Contact, publication, and social network information about Harvard faculty and fellows. Harvard Catalyst Profiles
Keywords
Last Name
Institution

Hari Gopal Garg, D.SC., PH.D.

TitlePrincipal Associate in Medicine
InstitutionMassachusetts General Hospital
DepartmentMedicine
AddressMass General Hospital, East
Pulmonary Research Lab
149 13th Street
Charlestown MA 02129
Phone617/726-5632
Fax617/724-9650
Other Positions
TitleMember of the Faculty of Medicine
InstitutionMassachusetts General Hospital
DepartmentMedicine
DivisionPulmonary/Critical Care


 Bibliographic 
 selected publications
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
List All   |   Timeline
  1. Ochoa C, Garg H, Hales C, Quinn D. Low molecular weight hyaluronan, via AP-1 and NF-?B signalling, induces IL-8 in transformed bronchial epithelial cells. Swiss Med Wkly. 2011; 141:w13255.
    View in: PubMed
  2. Garg HG, Mrabat H, Yu L, Hales CA, Li B, Moore CN, Zhang F, Linhardt RJ. Anti-proliferative effects of O-acyl-low-molecular-weight heparin derivatives on bovine pulmonary artery smooth muscle cells. Glycoconj J. 2011 Aug; 28(6):419-26.
    View in: PubMed
  3. Huang PM, Syrkina O, Yu L, Dedaj R, Zhao H, Shiedlin A, Liu YY, Garg H, Quinn DA, Hales CA. High MW hyaluronan inhibits smoke inhalation-induced lung injury and improves survival. Respirology. 2010 Oct; 15(7):1131-9.
    View in: PubMed
  4. Yu L, Quinn DA, Garg HG, Hales CA. Heparin inhibits pulmonary artery smooth muscle cell proliferation through guanine nucleotide exchange factor-H1/RhoA/Rho kinase/p27. Am J Respir Cell Mol Biol. 2011 Apr; 44(4):524-30.
    View in: PubMed
  5. Zhao H, Leu SW, Shi L, Dedaj R, Zhao G, Garg HG, Shen L, Lien E, Fitzgerald KA, Shiedlin A, Shen H, Quinn DA, Hales CA. TLR4 is a negative regulator in noninfectious lung inflammation. J Immunol. 2010 May 1; 184(9):5308-14.
    View in: PubMed
  6. Garg HG, Mrabat H, Yu L, Freeman C, Li B, Zhang F, Linhardt RJ, Hales CA. Effect of carboxyl-reduced heparin on the growth inhibition of bovine pulmonary artery smooth muscle cells. Carbohydr Res. 2010 Jun 16; 345(9):1084-7.
    View in: PubMed
  7. Yu L, Garg HG, Li B, Linhardt RJ, Hales CA. Antitumor effect of butanoylated heparin with low anticoagulant activity on lung cancer growth in mice and rats. Curr Cancer Drug Targets. 2010 Mar; 10(2):229-41.
    View in: PubMed
  8. Mrabat H, Garg HG, Hales CA. Growth inhibition of bovine pulmonary artery smooth muscle cells following long-term heparin treatment. J Cell Physiol. 2009 Dec; 221(3):603-8.
    View in: PubMed
  9. Mrabat H, Beagle J, Hang Z, Garg HG, Hales CA, Quinn DA. Inhibition of HA synthase 3 mRNA expression, with a phosphodiesterase 3 inhibitor, blocks lung injury in a septic ventilated rat model. Lung. 2009 Aug; 187(4):233-9.
    View in: PubMed
  10. Liu YY, Lee CH, Dedaj R, Zhao H, Mrabat H, Sheidlin A, Syrkina O, Huang PM, Garg HG, Hales CA, Quinn DA. High-molecular-weight hyaluronan--a possible new treatment for sepsis-induced lung injury: a preclinical study in mechanically ventilated rats. Crit Care. 2008; 12(4):R102.
    View in: PubMed
  11. Garg HG, Mrabat H, Yu L, Freeman C, Li B, Zhang F, Linhardt RJ, Hales CA. Significance of the 2-O-sulfo group of L-iduronic acid residues in heparin on the growth inhibition of bovine pulmonary artery smooth muscle cells. Carbohydr Res. 2008 Sep 22; 343(14):2406-10.
    View in: PubMed
  12. Yu L, Quinn DA, Garg HG, Hales CA. Deficiency of the NHE1 gene prevents hypoxia-induced pulmonary hypertension and vascular remodeling. Am J Respir Crit Care Med. 2008 Jun 1; 177(11):1276-84.
    View in: PubMed
  13. Al-Ansari E, Du HK, Yu L, Ochoa CD, Garg HG, Quinn DA, Hales CA. Low-molecular-weight heparin inhibits hypoxic pulmonary hypertension and vascular remodeling in guinea pigs. Chest. 2007 Dec; 132(6):1898-905.
    View in: PubMed
  14. Garg HG, Hales CA, Yu L, Butler M, Islam T, Xie J, Linhardt RJ. Increase in the growth inhibition of bovine pulmonary artery smooth muscle cells by an O-hexanoyl low-molecular-weight heparin derivative. Carbohydr Res. 2006 Nov 6; 341(15):2607-12.
    View in: PubMed
  15. Yu L, Quinn DA, Garg HG, Hales CA. Gene expression of cyclin-dependent kinase inhibitors and effect of heparin on their expression in mice with hypoxia-induced pulmonary hypertension. Biochem Biophys Res Commun. 2006 Jul 14; 345(4):1565-72.
    View in: PubMed
  16. Jiang D, Liang J, Fan J, Yu S, Chen S, Luo Y, Prestwich GD, Mascarenhas MM, Garg HG, Quinn DA, Homer RJ, Goldstein DR, Bucala R, Lee PJ, Medzhitov R, Noble PW. Regulation of lung injury and repair by Toll-like receptors and hyaluronan. Nat Med. 2005 Nov; 11(11):1173-9.
    View in: PubMed
  17. Yu L, Quinn DA, Garg HG, Hales CA. Cyclin-dependent kinase inhibitor p27Kip1, but not p21WAF1/Cip1, is required for inhibition of hypoxia-induced pulmonary hypertension and remodeling by heparin in mice. Circ Res. 2005 Oct 28; 97(9):937-45.
    View in: PubMed
  18. Bai KJ, Spicer AP, Mascarenhas MM, Yu L, Ochoa CD, Garg HG, Quinn DA. The role of hyaluronan synthase 3 in ventilator-induced lung injury. Am J Respir Crit Care Med. 2005 Jul 1; 172(1):92-8.
    View in: PubMed
  19. Garg HG, Yu L, Hales CA, Toida T, Islam T, Linhardt RJ. Sulfation patterns in heparin and heparan sulfate: effects on the proliferation of bovine pulmonary artery smooth muscle cells. Biochim Biophys Acta. 2003 Nov 20; 1639(3):225-31.
    View in: PubMed
  20. Mascarenhas MM, Day RM, Ochoa CD, Choi WI, Yu L, Ouyang B, Garg HG, Hales CA, Quinn DA. Low molecular weight hyaluronan from stretched lung enhances interleukin-8 expression. Am J Respir Cell Mol Biol. 2004 Jan; 30(1):51-60.
    View in: PubMed
  21. Cindhuchao N, Quinn DA, Garg HG, Hales CA. Heparin inhibits SMC growth in the presence of human and fetal bovine serum. Biochem Biophys Res Commun. 2003 Feb 28; 302(1):84-8.
    View in: PubMed
  22. Longas MO, Garg HG, Trinkle-Pereira JM, Hales CA. Heparin antiproliferative activity on bovine pulmonary artery smooth muscle cells requires both N-acetylation and N-sulfonation. Carbohydr Res. 2003 Jan 31; 338(3):251-6.
    View in: PubMed
  23. Garg HG, Cindhuchao N, Quinn DA, Hales CA, Thanawiroon C, Capila I, Linhardt RJ. Heparin oligosaccharide sequence and size essential for inhibition of pulmonary artery smooth muscle cell proliferation. Carbohydr Res. 2002 Nov 19; 337(21-23):2359-64.
    View in: PubMed
  24. Garg HG, Thompson BT, Hales CA. Structural determinants of antiproliferative activity of heparin on pulmonary artery smooth muscle cells. Am J Physiol Lung Cell Mol Physiol. 2000 Nov; 279(5):L779-89.
    View in: PubMed
  25. Garg HG, Joseph PA, Thompson BT, Hales CA, Toida T, Imanari T, Capila I, Linhardt RJ. Effect of fully sulfated glycosaminoglycans on pulmonary artery smooth muscle cell proliferation. Arch Biochem Biophys. 1999 Nov 15; 371(2):228-33.
    View in: PubMed
  26. Quinn D, Du HK, Thompson BT, Garg HG, Hales CA. Effect of dimethyl amiloride on chronic hypoxic pulmonary hypertension in rats. Chest. 1998 Jul; 114(1 Suppl):69S-70S.
    View in: PubMed
  27. Joseph PA, Garg HG, Thompson BT, Liu X, Hales CA. Influence of molecular weight, protein core and charge of native heparin fractions on pulmonary artery smooth muscle cell proliferation. Biochem Biophys Res Commun. 1997 Dec 8; 241(1):18-23.
    View in: PubMed
  28. Garg HG, Joseph PA, Yoshida K, Thompson BT, Hales CA. Antiproliferative role of 3-O-sulfate glucosamine in heparin on cultured pulmonary artery smooth muscle cells. Biochem Biophys Res Commun. 1996 Jul 16; 224(2):468-73.
    View in: PubMed
  29. Garg HG, Siebert JW, Garg A, Neame PJ. Inseparable iduronic acid-containing proteoglycan PG(IdoA) preparations of human skin and post-burn scar tissues: evidence for elevated levels of PG(IdoA)-I in hypertrophic scar by N-terminal sequencing. Carbohydr Res. 1996 Apr 30; 284(2):223-8.
    View in: PubMed
  30. Dahlberg CG, Thompson BT, Joseph PM, Garg HG, Spence CR, Quinn DA, Bonventre JV, Hales CA. Differential effect of three commercial heparins on Na+/H+ exchange and growth of PASMC. Am J Physiol. 1996 Feb; 270(2 Pt 1):L260-5.
    View in: PubMed
  31. Cabrera RC, Siebert JW, Eidelman Y, Gold LI, Longaker MT, Garg HG. The in vivo effect of hyaluronan associated protein-collagen complex on wound repair. Biochem Mol Biol Int. 1995 Sep; 37(1):151-8.
    View in: PubMed
  32. Garg HG, Siebert JW, Garg A, Neame PJ. Iduronic acid-rich proteoglycans (PGIdoA) and human post-burn scar maturation: isolation and characterization. Carbohydr Res. 1995 Feb 1; 267(1):105-13.
    View in: PubMed
  33. Garg HG, von dem Bruch K, Kunz H. Developments in the synthesis of glycopeptides containing glycosyl L-asparagine, L-serine, and L-threonine. Adv Carbohydr Chem Biochem. 1994; 50:277-310.
    View in: PubMed
  34. Garg HG, Lippay EW, Carter EA, Donelan MB, Remensnyder JP, Siebert JW. Comparison of the effects of interleukin-1 beta on proteoglycan synthesis by human skin and post-burn normal scar explant cultures. Biochem Mol Biol Int. 1993 Nov; 31(3):583-91.
    View in: PubMed
  35. Freund RM, Siebert JW, Cabrera RC, Longaker MT, Eidelman Y, Adzick NS, Garg HG. Serial quantitation of hyaluronan and sulfated glycosaminoglycans in fetal sheep skin. Biochem Mol Biol Int. 1993 Mar; 29(4):773-83.
    View in: PubMed
  36. Longas MO, Garg HG. Sulfate composition of dermatan sulfate from scar tissue. Carbohydr Res. 1992 Dec 31; 237:319-24.
    View in: PubMed
  37. Bakshandeh N, Siebert JW, Cabrera RC, Eidelman Y, Longaker M, Freund RW, Garg HG. Isolation and partial characterization of hyaluronan-protein-collagen complex (HA-PC) from fetal sheep skin of different gestational ages. Biochem Int. 1992 Dec; 28(5):843-51.
    View in: PubMed
  38. Ueno N, Chakrabarti B, Garg HG. Hyaluronic acid of human skin and post-burn scar: heterogeneity in primary structure and molecular weight. Biochem Int. 1992 Apr; 26(5):787-96.
    View in: PubMed
  39. Garg HG, Lippay EW, Neame PJ. Proteoglycans in human burn hypertrophic scar from a patient with Ehlers-Danlos syndrome. Carbohydr Res. 1992 Jan; 223:209-20.
    View in: PubMed
  40. Garg HG, Lippay EW, Carter EA, Donelan MB, Remensnyder JP. Proteoglycan synthesis in human skin and burn scar explant cultures. Burns. 1991 Dec; 17(6):452-7.
    View in: PubMed
  41. Burd DA, Greco RM, Regauer S, Longaker MT, Siebert JW, Garg HG. Hyaluronan and wound healing: a new perspective. Br J Plast Surg. 1991 Nov-Dec; 44(8):579-84.
    View in: PubMed
  42. Garg HG, Lyon NB. Structure of collagen fibril-associated, small proteoglycans of mammalian origin. Adv Carbohydr Chem Biochem. 1991; 49:239-61.
    View in: PubMed
  43. Garg HG, Lippay EW, Burd DA, Neame PJ. Purification and characterization of iduronic acid-rich and glucuronic acid-rich proteoglycans implicated in human post-burn keloid scar. Carbohydr Res. 1990 Oct 25; 207(2):295-305.
    View in: PubMed
  44. Garg HG, Siebert EP, Swann DA. Isolation and some structure analyses of a copolymeric chondroitin sulfate-dermatan sulfate proteoglycan from post-burn, human hypertrophic scar. Carbohydr Res. 1990 Mar 25; 197:159-69.
    View in: PubMed
  45. Burd DA, Siebert JW, Ehrlich HP, Garg HG. Human skin and post-burn scar hyaluronan: demonstration of the association with collagen and other proteins. Matrix. 1989 Aug; 9(4):322-7.
    View in: PubMed
  46. Garg AK, Berg RA, Silver FH, Garg HG. Effect of proteoglycans on type I collagen fibre formation. Biomaterials. 1989 Aug; 10(6):413-9.
    View in: PubMed
  47. Swann DA, Garg HG, Hendry CJ, Hermann H, Siebert E, Sotman S, Stafford W. Isolation and partial characterization of dermatan sulfate proteoglycans from human post-burn scar tissues. Coll Relat Res. 1988 Jul; 8(4):295-313.
    View in: PubMed
  48. Garg HG, Hasenkamp T, Paulsen H. [Synthesis of xylose-containing glycopeptides that contain the amino acid sequence 4 bis 7 des NH2-terminus of the protein core structure of cattle skin proteodermatan sulfates]. Carbohydr Res. 1986 Aug 15; 151:225-32.
    View in: PubMed
  49. Swann DA, Garg HG, Jung W, Hermann H. Studies on human scar tissue proteoglycans. J Invest Dermatol. 1985 Jun; 84(6):527-31.
    View in: PubMed
  50. Garg HG, Jeanloz RW. Synthetic N- and O-glycosyl derivatives of L-asparagine, L-serine, and L-threonine. Adv Carbohydr Chem Biochem. 1985; 43:135-201.
    View in: PubMed
  51. Swann DA, Garg HG, Silver FH, Larsson A. On the structure of bovine articular cartilage high density proteoglycans. Isolation of the keratan sulfate and chondroitin sulfate side chains. J Biol Chem. 1984 Jun 25; 259(12):7693-700.
    View in: PubMed
  52. Swann DA, Garg HG, Sotman SL, Hermann H. Isolation and partial characterization of low density proteoglycans from bovine articular cartilage. J Biol Chem. 1983 Feb 25; 258(4):2683-8.
    View in: PubMed
  53. Garg HG, Swann DA. Age-related changes in the chemical composition of bovine articular cartilage. The structure of high-density proteoglycans. Biochem J. 1981 Feb 1; 193(2):459-68.
    View in: PubMed
  54. Garg HG, Jeanloz RW. Synthesis of glycopeptides containing the amino acid sequence 17-23 of bovine pancreatic deoxyribonuclease. Carbohydr Res. 1980 Nov 1; 86(1):59-68.
    View in: PubMed
  55. Garg HG, Swann DA, Glasgow LR. The structure of the O-glycosylically-linked oligosaccharide chains of LPG-I, a glycoprotein present in articular lubricating fraction of bovine synovial fluid. Carbohydr Res. 1980 Jan 1; 78(1):79-88.
    View in: PubMed
  56. Garg HG, Jeanloz RW. The synthesis of N-(benzyloxycarbonyl)-3-O-E13,4,6-tri-O-acetyl-2-deoxy-2-(2,4-dinitroanilino)-beta-D-glucopyranosyl]-L-serine methyl ester, and its condensation with activated esters of amino acids. Carbohydr Res. 1976 Dec; 52:246-50.
    View in: PubMed
  57. Garg HG, Jeanloz RW. Synthesis of subsituted glycopeptides containing at 2-acetamido-2-deoxy-beta-d-glucopyranosyl residue and the amino acid sequence 18-22 of bovine pancreatic deoxyribonuclease A. J Org Chem. 1976 Jul 9; 41(14):2480-4.
    View in: PubMed
  58. Garg HG, Jeanloz RW. The synthesis of derivatives of O-(2-acetamido-2-deoxy-D-glucopyranosyl)-L-serine. Carbohydr Res. 1976 Jul; 49:482-8.
    View in: PubMed
  59. Garg HG, Jeanloz RW. The synthesis of the 1-N-(L-aspart-4-oyl)glucosylamine linkage. New synthesis of 1-N-(L-aspart-1- and 4-oyl)-4-O-beta-D-galactopyranosyl-beta-D-glucopyranosylamines. Carbohydr Res. 1975 Sep; 43(2):371-6.
    View in: PubMed
Local representatives can answer questions about the Profiles website or help with editing a profile or issues with profile data. For assistance with this profile: HMS/HSDM faculty should contact Human Resources at faculty_serviceshms.harvard.edu.
Garg's Networks
Click the "See All" links for more information and interactive visualizations!
Concepts
See all (267) concept(s)
_
Co-Authors
See all (5) people
_
Similar People
See all (60) people
_
Same Department
Search Department
Physical Neighbors
_