 Gregory A. Petsko, PH.D.
| Title | Lecturer on Neurology |
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| Institution | Brigham and Women's Hospital |
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| Department | Neurology |
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| Address | Brandeis University
Rosenstiel Basic Sciences Medical Research Center
Waltham MA 02254
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 Bibliographic
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications.
Faculty can login to make corrections and additions.
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Liu CF, Liu D, Momb J, Thomas PW, Lajoie A, Petsko GA, Fast W, Ringe D. A Phenylalanine Clamp Controls Substrate Specificity in the Quorum-Quenching Metallo-?-lactonase from Bacillus thuringiensis. Biochemistry. 2013 Mar 5; 52(9):1603-10.
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Ringe D, Petsko GA. Behind the movement. Cell. 2012 Sep 14; 150(6):1093-5.
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Petsko GA. Mending walls. BMC Biol. 2012; 10:41.
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Davies CW, Chaney J, Korbel G, Ringe D, Petsko GA, Ploegh H, Das C. The co-crystal structure of ubiquitin carboxy-terminal hydrolase L1 (UCHL1) with a tripeptide fluoromethyl ketone (Z-VAE(OMe)-FMK). Bioorg Med Chem Lett. 2012 Jun 15; 22(12):3900-4.
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Petsko GA. A case of the flu. Genome Biol. 2012; 13(2):146.
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Petsko GA. The dog particle. Genome Biol. 2012; 13(1):142.
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Petsko GA. Apocalypse now? Genome Biol. 2012; 13(3):151.
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Petsko GA. Economies of scale. Genome Biol. 2012; 13(4):154.
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Bharadwaj PR, Verdile G, Barr RK, Gupta V, Steele JW, Lachenmayer ML, Yue Z, Ehrlich ME, Petsko G, Ju S, Ringe D, Sankovich SE, Caine JM, Macreadie IG, Gandy S, Martins RN. Latrepirdine (Dimebon™) Enhances Autophagy and Reduces Intracellular GFP-Aß42 Levels in Yeast. J Alzheimers Dis. 2012 Jan 1; 32(4):949-67.
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Petsko GA. Goodbye, Columbus. Genome Biol. 2012; 13(5):155.
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Auclair JR, Somasundaran M, Green KM, Evans JE, Schiffer CA, Ringe D, Petsko GA, Agar JN. Mass spectrometry tools for analysis of intermolecular interactions. Methods Mol Biol. 2012; 896:387-98.
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Petsko GA. The columnist manifesto. Genome Biol. 2011; 12(12):136.
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Petsko GA, Yates JR. Analyzing molecular interactions. Curr Protoc Bioinformatics. 2011 Dec; Chapter 8:Unit 8.1..
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Petsko GA. Dominoes. Genome Biol. 2011; 12(11):134.
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Petsko GA. Bailing out. Genome Biol. 2011; 12(10):131.
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Wang W, Perovic I, Chittuluru J, Kaganovich A, Nguyen LT, Liao J, Auclair JR, Johnson D, Landeru A, Simorellis AK, Ju S, Cookson MR, Asturias FJ, Agar JN, Webb BN, Kang C, Ringe D, Petsko GA, Pochapsky TC, Hoang QQ. A soluble a-synuclein construct forms a dynamic tetramer. Proc Natl Acad Sci U S A. 2011 Oct 25; 108(43):17797-802.
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Bosco DA, LaVoie MJ, Petsko GA, Ringe D. Proteostasis and movement disorders: Parkinson's disease and amyotrophic lateral sclerosis. Cold Spring Harb Perspect Biol. 2011 Oct; 3(10):a007500.
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Petsko GA. The one new journal we might actually need. Genome Biol. 2011; 12(9):129.
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Petsko GA. Nothing to do and all day to do it in. Genome Biol. 2011; 12(8):126.
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Petsko GA. Herding cats. Sci Transl Med. 2011 Aug 24; 3(97):97cm24.
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Petsko GA. Food of the dogs. Genome Biol. 2011; 12(7):122.
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Petsko GA. Risky business. Genome Biol. 2011; 12(6):119.
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Petsko GA. In praise of model organisms. Genome Biol. 2011; 12(5):115.
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Brodkin HR, Novak WR, Milne AC, D'Aquino JA, Karabacak NM, Goldberg IG, Agar JN, Payne MS, Petsko GA, Ondrechen MJ, Ringe D. Evidence of the participation of remote residues in the catalytic activity of Co-type nitrile hydratase from Pseudomonas putida. Biochemistry. 2011 Jun 7; 50(22):4923-35.
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Petsko GA. The blue marble. Genome Biol. 2011; 12(4):112.
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Lazar LM, Fisher SZ, Moulin AG, Kovalevsky A, Novak WR, Langan P, Petsko GA, Ringe D. Time-of-flight neutron diffraction study of bovine ?-chymotrypsin at the Protein Crystallography Station. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2011 May 1; 67(Pt 5):587-90.
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Ju S, Tardiff DF, Han H, Divya K, Zhong Q, Maquat LE, Bosco DA, Hayward LJ, Brown RH, Lindquist S, Ringe D, Petsko GA. A yeast model of FUS/TLS-dependent cytotoxicity. PLoS Biol. 2011 Apr; 9(4):e1001052.
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Petsko GA. The walking dead. Genome Biol. 2011; 12(3):108.
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Petsko GA. There is a sanity clause. Genome Biol. 2011; 12(2):105.
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Petsko GA. Preserving some sanity. Genome Biol. 2011; 12(1):102.
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Petsko GA. The long and the short of it. Genome Biol. 2010; 11(12):145.
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Petsko G. Save university arts from the bean counters. Nature. 2010 Dec 23; 468(7327):1003.
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Petsko GA. Every dog has his day in court. Genome Biol. 2010; 11(11):139.
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Auclair JR, Boggio KJ, Petsko GA, Ringe D, Agar JN. Strategies for stabilizing superoxide dismutase (SOD1), the protein destabilized in the most common form of familial amyotrophic lateral sclerosis. Proc Natl Acad Sci U S A. 2010 Dec 14; 107(50):21394-9.
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Petsko GA. A Faustian bargain. Genome Biol. 2010; 11(10):138.
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Petsko GA. Shadows on the wall. Genome Biol. 2010; 11(9):136.
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Lewandowski NM, Ju S, Verbitsky M, Ross B, Geddie ML, Rockenstein E, Adame A, Muhammad A, Vonsattel JP, Ringe D, Cote L, Lindquist S, Masliah E, Petsko GA, Marder K, Clark LN, Small SA. Polyamine pathway contributes to the pathogenesis of Parkinson disease. Proc Natl Acad Sci U S A. 2010 Sep 28; 107(39):16970-5.
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Petsko GA. The past is a foreign country. Genome Biol. 2010; 11(8):131.
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Petsko GA. Hand-made biology. Genome Biol. 2010; 11(6):124.
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Petsko GA. When failure should be the option. BMC Biol. 2010; 8:61.
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Gleick PH, Adams RM, Amasino RM, Anders E, Anderson DJ, Anderson WW, Anselin LE, Arroyo MK, Asfaw B, Ayala FJ, Bax A, Bebbington AJ, Bell G, Bennett MV, Bennetzen JL, Berenbaum MR, Berlin OB, Bjorkman PJ, Blackburn E, Blamont JE, Botchan MR, Boyer JS, Boyle EA, Branton D, Briggs SP, Briggs WR, Brill WJ, Britten RJ, Broecker WS, Brown JH, Brown PO, Brunger AT, Cairns J, Canfield DE, Carpenter SR, Carrington JC, Cashmore AR, Castilla JC, Cazenave A, Chapin FS, Ciechanover AJ, Clapham DE, Clark WC, Clayton RN, Coe MD, Conwell EM, Cowling EB, Cowling RM, Cox CS, Croteau RB, Crothers DM, Crutzen PJ, Daily GC, Dalrymple GB, Dangl JL, Darst SA, Davies DR, Davis MB, De Camilli PV, Dean C, DeFries RS, Deisenhofer J, Delmer DP, DeLong EF, DeRosier DJ, Diener TO, Dirzo R, Dixon JE, Donoghue MJ, Doolittle RF, Dunne T, Ehrlich PR, Eisenstadt SN, Eisner T, Emanuel KA, Englander SW, Ernst WG, Falkowski PG, Feher G, Ferejohn JA, Fersht A, Fischer EH, Fischer R, Flannery KV, Frank J, Frey PA, Fridovich I, Frieden C, Futuyma DJ, Gardner WR, Garrett CJ, Gilbert W, Goldberg RB, Goodenough WH, Goodman CS, Goodman M, Greengard P, Hake S, Hammel G, Hanson S, Harrison SC, Hart SR, Hartl DL, Haselkorn R, Hawkes K, Hayes JM, Hille B, Hökfelt T, House JS, Hout M, Hunten DM, Izquierdo IA, Jagendorf AT, Janzen DH, Jeanloz R, Jencks CS, Jury WA, Kaback HR, Kailath T, Kay P, Kay SA, Kennedy D, Kerr A, Kessler RC, Khush GS, Kieffer SW, Kirch PV, Kirk K, Kivelson MG, Klinman JP, Klug A, Knopoff L, Kornberg H, Kutzbach JE, Lagarias JC, Lambeck K, Landy A, Langmuir CH, Larkins BA, Le Pichon XT, Lenski RE, Leopold EB, Levin SA, Levitt M, Likens GE, Lippincott-Schwartz J, Lorand L, Lovejoy CO, Lynch M, Mabogunje AL, Malone TF, Manabe S, Marcus J, Massey DS, McWilliams JC, Medina E, Melosh HJ, Meltzer DJ, Michener CD, Miles EL, Mooney HA, Moore PB, Morel FM, Mosley-Thompson ES, Moss B, Munk WH, Myers N, Nair GB, Nathans J, Nester EW, Nicoll RA, Novick RP, O'Connell JF, Olsen PE, Opdyke ND, Oster GF, Ostrom E, Pace NR, Paine RT, Palmiter RD, Pedlosky J, Petsko GA, Pettengill GH, Philander SG, Piperno DR, Pollard TD, Price PB, Reichard PA, Reskin BF, Ricklefs RE, Rivest RL, Roberts JD, Romney AK, Rossmann MG, Russell DW, Rutter WJ, Sabloff JA, Sagdeev RZ, Sahlins MD, Salmond A, Sanes JR, Schekman R, Schellnhuber J, Schindler DW, Schmitt J, Schneider SH, Schramm VL, Sederoff RR, Shatz CJ, Sherman F, Sidman RL, Sieh K, Simons EL, Singer BH, Singer MF, Skyrms B, Sleep NH, Smith BD, Snyder SH, Sokal RR, Spencer CS, Steitz TA, Strier KB, Südhof TC, Taylor SS, Terborgh J, Thomas DH, Thompson LG, Tjian RT, Turner MG, Uyeda S, Valentine JW, Valentine JS, Van Etten JL, van Holde KE, Vaughan M, Verba S, von Hippel PH, Wake DB, Walker A, Walker JE, Watson EB, Watson PJ, Weigel D, Wessler SR, West-Eberhard MJ, White TD, Wilson WJ, Wolfenden RV, Wood JA, Woodwell GM, Wright HE, Wu C, Wunsch C, Zoback ML. Climate change and the integrity of science. Science. 2010 May 7; 328(5979):689-90.
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Petsko GA. And they said it wouldn't last... Genome Biol. 2010; 11(5):121.
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Petsko GA. The devil's in the details. Genome Biol. 2010; 11(4):117.
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Petsko GA. No stone unturned. Genome Biol. 2010; 11(3):112.
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Petsko GA. Lost in translation. Genome Biol. 2010; 11(2):107.
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Petsko GA. Rising in the East. Genome Biol. 2010; 11(1):102.
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Brandt GS, Kneen MM, Petsko GA, Ringe D, McLeish MJ. Active-site engineering of benzaldehyde lyase shows that a point mutation can confer both new reactivity and susceptibility to mechanism-based inhibition. J Am Chem Soc. 2010 Jan 20; 132(2):438-9.
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Petsko GA. When the pie is too small. Genome Biol. 2010; 11(7):127.
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Petsko GA. A harsh climate. Genome Biol. 2009; 10(12):115.
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Petsko GA. Big science, little science. EMBO Rep. 2009 Dec; 10(12):1282.
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Petsko GA. Advice and dissent. Genome Biol. 2009; 10(11):113.
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Petsko GA. The dog days of autumn. Genome Biol. 2009; 10(10):112.
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Ringe D, Petsko GA. What are pharmacological chaperones and why are they interesting? J Biol. 2009; 8(9):80.
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Petsko GA. Crystallographic cryoenzymology and the legacy of Tony Fink. Curr Protein Pept Sci. 2009 Oct; 10(5):416-23.
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Petsko GA. An issue to remember. Genome Biol. 2009; 10(9):111.
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Petsko GA. Wimps? What wimps? Genome Biol. 2009; 10(7):109.
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Sigala PA, Caaveiro JM, Ringe D, Petsko GA, Herschlag D. Hydrogen bond coupling in the ketosteroid isomerase active site. Biochemistry. 2009 Jul 28; 48(29):6932-9.
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Petsko GA. What my genome told me--and what it didn't. Genome Biol. 2009; 10(6):108.
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Landon MR, Lieberman RL, Hoang QQ, Ju S, Caaveiro JM, Orwig SD, Kozakov D, Brenke R, Chuang GY, Beglov D, Vajda S, Petsko GA, Ringe D. Detection of ligand binding hot spots on protein surfaces via fragment-based methods: application to DJ-1 and glucocerebrosidase. J Comput Aided Mol Des. 2009 Aug; 23(8):491-500.
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Lieberman RL, D'aquino JA, Ringe D, Petsko GA. Effects of pH and iminosugar pharmacological chaperones on lysosomal glycosidase structure and stability. Biochemistry. 2009 Jun 9; 48(22):4816-27.
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Petsko GA. Render unto Darwin. Genome Biol. 2009; 10(5):106.
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Petsko GA. Guilt by association. Genome Biol. 2009; 10(4):104.
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Brandt GS, Kneen MM, Chakraborty S, Baykal AT, Nemeria N, Yep A, Ruby DI, Petsko GA, Kenyon GL, McLeish MJ, Jordan F, Ringe D. Snapshot of a reaction intermediate: analysis of benzoylformate decarboxylase in complex with a benzoylphosphonate inhibitor. Biochemistry. 2009 Apr 21; 48(15):3247-57.
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Petsko GA. The greatest book you never read. EMBO Rep. 2009 Apr; 10(4):298.
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Petsko GA. Too big to succeed? Genome Biol. 2009; 10(3):103.
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Novak WR, Moulin AG, Blakeley MP, Schlichting I, Petsko GA, Ringe D. A preliminary neutron diffraction study of gamma-chymotrypsin. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2009 Mar 1; 65(Pt 3):317-20.
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Chakraborty S, Nemeria NS, Balakrishnan A, Brandt GS, Kneen MM, Yep A, McLeish MJ, Kenyon GL, Petsko GA, Ringe D, Jordan F. Detection and time course of formation of major thiamin diphosphate-bound covalent intermediates derived from a chromophoric substrate analogue on benzoylformate decarboxylase. Biochemistry. 2009 Feb 10; 48(5):981-94.
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Petsko GA. Life is a Ponzi scheme. Genome Biol. 2009; 10(1):101.
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Petsko GA. The wisdom, and madness, of crowds. Genome Biol. 2008; 9(11):112.
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Petsko GA. Meta-morphosis. Genome Biol. 2008; 9(10):111.
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Petsko GA. When bubbles burst. Genome Biol. 2008; 9(9):110.
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Sigala PA, Kraut DA, Caaveiro JM, Pybus B, Ruben EA, Ringe D, Petsko GA, Herschlag D. Testing geometrical discrimination within an enzyme active site: constrained hydrogen bonding in the ketosteroid isomerase oxyanion hole. J Am Chem Soc. 2008 Oct 15; 130(41):13696-708.
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Petsko GA. Biodefense versus bioterrorism. Genome Biol. 2008; 9(8):108.
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Petsko GA. Having an impact (factor). Genome Biol. 2008; 9(7):107.
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Momb J, Wang C, Liu D, Thomas PW, Petsko GA, Guo H, Ringe D, Fast W. Mechanism of the quorum-quenching lactonase (AiiA) from Bacillus thuringiensis. 2. Substrate modeling and active site mutations. Biochemistry. 2008 Jul 22; 47(29):7715-25.
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Liu D, Momb J, Thomas PW, Moulin A, Petsko GA, Fast W, Ringe D. Mechanism of the quorum-quenching lactonase (AiiA) from Bacillus thuringiensis. 1. Product-bound structures. Biochemistry. 2008 Jul 22; 47(29):7706-14.
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Ataie NJ, Hoang QQ, Zahniser MP, Tu Y, Milne A, Petsko GA, Ringe D. Zinc coordination geometry and ligand binding affinity: the structural and kinetic analysis of the second-shell serine 228 residue and the methionine 180 residue of the aminopeptidase from Vibrio proteolyticus. Biochemistry. 2008 Jul 22; 47(29):7673-83.
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Petsko GA. It is alive. Genome Biol. 2008; 9(6):106.
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Brandt GS, Nemeria N, Chakraborty S, McLeish MJ, Yep A, Kenyon GL, Petsko GA, Jordan F, Ringe D. Probing the active center of benzaldehyde lyase with substitutions and the pseudosubstrate analogue benzoylphosphonic acid methyl ester. Biochemistry. 2008 Jul 22; 47(29):7734-43.
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Ringe D, Petsko GA. Biochemistry. How enzymes work. Science. 2008 Jun 13; 320(5882):1428-9.
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Petsko GA. The new Manichaeans. Genome Biol. 2008; 9(5):105.
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Petsko GA. Not debatable. Genome Biol. 2008; 9(4):104.
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Petsko GA. The right to be wrong. Genome Biol. 2008; 9(2):102.
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Petsko GA. The story they missed. Genome Biol. 2008; 9(1):101.
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Petsko GA. A seat at the table. Genome Biol. 2008; 9(12):113.
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Henzler-Wildman KA, Thai V, Lei M, Ott M, Wolf-Watz M, Fenn T, Pozharski E, Wilson MA, Petsko GA, Karplus M, Hübner CG, Kern D. Intrinsic motions along an enzymatic reaction trajectory. Nature. 2007 Dec 6; 450(7171):838-44.
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Liu D, Thomas PW, Momb J, Hoang QQ, Petsko GA, Ringe D, Fast W. Structure and specificity of a quorum-quenching lactonase (AiiB) from Agrobacterium tumefaciens. Biochemistry. 2007 Oct 23; 46(42):11789-99.
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Liu D, Pozharski E, Lepore BW, Fu M, Silverman RB, Petsko GA, Ringe D. Inactivation of Escherichia coli L-aspartate aminotransferase by (S)-4-amino-4,5-dihydro-2-thiophenecarboxylic acid reveals "a tale of two mechanisms". Biochemistry. 2007 Sep 18; 46(37):10517-27.
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Munih P, Moulin A, Stamper CC, Bennett B, Ringe D, Petsko GA, Holz RC. X-ray crystallographic characterization of the Co(II)-substituted Tris-bound form of the aminopeptidase from Aeromonas proteolytica. J Inorg Biochem. 2007 Aug; 101(8):1099-107.
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Petsko GA. Jumping the shark. Genome Biol. 2007; 8(1):101.
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Petsko GA. They fought the law and the law won. Genome Biol. 2007; 8(10):111.
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Petsko GA. What if Watson had said "Apes evolved from man"? Genome Biol. 2007; 8(11):113.
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Petsko GA. And the second shall be first. Genome Biol. 2007; 8(2):103.
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Petsko GA. It can't happen here--can it? Genome Biol. 2007; 8(4):105.
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Petsko GA. A day in the life of a genome biologist in the not-too-distant future. Genome Biol. 2007; 8(3):104.
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Petsko GA. An idea whose time has gone. Genome Biol. 2007; 8(6):107.
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Petsko GA. Medicine man. Genome Biol. 2007; 8(12):114.
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Petsko GA. My worries are no longer behind me. Genome Biol. 2007; 8(8):109.
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Petsko GA. Strange days. Genome Biol. 2007; 8(9):110.
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Lieberman RL, Wustman BA, Huertas P, Powe AC, Pine CW, Khanna R, Schlossmacher MG, Ringe D, Petsko GA. Structure of acid beta-glucosidase with pharmacological chaperone provides insight into Gaucher disease. Nat Chem Biol. 2007 Feb; 3(2):101-7.
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Ding X, Rasmussen BF, Petsko GA, Ringe D. Direct crystallographic observation of an acyl-enzyme intermediate in the elastase-catalyzed hydrolysis of a peptidyl ester substrate: Exploiting the "glass transition" in protein dynamics. Bioorg Chem. 2006 Dec; 34(6):410-23.
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Petsko GA. Transformation. Genome Biol. 2006; 7(10):117.
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Petsko GA. An introduction to modeling structure from sequence. Curr Protoc Bioinformatics. 2006 Oct; Chapter 5:Unit 5.1.
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Petsko GA. The next epidemic. Genome Biol. 2006; 7(5):108.
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Desmarais W, Bienvenue DL, Bzymek KP, Petsko GA, Ringe D, Holz RC. The high-resolution structures of the neutral and the low pH crystals of aminopeptidase from Aeromonas proteolytica. J Biol Inorg Chem. 2006 Jun; 11(4):398-408.
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Petsko GA. The system is broken. Genome Biol. 2006; 7(3):105.
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Kraut DA, Sigala PA, Pybus B, Liu CW, Ringe D, Petsko GA, Herschlag D. Testing electrostatic complementarity in enzyme catalysis: hydrogen bonding in the ketosteroid isomerase oxyanion hole. PLoS Biol. 2006 Apr; 4(4):e99.
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Das C, Hoang QQ, Kreinbring CA, Luchansky SJ, Meray RK, Ray SS, Lansbury PT, Ringe D, Petsko GA. Structural basis for conformational plasticity of the Parkinson's disease-associated ubiquitin hydrolase UCH-L1. Proc Natl Acad Sci U S A. 2006 Mar 21; 103(12):4675-80.
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Petsko GA. Sweden has the right idea. Genome Biol. 2006; 7(2):103.
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Petsko GA. The highs and lows of scientific conferences. Nat Rev Mol Cell Biol. 2006 Mar; 7(3):231-4.
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Mattos C, Bellamacina CR, Peisach E, Pereira A, Vitkup D, Petsko GA, Ringe D. Multiple solvent crystal structures: probing binding sites, plasticity and hydration. J Mol Biol. 2006 Apr 14; 357(5):1471-82.
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Petsko GA. Foxes and hounds. Genome Biol. 2005; 6(13):124.
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Petsko GA. A model worth considering? Genome Biol. 2006; 7(12):121.
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Petsko GA. Do the math. Genome Biol. 2006; 7(11):119.
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Petsko GA. Senior moments. Genome Biol. 2006; 7(8):113.
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Petsko GA. Instructions for repair. Genome Biol. 2006; 7(4):106.
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Petsko GA. Facts and figures. Genome Biol. 2006; 7(7):111.
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Petsko GA. The ninth wave. Genome Biol. 2006; 7(6):109.
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Zhou W, Zhu M, Wilson MA, Petsko GA, Fink AL. The oxidation state of DJ-1 regulates its chaperone activity toward alpha-synuclein. J Mol Biol. 2006 Mar 3; 356(4):1036-48.
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Petsko GA. H5N1. Genome Biol. 2005; 6(11):121.
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Petsko GA. Half right. Genome Biol. 2005; 6(10):120.
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Bzymek KP, Moulin A, Swierczek SI, Ringe D, Petsko GA, Bennett B, Holz RC. Kinetic, spectroscopic, and X-ray crystallographic characterization of the functional E151H aminopeptidase from Aeromonas proteolytica. Biochemistry. 2005 Sep 13; 44(36):12030-40.
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Wilson MA, Ringe D, Petsko GA. The atomic resolution crystal structure of the YajL (ThiJ) protein from Escherichia coli: a close prokaryotic homologue of the Parkinsonism-associated protein DJ-1. J Mol Biol. 2005 Oct 28; 353(3):678-91.
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Petsko GA. Trinity. Genome Biol. 2005; 6(9):118.
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Liu D, Lepore BW, Petsko GA, Thomas PW, Stone EM, Fast W, Ringe D. Three-dimensional structure of the quorum-quenching N-acyl homoserine lactone hydrolase from Bacillus thuringiensis. Proc Natl Acad Sci U S A. 2005 Aug 16; 102(33):11882-7.
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Petsko GA. Superman's eyes. Biochim Biophys Acta. 2005 Aug 5; 1724(3):225-6.
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Petsko GA. The life aquatic. Genome Biol. 2005; 6(8):116.
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Petsko GA. Eighty years ago. Genome Biol. 2005; 6(7):114.
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Petsko GA. How may you help me? Genome Biol. 2005; 6(6):111.
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Petsko GA. A matter of life and death. Genome Biol. 2005; 6(5):109.
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Pozharski E, Moulin A, Hewagama A, Shanafelt AB, Petsko GA, Ringe D. Diversity in hapten recognition: structural study of an anti-cocaine antibody M82G2. J Mol Biol. 2005 Jun 10; 349(3):570-82.
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Beilina A, Van Der Brug M, Ahmad R, Kesavapany S, Miller DW, Petsko GA, Cookson MR. Mutations in PTEN-induced putative kinase 1 associated with recessive parkinsonism have differential effects on protein stability. Proc Natl Acad Sci U S A. 2005 Apr 19; 102(16):5703-8.
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Petsko GA. Who owns the data? Genome Biol. 2005; 6(4):107.
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Petsko GA. Feet in mouth disease. Genome Biol. 2005; 6(3):105.
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Petsko GA. Tsunami. Genome Biol. 2005; 6(2):104.
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Petsko GA. Color blind. Genome Biol. 2004; 5(12):119.
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Petsko GA. The emperor's new shibboleth. Genome Biol. 2004; 5(11):118.
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Petsko GA. Twilight of a hero. Genome Biol. 2004; 5(10):116.
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Petsko GA. Fame is a bubble, but not for some. Genome Biol. 2004; 5(9):114.
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Yang J, Wang Y, Woolridge EM, Arora V, Petsko GA, Kozarich JW, Ringe D. Crystal structure of 3-carboxy-cis,cis-muconate lactonizing enzyme from Pseudomonas putida, a fumarase class II type cycloisomerase: enzyme evolution in parallel pathways. Biochemistry. 2004 Aug 17; 43(32):10424-34.
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Stamper CC, Bienvenue DL, Bennett B, Ringe D, Petsko GA, Holz RC. Spectroscopic and X-ray crystallographic characterization of bestatin bound to the aminopeptidase from Aeromonas (Vibrio) proteolytica. Biochemistry. 2004 Aug 3; 43(30):9620-8.
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Petsko GA. A drop in the bucket. Genome Biol. 2004; 5(8):112.
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Canet-Avilés RM, Wilson MA, Miller DW, Ahmad R, McLendon C, Bandyopadhyay S, Baptista MJ, Ringe D, Petsko GA, Cookson MR. The Parkinson's disease protein DJ-1 is neuroprotective due to cysteine-sulfinic acid-driven mitochondrial localization. Proc Natl Acad Sci U S A. 2004 Jun 15; 101(24):9103-8.
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Fenn TD, Ringe D, Petsko GA. Xylose isomerase in substrate and inhibitor michaelis states: atomic resolution studies of a metal-mediated hydride shift. Biochemistry. 2004 Jun 1; 43(21):6464-74.
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Gray JV, Petsko GA, Johnston GC, Ringe D, Singer RA, Werner-Washburne M. "Sleeping beauty": quiescence in Saccharomyces cerevisiae. Microbiol Mol Biol Rev. 2004 Jun; 68(2):187-206.
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Petsko GA. Pharmacogenomics arrives. Genome Biol. 2004; 5(6):108.
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Petsko GA. The ascent of man? Genome Biol. 2004; 5(5):106.
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Petsko GA. Doctor Dunsel. Genome Biol. 2004; 5(4):104.
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Pozharski E, Wilson MA, Hewagama A, Shanafelt AB, Petsko G, Ringe D. Anchoring a cationic ligand: the structure of the Fab fragment of the anti-morphine antibody 9B1 and its complex with morphine. J Mol Biol. 2004 Mar 26; 337(3):691-7.
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Vogan EM, Bellamacina C, He X, Liu HW, Ringe D, Petsko GA. Crystal structure at 1.8 A resolution of CDP-D-glucose 4,6-dehydratase from Yersinia pseudotuberculosis. Biochemistry. 2004 Mar 23; 43(11):3057-67.
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Holyoak T, Kettner CA, Petsko GA, Fuller RS, Ringe D. Structural basis for differences in substrate selectivity in Kex2 and furin protein convertases. Biochemistry. 2004 Mar 9; 43(9):2412-21.
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Petsko GA. Good chemistry. Genome Biol. 2004; 5(3):103.
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Petsko GA. Bad chemistry. Genome Biol. 2004; 5(2):102.
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Wilson MA, St Amour CV, Collins JL, Ringe D, Petsko GA. The 1.8-A resolution crystal structure of YDR533Cp from Saccharomyces cerevisiae: a member of the DJ-1/ThiJ/PfpI superfamily. Proc Natl Acad Sci U S A. 2004 Feb 10; 101(6):1531-6.
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Petsko GA. Live and let diet. Genome Biol. 2003; 5(1):101.
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Holyoak T, Fenn TD, Wilson MA, Moulin AG, Ringe D, Petsko GA. Malonate: a versatile cryoprotectant and stabilizing solution for salt-grown macromolecular crystals. Acta Crystallogr D Biol Crystallogr. 2003 Dec; 59(Pt 12):2356-8.
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Petsko GA. For the good of the state. Genome Biol. 2003; 4(12):121.
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Petsko GA. Sleeping dogs. Genome Biol. 2003; 4(11):120.
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Petsko GA. The usual suspects. Genome Biol. 2003; 4(10):118.
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Ringe D, Petsko GA. The 'glass transition' in protein dynamics: what it is, why it occurs, and how to exploit it. Biophys Chem. 2003 Sep; 105(2-3):667-80.
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Petsko GA. The road worrier. Genome Biol. 2003; 4(9):116.
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Petsko GA. Galileo's stepchildren. Genome Biol. 2003; 4(8):114.
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Wilson MA, Collins JL, Hod Y, Ringe D, Petsko GA. The 1.1-A resolution crystal structure of DJ-1, the protein mutated in autosomal recessive early onset Parkinson's disease. Proc Natl Acad Sci U S A. 2003 Aug 5; 100(16):9256-61.
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Petsko GA. A new recruit for the army of the men of death. Genome Biol. 2003; 4(7):113.
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Holyoak T, Wilson MA, Fenn TD, Kettner CA, Petsko GA, Fuller RS, Ringe D. 2.4 A resolution crystal structure of the prototypical hormone-processing protease Kex2 in complex with an Ala-Lys-Arg boronic acid inhibitor. Biochemistry. 2003 Jun 10; 42(22):6709-18.
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Petsko GA. Ira. Genome Biol. 2003; 4(6):112.
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Petsko GA. Analyzing molecular interactions. Curr Protoc Bioinformatics. 2003 May; Chapter 8:Unit8.1.
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Petsko GA. War and peace. Genome Biol. 2003; 4(5):110.
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Beebe JA, Arabshahi A, Clifton JG, Ringe D, Petsko GA, Frey PA. Galactose mutarotase: pH dependence of enzymatic mutarotation. Biochemistry. 2003 Apr 22; 42(15):4414-20.
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Petsko GA. Judgement call. Genome Biol. 2003; 4(4):108.
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Petsko GA. Still no flying cars. Genome Biol. 2003; 4(3):106.
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Gan L, Seyedsayamdost MR, Shuto S, Matsuda A, Petsko GA, Hedstrom L. The immunosuppressive agent mizoribine monophosphate forms a transition state analogue complex with inosine monophosphate dehydrogenase. Biochemistry. 2003 Feb 4; 42(4):857-63.
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Petsko GA. Funky, not junky. Genome Biol. 2003; 4(2):104.
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Petsko GA. Everything I need to know about genomics, I learned from Yogi Berra. Genome Biol. 2003; 4(1):102.
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Gan L, Petsko GA, Hedstrom L. Crystal structure of a ternary complex of Tritrichomonas foetus inosine 5'-monophosphate dehydrogenase: NAD+ orients the active site loop for catalysis. Biochemistry. 2002 Nov 5; 41(44):13309-17.
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Petsko GA. The guards themselves. Genome Biol. 2002 Oct 25; 3(11):comment1015.
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Kenyon GL, DeMarini DM, Fuchs E, Galas DJ, Kirsch JF, Leyh TS, Moos WH, Petsko GA, Ringe D, Rubin GM, Sheahan LC. Defining the mandate of proteomics in the post-genomics era: workshop report. Mol Cell Proteomics. 2002 Oct; 1(10):763-80.
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Petsko GA. An Asilomar moment. Genome Biol. 2002 Sep 25; 3(10):COMMENT1014.
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Trotter EW, Kao CM, Berenfeld L, Botstein D, Petsko GA, Gray JV. Misfolded proteins are competent to mediate a subset of the responses to heat shock in Saccharomyces cerevisiae. J Biol Chem. 2002 Nov 22; 277(47):44817-25.
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Petsko GA. Fish tale. Genome Biol. 2002 Aug 27; 3(9):comment1012.
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Desmarais WT, Bienvenue DL, Bzymek KP, Holz RC, Petsko GA, Ringe D. The 1.20 A resolution crystal structure of the aminopeptidase from Aeromonas proteolytica complexed with tris: a tale of buffer inhibition. Structure. 2002 Aug; 10(8):1063-72.
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Petsko GA. No place like Ome. Genome Biol. 2002 Jun 26; 3(7):COMMENT1010.
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Petsko GA. Our own petards. Genome Biol. 2002; 3(6):COMMENT1009.
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Petsko GA. Grain of truth. Genome Biol. 2002; 3(5):comment1007.
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Petsko GA. What's in a name? Genome Biol. 2002; 3(4):COMMENT1005.
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Vitkup D, Ringe D, Karplus M, Petsko GA. Why protein R-factors are so large: a self-consistent analysis. Proteins. 2002 Mar 1; 46(4):345-54.
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Bahnson BJ, Anderson VE, Petsko GA. Structural mechanism of enoyl-CoA hydratase: three atoms from a single water are added in either an E1cb stepwise or concerted fashion. Biochemistry. 2002 Feb 26; 41(8):2621-9.
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Petsko GA. The father of us all. Genome Biol. 2002; 3(3):COMMENT1004.
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Vogan EM, Bellamacina CR, He X, Foxman BM, Ringe D, Liu HW, Petsko GA. Purification, crystallization and molecular symmetry of CDP-D-glucose 4,6-dehydratase from Yersinia pseudotuberculosis. Acta Crystallogr D Biol Crystallogr. 2002 Feb; 58(Pt 2):370-3.
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Petsko GA. A christmas carol. Genome Biol. 2002; 3(1):COMMENT1001.
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Hadfield A, Shammas C, Kryger G, Ringe D, Petsko GA, Ouyang J, Viola RE. Active site analysis of the potential antimicrobial target aspartate semialdehyde dehydrogenase. Biochemistry. 2001 Dec 4; 40(48):14475-83.
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Petsko GA. A piece of the action. Genome Biol. 2001; 2(12):COMMENT1014.
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Petsko GA. Winter, plague and pestilence. Genome Biol. 2001; 2(11):COMMENT1013.
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Petsko GA. Design by necessity. Genome Biol. 2001; 2(8):COMMENT1010.
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Petsko GA. Model behavior. Genome Biol. 2001; 2(7):COMMENT1009.
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Trotter EW, Berenfeld L, Krause SA, Petsko GA, Gray JV. Protein misfolding and temperature up-shift cause G1 arrest via a common mechanism dependent on heat shock factor in Saccharomycescerevisiae. Proc Natl Acad Sci U S A. 2001 Jun 19; 98(13):7313-8.
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Stamper C, Bennett B, Edwards T, Holz RC, Ringe D, Petsko G. Inhibition of the aminopeptidase from Aeromonas proteolytica by L-leucinephosphonic acid. Spectroscopic and crystallographic characterization of the transition state of peptide hydrolysis. Biochemistry. 2001 Jun 19; 40(24):7035-46.
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Petsko GA. Location, location, location. Genome Biol. 2001; 2(6):COMMENT1008.
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Petsko GA. The Rosetta stone. Genome Biol. 2001; 2(5):COMMENT1007.
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Petsko GA. The slide rule and the calculator. Genome Biol. 2001; 2(4):COMMENT1004.
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Petsko GA. Size doesn't matter. Genome Biol. 2001; 2(3):COMMENT1003.
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Petsko GA. Homologuephobia. Genome Biol. 2001; 2(2):COMMENT1002.
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Petsko GA. Structural basis of thermostability in hyperthermophilic proteins, or "there's more than one way to skin a cat". Methods Enzymol. 2001; 334:469-78.
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Petsko GA. Count me out. Genome Biol. 2000; 1(6):COMMENT1006.
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Petsko GA. Seek and ye shall maybe find. Genome Biol. 2000; 1(5):COMMENT1005.
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Heymont J, Berenfeld L, Collins J, Kaganovich A, Maynes B, Moulin A, Ratskovskaya I, Poon PP, Johnston GC, Kamenetsky M, DeSilva J, Sun H, Petsko GA, Engebrecht J. TEP1, the yeast homolog of the human tumor suppressor gene PTEN/MMAC1/TEP1, is linked to the phosphatidylinositol pathway and plays a role in the developmental process of sporulation. Proc Natl Acad Sci U S A. 2000 Nov 7; 97(23):12672-7.
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Petsko GA. Perpetual motion of the worst kind. Genome Biol. 2000; 1(4):COMMENT1004.
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Petsko GA. The dark side. Genome Biol. 2000; 1(3):COMMENT1003.
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Petsko GA. Dog eat dogma. Genome Biol. 2000; 1(2):comment1002.1-1002.2.
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Petsko GA. The grail problem. Genome Biol. 2000; 1(1):COMMENT002.
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McMillan FM, Cahoon M, White A, Hedstrom L, Petsko GA, Ringe D. Crystal structure at 2.4 A resolution of Borrelia burgdorferi inosine 5'-monophosphate dehydrogenase: evidence of a substrate-induced hinged-lid motion by loop 6. Biochemistry. 2000 Apr 18; 39(15):4533-42.
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Schlichting I, Berendzen J, Chu K, Stock AM, Maves SA, Benson DE, Sweet RM, Ringe D, Petsko GA, Sligar SG. The catalytic pathway of cytochrome p450cam at atomic resolution. Science. 2000 Mar 3; 287(5458):1615-22.
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Petsko GA. Enzyme evolution. Design by necessity. Nature. 2000 Feb 10; 403(6770):606-7.
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Jeffery CJ, Bahnson BJ, Chien W, Ringe D, Petsko GA. Crystal structure of rabbit phosphoglucose isomerase, a glycolytic enzyme that moonlights as neuroleukin, autocrine motility factor, and differentiation mediator. Biochemistry. 2000 Feb 8; 39(5):955-64.
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Jeffery CJ, Gloss LM, Petsko GA, Ringe D. The role of residues outside the active site: structural basis for function of C191 mutants of Escherichia coli aspartate aminotransferase. Protein Eng. 2000 Feb; 13(2):105-12.
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Petsko GA, Ringe D. Observation of unstable species in enzyme-catalyzed transformations using protein crystallography. Curr Opin Chem Biol. 2000 Feb; 4(1):89-94.
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Petsko GA. Chemistry and biology. Proc Natl Acad Sci U S A. 2000 Jan 18; 97(2):538-40.
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Vitkup D, Ringe D, Petsko GA, Karplus M. Solvent mobility and the protein 'glass' transition. Nat Struct Biol. 2000 Jan; 7(1):34-8.
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De Paola CC, Bennett B, Holz RC, Ringe D, Petsko GA. 1-Butaneboronic acid binding to Aeromonas proteolytica aminopeptidase: a case of arrested development. Biochemistry. 1999 Jul 13; 38(28):9048-53.
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Johnson LN, Petsko GA. David Phillips and the origin of structural enzymology. Trends Biochem Sci. 1999 Jul; 24(7):287-9.
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Hadfield A, Kryger G, Ouyang J, Petsko GA, Ringe D, Viola R. Structure of aspartate-beta-semialdehyde dehydrogenase from Escherichia coli, a key enzyme in the aspartate family of amino acid biosynthesis. J Mol Biol. 1999 Jun 18; 289(4):991-1002.
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Ringe D, Petsko GA. Quantum enzymology. Tunnel vision. Nature. 1999 Jun 3; 399(6735):417-8.
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Hadfield AT, Petsko G, Lindo P, Singh BR. Preliminary crystallographic studies of a protease resistant botulinum neurotoxin associated protein Hn-33. Acta Crystallogr D Biol Crystallogr. 1999 Jun; 55(Pt 6):1237-9.
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Johnson LN, Petsko GA. David Phillips (1924-99) Nature. 1999 May 6; 399(6731):26.
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Zhang Z, Komives EA, Sugio S, Blacklow SC, Narayana N, Xuong NH, Stock AM, Petsko GA, Ringe D. The role of water in the catalytic efficiency of triosephosphate isomerase. Biochemistry. 1999 Apr 6; 38(14):4389-97.
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Morollo AA, Petsko GA, Ringe D. Structure of a Michaelis complex analogue: propionate binds in the substrate carboxylate site of alanine racemase. Biochemistry. 1999 Mar 16; 38(11):3293-301.
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Hasson MS, Schlichting I, Moulai J, Taylor K, Barrett W, Kenyon GL, Babbitt PC, Gerlt JA, Petsko GA, Ringe D. Evolution of an enzyme active site: the structure of a new crystal form of muconate lactonizing enzyme compared with mandelate racemase and enolase. Proc Natl Acad Sci U S A. 1998 Sep 1; 95(18):10396-401.
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Sugio S, Kashima A, Kishimoto K, Peisach D, Petsko GA, Ringe D, Yoshimura T, Esaki N. Crystal structures of L201A mutant of D-amino acid aminotransferase at 2.0 A resolution: implication of the structural role of Leu201 in transamination. Protein Eng. 1998 Aug; 11(8):613-9.
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Hasson MS, Muscate A, McLeish MJ, Polovnikova LS, Gerlt JA, Kenyon GL, Petsko GA, Ringe D. The crystal structure of benzoylformate decarboxylase at 1.6 A resolution: diversity of catalytic residues in thiamin diphosphate-dependent enzymes. Biochemistry. 1998 Jul 14; 37(28):9918-30.
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Jeffery CJ, Barry T, Doonan S, Petsko GA, Ringe D. Crystallization and preliminary X-ray diffraction analysis of aspartate aminotransferase from Saccharomyces cerevisiae. Acta Crystallogr D Biol Crystallogr. 1998 Jul 1; 54(Pt 4):659-61.
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Závodszky P, Kardos J, Petsko GA. Adjustment of conformational flexibility is a key event in the thermal adaptation of proteins. Proc Natl Acad Sci U S A. 1998 Jun 23; 95(13):7406-11.
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Jeffery CJ, Barry T, Doonan S, Petsko GA, Ringe D. Crystal structure of Saccharomyces cerevisiae cytosolic aspartate aminotransferase. Protein Sci. 1998 Jun; 7(6):1380-7.
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Yamakura F, Rardin RL, Petsko GA, Ringe D, Hiraoka BY, Nakayama K, Fujimura T, Taka H, Murayama K. Inactivation and destruction of conserved Trp159 of Fe-superoxide dismutase from Porphyromonas gingivalis by hydrogen peroxide. Eur J Biochem. 1998 Apr 1; 253(1):49-56.
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van Ophem PW, Erickson SD, Martinez del Pozo A, Haller I, Chait BT, Yoshimura T, Soda K, Ringe D, Petsko G, Manning JM. Substrate inhibition of D-amino acid transaminase and protection by salts and by reduced nicotinamide adenine dinucleotide: isolation and initial characterization of a pyridoxo intermediate related to inactivation. Biochemistry. 1998 Mar 3; 37(9):2879-88.
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Wlodawer A, Davies D, Petsko G, Rossmann M, Olson A, Sussman JL. Immediate release of crystallographic data: a proposal. Science. 1998 Jan 16; 279(5349):306-7.
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Harrison DH, Bohren KM, Petsko GA, Ringe D, Gabbay KH. The alrestatin double-decker: binding of two inhibitor molecules to human aldose reductase reveals a new specificity determinant. Biochemistry. 1997 Dec 23; 36(51):16134-40.
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Wallon G, Lovett ST, Magyar C, Svingor A, Szilagyi A, Zàvodszky P, Ringe D, Petsko GA. Sequence and homology model of 3-isopropylmalate dehydrogenase from the psychrotrophic bacterium Vibrio sp. I5 suggest reasons for thermal instability. Protein Eng. 1997 Jun; 10(6):665-72.
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Hasson MS, Schlichting I, McGowen MM, Woolridge EM, Kozarich JW, Petsko GA, Ringe D. Characterization of two crystal forms of 3-carboxy-cis,cis-muconate lactonizing enzyme from Pseudomonas putida. Acta Crystallogr D Biol Crystallogr. 1997 May 1; 53(Pt 3):352-3.
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Wallon G, Kryger G, Lovett ST, Oshima T, Ringe D, Petsko GA. Crystal structures of Escherichia coli and Salmonella typhimurium 3-isopropylmalate dehydrogenase and comparison with their thermophilic counterpart from Thermus thermophilus. J Mol Biol. 1997 Mar 14; 266(5):1016-31.
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Vitkup D, Petsko GA, Karplus M. A comparison between molecular dynamics and X-ray results for dissociated CO in myoglobin. Nat Struct Biol. 1997 Mar; 4(3):202-8.
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Brenner C, Garrison P, Gilmour J, Peisach D, Ringe D, Petsko GA, Lowenstein JM. Crystal structures of HINT demonstrate that histidine triad proteins are GalT-related nucleotide-binding proteins. Nat Struct Biol. 1997 Mar; 4(3):231-8.
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Shaw JP, Petsko GA, Ringe D. Determination of the structure of alanine racemase from Bacillus stearothermophilus at 1.9-A resolution. Biochemistry. 1997 Feb 11; 36(6):1329-42.
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Wallon G, Yamamoto K, Kirino H, Yamagishi A, Lovett ST, Petsko GA, Oshima T. Purification, catalytic properties and thermostability of 3-isopropylmalate dehydrogenase from Escherichia coli. Biochim Biophys Acta. 1997 Jan 4; 1337(1):105-12.
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Komives EA, Lougheed JC, Zhang Z, Sugio S, Narayana N, Xuong NH, Petsko GA, Ringe D. The structural basis for pseudoreversion of the H95N lesion by the secondary S96P mutation in triosephosphate isomerase. Biochemistry. 1996 Dec 3; 35(48):15474-84.
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Jones WM, van Ophem PW, Pospischil MA, Ringe D, Petsko G, Soda K, Manning JM. The ubiquitous cofactor NADH protects against substrate-induced inhibition of a pyridoxal enzyme. Protein Sci. 1996 Dec; 5(12):2545-51.
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Petsko GA. For medicinal purposes. Nature. 1996 Nov 7; 384(6604 Suppl):7-9.
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Petsko GA. Not just your average structures. Nat Struct Biol. 1996 Jul; 3(7):565-6.
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Schafer SL, Barrett WC, Kallarakal AT, Mitra B, Kozarich JW, Gerlt JA, Clifton JG, Petsko GA, Kenyon GL. Mechanism of the reaction catalyzed by mandelate racemase: structure and mechanistic properties of the D270N mutant. Biochemistry. 1996 May 7; 35(18):5662-9.
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Martinez del Pozo A, van Ophem PW, Ringe D, Petsko G, Soda K, Manning JM. Interaction of pyridoxal 5'-phosphate with tryptophan-139 at the subunit interface of dimeric D-amino acid transaminase. Biochemistry. 1996 Feb 20; 35(7):2112-6.
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Van Ophem PW, Pospischil MA, Ringe D, Peisach D, Petsko G, Soda K, Manning JM. Catalytic ability and stability of two recombinant mutants of D-amino acid transaminase involved in coenzyme binding. Protein Sci. 1995 Dec; 4(12):2578-86.
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Joseph-McCarthy D, Petsko GA, Karplus M. Use of a minimum perturbation approach to predict TIM mutant structures. Protein Eng. 1995 Nov; 8(11):1103-15.
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Petsko GA. Cancer chemotherapy. Heavy metal revival. Nature. 1995 Oct 19; 377(6550):580-1.
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Komives EA, Lougheed JC, Liu K, Sugio S, Zhang Z, Petsko GA, Ringe D. The structural basis for pseudoreversion of the E165D lesion by the secondary S96P mutation in triosephosphate isomerase depends on the positions of active site water molecules. Biochemistry. 1995 Oct 17; 34(41):13612-21.
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Kryger G, Wallon G, Lovett ST, Ringe D, Petsko GA. Revision of the amino-acid sequence of 3-isopropylmalate dehydrogenase from Salmonella typhimurium by means of X-ray crystallography. Gene. 1995 Oct 16; 164(1):85-7.
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Schiering N, Tao X, Zeng H, Murphy JR, Petsko GA, Ringe D. Structures of the apo- and the metal ion-activated forms of the diphtheria tox repressor from Corynebacterium diphtheriae. Proc Natl Acad Sci U S A. 1995 Oct 10; 92(21):9843-50.
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Warren GL, Petsko GA. Composition analysis of alpha-helices in thermophilic organisms. Protein Eng. 1995 Sep; 8(9):905-13.
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Sugio S, Petsko GA, Manning JM, Soda K, Ringe D. Crystal structure of a D-amino acid aminotransferase: how the protein controls stereoselectivity. Biochemistry. 1995 Aug 1; 34(30):9661-9.
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Peisach E, Casebier D, Gallion SL, Furth P, Petsko GA, Hogan JC, Ringe D. Interaction of a peptidomimetic aminimide inhibitor with elastase. Science. 1995 Jul 7; 269(5220):66-9.
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Hasson MS, Muscate A, Henehan GT, Guidinger PF, Petsko GA, Ringe D, Kenyon GL. Purification and crystallization of benzoylformate decarboxylase. Protein Sci. 1995 May; 4(5):955-9.
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Allen KN, Lavie A, Petsko GA, Ringe D. Design, synthesis, and characterization of a potent xylose isomerase inhibitor, D-threonohydroxamic acid, and high-resolution X-ray crystallographic structure of the enzyme-inhibitor complex. Biochemistry. 1995 Mar 21; 34(11):3742-9.
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Mattos C, Giammona DA, Petsko GA, Ringe D. Structural analysis of the active site of porcine pancreatic elastase based on the X-ray crystal structures of complexes with trifluoroacetyl-dipeptide-anilide inhibitors. Biochemistry. 1995 Mar 14; 34(10):3193-203.
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Mitra B, Kallarakal AT, Kozarich JW, Gerlt JA, Clifton JG, Petsko GA, Kenyon GL. Mechanism of the reaction catalyzed by mandelate racemase: importance of electrophilic catalysis by glutamic acid 317. Biochemistry. 1995 Mar 7; 34(9):2777-87.
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Kallarakal AT, Mitra B, Kozarich JW, Gerlt JA, Clifton JG, Petsko GA, Kenyon GL. Mechanism of the reaction catalyzed by mandelate racemase: structure and mechanistic properties of the K166R mutant. Biochemistry. 1995 Mar 7; 34(9):2788-97.
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Babbitt PC, Mrachko GT, Hasson MS, Huisman GW, Kolter R, Ringe D, Petsko GA, Kenyon GL, Gerlt JA. A functionally diverse enzyme superfamily that abstracts the alpha protons of carboxylic acids. Science. 1995 Feb 24; 267(5201):1159-61.
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Bohren KM, Wermuth B, Harrison D, Ringe D, Petsko GA, Gabbay KH. Expression, crystallization and preliminary crystallographic analysis of human carbonyl reductase. J Mol Biol. 1994 Dec 16; 244(5):659-64.
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Schiering N, Tao X, Murphy JR, Petsko GA, Ringe D. Crystallization and preliminary X-ray studies of the diphtheria Tox repressor from Corynebacterium diphtheriae. J Mol Biol. 1994 Dec 16; 244(5):654-6.
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Petsko GA. Biophysics. The little big bang. Nature. 1994 Oct 27; 371(6500):740-1.
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Ding X, Rasmussen BF, Petsko GA, Ringe D. Direct structural observation of an acyl-enzyme intermediate in the hydrolysis of an ester substrate by elastase. Biochemistry. 1994 Aug 9; 33(31):9285-93.
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Mattos C, Petsko GA, Karplus M. Analysis of two-residue turns in proteins. J Mol Biol. 1994 May 20; 238(5):733-47.
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Lavie A, Allen KN, Petsko GA, Ringe D. X-ray crystallographic structures of D-xylose isomerase-substrate complexes position the substrate and provide evidence for metal movement during catalysis. Biochemistry. 1994 May 10; 33(18):5469-80.
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Joseph-McCarthy D, Rost LE, Komives EA, Petsko GA. Crystal structure of the mutant yeast triosephosphate isomerase in which the catalytic base glutamic acid 165 is changed to aspartic acid. Biochemistry. 1994 Mar 15; 33(10):2824-9.
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Zhang Z, Sugio S, Komives EA, Liu KD, Knowles JR, Petsko GA, Ringe D. Crystal structure of recombinant chicken triosephosphate isomerase-phosphoglycolohydroxamate complex at 1.8-A resolution. Biochemistry. 1994 Mar 15; 33(10):2830-7.
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Joseph-McCarthy D, Lolis E, Komives EA, Petsko GA. Crystal structure of the K12M/G15A triosephosphate isomerase double mutant and electrostatic analysis of the active site. Biochemistry. 1994 Mar 15; 33(10):2815-23.
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Bohren KM, Grimshaw CE, Lai CJ, Harrison DH, Ringe D, Petsko GA, Gabbay KH. Tyrosine-48 is the proton donor and histidine-110 directs substrate stereochemical selectivity in the reduction reaction of human aldose reductase: enzyme kinetics and crystal structure of the Y48H mutant enzyme. Biochemistry. 1994 Mar 1; 33(8):2021-32.
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Harrison DH, Bohren KM, Ringe D, Petsko GA, Gabbay KH. An anion binding site in human aldose reductase: mechanistic implications for the binding of citrate, cacodylate, and glucose 6-phosphate. Biochemistry. 1994 Mar 1; 33(8):2011-20.
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Allen KN, Lavie A, Glasfeld A, Tanada TN, Gerrity DP, Carlson SC, Farber GK, Petsko GA, Ringe D. Role of the divalent metal ion in sugar binding, ring opening, and isomerization by D-xylose isomerase: replacement of a catalytic metal by an amino acid. Biochemistry. 1994 Feb 15; 33(6):1488-94.
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Allen KN, Lavie A, Farber GK, Glasfeld A, Petsko GA, Ringe D. Isotopic exchange plus substrate and inhibition kinetics of D-xylose isomerase do not support a proton-transfer mechanism. Biochemistry. 1994 Feb 15; 33(6):1481-7.
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Zhang YX, Shi Y, Zhou M, Petsko GA. Cloning, sequencing, and expression in Escherichia coli of the gene encoding a 45-kilodalton protein, elongation factor Tu, from Chlamydia trachomatis serovar F. J Bacteriol. 1994 Feb; 176(4):1184-7.
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Landro JA, Gerlt JA, Kozarich JW, Koo CW, Shah VJ, Kenyon GL, Neidhart DJ, Fujita S, Petsko GA. The role of lysine 166 in the mechanism of mandelate racemase from Pseudomonas putida: mechanistic and crystallographic evidence for stereospecific alkylation by (R)-alpha-phenylglycidate. Biochemistry. 1994 Jan 25; 33(3):635-43.
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Mattos C, Rasmussen B, Ding X, Petsko GA, Ringe D. Analogous inhibitors of elastase do not always bind analogously. Nat Struct Biol. 1994 Jan; 1(1):55-8.
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Stock AM, Martinez-Hackert E, Rasmussen BF, West AH, Stock JB, Ringe D, Petsko GA. Structure of the Mg(2+)-bound form of CheY and mechanism of phosphoryl transfer in bacterial chemotaxis. Biochemistry. 1993 Dec 14; 32(49):13375-80.
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Mitra B, Gerlt JA, Babbitt PC, Koo CW, Kenyon GL, Joseph D, Petsko GA. A novel structural basis for membrane association of a protein: construction of a chimeric soluble mutant of (S)-mandelate dehydrogenase from Pseudomonas putida. Biochemistry. 1993 Dec 7; 32(48):12959-67.
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Jeffrey PD, Strong RK, Sieker LC, Chang CY, Campbell RL, Petsko GA, Haber E, Margolies MN, Sheriff S. 26-10 Fab-digoxin complex: affinity and specificity due to surface complementarity. Proc Natl Acad Sci U S A. 1993 Nov 1; 90(21):10310-4.
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Petsko GA, Kenyon GL, Gerlt JA, Ringe D, Kozarich JW. On the origin of enzymatic species. Trends Biochem Sci. 1993 Oct; 18(10):372-6.
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Petsko GA. Left-handed comments. Science. 1992 Nov 20; 258(5086):1290.
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Kryger G, Petsko GA, Ouyang J, Viola RE. Crystallization and preliminary crystallographic analysis of aspartate-beta-semialdehyde dehydrogenase from Escherichia coli. J Mol Biol. 1992 Nov 5; 228(1):300-1.
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Petsko GA. Signal transduction. Fishing in Src-infested waters. Nature. 1992 Aug 20; 358(6388):625-6.
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Petsko GA. On the other hand... Science. 1992 Jun 5; 256(5062):1403-4.
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Rasmussen BF, Stock AM, Ringe D, Petsko GA. Crystalline ribonuclease A loses function below the dynamical transition at 220 K. Nature. 1992 Jun 4; 357(6377):423-4.
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Howell PL, Almo SC, Parsons MR, Hajdu J, Petsko GA. Structure determination of turkey egg-white lysozyme using Laue diffraction data. Acta Crystallogr B. 1992 Apr 1; 48 ( Pt 2):200-7.
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Tilton RF, Dewan JC, Petsko GA. Effects of temperature on protein structure and dynamics: X-ray crystallographic studies of the protein ribonuclease-A at nine different temperatures from 98 to 320 K. Biochemistry. 1992 Mar 10; 31(9):2469-81.
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Howell PL, Warren C, Amatayakul-Chantler S, Petsko GA, Hajdu J. Activity of crystalline turkey egg white lysozyme. Proteins. 1992 Jan; 12(1):91-9.
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Ringe D, Petsko GA. Viral proteases. Molecular metamorphosis. Nature. 1991 Nov 7; 354(6348):22-3.
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Neidhart DJ, Howell PL, Petsko GA, Powers VM, Li RS, Kenyon GL, Gerlt JA. Mechanism of the reaction catalyzed by mandelate racemase. 2. Crystal structure of mandelate racemase at 2.5-A resolution: identification of the active site and possible catalytic residues. Biochemistry. 1991 Sep 24; 30(38):9264-73.
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Petsko GA. Enzyme evolution. Déjà vu all over again. Nature. 1991 Jul 11; 352(6331):104-5.
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Stoddard BL, Koenigs P, Porter N, Petratos K, Petsko GA, Ringe D. Observation of the light-triggered binding of pyrone to chymotrypsin by Laue x-ray crystallography. Proc Natl Acad Sci U S A. 1991 Jul 1; 88(13):5503-7.
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Davenport RC, Bash PA, Seaton BA, Karplus M, Petsko GA, Ringe D. Structure of the triosephosphate isomerase-phosphoglycolohydroxamate complex: an analogue of the intermediate on the reaction pathway. Biochemistry. 1991 Jun 18; 30(24):5821-6.
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Bash PA, Field MJ, Davenport RC, Petsko GA, Ringe D, Karplus M. Computer simulation and analysis of the reaction pathway of triosephosphate isomerase. Biochemistry. 1991 Jun 18; 30(24):5826-32.
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Strong RK, Campbell R, Rose DR, Petsko GA, Sharon J, Margolies MN. Three-dimensional structure of murine anti-p-azophenylarsonate Fab 36-71. 1. X-ray crystallography, site-directed mutagenesis, and modeling of the complex with hapten. Biochemistry. 1991 Apr 16; 30(15):3739-48.
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Strong RK, Petsko GA, Sharon J, Margolies MN. Three-dimensional structure of murine anti-p-azophenylarsonate Fab 36-71. 2. Structural basis of hapten binding and idiotypy. Biochemistry. 1991 Apr 16; 30(15):3749-57.
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Komives EA, Chang LC, Lolis E, Tilton RF, Petsko GA, Knowles JR. Electrophilic catalysis in triosephosphate isomerase: the role of histidine-95. Biochemistry. 1991 Mar 26; 30(12):3011-9.
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Danishefsky AT, Onnufer JJ, Petsko GA, Ringe D. Activity and structure of the active-site mutants R386Y and R386F of Escherichia coli aspartate aminotransferase. Biochemistry. 1991 Feb 19; 30(7):1980-5.
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Stoddard BL, Ringe D, Petsko GA. The structure of iron superoxide dismutase from Pseudomonas ovalis complexed with the inhibitor azide. Protein Eng. 1990 Dec; 4(2):113-9.
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Neidhart DJ, Kenyon GL, Gerlt JA, Petsko GA. Mandelate racemase and muconate lactonizing enzyme are mechanistically distinct and structurally homologous. Nature. 1990 Oct 18; 347(6294):692-4.
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Karplus M, Petsko GA. Molecular dynamics simulations in biology. Nature. 1990 Oct 18; 347(6294):631-9.
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Stoddard BL, Howell PL, Ringe D, Petsko GA. The 2.1-A resolution structure of iron superoxide dismutase from Pseudomonas ovalis. Biochemistry. 1990 Sep 25; 29(38):8885-93.
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Joseph D, Petsko GA, Karplus M. Anatomy of a conformational change: hinged "lid" motion of the triosephosphate isomerase loop. Science. 1990 Sep 21; 249(4975):1425-8.
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Stoddard BL, Bruhnke J, Koenigs P, Porter N, Ringe D, Petsko GA. Photolysis and deacylation of inhibited chymotrypsin. Biochemistry. 1990 Sep 4; 29(35):8042-51.
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Pai EF, Krengel U, Petsko GA, Goody RS, Kabsch W, Wittinghofer A. Refined crystal structure of the triphosphate conformation of H-ras p21 at 1.35 A resolution: implications for the mechanism of GTP hydrolysis. EMBO J. 1990 Aug; 9(8):2351-9.
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Ringe D, Petsko GA. Cystic fibrosis. A transport problem? Nature. 1990 Jul 26; 346(6282):312-3.
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Lolis E, Alber T, Davenport RC, Rose D, Hartman FC, Petsko GA. Structure of yeast triosephosphate isomerase at 1.9-A resolution. Biochemistry. 1990 Jul 17; 29(28):6609-18.
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Lolis E, Petsko GA. Crystallographic analysis of the complex between triosephosphate isomerase and 2-phosphoglycolate at 2.5-A resolution: implications for catalysis. Biochemistry. 1990 Jul 17; 29(28):6619-25.
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Farber GK, Petsko GA. The evolution of alpha/beta barrel enzymes. Trends Biochem Sci. 1990 Jun; 15(6):228-34.
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Schlichting I, Almo SC, Rapp G, Wilson K, Petratos K, Lentfer A, Wittinghofer A, Kabsch W, Pai EF, Petsko GA, et al. Time-resolved X-ray crystallographic study of the conformational change in Ha-Ras p21 protein on GTP hydrolysis. Nature. 1990 May 24; 345(6273):309-15.
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Stoddard BL, Bruhnke J, Porter N, Ringe D, Petsko GA. Structure and activity of two photoreversible cinnamates bound to chymotrypsin. Biochemistry. 1990 May 22; 29(20):4871-9.
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Rose DR, Strong RK, Margolies MN, Gefter ML, Petsko GA. Crystal structure of the antigen-binding fragment of the murine anti-arsonate monoclonal antibody 36-71 at 2.9-A resolution. Proc Natl Acad Sci U S A. 1990 Jan; 87(1):338-42.
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Sicard PJ, Leleu JB, Duflot P, Drocourt D, Martin F, Tiraby G, Petsko G, Glasfeld A. Site-directed mutagenesis applied to glucose isomerase from Streptomyces violaceoniger and Streptomyces olivochromogenes. Ann N Y Acad Sci. 1990; 613:371-5.
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Neidhart DC, Howell PL, Petsko GA, Gerlt JA, Kozarich JW, Powers VM, Kenyon GL. Restructuring catalysis in the mandelate pathway. Biochem Soc Symp. 1990; 57:135-41.
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Lolis E, Petsko GA. Transition-state analogues in protein crystallography: probes of the structural source of enzyme catalysis. Annu Rev Biochem. 1990; 59:597-630.
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Petsko GA, Rees AR. Second structure determinations. Protein Eng. 1989 Nov; 3(2):67.
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Martinez del Pozo A, Pospischil MA, Ueno H, Manning JM, Tanizawa K, Nishimura K, Soda K, Ringe D, Stoddard B, Petsko GA. Effects of D-serine on bacterial D-amino acid transaminase: accumulation of an intermediate and inactivation of the enzyme. Biochemistry. 1989 Oct 31; 28(22):8798-803.
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Farber GK, Glasfeld A, Tiraby G, Ringe D, Petsko GA. Crystallographic studies of the mechanism of xylose isomerase. Biochemistry. 1989 Sep 5; 28(18):7289-97.
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Glasfeld A, Farber GK, Ringe D, Marcel T, Drocourt D, Tiraby G, Petsko GA. Characterization of crystals of xylose isomerase from Streptomyces violaceoniger. J Biol Chem. 1988 Oct 15; 263(29):14612-3.
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Neidhart DJ, Petsko GA. The refined crystal structure of subtilisin Carlsberg at 2.5 A resolution. Protein Eng. 1988 Oct; 2(4):271-6.
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Tilton RF, Petsko GA. A structure of sperm whale myoglobin at a nitrogen gas pressure of 145 atmospheres. Biochemistry. 1988 Aug 23; 27(17):6574-82.
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Nickbarg EB, Davenport RC, Petsko GA, Knowles JR. Triosephosphate isomerase: removal of a putatively electrophilic histidine residue results in a subtle change in catalytic mechanism. Biochemistry. 1988 Aug 9; 27(16):5948-60.
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Neidhart DJ, Powers VM, Kenyon GL, Tsou AY, Ransom SC, Gerlt JA, Petsko GA. Preliminary x-ray data on crystals of mandelate racemase. J Biol Chem. 1988 Jul 5; 263(19):9268-70.
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Farber GK, Machin P, Almo SC, Petsko GA, Hajdu J. X-ray Laue diffraction from crystals of xylose isomerase. Proc Natl Acad Sci U S A. 1988 Jan; 85(1):112-5.
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Burley SK, Petsko GA. Weakly polar interactions in proteins. Adv Protein Chem. 1988; 39:125-89.
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Campbell RL, Petsko GA. Ribonuclease structure and catalysis: crystal structure of sulfate-free native ribonuclease A at 1.5-A resolution. Biochemistry. 1987 Dec 29; 26(26):8579-84.
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Farber GK, Petsko GA, Ringe D. The 3.0 A crystal structure of xylose isomerase from Streptomyces olivochromogenes. Protein Eng. 1987 Dec; 1(6):459-66.
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Neidhart DJ, Distefano MD, Tanizawa K, Soda K, Walsh CT, Petsko GA. X-ray crystallographic studies of the alanine-specific racemase from Bacillus stearothermophilus. Overproduction, crystallization, and preliminary characterization. J Biol Chem. 1987 Nov 15; 262(32):15323-6.
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Kozelka J, Archer S, Petsko GA, Lippard SJ, Quigley GJ. Molecular mechanics modeling of oligonucleotide adducts of the antitumor drug cis-diamminedichloroplatinum(II). Biopolymers. 1987 Aug; 26(8):1245-71.
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Stoddard B, Howell L, Asano S, Soda K, Tanizawa K, Ringe D, Petsko GA. Preliminary X-ray data for a D-amino acid amino-transferase from a novel thermophilic Bacillus. J Mol Biol. 1987 Jul 20; 196(2):441-2.
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Casal JI, Ahern TJ, Davenport RC, Petsko GA, Klibanov AM. Subunit interface of triosephosphate isomerase: site-directed mutagenesis and characterization of the altered enzyme. Biochemistry. 1987 Mar 10; 26(5):1258-64.
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Brünger AT, Campbell RL, Clore GM, Gronenborn AM, Karplus M, Petsko GA, Teeter MM. Solution of a protein crystal structure with a model obtained from NMR interproton distance restraints. Science. 1987 Feb 27; 235(4792):1049-53.
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Ahern TJ, Casal JI, Petsko GA, Klibanov AM. Control of oligomeric enzyme thermostability by protein engineering. Proc Natl Acad Sci U S A. 1987 Feb; 84(3):675-9.
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Frauenfelder H, Hartmann H, Karplus M, Kuntz ID, Kuriyan J, Parak F, Petsko GA, Ringe D, Tilton RF, Connolly ML, et al. Thermal expansion of a protein. Biochemistry. 1987 Jan 13; 26(1):254-61.
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Kuriyan J, Karplus M, Petsko GA. Estimation of uncertainties in X-ray refinement results by use of perturbed structures. Proteins. 1987; 2(1):1-12.
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Alber TC, Davenport RC, Giammona DA, Lolis E, Petsko GA, Ringe D. Crystallography and site-directed mutagenesis of yeast triosephosphate isomerase: what can we learn about catalysis from a "simple" enzyme? Cold Spring Harb Symp Quant Biol. 1987; 52:603-13.
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Kuriyan J, Wilz S, Karplus M, Petsko GA. X-ray structure and refinement of carbon-monoxy (Fe II)-myoglobin at 1.5 A resolution. J Mol Biol. 1986 Nov 5; 192(1):133-54.
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Burley SK, Petsko GA. Amino-aromatic interactions in proteins. FEBS Lett. 1986 Jul 28; 203(2):139-43.
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Kuriyan J, Petsko GA, Levy RM, Karplus M. Effect of anisotropy and anharmonicity on protein crystallographic refinement. An evaluation by molecular dynamics. J Mol Biol. 1986 Jul 20; 190(2):227-54.
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Ringe D, Petsko GA. Study of protein dynamics by X-ray diffraction. Methods Enzymol. 1986; 131:389-433.
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Burley SK, Petsko GA. Aromatic-aromatic interaction: a mechanism of protein structure stabilization. Science. 1985 Jul 5; 229(4708):23-8.
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Petsko GA. Diffraction methods for biological macromolecules. Flow cell construction and use. Methods Enzymol. 1985; 114:141-6.
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Ringe D, Petsko GA. Mapping protein dynamics by X-ray diffraction. Prog Biophys Mol Biol. 1985; 45(3):197-235.
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Petsko GA. Preparation of isomorphous heavy-atom derivatives. Methods Enzymol. 1985; 114:147-56.
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Seaton BA, Campbell RL, Petsko GA, Rose DR, Edelstein I, Marcus F. Preliminary X-ray crystallographic studies of pig kidney fructose-1,6-bisphosphatase. J Biol Chem. 1984 Jul 25; 259(14):8915-6.
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Tilton RF, Kuntz ID, Petsko GA. Cavities in proteins: structure of a metmyoglobin-xenon complex solved to 1.9 A. Biochemistry. 1984 Jun 19; 23(13):2849-57.
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Petsko GA, Davenport RC, Frankel D, RaiBhandary UL. Probing the catalytic mechanism of yeast triose phosphate isomerase by site-specific mutagenesis. Biochem Soc Trans. 1984 Apr; 12(2):229-32.
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Ringe D, Petsko GA, Kerr DE, Ortiz de Montellano PR. Reaction of myoglobin with phenylhydrazine: a molecular doorstop. Biochemistry. 1984 Jan 3; 23(1):2-4.
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Petsko GA, Ringe D. Fluctuations in protein structure from X-ray diffraction. Annu Rev Biophys Bioeng. 1984; 13:331-71.
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Douzou P, Petsko GA. Proteins at work: "stop-action" pictures at subzero temperatures. Adv Protein Chem. 1984; 36:245-361.
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Mowbray SL, Petsko GA. The x-ray structure of the periplasmic galactose binding protein from Salmonella typhimurium at 3.0-A resolution. J Biol Chem. 1983 Jul 10; 258(13):7991-7.
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Ringe D, Petsko GA, Yamakura F, Suzuki K, Ohmori D. Structure of iron superoxide dismutase from Pseudomonas ovalis at 2.9-A resolution. Proc Natl Acad Sci U S A. 1983 Jul; 80(13):3879-83.
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Mowbray SL, Petsko GA. The introduction of specific sites for heavy metal binding in a crystalline protein. J Biol Chem. 1983 May 10; 258(9):5634-7.
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Smith WW, Pattridge KA, Ludwig ML, Petsko GA, Tsernoglou D, Tanaka M, Yasunobu KT. Structure of oxidized flavodoxin from Anacystis nidulans. J Mol Biol. 1983 Apr 25; 165(4):737-53.
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Ringe D, Petsko GA, Yamakura F, Suzuki K, Ohmori D. The iron content of iron superoxide dismutase: determination by anomalous scattering. Proc R Soc Lond B Biol Sci. 1983 Apr 22; 218(1210):119-26.
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Rose DR, Seaton BA, Petsko GA, Novotný J, Margolies MN, Locke E, Haber E. Crystallization of the Fab fragment of a monoclonal anti-digoxin antibody and its complex with digoxin. J Mol Biol. 1983 Mar 25; 165(1):203-6.
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Seaton BA, Head JF, Lord RC, Petsko GA. Studies of calmodulin structure: laser raman spectroscopy of biomolecules. Biochemistry. 1983 Feb 15; 22(4):973-8.
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Alber T, Gilbert WA, Ponzi DR, Petsko GA. The role of mobility in the substrate binding and catalytic machinery of enzymes. Ciba Found Symp. 1983; 93:4-24.
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Mowbray SL, Petsko GA. Preliminary X-ray data for the ribose binding protein from Salmonella typhimurium. J Mol Biol. 1982 Sep 25; 160(3):545-7.
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Hartmann H, Parak F, Steigemann W, Petsko GA, Ponzi DR, Frauenfelder H. Conformational substates in a protein: structure and dynamics of metmyoglobin at 80 K. Proc Natl Acad Sci U S A. 1982 Aug; 79(16):4967-71.
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Pinn E, Pähler A, Saenger W, Petsko GA, Green NM. Crystallization and preliminary X-ray investigation of avidin. Eur J Biochem. 1982 Apr; 123(3):545-6.
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Alber T, Banner DW, Bloomer AC, Petsko GA, Phillips D, Rivers PS, Wilson IA. On the three-dimensional structure and catalytic mechanism of triose phosphate isomerase. Philos Trans R Soc Lond B Biol Sci. 1981 Jun 26; 293(1063):159-71.
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Alber T, Fahnestock M, Mowbray SL, Petsko GA. Preliminary x-ray data for the galactose binding protein from Salmonella typhimurium. J Mol Biol. 1981 Apr 15; 147(3):471-4.
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Alber T, Hartman FC, Johnson RM, Petsko GA, Tsernoglou D. Crystallization of yeast triose phosphate isomerase from polyethylene glycol. Protein crystal formation following phase separation. J Biol Chem. 1981 Feb 10; 256(3):1356-61.
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Fink AL, Petsko GA. X-ray cryoenzymology. Adv Enzymol Relat Areas Mol Biol. 1981; 52:177-246.
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Frauenfelder H, Petsko GA. Structural dynamics of liganded myoglobin. Biophys J. 1980 Oct; 32(1):465-83.
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Frauenfelder H, Petsko GA, Tsernoglou D. Temperature-dependent X-ray diffraction as a probe of protein structural dynamics. Nature. 1979 Aug 16; 280(5723):558-63.
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Tsernoglou D, Petsko GA, Hudson RA. Structure and function of snake venom curarimimetic neurotoxins. Mol Pharmacol. 1978 Jul; 14(4):710-6.
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Petsko GA, Phillips DC, Williams RJ, Wilson IA. On the protein crystal chemistry of chloroplatinite ions: general principles and interactions with triose phosphate isomerase. J Mol Biol. 1978 Apr 15; 120(3):345-59.
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Tsernoglou D, Petsko GA, McQueen JE, Hermans J. Molecular graphics: application to the structure determination of a snake venom neurotoxin. Science. 1977 Sep 30; 197(4311):1378-81.
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Tsernoglou D, Petsko GA, Tu AT. Protein sequencing by computer graphics. Biochim Biophys Acta. 1977 Apr 25; 491(2):605-8.
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Tsernoglou D, Petsko GA. Three-dimensional structure of neurotoxin a from venom of the Philippines sea snake. Proc Natl Acad Sci U S A. 1977 Mar; 74(3):971-4.
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Martin PD, Petsko GA, Tsernoglou D. New high pH crystal forms of ribonucleases A and S. J Mol Biol. 1976 Nov; 108(1):265-9.
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Alber T, Petsko GA, Tsernoglou D. Crystal structure of elastase-substrate complex at -- 55 degrees C. Nature. 1976 Sep 23; 263(5575):297-300.
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Tsernoglou D, Petsko GA. The crystal structure of a post-synaptic neurotoxin from sea snake at A resolution. FEBS Lett. 1976 Sep 15; 68(1):1-4.
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Petsko GA, Tsernoglou D. The structure of subtilopeptidase A. I. X-ray crystallographic data. J Mol Biol. 1976 Sep 15; 106(2):453-6.
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Banner DW, Bloomer Ac, Petsko GA, Phillips DC, Wilson IA. Atomic coordinates for triose phosphate isomerase from chicken muscle. Biochem Biophys Res Commun. 1976 Sep 7; 72(1):146-55.
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Douzou P, Hoa GH, Petsko GA. Protein crystallography at sub-zero temperatures: lysozyme-substrate complexes in cooled mixed solvents. J Mol Biol. 1975 Aug 15; 96(3):367-80.
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Petsko GA. Protein crystallography at sub-zero temperatures: cryo-protective mother liquors for protein crystals. J Mol Biol. 1975 Aug 15; 96(3):381-92.
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Banner DW, Bloomer AC, Petsko GA, Phillips DC, Pogson CI, Wilson IA, Corran PH, Furth AJ, Milman JD, Offord RE, Priddle JD, Waley SG. Structure of chicken muscle triose phosphate isomerase determined crystallographically at 2.5 angstrom resolution using amino acid sequence data. Nature. 1975 Jun 19; 255(5510):609-14.
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Banner DW, Bloomer AC, Petsko GA, Phillips DC, Pogson CI. Crystallographic studies of chicken triose phosphate isomerase. Cold Spring Harb Symp Quant Biol. 1972; 36:151-5.
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Petsko GA. Proton magnetic resonance spectrum of polywater. Science. 1970 Jan 9; 167(3915):171.
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