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Elfar Adalsteinsson, PH.D.

TitleMember of the Faculty of Health Sciences and Technology
InstitutionMassachusetts Institute of Technology
DepartmentHealth Sciences and Technology
AddressMass Institute Of Technology
E E C S, 26-355
77 Massachusetts Ave
Cambridge MA 02139
Phone617/324-3597

 Bibliographic 
 selected publications
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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  1. Bilgic B, Setsompop K, Cohen-Adad J, Yendiki A, Wald LL, Adalsteinsson E. Accelerated diffusion spectrum imaging with compressed sensing using adaptive dictionaries. Magn Reson Med. 2012 Dec; 68(6):spcone.
    View in: PubMed
  2. Bilgic B, Setsompop K, Cohen-Adad J, Yendiki A, Wald LL, Adalsteinsson E. Accelerated diffusion spectrum imaging with compressed sensing using adaptive dictionaries. Magn Reson Med. 2012 Dec; 68(6):1747-54.
    View in: PubMed
  3. Bilgic B, Setsompop K, Cohen-Adad J, Wedeen V, Wald LL, Adalsteinsson E. Accelerated diffusion spectrum imaging with compressed sensing using adaptive dictionaries. Med Image Comput Comput Assist Interv. 2012; 15(Pt 3):1-9.
    View in: PubMed
  4. Weller DS, Polimeni JR, Grady L, Wald LL, Adalsteinsson E, Goyal VK. Denoising sparse images from GRAPPA using the nullspace method. Magn Reson Med. 2012 Oct; 68(4):1176-89.
    View in: PubMed
  5. Lee J, Gebhardt M, Wald LL, Adalsteinsson E. Local SAR in parallel transmission pulse design. Magn Reson Med. 2012 Jun; 67(6):1566-78.
    View in: PubMed
  6. Bilgic B, Pfefferbaum A, Rohlfing T, Sullivan EV, Adalsteinsson E. MRI estimates of brain iron concentration in normal aging using quantitative susceptibility mapping. Neuroimage. 2012 Feb 1; 59(3):2625-35.
    View in: PubMed
  7. Andronesi OC, Gagoski BA, Adalsteinsson E, Sorensen AG. Correlation chemical shift imaging with low-power adiabatic pulses and constant-density spiral trajectories. NMR Biomed. 2012 Feb; 25(2):195-209.
    View in: PubMed
  8. Fan AP, Benner T, Bolar DS, Rosen BR, Adalsteinsson E. Phase-based regional oxygen metabolism (PROM) using MRI. Magn Reson Med. 2012 Mar; 67(3):669-78.
    View in: PubMed
  9. Bolar DS, Rosen BR, Sorensen AG, Adalsteinsson E. QUantitative Imaging of eXtraction of oxygen and TIssue consumption (QUIXOTIC) using venular-targeted velocity-selective spin labeling. Magn Reson Med. 2011 Dec; 66(6):1550-62.
    View in: PubMed
  10. Bilgic B, Goyal VK, Adalsteinsson E. Multi-contrast reconstruction with Bayesian compressed sensing. Magn Reson Med. 2011 Dec; 66(6):1601-15.
    View in: PubMed
  11. Cantillon-Murphy P, Wald LL, Zahn M, Adalsteinsson E. Measuring SPIO and Gd contrast agent magnetization using 3 T MRI. NMR Biomed. 2009 Oct; 22(8):891-7.
    View in: PubMed
  12. Pfefferbaum A, Adalsteinsson E, Rohlfing T, Sullivan EV. MRI estimates of brain iron concentration in normal aging: comparison of field-dependent (FDRI) and phase (SWI) methods. Neuroimage. 2009 Aug 15; 47(2):493-500.
    View in: PubMed
  13. Setsompop K, Alagappan V, Gagoski BA, Potthast A, Hebrank F, Fontius U, Schmitt F, Wald LL, Adalsteinsson E. Broadband slab selection with B1+ mitigation at 7T via parallel spectral-spatial excitation. Magn Reson Med. 2009 Feb; 61(2):493-500.
    View in: PubMed
  14. Setsompop K, Alagappan V, Gagoski B, Witzel T, Polimeni J, Potthast A, Hebrank F, Fontius U, Schmitt F, Wald LL, Adalsteinsson E. Slice-selective RF pulses for in vivo B1+ inhomogeneity mitigation at 7 tesla using parallel RF excitation with a 16-element coil. Magn Reson Med. 2008 Dec; 60(6):1422-32.
    View in: PubMed
  15. Ratai E, Kok T, Wiggins C, Wiggins G, Grant E, Gagoski B, O'Neill G, Adalsteinsson E, Eichler F. Seven-Tesla proton magnetic resonance spectroscopic imaging in adult X-linked adrenoleukodystrophy. Arch Neurol. 2008 Nov; 65(11):1488-94.
    View in: PubMed
  16. Zelinski AC, Angelone LM, Goyal VK, Bonmassar G, Adalsteinsson E, Wald LL. Specific absorption rate studies of the parallel transmission of inner-volume excitations at 7T. J Magn Reson Imaging. 2008 Oct; 28(4):1005-18.
    View in: PubMed
  17. Zelinski AC, Wald LL, Setsompop K, Goyal VK, Adalsteinsson E. Sparsity-enforced slice-selective MRI RF excitation pulse design. IEEE Trans Med Imaging. 2008 Sep; 27(9):1213-29.
    View in: PubMed
  18. Setsompop K, Alagappan V, Zelinski AC, Potthast A, Fontius U, Hebrank F, Schmitt F, Wald LL, Adalsteinsson E. High-flip-angle slice-selective parallel RF transmission with 8 channels at 7 T. J Magn Reson. 2008 Nov; 195(1):76-84.
    View in: PubMed
  19. Zelinski AC, Wald LL, Setsompop K, Alagappan V, Gagoski BA, Goyal VK, Adalsteinsson E. Fast slice-selective radio-frequency excitation pulses for mitigating B+1 inhomogeneity in the human brain at 7 Tesla. Magn Reson Med. 2008 Jun; 59(6):1355-64.
    View in: PubMed
  20. Pfefferbaum A, Adalsteinsson E, Rohlfing T, Sullivan EV. Diffusion tensor imaging of deep gray matter brain structures: effects of age and iron concentration. Neurobiol Aging. 2010 Mar; 31(3):482-93.
    View in: PubMed
  21. Setsompop K, Wald LL, Alagappan V, Gagoski BA, Adalsteinsson E. Magnitude least squares optimization for parallel radio frequency excitation design demonstrated at 7 Tesla with eight channels. Magn Reson Med. 2008 Apr; 59(4):908-15.
    View in: PubMed
  22. Alagappan V, Nistler J, Adalsteinsson E, Setsompop K, Fontius U, Zelinski A, Vester M, Wiggins GC, Hebrank F, Renz W, Schmitt F, Wald LL. Degenerate mode band-pass birdcage coil for accelerated parallel excitation. Magn Reson Med. 2007 Jun; 57(6):1148-58.
    View in: PubMed
  23. Mayer D, Zahr NM, Adalsteinsson E, Rutt B, Sullivan EV, Pfefferbaum A. In vivo fiber tracking in the rat brain on a clinical 3T MRI system using a high strength insert gradient coil. Neuroimage. 2007 Apr 15; 35(3):1077-85.
    View in: PubMed
  24. Setsompop K, Wald LL, Alagappan V, Gagoski B, Hebrank F, Fontius U, Schmitt F, Adalsteinsson E. Parallel RF transmission with eight channels at 3 Tesla. Magn Reson Med. 2006 Nov; 56(5):1163-71.
    View in: PubMed
  25. Pfefferbaum A, Rosenbloom MJ, Adalsteinsson E, Sullivan EV. Diffusion tensor imaging with quantitative fibre tracking in HIV infection and alcoholism comorbidity: synergistic white matter damage. Brain. 2007 Jan; 130(Pt 1):48-64.
    View in: PubMed
  26. Pfefferbaum A, Rosenbloom MJ, Rohlfing T, Adalsteinsson E, Kemper CA, Deresinski S, Sullivan EV. Contribution of alcoholism to brain dysmorphology in HIV infection: effects on the ventricles and corpus callosum. Neuroimage. 2006 Oct 15; 33(1):239-51.
    View in: PubMed
  27. Sullivan EV, Adalsteinsson E, Sood R, Mayer D, Bell R, McBride W, Li TK, Pfefferbaum A. Longitudinal brain magnetic resonance imaging study of the alcohol-preferring rat. Part I: adult brain growth. Alcohol Clin Exp Res. 2006 Jul; 30(7):1234-47.
    View in: PubMed
  28. Pfefferbaum A, Adalsteinsson E, Sood R, Mayer D, Bell R, McBride W, Li TK, Sullivan EV. Longitudinal brain magnetic resonance imaging study of the alcohol-preferring rat. Part II: effects of voluntary chronic alcohol consumption. Alcohol Clin Exp Res. 2006 Jul; 30(7):1248-61.
    View in: PubMed
  29. Pfefferbaum A, Adalsteinsson E, Bell RL, Sullivan EV. Development and resolution of brain lesions caused by pyrithiamine- and dietary-induced thiamine deficiency and alcohol exposure in the alcohol-preferring rat: a longitudinal magnetic resonance imaging and spectroscopy study. Neuropsychopharmacology. 2007 May; 32(5):1159-77.
    View in: PubMed
  30. Mayer D, Kim DH, Adalsteinsson E, Spielman DM. Fast CT-PRESS-based spiral chemical shift imaging at 3 Tesla. Magn Reson Med. 2006 May; 55(5):974-8.
    View in: PubMed
  31. Adalsteinsson E, Sullivan EV, Mayer D, Pfefferbaum A. In vivo quantification of ethanol kinetics in rat brain. Neuropsychopharmacology. 2006 Dec; 31(12):2683-91.
    View in: PubMed
  32. Schulte T, Chen SH, Müller-Oehring EM, Adalsteinsson E, Pfefferbaum A, Sullivan EV. fMRI evidence for individual differences in premotor modulation of extrastriatal visual-perceptual processing of redundant targets. Neuroimage. 2006 Apr 15; 30(3):973-82.
    View in: PubMed
  33. Sullivan EV, Adalsteinsson E, Pfefferbaum A. Selective age-related degradation of anterior callosal fiber bundles quantified in vivo with fiber tracking. Cereb Cortex. 2006 Jul; 16(7):1030-9.
    View in: PubMed
  34. Pfefferbaum A, Adalsteinsson E, Sullivan EV. Supratentorial profile of white matter microstructural integrity in recovering alcoholic men and women. Biol Psychiatry. 2006 Feb 15; 59(4):364-72.
    View in: PubMed
  35. Crowley K, Sullivan EV, Adalsteinsson E, Pfefferbaum A, Colrain IM. Differentiating pathologic delta from healthy physiologic delta in patients with Alzheimer disease. Sleep. 2005 Jul; 28(7):865-70.
    View in: PubMed
  36. Pfefferbaum A, Adalsteinsson E, Sullivan EV. Cortical NAA deficits in HIV infection without dementia: influence of alcoholism comorbidity. Neuropsychopharmacology. 2005 Jul; 30(7):1392-9.
    View in: PubMed
  37. Pfefferbaum A, Adalsteinsson E, Sullivan EV. Dysmorphology and microstructural degradation of the corpus callosum: Interaction of age and alcoholism. Neurobiol Aging. 2006 Jul; 27(7):994-1009.
    View in: PubMed
  38. Pfefferbaum A, Adalsteinsson E, Sullivan EV. Frontal circuitry degradation marks healthy adult aging: Evidence from diffusion tensor imaging. Neuroimage. 2005 Jul 1; 26(3):891-9.
    View in: PubMed
  39. Sullivan EV, Sable HJ, Strother WN, Friedman DP, Davenport A, Tillman-Smith H, Kraft RA, Wyatt C, Szeliga KT, Buchheimer NC, Daunais JB, Adalsteinsson E, Pfefferbaum A, Grant KA. Neuroimaging of rodent and primate models of alcoholism: initial reports from the integrative neuroscience initiative on alcoholism. Alcohol Clin Exp Res. 2005 Feb; 29(2):287-94.
    View in: PubMed
  40. Schulte T, Sullivan EV, Müller-Oehring EM, Adalsteinsson E, Pfefferbaum A. Corpus callosal microstructural integrity influences interhemispheric processing: a diffusion tensor imaging study. Cereb Cortex. 2005 Sep; 15(9):1384-92.
    View in: PubMed
  41. Pfefferbaum A, Adalsteinsson E, Sullivan EV. In vivo structural imaging of the rat brain with a 3-T clinical human scanner. J Magn Reson Imaging. 2004 Nov; 20(5):779-85.
    View in: PubMed
  42. Adalsteinsson E, Hurd RE, Mayer D, Sailasuta N, Sullivan EV, Pfefferbaum A. In vivo 2D J-resolved magnetic resonance spectroscopy of rat brain with a 3-T clinical human scanner. Neuroimage. 2004 May; 22(1):381-6.
    View in: PubMed
  43. Pfefferbaum A, Sullivan EV, Adalsteinsson E, Garrick T, Harper C. Postmortem MR imaging of formalin-fixed human brain. Neuroimage. 2004 Apr; 21(4):1585-95.
    View in: PubMed
  44. Kim DH, Adalsteinsson E, Spielman DM. Spiral readout gradients for the reduction of motion artifacts in chemical shift imaging. Magn Reson Med. 2004 Mar; 51(3):458-63.
    View in: PubMed
  45. Hunjan S, Adalsteinsson E, Kim DH, Harsh GR, Boyer AL, Spielman D, Xing L. Quality assurance of magnetic resonance spectroscopic imaging-derived metabolic data. Int J Radiat Oncol Biol Phys. 2003 Nov 15; 57(4):1159-73.
    View in: PubMed
  46. Adalsteinsson E, Langer-Gould A, Homer RJ, Rao A, Sullivan EV, Lima CA, Pfefferbaum A, Atlas SW. Gray matter N-acetyl aspartate deficits in secondary progressive but not relapsing-remitting multiple sclerosis. AJNR Am J Neuroradiol. 2003 Nov-Dec; 24(10):1941-5.
    View in: PubMed
  47. Pfefferbaum A, Adalsteinsson E, Sullivan EV. Replicability of diffusion tensor imaging measurements of fractional anisotropy and trace in brain. J Magn Reson Imaging. 2003 Oct; 18(4):427-33.
    View in: PubMed
  48. Kim DH, Adalsteinsson E, Spielman DM. Simple analytic variable density spiral design. Magn Reson Med. 2003 Jul; 50(1):214-9.
    View in: PubMed
  49. Harper C, Garrick T, Matsumoto I, Pfefferbaum A, Adalsteinsson E, Sullivan E, Dodd P, Lewohl J, Butterworth R. How important are brain banks for alcohol research? Alcohol Clin Exp Res. 2003 Feb; 27(2):310-23.
    View in: PubMed
  50. Nordahl TE, Salo R, Possin K, Gibson DR, Flynn N, Leamon M, Galloway GP, Pfefferbaum A, Spielman DM, Adalsteinsson E, Sullivan EV. Low N-acetyl-aspartate and high choline in the anterior cingulum of recently abstinent methamphetamine-dependent subjects: a preliminary proton MRS study. Magnetic resonance spectroscopy. Psychiatry Res. 2002 Nov 30; 116(1-2):43-52.
    View in: PubMed
  51. Xing L, Cotrutz C, Hunjan S, Boyer AL, Adalsteinsson E, Spielman D. Inverse planning for functional image-guided intensity-modulated radiation therapy. Phys Med Biol. 2002 Oct 21; 47(20):3567-78.
    View in: PubMed
  52. Kim DH, Adalsteinsson E, Glover GH, Spielman DM. Regularized higher-order in vivo shimming. Magn Reson Med. 2002 Oct; 48(4):715-22.
    View in: PubMed
  53. Sullivan EV, Pfefferbaum A, Adalsteinsson E, Swan GE, Carmelli D. Differential rates of regional brain change in callosal and ventricular size: a 4-year longitudinal MRI study of elderly men. Cereb Cortex. 2002 Apr; 12(4):438-45.
    View in: PubMed
  54. Sullivan EV, Adalsteinsson E, Spielman DM, Hurd RE, Pfefferbaum A. N-acetylaspartate--a marker of neuronal integrity. Ann Neurol. 2001 Dec; 50(6):823; author reply 824-5.
    View in: PubMed
  55. Sullivan EV, Adalsteinsson E, Hedehus M, Ju C, Moseley M, Lim KO, Pfefferbaum A. Equivalent disruption of regional white matter microstructure in ageing healthy men and women. Neuroreport. 2001 Jan 22; 12(1):99-104.
    View in: PubMed
  56. Pfefferbaum A, Sullivan EV, Hedehus M, Adalsteinsson E, Lim KO, Moseley M. In vivo detection and functional correlates of white matter microstructural disruption in chronic alcoholism. Alcohol Clin Exp Res. 2000 Aug; 24(8):1214-21.
    View in: PubMed
  57. Pfefferbaum A, Sullivan EV, Hedehus M, Lim KO, Adalsteinsson E, Moseley M. Age-related decline in brain white matter anisotropy measured with spatially corrected echo-planar diffusion tensor imaging. Magn Reson Med. 2000 Aug; 44(2):259-68.
    View in: PubMed
  58. Hanson LG, Adalsteinsson E, Pfefferbaum A, Spielman DM. Optimal voxel size for measuring global gray and white matter proton metabolite concentrations using chemical shift imaging. Magn Reson Med. 2000 Jul; 44(1):10-8.
    View in: PubMed
  59. Adalsteinsson E, Sullivan EV, Kleinhans N, Spielman DM, Pfefferbaum A. Longitudinal decline of the neuronal marker N-acetyl aspartate in Alzheimer's disease. Lancet. 2000 May 13; 355(9216):1696-7.
    View in: PubMed
  60. Winsberg ME, Sachs N, Tate DL, Adalsteinsson E, Spielman D, Ketter TA. Decreased dorsolateral prefrontal N-acetyl aspartate in bipolar disorder. Biol Psychiatry. 2000 Mar 15; 47(6):475-81.
    View in: PubMed
  61. Star-Lack JM, Adalsteinsson E, Gold GE, Ikeda DM, Spielman DM. Motion correction and lipid suppression for 1H magnetic resonance spectroscopy. Magn Reson Med. 2000 Mar; 43(3):325-30.
    View in: PubMed
  62. Star-Lack JM, Adalsteinsson E, Adam MF, Terris DJ, Pinto HA, Brown JM, Spielman DM. In vivo 1H MR spectroscopy of human head and neck lymph node metastasis and comparison with oxygen tension measurements. AJNR Am J Neuroradiol. 2000 Jan; 21(1):183-93.
    View in: PubMed
  63. Adalsteinsson E, Star-Lack J, Meyer CH, Spielman DM. Reduced spatial side lobes in chemical-shift imaging. Magn Reson Med. 1999 Aug; 42(2):314-23.
    View in: PubMed
  64. Pfefferbaum A, Adalsteinsson E, Spielman D, Sullivan EV, Lim KO. In vivo spectroscopic quantification of the N-acetyl moiety, creatine, and choline from large volumes of brain gray and white matter: effects of normal aging. Magn Reson Med. 1999 Feb; 41(2):276-84.
    View in: PubMed
  65. Pfefferbaum A, Adalsteinsson E, Spielman D, Sullivan EV, Lim KO. In vivo brain concentrations of N-acetyl compounds, creatine, and choline in Alzheimer disease. Arch Gen Psychiatry. 1999 Feb; 56(2):185-92.
    View in: PubMed
  66. Adalsteinsson E, Spielman DM. Spatially resolved two-dimensional spectroscopy. Magn Reson Med. 1999 Jan; 41(1):8-12.
    View in: PubMed
  67. Adalsteinsson E, Spielman DM, Pauly JM, Terris DJ, Sommer G, Macovski A. Feasibility study of lactate imaging of head and neck tumors. NMR Biomed. 1998 Nov; 11(7):360-9.
    View in: PubMed
  68. Spielman DM, Adalsteinsson E, Lim KO. Quantitative assessment of improved homogeneity using higher-order shims for spectroscopic imaging of the brain. Magn Reson Med. 1998 Sep; 40(3):376-82.
    View in: PubMed
  69. Star-Lack J, Spielman D, Adalsteinsson E, Kurhanewicz J, Terris DJ, Vigneron DB. In vivo lactate editing with simultaneous detection of choline, creatine, NAA, and lipid singlets at 1.5 T using PRESS excitation with applications to the study of brain and head and neck tumors. J Magn Reson. 1998 Aug; 133(2):243-54.
    View in: PubMed
  70. Adalsteinsson E, Irarrazabal P, Topp S, Meyer C, Macovski A, Spielman DM. Volumetric spectroscopic imaging with spiral-based k-space trajectories. Magn Reson Med. 1998 Jun; 39(6):889-98.
    View in: PubMed
  71. Lim KO, Adalsteinsson E, Spielman D, Sullivan EV, Rosenbloom MJ, Pfefferbaum A. Proton magnetic resonance spectroscopic imaging of cortical gray and white matter in schizophrenia. Arch Gen Psychiatry. 1998 Apr; 55(4):346-52.
    View in: PubMed
  72. Clark JM, Marks MP, Adalsteinsson E, Spielman DM, Shuster D, Horoupian D, Albers GW. MELAS: Clinical and pathologic correlations with MRI, xenon/CT, and MR spectroscopy. Neurology. 1996 Jan; 46(1):223-7.
    View in: PubMed
  73. Adalsteinsson E, Irarrazabal P, Spielman DM, Macovski A. Three-dimensional spectroscopic imaging with time-varying gradients. Magn Reson Med. 1995 Apr; 33(4):461-6.
    View in: PubMed
  74. Adalsteinsson E, Spielman DM, Wright GA, Pauly JM, Meyer CH, Macovski A. Incorporating lactate/lipid discrimination into a spectroscopic imaging sequence. Magn Reson Med. 1993 Jul; 30(1):124-30.
    View in: PubMed
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