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Steven Alex Safren, Ph.D.

TitleProfessor of Psychology in the Department of Psychiatry
InstitutionMassachusetts General Hospital
DepartmentPsychiatry
AddressMassachusetts General Hospital
Behavioral Medicine, Psychiatry, 7th Floor
1 Bowdoin Sq
Boston MA 02114
Phone617/724-0817
Fax617/724-8690

 Biography 
 awards and honors
1998 - 1998Emerson Research Award (awarded to fellows)
2001 - 2001Award for Excellence in Teaching and Mentoring
2004 - 2004Award for Excellence in Teaching and Mentoring
2008 - 2008Distinguished Contribution to Education and Training Award
2008 - 2008Award for Excellence in Teaching and Mentoring
2010 - 2010A. Clifford Barger Excellence in Mentoring Award
2011 - 2011Award for Excellence in Teaching and Mentoring

 Overview 
 overview
Dr. Safren's focus is on cognitive behavioral intervention development, particularly in the areas of HIV and other chronic illnesses, as well as adult ADHD. Dr. Safren has over 160 professional publications inclusive of data-driven papers, reviews, chapters, commentaries, and books; and has been the PI or protocol chair of 9 NIH-funded grants in these areas. HIs work in HIV has been extended nationally and internationally, and he has regularly served as a reviewer for the National Institutes of Health's study sections that review grants related to behavioral aspects of HIV/AIDS. He has published treatment manuals for therapists working with adults with ADHD and working with individuals with depression that co-occurs with a chronic medical illness.


 Bibliographic 
 selected publications
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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  1. Blashill AJ, Wilson JM, O'Cleirigh CM, Mayer KH, Safren SA. Examining the Correspondence Between Relationship Identity and Actual Sexual Risk Behavior Among HIV-Positive Men Who Have Sex with Men. Arch Sex Behav. 2014 Jan; 43(1):129-37.
    View in: PubMed
  2. Hersch RK, Cook RF, Billings DW, Kaplan S, Murray D, Safren S, Goforth J, Spencer J. Test of a Web-Based Program to Improve Adherence to HIV Medications. AIDS Behav. 2013 Nov; 17(9):2963-76.
    View in: PubMed
  3. Blashill AJ, Mayer KH, Crane H, Magidson JF, Grasso C, Mathews WC, Saag MS, Safren SA. Physical Activity and Health Outcomes Among HIV-Infected Men Who Have Sex with Men: A Longitudinal Mediational Analysis. Ann Behav Med. 2013 Oct; 46(2):149-56.
    View in: PubMed
  4. Simoni JM, Wiebe JS, Sauceda JA, Huh D, Sanchez G, Longoria V, Andres Bedoya C, Safren SA. A Preliminary RCT of CBT-AD for Adherence and Depression Among HIV-Positive Latinos on the U.S.-Mexico Border: The Nuevo Día Study. AIDS Behav. 2013 Oct; 17(8):2816-29.
    View in: PubMed
  5. Tsai AC, Mimiaga MJ, Dilley JW, Hammer GP, Karasic DH, Charlebois ED, Sorensen JL, Safren SA, Bangsberg DR. Does Effective Depression Treatment Alone Reduce Secondary HIV Transmission Risk? Equivocal Findings from a Randomized Controlled Trial. AIDS Behav. 2013 Oct; 17(8):2765-72.
    View in: PubMed
  6. Knouse LE, Traeger L, O'Cleirigh C, Safren SA. Adult attention deficit hyperactivity disorder symptoms and five-factor model traits in a clinical sample: a structural equation modeling approach. J Nerv Ment Dis. 2013 Oct; 201(10):848-54.
    View in: PubMed
  7. Haberer JE, Baeten JM, Campbell J, Wangisi J, Katabira E, Ronald A, Tumwesigye E, Psaros C, Safren SA, Ware NC, Thomas KK, Donnell D, Krows M, Kidoguchi L, Celum C, Bangsberg DR. Adherence to Antiretroviral Prophylaxis for HIV Prevention: A Substudy Cohort within a Clinical Trial of Serodiscordant Couples in East Africa. PLoS Med. 2013 Sep; 10(9):e1001511.
    View in: PubMed
  8. Robbins GK, Testa MA, Su M, Safren SA, Morse G, Lammert S, Shafer RW, Reynolds NR, Chesney MA. Site Nurse-Initiated Adherence and Symptom Support Telephone Calls for HIV-Positive Individuals Starting Antiretroviral Therapy, ACTG 5031: Substudy of ACTG 384. HIV Clin Trials. 2013 Sep-Oct; 14(5):235-53.
    View in: PubMed
  9. Psaros C, O'Cleirigh C, Bullis JR, Markowitz SM, Safren SA. Variables on health-related quality of life among HIV-positive individuals with a history of intravenous drug use. J Psychoactive Drugs. 2013 Sep-Oct; 45(4):304-12.
    View in: PubMed
  10. Mimiaga MJ, Reisner SL, Grasso C, Crane HM, Safren SA, Kitahata MM, Schumacher JE, Mathews WC, Mayer KH. Substance use among HIV-infected patients engaged in primary care in the United States: findings from the Centers for AIDS Research Network of Integrated Clinical Systems cohort. Am J Public Health. 2013 Aug; 103(8):1457-67.
    View in: PubMed
  11. Baranoski AS, Meuser E, Hardy H, Closson EF, Mimiaga MJ, Safren SA, Virk P, Luk R, Skolnik PR, Kumar VS. Patient and provider perspectives on cellular phone-based technology to improve HIV treatment adherence. AIDS Care. 2014 Jan; 26(1):26-32.
    View in: PubMed
  12. O'Cleirigh C, Newcomb ME, Mayer KH, Skeer M, Traeger L, Safren SA. Moderate Levels of Depression Predict Sexual Transmission Risk in HIV-Infected MSM: A Longitudinal Analysis of Data From Six Sites Involved in a "Prevention for Positives" Study. AIDS Behav. 2013 Jun; 17(5):1764-9.
    View in: PubMed
  13. Blashill AJ, Mayer KH, Crane HM, Grasso C, Safren SA. Body Mass Index, Immune Status, and Virological Control in HIV-Infected Men Who Have Sex with Men. J Int Assoc Provid AIDS Care. 2013 Sep-Oct; 12(5):319-24.
    View in: PubMed
  14. Mimiaga MJ, Biello KB, Sivasubramanian M, Mayer KH, Anand VR, Safren SA. Psychosocial risk factors for HIV sexual risk among Indian men who have sex with men. AIDS Care. 2013 Sep; 25(9):1109-13.
    View in: PubMed
  15. Wade Taylor S, O'Cleirigh C, Mayer KH, Safren SA. HIV-infected men who have sex with men who engage in very high levels of transmission risk behaviors: Establishing a context for novel prevention interventions. Psychol Health Med. 2013 Oct; 18(5):576-87.
    View in: PubMed
  16. Gonzalez A, Mimiaga MJ, Israel J, Andres Bedoya C, Safren SA. Substance Use Predictors of Poor Medication Adherence: The Role of Substance Use Coping Among HIV-Infected Patients in Opioid Dependence Treatment. AIDS Behav. 2013 Jan; 17(1):168-73.
    View in: PubMed
  17. McHugh RK, Murray HW, Hearon BA, Pratt EM, Pollack MH, Safren SA, Otto MW. Predictors of dropout from psychosocial treatment in opioid-dependent outpatients. Am J Addict. 2013 Jan; 22(1):18-22.
    View in: PubMed
  18. Feldman BJ, Fredericksen RJ, Crane PK, Safren SA, Mugavero MJ, Willig JH, Simoni JM, Wilson IB, Saag MS, Kitahata MM, Crane HM. Evaluation of the Single-Item Self-Rating Adherence Scale for Use in Routine Clinical Care of People Living with HIV. AIDS Behav. 2013 Jan; 17(1):307-18.
    View in: PubMed
  19. Thomas B, Mimiaga MJ, Mayer KH, Closson EF, Johnson CV, Menon S, Mani J, Vijaylakshmi R, Dilip M, Betancourt T, Safren SA. Ensuring It Works: A Community-Based Approach to HIV Prevention Intervention Development for Men Who Have Sex with Men in Chennai, India. AIDS Educ Prev. 2012 Dec; 24(6):483-99.
    View in: PubMed
  20. Psaros C, Barinas J, Robbins GK, Bedoya CA, Safren SA, Park ER. Intimacy and Sexual Decision Making: Exploring the Perspective of HIV Positive Women Over 50. AIDS Patient Care STDS. 2012 Dec; 26(12):755-60.
    View in: PubMed
  21. Gonzalez JS, Schneider HE, Wexler DJ, Psaros C, Delahanty LM, Cagliero E, Safren SA. Validity of medication adherence self-reports in adults with type 2 diabetes. Diabetes Care. 2013 Apr; 36(4):831-7.
    View in: PubMed
  22. Blashill AJ, O'Cleirigh C, Mayer KH, Goshe BM, Safren SA. Body Mass Index, Depression and Sexual Transmission Risk Behaviors Among HIV-Positive MSM. AIDS Behav. 2012 Nov; 16(8):2251-6.
    View in: PubMed
  23. Mimiaga MJ, Reisner SL, Pantalone DW, O'Cleirigh C, Mayer KH, Safren SA. A Pilot Trial of Integrated Behavioral Activation and Sexual Risk Reduction Counseling for HIV-Uninfected Men Who Have Sex with Men Abusing Crystal Methamphetamine. AIDS Patient Care STDS. 2012 Nov; 26(11):681-93.
    View in: PubMed
  24. Blashill AJ, Gordon JR, Safren SA. Appearance concerns and psychological distress among HIV-infected individuals with injection drug use histories: prospective analyses. AIDS Patient Care STDS. 2012 Sep; 26(9):557-61.
    View in: PubMed
  25. Safren SA, O'Cleirigh CM, Skeer M, Elsesser SA, Mayer KH. Project enhance: A randomized controlled trial of an individualized HIV prevention intervention for HIV-infected men who have sex with men conducted in a primary care setting. Health Psychol. 2013 Feb; 32(2):171-9.
    View in: PubMed
  26. McHugh RK, Weitzman M, Safren SA, Murray HW, Pollack MH, Otto MW. Sexual HIV risk behaviors in a treatment-refractory opioid-dependent sample. J Psychoactive Drugs. 2012 Jul-Aug; 44(3):237-42.
    View in: PubMed
  27. Greer JA, Traeger L, Bemis H, Solis J, Hendriksen ES, Park ER, Pirl WF, Temel JS, Prigerson HG, Safren SA. A pilot randomized controlled trial of brief cognitive-behavioral therapy for anxiety in patients with terminal cancer. Oncologist. 2012; 17(10):1337-45.
    View in: PubMed
  28. Safren SA, O'Cleirigh CM, Bullis JR, Otto MW, Stein MD, Pollack MH. Cognitive behavioral therapy for adherence and depression (CBT-AD) in HIV-infected injection drug users: a randomized controlled trial. J Consult Clin Psychol. 2012 Jun; 80(3):404-15.
    View in: PubMed
  29. Thomas B, Mimiaga MJ, Mayer KH, Perry NS, Swaminathan S, Safren SA. The influence of stigma on HIV risk behavior among men who have sex with men in Chennai, India. AIDS Care. 2012 Nov; 24(11):1401-6.
    View in: PubMed
  30. Ware NC, Wyatt MA, Haberer JE, Baeten JM, Kintu A, Psaros C, Safren S, Tumwesigye E, Celum CL, Bangsberg DR. What's love got to do with it? Explaining adherence to oral antiretroviral pre-exposure prophylaxis for HIV-serodiscordant couples. J Acquir Immune Defic Syndr. 2012 Apr 15; 59(5):463-8.
    View in: PubMed
  31. Bedoya CA, Mimiaga MJ, Beauchamp G, Donnell D, Mayer KH, Safren SA. Predictors of HIV transmission risk behavior and seroconversion among Latino men who have sex with men in Project EXPLORE. AIDS Behav. 2012 Apr; 16(3):608-17.
    View in: PubMed
  32. O'Cleirigh C, Safren SA, Mayer KH. The pervasive effects of childhood sexual abuse: challenges for improving HIV prevention and treatment interventions. J Acquir Immune Defic Syndr. 2012 Apr 1; 59(4):331-4.
    View in: PubMed
  33. Skeer MR, Mimiaga MJ, Mayer KH, O'Cleirigh C, Covahey C, Safren SA. Patterns of substance use among a large urban cohort of HIV-infected men who have sex with men in primary care. AIDS Behav. 2012 Apr; 16(3):676-89.
    View in: PubMed
  34. Markowitz SM, Carper MM, Gonzalez JS, Delahanty LM, Safren SA. Cognitive-behavioral therapy for the treatment of depression and adherence in patients with type 1 diabetes: pilot data and feasibility. Prim Care Companion CNS Disord. 2012; 14(2).
    View in: PubMed
  35. Safren SA, Hendriksen ES, Smeaton L, Celentano DD, Hosseinipour MC, Barnett R, Guanira J, Flanigan T, Kumarasamy N, Klingman K, Campbell T. Quality of life among individuals with HIV starting antiretroviral therapy in diverse resource-limited areas of the world. AIDS Behav. 2012 Feb; 16(2):266-77.
    View in: PubMed
  36. Coleman SM, Blashill AJ, Gandhi RT, Safren SA, Freudenreich O. Impact of integrated and measurement-based depression care: clinical experience in an HIV clinic. Psychosomatics. 2012 Jan-Feb; 53(1):51-7.
    View in: PubMed
  37. Hatzenbuehler ML, O'Cleirigh C, Grasso C, Mayer K, Safren S, Bradford J. Effect of same-sex marriage laws on health care use and expenditures in sexual minority men: a quasi-natural experiment. Am J Public Health. 2012 Feb; 102(2):285-91.
    View in: PubMed
  38. Thomas B, Mimiaga MJ, Kumar S, Swaminathan S, Safren SA, Mayer KH. HIV in Indian MSM: reasons for a concentrated epidemic & strategies for prevention. Indian J Med Res. 2011 Dec; 134(6):920-9.
    View in: PubMed
  39. Blashill AJ, Perry N, Safren SA. Mental health: a focus on stress, coping, and mental illness as it relates to treatment retention, adherence, and other health outcomes. Curr HIV/AIDS Rep. 2011 Dec; 8(4):215-22.
    View in: PubMed
  40. Traeger L, O'Cleirigh C, Skeer MR, Mayer KH, Safren SA. Risk factors for missed HIV primary care visits among men who have sex with men. J Behav Med. 2012 Oct; 35(5):548-56.
    View in: PubMed
  41. Markowitz SM, O'Cleirigh C, Hendriksen ES, Bullis JR, Stein M, Safren SA. Childhood sexual abuse and health risk behaviors in patients with HIV and a history of injection drug use. AIDS Behav. 2011 Oct; 15(7):1554-60.
    View in: PubMed
  42. Hatzenbuehler ML, O'Cleirigh C, Mayer KH, Mimiaga MJ, Safren SA. Prospective associations between HIV-related stigma, transmission risk behaviors, and adverse mental health outcomes in men who have sex with men. Ann Behav Med. 2011 Oct; 42(2):227-34.
    View in: PubMed
  43. Gonzalez JS, Batchelder AW, Psaros C, Safren SA. Depression and HIV/AIDS treatment nonadherence: a review and meta-analysis. J Acquir Immune Defic Syndr. 2011 Oct 1; 58(2):181-7.
    View in: PubMed
  44. Gonzalez JS, Psaros C, Batchelder A, Applebaum A, Newville H, Safren SA. Clinician-assessed depression and HAART adherence in HIV-infected individuals in methadone maintenance treatment. Ann Behav Med. 2011 Aug; 42(1):120-6.
    View in: PubMed
  45. Sivasubramanian M, Mimiaga MJ, Mayer KH, Anand VR, Johnson CV, Prabhugate P, Safren SA. Suicidality, clinical depression, and anxiety disorders are highly prevalent in men who have sex with men in Mumbai, India: findings from a community-recruited sample. Psychol Health Med. 2011 Aug; 16(4):450-62.
    View in: PubMed
  46. Walensky RP, Reichmann WM, Arbelaez C, Wright E, Katz JN, Seage GR, Safren SA, Hare AQ, Novais A, Losina E. Counselor- versus provider-based HIV screening in the emergency department: results from the universal screening for HIV infection in the emergency room (USHER) randomized controlled trial. Ann Emerg Med. 2011 Jul; 58(1 Suppl 1):S126-32.e1-4.
    View in: PubMed
  47. Safren SA, O'Cleirigh C, Skeer MR, Driskell J, Goshe BM, Covahey C, Mayer KH. Demonstration and evaluation of a peer-delivered, individually-tailored, HIV prevention intervention for HIV-infected MSM in their primary care setting. AIDS Behav. 2011 Jul; 15(5):949-58.
    View in: PubMed
  48. Venkatesh KK, Srikrishnan AK, Safren SA, Triche EW, Thamburaj E, Prasad L, Lurie MN, Kumar MS, Kumarasamy N, Solomon S, Mayer KH. Sexual risk behaviors among HIV-infected South Indian couples in the HAART era: implications for reproductive health and HIV care delivery. AIDS Care. 2011 Jun; 23(6):722-33.
    View in: PubMed
  49. Moore JO, Boyer EW, Safren S, Robbins GK, Boudreaux ED, Rosen R, Barton B, Moss F. Designing interventions to overcome poor numeracy and improve medication adherence in chronic illness, including HIV/AIDS. J Med Toxicol. 2011 Jun; 7(2):133-8.
    View in: PubMed
  50. Laws MB, Bradshaw YS, Safren SA, Beach MC, Lee Y, Rogers W, Wilson IB. Discussion of sexual risk behavior in HIV care is infrequent and appears ineffectual: a mixed methods study. AIDS Behav. 2011 May; 15(4):812-22.
    View in: PubMed
  51. Betancourt TS, Rubin-Smith JE, Beardslee WR, Stulac SN, Fayida I, Safren S. Understanding locally, culturally, and contextually relevant mental health problems among Rwandan children and adolescents affected by HIV/AIDS. AIDS Care. 2011 Apr; 23(4):401-12.
    View in: PubMed
  52. Safren SA, Blashill AJ, O'Cleirigh CM. Promoting the sexual health of MSM in the context of comorbid mental health problems. AIDS Behav. 2011 Apr; 15 Suppl 1:S30-4.
    View in: PubMed
  53. Mimiaga MJ, Thomas B, Mayer KH, Reisner SL, Menon S, Swaminathan S, Periyasamy M, Johnson CV, Safren SA. Alcohol use and HIV sexual risk among MSM in Chennai, India. Int J STD AIDS. 2011 Mar; 22(3):121-5.
    View in: PubMed
  54. Simoni JM, Safren SA, Manhart LE, Lyda K, Grossman CI, Rao D, Mimiaga MJ, Wong FY, Catz SL, Blank MB, DiClemente R, Wilson IB. Challenges in addressing depression in HIV research: assessment, cultural context, and methods. AIDS Behav. 2011 Feb; 15(2):376-88.
    View in: PubMed
  55. Markowitz SM, Gonzalez JS, Wilkinson JL, Safren SA. A review of treating depression in diabetes: emerging findings. Psychosomatics. 2011 Jan-Feb; 52(1):1-18.
    View in: PubMed
  56. Safren SA, Reisner SL, Herrick A, Mimiaga MJ, Stall RD. Mental health and HIV risk in men who have sex with men. J Acquir Immune Defic Syndr. 2010 Dec; 55 Suppl 2:S74-7.
    View in: PubMed
  57. Venkatesh KK, Srikrishnan AK, Mayer KH, Kumarasamy N, Raminani S, Thamburaj E, Prasad L, Triche EW, Solomon S, Safren SA. Predictors of nonadherence to highly active antiretroviral therapy among HIV-infected South Indians in clinical care: implications for developing adherence interventions in resource-limited settings. AIDS Patient Care STDS. 2010 Dec; 24(12):795-803.
    View in: PubMed
  58. Vranceanu AM, Safren S. Cognitive-behavioral therapy for hand and arm pain. J Hand Ther. 2011 Apr-Jun; 24(2):124-30; quiz 131.
    View in: PubMed
  59. Applebaum AJ, Otto MW, Richardson MA, Safren SA. Contributors to neuropsychological impairment in HIV-infected and HIV-uninfected opiate-dependent patients. J Clin Exp Neuropsychol. 2010 Jul; 32(6):579-89.
    View in: PubMed
  60. Freudenreich O, Goforth HW, Cozza KL, Mimiaga MJ, Safren SA, Bachmann G, Cohen MA. Psychiatric treatment of persons with HIV/AIDS: an HIV-psychiatry consensus survey of current practices. Psychosomatics. 2010 Nov-Dec; 51(6):480-8.
    View in: PubMed
  61. Mimiaga MJ, Safren SA, Dvoryak S, Reisner SL, Needle R, Woody G. "We fear the police, and the police fear us": structural and individual barriers and facilitators to HIV medication adherence among injection drug users in Kiev, Ukraine. AIDS Care. 2010 Nov; 22(11):1305-13.
    View in: PubMed
  62. Meade CS, Conn NA, Skalski LM, Safren SA. Neurocognitive impairment and medication adherence in HIV patients with and without cocaine dependence. J Behav Med. 2011 Apr; 34(2):128-38.
    View in: PubMed
  63. Knouse LE, Safren SA. Current status of cognitive behavioral therapy for adult attention-deficit hyperactivity disorder. Psychiatr Clin North Am. 2010 Sep; 33(3):497-509.
    View in: PubMed
  64. Safren SA, Sprich S, Mimiaga MJ, Surman C, Knouse L, Groves M, Otto MW. Cognitive behavioral therapy vs relaxation with educational support for medication-treated adults with ADHD and persistent symptoms: a randomized controlled trial. JAMA. 2010 Aug 25; 304(8):875-80.
    View in: PubMed
  65. Vranceanu AM, Safren SA, Cowan J, Ring DC. Health concerns and somatic symptoms explain perceived disability and idiopathic hand and arm pain in an orthopedics surgical practice: a path-analysis model. Psychosomatics. 2010 Jul-Aug; 51(4):330-7.
    View in: PubMed
  66. Bottonari KA, Safren SA, McQuaid JR, Hsiao CB, Roberts JE. A longitudinal investigation of the impact of life stress on HIV treatment adherence. J Behav Med. 2010 Dec; 33(6):486-95.
    View in: PubMed
  67. Reisner SL, Mimiaga MJ, Johnson CV, Bland S, Case P, Safren SA, Mayer KH. What makes a respondent-driven sampling "seed" productive? Example of finding at-risk Massachusetts men who have sex with men. J Urban Health. 2010 May; 87(3):467-79.
    View in: PubMed
  68. Velligan D, Sajatovic M, Valenstein M, Riley WT, Safren S, Lewis-Fernandez R, Weiden P, Ogedegbe G, Jamison J. Methodological challenges in psychiatric treatment adherence research. Clin Schizophr Relat Psychoses. 2010 Apr; 4(1):74-91.
    View in: PubMed
  69. Mayer KH, Mimiaga MJ, Safren SA. Out of the Closet and Into Public Health Focus: HIV and STDs in Men Who Have Sex With Men in Middle Income and Resource-Limited Countries. Sex Transm Dis. 2010 Apr; 37(4):205-7.
    View in: PubMed
  70. Safren SA, Traeger L, Skeer MR, O'Cleirigh C, Meade CS, Covahey C, Mayer KH. Testing a social-cognitive model of HIV transmission risk behaviors in HIV-infected MSM with and without depression. Health Psychol. 2010 Mar; 29(2):215-21.
    View in: PubMed
  71. Wilson IB, Laws MB, Safren SA, Lee Y, Lu M, Coady W, Skolnik PR, Rogers WH. Provider-focused intervention increases adherence-related dialogue but does not improve antiretroviral therapy adherence in persons with HIV. J Acquir Immune Defic Syndr. 2010 Mar; 53(3):338-47.
    View in: PubMed
  72. Reichmann WM, Losina E, Seage GR, Arbelaez C, Safren SA, Katz JN, Hetland A, Walensky RP. Does modality of survey administration impact data quality: audio computer assisted self interview (ACASI) versus self-administered pen and paper? PLoS One. 2010; 5(1):e8728.
    View in: PubMed
  73. Mimiaga MJ, Reichmann WM, Safren SA, Losina E, Arbelaez C, Walensky RP. Prevalence and correlates of clinically significant depressive symptoms in an urban hospital emergency department. Prim Care Companion J Clin Psychiatry. 2010; 12(2).
    View in: PubMed
  74. Safren SA, Thomas BE, Mimiaga MJ, Chandrasekaran V, Menon S, Swaminathan S, Mayer KH. Depressive symptoms and human immunodeficiency virus risk behavior among men who have sex with men in Chennai, India. Psychol Health Med. 2009 Dec; 14(6):705-15.
    View in: PubMed
  75. Reisner SL, Mimiaga MJ, Safren SA, Mayer KH. Stressful or traumatic life events, post-traumatic stress disorder (PTSD) symptoms, and HIV sexual risk taking among men who have sex with men. AIDS Care. 2009 Dec; 21(12):1481-9.
    View in: PubMed
  76. Thomas B, Mimiaga MJ, Mayer KH, Johnson CV, Menon S, Chandrasekaran V, Murugesan P, Swaminathan S, Safren SA. HIV prevention interventions in Chennai, India: are men who have sex with men being reached? AIDS Patient Care STDS. 2009 Nov; 23(11):981-6.
    View in: PubMed
  77. Reisner SL, Mimiaga MJ, Bland S, Mayer KH, Perkovich B, Safren SA. HIV risk and social networks among male-to-female transgender sex workers in Boston, Massachusetts. J Assoc Nurses AIDS Care. 2009 Sep-Oct; 20(5):373-86.
    View in: PubMed
  78. Mayer KH, O'Cleirigh C, Skeer M, Covahey C, Leidolf E, Vanderwarker R, Safren SA. Which HIV-infected men who have sex with men in care are engaging in risky sex and acquiring sexually transmitted infections: findings from a Boston community health centre. Sex Transm Infect. 2010 Feb; 86(1):66-70.
    View in: PubMed
  79. Thomas B, Mimiaga MJ, Menon S, Chandrasekaran V, Murugesan P, Swaminathan S, Mayer KH, Safren SA. Unseen and unheard: predictors of sexual risk behavior and HIV infection among men who have sex with men in Chennai, India. AIDS Educ Prev. 2009 Aug; 21(4):372-83.
    View in: PubMed
  80. Mimiaga MJ, Noonan E, Donnell D, Safren SA, Koenen KC, Gortmaker S, O'Cleirigh C, Chesney MA, Coates TJ, Koblin BA, Mayer KH. Childhood sexual abuse is highly associated with HIV risk-taking behavior and infection among MSM in the EXPLORE Study. J Acquir Immune Defic Syndr. 2009 Jul 1; 51(3):340-8.
    View in: PubMed
  81. O'Cleirigh C, Skeer M, Mayer KH, Safren SA. Functional impairment and health care utilization among HIV-infected men who have sex with men: the relationship with depression and post-traumatic stress. J Behav Med. 2009 Oct; 32(5):466-77.
    View in: PubMed
  82. Applebaum AJ, Reilly LC, Gonzalez JS, Richardson MA, Leveroni CL, Safren SA. The impact of neuropsychological functioning on adherence to HAART in HIV-infected substance abuse patients. AIDS Patient Care STDS. 2009 Jun; 23(6):455-62.
    View in: PubMed
  83. Safren SA, Sprich SE, Cooper-Vince C, Knouse LE, Lerner JA. Life impairments in adults with medication-treated ADHD. J Atten Disord. 2010 Mar; 13(5):524-31.
    View in: PubMed
  84. Reisner SL, Mimiaga MJ, Skeer M, Perkovich B, Johnson CV, Safren SA. A review of HIV antiretroviral adherence and intervention studies among HIV-infected youth. Top HIV Med. 2009 Feb-Mar; 17(1):14-25.
    View in: PubMed
  85. Safren SA, O'Cleirigh C, Tan JY, Raminani SR, Reilly LC, Otto MW, Mayer KH. A randomized controlled trial of cognitive behavioral therapy for adherence and depression (CBT-AD) in HIV-infected individuals. Health Psychol. 2009 Jan; 28(1):1-10.
    View in: PubMed
  86. Mimiaga MJ, Case P, Johnson CV, Safren SA, Mayer KH. Preexposure antiretroviral prophylaxis attitudes in high-risk Boston area men who report having sex with men: limited knowledge and experience but potential for increased utilization after education. J Acquir Immune Defic Syndr. 2009 Jan 1; 50(1):77-83.
    View in: PubMed
  87. Reisner SL, Mimiaga MJ, Case P, Johnson CV, Safren SA, Mayer KH. Predictors of identifying as a barebacker among high-risk New England HIV seronegative men who have sex with men. J Urban Health. 2009 Mar; 86(2):250-62.
    View in: PubMed
  88. Gonzalez JS, Peyrot M, McCarl LA, Collins EM, Serpa L, Mimiaga MJ, Safren SA. Depression and diabetes treatment nonadherence: a meta-analysis. Diabetes Care. 2008 Dec; 31(12):2398-403.
    View in: PubMed
  89. Knouse LE, Cooper-Vince C, Sprich S, Safren SA. Recent developments in the psychosocial treatment of adult ADHD. Expert Rev Neurother. 2008 Oct; 8(10):1537-48.
    View in: PubMed
  90. Mimiaga MJ, Reisner SL, Tinsley JP, Mayer KH, Safren SA. Street workers and internet escorts: contextual and psychosocial factors surrounding HIV risk behavior among men who engage in sex work with other men. J Urban Health. 2009 Jan; 86(1):54-66.
    View in: PubMed
  91. Mimiaga MJ, Reisner SL, Vanderwarker R, Gaucher MJ, O'Connor CA, Medeiros MS, Safren SA. Polysubstance use and HIV/STD risk behavior among Massachusetts men who have sex with men accessing Department of Public Health mobile van services: implications for intervention development. AIDS Patient Care STDS. 2008 Sep; 22(9):745-51.
    View in: PubMed
  92. Gonzalez JS, Safren SA, Delahanty LM, Cagliero E, Wexler DJ, Meigs JB, Grant RW. Symptoms of depression prospectively predict poorer self-care in patients with Type 2 diabetes. Diabet Med. 2008 Sep; 25(9):1102-7.
    View in: PubMed
  93. Salomon EA, Mimiaga MJ, Husnik MJ, Welles SL, Manseau MW, Montenegro AB, Safren SA, Koblin BA, Chesney MA, Mayer KH. Depressive symptoms, utilization of mental health care, substance use and sexual risk among young men who have sex with men in EXPLORE: implications for age-specific interventions. AIDS Behav. 2009 Aug; 13(4):811-21.
    View in: PubMed
  94. Gonzalez JS, Delahanty LM, Safren SA, Meigs JB, Grant RW. Differentiating symptoms of depression from diabetes-specific distress: relationships with self-care in type 2 diabetes. Diabetologia. 2008 Oct; 51(10):1822-5.
    View in: PubMed
  95. Reisner SL, Mimiaga MJ, Skeer M, Vanderwarker R, Gaucher MJ, O'Connor CA, Susana Medeiros M, Safren SA. Differential HIV risk behavior among men who have sex with men seeking health-related mobile van services at diverse gay-specific venues. AIDS Behav. 2009 Aug; 13(4):822-31.
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  96. Vranceanu AM, Safren S, Zhao M, Cowan J, Ring D. Disability and psychologic distress in patients with nonspecific and specific arm pain. Clin Orthop Relat Res. 2008 Nov; 466(11):2820-6.
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  97. Vranceanu AM, Safren S, Cowan J, Ring D. The development of the negative pain thoughts questionnaire. Pain Pract. 2008 Sep-Oct; 8(5):337-41.
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  98. Gonzalez JS, Hendriksen ES, Collins EM, Durán RE, Safren SA. Latinos and HIV/AIDS: examining factors related to disparity and identifying opportunities for psychosocial intervention research. AIDS Behav. 2009 Jun; 13(3):582-602.
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  99. Weiss M, Safren SA, Solanto MV, Hechtman L, Rostain AL, Ramsay JR, Murray C. Research forum on psychological treatment of adults with ADHD. J Atten Disord. 2008 May; 11(6):642-51.
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  100. O'Cleirigh C, Safren S. Optimizing the effects of stress management interventions in HIV. Health Psychol. 2008 May; 27(3):297-301.
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  101. Berg C, Raminani S, Greer J, Harwood M, Safren S. Participants' perspectives on cognitive-behavioral therapy for adherence and depression in HIV. Psychother Res. 2008 May; 18(3):271-80.
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  102. Vranceanu AM, Safren SA, Lu M, Coady WM, Skolnik PR, Rogers WH, Wilson IB. The relationship of post-traumatic stress disorder and depression to antiretroviral medication adherence in persons with HIV. AIDS Patient Care STDS. 2008 Apr; 22(4):313-21.
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  103. Mimiaga MJ, Skeer M, Mayer KH, Safren SA. Study participation as a social group influencing sexual behaviours in an HIV-prevention trial for men who have sex with men. AIDS Care. 2008 Mar; 20(3):346-55.
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  104. Walkup J, Blank MB, Gonzalez JS, Safren S, Schwartz R, Brown L, Wilson I, Knowlton A, Lombard F, Grossman C, Lyda K, Schumacher JE. The impact of mental health and substance abuse factors on HIV prevention and treatment. J Acquir Immune Defic Syndr. 2008 Mar 1; 47 Suppl 1:S15-9.
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  105. Mimiaga MJ, Fair AD, Mayer KH, Koenen K, Gortmaker S, Tetu AM, Hobson J, Safren SA. Experiences and sexual behaviors of HIV-infected MSM who acquired HIV in the context of crystal methamphetamine use. AIDS Educ Prev. 2008 Feb; 20(1):30-41.
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  106. Harley R, Sprich S, Safren S, Jacobo M, Fava M. Adaptation of dialectical behavior therapy skills training group for treatment-resistant depression. J Nerv Ment Dis. 2008 Feb; 196(2):136-43.
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  107. Reisner SL, Mimiaga MJ, Mayer KH, Tinsley JP, Safren SA. Tricks of the trade: sexual health behaviors, the context of HIV risk, and potential prevention intervention strategies for male sex workers. J LGBT Health Res. 2008; 4(4):195-209.
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  108. Berg MB, Mimiaga MJ, Safren SA. Mental health concerns of gay and bisexual men seeking mental health services. J Homosex. 2008; 54(3):293-306.
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  109. Safren SA, Wingood G, Altice FL. Strategies for primary HIV prevention that target behavioral change. Clin Infect Dis. 2007 Dec 15; 45 Suppl 4:S300-307.
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  110. Sri Krishnan AK, Hendriksen E, Vallabhaneni S, Johnson SL, Raminani S, Kumarasamy N, Hobsen J, Solomon S, Mayer KH, Safren SA. Sexual behaviors of individuals with HIV living in South India: a qualitative study. AIDS Educ Prev. 2007 Aug; 19(4):334-45.
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  111. Knauz RO, Safren SA, O'Cleirigh C, Capistrant BD, Driskell JR, Aguilar D, Salomon L, Hobson J, Mayer KH. Developing an HIV-prevention intervention for HIV-infected men who have sex with men in HIV care: project enhance. AIDS Behav. 2007 Sep; 11(5 Suppl):S117-26.
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  112. Lu M, Safren SA, Skolnik PR, Rogers WH, Coady W, Hardy H, Wilson IB. Optimal recall period and response task for self-reported HIV medication adherence. AIDS Behav. 2008 Jan; 12(1):86-94.
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  113. Gonzalez JS, Safren SA, Cagliero E, Wexler DJ, Delahanty L, Wittenberg E, Blais MA, Meigs JB, Grant RW. Depression, self-care, and medication adherence in type 2 diabetes: relationships across the full range of symptom severity. Diabetes Care. 2007 Sep; 30(9):2222-7.
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  114. Berg CJ, Michelson SE, Safren SA. Behavioral aspects of HIV care: adherence, depression, substance use, and HIV-transmission behaviors. Infect Dis Clin North Am. 2007 Mar; 21(1):181-200, x.
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  115. Safren SA, Duran P, Yovel I, Perlman CA, Sprich S. Medication adherence in psychopharmacologically treated adults with ADHD. J Atten Disord. 2007 Feb; 10(3):257-60.
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  116. Olatunji BO, Mimiaga MJ, O'Cleirigh C, Safren SA. Review of treatment studies of depression in HIV. Top HIV Med. 2006 Aug-Sep; 14(3):112-24.
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  117. Safren SA, Martin C, Menon S, Greer J, Solomon S, Mimiaga MJ, Mayer KH. A survey of MSM HIV prevention outreach workers in Chennai, India. AIDS Educ Prev. 2006 Aug; 18(4):323-32.
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  118. Safren SA, Kumarasamy N, Hosseinipour M, Harwood MM, Hoffman I, McCauley M, Jumbe A, Nyirenda C, Mimiaga MJ, Solomon S, Celentano D, Mayer KH. Perceptions about the acceptability of assessments of HIV medication adherence in Lilongwe, Malawi and Chennai, India. AIDS Behav. 2006 Jul; 10(4):443-50.
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  119. Hinton DE, Pich V, Chhean D, Safren SA, Pollack MH. Somatic-focused therapy for traumatized refugees: Treating posttraumatic stress disorder and comorbid neck-focused panic attacks among cambodian refugees. Psychotherapy (Chic). 2006; 43(4):491-505.
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  120. O'Cleirigh C, Safren SA. Domains of life satisfaction among patients living with HIV: A factor analytic study of the quality of life inventory. AIDS Behav. 2006 Jan; 10(1):53-8.
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  121. Biederman J, Arnsten AF, Faraone SV, Doyle AE, Spencer TJ, Wilens TE, Weiss MD, Safren SA, Culpepper L. New developments in the treatment of ADHD. J Clin Psychiatry. 2006 Jan; 67(1):148-59.
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  122. Hinton DE, Pich V, Safren SA, Pollack MH, McNally RJ. Anxiety sensitivity among Cambodian refugees with panic disorder: A factor analytic investigation. J Anxiety Disord. 2006; 20(3):281-95.
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  123. Safren SA. Cognitive-behavioral approaches to ADHD treatment in adulthood. J Clin Psychiatry. 2006; 67 Suppl 8:46-50.
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  124. Mimiaga MJ, Safren SA, Benet DJ, Manseau MW, DeSousa N, Mayer KH. MSM in HIV-prevention trials are sexual partners with each other: An ancillary study to the EXPLORE intervention. AIDS Behav. 2006 Jan; 10(1):27-34.
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  125. Pirl WF, Greer JA, Weissgarber C, Liverant G, Safren SA. Screening for infectious diseases among patients in a state psychiatric hospital. Psychiatr Serv. 2005 Dec; 56(12):1614-6.
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  126. Hinton DE, Chhean D, Pich V, Safren SA, Hofmann SG, Pollack MH. A randomized controlled trial of cognitive-behavior therapy for Cambodian refugees with treatment-resistant PTSD and panic attacks: a cross-over design. J Trauma Stress. 2005 Dec; 18(6):617-29.
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  127. Hinton DE, Pich V, Safren SA, Pollack MH, McNally RJ. Anxiety sensitivity in traumatized Cambodian refugees: a discriminant function and factor analytic investigation. Behav Res Ther. 2005 Dec; 43(12):1631-43.
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  128. Safren SA, Kumarasamy N, James R, Raminani S, Solomon S, Mayer KH. ART adherence, demographic variables and CD4 outcome among HIV-positive patients on antiretroviral therapy in Chennai, India. AIDS Care. 2005 Oct; 17(7):853-62.
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  129. Berg MB, Safren SA, Mimiaga MJ, Grasso C, Boswell S, Mayer KH. Nonadherence to medical appointments is associated with increased plasma HIV RNA and decreased CD4 cell counts in a community-based HIV primary care clinic. AIDS Care. 2005 Oct; 17(7):902-7.
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  130. Kumarasamy N, Safren SA, Raminani SR, Pickard R, James R, Krishnan AK, Solomon S, Mayer KH. Barriers and facilitators to antiretroviral medication adherence among patients with HIV in Chennai, India: a qualitative study. AIDS Patient Care STDS. 2005 Aug; 19(8):526-37.
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  131. Safren SA, Otto MW, Sprich S, Winett CL, Wilens TE, Biederman J. Cognitive-behavioral therapy for ADHD in medication-treated adults with continued symptoms. Behav Res Ther. 2005 Jul; 43(7):831-42.
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  132. Eng W, Coles ME, Heimberg RG, Safren SA. Domains of life satisfaction in social anxiety disorder: relation to symptoms and response to cognitive-behavioral therapy. J Anxiety Disord. 2005; 19(2):143-56.
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  133. Berg MB, Mimiaga MJ, Safren SA. Mental health concerns of HIV-infected gay and bisexual men seeking mental health services: an observational study. AIDS Patient Care STDS. 2004 Nov; 18(11):635-43.
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  134. Mayer KH, Safren SA, Gordon CM. HIV care providers and prevention: opportunities and challenges. J Acquir Immune Defic Syndr. 2004 Oct 1; 37 Suppl 2:S130-2.
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  135. Hinton DE, Pham T, Tran M, Safren SA, Otto MW, Pollack MH. CBT for Vietnamese refugees with treatment-resistant PTSD and panic attacks: a pilot study. J Trauma Stress. 2004 Oct; 17(5):429-33.
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  136. Safren SA, Sprich S, Chulvick S, Otto MW. Psychosocial treatments for adults with attention-deficit/hyperactivity disorder. Psychiatr Clin North Am. 2004 Jun; 27(2):349-60.
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  137. Otto MW, Safren SA, Pollack MH. Internal cue exposure and the treatment of substance use disorders: lessons from the treatment of panic disorder. J Anxiety Disord. 2004; 18(1):69-87.
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  138. Safren SA, Hendriksen ES, Desousa N, Boswell SL, Mayer KH. Use of an on-line pager system to increase adherence to antiretroviral medications. AIDS Care. 2003 Dec; 15(6):787-93.
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  139. Safren SA, Gershuny BS, Hendriksen E. Symptoms of posttraumatic stress and death anxiety in persons with HIV and medication adherence difficulties. AIDS Patient Care STDS. 2003 Dec; 17(12):657-64.
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  140. Safren SA, Radomsky AS, Otto MW, Salomon E. Predictors of psychological well-being in a diverse sample of HIV-positive patients receiving highly active antiretroviral therapy. Psychosomatics. 2002 Nov-Dec; 43(6):478-85.
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  141. Safren SA, Gershuny BS, Marzol P, Otto MW, Pollack MH. History of childhood abuse in panic disorder, social phobia, and generalized anxiety disorder. J Nerv Ment Dis. 2002 Jul; 190(7):453-6.
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  142. Simon NM, Safren SA, Otto MW, Sharma SG, Lanka GD, Pollack MH. Longitudinal outcome with pharmacotherapy in a naturalistic study of panic disorder. J Affect Disord. 2002 May; 69(1-3):201-8.
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  143. Otto MW, Hong JJ, Safren SA. Benzodiazepine discontinuation difficulties in panic disorder: conceptual model and outcome for cognitive-behavior therapy. Curr Pharm Des. 2002; 8(1):75-80.
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  144. Pirl WF, Beck BJ, Safren SA, Kim H. A Descriptive Study of Psychiatric Consultations in a Community Primary Care Center. Prim Care Companion J Clin Psychiatry. 2001 Oct; 3(5):190-194.
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  145. Safren SA, Otto MW, Worth JL, Salomon E, Johnson W, Mayer K, Boswell S. Two strategies to increase adherence to HIV antiretroviral medication: life-steps and medication monitoring. Behav Res Ther. 2001 Oct; 39(10):1151-62.
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  146. Safren SA, Rogers T. Cognitive-behavioral therapy with gay, lesbian, and bisexual clients. J Clin Psychol. 2001 May; 57(5):629-43.
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  147. Eng W, Coles ME, Heimberg RG, Safren SA. Quality of life following cognitive behavioral treatment for social anxiety disorder: preliminary findings. Depress Anxiety. 2001; 13(4):192-3.
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  148. Safren SA, Lanka GD, Otto MW, Pollack MH. Prevalence of childhood ADHD among patients with Generalized Anxiety Disorder and a comparison condition, Social Phobia. Depress Anxiety. 2001; 13(4):190-1.
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  149. Safren SA, Gonzalez RE, Horner KJ, Leung AW, Heimberg RG, Juster HR. Anxiety in ethnic minority youth. Methodological and conceptual issues and review of the literature. Behav Modif. 2000 Apr; 24(2):147-83.
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  150. Safren SA, Heimberg RG. Depression, hopelessness, suicidality, and related factors in sexual minority and heterosexual adolescents. J Consult Clin Psychol. 1999 Dec; 67(6):859-66.
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  151. Safren SA, Heimberg RG, Horner KJ, Juster HR, Schneier FR, Liebowitz MR. Factor structure of social fears: The Liebowitz Social Anxiety Scale. J Anxiety Disord. 1999 May-Jun; 13(3):253-70.
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  152. Lerner J, Safren SA, Henin A, Warman M, Heimberg RG, Kendall PC. Differentiating anxious and depressive self-statements in youth: factor structure of the Negative Affect Self-Statement Questionnaire among youth referred to an anxiety disorders clinic. J Clin Child Psychol. 1999 Mar; 28(1):82-93.
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  153. Heimberg RG, Horner KJ, Juster HR, Safren SA, Brown EJ, Schneier FR, Liebowitz MR. Psychometric properties of the Liebowitz Social Anxiety Scale. Psychol Med. 1999 Jan; 29(1):199-212.
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  154. Safren SA, Turk CL, Heimberg RG. Factor structure of the Social Interaction Anxiety Scale and the Social Phobia Scale. Behav Res Ther. 1998 Apr; 36(4):443-53.
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  155. Safren SA, Heimberg RG, Juster HR. Clients' expectancies and their relationship to pretreatment symptomatology and outcome of cognitive-behavioral group treatment for social phobia. J Consult Clin Psychol. 1997 Aug; 65(4):694-8.
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  156. Safren SA, Heimberg RG, Brown EJ, Holle C. Quality of life in social phobia. Depress Anxiety. 1996-1997; 4(3):126-33.
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