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Hemant S. Thatte, Ph.D.

TitleAssociate Professor of Surgery
InstitutionVeterans Affairs Boston Healthcare System
DepartmentSurgery
AddressVA Boston Healthcare System
Department of Surgery (MC112)
1400 VFW Pkwy
West Roxbury MA 02132
Phone857/203-5919
Fax857/203-5592

 Bibliographic 
 selected publications
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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  1. Lowalekar SK, Lu XG, Thatte HS. Further evaluation of somah: long-term preservation, temperature effect, and prevention of ischemia-reperfusion injury in rat hearts harvested after cardiocirculatory death. Transplant Proc. 2013 Nov; 45(9):3192-7.
    View in: PubMed
  2. Ng KK, Thatte HS, Spector M. Chondrogenic differentiation of adult mesenchymal stem cells and embryonic cells in collagen scaffolds. J Biomed Mater Res A. 2011 Nov; 99(2):275-82.
    View in: PubMed
  3. Hussaini BE, Lu XG, Wolfe JA, Thatte HS. Evaluation of endoscopic vein extraction on structural and functional viability of saphenous vein endothelium. J Cardiothorac Surg. 2011; 6:82.
    View in: PubMed
  4. Ikuta T, Thatte HS, Tang JX, Mukerji I, Knee K, Bridges KR, Wang S, Montero-Huerta P, Joshi RM, Head CA. Nitric oxide reduces sickle hemoglobin polymerization: potential role of nitric oxide-induced charge alteration in depolymerization. Arch Biochem Biophys. 2011 Jun 1; 510(1):53-61.
    View in: PubMed
  5. Hussaini BE, Thatte HS, Rhodes BA, Treanor PR, Birjiniuk V. Thromboresistant surfaces with low-dose anticoagulation alleviate clopidogrel-related complications in patients undergoing coronary artery bypass grafting. J Thorac Cardiovasc Surg. 2011 Mar; 141(3):782-8.
    View in: PubMed
  6. Hussaini BE, Treanor PR, Healey NA, Lu XG, Khuri SF, Thatte HS. Multifactorial comparison of modified and conventional perfusion strategies in a porcine model of cardiopulmonary bypass. J Surg Res. 2011 Jun 1; 168(1):e7-15.
    View in: PubMed
  7. Hussaini BE, Treanor PR, Healey NA, Tilahun D, Srey R, Lu XG, Khuri SF, Thatte HS. Evaluation of blood components exposed to coated arterial filters in extracorporeal circuits. Perfusion. 2009 Sep; 24(5):317-23.
    View in: PubMed
  8. Thatte HS, Rousou L, Hussaini BE, Lu XG, Treanor PR, Khuri SF. Development and evaluation of a novel solution, Somah, for the procurement and preservation of beating and nonbeating donor hearts for transplantation. Circulation. 2009 Oct 27; 120(17):1704-13.
    View in: PubMed
  9. Kumbhani DJ, Healey NA, Thatte HS, Birjiniuk V, Crittenden MD, Treanor PR, Khuri SF. Intraoperative myocardial acidosis as a risk for hospital readmission after cardiac surgery. Am J Surg. 2009 Sep; 198(3):373-80.
    View in: PubMed
  10. Thatte HS, He XD, Goyal RK. Imaging of nitric oxide in nitrergic neuromuscular neurotransmission in the gut. PLoS One. 2009; 4(4):e4990.
    View in: PubMed
  11. Rousou LJ, Taylor KB, Lu XG, Healey N, Crittenden MD, Khuri SF, Thatte HS. Saphenous vein conduits harvested by endoscopic technique exhibit structural and functional damage. Ann Thorac Surg. 2009 Jan; 87(1):62-70.
    View in: PubMed
  12. Rousou LJ, Crittenden MD, Taylor KB, Healey NA, Gibson S, Thatte HS, Haime M, Khuri SF. Troponin I after cardiac surgery and its implications on myocardial protection, outcomes, and cost. Am J Surg. 2008 Nov; 196(5):703-9.
    View in: PubMed
  13. Kabatas S, Yu D, He XD, Thatte HS, Benedict D, Hepgul KT, Black PM, Sabharwal S, Teng YD. Neural and anatomical abnormalities of the gastrointestinal system resulting from contusion spinal cord injury. Neuroscience. 2008 Jul 17; 154(4):1627-38.
    View in: PubMed
  14. Rao VS, Titushkin IA, Moros EG, Pickard WF, Thatte HS, Cho MR. Nonthermal effects of radiofrequency-field exposure on calcium dynamics in stem cell-derived neuronal cells: elucidation of calcium pathways. Radiat Res. 2008 Mar; 169(3):319-29.
    View in: PubMed
  15. Kumbhani DJ, Healey NA, Thatte HS, Nawas S, Crittenden MD, Birjiniuk V, Treanor PR, Khuri SF. Patients with diabetes mellitus undergoing cardiac surgery are at greater risk for developing intraoperative myocardial acidosis. J Thorac Cardiovasc Surg. 2007 Jun; 133(6):1566-72.
    View in: PubMed
  16. Ramesh V, Thatte HS, McCarley RW, Basheer R. Adenosine and sleep deprivation promote NF-kappaB nuclear translocation in cholinergic basal forebrain. J Neurochem. 2007 Mar; 100(5):1351-63.
    View in: PubMed
  17. Zhu DM, Dustin ML, Cairo CW, Thatte HS, Golan DE. Mechanisms of Cellular Avidity Regulation in CD2-CD58-Mediated T Cell Adhesion. ACS Chem Biol. 2006 Nov 21; 1(10):649-58.
    View in: PubMed
  18. Dygert JH, Thatte HS, Kumbhani DJ, Najjar SF, Treanor PR, Khuri SF. Intracoronary shunt-induced endothelial cell damage in porcine heart. J Surg Res. 2006 Apr; 131(2):168-74.
    View in: PubMed
  19. Thirunavukkarasu M, Penumathsa S, Juhasz B, Zhan L, Bagchi M, Yasmin T, Shara MA, Thatte HS, Bagchi D, Maulik N. Enhanced cardiovascular function and energy level by a novel chromium (III)-supplement. Biofactors. 2006; 27(1-4):53-67.
    View in: PubMed
  20. Prabhala RH, Neri P, Bae JE, Tassone P, Shammas MA, Allam CK, Daley JF, Chauhan D, Blanchard E, Thatte HS, Anderson KC, Munshi NC. Dysfunctional T regulatory cells in multiple myeloma. Blood. 2006 Jan 1; 107(1):301-4.
    View in: PubMed
  21. Fischer TH, Thatte HS, Nichols TC, Bender-Neal DE, Bellinger AD, Vournakis JN. Synergistic platelet integrin signaling and factor XII activation in poly-N-acetyl glucosamine fiber-mediated hemostasis. Biomaterials. 2005 Sep; 26(27):5433-43.
    View in: PubMed
  22. Thatte HS, Zagarins SE, Amiji M, Khuri SF. Poly-N-acetyl glucosamine-mediated red blood cell interactions. J Trauma. 2004 Jul; 57(1 Suppl):S7-12.
    View in: PubMed
  23. Najjar SF, Healey NA, Healey CM, McGarry T, Khan B, Thatte HS, Khuri SF. Evaluation of poly-N-acetyl glucosamine as a hemostatic agent in patients undergoing cardiac catheterization: a double-blind, randomized study. J Trauma. 2004 Jul; 57(1 Suppl):S38-41.
    View in: PubMed
  24. Thatte HS, Zagarins S, Khuri SF, Fischer TH. Mechanisms of poly-N-acetyl glucosamine polymer-mediated hemostasis: platelet interactions. J Trauma. 2004 Jul; 57(1 Suppl):S13-21.
    View in: PubMed
  25. Thatte HS, Rhee JH, Zagarins SE, Treanor PR, Birjiniuk V, Crittenden MD, Khuri SF. Acidosis-induced apoptosis in human and porcine heart. Ann Thorac Surg. 2004 Apr; 77(4):1376-83.
    View in: PubMed
  26. Fischer TH, Connolly R, Thatte HS, Schwaitzberg SS. Comparison of structural and hemostatic properties of the poly-N-acetyl glucosamine Syvek Patch with products containing chitosan. Microsc Res Tech. 2004 Feb 15; 63(3):168-74.
    View in: PubMed
  27. Thatte HS, Biswas KS, Najjar SF, Birjiniuk V, Crittenden MD, Michel T, Khuri SF. Multi-photon microscopic evaluation of saphenous vein endothelium and its preservation with a new solution, GALA. Ann Thorac Surg. 2003 Apr; 75(4):1145-52; discussion 1152.
    View in: PubMed
  28. Basheer R, Arrigoni E, Thatte HS, Greene RW, Ambudkar IS, McCarley RW. Adenosine induces inositol 1,4,5-trisphosphate receptor-mediated mobilization of intracellular calcium stores in basal forebrain cholinergic neurons. J Neurosci. 2002 Sep 1; 22(17):7680-6.
    View in: PubMed
  29. Cho MR, Marler JP, Thatte HS, Golan DE. Control of calcium entry in human fibroblasts by frequency-dependent electrical stimulation. Front Biosci. 2002 Jan 1; 7:a1-8.
    View in: PubMed
  30. Thatte HS, Khuri SF. The coronary artery bypass conduit: I. Intraoperative endothelial injury and its implication on graft patency. Ann Thorac Surg. 2001 Dec; 72(6):S2245-52; discussion S2267-70.
    View in: PubMed
  31. Sivarao DV, Mashimo HL, Thatte HS, Goyal RK. Lower esophageal sphincter is achalasic in nNOS(-/-) and hypotensive in W/W(v) mutant mice. Gastroenterology. 2001 Jul; 121(1):34-42.
    View in: PubMed
  32. Biswas KS, Thatte HS, Najjar SF, Rhee JH, Birjiniuk V, Crittenden MD, Michel T, Khuri SF. Multi-photon microscopy in the evaluation of human saphenous vein. J Surg Res. 2001 Jan; 95(1):37-43.
    View in: PubMed
  33. Cho MR, Thatte HS, Lee RC, Golan DE. Integrin-dependent human macrophage migration induced by oscillatory electrical stimulation. Ann Biomed Eng. 2000 Mar; 28(3):234-43.
    View in: PubMed
  34. Akbarali HI, Thatte H, He XD, Giles WR, Goyal RK. Role of HERG-like K(+) currents in opossum esophageal circular smooth muscle. Am J Physiol. 1999 Dec; 277(6 Pt 1):C1284-90.
    View in: PubMed
  35. Igarashi J, Thatte HS, Prabhakar P, Golan DE, Michel T. Calcium-independent activation of endothelial nitric oxide synthase by ceramide. Proc Natl Acad Sci U S A. 1999 Oct 26; 96(22):12583-8.
    View in: PubMed
  36. Leiter LM, Thatte HS, Okafor C, Marks PW, Golan DE, Bridges KR. Chloramphenicol-induced mitochondrial dysfunction is associated with decreased transferrin receptor expression and ferritin synthesis in K562 cells and is unrelated to IRE-IRP interactions. J Cell Physiol. 1999 Sep; 180(3):334-44.
    View in: PubMed
  37. Cho MR, Thatte HS, Silvia MT, Golan DE. Transmembrane calcium influx induced by ac electric fields. FASEB J. 1999 Apr; 13(6):677-83.
    View in: PubMed
  38. Goetz RM, Thatte HS, Prabhakar P, Cho MR, Michel T, Golan DE. Estradiol induces the calcium-dependent translocation of endothelial nitric oxide synthase. Proc Natl Acad Sci U S A. 1999 Mar 16; 96(6):2788-93.
    View in: PubMed
  39. Prabhakar P, Thatte HS, Goetz RM, Cho MR, Golan DE, Michel T. Receptor-regulated translocation of endothelial nitric-oxide synthase. J Biol Chem. 1998 Oct 16; 273(42):27383-8.
    View in: PubMed
  40. Cho MR, Thatte HS, Lee RC, Golan DE. Reorganization of microfilament structure induced by ac electric fields. FASEB J. 1996 Nov; 10(13):1552-8.
    View in: PubMed
  41. Golan DE, Corbett JD, Korsgren C, Thatte HS, Hayette S, Yawata Y, Cohen CM. Control of band 3 lateral and rotational mobility by band 4.2 in intact erythrocytes: release of band 3 oligomers from low-affinity binding sites. Biophys J. 1996 Mar; 70(3):1534-42.
    View in: PubMed
  42. Thatte HS, Bridges KR, Golan DE. ATP depletion causes translational immobilization of cell surface transferrin receptors in K562 cells. J Cell Physiol. 1996 Feb; 166(2):446-52.
    View in: PubMed
  43. Thatte HS, Bridges KR, Golan DE. Microtubule inhibitors differentially affect translational movement, cell surface expression, and endocytosis of transferrin receptors in K562 cells. J Cell Physiol. 1994 Aug; 160(2):345-57.
    View in: PubMed
  44. Cho MR, Thatte HS, Lee RC, Golan DE. Induced redistribution of cell surface receptors by alternating current electric fields. FASEB J. 1994 Jul; 8(10):771-6.
    View in: PubMed
  45. Goncalves E, Yamada K, Thatte HS, Backer JM, Golan DE, Kahn CR, Shoelson SE. Optimizing transmembrane domain helicity accelerates insulin receptor internalization and lateral mobility. Proc Natl Acad Sci U S A. 1993 Jun 15; 90(12):5762-6.
    View in: PubMed
  46. Thatte HS, Kasschau MR, Furlong ST, Byam-Smith MP, Williams DF, Golan DE. Schistosoma mansoni: membranes from adult worms reversibly perturb shape, volume, and membrane organization of intact human red blood cells. Exp Parasitol. 1993 Feb; 76(1):13-22.
    View in: PubMed
  47. Thatte HS, Schrier SL. Comparison of transferrin receptor-mediated endocytosis and drug-induced endocytosis in human neonatal and adult RBCs. Blood. 1988 Nov; 72(5):1693-700.
    View in: PubMed
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