jarosiewicz B, Schummers J, Malik WQ, Brown EN, Sur M. Functional biases in visual cortex neurons with identified projections to higher cortical targets. Curr Biol. 2012 Feb 21; 22(4):269-77.
    View in: PubMed
  38. Chen Z, Purdon PL, Brown EN, Barbieri R. A unified point process probabilistic framework to assess heartbeat dynamics and autonomic cardiovascular control. Front Physiol. 2012; 3:4.
    View in: PubMed
  39. Faghih RT, Savla K, Dahleh MA, Brown EN. Broad range of neural dynamics from a time-varying FitzHugh-Nagumo model and its spiking threshold estimation. IEEE Trans Biomed Eng. 2012 Mar; 59(3):816-23.
    View in: PubMed
  40. Lamus C, Hämäläinen MS, Temereanca S, Brown EN, Purdon PL. A spatiotemporal dynamic distributed solution to the MEG inverse problem. Neuroimage. 2012 Nov 1; 63(2):894-909.
    View in: PubMed
  41. Putrino DF, Chen Z, Ghosh S, Brown EN. Motor cortical networks for skilled movements have dynamic properties that are related to accurate reaching. Neural Plast. 2011; 2011:413543.
    View in: PubMed
  42. Solt K, Cotten JF, Cimenser A, Wong KF, Chemali JJ, Brown EN. Methylphenidate actively induces emergence from general anesthesia. Anesthesiology. 2011 Oct; 115(4):791-803.
    View in: PubMed
  43. Phillips MA, Colonnese MT, Goldberg J, Lewis LD, Brown EN, Constantine-Paton M. A synaptic strategy for consolidation of convergent visuotopic maps. Neuron. 2011 Aug 25; 71(4):710-24.
    View in: PubMed
  44. Sarma SV, Nguyen DP, Czanner G, Wirth S, Wilson MA, Suzuki W, Brown EN. Computing confidence intervals for point process models. Neural Comput. 2011 Nov; 23(11):2731-45.
    View in: PubMed
  45. Brooks D, Brown EN, Casler R, Fantini S, Khademhosseini A, Niemi J, Ramachandran R, Rutkove S, Tracey B. Boston research takes center stage. Interview by Pamela Reynolds. IEEE Pulse. 2011 Jul-Aug; 2(4):31-8.
    View in: PubMed
  46. Malik WQ, Schummers J, Sur M, Brown EN. Denoising two-photon calcium imaging data. PLoS One. 2011; 6(6):e20490.
    View in: PubMed
  47. Cimenser A, Purdon PL, Pierce ET, Walsh JL, Salazar-Gomez AF, Harrell PG, Tavares-Stoeckel C, Habeeb K, Brown EN. Tracking brain states under general anesthesia by using global coherence analysis. Proc Natl Acad Sci U S A. 2011 May 24; 108(21):8832-7.
    View in: PubMed
  48. Indic P, Bloch-Salisbury E, Bednarek F, Brown EN, Paydarfar D, Barbieri R. Assessment of cardio-respiratory interactions in preterm infants by bivariate autoregressive modeling and surrogate data analysis. Early Hum Dev. 2011 Jul; 87(7):477-87.
    View in: PubMed
  49. LaCount LT, Barbieri R, Park K, Kim J, Brown EN, Kuo B, Napadow V. Static and dynamic autonomic response with increasing nausea perception. Aviat Space Environ Med. 2011 Apr; 82(4):424-33.
    View in: PubMed
  50. Truccolo W, Donoghue JA, Hochberg LR, Eskandar EN, Madsen JR, Anderson WS, Brown EN, Halgren E, Cash SS. Single-neuron dynamics in human focal epilepsy. Nat Neurosci. 2011 May; 14(5):635-41.
    View in: PubMed
  51. Kim S, Putrino D, Ghosh S, Brown EN. A Granger causality measure for point process models of ensemble neural spiking activity. PLoS Comput Biol. 2011 Mar; 7(3):e1001110.
    View in: PubMed
  52. Wu W, Chen Z, Gao S, Brown EN. A hierarchical Bayesian approach for learning sparse spatio-temporal decompositions of multichannel EEG. Neuroimage. 2011 Jun 15; 56(4):1929-45.
    View in: PubMed
  53. Krishnaswamy P, Brown EN, Herr HM. Human leg model predicts ankle muscle-tendon morphology, state, roles and energetics in walking. PLoS Comput Biol. 2011 Mar; 7(3):e1001107.
    View in: PubMed
  54. Plourde E, Delgutte B, Brown EN. A point process model for auditory neurons considering both their intrinsic dynamics and the spectrotemporal properties of an extrinsic signal. IEEE Trans Biomed Eng. 2011 Jun; 58(6):1507-10.
    View in: PubMed
  55. Barnes TD, Mao JB, Hu D, Kubota Y, Dreyer AA, Stamoulis C, Brown EN, Graybiel AM. Advance cueing produces enhanced action-boundary patterns of spike activity in the sensorimotor striatum. J Neurophysiol. 2011 Apr; 105(4):1861-78.
    View in: PubMed
  56. Gong JJ, Wong KF, Cotten JF, Solt K, Brown EN. Correcting for serial dependence in studies of respiratory dynamics. Conf Proc IEEE Eng Med Biol Soc. 2011; 2011:1721-4.
    View in: PubMed
  57. Brown EN, Purdon PL, Van Dort CJ. General anesthesia and altered states of arousal: a systems neuroscience analysis. Annu Rev Neurosci. 2011; 34:601-28.
    View in: PubMed
  58. Faghih RT, Savla K, Dahleh MA, Brown EN. A feedback control model for cortisol secretion. Conf Proc IEEE Eng Med Biol Soc. 2011; 2011:716-9.
    View in: PubMed
  59. Chen Z, Vijayan S, Ching S, Hale G, Flores FJ, Wilson MA, Brown EN. Assessing neuronal interactions of cell assemblies during general anesthesia. Conf Proc IEEE Eng Med Biol Soc. 2011; 2011:4175-8.
    View in: PubMed
  60. Chen Z, Citi L, Purdon PL, Brown EN, Barbieri R. Instantaneous assessment of autonomic cardiovascular control during general anesthesia. Conf Proc IEEE Eng Med Biol Soc. 2011; 2011:8444-7.
    View in: PubMed
  61. Zheng HW, Malik WQ, Runyan CA, Sur M, Brown EN. Modeling two-photon calcium fluorescence of episodic V1 recordings using multifrequency analysis. Conf Proc IEEE Eng Med Biol Soc. 2011; 2011:3016-9.
    View in: PubMed
  62. Mukamel EA, Wong KF, Prerau MJ, Brown EN, Purdon PL. Phase-based measures of cross-frequency coupling in brain electrical dynamics under general anesthesia. Conf Proc IEEE Eng Med Biol Soc. 2011; 2011:1981-4.
    View in: PubMed
  63. Wong KF, Smith AC, Pierce ET, Harrell PG, Walsh JL, Salazar AF, Tavares CL, Cimenser A, Prerau MJ, Mukamel EA, Sampson A, Purdon PL, Brown EN. Bayesian analysis of trinomial data in behavioral experiments and its application to human studies of general anesthesia. Conf Proc IEEE Eng Med Biol Soc. 2011; 2011:4705-8.
    View in: PubMed
  64. Wong KF, Mukamel EA, Salazar AF, Pierce ET, Harrell PG, Walsh JL, Sampson A, Brown EN, Purdon PL. Robust time-varying multivariate coherence estimation: application to electroencephalogram recordings during general anesthesia. Conf Proc IEEE Eng Med Biol Soc. 2011; 2011:4725-8.
    View in: PubMed
  65. Chemali JJ, Wong KF, Solt K, Brown EN. A state-space model of the burst suppression ratio. Conf Proc IEEE Eng Med Biol Soc. 2011; 2011:1431-4.
    View in: PubMed
  66. Citi L, Djilas M, Azevedo-Coste C, Yoshida K, Brown EN, Barbieri R. Point-process analysis of neural spiking activity of muscle spindles recorded from thin-film longitudinal intrafascicular electrodes. Conf Proc IEEE Eng Med Biol Soc. 2011; 2011:2311-4.
    View in: PubMed
  67. Brown EN, Lydic R, Schiff ND. General anesthesia, sleep, and coma. N Engl J Med. 2010 Dec 30; 363(27):2638-50.
    View in: PubMed
  68. Ching S, Cimenser A, Purdon PL, Brown EN, Kopell NJ. Thalamocortical model for a propofol-induced alpha-rhythm associated with loss of consciousness. Proc Natl Acad Sci U S A. 2010 Dec 28; 107(52):22665-70.
    View in: PubMed
  69. Malik WQ, Truccolo W, Brown EN, Hochberg LR. Efficient decoding with steady-state Kalman filter in neural interface systems. IEEE Trans Neural Syst Rehabil Eng. 2011 Feb; 19(1):25-34.
    View in: PubMed
  70. Chen Z, Purdon PL, Harrell G, Pierce ET, Walsh J, Brown EN, Barbieri R. Dynamic assessment of baroreflex control of heart rate during induction of propofol anesthesia using a point process method. Ann Biomed Eng. 2011 Jan; 39(1):260-76.
    View in: PubMed
  71. Chen Z, Putrino DF, Ghosh S, Barbieri R, Brown EN. Statistical inference for assessing functional connectivity of neuronal ensembles with sparse spiking data. IEEE Trans Neural Syst Rehabil Eng. 2011 Apr; 19(2):121-35.
    View in: PubMed
  72. Putrino D, Brown EN, Mastaglia FL, Ghosh S. Differential involvement of excitatory and inhibitory neurons of cat motor cortex in coincident spike activity related to behavioral context. J Neurosci. 2010 Jun 9; 30(23):8048-56.
    View in: PubMed
  73. Keller CJ, Truccolo W, Gale JT, Eskandar E, Thesen T, Carlson C, Devinsky O, Kuzniecky R, Doyle WK, Madsen JR, Schomer DL, Mehta AD, Brown EN, Hochberg LR, Ulbert I, Halgren E, Cash SS. Heterogeneous neuronal firing patterns during interictal epileptiform discharges in the human cortex. Brain. 2010 Jun; 133(Pt 6):1668-81.
    View in: PubMed
  74. Vijayan S, Hale GJ, Moore CI, Brown EN, Wilson M. Activity in the barrel cortex during active behavior and sleep. J Neurophysiol. 2010 Apr; 103(4):2074-84.
    View in: PubMed
  75. Chen Z, Brown EN, Barbieri R. Characterizing nonlinear heartbeat dynamics within a point process framework. IEEE Trans Biomed Eng. 2010 Jun; 57(6):1335-47.
    View in: PubMed
  76. Sarma SV, Eden UT, Cheng ML, Williams ZM, Hu R, Eskandar E, Brown EN. Using point process models to compare neural spiking activity in the subthalamic nucleus of Parkinson's patients and a healthy primate. IEEE Trans Biomed Eng. 2010 Jun; 57(6):1297-305.
    View in: PubMed
  77. Faghih RT, Savla K, Dahleh MA, Brown EN. The Fitzhugh-Nagumo model: Firing modes with time-varying parameters & parameter estimation. Conf Proc IEEE Eng Med Biol Soc. 2010; 2010:4116-9.
    View in: PubMed
  78. Kodituwakku S, Lazar SW, Indic P, Brown EN, Barbieri R. Point process time-frequency analysis of respiratory sinus arrhythmia under altered respiration dynamics. Conf Proc IEEE Eng Med Biol Soc. 2010; 2010:1622-5.
    View in: PubMed
  79. Chen Z, Purdon PL, Brown EN, Barbieri R. A differential autoregressive modeling approach within a point process framework for non-stationary heartbeat intervals analysis. Conf Proc IEEE Eng Med Biol Soc. 2010; 2010:3567-70.
    View in: PubMed
  80. Cajigas I, Goldsmith MT, Duschau-Wicke A, Riener R, Smith MA, Brown EN, Bonato P. Assessment of lower extremity motor adaptation via an extension of the force field adaptation paradigm. Conf Proc IEEE Eng Med Biol Soc. 2010; 2010:4522-5.
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  81. Mauri M, Magagnin V, Cipresso P, Mainardi L, Brown EN, Cerutti S, Villamira M, Barbieri R. Psychophysiological signals associated with affective states. Conf Proc IEEE Eng Med Biol Soc. 2010; 2010:3563-6.
    View in: PubMed
  82. Smith AC, Scalon JD, Wirth S, Yanike M, Suzuki WA, Brown EN. State-space algorithms for estimating spike rate functions. Comput Intell Neurosci. 2010; 426539.
    View in: PubMed
  83. Nguyen DP, Wilson MA, Brown EN, Barbieri R. Measuring instantaneous frequency of local field potential oscillations using the Kalman smoother. J Neurosci Methods. 2009 Nov 15; 184(2):365-74.
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  84. Smith AC, Shah SA, Hudson AE, Purpura KP, Victor JD, Brown EN, Schiff ND. A Bayesian statistical analysis of behavioral facilitation associated with deep brain stimulation. J Neurosci Methods. 2009 Oct 15; 183(2):267-76.
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  85. Chen Z, Vijayan S, Barbieri R, Wilson MA, Brown EN. Discrete- and continuous-time probabilistic models and algorithms for inferring neuronal UP and DOWN states. Neural Comput. 2009 Jul; 21(7):1797-862.
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  86. Nguyen DP, Kloosterman F, Barbieri R, Brown EN, Wilson MA. Characterizing the dynamic frequency structure of fast oscillations in the rodent hippocampus. Front Integr Neurosci. 2009; 3:11.
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  87. Scholz J, Triantafyllou C, Whitfield-Gabrieli S, Brown EN, Saxe R. Distinct regions of right temporo-parietal junction are selective for theory of mind and exogenous attention. PLoS One. 2009; 4(3):e4869.
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  88. Chen Z, Brown EN, Barbieri R. Assessment of autonomic control and respiratory sinus arrhythmia using point process models of human heart beat dynamics. IEEE Trans Biomed Eng. 2009 Jul; 56(7):1791-802.
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  89. Purdon PL, Pierce ET, Bonmassar G, Walsh J, Harrell PG, Kwo J, Deschler D, Barlow M, Merhar RC, Lamus C, Mullaly CM, Sullivan M, Maginnis S, Skoniecki D, Higgins HA, Brown EN. Simultaneous electroencephalography and functional magnetic resonance imaging of general anesthesia. Ann N Y Acad Sci. 2009 Mar; 1157:61-70.
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  90. Chen Z, Putrino DF, Ba DE, Ghosh S, Barbieri R, Brown EN. A regularized point process generalized linear model for assessing the functional connectivity in the cat motor cortex. Conf Proc IEEE Eng Med Biol Soc. 2009; 2009:5006-9.
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  91. Chen Z, Purdon PL, Pierce ET, Harrell G, Walsh J, Salazar AF, Tavares CL, Brown EN, Barbieri R. Linear and nonlinear quantification of respiratory sinus arrhythmia during propofol general anesthesia. Conf Proc IEEE Eng Med Biol Soc. 2009; 2009:5336-9.
    View in: PubMed
  92. Malik WQ, Schummers J, Sur M, Brown EN. A statistical model for multiphoton calcium imaging of the brain. Conf Proc IEEE Eng Med Biol Soc. 2009; 2009:7002-5.
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  93. Wu W, Chen Z, Gao S, Brown EN. A probabilistic framework for learning robust common spatial patterns. Conf Proc IEEE Eng Med Biol Soc. 2009; 2009:4658-61.
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  94. McCarthy MM, Brown EN, Kopell N. Potential network mechanisms mediating electroencephalographic beta rhythm changes during propofol-induced paradoxical excitation. J Neurosci. 2008 Dec 10; 28(50):13488-504.
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  95. Temereanca S, Brown EN, Simons DJ. Rapid changes in thalamic firing synchrony during repetitive whisker stimulation. J Neurosci. 2008 Oct 29; 28(44):11153-64.
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  96. Yanike M, Wirth S, Smith AC, Brown EN, Suzuki WA. Comparison of associative learning-related signals in the macaque perirhinal cortex and hippocampus. Cereb Cortex. 2009 May; 19(5):1064-78.
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  97. Napadow V, Dhond R, Conti G, Makris N, Brown EN, Barbieri R. Brain correlates of autonomic modulation: combining heart rate variability with fMRI. Neuroimage. 2008 Aug 1; 42(1):169-77.
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  98. Barbieri R, Brown EN. Application of dynamic point process models to cardiovascular control. Biosystems. 2008 Jul-Aug; 93(1-2):120-5.
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  99. Czanner G, Eden UT, Wirth S, Yanike M, Suzuki WA, Brown EN. Analysis of between-trial and within-trial neural spiking dynamics. J Neurophysiol. 2008 May; 99(5):2672-93.
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  100. Chen Z, Brown EN, Barbieri R. Characterizing nonlinear heartbeat dynamics within a point process framework. Conf Proc IEEE Eng Med Biol Soc. 2008; 2008:2781-4.
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  101. Barbieri R, Chen Z, Brown EN. Assessment of hippocampal and autonomic neural activity by point process models. Conf Proc IEEE Eng Med Biol Soc. 2008; 2008:3679.
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  102. Nguyen DP, Barbieri R, Wilson MA, Brown EN. Instantaneous frequency and amplitude modulation of EEG in the hippocampus reveals state dependent temporal structure. Conf Proc IEEE Eng Med Biol Soc. 2008; 2008:1711-5.
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  103. Zhang Q, Brown EN, Strangman GE. Adaptive filtering to reduce global interference in evoked brain activity detection: a human subject case study. J Biomed Opt. 2007 Nov-Dec; 12(6):064009.
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  104. Zhang Q, Brown EN, Strangman GE. Adaptive filtering for global interference cancellation and real-time recovery of evoked brain activity: a Monte Carlo simulation study. J Biomed Opt. 2007 Jul-Aug; 12(4):044014.
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  105. Srinivasan L, Eden UT, Mitter SK, Brown EN. General-purpose filter design for neural prosthetic devices. J Neurophysiol. 2007 Oct; 98(4):2456-75.
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  106. Behn CG, Brown EN, Scammell TE, Kopell NJ. Mathematical model of network dynamics governing mouse sleep-wake behavior. J Neurophysiol. 2007 Jun; 97(6):3828-40.
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  107. Ergün A, Barbieri R, Eden UT, Wilson MA, Brown EN. Construction of point process adaptive filter algorithms for neural systems using sequential Monte Carlo methods. IEEE Trans Biomed Eng. 2007 Mar; 54(3):419-28.
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  108. Srinivasan L, Brown EN. A state-space framework for movement control to dynamic goals through brain-driven interfaces. IEEE Trans Biomed Eng. 2007 Mar; 54(3):526-35.
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  109. Smith AC, Wirth S, Suzuki WA, Brown EN. Bayesian analysis of interleaved learning and response bias in behavioral experiments. J Neurophysiol. 2007 Mar; 97(3):2516-24.
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  110. Srinivasan L, Eden UT, Willsky AS, Brown EN. A state-space analysis for reconstruction of goal-directed movements using neural signals. Neural Comput. 2006 Oct; 18(10):2465-94.
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  111. Karameh FN, Dahleh MA, Brown EN, Massaquoi SG. Modeling the contribution of lamina 5 neuronal and network dynamics to low frequency EEG phenomena. Biol Cybern. 2006 Oct; 95(4):289-310.
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  112. Scotti S, Mauri M, Barbieri R, Jawad B, Cerutti S, Mainardi L, Brown EN, Villamira MA. Automatic quantitative evaluation of emotions in E-learning applications. Conf Proc IEEE Eng Med Biol Soc. 2006; 1:1359-62.
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  113. Frank LM, Brown EN, Stanley GB. Hippocampal and cortical place cell plasticity: implications for episodic memory. Hippocampus. 2006; 16(9):775-84.
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  114. Barbieri R, Brown EN. Analysis of heartbeat dynamics by point process adaptive filtering. IEEE Trans Biomed Eng. 2006 Jan; 53(1):4-12.
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  115. Barbieri R, Brown EN. Correction of erroneous and ectopic beats using a point process adaptive algorithm. Conf Proc IEEE Eng Med Biol Soc. 2006; 1:3373-6.
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  116. Lee WC, Huang H, Feng G, Sanes JR, Brown EN, So PT, Nedivi E. Dynamic remodeling of dendritic arbors in GABAergic interneurons of adult visual cortex. PLoS Biol. 2006 Feb; 4(2):e29.
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  117. Indic P, Brown EN. Characterizing the amplitude dynamics of the human core-temperature circadian rhythm using a stochastic-dynamic model. J Theor Biol. 2006 Apr 21; 239(4):499-506.
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  118. Okatan M, Wilson MA, Brown EN. Analyzing functional connectivity using a network likelihood model of ensemble neural spiking activity. Neural Comput. 2005 Sep; 17(9):1927-61.
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  119. Kass RE, Ventura V, Brown EN. Statistical issues in the analysis of neuronal data. J Neurophysiol. 2005 Jul; 94(1):8-25.
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  120. Law JR, Flanery MA, Wirth S, Yanike M, Smith AC, Frank LM, Suzuki WA, Brown EN, Stark CE. Functional magnetic resonance imaging activity during the gradual acquisition and expression of paired-associate memory. J Neurosci. 2005 Jun 15; 25(24):5720-9.
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  121. Barbieri R, Wilson MA, Frank LM, Brown EN. An analysis of hippocampal spatio-temporal representations using a Bayesian algorithm for neural spike train decoding. IEEE Trans Neural Syst Rehabil Eng. 2005 Jun; 13(2):131-6.
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  122. Suzuki WA, Brown EN. Behavioral and neurophysiological analyses of dynamic learning processes. Behav Cogn Neurosci Rev. 2005 Jun; 4(2):67-95.
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  123. Indic P, Forger DB, St Hilaire MA, Dean DA, Brown EN, Kronauer RE, Klerman EB, Jewett ME. Comparison of amplitude recovery dynamics of two limit cycle oscillator models of the human circadian pacemaker. Chronobiol Int. 2005; 22(4):613-29.
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  124. Long C, Brown EN, Manoach D, Solo V. Spatiotemporal wavelet analysis for functional MRI. Neuroimage. 2004 Oct; 23(2):500-16.
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  125. Smith AC, Stefani MR, Moghaddam B, Brown EN. Analysis and design of behavioral experiments to characterize population learning. J Neurophysiol. 2005 Mar; 93(3):1776-92.
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  126. Barbieri R, Matten EC, Alabi AA, Brown EN. A point-process model of human heartbeat intervals: new definitions of heart rate and heart rate variability. Am J Physiol Heart Circ Physiol. 2005 Jan; 288(1):H424-35.
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  127. Truccolo W, Eden UT, Fellows MR, Donoghue JP, Brown EN. A point process framework for relating neural spiking activity to spiking history, neural ensemble, and extrinsic covariate effects. J Neurophysiol. 2005 Feb; 93(2):1074-89.
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  128. Frank LM, Stanley GB, Brown EN. Hippocampal plasticity across multiple days of exposure to novel environments. J Neurosci. 2004 Sep 1; 24(35):7681-9.
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  129. Brown EN, Kass RE, Mitra PP. Multiple neural spike train data analysis: state-of-the-art and future challenges. Nat Neurosci. 2004 May; 7(5):456-61.
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  130. Eden UT, Frank LM, Barbieri R, Solo V, Brown EN. Dynamic analysis of neural encoding by point process adaptive filtering. Neural Comput. 2004 May; 16(5):971-98.
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  131. Barbieri R, Frank LM, Nguyen DP, Quirk MC, Solo V, Wilson MA, Brown EN. Dynamic analyses of information encoding in neural ensembles. Neural Comput. 2004 Feb; 16(2):277-307.
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  132. Smith AC, Frank LM, Wirth S, Yanike M, Hu D, Kubota Y, Graybiel AM, Suzuki WA, Brown EN. Dynamic analysis of learning in behavioral experiments. J Neurosci. 2004 Jan 14; 24(2):447-61.
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  133. Brown EN, Solo V, Choe Y, Zhang Z. Measuring period of human biological clock: infill asymptotic analysis of harmonic regression parameter estimates. Methods Enzymol. 2004; 383:382-405.
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  134. Frank LM, Brown EN. Persistent activity and memory in the entorhinal cortex. Trends Neurosci. 2003 Aug; 26(8):400-1.
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  135. Klerman EB, Adler GK, Jin M, Maliszewski AM, Brown EN. A statistical model of diurnal variation in human growth hormone. Am J Physiol Endocrinol Metab. 2003 Nov; 285(5):E1118-26.
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  136. Wirth S, Yanike M, Frank LM, Smith AC, Brown EN, Suzuki WA. Single neurons in the monkey hippocampus and learning of new associations. Science. 2003 Jun 6; 300(5625):1578-81.
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  137. Smith AC, Brown EN. Estimating a state-space model from point process observations. Neural Comput. 2003 May; 15(5):965-91.
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  138. Nguyen DP, Frank LM, Brown EN. An application of reversible-jump Markov chain Monte Carlo to spike classification of multi-unit extracellular recordings. Network. 2003 Feb; 14(1):61-82.
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  139. Bonmassar G, Purdon PL, Jääskeläinen IP, Chiappa K, Solo V, Brown EN, Belliveau JW. Motion and ballistocardiogram artifact removal for interleaved recording of EEG and EPs during MRI. Neuroimage. 2002 Aug; 16(4):1127-41.
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  140. Frank LM, Eden UT, Solo V, Wilson MA, Brown EN. Contrasting patterns of receptive field plasticity in the hippocampus and the entorhinal cortex: an adaptive filtering approach. J Neurosci. 2002 May 1; 22(9):3817-30.
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  141. Brown EN, Barbieri R, Ventura V, Kass RE, Frank LM. The time-rescaling theorem and its application to neural spike train data analysis. Neural Comput. 2002 Feb; 14(2):325-46.
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  142. Brown EN, Nguyen DP, Frank LM, Wilson MA, Solo V. An analysis of neural receptive field plasticity by point process adaptive filtering. Proc Natl Acad Sci U S A. 2001 Oct 9; 98(21):12261-6.
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