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Last Name
Institution

Ronald M. Hansen, PH.D.

TitleInstructor in Ophthalmology
InstitutionChildren's Hospital Boston
DepartmentOphthalmology
AddressChildrens Hospital
Ophthalmology
300 Longwood Ave
Boston MA 02115
Phone617/355-7991
Fax617/730-0392

 Bibliographic 
 selected publications
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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  1. Zhang N, Favazza TL, Baglieri AM, Benador IY, Noonan ER, Fulton AB, Hansen RM, Iuvone PM, Akula JD. The rat with oxygen-induced retinopathy is myopic with low retinal dopamine. Invest Ophthalmol Vis Sci. 2013 Dec; 54(13):8275-84.
    View in: PubMed
  2. Raghuram A, Hansen RM, Moskowitz A, Fulton AB. Photoreceptor and postreceptor responses in congenital stationary night blindness. Invest Ophthalmol Vis Sci. 2013; 54(7):4648-58.
    View in: PubMed
  3. Griffith RM, Li H, Zhang N, Favazza TL, Fulton AB, Hansen RM, Akula JD. Next-generation sequencing analysis of gene regulation in the rat model of retinopathy of prematurity. Doc Ophthalmol. 2013 Aug; 127(1):13-31.
    View in: PubMed
  4. Favazza TL, Tanimoto N, Munro RJ, Beck SC, Garcia Garrido M, Seide C, Sothilingam V, Hansen RM, Fulton AB, Seeliger MW, Akula JD. Alterations of the tunica vasculosa lentis in the rat model of retinopathy of prematurity. Doc Ophthalmol. 2013 Aug; 127(1):3-11.
    View in: PubMed
  5. Moskowitz A, Hansen RM, Eklund SE, Fulton AB. Electroretinographic (ERG) responses in pediatric patients using vigabatrin. Doc Ophthalmol. 2012 Jun; 124(3):197-209.
    View in: PubMed
  6. Rubin LP, Chan GM, Barrett-Reis BM, Fulton AB, Hansen RM, Ashmeade TL, Oliver JS, Mackey AD, Dimmit RA, Hartmann EE, Adamkin DH. Effect of carotenoid supplementation on plasma carotenoids, inflammation and visual development in preterm infants. J Perinatol. 2012 Jun; 32(6):418-24.
    View in: PubMed
  7. Harris ME, Moskowitz A, Fulton AB, Hansen RM. Long-term effects of retinopathy of prematurity (ROP) on rod and rod-driven function. Doc Ophthalmol. 2011 Feb; 122(1):19-27.
    View in: PubMed
  8. Garry D, Hansen RM, Moskowitz A, Elias ER, Irons M, Fulton AB. Cone ERG responses in patients with Smith-Lemli-Opitz Syndrome (SLOS). Doc Ophthalmol. 2010 Oct; 121(2):85-91.
    View in: PubMed
  9. Akula JD, Hansen RM, Tzekov R, Favazza TL, Vyhovsky TC, Benador IY, Mocko JA, McGee D, Kubota R, Fulton AB. Visual cycle modulation in neurovascular retinopathy. Exp Eye Res. 2010 Aug; 91(2):153-61.
    View in: PubMed
  10. Hansen RM, Harris ME, Moskowitz A, Fulton AB. Deactivation of the rod response in retinopathy of prematurity. Doc Ophthalmol. 2010 Aug; 121(1):29-35.
    View in: PubMed
  11. Akula JD, Favazza TL, Mocko JA, Benador IY, Asturias AL, Kleinman MS, Hansen RM, Fulton AB. The anatomy of the rat eye with oxygen-induced retinopathy. Doc Ophthalmol. 2010 Feb; 120(1):41-50.
    View in: PubMed
  12. Fulton AB, Hansen RM, Moskowitz A, Akula JD. The neurovascular retina in retinopathy of prematurity. Prog Retin Eye Res. 2009 Nov; 28(6):452-82.
    View in: PubMed
  13. Fulton AB, Hansen RM, Moskowitz A. Development of rod function in term born and former preterm subjects. Optom Vis Sci. 2009 Jun; 86(6):E653-8.
    View in: PubMed
  14. Agrawal S, Mayer DL, Hansen RM, Fulton AB. Visual fields in young children treated with vigabatrin. Optom Vis Sci. 2009 Jun; 86(6):767-73.
    View in: PubMed
  15. Akula JD, Mocko JA, Benador IY, Hansen RM, Favazza TL, Vyhovsky TC, Fulton AB. The neurovascular relation in oxygen-induced retinopathy. Mol Vis. 2008; 14:2499-508.
    View in: PubMed
  16. Moskowitz A, Hansen RM, Akula JD, Eklund SE, Fulton AB. Rod and rod-driven function in achromatopsia and blue cone monochromatism. Invest Ophthalmol Vis Sci. 2009 Feb; 50(2):950-8.
    View in: PubMed
  17. Hansen RM, Moskowitz A, Fulton AB. Multifocal ERG responses in infants. Invest Ophthalmol Vis Sci. 2009 Jan; 50(1):470-5.
    View in: PubMed
  18. Fulton AB, Akula JD, Mocko JA, Hansen RM, Benador IY, Beck SC, Fahl E, Seeliger MW, Moskowitz A, Harris ME. Retinal degenerative and hypoxic ischemic disease. Doc Ophthalmol. 2009 Feb; 118(1):55-61.
    View in: PubMed
  19. Fulton AB, Hansen RM, Moskowitz A. The cone electroretinogram in retinopathy of prematurity. Invest Ophthalmol Vis Sci. 2008 Feb; 49(2):814-9.
    View in: PubMed
  20. Akula JD, Mocko JA, Moskowitz A, Hansen RM, Fulton AB. The oscillatory potentials of the dark-adapted electroretinogram in retinopathy of prematurity. Invest Ophthalmol Vis Sci. 2007 Dec; 48(12):5788-97.
    View in: PubMed
  21. Lu M, Hansen RM, Cunningham MJ, Eklund SE, Fulton AB. Effects of desferoxamine on retinal and visual function. Arch Ophthalmol. 2007 Nov; 125(11):1581-2.
    View in: PubMed
  22. Barnaby AM, Hansen RM, Moskowitz A, Fulton AB. Development of scotopic visual thresholds in retinopathy of prematurity. Invest Ophthalmol Vis Sci. 2007 Oct; 48(10):4854-60.
    View in: PubMed
  23. Akula JD, Hansen RM, Martinez-Perez ME, Fulton AB. Rod photoreceptor function predicts blood vessel abnormality in retinopathy of prematurity. Invest Ophthalmol Vis Sci. 2007 Sep; 48(9):4351-9.
    View in: PubMed
  24. Hansen RM, Eklund SE, Benador IY, Mocko JA, Akula JD, Liu Y, Martinez-Perez ME, Fulton AB. Retinal degeneration in children: dark adapted visual threshold and arteriolar diameter. Vision Res. 2008 Feb; 48(3):325-31.
    View in: PubMed
  25. Liu K, Akula JD, Hansen RM, Moskowitz A, Kleinman MS, Fulton AB. Development of the electroretinographic oscillatory potentials in normal and ROP rats. Invest Ophthalmol Vis Sci. 2006 Dec; 47(12):5447-52.
    View in: PubMed
  26. Liu K, Akula JD, Falk C, Hansen RM, Fulton AB. The retinal vasculature and function of the neural retina in a rat model of retinopathy of prematurity. Invest Ophthalmol Vis Sci. 2006 Jun; 47(6):2639-47.
    View in: PubMed
  27. Lutty GA, Chan-Ling T, Phelps DL, Adamis AP, Berns KI, Chan CK, Cole CH, D'Amore PA, Das A, Deng WT, Dobson V, Flynn JT, Friedlander M, Fulton A, Good WV, Grant MB, Hansen R, Hauswirth WW, Hardy RJ, Hinton DR, Hughes S, McLeod DS, Palmer EA, Patz A, Penn JS, Raisler BJ, Repka MX, Saint-Geniez M, Shaw LC, Shima DT, Smith BT, Smith LE, Tahija SG, Tasman W, Trese MT. Proceedings of the Third International Symposium on Retinopathy of Prematurity: an update on ROP from the lab to the nursery (November 2003, Anaheim, California). Mol Vis. 2006; 12:532-80.
    View in: PubMed
  28. Fulton AB, Hansen RM, Moskowitz A, Barnaby AM. Multifocal ERG in subjects with a history of retinopathy of prematurity. Doc Ophthalmol. 2005 Jul; 111(1):7-13.
    View in: PubMed
  29. Lim M, Soul JS, Hansen RM, Mayer DL, Moskowitz A, Fulton AB. Development of visual acuity in children with cerebral visual impairment. Arch Ophthalmol. 2005 Sep; 123(9):1215-20.
    View in: PubMed
  30. Hansen RM, Fulton AB. Development of the cone ERG in infants. Invest Ophthalmol Vis Sci. 2005 Sep; 46(9):3458-62.
    View in: PubMed
  31. Tsina EK, Marsden DL, Hansen RM, Fulton AB. Maculopathy and retinal degeneration in cobalamin C methylmalonic aciduria and homocystinuria. Arch Ophthalmol. 2005 Aug; 123(8):1143-6.
    View in: PubMed
  32. Moskowitz A, Hansen R, Fulton A. Early ametropia and rod photoreceptor function in retinopathy of prematurity. Optom Vis Sci. 2005 Apr; 82(4):307-17.
    View in: PubMed
  33. Moskowitz A, Hansen RM, Fulton AB. ERG oscillatory potentials in infants. Doc Ophthalmol. 2005 Mar-May; 110(2-3):265-70.
    View in: PubMed
  34. Hansen RM, Fulton AB. Recovery of the rod photoresponse in infants. Invest Ophthalmol Vis Sci. 2005 Feb; 46(2):764-8.
    View in: PubMed
  35. Bradshaw K, Hansen R, Fulton A. Comparison of ERGs recorded with skin and corneal-contact electrodes in normal children and adults. Doc Ophthalmol. 2004 Jul; 109(1):43-55.
    View in: PubMed
  36. Elias ER, Hansen RM, Irons M, Quinn NB, Fulton AB. Rod photoreceptor responses in children with Smith-Lemli-Opitz syndrome. Arch Ophthalmol. 2003 Dec; 121(12):1738-43.
    View in: PubMed
  37. Fulton AB, Hansen RM. Recovery of the rod photoresponse in infant rats. Vision Res. 2003 Dec; 43(28):3081-5.
    View in: PubMed
  38. Fulton AB, Hansen RM, Westall CA. Development of ERG responses: the ISCEV rod, maximal and cone responses in normal subjects. Doc Ophthalmol. 2003 Nov; 107(3):235-41.
    View in: PubMed
  39. Chaudhary V, Hansen R, Lindgren H, Fulton A. Effects of telazol and nembutal on retinal responses. Doc Ophthalmol. 2003 Jul; 107(1):45-51.
    View in: PubMed
  40. Cox GF, Hansen RM, Quinn N, Fulton AB. Retinal function in carriers of Bardet-Biedl syndrome. Arch Ophthalmol. 2003 Jun; 121(6):804-10.
    View in: PubMed
  41. Cooper LL, Hansen RM, Darras BT, Korson M, Dougherty FE, Shoffner JM, Fulton AB. Rod photoreceptor function in children with mitochondrial disorders. Arch Ophthalmol. 2002 Aug; 120(8):1055-62.
    View in: PubMed
  42. Jiang JC, Hansen RM, Reynaud X, Fulton AB. Background adaptation in a rat model of retinopathy of prematurity. Doc Ophthalmol. 2002 Jan; 104(1):97-105.
    View in: PubMed
  43. Mayer DL, Hansen RM, Moore BD, Kim S, Fulton AB. Cycloplegic refractions in healthy children aged 1 through 48 months. Arch Ophthalmol. 2001 Nov; 119(11):1625-8.
    View in: PubMed
  44. Fulton AB, Hansen RM, Petersen RA, Vanderveen DK. The rod photoreceptors in retinopathy of prematurity: an electroretinographic study. Arch Ophthalmol. 2001 Apr; 119(4):499-505.
    View in: PubMed
  45. Hansen RM, Fulton AB. Rod-mediated increment threshold functions in infants. Invest Ophthalmol Vis Sci. 2000 Dec; 41(13):4347-52.
    View in: PubMed
  46. Fulton AB, Hansen RM. The development of scotopic sensitivity. Invest Ophthalmol Vis Sci. 2000 May; 41(6):1588-96.
    View in: PubMed
  47. Hansen RM, Fulton AB. Background adaptation in children with a history of mild retinopathy of prematurity. Invest Ophthalmol Vis Sci. 2000 Jan; 41(1):320-4.
    View in: PubMed
  48. Fulton AB, Dodge J, Hansen RM, Williams TP. The rhodopsin content of human eyes. Invest Ophthalmol Vis Sci. 1999 Jul; 40(8):1878-83.
    View in: PubMed
  49. Hansen RM, Fulton AB. The course of maturation of rod-mediated visual thresholds in infants. Invest Ophthalmol Vis Sci. 1999 Jul; 40(8):1883-6.
    View in: PubMed
  50. Timmers AM, Fox DA, He L, Hansen RM, Fulton AB. Rod photoreceptor maturation does not vary with retinal eccentricity in mammalian retina. Curr Eye Res. 1999 Jun; 18(6):393-402.
    View in: PubMed
  51. Fulton AB, Reynaud X, Hansen RM, Lemere CA, Parker C, Williams TP. Rod photoreceptors in infant rats with a history of oxygen exposure. Invest Ophthalmol Vis Sci. 1999 Jan; 40(1):168-74.
    View in: PubMed
  52. Jiang C, Hansen RM, Gee BE, Kurth SS, Fulton AB. Rod and rod mediated function in patients with beta-thalassemia major. Doc Ophthalmol. 1998-1999; 96(4):333-45.
    View in: PubMed
  53. Reisner DS, Hansen RM, Findl O, Petersen RA, Fulton AB. Dark-adapted thresholds in children with histories of mild retinopathy of prematurity. Invest Ophthalmol Vis Sci. 1997 May; 38(6):1175-83.
    View in: PubMed
  54. Dodge J, Fulton AB, Parker C, Hansen RM, Williams TP. Rhodopsin in immature rod outer segments. Invest Ophthalmol Vis Sci. 1996 Sep; 37(10):1951-6.
    View in: PubMed
  55. Fulton AB, Hansen RM, Mayer DL. Vision in Leber congenital amaurosis. Arch Ophthalmol. 1996 Jun; 114(6):698-703.
    View in: PubMed
  56. Fulton AB, Hansen RM. Photoreceptor function in infants and children with a history of mild retinopathy of prematurity. J Opt Soc Am A Opt Image Sci Vis. 1996 Mar; 13(3):566-71.
    View in: PubMed
  57. Reynaud X, Hansen RM, Fulton AB. Effect of prior oxygen exposure on the electroretinographic responses of infant rats. Invest Ophthalmol Vis Sci. 1995 Sep; 36(10):2071-9.
    View in: PubMed
  58. Fulton AB, Hansen RM, Findl O. The development of the rod photoresponse from dark-adapted rats. Invest Ophthalmol Vis Sci. 1995 May; 36(6):1038-45.
    View in: PubMed
  59. Findl O, Hansen RM, Fulton AB. The effects of acetazolamide on the electroretinographic responses in rats. Invest Ophthalmol Vis Sci. 1995 May; 36(6):1019-26.
    View in: PubMed
  60. Hansen RM, Fulton AB. Dark-adapted thresholds at 10- and 30-deg eccentricities in 10-week-old infants. Vis Neurosci. 1995 May-Jun; 12(3):509-12.
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  61. Lue CL, Hansen RM, Reisner DS, Findl O, Petersen RA, Fulton AB. The course of myopia in children with mild retinopathy of prematurity. Vision Res. 1995 May; 35(9):1329-35.
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  62. Hansen RM, Fulton AB. The VEP thresholds for full-field stimuli in dark-adapted infants. Vis Neurosci. 1995 Mar-Apr; 12(2):223-8.
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  63. Fulton AB, Hansen RM. Electroretinogram responses and refractive errors in patients with a history of retinopathy prematurity. Doc Ophthalmol. 1995-1996; 91(2):87-100.
    View in: PubMed
  64. Hansen RM, Fulton AB. Scotopic center surround organization in 10-week-old infants. Vision Res. 1994 Mar; 34(5):621-4.
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  65. Hansen RM, Fulton AB. Scotopic optokinetic nystagmus thresholds in 10-week-old infants. Invest Ophthalmol Vis Sci. 1994 Mar; 35(3):1246-9.
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  66. Fulton AB, Hansen RM, Glynn RJ. Natural course of visual functions in the Bardet-Biedl syndrome. Arch Ophthalmol. 1993 Nov; 111(11):1500-6.
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  67. Fulton AB, Hansen RM. The rod sensitivity of dark adapted human infants. Curr Eye Res. 1992 Dec; 11(12):1193-8.
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  68. Wongpichedchai S, Hansen RM, Koka B, Gudas VM, Fulton AB. Effects of halothane on children's electroretinograms. Ophthalmology. 1992 Aug; 99(8):1309-12.
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  69. Hansen RM, Hamer RD, Fulton AB. The effect of light adaptation on scotopic spatial summation in 10-week-old infants. Vision Res. 1992 Feb; 32(2):387-92.
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  70. Fulton AB, Dodge J, Hansen RM, Schremser JL, Williams TP. The quantity of rhodopsin in young human eyes. Curr Eye Res. 1991 Oct; 10(10):977-82.
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  71. Hansen RM, Fulton AB. Electroretinographic assessment of background adaptation in 10-week-old human infants. Vision Res. 1991; 31(9):1501-7.
    View in: PubMed
  72. Kurylo DD, Hansen RM, Fulton AB. Dark adapted thresholds in young RCS rats. Vision Res. 1991; 31(4):637-42.
    View in: PubMed
  73. Fulton AB, Hansen RM, Yeh YL, Tyler CW. Temporal summation in dark-adapted 10-week old infants. Vision Res. 1991; 31(7-8):1259-69.
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  74. Dagi LR, Leys MJ, Hansen RM, Fulton AB. Hyperopia in complicated Leber's congenital amaurosis. Arch Ophthalmol. 1990 May; 108(5):709-12.
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  75. Fulton AB, Greenwood V, Hansen RM, McGill MG, Russell RM, Deuster PA, Kappelman MC. Dark adaptation in hyperprolactinemic women. Invest Ophthalmol Vis Sci. 1989 Jun; 30(6):1177-80.
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  76. Fulton AB, Hartmann EE, Hansen RM. Electrophysiologic testing techniques for children. Doc Ophthalmol. 1989 Apr; 71(4):341-54.
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  77. Hansen RM, Fulton AB. Psychophysical estimates of ocular media density of human infants. Vision Res. 1989; 29(6):687-90.
    View in: PubMed
  78. Leys MJ, Schreiner LA, Hansen RM, Mayer DL, Fulton AB. Visual acuities and dark-adapted thresholds of children with Bardet-Biedl syndrome. Am J Ophthalmol. 1988 Nov 15; 106(5):561-9.
    View in: PubMed
  79. Cummings MF, van Hof-van Duin J, Mayer DL, Hansen RM, Fulton AB. Visual fields of young children. Behav Brain Res. 1988 Jul; 29(1-2):7-16.
    View in: PubMed
  80. Fulton AB, Hansen RM. Scotopic stimulus/response relations of the B-wave of the electroretinogram. Doc Ophthalmol. 1988 Mar-Apr; 68(3-4):293-304.
    View in: PubMed
  81. Fulton AB, Hansen RM. The relation of rhodopsin and scotopic retinal sensitivity in sector retinitis pigmentosa. Am J Ophthalmol. 1988 Feb 15; 105(2):132-40.
    View in: PubMed
  82. McGill MG, Schreiner LA, Hansen RM, Fulton AB. Optokinetic nystagmus thresholds of dark-adapted RCS rats. Vision Res. 1988; 28(7):761-4.
    View in: PubMed
  83. Fulton AB, Hansen RM. The relation of rhodopsin and scotopic sensitivity in choroideremia. Am J Ophthalmol. 1987 Nov 15; 104(5):524-32.
    View in: PubMed
  84. Fulton AB, Mayer DL, Hansen RM, Gagnon CA. Oscillatory potentials of visually inattentive children. Doc Ophthalmol. 1987 Mar; 65(3):319-32.
    View in: PubMed
  85. Fulton AB, Hansen RM. Foveal cone pigments and sensitivity in young patients with Usher's syndrome. Am J Ophthalmol. 1987 Feb 15; 103(2):150-60.
    View in: PubMed
  86. Fulton AB, Hansen RM. The relationship of retinal sensitivity and rhodopsin in human infants. Vision Res. 1987; 27(5):697-704.
    View in: PubMed
  87. Hansen RM, Fulton AB. Pupillary changes during dark adaptation in human infants. Invest Ophthalmol Vis Sci. 1986 Dec; 27(12):1726-9.
    View in: PubMed
  88. Harris SJ, Hansen RM, Fulton AB. Assessment of acuity of amblyopic subjects using face, grating, and recognition stimuli. Invest Ophthalmol Vis Sci. 1986 Jul; 27(7):1184-7.
    View in: PubMed
  89. Hansen RM, Fulton AB, Harris SJ. Background adaptation in human infants. Vision Res. 1986; 26(5):771-9.
    View in: PubMed
  90. Fulton AB, Hansen RM. Electroretinography: application to clinical studies of infants. J Pediatr Ophthalmol Strabismus. 1985 Nov-Dec; 22(6):251-5.
    View in: PubMed
  91. Fulton AB, Hansen RM, Harris SJ. Retinal degenerations and brain abnormalities in infants and young children. Doc Ophthalmol. 1985 Aug 30; 60(2):133-40.
    View in: PubMed
  92. Mayer DL, Fulton AB, Hansen RM. Visual acuity of infants and children with retinal degenerations. Ophthalmic Paediatr Genet. 1985 Feb; 5(1-2):51-6.
    View in: PubMed
  93. Hansen RM, Skavenski AA. Accuracy of spatial localizations near the time of saccadic eye movements. Vision Res. 1985; 25(8):1077-82.
    View in: PubMed
  94. Harris SJ, Hansen RM, Fulton AB. Assessment of acuity in human infants using face and grating stimuli. Invest Ophthalmol Vis Sci. 1984 Jul; 25(7):782-6.
    View in: PubMed
  95. Fulton AB, Hansen RM. Retinal sensitivity and adaptation in pediatric patients. Behav Brain Res. 1983 Oct; 10(1):59-70.
    View in: PubMed
  96. Manning KA, Fulton AB, Hansen RM, Mayer DL, Petersen RA, Barg DC. Preferential looking vision testing: application to evaluation of high-risk, prematurely born infants and children. J Pediatr Ophthalmol Strabismus. 1982 Nov-Dec; 19(6):286-93.
    View in: PubMed
  97. Mayer DL, Fulton AB, Hansen RM. Preferential looking acuity obtained with a staircase procedure in pediatric patients. Invest Ophthalmol Vis Sci. 1982 Oct; 23(4):538-43.
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  98. Fulton AB, Hansen RM, Underwood BA, Shwachman H, Barg DC. Scotopic thresholds and plasma retinol in cystic fibrosis. Invest Ophthalmol Vis Sci. 1982 Sep; 23(3):364-70.
    View in: PubMed
  99. Fulton AB, Hansen RM, Petersen RA. The relation of myopia and astigmatism in developing eyes. Ophthalmology. 1982 Apr; 89(4):298-302.
    View in: PubMed
  100. Hansen RM, Fulton AB. Behavioral measurement of background adaptation in infants. Invest Ophthalmol Vis Sci. 1981 Oct; 21(4):625-9.
    View in: PubMed
  101. Hansen RM, Fulton AB. Cone pigments in acute posterior multifocal placoid pigment epitheliopathy. Am J Ophthalmol. 1981 Apr; 91(4):465-8.
    View in: PubMed
  102. Fulton AB, Hansen RM, Manning KA. Measuring visual acuity in infants. Surv Ophthalmol. 1981 Mar-Apr; 25(5):325-32.
    View in: PubMed
  103. Fulton AB, Dobson V, Salem D, Mar C, Petersen RA, Hansen RM. Cycloplegic refractions in infants and young children. Am J Ophthalmol. 1980 Aug; 90(2):239-47.
    View in: PubMed
  104. Hansen RM. Spatial localization during pursuit eye movements. Vision Res. 1979; 19(11):1213-21.
    View in: PubMed
  105. Skavenski AA, Hansen RM, Steinman RM, Winterson BJ. Quality of retinal image stabilization during small natural and artificial body rotations in man. Vision Res. 1979; 19(6):675-83.
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  106. Hansen RM, Skavenski AA. Accuracy of eye position information for motor control. Vision Res. 1977; 17(8):919-26.
    View in: PubMed
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