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Grewo Lim, Ph.D.

TitleInstructor in Anaesthesia
InstitutionMassachusetts General Hospital
DepartmentAnaesthesia
AddressMassachusetts General Hospital
Anesthesia
55 Fruit St
Boston MA 02114
Phone617/724-9198
Fax617/726-6337

 Bibliographic 
 selected publications
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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  1. Wang S, Song L, Tan Y, Ma Y, Tian Y, Jin X, Lim G, Zhang S, Chen L, Mao J. A Functional Relationship Between Trigeminal Astroglial Activation and NR1 Expression in a Rat Model of Temporomandibular Joint Inflammation. Pain Med. 2012 Dec; 13(12):1590-600.
    View in: PubMed
  2. Wang S, Tian Y, Song L, Lim G, Tan Y, You Z, Chen L, Mao J. Exacerbated mechanical hyperalgesia in rats with genetically predisposed depressive behavior: Role of melatonin and NMDA receptors. Pain. 2012 Dec; 153(12):2448-57.
    View in: PubMed
  3. Kim H, Chen L, Lim G, Sung B, Wang S, McCabe MF, Rusanescu G, Yang L, Tian Y, Mao J. Brain indoleamine 2,3-dioxygenase contributes to the comorbidity of pain and depression. J Clin Invest. 2012 Aug 1; 122(8):2940-54.
    View in: PubMed
  4. Tian Y, Wang S, Ma Y, Lim G, Kim H, Mao J. Leptin enhances NMDA-induced spinal excitation in rats: A functional link between adipocytokine and neuropathic pain. Pain. 2011 Jun; 152(6):1263-71.
    View in: PubMed
  5. Chou CW, Wong GT, Lim G, McCabe MF, Wang S, Irwin MG, Mao J. Peripheral nerve injury alters the expression of NF-?B in the rat's hippocampus. Brain Res. 2011 Mar 10; 1378:66-71.
    View in: PubMed
  6. Chou CW, Wong GT, Lim G, Wang S, Irwin MG, Mao J. Spatiotemporal pattern of concurrent spinal and supraspinal NF-?B expression after peripheral nerve injury. J Pain. 2011 Jan; 12(1):13-21.
    View in: PubMed
  7. Wang S, Zhang L, Lim G, Sung B, Tian Y, Chou CW, Hernstadt H, Rusanescu G, Ma Y, Mao J. A combined effect of dextromethorphan and melatonin on neuropathic pain behavior in rats. Brain Res. 2009 Sep 8; 1288:42-9.
    View in: PubMed
  8. Hernstadt H, Wang S, Lim G, Mao J. Spinal translocator protein (TSPO) modulates pain behavior in rats with CFA-induced monoarthritis. Brain Res. 2009 Aug 25; 1286:42-52.
    View in: PubMed
  9. Lim G, Wang S, Zhang Y, Tian Y, Mao J. Spinal leptin contributes to the pathogenesis of neuropathic pain in rodents. J Clin Invest. 2009 Feb; 119(2):295-304.
    View in: PubMed
  10. Wang S, Lim G, Mao J, Sung B, Mao J. Regulation of the trigeminal NR1 subunit expression induced by inflammation of the temporomandibular joint region in rats. Pain. 2009 Jan; 141(1-2):97-103.
    View in: PubMed
  11. Yang L, Wang S, Lim G, Sung B, Zeng Q, Mao J. Inhibition of the ubiquitin-proteasome activity prevents glutamate transporter degradation and morphine tolerance. Pain. 2008 Dec; 140(3):472-8.
    View in: PubMed
  12. Yang L, Wang S, Sung B, Lim G, Mao J. Morphine induces ubiquitin-proteasome activity and glutamate transporter degradation. J Biol Chem. 2008 Aug 1; 283(31):21703-13.
    View in: PubMed
  13. Zeng Q, Wang S, Lim G, Yang L, Mao J, Sung B, Chang Y, Lim JA, Guo G, Mao J. Exacerbated mechanical allodynia in rats with depression-like behavior. Brain Res. 2008 Mar 20; 1200:27-38.
    View in: PubMed
  14. Gu X, Yang L, Wang S, Sung B, Lim G, Mao J, Zeng Q, Yang C, Mao J. A rat model of radicular pain induced by chronic compression of lumbar dorsal root ganglion with SURGIFLO. Anesthesiology. 2008 Jan; 108(1):113-21.
    View in: PubMed
  15. Gu X, Wang S, Yang L, Sung B, Lim G, Mao J, Zeng Q, Chang Y, Mao J. Time-dependent effect of epidural steroid on pain behavior induced by chronic compression of dorsal root ganglion in rats. Brain Res. 2007 Oct 12; 1174:39-46.
    View in: PubMed
  16. Sung B, Wang S, Zhou B, Lim G, Yang L, Zeng Q, Lim JA, Wang JD, Kang JX, Mao J. Altered spinal arachidonic acid turnover after peripheral nerve injury regulates regional glutamate concentration and neuropathic pain behaviors in rats. Pain. 2007 Sep; 131(1-2):121-31.
    View in: PubMed
  17. Wang S, Lim G, Mao J, Sung B, Yang L, Mao J. Central glucocorticoid receptors regulate the upregulation of spinal cannabinoid-1 receptors after peripheral nerve injury in rats. Pain. 2007 Sep; 131(1-2):96-105.
    View in: PubMed
  18. Lim J, Lim G, Sung B, Wang S, Mao J. Intrathecal midazolam regulates spinal AMPA receptor expression and function after nerve injury in rats. Brain Res. 2006 Dec 6; 1123(1):80-8.
    View in: PubMed
  19. Wang S, Lim G, Yang L, Sung B, Mao J. Downregulation of spinal glutamate transporter EAAC1 following nerve injury is regulated by central glucocorticoid receptors in rats. Pain. 2006 Jan; 120(1-2):78-85.
    View in: PubMed
  20. Lim G, Wang S, Lim JA, Mao J. Activity of adenylyl cyclase and protein kinase A contributes to morphine-induced spinal apoptosis. Neurosci Lett. 2005 Dec 2; 389(2):104-8.
    View in: PubMed
  21. Lim G, Wang S, Zeng Q, Sung B, Yang L, Mao J. Expression of spinal NMDA receptor and PKCgamma after chronic morphine is regulated by spinal glucocorticoid receptor. J Neurosci. 2005 Nov 30; 25(48):11145-54.
    View in: PubMed
  22. Lim G, Wang S, Mao J. Central glucocorticoid receptors modulate the expression of spinal cannabinoid receptors induced by chronic morphine exposure. Brain Res. 2005 Oct 12; 1059(1):20-7.
    View in: PubMed
  23. Wang S, Lim G, Yang L, Zeng Q, Sung B, Jeevendra Martyn JA, Mao J. A rat model of unilateral hindpaw burn injury: slowly developing rightwards shift of the morphine dose-response curve. Pain. 2005 Jul; 116(1-2):87-95.
    View in: PubMed
  24. Lim G, Wang S, Zeng Q, Sung B, Mao J. Spinal glucocorticoid receptors contribute to the development of morphine tolerance in rats. Anesthesiology. 2005 Apr; 102(4):832-7.
    View in: PubMed
  25. Wang S, Lim G, Zeng Q, Sung B, Yang L, Mao J. Central glucocorticoid receptors modulate the expression and function of spinal NMDA receptors after peripheral nerve injury. J Neurosci. 2005 Jan 12; 25(2):488-95.
    View in: PubMed
  26. Lim G, Wang S, Zeng Q, Sung B, Mao J. Evidence for a long-term influence on morphine tolerance after previous morphine exposure: role of neuronal glucocorticoid receptors. Pain. 2005 Mar; 114(1-2):81-92.
    View in: PubMed
  27. Lim G, Wang S, Mao J. cAMP and protein kinase A contribute to the downregulation of spinal glutamate transporters after chronic morphine. Neurosci Lett. 2005 Mar 7; 376(1):9-13.
    View in: PubMed
  28. Wang S, Lim G, Zeng Q, Sung B, Ai Y, Guo G, Yang L, Mao J. Expression of central glucocorticoid receptors after peripheral nerve injury contributes to neuropathic pain behaviors in rats. J Neurosci. 2004 Sep 29; 24(39):8595-605.
    View in: PubMed
  29. Lim G, Sung B, Ji RR, Mao J. Upregulation of spinal cannabinoid-1-receptors following nerve injury enhances the effects of Win 55,212-2 on neuropathic pain behaviors in rats. Pain. 2003 Sep; 105(1-2):275-83.
    View in: PubMed
  30. Sung B, Lim G, Mao J. Altered expression and uptake activity of spinal glutamate transporters after nerve injury contribute to the pathogenesis of neuropathic pain in rats. J Neurosci. 2003 Apr 1; 23(7):2899-910.
    View in: PubMed
  31. Mao J, Sung B, Ji RR, Lim G. Chronic morphine induces downregulation of spinal glutamate transporters: implications in morphine tolerance and abnormal pain sensitivity. J Neurosci. 2002 Sep 15; 22(18):8312-23.
    View in: PubMed
  32. Mao J, Sung B, Ji RR, Lim G. Neuronal apoptosis associated with morphine tolerance: evidence for an opioid-induced neurotoxic mechanism. J Neurosci. 2002 Sep 1; 22(17):7650-61.
    View in: PubMed
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