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Last Name
Institution

David L. Pauls, PH.D.

TitleProfessor of Psychiatry
InstitutionMassachusetts General Hospital
DepartmentPsychiatry
AddressMassachusetts General Hospital
PNGU, CHGR, Simches 6th Floor
185 Cambridge St
Boston MA 02114
Phone617/726-0793
Fax617/726-0830
Other Positions
TitleProfessor in the Department of Epidemiology
InstitutionHarvard School of Public Health
DepartmentEpidemiology


 Bibliographic 
 selected publications
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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  1. Nag A, Bochukova EG, Kremeyer B, Campbell DD, Muller H, Valencia-Duarte AV, Cardona J, Rivas IC, Mesa SC, Cuartas M, Garcia J, Bedoya G, Cornejo W, Herrera LD, Romero R, Fournier E, Reus VI, Lowe TL, Farooqi IS, Mathews CA, McGrath LM, Yu D, Cook E, Wang K, Scharf JM, Pauls DL, Freimer NB, Plagnol V, Ruiz-Linares A. CNV Analysis in Tourette Syndrome Implicates Large Genomic Rearrangements in COL8A1 and NRXN1. PLoS One. 2013; 8(3):e59061.
    View in: PubMed
  2. Kuusikko-Gauffin S, Pollock-Wurman R, Mattila ML, Jussila K, Ebeling H, Pauls D, Moilanen I. Social anxiety in parents of high-functioning children with autism and asperger syndrome. J Autism Dev Disord. 2013 Mar; 43(3):521-9.
    View in: PubMed
  3. Egan CA, Marakovitz SE, O'Rourke JA, Osiecki L, Illmann C, Barton L, McLaughlin E, Proujansky R, Royal J, Cowley H, Rangel-Lugo M, Pauls DL, Scharf JM, Mathews CA. Effectiveness of a web-based protocol for the screening and phenotyping of individuals with Tourette syndrome for genetic studies. Am J Med Genet B Neuropsychiatr Genet. 2012 Dec; 159B(8):987-96.
    View in: PubMed
  4. Reich D, Patterson N, Campbell D, Tandon A, Mazieres S, Ray N, Parra MV, Rojas W, Duque C, Mesa N, García LF, Triana O, Blair S, Maestre A, Dib JC, Bravi CM, Bailliet G, Corach D, Hünemeier T, Bortolini MC, Salzano FM, Petzl-Erler ML, Acuña-Alonzo V, Aguilar-Salinas C, Canizales-Quinteros S, Tusié-Luna T, Riba L, Rodríguez-Cruz M, Lopez-Alarcón M, Coral-Vazquez R, Canto-Cetina T, Silva-Zolezzi I, Fernandez-Lopez JC, Contreras AV, Jimenez-Sanchez G, Gómez-Vázquez MJ, Molina J, Carracedo A, Salas A, Gallo C, Poletti G, Witonsky DB, Alkorta-Aranburu G, Sukernik RI, Osipova L, Fedorova SA, Vasquez R, Villena M, Moreau C, Barrantes R, Pauls D, Excoffier L, Bedoya G, Rothhammer F, Dugoujon JM, Larrouy G, Klitz W, Labuda D, Kidd J, Kidd K, Di Rienzo A, Freimer NB, Price AL, Ruiz-Linares A. Reconstructing Native American population history. Nature. 2012 Aug 16; 488(7411):370-4.
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  5. Egeland JA, Endicott J, Hostetter AM, Allen CR, Pauls DL, Shaw JA. A 16-Year Prospective Study of Prodromal Features Prior to BPI Onset in Well Amish Children. J Affect Disord. 2012 Dec 15; 142(1-3):186-92.
    View in: PubMed
  6. Lyall K, Pauls DL, Spiegelman D, Santangelo SL, Ascherio A. Fertility therapies, infertility and autism spectrum disorders in the Nurses' Health Study II. Paediatr Perinat Epidemiol. 2012 Jul; 26(4):361-72.
    View in: PubMed
  7. Rahko JS, Paakki JJ, Starck TH, Nikkinen J, Pauls DL, Kätsyri JV, Jansson-Verkasalo EM, Carter AS, Hurtig TM, Mattila ML, Jussila KK, Remes JJ, Kuusikko-Gauffin SA, Sams ME, Bölte S, Ebeling HE, Moilanen IK, Tervonen O, Kiviniemi V. Valence scaling of dynamic facial expressions is altered in high-functioning subjects with autism spectrum disorders: an fMRI study. J Autism Dev Disord. 2012 Jun; 42(6):1011-24.
    View in: PubMed
  8. Nestadt G, Wang Y, Grados MA, Riddle MA, Greenberg BD, Knowles JA, Fyer AJ, McCracken JT, Rauch SL, Murphy DL, Rasmussen SA, Cullen B, Piacentini J, Geller D, Pauls D, Bienvenu OJ, Chen Y, Liang KY, Goes FS, Maher B, Pulver AE, Shugart YY, Valle D, Samuels JF, Chang YC. Homeobox genes in obsessive-compulsive disorder. Am J Med Genet B Neuropsychiatr Genet. 2012 Jan; 159B(1):53-60.
    View in: PubMed
  9. Lyall K, Pauls DL, Spiegelman D, Ascherio A, Santangelo SL. Pregnancy complications and obstetric suboptimality in association with autism spectrum disorders in children of the Nurses' Health Study II. Autism Res. 2012 Feb; 5(1):21-30.
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  10. Lochner C, Stein DJ, Woods D, Pauls DL, Franklin ME, Loerke EH, Keuthen NJ. The validity of DSM-IV-TR criteria B and C of hair-pulling disorder (trichotillomania): evidence from a clinical study. Psychiatry Res. 2011 Sep 30; 189(2):276-80.
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  11. Stewart SE, Hu YP, Hezel DM, Proujansky R, Lamstein A, Walsh C, Ben-Joseph EP, Gironda C, Jenike M, Geller DA, Pauls DL. Development and psychometric properties of the OCD Family Functioning (OFF) Scale. J Fam Psychol. 2011 Jun; 25(3):434-43.
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  12. Bienvenu OJ, Samuels JF, Wuyek LA, Liang KY, Wang Y, Grados MA, Cullen BA, Riddle MA, Greenberg BD, Rasmussen SA, Fyer AJ, Pinto A, Rauch SL, Pauls DL, McCracken JT, Piacentini J, Murphy DL, Knowles JA, Nestadt G. Is obsessive-compulsive disorder an anxiety disorder, and what, if any, are spectrum conditions? A family study perspective. Psychol Med. 2012 Jan; 42(1):1-13.
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  13. O'Rourke JA, Scharf JM, Platko J, Stewart SE, Illmann C, Geller DA, King RA, Leckman JF, Pauls DL. The familial association of tourette's disorder and ADHD: the impact of OCD symptoms. Am J Med Genet B Neuropsychiatr Genet. 2011 Jul; 156B(5):553-60.
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  14. Lyall K, Pauls DL, Santangelo SL, Santangelo S, Spiegelman D, Ascherio A. Maternal early life factors associated with hormone levels and the risk of having a child with an autism spectrum disorder in the nurses health study II. J Autism Dev Disord. 2011 May; 41(5):618-27.
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  15. Samuels J, Wang Y, Riddle MA, Greenberg BD, Fyer AJ, McCracken JT, Rauch SL, Murphy DL, Grados MA, Knowles JA, Piacentini J, Cullen B, Bienvenu OJ, Rasmussen SA, Geller D, Pauls DL, Liang KY, Shugart YY, Nestadt G. Comprehensive family-based association study of the glutamate transporter gene SLC1A1 in obsessive-compulsive disorder. Am J Med Genet B Neuropsychiatr Genet. 2011 Jun; 156B(4):472-7.
    View in: PubMed
  16. Poelmans G, Pauls DL, Buitelaar JK, Franke B. Integrated genome-wide association study findings: identification of a neurodevelopmental network for attention deficit hyperactivity disorder. Am J Psychiatry. 2011 Apr; 168(4):365-77.
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  17. Mroczkowski MM, Goes FS, Riddle MA, Grados MA, Bienvenu OJ, Greenberg BD, Fyer AJ, McCracken JT, Rauch SL, Murphy DL, Knowles JA, Piacentini J, Cullen B, Rasmussen SA, Geller DA, Pauls DL, Liang KY, Nestadt G, Samuels JF. Separation anxiety disorder in OCD. Depress Anxiety. 2011 Mar; 28(3):256-62.
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  18. Tsatsanis KD, Noens IL, Illmann CL, Pauls DL, Volkmar FR, Schultz RT, Klin A. Managing complexity: impact of organization and processing style on nonverbal memory in autism spectrum disorders. J Autism Dev Disord. 2011 Feb; 41(2):135-47.
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  19. Chang SC, Pauls DL, Lange C, Sasanfar R, Santangelo SL. Common genetic variation in the GAD1 gene and the entire family of DLX homeobox genes and autism spectrum disorders. Am J Med Genet B Neuropsychiatr Genet. 2011 Mar; 156(2):233-9.
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  20. Crane J, Fagerness J, Osiecki L, Gunnell B, Stewart SE, Pauls DL, Scharf JM. Family-based genetic association study of DLGAP3 in Tourette Syndrome. Am J Med Genet B Neuropsychiatr Genet. 2011 Jan; 156B(1):108-14.
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  21. Poelmans G, Buitelaar JK, Pauls DL, Franke B. A theoretical molecular network for dyslexia: integrating available genetic findings. Mol Psychiatry. 2011 Apr; 16(4):365-82.
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  22. Mattila ML, Hurtig T, Haapsamo H, Jussila K, Kuusikko-Gauffin S, Kielinen M, Linna SL, Ebeling H, Bloigu R, Joskitt L, Pauls DL, Moilanen I. Comorbid psychiatric disorders associated with Asperger syndrome/high-functioning autism: a community- and clinic-based study. J Autism Dev Disord. 2010 Sep; 40(9):1080-93.
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  23. Britton JC, Rauch SL, Rosso IM, Killgore WD, Price LM, Ragan J, Chosak A, Hezel DM, Pine DS, Leibenluft E, Pauls DL, Jenike MA, Stewart SE. Cognitive inflexibility and frontal-cortical activation in pediatric obsessive-compulsive disorder. J Am Acad Child Adolesc Psychiatry. 2010 Sep; 49(9):944-53.
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  24. Rahko J, Paakki JJ, Starck T, Nikkinen J, Remes J, Hurtig T, Kuusikko-Gauffin S, Mattila ML, Jussila K, Jansson-Verkasalo E, Kätsyri J, Sams M, Pauls D, Ebeling H, Moilanen I, Tervonen O, Kiviniemi V. Functional mapping of dynamic happy and fearful facial expression processing in adolescents. Brain Imaging Behav. 2010 Jun; 4(2):164-76.
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  25. Ercan-Sencicek AG, Stillman AA, Ghosh AK, Bilguvar K, O'Roak BJ, Mason CE, Abbott T, Gupta A, King RA, Pauls DL, Tischfield JA, Heiman GA, Singer HS, Gilbert DL, Hoekstra PJ, Morgan TM, Loring E, Yasuno K, Fernandez T, Sanders S, Louvi A, Cho JH, Mane S, Colangelo CM, Biederer T, Lifton RP, Gunel M, State MW. L-histidine decarboxylase and Tourette's syndrome. N Engl J Med. 2010 May 20; 362(20):1901-8.
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  26. Sampaio AS, Fagerness J, Crane J, Leboyer M, Delorme R, Pauls DL, Stewart SE. Association between polymorphisms in GRIK2 gene and obsessive-compulsive disorder: a family-based study. CNS Neurosci Ther. 2011 Jun; 17(3):141-7.
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  27. Wang Y, Adamczyk A, Shugart YY, Samuels JF, Grados MA, Greenberg BD, Knowles JA, McCracken JT, Rauch SL, Murphy DL, Rasmussen SA, Cullen B, Pinto A, Fyer AJ, Piacentini J, Pauls DL, Bienvenu OJ, Riddle M, Liang KY, Valle D, Wang T, Nestadt G. A screen of SLC1A1 for OCD-related alleles. Am J Med Genet B Neuropsychiatr Genet. 2010 Mar 5; 153B(2):675-9.
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  28. Pauls DL. The genetics of obsessive-compulsive disorder: a review. Dialogues Clin Neurosci. 2010; 12(2):149-63.
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  29. Hurtig T, Kuusikko S, Mattila ML, Haapsamo H, Ebeling H, Jussila K, Joskitt L, Pauls D, Moilanen I. Multi-informant reports of psychiatric symptoms among high-functioning adolescents with Asperger syndrome or autism. Autism. 2009 Nov; 13(6):583-98.
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  30. Voyiaziakis E, Evgrafov O, Li D, Yoon HJ, Tabares P, Samuels J, Wang Y, Riddle MA, Grados MA, Bienvenu OJ, Shugart YY, Liang KY, Greenberg BD, Rasmussen SA, Murphy DL, Wendland JR, McCracken JT, Piacentini J, Rauch SL, Pauls DL, Nestadt G, Fyer AJ, Knowles JA. Association of SLC6A4 variants with obsessive-compulsive disorder in a large multicenter US family study. Mol Psychiatry. 2011 Jan; 16(1):108-20.
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  31. Novak CE, Keuthen NJ, Stewart SE, Pauls DL. A twin concordance study of trichotillomania. Am J Med Genet B Neuropsychiatr Genet. 2009 Oct 5; 150B(7):944-9.
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  32. O'Rourke JA, Scharf JM, Yu D, Pauls DL. The genetics of Tourette syndrome: a review. J Psychosom Res. 2009 Dec; 67(6):533-45.
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  33. Shugart YY, Wang Y, Samuels JF, Grados MA, Greenberg BD, Knowles JA, McCracken JT, Rauch SL, Murphy DL, Rasmussen SA, Cullen B, Hoehn-Saric R, Pinto A, Fyer AJ, Piacentini J, Pauls DL, Bienvenu OJ, Riddle MA, Liang KY, Nestadt G. A family-based association study of the glutamate transporter gene SLC1A1 in obsessive-compulsive disorder in 378 families. Am J Med Genet B Neuropsychiatr Genet. 2009 Sep 5; 150B(6):886-92.
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  34. Mattila ML, Jussila K, Kuusikko S, Kielinen M, Linna SL, Ebeling H, Bloigu R, Joskitt L, Pauls D, Moilanen I. When does the Autism Spectrum Screening Questionnaire (ASSQ) predict autism spectrum disorders in primary school-aged children? Eur Child Adolesc Psychiatry. 2009 Aug; 18(8):499-509.
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  35. Bienvenu OJ, Wang Y, Shugart YY, Welch JM, Grados MA, Fyer AJ, Rauch SL, McCracken JT, Rasmussen SA, Murphy DL, Cullen B, Valle D, Hoehn-Saric R, Greenberg BD, Pinto A, Knowles JA, Piacentini J, Pauls DL, Liang KY, Willour VL, Riddle M, Samuels JF, Feng G, Nestadt G. Sapap3 and pathological grooming in humans: Results from the OCD collaborative genetics study. Am J Med Genet B Neuropsychiatr Genet. 2009 Jul 5; 150B(5):710-20.
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  36. Petryshen TL, Pauls DL. The genetics of reading disability. Curr Psychiatry Rep. 2009 Apr; 11(2):149-55.
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  37. Wang Y, Samuels JF, Chang YC, Grados MA, Greenberg BD, Knowles JA, McCracken JT, Rauch SL, Murphy DL, Rasmussen SA, Cullen B, Hoehn-Saric R, Pinto A, Fyer AJ, Piacentini J, Pauls DL, Bienvenu OJ, Riddle M, Shugart YY, Liang KY, Nestadt G. Gender differences in genetic linkage and association on 11p15 in obsessive-compulsive disorder families. Am J Med Genet B Neuropsychiatr Genet. 2009 Jan 5; 150B(1):33-40.
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  38. Nestadt G, Di CZ, Riddle MA, Grados MA, Greenberg BD, Fyer AJ, McCracken JT, Rauch SL, Murphy DL, Rasmussen SA, Cullen B, Pinto A, Knowles JA, Piacentini J, Pauls DL, Bienvenu OJ, Wang Y, Liang KY, Samuels JF, Roche KB. Obsessive-compulsive disorder: subclassification based on co-morbidity. Psychol Med. 2009 Sep; 39(9):1491-501.
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  39. Seixas AA, Hounie AG, Fossaluza V, Curi M, Alvarenga PG, De Mathis MA, De Mathis ME, Vallada H, Pauls D, de Bragança Pereira CA, Miguel EC. Anxiety disorders and rheumatic Fever: is there an association? CNS Spectr. 2008 Dec; 13(12):1039-46.
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  40. Platko JV, Wood FB, Pelser I, Meyer M, Gericke GS, O'Rourke J, Birns J, Purcell S, Pauls DL. Association of reading disability on chromosome 6p22 in the Afrikaner population. Am J Med Genet B Neuropsychiatr Genet. 2008 Oct 5; 147B(7):1278-87.
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  41. Hazen EP, Reichert EL, Piacentini JC, Miguel EC, do Rosario MC, Pauls D, Geller DA. Case series: Sensory intolerance as a primary symptom of pediatric OCD. Ann Clin Psychiatry. 2008 Oct-Dec; 20(4):199-203.
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  42. Liang KY, Wang Y, Shugart YY, Grados M, Fyer AJ, Rauch S, Murphy D, McCracken J, Rasmussen S, Cullen B, Hoehn-Saric R, Greenberg B, Pinto A, Knowles J, Piacentini J, Pauls D, Bienvenu O, Riddle M, Samuels J, Nestadt G. Evidence for potential relationship between SLC1A1 and a putative genetic linkage region on chromosome 14q to obsessive-compulsive disorder with compulsive hoarding. Am J Med Genet B Neuropsychiatr Genet. 2008 Sep 5; 147B(6):1000-2.
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  43. Geller DA, Wieland N, Carey K, Vivas F, Petty CR, Johnson J, Reichert E, Pauls D, Biederman J. Perinatal factors affecting expression of obsessive compulsive disorder in children and adolescents. J Child Adolesc Psychopharmacol. 2008 Aug; 18(4):373-9.
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  44. Hounie AG, Cappi C, Cordeiro Q, Sampaio AS, Moraes I, Rosário MC, Palácios SA, Goldberg AC, Vallada HP, Machado-Lima A, Nakano E, Kalil J, Pauls D, Pereira CA, Guilherme L, Miguel EC. TNF-alpha polymorphisms are associated with obsessive-compulsive disorder. Neurosci Lett. 2008 Sep 12; 442(2):86-90.
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  45. Robertson MM, Althoff RR, Hafez A, Pauls DL. Principal components analysis of a large cohort with Tourette syndrome. Br J Psychiatry. 2008 Jul; 193(1):31-6.
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  46. Stewart SE, Rosario MC, Baer L, Carter AS, Brown TA, Scharf JM, Illmann C, Leckman JF, Sukhodolsky D, Katsovich L, Rasmussen S, Goodman W, Delorme R, Leboyer M, Chabane N, Jenike MA, Geller DA, Pauls DL. Four-factor structure of obsessive-compulsive disorder symptoms in children, adolescents, and adults. J Am Acad Child Adolesc Psychiatry. 2008 Jul; 47(7):763-72.
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  47. Samuels JF, Bienvenu OJ, Pinto A, Murphy DL, Piacentini J, Rauch SL, Fyer AJ, Grados MA, Greenberg BD, Knowles JA, McCracken JT, Cullen B, Riddle MA, Rasmussen SA, Pauls DL, Liang KY, Hoehn-Saric R, Pulver AE, Nestadt G. Sex-specific clinical correlates of hoarding in obsessive-compulsive disorder. Behav Res Ther. 2008 Sep; 46(9):1040-6.
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  48. Pinto A, Greenberg BD, Grados MA, Bienvenu OJ, Samuels JF, Murphy DL, Hasler G, Stout RL, Rauch SL, Shugart YY, Pauls DL, Knowles JA, Fyer AJ, McCracken JT, Piacentini J, Wang Y, Willour VL, Cullen B, Liang KY, Hoehn-Saric R, Riddle MA, Rasmussen SA, Nestadt G. Further development of YBOCS dimensions in the OCD Collaborative Genetics study: symptoms vs. categories. Psychiatry Res. 2008 Jul 15; 160(1):83-93.
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  49. Pauls DL. The genetics of obsessive compulsive disorder: a review of the evidence. Am J Med Genet C Semin Med Genet. 2008 May 15; 148C(2):133-9.
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  50. Scharf JM, Moorjani P, Fagerness J, Platko JV, Illmann C, Galloway B, Jenike E, Stewart SE, Pauls DL. Lack of association between SLITRK1var321 and Tourette syndrome in a large family-based sample. Neurology. 2008 Apr 15; 70(16 Pt 2):1495-6.
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  51. de Kovel CG, Franke B, Hol FA, Lebrec JJ, Maassen B, Brunner H, Padberg GW, Platko J, Pauls D. Confirmation of dyslexia susceptibility loci on chromosomes 1p and 2p, but not 6p in a Dutch sib-pair collection. Am J Med Genet B Neuropsychiatr Genet. 2008 Apr 5; 147(3):294-300.
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  52. Kuusikko S, Pollock-Wurman R, Jussila K, Carter AS, Mattila ML, Ebeling H, Pauls DL, Moilanen I. Social anxiety in high-functioning children and adolescents with Autism and Asperger syndrome. J Autism Dev Disord. 2008 Oct; 38(9):1697-709.
    View in: PubMed
  53. Kim HG, Kishikawa S, Higgins AW, Seong IS, Donovan DJ, Shen Y, Lally E, Weiss LA, Najm J, Kutsche K, Descartes M, Holt L, Braddock S, Troxell R, Kaplan L, Volkmar F, Klin A, Tsatsanis K, Harris DJ, Noens I, Pauls DL, Daly MJ, MacDonald ME, Morton CC, Quade BJ, Gusella JF. Disruption of neurexin 1 associated with autism spectrum disorder. Am J Hum Genet. 2008 Jan; 82(1):199-207.
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  54. Cullen B, Samuels JF, Pinto A, Fyer AJ, McCracken JT, Rauch SL, Murphy DL, Greenberg BD, Knowles JA, Piacentini J, Bienvenu OJ, Grados MA, Riddle MA, Rasmussen SA, Pauls DL, Willour VL, Shugart YY, Liang KY, Hoehn-Saric R, Nestadt G. Demographic and clinical characteristics associated with treatment status in family members with obsessive-compulsive disorder. Depress Anxiety. 2008; 25(3):218-24.
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  55. Stewart SE, Fagerness JA, Platko J, Smoller JW, Scharf JM, Illmann C, Jenike E, Chabane N, Leboyer M, Delorme R, Jenike MA, Pauls DL. Association of the SLC1A1 glutamate transporter gene and obsessive-compulsive disorder. Am J Med Genet B Neuropsychiatr Genet. 2007 Dec 5; 144B(8):1027-33.
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  56. Lyons-Ruth K, Holmes BM, Sasvari-Szekely M, Ronai Z, Nemoda Z, Pauls D. Serotonin transporter polymorphism and borderline or antisocial traits among low-income young adults. Psychiatr Genet. 2007 Dec; 17(6):339-43.
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  57. Chacon P, Rosario-Campos MC, Pauls DL, Hounie AG, Curi M, Akkerman F, Shimabokuro FH, de Mathis MA, Lopes AC, Hasler G, Miguel EC. Obsessive-compulsive symptoms in sibling pairs concordant for obsessive-compulsive disorder. Am J Med Genet B Neuropsychiatr Genet. 2007 Jun 5; 144B(4):551-5.
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  58. Samuels J, Shugart YY, Grados MA, Willour VL, Bienvenu OJ, Greenberg BD, Knowles JA, McCracken JT, Rauch SL, Murphy DL, Wang Y, Pinto A, Fyer AJ, Piacentini J, Pauls DL, Cullen B, Rasmussen SA, Hoehn-Saric R, Valle D, Liang KY, Riddle MA, Nestadt G. Significant linkage to compulsive hoarding on chromosome 14 in families with obsessive-compulsive disorder: results from the OCD Collaborative Genetics Study. Am J Psychiatry. 2007 Mar; 164(3):493-9.
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  59. Stewart SE, Platko J, Fagerness J, Birns J, Jenike E, Smoller JW, Perlis R, Leboyer M, Delorme R, Chabane N, Rauch SL, Jenike MA, Pauls DL. A genetic family-based association study of OLIG2 in obsessive-compulsive disorder. Arch Gen Psychiatry. 2007 Feb; 64(2):209-14.
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  60. Geller D, Petty C, Vivas F, Johnson J, Pauls D, Biederman J. Further evidence for co-segregation between pediatric obsessive compulsive disorder and attention deficit hyperactivity disorder: a familial risk analysis. Biol Psychiatry. 2007 Jun 15; 61(12):1388-94.
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  61. Stewart SE, Rosario MC, Brown TA, Carter AS, Leckman JF, Sukhodolsky D, Katsovitch L, King R, Geller D, Pauls DL. Principal components analysis of obsessive-compulsive disorder symptoms in children and adolescents. Biol Psychiatry. 2007 Feb 1; 61(3):285-91.
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  62. Korpilahti P, Jansson-Verkasalo E, Mattila ML, Kuusikko S, Suominen K, Rytky S, Pauls DL, Moilanen I. Processing of affective speech prosody is impaired in Asperger syndrome. J Autism Dev Disord. 2007 Sep; 37(8):1539-49.
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  63. Stewart SE, Illmann C, Geller DA, Leckman JF, King R, Pauls DL. A controlled family study of attention-deficit/hyperactivity disorder and Tourette's disorder. J Am Acad Child Adolesc Psychiatry. 2006 Nov; 45(11):1354-62.
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  64. Hasler G, Pinto A, Greenberg BD, Samuels J, Fyer AJ, Pauls D, Knowles JA, McCracken JT, Piacentini J, Riddle MA, Rauch SL, Rasmussen SA, Willour VL, Grados MA, Cullen B, Bienvenu OJ, Shugart YY, Liang KY, Hoehn-Saric R, Wang Y, Ronquillo J, Nestadt G, Murphy DL. Familiality of factor analysis-derived YBOCS dimensions in OCD-affected sibling pairs from the OCD Collaborative Genetics Study. Biol Psychiatry. 2007 Mar 1; 61(5):617-25.
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  65. Geller D, Petty C, Vivas F, Johnson J, Pauls D, Biederman J. Examining the relationship between obsessive-compulsive disorder and attention-deficit/hyperactivity disorder in children and adolescents: a familial risk analysis. Biol Psychiatry. 2007 Feb 1; 61(3):316-21.
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  66. Eapen V, Pauls DL, Robertson MM. The role of clinical phenotypes in understanding the genetics of obsessive-compulsive disorder. J Psychosom Res. 2006 Sep; 61(3):359-64.
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  67. Samuels JF, Bienvenu OJ, Pinto A, Fyer AJ, McCracken JT, Rauch SL, Murphy DL, Grados MA, Greenberg BD, Knowles JA, Piacentini J, Cannistraro PA, Cullen B, Riddle MA, Rasmussen SA, Pauls DL, Willour VL, Shugart YY, Liang KY, Hoehn-Saric R, Nestadt G. Hoarding in obsessive-compulsive disorder: results from the OCD Collaborative Genetics Study. Behav Res Ther. 2007 Apr; 45(4):673-86.
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  68. Shugart YY, Samuels J, Willour VL, Grados MA, Greenberg BD, Knowles JA, McCracken JT, Rauch SL, Murphy DL, Wang Y, Pinto A, Fyer AJ, Piacentini J, Pauls DL, Cullen B, Page J, Rasmussen SA, Bienvenu OJ, Hoehn-Saric R, Valle D, Liang KY, Riddle MA, Nestadt G. Genomewide linkage scan for obsessive-compulsive disorder: evidence for susceptibility loci on chromosomes 3q, 7p, 1q, 15q, and 6q. Mol Psychiatry. 2006 Aug; 11(8):763-70.
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  69. Hounie AG, Pauls DL, do Rosario-Campos MC, Mercadante MT, Diniz JB, De Mathis MA, De Mathis ME, Chacon P, Shavitt RG, Curi M, Guilherme L, Miguel EC. Obsessive-compulsive spectrum disorders and rheumatic fever: a family study. Biol Psychiatry. 2007 Feb 1; 61(3):266-72.
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  70. Samuels JF, Riddle MA, Greenberg BD, Fyer AJ, McCracken JT, Rauch SL, Murphy DL, Grados MA, Pinto A, Knowles JA, Piacentini J, Cannistraro PA, Cullen B, Bienvenu OJ, Rasmussen SA, Pauls DL, Willour VL, Shugart YY, Liang KY, Hoehn-Saric R, Nestadt G. The OCD collaborative genetics study: methods and sample description. Am J Med Genet B Neuropsychiatr Genet. 2006 Apr 5; 141B(3):201-7.
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  71. Pauls DL. A genome-wide scan and fine mapping in Tourette syndrome families. Adv Neurol. 2006; 99:130-5.
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  72. Devlin B, Cook EH, Coon H, Dawson G, Grigorenko EL, McMahon W, Minshew N, Pauls D, Smith M, Spence MA, Rodier PM, Stodgell C, Schellenberg GD. Autism and the serotonin transporter: the long and short of it. Mol Psychiatry. 2005 Dec; 10(12):1110-6.
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  73. Abelson JF, Kwan KY, O'Roak BJ, Baek DY, Stillman AA, Morgan TM, Mathews CA, Pauls DL, Rasin MR, Gunel M, Davis NR, Ercan-Sencicek AG, Guez DH, Spertus JA, Leckman JF, Dure LS, Kurlan R, Singer HS, Gilbert DL, Farhi A, Louvi A, Lifton RP, Sestan N, State MW. Sequence variants in SLITRK1 are associated with Tourette's syndrome. Science. 2005 Oct 14; 310(5746):317-20.
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  74. van der Meulen EM, Bakker SC, Pauls DL, Oteman N, Kruitwagen CL, Pearson PL, Sinke RJ, Buitelaar JK. High sibling correlation on methylphenidate response but no association with DAT1-10R homozygosity in Dutch sibpairs with ADHD. J Child Psychol Psychiatry. 2005 Oct; 46(10):1074-80.
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  75. Chabane N, Delorme R, Millet B, Mouren MC, Leboyer M, Pauls D. Early-onset obsessive-compulsive disorder: a subgroup with a specific clinical and familial pattern? J Child Psychol Psychiatry. 2005 Aug; 46(8):881-7.
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  76. do Rosario-Campos MC, Leckman JF, Curi M, Quatrano S, Katsovitch L, Miguel EC, Pauls DL. A family study of early-onset obsessive-compulsive disorder. Am J Med Genet B Neuropsychiatr Genet. 2005 Jul 5; 136B(1):92-7.
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  77. Pauls DL. The genetics of attention-deficit/hyperactivity disorder. Biol Psychiatry. 2005 Jun 1; 57(11):1310-2.
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  78. Sukhodolsky DG, do Rosario-Campos MC, Scahill L, Katsovich L, Pauls DL, Peterson BS, King RA, Lombroso PJ, Findley DB, Leckman JF. Adaptive, emotional, and family functioning of children with obsessive-compulsive disorder and comorbid attention deficit hyperactivity disorder. Am J Psychiatry. 2005 Jun; 162(6):1125-32.
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  79. Klin A, Pauls D, Schultz R, Volkmar F. Three diagnostic approaches to Asperger syndrome: implications for research. J Autism Dev Disord. 2005 Apr; 35(2):221-34.
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  80. Stewart SE, Stack DE, Farrell C, Pauls DL, Jenike MA. Effectiveness of intensive residential treatment (IRT) for severe, refractory obsessive-compulsive disorder. J Psychiatr Res. 2005 Nov; 39(6):603-9.
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  81. Miguel EC, Leckman JF, Rauch S, do Rosario-Campos MC, Hounie AG, Mercadante MT, Chacon P, Pauls DL. Obsessive-compulsive disorder phenotypes: implications for genetic studies. Mol Psychiatry. 2005 Mar; 10(3):258-75.
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  82. Paschou P, Feng Y, Pakstis AJ, Speed WC, DeMille MM, Kidd JR, Jaghori B, Kurlan R, Pauls DL, Sandor P, Barr CL, Kidd KK. Indications of linkage and association of Gilles de la Tourette syndrome in two independent family samples: 17q25 is a putative susceptibility region. Am J Hum Genet. 2004 Oct; 75(4):545-60.
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  83. Kano Y, Ohta M, Nagai Y, Pauls DL, Leckman JF. Obsessive-compulsive symptoms in parents of Tourette syndrome probands and autism spectrum disorder probands. Psychiatry Clin Neurosci. 2004 Aug; 58(4):348-52.
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  84. Hounie AG, Pauls DL, Mercadante MT, Rosário-Campos MC, Shavitt RG, de Mathis MA, de Alvarenga PG, Cúri M, Miguel EC. Obsessive-compulsive spectrum disorders in rheumatic fever with and without Sydenham's chorea. J Clin Psychiatry. 2004 Jul; 65(7):994-9.
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  85. Stewart SE, Geller DA, Jenike M, Pauls D, Shaw D, Mullin B, Faraone SV. Long-term outcome of pediatric obsessive-compulsive disorder: a meta-analysis and qualitative review of the literature. Acta Psychiatr Scand. 2004 Jul; 110(1):4-13.
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  86. Devlin B, Bennett P, Dawson G, Figlewicz DA, Grigorenko EL, McMahon W, Minshew N, Pauls D, Smith M, Spence MA, Rodier PM, Stodgell C, Schellenberg GD. Alleles of a reelin CGG repeat do not convey liability to autism in a sample from the CPEA network. Am J Med Genet B Neuropsychiatr Genet. 2004 Apr 1; 126B(1):46-50.
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  87. Zohar AH, Shen G, Dycian A, Pauls D, Apter A, King R, Cohen D, Kron S. The Military Life Scale: a measure of perceived stress and support in the Israeli Defense Force. Isr J Psychiatry Relat Sci. 2004; 41(1):33-44.
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  88. Carter AS, Pollock RA, Suvak MK, Pauls DL. Anxiety and major depression comorbidity in a family study of obsessive-compulsive disorder. Depress Anxiety. 2004; 20(4):165-74.
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  89. Volkmar FR, Pauls D. Autism. Lancet. 2003 Oct 4; 362(9390):1133-41.
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  90. McMahon WM, Carter AS, Fredine N, Pauls DL. Children at familial risk for Tourette's disorder: Child and parent diagnoses. Am J Med Genet B Neuropsychiatr Genet. 2003 Aug 15; 121B(1):105-11.
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  91. Pauls DL. An update on the genetics of Gilles de la Tourette syndrome. J Psychosom Res. 2003 Jul; 55(1):7-12.
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  92. Schürhoff F, Szöke A, Méary A, Bellivier F, Rouillon F, Pauls D, Leboyer M. Familial aggregation of delusional proneness in schizophrenia and bipolar pedigrees. Am J Psychiatry. 2003 Jul; 160(7):1313-9.
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  93. Egeland JA, Shaw JA, Endicott J, Pauls DL, Allen CR, Hostetter AM, Sussex JN. Prospective study of prodromal features for bipolarity in well Amish children. J Am Acad Child Adolesc Psychiatry. 2003 Jul; 42(7):786-96.
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  94. State MW, Greally JM, Cuker A, Bowers PN, Henegariu O, Morgan TM, Gunel M, DiLuna M, King RA, Nelson C, Donovan A, Anderson GM, Leckman JF, Hawkins T, Pauls DL, Lifton RP, Ward DC. Epigenetic abnormalities associated with a chromosome 18(q21-q22) inversion and a Gilles de la Tourette syndrome phenotype. Proc Natl Acad Sci U S A. 2003 Apr 15; 100(8):4684-9.
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  95. Bakker SC, van der Meulen EM, Buitelaar JK, Sandkuijl LA, Pauls DL, Monsuur AJ, van 't Slot R, Minderaa RB, Gunning WB, Pearson PL, Sinke RJ. A whole-genome scan in 164 Dutch sib pairs with attention-deficit/hyperactivity disorder: suggestive evidence for linkage on chromosomes 7p and 15q. Am J Hum Genet. 2003 May; 72(5):1251-60.
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  96. Grigorenko EL, Wood FB, Golovyan L, Meyer M, Romano C, Pauls D. Continuing the search for dyslexia genes on 6p. Am J Med Genet B Neuropsychiatr Genet. 2003 Apr 1; 118B(1):89-98.
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  97. Leckman JF, Pauls DL, Zhang H, Rosario-Campos MC, Katsovich L, Kidd KK, Pakstis AJ, Alsobrook JP, Robertson MM, McMahon WM, Walkup JT, van de Wetering BJ, King RA, Cohen DJ. Obsessive-compulsive symptom dimensions in affected sibling pairs diagnosed with Gilles de la Tourette syndrome. Am J Med Genet B Neuropsychiatr Genet. 2003 Jan 1; 116B(1):60-8.
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  98. Grigorenko EL, Pauls DL. Analytical methods applied to psychiatric genetics. Methods Mol Med. 2003; 77:23-61.
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  99. Gelernter J, Page GP, Bonvicini K, Woods SW, Pauls DL, Kruger S. A chromosome 14 risk locus for simple phobia: results from a genomewide linkage scan. Mol Psychiatry. 2003 Jan; 8(1):71-82.
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  100. Kano Y, Leckman JF, Pauls DL. Clinical characteristics of Tourette syndrome probands and relatives' risks. J Am Acad Child Adolesc Psychiatry. 2002 Oct; 41(10):1148-9.
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  101. Devlin B, Bennett P, Cook EH, Dawson G, Gonen D, Grigorenko EL, McMahon W, Pauls D, Smith M, Spence MA, Schellenberg GD. No evidence for linkage of liability to autism to HOXA1 in a sample from the CPEA network. Am J Med Genet. 2002 Aug 8; 114(6):667-72.
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  102. Kaplan DE, Gayán J, Ahn J, Won TW, Pauls D, Olson RK, DeFries JC, Wood F, Pennington BF, Page GP, Smith SD, Gruen JR. Evidence for linkage and association with reading disability on 6p21.3-22. Am J Hum Genet. 2002 May; 70(5):1287-98.
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  103. Zhang H, Leckman JF, Pauls DL, Tsai CP, Kidd KK, Campos MR. Genomewide scan of hoarding in sib pairs in which both sibs have Gilles de la Tourette syndrome. Am J Hum Genet. 2002 Apr; 70(4):896-904.
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  104. Grigorenko EL, Klin A, Pauls DL, Senft R, Hooper C, Volkmar F. A descriptive study of hyperlexia in a clinically referred sample of children with developmental delays. J Autism Dev Disord. 2002 Feb; 32(1):3-12.
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  105. Alsobrook JP, Pauls DL. A factor analysis of tic symptoms in Gilles de la Tourette's syndrome. Am J Psychiatry. 2002 Feb; 159(2):291-6.
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  106. Alsobrook JP, Zohar AH, Leboyer M, Chabane N, Ebstein RP, Pauls DL. Association between the COMT locus and obsessive-compulsive disorder in females but not males. Am J Med Genet. 2002 Jan 8; 114(1):116-20.
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  107. Pato MT, Pato CN, Pauls DL. Recent findings in the genetics of OCD. J Clin Psychiatry. 2002; 63 Suppl 6:30-3.
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  108. Gelernter J, Bonvicini K, Page G, Woods SW, Goddard AW, Kruger S, Pauls DL, Goodson S. Linkage genome scan for loci predisposing to panic disorder or agoraphobia. Am J Med Genet. 2001 Aug 8; 105(6):548-57.
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  109. Zalsman G, Frisch A, King RA, Pauls DL, Grice DE, Gelernter J, Alsobrook J, Michaelovsky E, Apter A, Tyano S, Weizman A, Leckman JF. Case control and family-based studies of tryptophan hydroxylase gene A218C polymorphism and suicidality in adolescents. Am J Med Genet. 2001 Jul 8; 105(5):451-7.
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  110. Kano Y, Ohta M, Nagai Y, Pauls DL, Leckman JF. A family study of Tourette syndrome in Japan. Am J Med Genet. 2001 Jul 8; 105(5):414-21.
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  111. Pauls DL. The genetics of Tourette syndrome. Curr Psychiatry Rep. 2001 Apr; 3(2):152-7.
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  112. State MW, Pauls DL, Leckman JF. Tourette's syndrome and related disorders. Child Adolesc Psychiatr Clin N Am. 2001 Apr; 10(2):317-31, ix.
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  113. Hisama FM, Gruen JR, Choi J, Huseinovic M, Grigorenko EL, Pauls D, Mattson RH, Gelernter J, Wood FB, Goei VL. Human GABA(B) receptor 1 gene: eight novel sequence variants. Hum Mutat. 2001 Apr; 17(4):349-50.
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  114. Grigorenko EL, Wood FB, Meyer MS, Pauls JE, Hart LA, Pauls DL. Linkage studies suggest a possible locus for developmental dyslexia on chromosome 1p. Am J Med Genet. 2001 Jan 8; 105(1):120-9.
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  115. Leckman JF, Zhang H, Alsobrook JP, Pauls DL. Symptom dimensions in obsessive-compulsive disorder: toward quantitative phenotypes. Am J Med Genet. 2001 Jan 8; 105(1):28-30.
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  116. Pauls DL. Update on the genetics of Tourette syndrome. Adv Neurol. 2001; 85:281-93.
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  117. Alsobrook JP, Pauls DL. Genetics and violence. Child Adolesc Psychiatr Clin N Am. 2000 Oct; 9(4):765-76.
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  118. van den Heuvel OA, van de Wetering BJ, Veltman DJ, Pauls DL. Genetic studies of panic disorder: a review. J Clin Psychiatry. 2000 Oct; 61(10):756-66.
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  119. Egeland JA, Hostetter AM, Pauls DL, Sussex JN. Prodromal symptoms before onset of manic-depressive disorder suggested by first hospital admission histories. J Am Acad Child Adolesc Psychiatry. 2000 Oct; 39(10):1245-52.
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  120. Wolff M, Alsobrook JP, Pauls DL. Genetic aspects of obsessive-compulsive disorder. Psychiatr Clin North Am. 2000 Sep; 23(3):535-44.
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  121. State MW, Lombroso PJ, Pauls DL, Leckman JF. The genetics of childhood psychiatric disorders: a decade of progress. J Am Acad Child Adolesc Psychiatry. 2000 Aug; 39(8):946-62.
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  122. Grigorenko EL, Wood FB, Meyer MS, Pauls DL. Chromosome 6p influences on different dyslexia-related cognitive processes: further confirmation. Am J Hum Genet. 2000 Feb; 66(2):715-23.
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  123. Carter AS, O'Donnell DA, Schultz RT, Scahill L, Leckman JF, Pauls DL. Social and emotional adjustment in children affected with Gilles de la Tourette's syndrome: associations with ADHD and family functioning. Attention Deficit Hyperactivity Disorder. J Child Psychol Psychiatry. 2000 Feb; 41(2):215-23.
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  124. Alsobrook II JP, Leckman JF, Goodman WK, Rasmussen SA, Pauls DL. Segregation analysis of obsessive-compulsive disorder using symptom-based factor scores. Am J Med Genet. 1999 Dec 15; 88(6):669-75.
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  125. Robertson MM, Banerjee S, Kurlan R, Cohen DJ, Leckman JF, McMahon W, Pauls DL, Sandor P, van de Wetering BJ. The Tourette syndrome diagnostic confidence index: development and clinical associations. Neurology. 1999 Dec 10; 53(9):2108-12.
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  126. Barr CL, Wigg KG, Pakstis AJ, Kurlan R, Pauls D, Kidd KK, Tsui LC, Sandor P. Genome scan for linkage to Gilles de la Tourette syndrome. Am J Med Genet. 1999 Aug 20; 88(4):437-45.
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  127. Pauls DL, Alsobrook JP. The inheritance of obsessive-compulsive disorder. Child Adolesc Psychiatr Clin N Am. 1999 Jul; 8(3):481-96, viii.
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  128. Pauls D. Genetics of childhood disorders: IV. Linkage analysis. J Am Acad Child Adolesc Psychiatry. 1999 Jul; 38(7):932-4.
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  129. Jaume JC, Guo J, Pauls DL, Zakarija M, McKenzie JM, Egeland JA, Burek CL, Rose NR, Hoffman WH, Rapoport B, McLachlan SM. Evidence for genetic transmission of thyroid peroxidase autoantibody epitopic "fingerprints". J Clin Endocrinol Metab. 1999 Apr; 84(4):1424-31.
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  130. Volkmar FR, Klin A, Pauls D. Nosological and genetic aspects of Asperger syndrome. J Autism Dev Disord. 1998 Oct; 28(5):457-63.
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  131. Alsobrook JP, Pauls DL. Molecular approaches to child psychopathology. Hum Biol. 1998 Apr; 70(2):413-32.
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  132. Leboyer M, Bellivier F, Nosten-Bertrand M, Jouvent R, Pauls D, Mallet J. Psychiatric genetics: search for phenotypes. Trends Neurosci. 1998 Mar; 21(3):102-5.
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  133. Schultz RT, Carter AS, Gladstone M, Scahill L, Leckman JF, Peterson BS, Zhang H, Cohen DJ, Pauls D. Visual-motor integration functioning in children with Tourette syndrome. Neuropsychology. 1998 Jan; 12(1):134-45.
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  134. Leckman JF, Peterson BS, Pauls DL, Cohen DJ. Tic disorders. Psychiatr Clin North Am. 1997 Dec; 20(4):839-61.
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  135. Eapen V, Robertson MM, Alsobrook JP, Pauls DL. Obsessive compulsive symptoms in Gilles de la Tourette syndrome and obsessive compulsive disorder: differences by diagnosis and family history. Am J Med Genet. 1997 Jul 25; 74(4):432-8.
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  136. Leckman JF, Grice DE, Boardman J, Zhang H, Vitale A, Bondi C, Alsobrook J, Peterson BS, Cohen DJ, Rasmussen SA, Goodman WK, McDougle CJ, Pauls DL. Symptoms of obsessive-compulsive disorder. Am J Psychiatry. 1997 Jul; 154(7):911-7.
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  137. Cohen DJ, Leckman JF, Pauls D. Neuropsychiatric disorders of childhood: Tourette's syndrome as a model. Acta Paediatr Suppl. 1997 Jul; 422:106-11.
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  138. Alsobrook JP, Pauls DL. The genetics of Tourette syndrome. Neurol Clin. 1997 May; 15(2):381-93.
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  139. Evans DW, Leckman JF, Carter A, Reznick JS, Henshaw D, King RA, Pauls D. Ritual, habit, and perfectionism: the prevalence and development of compulsive-like behavior in normal young children. Child Dev. 1997 Feb; 68(1):58-68.
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  140. Zohar AH, Pauls DL, Ratzoni G, Apter A, Dycian A, Binder M, King R, Leckman JF, Kron S, Cohen DJ. Obsessive-compulsive disorder with and without tics in an epidemiological sample of adolescents. Am J Psychiatry. 1997 Feb; 154(2):274-6.
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  141. Leckman JF, Peterson BS, Anderson GM, Arnsten AF, Pauls DL, Cohen DJ. Pathogenesis of Tourette's syndrome. J Child Psychol Psychiatry. 1997 Jan; 38(1):119-42.
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  142. Grigorenko EL, Wood FB, Meyer MS, Hart LA, Speed WC, Shuster A, Pauls DL. Susceptibility loci for distinct components of developmental dyslexia on chromosomes 6 and 15. Am J Hum Genet. 1997 Jan; 60(1):27-39.
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  143. Grice DE, Leckman JF, Pauls DL, Kurlan R, Kidd KK, Pakstis AJ, Chang FM, Buxbaum JD, Cohen DJ, Gelernter J. Linkage disequilibrium between an allele at the dopamine D4 receptor locus and Tourette syndrome, by the transmission-disequilibrium test. Am J Hum Genet. 1996 Sep; 59(3):644-52.
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  144. Apter A, Fallon TJ, King RA, Ratzoni G, Zohar AH, Binder M, Weizman A, Leckman JF, Pauls DL, Kron S, Cohen DJ. Obsessive-compulsive characteristics: from symptoms to syndrome. J Am Acad Child Adolesc Psychiatry. 1996 Jul; 35(7):907-12.
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  145. Chappell P, Leckman J, Goodman W, Bissette G, Pauls D, Anderson G, Riddle M, Scahill L, McDougle C, Cohen D. Elevated cerebrospinal fluid corticotropin-releasing factor in Tourette's syndrome: comparison to obsessive compulsive disorder and normal controls. Biol Psychiatry. 1996 May 1; 39(9):776-83.
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  146. Ginns EI, Ott J, Egeland JA, Allen CR, Fann CS, Pauls DL, Weissenbachoff J, Carulli JP, Falls KM, Keith TP, Paul SM. A genome-wide search for chromosomal loci linked to bipolar affective disorder in the Old Order Amish. Nat Genet. 1996 Apr; 12(4):431-5.
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  147. Santangelo SL, Pauls DL, Lavori PW, Goldstein JM, Faraone SV, Tsuang MT. Assessing risk for the Tourette spectrum of disorders among first-degree relatives of probands with Tourette syndrome. Am J Med Genet. 1996 Feb 16; 67(1):107-16.
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  148. Gelernter J, Vandenbergh D, Kruger SD, Pauls DL, Kurlan R, Pakstis AJ, Kidd KK, Uhl G. The dopamine transporter protein gene (SLC6A3): primary linkage mapping and linkage studies in Tourette syndrome. Genomics. 1995 Dec 10; 30(3):459-63.
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  149. Carter AS, Grigorenko EL, Pauls DL. A Russian adaptation of the Child Behavior Checklist: psychometric properties and associations with child and maternal affective symptomatology and family function. J Abnorm Child Psychol. 1995 Dec; 23(6):661-84.
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  150. Pauls DL, Ott J, Paul SM, Allen CR, Fann CS, Carulli JP, Falls KM, Bouthillier CA, Gravius TC, Keith TP, et al. Linkage analyses of chromosome 18 markers do not identify a major susceptibility locus for bipolar affective disorder in the Old Order Amish. Am J Hum Genet. 1995 Sep; 57(3):636-43.
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  151. King RA, Zohar AH, Ratzoni G, Binder M, Kron S, Dycian A, Cohen DJ, Pauls DL, Apter A. An epidemiological study of trichotillomania in Israeli adolescents. J Am Acad Child Adolesc Psychiatry. 1995 Sep; 34(9):1212-5.
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  152. Pauls DL, Bailey JN, Carter AS, Allen CR, Egeland JA. Complex segregation analyses of old order Amish families ascertained through bipolar I individuals. Am J Med Genet. 1995 Aug 14; 60(4):290-7.
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  153. Gelernter J, Rao PA, Pauls DL, Hamblin MW, Sibley DR, Kidd KK. Assignment of the 5HT7 receptor gene (HTR7) to chromosome 10q and exclusion of genetic linkage with Tourette syndrome. Genomics. 1995 Mar 20; 26(2):207-9.
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  154. Leckman JF, Goodman WK, Anderson GM, Riddle MA, Chappell PB, McSwiggan-Hardin MT, McDougle CJ, Scahill LD, Ort SI, Pauls DL, et al. Cerebrospinal fluid biogenic amines in obsessive compulsive disorder, Tourette's syndrome, and healthy controls. Neuropsychopharmacology. 1995 Feb; 12(1):73-86.
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  155. Pauls DL, Alsobrook JP, Goodman W, Rasmussen S, Leckman JF. A family study of obsessive-compulsive disorder. Am J Psychiatry. 1995 Jan; 152(1):76-84.
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  156. Lombroso PJ, Scahill LD, Chappell PB, Pauls DL, Cohen DJ, Leckman JF. Tourette's syndrome: a multigenerational, neuropsychiatric disorder. Adv Neurol. 1995; 65:305-18.
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  157. Gerhard DS, LaBuda MC, Bland SD, Allen C, Egeland JA, Pauls DL. Initial report of a genome search for the affective disorder predisposition gene in the old order Amish pedigrees: chromosomes 1 and 11. Am J Med Genet. 1994 Dec 15; 54(4):398-404.
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  158. Leckman JF, Goodman WK, North WG, Chappell PB, Price LH, Pauls DL, Anderson GM, Riddle MA, McSwiggan-Hardin M, McDougle CJ, et al. Elevated cerebrospinal fluid levels of oxytocin in obsessive-compulsive disorder. Comparison with Tourette's syndrome and healthy controls. Arch Gen Psychiatry. 1994 Oct; 51(10):782-92.
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  159. Lombroso PJ, Pauls DL, Leckman JF. Genetic mechanisms in childhood psychiatric disorders. J Am Acad Child Adolesc Psychiatry. 1994 Sep; 33(7):921-38.
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  160. Santangelo SL, Pauls DL, Goldstein JM, Faraone SV, Tsuang MT, Leckman JF. Tourette's syndrome: what are the influences of gender and comorbid obsessive-compulsive disorder? J Am Acad Child Adolesc Psychiatry. 1994 Jul-Aug; 33(6):795-804.
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  161. Leckman JF, Walker DE, Goodman WK, Pauls DL, Cohen DJ. "Just right" perceptions associated with compulsive behavior in Tourette's syndrome. Am J Psychiatry. 1994 May; 151(5):675-80.
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  162. Gelernter J, Pauls DL, Leckman J, Kidd KK, Kurlan R. D2 dopamine receptor alleles do not influence severity of Tourette's syndrome. Results from four large kindreds. Arch Neurol. 1994 Apr; 51(4):397-400.
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  163. Carter AS, Pauls DL, Leckman JF, Cohen DJ. A prospective longitudinal study of Gilles de la Tourette's syndrome. J Am Acad Child Adolesc Psychiatry. 1994 Mar-Apr; 33(3):377-85.
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  164. Robertson MM, Verrill M, Mercer M, James B, Pauls DL. Tourette's syndrome in New Zealand. A postal survey. Br J Psychiatry. 1994 Feb; 164(2):263-6.
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  165. Pauls DL, Leckman JF, Cohen DJ. Evidence against a genetic relationship between Tourette's syndrome and anxiety, depression, panic and phobic disorders. Br J Psychiatry. 1994 Feb; 164(2):215-21.
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  166. Leckman JF, Goodman WK, North WG, Chappell PB, Price LH, Pauls DL, Anderson GM, Riddle MA, McDougle CJ, Barr LC, et al. The role of central oxytocin in obsessive compulsive disorder and related normal behavior. Psychoneuroendocrinology. 1994; 19(8):723-49.
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  167. LaBuda MC, Fletcher NA, Korczyn AD, Inzelberg R, Harding AE, Pauls DL. Genomic imprinting and anticipation in idiopathic torsion dystonia. Neurology. 1993 Oct; 43(10):2040-3.
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  168. Pauls DL, Zakarija M, McKenzie JM, Egeland JA. Complex segregation analysis of antibodies to thyroid peroxidase in Old Order Amish families. Am J Med Genet. 1993 Sep 1; 47(3):375-9.
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  169. Apter A, Pauls DL, Bleich A, Zohar AH, Kron S, Ratzoni G, Dycian A, Kotler M, Weizman A, Gadot N, et al. An epidemiologic study of Gilles de la Tourette's syndrome in Israel. Arch Gen Psychiatry. 1993 Sep; 50(9):734-8.
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  170. Pauls DL, Leckman JF, Cohen DJ. Familial relationship between Gilles de la Tourette's syndrome, attention deficit disorder, learning disabilities, speech disorders, and stuttering. J Am Acad Child Adolesc Psychiatry. 1993 Sep; 32(5):1044-50.
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  171. Eapen V, Pauls DL, Robertson MM. Evidence for autosomal dominant transmission in Tourette's syndrome. United Kingdom cohort study. Br J Psychiatry. 1993 May; 162:593-6.
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  172. LaBuda MC, Gottesman II, Pauls DL. Usefulness of twin studies for exploring the etiology of childhood and adolescent psychiatric disorders. Am J Med Genet. 1993 May 1; 48(1):47-59.
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  173. Gelernter J, Kennedy JL, Grandy DK, Zhou QY, Civelli O, Pauls DL, Pakstis A, Kurlan R, Sunahara RK, Niznik HB, et al. Exclusion of close linkage of Tourette's syndrome to D1 dopamine receptor. Am J Psychiatry. 1993 Mar; 150(3):449-53.
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  174. Pauls DL. The genetics of obsessive compulsive disorder and Gilles de la Tourette's syndrome. Psychiatr Clin North Am. 1992 Dec; 15(4):759-66.
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  175. Zohar AH, Ratzoni G, Pauls DL, Apter A, Bleich A, Kron S, Rappaport M, Weizman A, Cohen DJ. An epidemiological study of obsessive-compulsive disorder and related disorders in Israeli adolescents. J Am Acad Child Adolesc Psychiatry. 1992 Nov; 31(6):1057-61.
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  176. Porges SW, Matthews KA, Pauls DL. The biobehavioral interface in behavioral pediatrics. Pediatrics. 1992 Nov; 90(5 Pt 2):789-97.
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  177. Ginns EI, Egeland JA, Allen CR, Pauls DL, Falls K, Keith TP, Paul SM. Update on the search for DNA markers linked to manic-depressive illness in the Old Order Amish. J Psychiatr Res. 1992 Oct; 26(4):305-8.
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  178. Pauls DL, Morton LA, Egeland JA. Risks of affective illness among first-degree relatives of bipolar I old-order Amish probands. Arch Gen Psychiatry. 1992 Sep; 49(9):703-8.
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  179. Leckman JF, Pauls DL, Peterson BS, Riddle MA, Anderson GM, Cohen DJ. Pathogenesis of Tourette syndrome. Clues from the clinical phenotype and natural history. Adv Neurol. 1992; 58:15-24.
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  180. Apter A, Pauls DL, Bleich A, Zohar AH, Kron S, Ratzoni G, Dycian A, Kotler M, Weizman A, Cohen DJ. A population-based epidemiological study of Tourette syndrome among adolescents in Israel. Adv Neurol. 1992; 58:61-5.
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  181. Pauls DL. Issues in genetic linkage studies of Tourette syndrome. Phenotypic spectrum and genetic model parameters. Adv Neurol. 1992; 58:151-7.
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  182. Pauls DL, Gerhard DS, Lacy LG, Hostetter AM, Allen CR, Bland SD, LaBuda MC, Egeland JA. Linkage of bipolar affective disorders to markers on chromosome 11p is excluded in a second lateral extension of Amish pedigree 110. Genomics. 1991 Nov; 11(3):730-6.
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  183. Pennington BF, Gilger JW, Pauls D, Smith SA, Smith SD, DeFries JC. Evidence for major gene transmission of developmental dyslexia. JAMA. 1991 Sep 18; 266(11):1527-34.
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  184. Pakstis AJ, Heutink P, Pauls DL, Kurlan R, van de Wetering BJ, Leckman JF, Sandkuyl LA, Kidd JR, Breedveld GJ, Castiglione CM, et al. Progress in the search for genetic linkage with Tourette syndrome: an exclusion map covering more than 50% of the autosomal genome. Am J Hum Genet. 1991 Feb; 48(2):281-94.
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  185. Heutink P, Sandkuyl LA, van de Wetering BJ, Oostra BA, Weber J, Wilkie P, Devor EJ, Pakstis AJ, Pauls D, Kidd KK. Linkage and Tourette syndrome. Lancet. 1991 Jan 12; 337(8733):122-3.
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  186. Pauls DL, Raymond CL, Stevenson JM, Leckman JF. A family study of Gilles de la Tourette syndrome. Am J Hum Genet. 1991 Jan; 48(1):154-63.
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  187. Pauls DL. Genetic factors in the expression of attention-deficit hyperactivity disorder. J Child Adolesc Psychopharmacol. 1991; 1(5):353-60.
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  188. Rounsaville BJ, Kosten TR, Weissman MM, Prusoff B, Pauls D, Anton SF, Merikangas K. Psychiatric disorders in relatives of probands with opiate addiction. Arch Gen Psychiatry. 1991 Jan; 48(1):33-42.
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  189. Gelernter J, Pakstis AJ, Pauls DL, Kurlan R, Gancher ST, Civelli O, Grandy D, Kidd KK. Gilles de la Tourette syndrome is not linked to D2-dopamine receptor. Arch Gen Psychiatry. 1990 Nov; 47(11):1073-7.
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  190. Goodman WK, McDougle CJ, Price LH, Riddle MA, Pauls DL, Leckman JF. Beyond the serotonin hypothesis: a role for dopamine in some forms of obsessive compulsive disorder? J Clin Psychiatry. 1990 Aug; 51 Suppl:36-43; discussion 55-8.
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  191. Pauls DL, Korczyn AD. Complex segregation analysis of dystonia pedigrees suggests autosomal dominant inheritance. Neurology. 1990 Jul; 40(7):1107-10.
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  192. Lenane MC, Swedo SE, Leonard H, Pauls DL, Sceery W, Rapoport JL. Psychiatric disorders in first degree relatives of children and adolescents with obsessive compulsive disorder. J Am Acad Child Adolesc Psychiatry. 1990 May; 29(3):407-12.
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  193. Pauls DL, Pakstis AJ, Kurlan R, Kidd KK, Leckman JF, Cohen DJ, Kidd JR, Como P, Sparkes R. Segregation and linkage analyses of Tourette's syndrome and related disorders. J Am Acad Child Adolesc Psychiatry. 1990 Mar; 29(2):195-203.
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  194. Leckman JF, Pauls DL. Genetics and child psychiatry. J Am Acad Child Adolesc Psychiatry. 1990 Mar; 29(2):174-6.
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  195. Leckman JF, Dolnansky ES, Hardin MT, Clubb M, Walkup JT, Stevenson J, Pauls DL. Perinatal factors in the expression of Tourette's syndrome: an exploratory study. J Am Acad Child Adolesc Psychiatry. 1990 Mar; 29(2):220-6.
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  196. Kelsoe JR, Ginns EI, Egeland JA, Gerhard DS, Goldstein AM, Bale SJ, Pauls DL, Long RT, Kidd KK, Conte G, et al. Re-evaluation of the linkage relationship between chromosome 11p loci and the gene for bipolar affective disorder in the Old Order Amish. Nature. 1989 Nov 16; 342(6247):238-43.
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  197. Kurlan R, Kidd KK, Pauls D. Linkage analysis approach to hereditary movement disorders. J Neurogenet. 1989 Jul; 5(3):161-71.
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  198. Kramer PL, Pauls DL, Price RA, Kidd KK. Estimation of segregation and linkage parameters in simulated data. I. Segregation analyses with different ascertainment schemes. Am J Hum Genet. 1989 Jul; 45(1):83-94.
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  199. Price RA, Kramer PL, Pauls DL, Kidd KK. Estimation of segregation and linkage parameters in simulated data. II. Simultaneous estimation with one linked marker. Am J Hum Genet. 1989 Jul; 45(1):95-105.
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  200. Egeland JA, Gerhard DS, Pauls DL. Description of Amish Study data set. Genet Epidemiol. 1989; 6(1):195-9.
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  201. Pauls DL, Cohen DJ, Kidd KK, Leckman JF. Tourette syndrome and neuropsychiatric disorders: is there a genetic relationship? Am J Hum Genet. 1988 Aug; 43(2):206-17.
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  202. Price RA, Pauls DL, Kruger SD, Caine ED. Family data support a dominant major gene for Tourette syndrome. Psychiatry Res. 1988 Jun; 24(3):251-61.
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  203. Watson MS, Breg WR, Pauls D, Brown WT, Carroll AJ, Howard-Peebles PN, Meryash D, Shapiro LR. Aneuploidy and the fragile X syndrome. Am J Med Genet. 1988 May-Jun; 30(1-2):115-21.
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  204. Leckman JF, Weissman MM, Pauls DL, Kidd KK. Family-genetic studies and identification of valid diagnostic categories in adult and child psychiatry. Br J Psychiatry. 1987 Jul; 151:39-44.
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  205. Kurlan R, Behr J, Medved L, Shoulson I, Pauls D, Kidd KK. Severity of Tourette's syndrome in one large kindred. Implication for determination of disease prevalence rate. Arch Neurol. 1987 Mar; 44(3):268-9.
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  206. Egeland JA, Gerhard DS, Pauls DL, Sussex JN, Kidd KK, Allen CR, Hostetter AM, Housman DE. Bipolar affective disorders linked to DNA markers on chromosome 11. Nature. 1987 Feb 26-Mar 4; 325(6107):783-7.
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  207. Leckman JF, Price RA, Walkup JT, Ort S, Pauls DL, Cohen DJ. Nongenetic factors in Gilles de la Tourette's syndrome. Arch Gen Psychiatry. 1987 Jan; 44(1):100.
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  208. Gerhard DS, Egeland JA, Pauls DL, Housman DE. Search for a gene that predisposes individuals to BPI disorder. J Psychiatr Res. 1987; 21(4):569-75.
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  209. Pauls DL, Hurst CR, Kruger SD, Leckman JF, Kidd KK, Cohen DJ. Gilles de la Tourette's syndrome and attention deficit disorder with hyperactivity. Evidence against a genetic relationship. Arch Gen Psychiatry. 1986 Dec; 43(12):1177-9.
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  210. Pauls DL, Towbin KE, Leckman JF, Zahner GE, Cohen DJ. Gilles de la Tourette's syndrome and obsessive-compulsive disorder. Evidence supporting a genetic relationship. Arch Gen Psychiatry. 1986 Dec; 43(12):1180-2.
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  211. Pauls DL, Leckman JF. The inheritance of Gilles de la Tourette's syndrome and associated behaviors. Evidence for autosomal dominant transmission. N Engl J Med. 1986 Oct 16; 315(16):993-7.
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  212. Kurlan R, Behr J, Medved L, Shoulson I, Pauls D, Kidd JR, Kidd KK. Familial Tourette's syndrome: report of a large pedigree and potential for linkage analysis. Neurology. 1986 Jun; 36(6):772-6.
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  213. Weissman MM, Merikangas KR, Wickramaratne P, Kidd KK, Prusoff BA, Leckman JF, Pauls DL. Understanding the clinical heterogeneity of major depression using family data. Arch Gen Psychiatry. 1986 May; 43(5):430-4.
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  214. Price RA, Leckman JF, Pauls DL, Cohen DJ, Kidd KK. Gilles de la Tourette's syndrome: tics and central nervous system stimulants in twins and nontwins. Neurology. 1986 Feb; 36(2):232-7.
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  215. Pauls DL, Leckman JF, Towbin KE, Zahner GE, Cohen DJ. A possible genetic relationship exists between Tourette's syndrome and obsessive-compulsive disorder. Psychopharmacol Bull. 1986; 22(3):730-3.
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  216. Price RA, Kidd KK, Cohen DJ, Pauls DL, Leckman JF. A twin study of Tourette syndrome. Arch Gen Psychiatry. 1985 Aug; 42(8):815-20.
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  217. Merikangas KR, Weissman MM, Prusoff BA, Pauls DL, Leckman JF. Depressives with secondary alcoholism: psychiatric disorders in offspring. J Stud Alcohol. 1985 May; 46(3):199-204.
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  218. Merikangas KR, Leckman JF, Prusoff BA, Pauls DL, Weissman MM. Familial transmission of depression and alcoholism. Arch Gen Psychiatry. 1985 Apr; 42(4):367-72.
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  219. Merikangas KR, Weissman MM, Pauls DL. Genetic factors in the sex ratio of major depression. Psychol Med. 1985 Feb; 15(1):63-9.
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  220. Leckman JF, Weissman MM, Merikangas KR, Pauls DL, Prusoff BA, Kidd KK. Major depression and panic disorder: a family study perspective. Psychopharmacol Bull. 1985; 21(3):543-5.
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  221. Price RA, Kidd KK, Pauls DL, Gershon ES, Prusoff BA, Weissman MM, Goldin LR. Multiple threshold models for the affective disorders: the Yale-NIMH collaborative family study. J Psychiatr Res. 1985; 19(4):533-46.
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  222. Leckman JF, Weissman MM, Prusoff BA, Caruso KA, Merikangas KR, Pauls DL, Kidd KK. Subtypes of depression. Family study perspective. Arch Gen Psychiatry. 1984 Sep; 41(9):833-8.
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  223. Kidd KK, Egeland JA, Molthan L, Pauls DL, Kruger SD, Messner KH. Amish study, IV: Genetic linkage study of pedigrees of bipolar probands. Am J Psychiatry. 1984 Sep; 141(9):1042-8.
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  224. Leckman JF, Caruso KA, Prusoff BA, Weissman MM, Merikangas KR, Pauls DL. Appetite disturbance and excessive guilt in major depression. Use of family study data to define depressive subtypes. Arch Gen Psychiatry. 1984 Sep; 41(9):839-44.
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  225. Campbell J, Crowe RR, Goeken N, Pfohl B, Pauls D, Palmer D. Affective disorder not linked to HLA in a large bipolar kindred. J Affect Disord. 1984 Aug; 7(1):45-51.
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  226. Leckman JF, Weissman MM, Merikangas KR, Pauls DL, Prusoff BA. Methodologic differences in major depression and panic disorder studies. Arch Gen Psychiatry. 1984 Jul; 41(7):722-3.
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  227. Pauls DL, Kruger SD, Leckman JF, Cohen DJ, Kidd KK. The risk of Tourette's syndrome and chronic multiple tics among relatives of Tourette's syndrome patients obtained by direct interview. J Am Acad Child Psychiatry. 1984 Mar; 23(2):134-7.
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  228. Weissman MM, Gershon ES, Kidd KK, Prusoff BA, Leckman JF, Dibble E, Hamovit J, Thompson WD, Pauls DL, Guroff JJ. Psychiatric disorders in the relatives of probands with affective disorders. The Yale University--National Institute of Mental Health Collaborative Study. Arch Gen Psychiatry. 1984 Jan; 41(1):13-21.
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  229. Goldin LR, Cox NJ, Pauls DL, Gershon ES, Kidd KK. The detection of major loci by segregation and linkage analysis: a simulation study. Genet Epidemiol. 1984; 1(3):285-96.
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  230. Crowe RR, Noyes R, Pauls DL, Slymen D. A family study of panic disorder. Arch Gen Psychiatry. 1983 Oct; 40(10):1065-9.
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  231. Leckman JF, Weissman MM, Merikangas KR, Pauls DL, Prusoff BA. Panic disorder and major depression. Increased risk of depression, alcoholism, panic, and phobic disorders in families of depressed probands with panic disorder. Arch Gen Psychiatry. 1983 Oct; 40(10):1055-60.
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  232. Leckman JF, Merikangas KR, Pauls DL, Prusoff BA, Weissman MM. Anxiety disorders and depression: contradictions between family study data and DSM-III conventions. Am J Psychiatry. 1983 Jul; 140(7):880-2.
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  233. Pauls DL, Kidd KK. Genetic strategies for the analysis of childhood behavioral traits. Schizophr Bull. 1982; 8(2):253-66.
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  234. Kidd KK, Pauls DL. Genetic hypotheses for Tourette syndrome. Adv Neurol. 1982; 35:243-9.
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  235. Pauls DL, Cohen DJ, Heimbuch R, Detlor J, Kidd KK. Familial pattern and transmission of Gilles de la Tourette syndrome and multiple tics. Arch Gen Psychiatry. 1981 Oct; 38(10):1091-3.
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  236. Pauls DL, Bucher KD, Crowe RR, Noyes R. A genetic study of panic disorder pedigrees. Am J Hum Genet. 1980 Sep; 32(5):639-44.
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  237. Venkatesh A, Pauls DL, Crowe R, Noyes R, Van Valkenburg C, Martins JB, Kerber RE. Mitral valve prolapse in anxiety neurosis (panic disorder). Am Heart J. 1980 Sep; 100(3):302-5.
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  238. Crowe RC, Pauls DL, Slymen DJ, Noyes R. A family study of anxiety neurosis. Morbidity risk in families of patients with and without mitral valve prolapse. Arch Gen Psychiatry. 1980 Jan; 37(1):77-9.
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  239. Pauls DL, Noyes R, Crowe RR. The familial prevalence in second-degree relatives of patients with anxiety neurosis (panic disorder). J Affect Disord. 1979 Dec; 1(4):279-85.
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  240. Pauls DL, Crowe RR, Noyes R. Distribution of ancestral secondary cases in anxiety neurosis (panic disorder). J Affect Disord. 1979 Dec; 1(4):387-90.
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  241. Pauls DL. Sex effect on the risk of mental retardation. Behav Genet. 1979 Jul; 9(4):289-95.
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  242. Crowe RR, Pauls DL, Venkatesh A, Van Valkenburg C, Noyes R, Martins JB, Kerber RE. Exercise and anxiety neurosis: comparison of patients with and without mitral valve prolapse. Arch Gen Psychiatry. 1979 Jun; 36(6):652-3.
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