 Darshini Kuruppu, Ph.D.
| Title | Instructor in Surgery |
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| Institution | Massachusetts General Hospital |
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| Department | Surgery |
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| Address | Massachusetts General Hospital
Dept. of Surgery
55 Fruit St
Boston MA 02114
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| Phone | 617/724-0590 |
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 Bibliographic
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications.
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Guo Y, Yuan H, Cho H, Kuruppu D, Jokivarsi K, Agarwal A, Shah K, Josephson L. High efficiency diffusion molecular retention tumor targeting. PLoS One. 2013; 8(3):e58290.
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Habibollahi P, van den Berg NS, Kuruppu D, Loda M, Mahmood U. Metformin--an Adjunct Antineoplastic Therapy--Divergently Modulates Tumor Metabolism and Proliferation, Interfering with Early Response Prediction by 18F-FDG PET Imaging. J Nucl Med. 2013 Feb; 54(2):252-8.
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Kulu Y, Kawasaki H, Donahue JM, Kasuya H, Cusack JC, Choi EW, Kuruppu DK, Fuchs BC, Tanabe KK. Concurrent chemotherapy inhibits herpes simplex virus-1 replication and oncolysis. Cancer Gene Ther. 2013 Feb; 20(2):133-40.
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Goodwin JM, Schmitt AD, McGinn CM, Fuchs BC, Kuruppu D, Tanabe KK, Lanuti M. Angiogenesis inhibition using an oncolytic herpes simplex virus expressing endostatin in a murine lung cancer model. Cancer Invest. 2012 Mar; 30(3):243-50.
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Wang JQ, Zhang Z, Kuruppu D, Brownell AL. Radiosynthesis of PET radiotracer as a prodrug for imaging group II metabotropic glutamate receptors in vivo. Bioorg Med Chem Lett. 2012 Mar 1; 22(5):1958-62.
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Lee YJ, Koch M, Karl D, Torres-Collado AX, Fernando NT, Rothrock C, Kuruppu D, Ryeom S, Iruela-Arispe ML, Yoon SS. Variable inhibition of thrombospondin 1 against liver and lung metastases through differential activation of metalloproteinase ADAMTS1. Cancer Res. 2010 Feb 1; 70(3):948-56.
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Bakirtzi K, Belfort G, Lopez-Coviella I, Kuruppu D, Cao L, Abel ED, Brownell AL, Kandror KV. Cerebellar neurons possess a vesicular compartment structurally and functionally similar to Glut4-storage vesicles from peripheral insulin-sensitive tissues. J Neurosci. 2009 Apr 22; 29(16):5193-201.
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Kulu Y, Dorfman JD, Kuruppu D, Fuchs BC, Goodwin JM, Fujii T, Kuroda T, Lanuti M, Tanabe KK. Comparison of intravenous versus intraperitoneal administration of oncolytic herpes simplex virus 1 for peritoneal carcinomatosis in mice. Cancer Gene Ther. 2009 Apr; 16(4):291-7.
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Raher MJ, Thibault HB, Buys ES, Kuruppu D, Shimizu N, Brownell AL, Blake SL, Rieusset J, Kaneki M, Derumeaux G, Picard MH, Bloch KD, Scherrer-Crosbie M. A short duration of high-fat diet induces insulin resistance and predisposes to adverse left ventricular remodeling after pressure overload. Am J Physiol Heart Circ Physiol. 2008 Dec; 295(6):H2495-502.
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Sanchez-Pernaute R, Wang JQ, Kuruppu D, Cao L, Tueckmantel W, Kozikowski A, Isacson O, Brownell AL. Enhanced binding of metabotropic glutamate receptor type 5 (mGluR5) PET tracers in the brain of parkinsonian primates. Neuroimage. 2008 Aug 1; 42(1):248-51.
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Tanabe KK, Lemoine A, Finkelstein DM, Kawasaki H, Fujii T, Chung RT, Lauwers GY, Kulu Y, Muzikansky A, Kuruppu D, Lanuti M, Goodwin JM, Azoulay D, Fuchs BC. Epidermal growth factor gene functional polymorphism and the risk of hepatocellular carcinoma in patients with cirrhosis. JAMA. 2008 Jan 2; 299(1):53-60.
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Kuruppu D, Brownell AL, Zhu A, Yu M, Wang X, Kulu Y, Fuchs BC, Kawasaki H, Tanabe KK. Positron emission tomography of herpes simplex virus 1 oncolysis. Cancer Res. 2007 Apr 1; 67(7):3295-300.
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Kuruppu D, Dorfman JD, Tanabe KK. HSV-1 viral oncolysis and molecular imaging with PET. Curr Cancer Drug Targets. 2007 Mar; 7(2):175-80.
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Kuruppu D, Tanabe KK. Viral oncolysis by herpes simplex virus and other viruses. Cancer Biol Ther. 2005 May; 4(5):524-31.
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Kasuya H, Kuruppu DK, Donahue JM, Choi EW, Kawasaki H, Tanabe KK. Mouse models of subcutaneous spleen reservoir for multiple portal venous injections to treat liver malignancies. Cancer Res. 2005 May 1; 65(9):3823-7.
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Kuruppu D, Christophi C, Maeda H, O'Brien PE. Changes in the microvascular architecture of colorectal liver metastases following the administration of SMANCS/lipiodol. J Surg Res. 2002 Mar; 103(1):47-54.
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Kuruppu D, Christophi C, Bertram JF, O'Brien PE. Tamoxifen inhibits colorectal cancer metastases in the liver: a study in a murine model. J Gastroenterol Hepatol. 1998 May; 13(5):521-7.
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Kuruppu D, Christophi C, O'Brien PE. Microvascular architecture of hepatic metastases in a mouse model. HPB Surg. 1997; 10(3):149-57; discussion 158.
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Kuruppu D, Christophi C, Bertram JF, O'Brien PE. Characterization of an animal model of hepatic metastasis. J Gastroenterol Hepatol. 1996 Jan; 11(1):26-32.
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