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Ona Wu, Ph.D.

TitleAssociate Professor of Radiology
InstitutionMassachusetts General Hospital
DepartmentRadiology
AddressMassachusetts General Hospital
Room 2301
149 13th Street
Charlestown MA 02129

 Bibliographic 
 selected publications
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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  1. Edlow BL, Giacino JT, Hirschberg RE, Gerrard J, Wu O, Hochberg LR. Unexpected recovery of function after severe traumatic brain injury: the limits of early neuroimaging-based outcome prediction. Neurocrit Care. 2013 Dec; 19(3):364-75.
    View in: PubMed
  2. Meschia JF, Arnett DK, Ay H, Brown RD, Benavente OR, Cole JW, de Bakker PI, Dichgans M, Doheny KF, Fornage M, Grewal RP, Gwinn K, Jern C, Conde JJ, Johnson JA, Jood K, Laurie CC, Lee JM, Lindgren A, Markus HS, McArdle PF, McClure LA, Mitchell BD, Schmidt R, Rexrode KM, Rich SS, Rosand J, Rothwell PM, Rundek T, Sacco RL, Sharma P, Shuldiner AR, Slowik A, Wassertheil-Smoller S, Sudlow C, Thijs VN, Woo D, Worrall BB, Wu O, Kittner SJ. Stroke Genetics Network (SiGN) Study: Design and Rationale for a Genome-Wide Association Study of Ischemic Stroke Subtypes. Stroke. 2013 Oct; 44(10):2694-702.
    View in: PubMed
  3. Edlow BL, Giacino JT, Wu O. Functional MRI and outcome in traumatic coma. Curr Neurol Neurosci Rep. 2013 Sep; 13(9):375.
    View in: PubMed
  4. Greer DM, Yang J, Scripko PD, Sims JR, Cash S, Wu O, Hafler JP, Schoenfeld DA, Furie KL. Clinical examination for prognostication in comatose cardiac arrest patients. Resuscitation. 2013 Nov; 84(11):1546-51.
    View in: PubMed
  5. Wintermark M, Albers GW, Broderick JP, Demchuk AM, Fiebach JB, Fiehler J, Grotta JC, Houser G, Jovin TG, Lees KR, Lev MH, Liebeskind DS, Luby M, Muir KW, Parsons MW, von Kummer R, Wardlaw JM, Wu O, Yoo AJ, Alexandrov AV, Alger JR, Aviv RI, Bammer R, Baron JC, Calamante F, Campbell BC, Carpenter TC, Christensen S, Copen WA, Derdeyn CP, Haley EC, Khatri P, Kudo K, Lansberg MG, Latour LL, Lee TY, Leigh R, Lin W, Lyden P, Mair G, Menon BK, Michel P, Mikulik R, Nogueira RG, Ostergaard L, Pedraza S, Riedel CH, Rowley HA, Sanelli PC, Sasaki M, Saver JL, Schaefer PW, Schellinger PD, Tsivgoulis G, Wechsler LR, White PM, Zaharchuk G, Zaidat OO, Davis SM, Donnan GA, Furlan AJ, Hacke W, Kang DW, Kidwell C, Thijs VN, Thomalla G, Warach SJ. Acute Stroke Imaging Research Roadmap II. Stroke. 2013 Sep; 44(9):2628-39.
    View in: PubMed
  6. Edlow BL, Haynes RL, Takahashi E, Klein JP, Cummings P, Benner T, Greer DM, Greenberg SM, Wu O, Kinney HC, Folkerth RD. Disconnection of the ascending arousal system in traumatic coma. J Neuropathol Exp Neurol. 2013 Jun; 72(6):505-23.
    View in: PubMed
  7. Bouts MJ, Tiebosch IA, van der Toorn A, Viergever MA, Wu O, Dijkhuizen RM. Early identification of potentially salvageable tissue with MRI-based predictive algorithms after experimental ischemic stroke. J Cereb Blood Flow Metab. 2013 Jul; 33(7):1075-82.
    View in: PubMed
  8. Edlow BL, Wu O. Advanced neuroimaging in traumatic brain injury. Semin Neurol. 2012 Sep; 32(4):374-400.
    View in: PubMed
  9. Cheng B, Brinkmann M, Forkert ND, Treszl A, Ebinger M, Köhrmann M, Wu O, Kang DW, Liebeskind DS, Tourdias T, Singer OC, Christensen S, Luby M, Warach S, Fiehler J, Fiebach JB, Gerloff C, Thomalla G. Quantitative measurements of relative fluid-attenuated inversion recovery (FLAIR) signal intensities in acute stroke for the prediction of time from symptom onset. J Cereb Blood Flow Metab. 2013 Jan; 33(1):76-84.
    View in: PubMed
  10. Greer DM, Scripko PD, Wu O, Edlow BL, Bartscher J, Sims JR, Camargo EE, Singhal AB, Furie KL. Hippocampal Magnetic Resonance Imaging Abnormalities in Cardiac Arrest are Associated with Poor Outcome. J Stroke Cerebrovasc Dis. 2013 Oct; 22(7):899-905.
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  11. Cheng B, Ebinger M, Kufner A, Köhrmann M, Wu O, Kang DW, Liebeskind D, Tourdias T, Singer OC, Christensen S, Warach S, Luby M, Fiebach JB, Fiehler J, Gerloff C, Thomalla G. Hyperintense vessels on acute stroke fluid-attenuated inversion recovery imaging: associations with clinical and other MRI findings. Stroke. 2012 Nov; 43(11):2957-61.
    View in: PubMed
  12. Deipolyi AR, Wu O, Macklin EA, Schaefer PW, Schwamm LH, Gilberto Gonzalez R, Copen WA. Reliability of cerebral blood volume maps as a substitute for diffusion-weighted imaging in acute ischemic stroke. J Magn Reson Imaging. 2012 Nov; 36(5):1083-7.
    View in: PubMed
  13. Wu O, Lu J, Mandeville JB, Murata Y, Egi Y, Dai G, Marota JJ, Diwan I, Dijkhuizen RM, Kwong KK, Lo EH, Singhal AB. Dynamic functional cerebral blood volume responses to normobaric hyperoxia in acute ischemic stroke. J Cereb Blood Flow Metab. 2012 Sep; 32(9):1800-9.
    View in: PubMed
  14. Song SS, Latour LL, Ritter CH, Wu O, Tighiouart M, Hernandez DA, Ku KD, Luby M, Warach S. A pragmatic approach using magnetic resonance imaging to treat ischemic strokes of unknown onset time in a thrombolytic trial. Stroke. 2012 Sep; 43(9):2331-5.
    View in: PubMed
  15. Edlow BL, Takahashi E, Wu O, Benner T, Dai G, Bu L, Grant PE, Greer DM, Greenberg SM, Kinney HC, Folkerth RD. Neuroanatomic connectivity of the human ascending arousal system critical to consciousness and its disorders. J Neuropathol Exp Neurol. 2012 Jun; 71(6):531-46.
    View in: PubMed
  16. Greer DM, Yang J, Scripko PD, Sims JR, Cash S, Kilbride R, Wu O, Hafler JP, Schoenfeld DA, Furie KL. Clinical examination for outcome prediction in nontraumatic coma. Crit Care Med. 2012 Apr; 40(4):1150-6.
    View in: PubMed
  17. Wu O, Benner T, Roccatagliata L, Zhu M, Schaefer PW, Sorensen AG, Singhal AB. Evaluating effects of normobaric oxygen therapy in acute stroke with MRI-based predictive models. Med Gas Res. 2012; 2(1):5.
    View in: PubMed
  18. Arkink EB, Bleeker EJ, Schmitz N, Schoonman GG, Wu O, Ferrari MD, van Buchem MA, van Osch MJ, Kruit MC. Cerebral perfusion changes in migraineurs: a voxelwise comparison of interictal dynamic susceptibility contrast MRI measurements. Cephalalgia. 2012 Mar; 32(4):279-88.
    View in: PubMed
  19. Thomalla G, Cheng B, Ebinger M, Hao Q, Tourdias T, Wu O, Kim JS, Breuer L, Singer OC, Warach S, Christensen S, Treszl A, Forkert ND, Galinovic I, Rosenkranz M, Engelhorn T, Köhrmann M, Endres M, Kang DW, Dousset V, Sorensen AG, Liebeskind DS, Fiebach JB, Fiehler J, Gerloff C. DWI-FLAIR mismatch for the identification of patients with acute ischaemic stroke within 4·5 h of symptom onset (PRE-FLAIR): a multicentre observational study. Lancet Neurol. 2011 Nov; 10(11):978-86.
    View in: PubMed
  20. Kimberly WT, Wu O, Arsava EM, Garg P, Ji R, Vangel M, Singhal AB, Ay H, Sorensen AG. Lower hemoglobin correlates with larger stroke volumes in acute ischemic stroke. Cerebrovasc Dis Extra. 2011 Jan-Dec; 1(1):44-53.
    View in: PubMed
  21. Kwong KK, Wu O, Chan ST, Nelissen K, Kholodov M, Chesler DA. Early time points perfusion imaging: relative time of arrival, maximum derivatives and fractional derivatives. Neuroimage. 2011 Aug 1; 57(3):979-90.
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  22. Copen WA, Schaefer PW, Wu O. MR perfusion imaging in acute ischemic stroke. Neuroimaging Clin N Am. 2011 May; 21(2):259-83, x.
    View in: PubMed
  23. Wu O, Schwamm LH, Sorensen AG. Imaging stroke patients with unclear onset times. Neuroimaging Clin N Am. 2011 May; 21(2):327-44, xi.
    View in: PubMed
  24. Wu O, Batista LM, Lima FO, Vangel MG, Furie KL, Greer DM. Predicting clinical outcome in comatose cardiac arrest patients using early noncontrast computed tomography. Stroke. 2011 Apr; 42(4):985-92.
    View in: PubMed
  25. Gokcay F, Arsava EM, Baykaner T, Vangel M, Garg P, Wu O, Singhal AB, Furie KL, Sorensen AG, Ay H. Age-dependent susceptibility to infarct growth in women. Stroke. 2011 Apr; 42(4):947-51.
    View in: PubMed
  26. Kwong KK, Reese TG, Nelissen K, Wu O, Chan ST, Benner T, Mandeville JB, Foley M, Vanduffel W, Chesler DA. Early time points perfusion imaging. Neuroimage. 2011 Jan 15; 54(2):1070-82.
    View in: PubMed
  27. Emmer BJ, van Osch MJ, Wu O, Steup-Beekman GM, Steens SC, Huizinga TW, van Buchem MA, van der Grond J. Perfusion MRI in neuro-psychiatric systemic lupus erthemathosus. J Magn Reson Imaging. 2010 Aug; 32(2):283-8.
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  28. Wu O, Dijkhuizen RM, Sorensen AG. Multiparametric magnetic resonance imaging of brain disorders. Top Magn Reson Imaging. 2010 Apr; 21(2):129-38.
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  29. Fujiwara N, Murata Y, Arai K, Egi Y, Lu J, Wu O, Singhal AB, Lo EH. Combination therapy with normobaric oxygen (NBO) plus thrombolysis in experimental ischemic stroke. BMC Neurosci. 2009; 10:79.
    View in: PubMed
  30. Wu O, Sorensen AG, Benner T, Singhal AB, Furie KL, Greer DM. Comatose patients with cardiac arrest: predicting clinical outcome with diffusion-weighted MR imaging. Radiology. 2009 Jul; 252(1):173-81.
    View in: PubMed
  31. Christensen S, Mouridsen K, Wu O, Hjort N, Karstoft H, Thomalla G, Röther J, Fiehler J, Kucinski T, Østergaard L. Comparison of 10 perfusion MRI parameters in 97 sub-6-hour stroke patients using voxel-based receiver operating characteristics analysis. Stroke. 2009 Jun; 40(6):2055-61.
    View in: PubMed
  32. Copen WA, Rezai Gharai L, Barak ER, Schwamm LH, Wu O, Kamalian S, Gonzalez RG, Schaefer PW. Existence of the diffusion-perfusion mismatch within 24 hours after onset of acute stroke: dependence on proximal arterial occlusion. Radiology. 2009 Mar; 250(3):878-86.
    View in: PubMed
  33. Christensen S, Calamante F, Hjort N, Wu O, Blankholm AD, Desmond P, Davis S, Ostergaard L. Inferring origin of vascular supply from tracer arrival timing patterns using bolus tracking MRI. J Magn Reson Imaging. 2008 Jun; 27(6):1371-81.
    View in: PubMed
  34. Wintermark M, Albers GW, Alexandrov AV, Alger JR, Bammer R, Baron JC, Davis S, Demaerschalk BM, Derdeyn CP, Donnan GA, Eastwood JD, Fiebach JB, Fisher M, Furie KL, Goldmakher GV, Hacke W, Kidwell CS, Kloska SP, Köhrmann M, Koroshetz W, Lee TY, Lees KR, Lev MH, Liebeskind DS, Ostergaard L, Powers WJ, Provenzale J, Schellinger P, Silbergleit R, Sorensen AG, Wardlaw J, Wu O, Warach S. Acute stroke imaging research roadmap. AJNR Am J Neuroradiol. 2008 May; 29(5):e23-30.
    View in: PubMed
  35. Wintermark M, Albers GW, Alexandrov AV, Alger JR, Bammer R, Baron JC, Davis S, Demaerschalk BM, Derdeyn CP, Donnan GA, Eastwood JD, Fiebach JB, Fisher M, Furie KL, Goldmakher GV, Hacke W, Kidwell CS, Kloska SP, Köhrmann M, Koroshetz W, Lee TY, Lees KR, Lev MH, Liebeskind DS, Ostergaard L, Powers WJ, Provenzale J, Schellinger P, Silbergleit R, Sorensen AG, Wardlaw J, Wu O, Warach S. Acute stroke imaging research roadmap. Stroke. 2008 May; 39(5):1621-8.
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  36. Ay H, Arsava EM, Rosand J, Furie KL, Singhal AB, Schaefer PW, Wu O, Gonzalez RG, Koroshetz WJ, Sorensen AG. Severity of leukoaraiosis and susceptibility to infarct growth in acute stroke. Stroke. 2008 May; 39(5):1409-13.
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  37. Ay H, Arsava EM, Vangel M, Oner B, Zhu M, Wu O, Singhal A, Koroshetz WJ, Sorensen AG. Interexaminer difference in infarct volume measurements on MRI: a source of variance in stroke research. Stroke. 2008 Apr; 39(4):1171-6.
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  38. Hjort N, Wu O, Ashkanian M, Sølling C, Mouridsen K, Christensen S, Gyldensted C, Andersen G, Østergaard L. MRI detection of early blood-brain barrier disruption: parenchymal enhancement predicts focal hemorrhagic transformation after thrombolysis. Stroke. 2008 Mar; 39(3):1025-8.
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  39. van der Zijden JP, Bouts MJ, Wu O, Roeling TA, Bleys RL, van der Toorn A, Dijkhuizen RM. Manganese-enhanced MRI of brain plasticity in relation to functional recovery after experimental stroke. J Cereb Blood Flow Metab. 2008 Apr; 28(4):832-40.
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  40. Wu O, Singhal AB, Benner T, Roccotagliata L, Zhu M, Schaefer PW, Ay H, Arsava EM, Cacciola J, Melinosky C, Gonzalez RG, Koroshetz WJ, Sorensen AG. Applying MRI-based multiparametric algorithms to randomized placebo-controlled pilot trial of normobaric oxygen therapy. Proceedings of the ISMRM 15th Scientific Meeting. 2007.
  41. Wu O, Ay H, Koroshetz WJ, Gonzalez RG, Arsava EM, Benner T, Cacciola J, Melinosky C, Singhal AB, Zhu M, Sorensen AG. Predicting tissue outcome using multiparametric algorithms that combine the four Ps of acute stroke imaging: parenchyma, pipes, perfusion and penumbra. Proceedings of the ISMRM 15th Scientific Meeting. 2007.
  42. van der Zijden JP, Wu O, van der Toorn A, Roeling TP, Bleys RL, Dijkhuizen RM. Changes in neuronal connectivity after stroke in rats as studied by serial manganese-enhanced MRI. Neuroimage. 2007 Feb 15; 34(4):1650-7.
    View in: PubMed
  43. Makris N, Papadimitriou GM, van der Kouwe A, Kennedy DN, Hodge SM, Dale AM, Benner T, Wald LL, Wu O, Tuch DS, Caviness VS, Moore TL, Killiany RJ, Moss MB, Rosene DL. Frontal connections and cognitive changes in normal aging rhesus monkeys: a DTI study. Neurobiol Aging. 2007 Oct; 28(10):1556-67.
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  44. Wu O, Christensen S, Hjort N, Dijkhuizen RM, Kucinski T, Fiehler J, Thomalla G, Röther J, Østergaard L. Characterizing physiological heterogeneity of infarction risk in acute human ischaemic stroke using MRI. Brain. 2006 Sep; 129(Pt 9):2384-93.
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  45. Wu O, Sumii T, Asahi M, Sasamata M, Ostergaard L, Rosen BR, Lo EH, Dijkhuizen RM. Infarct prediction and treatment assessment with MRI-based algorithms in experimental stroke models. J Cereb Blood Flow Metab. 2007 Jan; 27(1):196-204.
    View in: PubMed
  46. van der Zijden J, Wu O, van der Toorn A, Dijkhuizen RM. Early disturbance and subsequent reorganization of neuronal connectivity as studied with manganese-enhanced MRI after stroke in rats. Proceedings of the ISMRM 14th Scientific Meeting. 2006.
  47. Wu O, Schwamm LH, Koroshetz WJ, Benner T, Copen WA, Gonzalez RG, Sorensen AG. Predicting tissue outcome in acute human stroke using temporally adaptive MRI-based algorithms. Proceedings of the ISMRM 14th Scientific Meeting. 2006.
  48. Zhang WT, Mainero C, Wu O, Sorensen AG. Reproducibility of dynamic susceptibility contrast MR with standard and block-circulant deconvolution matrix. Proceedings of the ISMRM 14th Scientific Meeting. 2006.
  49. Christensen S, Wu O, Karstoft H, Hjort N, Butcher K, Davis S, Østergaard L. The physiological significance of the Tmax parameter in bolus tracking MRI. Proceedings of the ISMRM 14th Scientific Meeting. 2006.
  50. Emmer BJ, van Osch MJP, van As D, Wu O, Steup-Beekman GM, Steens SC, Huizinga TW, van Buchem MA, van der Grond J. . Perfusion weighted MR in NPSLE. Proceedings of the ISMRM 14th Scientific Meeting. 2006.
  51. Wu O, Koroshetz WJ, Gonzalez RG, Benner T, Lopez CJ, Zhu M, Cacciola J, Melinosky C, Ay H, Singhal AB, Sorensen AG. Effects of MR perfusion parameters selection on the prediction of tissue infarction in acute human stroke. Proceedings of the ISMRM 14th Scientific Meeting. 2006.
  52. Gregory A. Sorensen and Ona Wu. METHOD FOR EVALUATING NOVEL, STROKE TREATMENTS USING A TISSUE RISK MAP. 2006.
  53. Hjort N, Wu O, Ashkanian M, Solling C, Fiehler J, Thomalla G, Kucinski T, Rother J, Andersen G, Ostergaard L. Are MRI-based predictive models comparable among stroke centers?. Stroke. 2006; 37(1):703.
  54. Hjort N, Christensen S, Sølling C, Ashkanian M, Wu O, Røhl L, Gyldensted C, Andersen G, Østergaard L. Ischemic injury detected by diffusion imaging 11 minutes after stroke. Ann Neurol. 2005 Sep; 58(3):462-5.
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  55. Wu O, Ostergaard L, Sorensen AG. Technical aspects of perfusion-weighted imaging. Neuroimaging Clin N Am. 2005 Aug; 15(3):623-37, xi.
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  56. Wu O, Christensen S, Hjort N, Rosa-Neto P, Mouridsen K, Rodell A, et al. Predicting Tissue Infarction Using Acute MR Imaging in Stroke Patients Treated with Thrombolytic Therapy. Proceedings of the ISMRM 13th Scientific Meeting. 2005.
  57. Wu O, Sumii T, Sasamata M, Rosen BR, Lo EH, Dijkhuizen RM. Predicting Tissue Infarction Using Acute MR Imaging in Stroke Effect of occlusion duration on risk of infarction in a rat embolic stroke model studied with serial MRI-based predictive algorithms. Proceedings of the ISMRM 13th Scientific Meeting. 2005.
  58. Ay H, Koroshetz WJ, Benner T, Vangel MG, Wu O, Schwamm LH, Sorensen AG. Transient ischemic attack with infarction: a unique syndrome? Ann Neurol. 2005 May; 57(5):679-86.
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  59. Gottrup C, Thomsen K, Locht P, Wu O, Sorensen AG, Koroshetz WJ, Østergaard L. Applying instance-based techniques to prediction of final outcome in acute stroke. Artif Intell Med. 2005 Mar; 33(3):223-36.
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  60. Wu O, Hoogveld E, van der Toorn A, Dijkhuizen RM. Acute multiparametric MRI-based algorithms accurately predict chronic infarction in a rat stroke model. Stroke. 2005; 36(1):468.
  61. van Eijsden P, Notenboom RG, Wu O, de Graan PN, van Nieuwenhuizen O, Nicolay K, Braun KP. In vivo 1H magnetic resonance spectroscopy, T2-weighted and diffusion-weighted MRI during lithium-pilocarpine-induced status epilepticus in the rat. Brain Res. 2004 Dec 24; 1030(1):11-8.
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  62. Hoff E, van Oostenbrugge R, van der Zijden J, Wu O, van der Toorn A, Steinbusch H, Duikhuizen RM. . Mapping of cholinergic muscarinic receptor activation with pharmacological MRI. Proceedings of the ISMRM Twelfth Scientific Meeting. 2004.
  63. Wu O, Christensen S, Rosa-Neto P, Hjort N, Rodell A, Dijkhuizen RM, Fiehler J, Rother J, Ostergaard L. Anatomy as a parameter in multiparametic MRI-based predictive algorithms. Proceedings of the ISMRM Twelfth Scientific Meeting. 2004.
  64. Mouridsen K, Wu O, Christensen S, Gottrup C, Koroshetz WJ, Sorensen AG, Østergaard L. Optimal Parameter Choice in Predicting Final Outcome in Acute Stroke. Proceedings of the ISMRM Twelfth Scientific Meeting. 2004.
  65. van der Zijden J, Hoogveld E, van der Toorn A, Wu O, Dijkhuizen RM. Mapping cortical projections after stroke in rat brain with in vivo manganese-enhanced MRI. Proceedings of the ISMRM Twelfth Scientific Meeting. 2004.
  66. Christensen S, Wu O, Mouridsen K, Gottrup C, Fiehler J, Rother J, Østergaard L. Local Arterial Input Functions based on Vascular Territories. Proceedings of the ISMRM Twelfth Scientific Meeting. 2004.
  67. Wu O, Koroshetz WJ, Ay H, O'Donnell J, Benner T, Ostergaard L, Lopez CJ, Zhu M, Dijkhuizen RM, Rosen BR, Sorensen AG. Comparison of CBF deconvolution techniques using bolus tracking in the presence of delayed tracer arrival in acute stroke patients. Proceedings of the ISMRM Twelfth Scientific Meeting. 2004.
  68. Ozsunar Y, Grant PE, Huisman TA, Schaefer PW, Wu O, Sorensen AG, Koroshetz WJ, Gonzalez RG. Evolution of water diffusion and anisotropy in hyperacute stroke: significant correlation between fractional anisotropy and T2. AJNR Am J Neuroradiol. 2004 May; 25(5):699-705.
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  69. Huisman TA, Schwamm LH, Schaefer PW, Koroshetz WJ, Shetty-Alva N, Ozsunar Y, Wu O, Sorensen AG. Diffusion tensor imaging as potential biomarker of white matter injury in diffuse axonal injury. AJNR Am J Neuroradiol. 2004 Mar; 25(3):370-6.
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  70. Wu O, Østergaard L, Koroshetz WJ, Schwamm LH, O'Donnell J, Schaefer PW, Rosen BR, Weisskoff RM, Sorensen AG. Effects of tracer arrival time on flow estimates in MR perfusion-weighted imaging. Magn Reson Med. 2003 Oct; 50(4):856-64.
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  71. van Osch MJ, Vonken EJ, Wu O, Viergever MA, van der Grond J, Bakker CJ. Model of the human vasculature for studying the influence of contrast injection speed on cerebral perfusion MRI. Magn Reson Med. 2003 Sep; 50(3):614-22.
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  72. Wu O, Østergaard L, Weisskoff RM, Benner T, Rosen BR, Sorensen AG. Tracer arrival timing-insensitive technique for estimating flow in MR perfusion-weighted imaging using singular value decomposition with a block-circulant deconvolution matrix. Magn Reson Med. 2003 Jul; 50(1):164-74.
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  73. Dijkhuizen RM, Singhal AB, Mandeville JB, Wu O, Halpern EF, Finklestein SP, Rosen BR, Lo EH. Correlation between brain reorganization, ischemic damage, and neurologic status after transient focal cerebral ischemia in rats: a functional magnetic resonance imaging study. J Neurosci. 2003 Jan 15; 23(2):510-7.
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  74. Dijkhuizen RM, Asahi M, Wu O, Rosen BR, Lo EH. Rapid breakdown of microvascular barriers and subsequent hemorrhagic transformation after delayed recombinant tissue plasminogen activator treatment in a rat embolic stroke model. Stroke. 2002 Aug; 33(8):2100-4.
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  75. Schaefer PW, Romero JM, Grant PE, Wu O, Sorensen AG, Koroshetz W, González RG. Perfusion magnetic resonance imaging of acute ischemic stroke. Semin Roentgenol. 2002 Jul; 37(3):230-6.
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  76. Schaefer PW, Romero JM, Grant PE, Wu O, Sorensen AG, Koroshetz W, González RG. Diffusion magnetic resonance imaging of acute ischemic stroke. Semin Roentgenol. 2002 Jul; 37(3):219-29.
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  77. Yamada K, Wu O, Gonzalez RG, Bakker D, Østergaard L, Copen WA, Weisskoff RM, Rosen BR, Yagi K, Nishimura T, Sorensen AG. Magnetic resonance perfusion-weighted imaging of acute cerebral infarction: effect of the calculation methods and underlying vasculopathy. Stroke. 2002 Jan; 33(1):87-94.
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  78. Wu O. Predictive Models of Tissue Outcome in Acute Human Cerebral Ischemia using Diffusion and Perfusion Weighted MRI. 2002.
  79. Makris N, Papadimitriou GM, Worth AJ, Jenkins BG, Garrido L, Sorensen AG, Wedeen VJ, Tuch DS, Wu O, Cudkowicz ME, Caviness VS Jr, Rosen BR, Kennedy DN. Diffusion Tensor Imaging. Neuropsychopharmacology; The Fifth Generation of Progress. 2002; 357-371.
  80. Dijkhuizen RM, Ren J, Mandeville JB, Wu O, Ozdag FM, Moskowitz MA, Rosen BR, Finklestein SP. Functional magnetic resonance imaging of reorganization in rat brain after stroke. Proc Natl Acad Sci U S A. 2001 Oct 23; 98(22):12766-71.
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  81. Grant PE, He J, Halpern EF, Wu O, Schaefer PW, Schwamm LH, Budzik RF, Sorensen AG, Koroshetz WJ, Gonzalez RG. Frequency and clinical context of decreased apparent diffusion coefficient reversal in the human brain. Radiology. 2001 Oct; 221(1):43-50.
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  82. Copen WA, Schwamm LH, González RG, Wu O, Harmath CB, Schaefer PW, Koroshetz WJ, Sorensen AG. Ischemic stroke: effects of etiology and patient age on the time course of the core apparent diffusion coefficient. Radiology. 2001 Oct; 221(1):27-34.
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  83. Dijkhuizen RM, Asahi M, Wu O, Rosen BR, Lo EH. Delayed rt-PA treatment in a rat embolic stroke model: diagnosis and prognosis of ischemic injury and hemorrhagic transformation with magnetic resonance imaging. J Cereb Blood Flow Metab. 2001 Aug; 21(8):964-71.
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  84. Yoshiura T, Wu O, Zaheer A, Reese TG, Sorensen AG. Highly diffusion-sensitized MRI of brain: dissociation of gray and white matter. Magn Reson Med. 2001 May; 45(5):734-40.
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  85. Hadjikhani N, Sanchez Del Rio M, Wu O, Schwartz D, Bakker D, Fischl B, Kwong KK, Cutrer FM, Rosen BR, Tootell RB, Sorensen AG, Moskowitz MA. Mechanisms of migraine aura revealed by functional MRI in human visual cortex. Proc Natl Acad Sci U S A. 2001 Apr 10; 98(8):4687-92.
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  86. Wu O, Koroshetz WJ, Ostergaard L, Buonanno FS, Copen WA, Gonzalez RG, Rordorf G, Rosen BR, Schwamm LH, Weisskoff RM, Sorensen AG. Predicting tissue outcome in acute human cerebral ischemia using combined diffusion- and perfusion-weighted MR imaging. Stroke. 2001 Apr; 32(4):933-42.
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  87. Ostergaard L, Sorensen AG, Chesler DA, Weisskoff RM, Koroshetz WJ, Wu O, Gyldensted C, Rosen BR. Combined diffusion-weighted and perfusion-weighted flow heterogeneity magnetic resonance imaging in acute stroke. Stroke. 2000 May; 31(5):1097-103.
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  88. Sanchez del Rio M, Bakker D, Wu O, Agosti R, Mitsikostas DD, Ostergaard L, Wells WA, Rosen BR, Sorensen G, Moskowitz MA, Cutrer FM. Perfusion weighted imaging during migraine: spontaneous visual aura and headache. Cephalalgia. 1999 Oct; 19(8):701-7.
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  89. Sorensen AG, Wu O, Copen WA, Davis TL, Gonzalez RG, Koroshetz WJ, Reese TG, Rosen BR, Wedeen VJ, Weisskoff RM. Human acute cerebral ischemia: detection of changes in water diffusion anisotropy by using MR imaging. Radiology. 1999 Sep; 212(3):785-92.
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  90. Yoshiura T, Wu O, Sorensen AG. Advanced MR techniques: diffusion MR imaging, perfusion MR imaging, and spectroscopy. Neuroimaging Clin N Am. 1999 Aug; 9(3):439-53.
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  91. Ay H, Buonanno FS, Rordorf G, Schaefer PW, Schwamm LH, Wu O, Gonzalez RG, Yamada K, Sorensen GA, Koroshetz WJ. Normal diffusion-weighted MRI during stroke-like deficits. Neurology. 1999 Jun 10; 52(9):1784-92.
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  92. Makris N, Worth AJ, Sorensen AG, Papadimitriou GM, Wu O, Reese TG, Wedeen VJ, Davis TL, Stakes JW, Caviness VS, Kaplan E, Rosen BR, Pandya DN, Kennedy DN. Morphometry of in vivo human white matter association pathways with diffusion-weighted magnetic resonance imaging. Ann Neurol. 1997 Dec; 42(6):951-62.
    View in: PubMed
  93. Wu O. An Enhanced Reality System for the Great Outdoors. 1994.
  94. Wu O. Winning the Hearts and Minds of the Chinese People: A study of Japanese, American, Kuomintang and Communist Propaganda 1937-1945. 1992.
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