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Keywords
Last Name
Institution

Nicholas John Dyson, PH.D.

TitleProfessor of Medicine
InstitutionMassachusetts General Hospital
DepartmentMedicine
AddressMassachusetts General Hospital
MGH Cancer Center
149 13th Street
Charlestown MA 02129
Phone617/726-7800
Fax617/726-7808

 Bibliographic 
 selected publications
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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  1. Evertts AG, Manning AL, Wang X, Dyson NJ, Garcia BA, Coller HA. H4K20 methylation regulates quiescence and chromatin compaction. Mol Biol Cell. 2013 Oct; 24(19):3025-37.
    View in: PubMed
  2. Nicolay BN, Dyson NJ. The multiple connections between pRB and cell metabolism. Curr Opin Cell Biol. 2013 Dec; 25(6):735-40.
    View in: PubMed
  3. Black JC, Manning AL, Van Rechem C, Kim J, Ladd B, Cho J, Pineda CM, Murphy N, Daniels DL, Montagna C, Lewis PW, Glass K, Allis CD, Dyson NJ, Getz G, Whetstine JR. KDM4A Lysine Demethylase Induces Site-Specific Copy Gain and Rereplication of Regions Amplified in Tumors. Cell. 2013 Aug 1; 154(3):541-55.
    View in: PubMed
  4. Nicolay BN, Gameiro PA, Tschöp K, Korenjak M, Heilmann AM, Asara JM, Stephanopoulos G, Iliopoulos O, Dyson NJ. Loss of RBF1 changes glutamine catabolism. Genes Dev. 2013 Jan 15; 27(2):182-96.
    View in: PubMed
  5. Ji JY, Miles WO, Korenjak M, Zheng Y, Dyson NJ. In Vivo Regulation of E2F1 by Polycomb Group Genes in Drosophila. G3 (Bethesda). 2012 Dec; 2(12):1651-60.
    View in: PubMed
  6. Herr A, Longworth M, Ji JY, Korenjak M, Macalpine DM, Dyson NJ. Identification of E2F target genes that are rate limiting for dE2F1-dependent cell proliferation. Dev Dyn. 2012 Nov; 241(11):1695-707.
    View in: PubMed
  7. Korenjak M, Anderssen E, Ramaswamy S, Whetstine JR, Dyson NJ. RBF Binding to both Canonical E2F Targets and Noncanonical Targets Depends on Functional dE2F/dDP Complexes. Mol Cell Biol. 2012 Nov; 32(21):4375-87.
    View in: PubMed
  8. Nicolay BN, Dyson NJ. It's all in the timing: too much E2F is a bad thing. PLoS Genet. 2012; 8(8):e1002909.
    View in: PubMed
  9. Heilmann AM, Dyson NJ. Phosphorylation puts the pRb tumor suppressor into shape. Genes Dev. 2012 Jun 1; 26(11):1128-30.
    View in: PubMed
  10. Longworth MS, Walker JA, Anderssen E, Moon NS, Gladden A, Heck MM, Ramaswamy S, Dyson NJ. A shared role for RBF1 and dCAP-D3 in the regulation of transcription with consequences for innate immunity. PLoS Genet. 2012; 8(4):e1002618.
    View in: PubMed
  11. Miles WO, Tschöp K, Herr A, Ji JY, Dyson NJ. Pumilio facilitates miRNA regulation of the E2F3 oncogene. Genes Dev. 2012 Feb 15; 26(4):356-68.
    View in: PubMed
  12. Manning AL, Dyson NJ. RB: mitotic implications of a tumour suppressor. Nat Rev Cancer. 2012 Mar; 12(3):220-6.
    View in: PubMed
  13. Zhang J, Benavente CA, McEvoy J, Flores-Otero J, Ding L, Chen X, Ulyanov A, Wu G, Wilson M, Wang J, Brennan R, Rusch M, Manning AL, Ma J, Easton J, Shurtleff S, Mullighan C, Pounds S, Mukatira S, Gupta P, Neale G, Zhao D, Lu C, Fulton RS, Fulton LL, Hong X, Dooling DJ, Ochoa K, Naeve C, Dyson NJ, Mardis ER, Bahrami A, Ellison D, Wilson RK, Downing JR, Dyer MA. A novel retinoblastoma therapy from genomic and epigenetic analyses. Nature. 2012 Jan 19; 481(7381):329-34.
    View in: PubMed
  14. Popova MK, He W, Korenjak M, Dyson NJ, Moon NS. Rb deficiency during Drosophila eye development deregulates EMC, causing defects in the development of photoreceptors and cone cells. J Cell Sci. 2011 Dec 15; 124(Pt 24):4203-12.
    View in: PubMed
  15. Tschöp K, Dyson N. Identifying players in the functional network around pRB. Cell Cycle. 2011 Nov 15; 10(22):3814-5.
    View in: PubMed
  16. Miles WO, Dyson NJ, Walker JA. Modeling tumor invasion and metastasis in Drosophila. Dis Model Mech. 2011 Nov; 4(6):753-61.
    View in: PubMed
  17. Di Stefano L, Dyson NJ. The complex roles of histone demethylases in vivo. Cell Cycle. 2011 Jul 1; 10(13):2049-50.
    View in: PubMed
  18. Manning AL, Dyson NJ. pRB, a tumor suppressor with a stabilizing presence. Trends Cell Biol. 2011 Aug; 21(8):433-41.
    View in: PubMed
  19. Mulligan P, Yang F, Di Stefano L, Ji JY, Ouyang J, Nishikawa JL, Toiber D, Kulkarni M, Wang Q, Najafi-Shoushtari SH, Mostoslavsky R, Gygi SP, Gill G, Dyson NJ, Näär AM. A SIRT1-LSD1 corepressor complex regulates Notch target gene expression and development. Mol Cell. 2011 Jun 10; 42(5):689-99.
    View in: PubMed
  20. Tschöp K, Conery AR, Litovchick L, Decaprio JA, Settleman J, Harlow E, Dyson N. A kinase shRNA screen links LATS2 and the pRB tumor suppressor. Genes Dev. 2011 Apr 15; 25(8):814-30.
    View in: PubMed
  21. Di Stefano L, Walker JA, Burgio G, Corona DF, Mulligan P, Näär AM, Dyson NJ. Functional antagonism between histone H3K4 demethylases in vivo. Genes Dev. 2011 Jan 1; 25(1):17-28.
    View in: PubMed
  22. Black JC, Allen A, Van Rechem C, Forbes E, Longworth M, Tschöp K, Rinehart C, Quiton J, Walsh R, Smallwood A, Dyson NJ, Whetstine JR. Conserved antagonism between JMJD2A/KDM4A and HP1? during cell cycle progression. Mol Cell. 2010 Dec 10; 40(5):736-48.
    View in: PubMed
  23. Centore RC, Havens CG, Manning AL, Li JM, Flynn RL, Tse A, Jin J, Dyson NJ, Walter JC, Zou L. CRL4(Cdt2)-mediated destruction of the histone methyltransferase Set8 prevents premature chromatin compaction in S phase. Mol Cell. 2010 Oct 8; 40(1):22-33.
    View in: PubMed
  24. Walker AK, Yang F, Jiang K, Ji JY, Watts JL, Purushotham A, Boss O, Hirsch ML, Ribich S, Smith JJ, Israelian K, Westphal CH, Rodgers JT, Shioda T, Elson SL, Mulligan P, Najafi-Shoushtari H, Black JC, Thakur JK, Kadyk LC, Whetstine JR, Mostoslavsky R, Puigserver P, Li X, Dyson NJ, Hart AC, Näär AM. Conserved role of SIRT1 orthologs in fasting-dependent inhibition of the lipid/cholesterol regulator SREBP. Genes Dev. 2010 Jul 1; 24(13):1403-17.
    View in: PubMed
  25. Manning AL, Longworth MS, Dyson NJ. Loss of pRB causes centromere dysfunction and chromosomal instability. Genes Dev. 2010 Jul 1; 24(13):1364-76.
    View in: PubMed
  26. Zhang J, Ji JY, Yu M, Overholtzer M, Smolen GA, Wang R, Brugge JS, Dyson NJ, Haber DA. YAP-dependent induction of amphiregulin identifies a non-cell-autonomous component of the Hippo pathway. Nat Cell Biol. 2009 Dec; 11(12):1444-50.
    View in: PubMed
  27. Longworth MS, Dyson NJ. pRb, a local chromatin organizer with global possibilities. Chromosoma. 2010 Feb; 119(1):1-11.
    View in: PubMed
  28. Gao D, Inuzuka H, Korenjak M, Tseng A, Wu T, Wan L, Kirschner M, Dyson N, Wei W. Cdh1 regulates cell cycle through modulating the claspin/Chk1 and the Rb/E2F1 pathways. Mol Biol Cell. 2009 Jul; 20(14):3305-16.
    View in: PubMed
  29. Korenjak M, Dyson N. A vanishing act, explained. Dev Cell. 2008 Dec; 15(6):793-4.
    View in: PubMed
  30. Morris EJ, Ji JY, Yang F, Di Stefano L, Herr A, Moon NS, Kwon EJ, Haigis KM, Näär AM, Dyson NJ. E2F1 represses beta-catenin transcription and is antagonized by both pRB and CDK8. Nature. 2008 Sep 25; 455(7212):552-6.
    View in: PubMed
  31. van den Heuvel S, Dyson NJ. Conserved functions of the pRB and E2F families. Nat Rev Mol Cell Biol. 2008 Sep; 9(9):713-24.
    View in: PubMed
  32. Moon NS, Di Stefano L, Morris EJ, Patel R, White K, Dyson NJ. E2F and p53 induce apoptosis independently during Drosophila development but intersect in the context of DNA damage. PLoS Genet. 2008; 4(8):e1000153.
    View in: PubMed
  33. Longworth MS, Herr A, Ji JY, Dyson NJ. RBF1 promotes chromatin condensation through a conserved interaction with the Condensin II protein dCAP-D3. Genes Dev. 2008 Apr 15; 22(8):1011-24.
    View in: PubMed
  34. Moon NS, Dyson N. E2F7 and E2F8 keep the E2F family in balance. Dev Cell. 2008 Jan; 14(1):1-3.
    View in: PubMed
  35. Di Stefano L, Ji JY, Moon NS, Herr A, Dyson N. Mutation of Drosophila Lsd1 disrupts H3-K4 methylation, resulting in tissue-specific defects during development. Curr Biol. 2007 May 1; 17(9):808-12.
    View in: PubMed
  36. Binné UK, Classon MK, Dick FA, Wei W, Rape M, Kaelin WG, Näär AM, Dyson NJ. Retinoblastoma protein and anaphase-promoting complex physically interact and functionally cooperate during cell-cycle exit. Nat Cell Biol. 2007 Feb; 9(2):225-32.
    View in: PubMed
  37. Morris EJ, Michaud WA, Ji JY, Moon NS, Rocco JW, Dyson NJ. Functional identification of Api5 as a suppressor of E2F-dependent apoptosis in vivo. PLoS Genet. 2006 Nov 17; 2(11):e196.
    View in: PubMed
  38. Balsitis S, Dick F, Dyson N, Lambert PF. Critical roles for non-pRb targets of human papillomavirus type 16 E7 in cervical carcinogenesis. Cancer Res. 2006 Oct 1; 66(19):9393-400.
    View in: PubMed
  39. Moon NS, Di Stefano L, Dyson N. A gradient of epidermal growth factor receptor signaling determines the sensitivity of rbf1 mutant cells to E2F-dependent apoptosis. Mol Cell Biol. 2006 Oct; 26(20):7601-15.
    View in: PubMed
  40. Isaac CE, Francis SM, Martens AL, Julian LM, Seifried LA, Erdmann N, Binné UK, Harrington L, Sicinski P, Bérubé NG, Dyson NJ, Dick FA. The retinoblastoma protein regulates pericentric heterochromatin. Mol Cell Biol. 2006 May; 26(9):3659-71.
    View in: PubMed
  41. Moon NS, Frolov MV, Kwon EJ, Di Stefano L, Dimova DK, Morris EJ, Taylor-Harding B, White K, Dyson NJ. Drosophila E2F1 has context-specific pro- and antiapoptotic properties during development. Dev Cell. 2005 Oct; 9(4):463-75.
    View in: PubMed
  42. Stevaux O, Dimova DK, Ji JY, Moon NS, Frolov MV, Dyson NJ. Retinoblastoma family 2 is required in vivo for the tissue-specific repression of dE2F2 target genes. Cell Cycle. 2005 Sep; 4(9):1272-80.
    View in: PubMed
  43. Balsitis S, Dick F, Lee D, Farrell L, Hyde RK, Griep AE, Dyson N, Lambert PF. Examination of the pRb-dependent and pRb-independent functions of E7 in vivo. J Virol. 2005 Sep; 79(17):11392-402.
    View in: PubMed
  44. Dimova DK, Dyson NJ. The E2F transcriptional network: old acquaintances with new faces. Oncogene. 2005 Apr 18; 24(17):2810-26.
    View in: PubMed
  45. Frolov MV, Moon NS, Dyson NJ. dDP is needed for normal cell proliferation. Mol Cell Biol. 2005 Apr; 25(8):3027-39.
    View in: PubMed
  46. Taylor-Harding B, Binné UK, Korenjak M, Brehm A, Dyson NJ. p55, the Drosophila ortholog of RbAp46/RbAp48, is required for the repression of dE2F2/RBF-regulated genes. Mol Cell Biol. 2004 Oct; 24(20):9124-36.
    View in: PubMed
  47. Frolov MV, Dyson NJ. Molecular mechanisms of E2F-dependent activation and pRB-mediated repression. J Cell Sci. 2004 May 1; 117(Pt 11):2173-81.
    View in: PubMed
  48. Barbie DA, Kudlow BA, Frock R, Zhao J, Johnson BR, Dyson N, Harlow E, Kennedy BK. Nuclear reorganization of mammalian DNA synthesis prior to cell cycle exit. Mol Cell Biol. 2004 Jan; 24(2):595-607.
    View in: PubMed
  49. Dimova DK, Stevaux O, Frolov MV, Dyson NJ. Cell cycle-dependent and cell cycle-independent control of transcription by the Drosophila E2F/RB pathway. Genes Dev. 2003 Sep 15; 17(18):2308-20.
    View in: PubMed
  50. Kohn MJ, Bronson RT, Harlow E, Dyson NJ, Yamasaki L. Dp1 is required for extra-embryonic development. Development. 2003 Apr; 130(7):1295-305.
    View in: PubMed
  51. Frolov MV, Stevaux O, Moon NS, Dimova D, Kwon EJ, Morris EJ, Dyson NJ. G1 cyclin-dependent kinases are insufficient to reverse dE2F2-mediated repression. Genes Dev. 2003 Mar 15; 17(6):723-8.
    View in: PubMed
  52. Stevaux O, Dyson NJ. A revised picture of the E2F transcriptional network and RB function. Curr Opin Cell Biol. 2002 Dec; 14(6):684-91.
    View in: PubMed
  53. Stevaux O, Dimova D, Frolov MV, Taylor-Harding B, Morris E, Dyson N. Distinct mechanisms of E2F regulation by Drosophila RBF1 and RBF2. EMBO J. 2002 Sep 16; 21(18):4927-37.
    View in: PubMed
  54. Dick FA, Dyson NJ. Three regions of the pRB pocket domain affect its inactivation by human papillomavirus E7 proteins. J Virol. 2002 Jun; 76(12):6224-34.
    View in: PubMed
  55. Chakravarti A, Noll E, Black PM, Finkelstein DF, Finkelstein DM, Dyson NJ, Loeffler JS. Quantitatively determined survivin expression levels are of prognostic value in human gliomas. J Clin Oncol. 2002 Feb 15; 20(4):1063-8.
    View in: PubMed
  56. Chakravarti A, Loeffler JS, Dyson NJ. Insulin-like growth factor receptor I mediates resistance to anti-epidermal growth factor receptor therapy in primary human glioblastoma cells through continued activation of phosphoinositide 3-kinase signaling. Cancer Res. 2002 Jan 1; 62(1):200-7.
    View in: PubMed
  57. Geng Y, Yu Q, Whoriskey W, Dick F, Tsai KY, Ford HL, Biswas DK, Pardee AB, Amati B, Jacks T, Richardson A, Dyson N, Sicinski P. Expression of cyclins E1 and E2 during mouse development and in neoplasia. Proc Natl Acad Sci U S A. 2001 Nov 6; 98(23):13138-43.
    View in: PubMed
  58. Frolov MV, Huen DS, Stevaux O, Dimova D, Balczarek-Strang K, Elsdon M, Dyson NJ. Functional antagonism between E2F family members. Genes Dev. 2001 Aug 15; 15(16):2146-60.
    View in: PubMed
  59. Chakravarti A, Delaney MA, Noll E, Black PM, Loeffler JS, Muzikansky A, Dyson NJ. Prognostic and pathologic significance of quantitative protein expression profiling in human gliomas. Clin Cancer Res. 2001 Aug; 7(8):2387-95.
    View in: PubMed
  60. Morris EJ, Keramaris E, Rideout HJ, Slack RS, Dyson NJ, Stefanis L, Park DS. Cyclin-dependent kinases and P53 pathways are activated independently and mediate Bax activation in neurons after DNA damage. J Neurosci. 2001 Jul 15; 21(14):5017-26.
    View in: PubMed
  61. Kennedy BK, Liu OW, Dick FA, Dyson N, Harlow E, Vidal M. Histone deacetylase-dependent transcriptional repression by pRB in yeast occurs independently of interaction through the LXCXE binding cleft. Proc Natl Acad Sci U S A. 2001 Jul 17; 98(15):8720-5.
    View in: PubMed
  62. Pennaneach V, Salles-Passador I, Munshi A, Brickner H, Regazzoni K, Dick F, Dyson N, Chen TT, Wang JY, Fotedar R, Fotedar A. The large subunit of replication factor C promotes cell survival after DNA damage in an LxCxE motif- and Rb-dependent manner. Mol Cell. 2001 Apr; 7(4):715-27.
    View in: PubMed
  63. Classon M, Dyson N. p107 and p130: versatile proteins with interesting pockets. Exp Cell Res. 2001 Mar 10; 264(1):135-47.
    View in: PubMed
  64. Morris EJ, Dyson NJ. Retinoblastoma protein partners. Adv Cancer Res. 2001; 82:1-54.
    View in: PubMed
  65. Kennedy BK, Barbie DA, Classon M, Dyson N, Harlow E. Nuclear organization of DNA replication in primary mammalian cells. Genes Dev. 2000 Nov 15; 14(22):2855-68.
    View in: PubMed
  66. Boulton SJ, Brook A, Staehling-Hampton K, Heitzler P, Dyson N. A role for Ebi in neuronal cell cycle control. EMBO J. 2000 Oct 16; 19(20):5376-86.
    View in: PubMed
  67. Bruce JL, Hurford RK, Classon M, Koh J, Dyson N. Requirements for cell cycle arrest by p16INK4a. Mol Cell. 2000 Sep; 6(3):737-42.
    View in: PubMed
  68. Dick FA, Sailhamer E, Dyson NJ. Mutagenesis of the pRB pocket reveals that cell cycle arrest functions are separable from binding to viral oncoproteins. Mol Cell Biol. 2000 May; 20(10):3715-27.
    View in: PubMed
  69. Giovanni A, Keramaris E, Morris EJ, Hou ST, O'Hare M, Dyson N, Robertson GS, Slack RS, Park DS. E2F1 mediates death of B-amyloid-treated cortical neurons in a manner independent of p53 and dependent on Bax and caspase 3. J Biol Chem. 2000 Apr 21; 275(16):11553-60.
    View in: PubMed
  70. Staehling-Hampton K, Ciampa PJ, Brook A, Dyson N. A genetic screen for modifiers of E2F in Drosophila melanogaster. Genetics. 1999 Sep; 153(1):275-87.
    View in: PubMed
  71. McCaffrey J, Yamasaki L, Dyson NJ, Harlow E, Griep AE. Disruption of retinoblastoma protein family function by human papillomavirus type 16 E7 oncoprotein inhibits lens development in part through E2F-1. Mol Cell Biol. 1999 Sep; 19(9):6458-68.
    View in: PubMed
  72. Lukas ER, Bartley SM, Graveel CR, Diaz ZM, Dyson N, Harlow E, Yamasaki L, Farnham PJ. No effect of loss of E2F1 on liver regeneration or hepatocarcinogenesis in C57BL/6J or C3H/HeJ mice. Mol Carcinog. 1999 Aug; 25(4):295-303.
    View in: PubMed
  73. Du W, Dyson N. The role of RBF in the introduction of G1 regulation during Drosophila embryogenesis. EMBO J. 1999 Feb 15; 18(4):916-25.
    View in: PubMed
  74. Dyson N, Balmain A. Oncogenes and cell proliferation. Curr Opin Genet Dev. 1999 Feb; 9(1):11-4.
    View in: PubMed
  75. Harrington EA, Bruce JL, Harlow E, Dyson N. pRB plays an essential role in cell cycle arrest induced by DNA damage. Proc Natl Acad Sci U S A. 1998 Sep 29; 95(20):11945-50.
    View in: PubMed
  76. Pan H, Yin C, Dyson NJ, Harlow E, Yamasaki L, Van Dyke T. Key roles for E2F1 in signaling p53-dependent apoptosis and in cell division within developing tumors. Mol Cell. 1998 Sep; 2(3):283-92.
    View in: PubMed
  77. Dyson N. The regulation of E2F by pRB-family proteins. Genes Dev. 1998 Aug 1; 12(15):2245-62.
    View in: PubMed
  78. Yamasaki L, Bronson R, Williams BO, Dyson NJ, Harlow E, Jacks T. Loss of E2F-1 reduces tumorigenesis and extends the lifespan of Rb1(+/-)mice. Nat Genet. 1998 Apr; 18(4):360-4.
    View in: PubMed
  79. Hurford RK, Cobrinik D, Lee MH, Dyson N. pRB and p107/p130 are required for the regulated expression of different sets of E2F responsive genes. Genes Dev. 1997 Jun 1; 11(11):1447-63.
    View in: PubMed
  80. Duronio RJ, Brook A, Dyson N, O'Farrell PH. E2F-induced S phase requires cyclin E. Genes Dev. 1996 Oct 1; 10(19):2505-13.
    View in: PubMed
  81. Brook A, Xie JE, Du W, Dyson N. Requirements for dE2F function in proliferating cells and in post-mitotic differentiating cells. EMBO J. 1996 Jul 15; 15(14):3676-83.
    View in: PubMed
  82. Du W, Xie JE, Dyson N. Ectopic expression of dE2F and dDP induces cell proliferation and death in the Drosophila eye. EMBO J. 1996 Jul 15; 15(14):3684-92.
    View in: PubMed
  83. Zukerberg LR, Benedict WF, Arnold A, Dyson N, Harlow E, Harris NL. Expression of the retinoblastoma protein in low-grade B-cell lymphoma: relationship to cyclin D1. Blood. 1996 Jul 1; 88(1):268-76.
    View in: PubMed
  84. Cobrinik D, Lee MH, Hannon G, Mulligan G, Bronson RT, Dyson N, Harlow E, Beach D, Weinberg RA, Jacks T. Shared role of the pRB-related p130 and p107 proteins in limb development. Genes Dev. 1996 Jul 1; 10(13):1633-44.
    View in: PubMed
  85. Wu CL, Classon M, Dyson N, Harlow E. Expression of dominant-negative mutant DP-1 blocks cell cycle progression in G1. Mol Cell Biol. 1996 Jul; 16(7):3698-706.
    View in: PubMed
  86. Lee MH, Williams BO, Mulligan G, Mukai S, Bronson RT, Dyson N, Harlow E, Jacks T. Targeted disruption of p107: functional overlap between p107 and Rb. Genes Dev. 1996 Jul 1; 10(13):1621-32.
    View in: PubMed
  87. Yamasaki L, Jacks T, Bronson R, Goillot E, Harlow E, Dyson NJ. Tumor induction and tissue atrophy in mice lacking E2F-1. Cell. 1996 May 17; 85(4):537-48.
    View in: PubMed
  88. Du W, Vidal M, Xie JE, Dyson N. RBF, a novel RB-related gene that regulates E2F activity and interacts with cyclin E in Drosophila. Genes Dev. 1996 May 15; 10(10):1206-18.
    View in: PubMed
  89. Duronio RJ, O'Farrell PH, Xie JE, Brook A, Dyson N. The transcription factor E2F is required for S phase during Drosophila embryogenesis. Genes Dev. 1995 Jun 15; 9(12):1445-55.
    View in: PubMed
  90. Dynlacht BD, Brook A, Dembski M, Yenush L, Dyson N. DNA-binding and trans-activation properties of Drosophila E2F and DP proteins. Proc Natl Acad Sci U S A. 1994 Jul 5; 91(14):6359-63.
    View in: PubMed
  91. Zhu L, Enders GH, Wu CL, Starz MA, Moberg KH, Lees JA, Dyson N, Harlow E. Growth suppression by members of the retinoblastoma protein family. Cold Spring Harb Symp Quant Biol. 1994; 59:75-84.
    View in: PubMed
  92. Dyson N. pRB, p107 and the regulation of the E2F transcription factor. J Cell Sci Suppl. 1994; 18:81-7.
    View in: PubMed
  93. Lees JA, Saito M, Vidal M, Valentine M, Look T, Harlow E, Dyson N, Helin K. The retinoblastoma protein binds to a family of E2F transcription factors. Mol Cell Biol. 1993 Dec; 13(12):7813-25.
    View in: PubMed
  94. Dyson N, Dembski M, Fattaey A, Ngwu C, Ewen M, Helin K. Analysis of p107-associated proteins: p107 associates with a form of E2F that differs from pRB-associated E2F-1. J Virol. 1993 Dec; 67(12):7641-7.
    View in: PubMed
  95. Fattaey AR, Helin K, Dembski MS, Dyson N, Harlow E, Vuocolo GA, Hanobik MG, Haskell KM, Oliff A, Defeo-Jones D, et al. Characterization of the retinoblastoma binding proteins RBP1 and RBP2. Oncogene. 1993 Nov; 8(11):3149-56.
    View in: PubMed
  96. Zhu L, van den Heuvel S, Helin K, Fattaey A, Ewen M, Livingston D, Dyson N, Harlow E. Inhibition of cell proliferation by p107, a relative of the retinoblastoma protein. Genes Dev. 1993 Jul; 7(7A):1111-25.
    View in: PubMed
  97. Dyson N, Guida P, Münger K, Harlow E. Homologous sequences in adenovirus E1A and human papillomavirus E7 proteins mediate interaction with the same set of cellular proteins. J Virol. 1992 Dec; 66(12):6893-902.
    View in: PubMed
  98. Helin K, Lees JA, Vidal M, Dyson N, Harlow E, Fattaey A. A cDNA encoding a pRB-binding protein with properties of the transcription factor E2F. Cell. 1992 Jul 24; 70(2):337-50.
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  99. Dyson N, Guida P, McCall C, Harlow E. Adenovirus E1A makes two distinct contacts with the retinoblastoma protein. J Virol. 1992 Jul; 66(7):4606-11.
    View in: PubMed
  100. Cao L, Faha B, Dembski M, Tsai LH, Harlow E, Dyson N. Independent binding of the retinoblastoma protein and p107 to the transcription factor E2F. Nature. 1992 Jan 9; 355(6356):176-9.
    View in: PubMed
  101. Dyson N, Harlow E. Adenovirus E1A targets key regulators of cell proliferation. Cancer Surv. 1992; 12:161-95.
    View in: PubMed
  102. Rustgi AK, Dyson N, Bernards R. Amino-terminal domains of c-myc and N-myc proteins mediate binding to the retinoblastoma gene product. Nature. 1991 Aug 8; 352(6335):541-4.
    View in: PubMed
  103. Larose A, Dyson N, Sullivan M, Harlow E, Bastin M. Polyomavirus large T mutants affected in retinoblastoma protein binding are defective in immortalization. J Virol. 1991 May; 65(5):2308-13.
    View in: PubMed
  104. Rustgi AK, Dyson N, Hill D, Bernards R. The c-myc oncoprotein forms a specific complex with the product of the retinoblastoma gene. Cold Spring Harb Symp Quant Biol. 1991; 56:163-7.
    View in: PubMed
  105. Hu QJ, Dyson N, Harlow E. The regions of the retinoblastoma protein needed for binding to adenovirus E1A or SV40 large T antigen are common sites for mutations. EMBO J. 1990 Apr; 9(4):1147-55.
    View in: PubMed
  106. Dyson N, Bernards R, Friend SH, Gooding LR, Hassell JA, Major EO, Pipas JM, Vandyke T, Harlow E. Large T antigens of many polyomaviruses are able to form complexes with the retinoblastoma protein. J Virol. 1990 Mar; 64(3):1353-6.
    View in: PubMed
  107. Buchkovich K, Dyson N, Whyte P, Harlow E. Cellular proteins that are targets for transformation by DNA tumour viruses. Ciba Found Symp. 1990; 150:262-71; discussion 271-8.
    View in: PubMed
  108. Münger K, Werness BA, Dyson N, Phelps WC, Harlow E, Howley PM. Complex formation of human papillomavirus E7 proteins with the retinoblastoma tumor suppressor gene product. EMBO J. 1989 Dec 20; 8(13):4099-105.
    View in: PubMed
  109. Dyson N, Buchkovich K, Whyte P, Harlow E. The cellular 107K protein that binds to adenovirus E1A also associates with the large T antigens of SV40 and JC virus. Cell. 1989 Jul 28; 58(2):249-55.
    View in: PubMed
  110. Dyson N, Howley PM, Münger K, Harlow E. The human papilloma virus-16 E7 oncoprotein is able to bind to the retinoblastoma gene product. Science. 1989 Feb 17; 243(4893):934-7.
    View in: PubMed
  111. Dyson N, Buchkovich K, Whyte P, Harlow E. Cellular proteins that are targetted by DNA tumor viruses for transformation. Princess Takamatsu Symp. 1989; 20:191-8.
    View in: PubMed
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