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Jeffrey Heier, M.D.

TitleClinical Instructor in Ophthalmology
InstitutionMassachusetts Eye and Ear Infirmary
DepartmentOphthalmology
AddressOphthalmic Consultants of Bos.
Ste. 600
50 Staniford Street
Boston MA 02114
Phone617/367-4800

 Mentoring 
 completed student projects
Efficacy of Ketorolac Tromethamine 0.3% vs. Control in Combination With Prednisolone Acetate 1.0% in the Prophylaxis of Cystoid Macular Edema After Retinal Detachment Repair
Part Time, 11/01/01 - 06/01/02

 Bibliographic 
 selected publications
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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  1. Brown DM, Heier JS, Clark WL, Boyer DS, Vitti R, Berliner AJ, Zeitz O, Sandbrink R, Zhu X, Haller JA. Intravitreal Aflibercept Injection for Macular Edema Secondary to Central Retinal Vein Occlusion: 1-Year Results From the Phase 3 COPERNICUS Study. Am J Ophthalmol. 2013 Mar; 155(3):429-437.e7.
    View in: PubMed
  2. Campochiaro PA, Channa R, Berger BB, Heier JS, Brown DM, Fiedler U, Hepp J, Stumpp MT. Treatment of Diabetic Macular Edema With a Designed Ankyrin Repeat Protein That Binds Vascular Endothelial Growth Factor: A Phase I/II Study. Am J Ophthalmol. 2013 Apr; 155(4):697-704.e2.
    View in: PubMed
  3. Heier JS, Brown DM, Chong V, Korobelnik JF, Kaiser PK, Nguyen QD, Kirchhof B, Ho A, Ogura Y, Yancopoulos GD, Stahl N, Vitti R, Berliner AJ, Soo Y, Anderesi M, Groetzbach G, Sommerauer B, Sandbrink R, Simader C, Schmidt-Erfurth U. Intravitreal Aflibercept (VEGF Trap-Eye) in Wet Age-related Macular Degeneration. Ophthalmology. 2012 Dec; 119(12):2537-48.
    View in: PubMed
  4. Heier J. Ask the doctor. I have been diagnosed with macular degeneration and cataracts in both eyes. Could cataract surgery worsen my macular degeneration? Harv Health Lett. 2012 May; 37(7):8.
    View in: PubMed
  5. Do DV, Nguyen QD, Boyer D, Schmidt-Erfurth U, Brown DM, Vitti R, Berliner AJ, Gao B, Zeitz O, Ruckert R, Schmelter T, Sandbrink R, Heier JS. One-year outcomes of the DA VINCI Study of VEGF Trap-Eye in eyes with diabetic macular edema. Ophthalmology. 2012 Aug; 119(8):1658-65.
    View in: PubMed
  6. Boyer D, Heier J, Brown DM, Clark WL, Vitti R, Berliner AJ, Groetzbach G, Zeitz O, Sandbrink R, Zhu X, Beckmann K, Haller JA. Vascular endothelial growth factor Trap-Eye for macular edema secondary to central retinal vein occlusion: six-month results of the phase 3 COPERNICUS study. Ophthalmology. 2012 May; 119(5):1024-32.
    View in: PubMed
  7. Heier JS, Campochiaro PA, Yau L, Li Z, Saroj N, Rubio RG, Lai P. Ranibizumab for Macular Edema Due to Retinal Vein Occlusions: Long-term Follow-up in the HORIZON Trial. Ophthalmology. 2012 Apr; 119(4):802-9.
    View in: PubMed
  8. Do DV, Gower EW, Cassard SD, Boyer D, Bressler NM, Bressler SB, Heier JS, Jefferys JL, Singerman LJ, Solomon SD. Detection of New-Onset Choroidal Neovascularization Using Optical Coherence Tomography: The AMD DOC Study. Ophthalmology. 2012 Apr; 119(4):771-8.
    View in: PubMed
  9. Chiang A, Kaiser RS, Avery RL, Dugel PU, Eliott D, Shah SP, Heier J, Duker J, Hu AY, Schwartz SD, Scott IU, Pollack JS, Faia LJ, Williams GA. Endophthalmitis in microincision vitrectomy: outcomes of gas-filled eyes. Retina. 2011 Sep; 31(8):1513-7.
    View in: PubMed
  10. Haller JA, Bandello F, Belfort R, Blumenkranz MS, Gillies M, Heier J, Loewenstein A, Yoon YH, Jiao J, Li XY, Whitcup SM, Li J. Dexamethasone intravitreal implant in patients with macular edema related to branch or central retinal vein occlusion twelve-month study results. Ophthalmology. 2011 Dec; 118(12):2453-60.
    View in: PubMed
  11. Brown DM, Heier JS, Ciulla T, Benz M, Abraham P, Yancopoulos G, Stahl N, Ingerman A, Vitti R, Berliner AJ, Yang K, Nguyen QD. Primary endpoint results of a phase II study of vascular endothelial growth factor trap-eye in wet age-related macular degeneration. Ophthalmology. 2011 Jun; 118(6):1089-97.
    View in: PubMed
  12. Heier JS, Boyer D, Nguyen QD, Marcus D, Roth DB, Yancopoulos G, Stahl N, Ingerman A, Vitti R, Berliner AJ, Yang K, Brown DM. The 1-year results of CLEAR-IT 2, a phase 2 study of vascular endothelial growth factor trap-eye dosed as-needed after 12-week fixed dosing. Ophthalmology. 2011 Jun; 118(6):1098-106.
    View in: PubMed
  13. Do DV, Schmidt-Erfurth U, Gonzalez VH, Gordon CM, Tolentino M, Berliner AJ, Vitti R, Rückert R, Sandbrink R, Stein D, Yang K, Beckmann K, Heier JS. The DA VINCI Study: phase 2 primary results of VEGF Trap-Eye in patients with diabetic macular edema. Ophthalmology. 2011 Sep; 118(9):1819-26.
    View in: PubMed
  14. Heier JS. Ask the doctor. I think I may have cataracts. I heard somewhere that they need to be ripe before I get surgery. Is that true? Harv Health Lett. 2011 May; 36(7):3.
    View in: PubMed
  15. Zhang K, Hopkins JJ, Heier JS, Birch DG, Halperin LS, Albini TA, Brown DM, Jaffe GJ, Tao W, Williams GA. Ciliary neurotrophic factor delivered by encapsulated cell intraocular implants for treatment of geographic atrophy in age-related macular degeneration. Proc Natl Acad Sci U S A. 2011 Apr 12; 108(15):6241-5.
    View in: PubMed
  16. Heier JS, Brown D, Ciulla T, Abraham P, Bankert JM, Chong S, Daniel PE, Kim IK. Ranibizumab for choroidal neovascularization secondary to causes other than age-related macular degeneration: a phase I clinical trial. Ophthalmology. 2011 Jan; 118(1):111-8.
    View in: PubMed
  17. Shingleton BJ, Marvin AC, Heier JS, O'Donoghue MW, Laul A, Wolff B, Rowland A. Pseudoexfoliation: High risk factors for zonule weakness and concurrent vitrectomy during phacoemulsification. J Cataract Refract Surg. 2010 Aug; 36(8):1261-9.
    View in: PubMed
  18. Morley MG, Nguyen JK, Heier JS, Shingleton BJ, Pasternak JF, Bower KS. Blast eye injuries: a review for first responders. Disaster Med Public Health Prep. 2010 Jun; 4(2):154-60.
    View in: PubMed
  19. Heier JS. By the way, doctor. My 78-year-old husband has wet macular degeneration. He is being treated with a drug called Avastin. Is that a good choice? Harv Health Lett. 2010 May; 35(7):6.
    View in: PubMed
  20. Haller JA, Bandello F, Belfort R, Blumenkranz MS, Gillies M, Heier J, Loewenstein A, Yoon YH, Jacques ML, Jiao J, Li XY, Whitcup SM. Randomized, sham-controlled trial of dexamethasone intravitreal implant in patients with macular edema due to retinal vein occlusion. Ophthalmology. 2010 Jun; 117(6):1134-1146.e3.
    View in: PubMed
  21. Campochiaro PA, Heier JS, Feiner L, Gray S, Saroj N, Rundle AC, Murahashi WY, Rubio RG. Ranibizumab for macular edema following branch retinal vein occlusion: six-month primary end point results of a phase III study. Ophthalmology. 2010 Jun; 117(6):1102-1112.e1.
    View in: PubMed
  22. Zahn G, Volk K, Lewis GP, Vossmeyer D, Stragies R, Heier JS, Daniel PE, Adamis AP, Chapin EA, Fisher SK, Holz FG, Löffler KU, Knolle J. Assessment of the integrin alpha5beta1 antagonist JSM6427 in proliferative vitreoretinopathy using in vitro assays and a rabbit model of retinal detachment. Invest Ophthalmol Vis Sci. 2010 Feb; 51(2):1028-35.
    View in: PubMed
  23. Heier JS, Awh CC, Busbee BG, Waterbury LD, Daniel P, Stoller GL, Cleary TS. Vitreous nonsteroidal antiinflammatory drug concentrations and prostaglandin E2 levels in vitrectomy patients treated with ketorolac 0.4%, bromfenac 0.09%, and nepafenac 0.1%. Retina. 2009 Oct; 29(9):1310-3.
    View in: PubMed
  24. Boyer DS, Heier JS, Brown DM, Francom SF, Ianchulev T, Rubio RG. A Phase IIIb study to evaluate the safety of ranibizumab in subjects with neovascular age-related macular degeneration. Ophthalmology. 2009 Sep; 116(9):1731-9.
    View in: PubMed
  25. Ahmad FK, Morley MG, Berry A, Wiegand TW, Heier JS, Morley EF, Sanguansak T, Topping TM, Frederick AR, Sang DN, Hughes MS, Cleary TS. Effects of ranibizumab on exudative disciform scars. Ophthalmic Surg Lasers Imaging. 2009 Jul-Aug; 40(4):366-72.
    View in: PubMed
  26. Heier JS. Pathology beyond neovascularization: new targets in age-related macular degeneration. Retina. 2009 Jun; 29(6 Suppl):S39-41.
    View in: PubMed
  27. Brown DM, Michels M, Kaiser PK, Heier JS, Sy JP, Ianchulev T. Ranibizumab versus verteporfin photodynamic therapy for neovascular age-related macular degeneration: Two-year results of the ANCHOR study. Ophthalmology. 2009 Jan; 116(1):57-65.e5.
    View in: PubMed
  28. Fintak DR, Shah GK, Blinder KJ, Regillo CD, Pollack J, Heier JS, Hollands H, Sharma S. Incidence of endophthalmitis related to intravitreal injection of bevacizumab and ranibizumab. Retina. 2008 Nov-Dec; 28(10):1395-9.
    View in: PubMed
  29. Hudson HL, Stulting RD, Heier JS, Lane SS, Chang DF, Singerman LJ, Bradford CA, Leonard RE. Implantable telescope for end-stage age-related macular degeneration: long-term visual acuity and safety outcomes. Am J Ophthalmol. 2008 Nov; 146(5):664-673.
    View in: PubMed
  30. Wittpenn JR, Silverstein S, Heier J, Kenyon KR, Hunkeler JD, Earl M. A randomized, masked comparison of topical ketorolac 0.4% plus steroid vs steroid alone in low-risk cataract surgery patients. Am J Ophthalmol. 2008 Oct; 146(4):554-560.
    View in: PubMed
  31. Heier JS, Boyer DS, Ciulla TA, Ferrone PJ, Jumper JM, Gentile RC, Kotlovker D, Chung CY, Kim RY. Ranibizumab combined with verteporfin photodynamic therapy in neovascular age-related macular degeneration: year 1 results of the FOCUS Study. Arch Ophthalmol. 2006 Nov; 124(11):1532-42.
    View in: PubMed
  32. Subramanian ML, Heier JS, Esrick E, Devaiah AK, Topping TM, Frederick AR, Morley MG. Preoperative visual acuity as a prognostic indicator for laser treatment of macular edema due to branch retinal vein occlusion. Ophthalmic Surg Lasers Imaging. 2006 Nov-Dec; 37(6):462-7.
    View in: PubMed
  33. Rosenfeld PJ, Brown DM, Heier JS, Boyer DS, Kaiser PK, Chung CY, Kim RY. Ranibizumab for neovascular age-related macular degeneration. N Engl J Med. 2006 Oct 5; 355(14):1419-31.
    View in: PubMed
  34. Brown DM, Kaiser PK, Michels M, Soubrane G, Heier JS, Kim RY, Sy JP, Schneider S. Ranibizumab versus verteporfin for neovascular age-related macular degeneration. N Engl J Med. 2006 Oct 5; 355(14):1432-44.
    View in: PubMed
  35. Chun DW, Heier JS, Topping TM, Duker JS, Bankert JM. A pilot study of multiple intravitreal injections of ranibizumab in patients with center-involving clinically significant diabetic macular edema. Ophthalmology. 2006 Oct; 113(10):1706-12.
    View in: PubMed
  36. Hudson HL, Lane SS, Heier JS, Stulting RD, Singerman L, Lichter PR, Sternberg P, Chang DF. Implantable miniature telescope for the treatment of visual acuity loss resulting from end-stage age-related macular degeneration: 1-year results. Ophthalmology. 2006 Nov; 113(11):1987-2001.
    View in: PubMed
  37. Rosenfeld PJ, Heier JS, Hantsbarger G, Shams N. Tolerability and efficacy of multiple escalating doses of ranibizumab (Lucentis) for neovascular age-related macular degeneration. Ophthalmology. 2006 Apr; 113(4):623.e1.
    View in: PubMed
  38. Heier JS, Antoszyk AN, Pavan PR, Leff SR, Rosenfeld PJ, Ciulla TA, Dreyer RF, Gentile RC, Sy JP, Hantsbarger G, Shams N. Ranibizumab for treatment of neovascular age-related macular degeneration: a phase I/II multicenter, controlled, multidose study. Ophthalmology. 2006 Apr; 113(4):633.e1-4.
    View in: PubMed
  39. Chun DW, Heier JS, Raizman MB. Visual prosthetic device for bilateral end-stage macular degeneration. Expert Rev Med Devices. 2005 Nov; 2(6):657-65.
    View in: PubMed
  40. Alster Y, Bressler NM, Bressler SB, Brimacombe JA, Crompton RM, Duh YJ, Gabel VP, Heier JS, Ip MS, Loewenstein A, Packo KH, Stur M, Toaff T. Preferential Hyperacuity Perimeter (PreView PHP) for detecting choroidal neovascularization study. Ophthalmology. 2005 Oct; 112(10):1758-65.
    View in: PubMed
  41. Esrick E, Subramanian ML, Heier JS, Devaiah AK, Topping TM, Frederick AR, Morley MG. Multiple laser treatments for macular edema attributable to branch retinal vein occlusion. Am J Ophthalmol. 2005 Apr; 139(4):653-7.
    View in: PubMed
  42. Kim RW, Heier JS. Innovative treatments for exudative age-related macular degeneration. Int Ophthalmol Clin. 2004; 44(4):41-50.
    View in: PubMed
  43. Heier JS, Topping TM, Baumann W, Dirks MS, Chern S. Ketorolac versus prednisolone versus combination therapy in the treatment of acute pseudophakic cystoid macular edema. Ophthalmology. 2000 Nov; 107(11):2034-8;discussion 2039.
    View in: PubMed
  44. McColgin AZ, Heier JS. Control of intraocular inflammation associated with cataract surgery. Curr Opin Ophthalmol. 2000 Feb; 11(1):3-6.
    View in: PubMed
  45. Durand ML, Heier JS. Endophthalmitis. Curr Clin Top Infect Dis. 2000; 20:271-97.
    View in: PubMed
  46. Heier J, Cheetham JK, Degryse R, Dirks MS, Caldwell DR, Silverstone DE, Rosenthal A. Ketorolac tromethamine 0.5% ophthalmic solution in the treatment of moderate to severe ocular inflammation after cataract surgery: a randomized, vehicle-controlled clinical trial. Am J Ophthalmol. 1999 Mar; 127(3):253-9.
    View in: PubMed
  47. Heier JS, Topping TM, Frederick AR, Morley MG, Millay R, Pesavento RD. Visual and surgical outcomes of retinal detachment following macular hole repair. Retina. 1999; 19(2):110-5.
    View in: PubMed
  48. Postel EA, Pulido JS, Byrnes GA, Heier J, Waterhouse W, Han DP, Mieler WF, Guse C, Wipplinger W. Long-term follow-up of iatrogenic phototoxicity. Arch Ophthalmol. 1998 Jun; 116(6):753-7.
    View in: PubMed
  49. Heier JS, Steinert RF, Frederick AR. Cystoid macular edema associated with latanoprost use. Arch Ophthalmol. 1998 May; 116(5):680-2.
    View in: PubMed
  50. Heier JS, Gardner TA, Hawes MJ, McGuire KA, Walton WT, Stock J. Proptosis as the initial presentation of fungal sinusitis in immunocompetent patients. Ophthalmology. 1995 May; 102(5):713-7.
    View in: PubMed
  51. Heier JS, Walton WT, Enzenauer RW, Rice W, Tuman D. Wound strength comparison of a 5.1-millimeter no-stitch with a 7.0-millimeter sutured incision in human cadaver globes. Ophthalmic Surg. 1994 Nov-Dec; 25(10):685-7.
    View in: PubMed
  52. Heier JS, Dragoo RA, Enzenauer RW, Waterhouse WJ. Screening for ocular toxicity in asymptomatic patients treated with tamoxifen. Am J Ophthalmol. 1994 Jun 15; 117(6):772-5.
    View in: PubMed
  53. Mader TH, Aragones JV, Chandler AC, Hazlehurst JA, Heier J, Kingham JD, Stein E. Ocular and ocular adnexal injuries treated by United States military ophthalmologists during Operations Desert Shield and Desert Storm. Ophthalmology. 1993 Oct; 100(10):1462-7.
    View in: PubMed
  54. Heier JS, Enzenauer RW, Wintermeyer SF, Delaney M, LaPiana FP. Ocular injuries and diseases at a combat support hospital in support of Operations Desert Shield and Desert Storm. Arch Ophthalmol. 1993 Jun; 111(6):795-8.
    View in: PubMed
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