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Brigid Davis, PH.D.

TitleInstructor in Medicine
InstitutionBrigham and Women's Hospital
DepartmentMedicine
AddressChanning Laboratory
181 Longwood Ave
Boston MA 02115

 Bibliographic 
 selected publications
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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  1. Munera D, Ritchie JM, Hatzios SK, Bronson R, Fang G, Schadt EE, Davis BM, Waldor MK. Autotransporters but not pAA are critical for rabbit colonization by Shiga toxin-producing Escherichia coli O104:H4. Nat Commun. 2014 Jan 20; 5:3080.
    View in: PubMed
  2. Ringgaard S, Zepeda-Rivera M, Wu X, Schirner K, Davis BM, Waldor MK. ParP prevents dissociation of CheA from chemotactic signaling arrays and tethers them to a polar anchor. Proc Natl Acad Sci U S A. 2014 Jan 14; 111(2):E255-64.
    View in: PubMed
  3. Espaillat A, Carrasco-López C, Bernardo-García N, Pietrosemoli N, Otero LH, Alvarez L, de Pedro MA, Pazos F, Davis BM, Waldor MK, Hermoso JA, Cava F. Structural basis for the broad specificity of a new family of amino-acid racemases. Acta Crystallogr D Biol Crystallogr. 2014 Jan; 70(Pt 1):79-90.
    View in: PubMed
  4. Davis BM, Waldor MK. Establishing polar identity in gram-negative rods. Curr Opin Microbiol. 2013 Dec; 16(6):752-9.
    View in: PubMed
  5. Chao MC, Pritchard JR, Zhang YJ, Rubin EJ, Livny J, Davis BM, Waldor MK. High-resolution definition of the Vibrio cholerae essential gene set with hidden Markov model-based analyses of transposon-insertion sequencing data. Nucleic Acids Res. 2013 Oct 1; 41(19):9033-48.
    View in: PubMed
  6. Dörr T, Cava F, Lam H, Davis BM, Waldor MK. Substrate specificity of an elongation-specific peptidoglycan endopeptidase and its implications for cell wall architecture and growth of Vibrio cholerae. Mol Microbiol. 2013 Sep; 89(5):949-62.
    View in: PubMed
  7. Zhou X, Gewurz BE, Ritchie JM, Takasaki K, Greenfeld H, Kieff E, Davis BM, Waldor MK. A Vibrio parahaemolyticus T3SS Effector Mediates Pathogenesis by Independently Enabling Intestinal Colonization and Inhibiting TAK1 Activation. Cell Rep. 2013 May 30; 3(5):1690-702.
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  8. Davis BM, Chao MC, Waldor MK. Entering the era of bacterial epigenomics with single molecule real time DNA sequencing. Curr Opin Microbiol. 2013 Apr; 16(2):192-8.
    View in: PubMed
  9. Davis BM, Waldor MK. Horizontal gene transfer: linking sex and cell fate. Curr Biol. 2013 Feb 4; 23(3):R118-9.
    View in: PubMed
  10. Fang G, Munera D, Friedman DI, Mandlik A, Chao MC, Banerjee O, Feng Z, Losic B, Mahajan MC, Jabado OJ, Deikus G, Clark TA, Luong K, Murray IA, Davis BM, Keren-Paz A, Chess A, Roberts RJ, Korlach J, Turner SW, Kumar V, Waldor MK, Schadt EE. Genome-wide mapping of methylated adenine residues in pathogenic Escherichia coli using single-molecule real-time sequencing. Nat Biotechnol. 2012 Dec 7; 30(12):1232-9.
    View in: PubMed
  11. Yamaichi Y, Bruckner R, Ringgaard S, Möll A, Cameron DE, Briegel A, Jensen GJ, Davis BM, Waldor MK. A multidomain hub anchors the chromosome segregation and chemotactic machinery to the bacterial pole. Genes Dev. 2012 Oct 15; 26(20):2348-60.
    View in: PubMed
  12. Mekalanos JJ, Robins W, Ussery DW, Davis BM, Schadt E, Waldor MK. Non-O1 Vibrio cholerae unlinked to cholera in Haiti. Proc Natl Acad Sci U S A. 2012 Nov 20; 109(47):E3206.
    View in: PubMed
  13. Hatzios SK, Ringgaard S, Davis BM, Waldor MK. Studies of dynamic protein-protein interactions in bacteria using Renilla luciferase complementation are undermined by nonspecific enzyme inhibition. PLoS One. 2012; 7(8):e43175.
    View in: PubMed
  14. Bashir A, Klammer AA, Robins WP, Chin CS, Webster D, Paxinos E, Hsu D, Ashby M, Wang S, Peluso P, Sebra R, Sorenson J, Bullard J, Yen J, Valdovino M, Mollova E, Luong K, Lin S, LaMay B, Joshi A, Rowe L, Frace M, Tarr CL, Turnsek M, Davis BM, Kasarskis A, Mekalanos JJ, Waldor MK, Schadt EE. A hybrid approach for the automated finishing of bacterial genomes. Nat Biotechnol. 2012 Jul; 30(7):701-7.
    View in: PubMed
  15. Zhou X, Ritchie JM, Hiyoshi H, Iida T, Davis BM, Waldor MK, Kodama T. The hydrophilic translocator for Vibrio parahaemolyticus, T3SS2, is also translocated. Infect Immun. 2012 Aug; 80(8):2940-7.
    View in: PubMed
  16. Ritchie JM, Rui H, Zhou X, Iida T, Kodoma T, Ito S, Davis BM, Bronson RT, Waldor MK. Inflammation and disintegration of intestinal villi in an experimental model for Vibrio parahaemolyticus-induced diarrhea. PLoS Pathog. 2012; 8(3):e1002593.
    View in: PubMed
  17. Ritchie JM, Greenwich JL, Davis BM, Bronson RT, Gebhart D, Williams SR, Martin D, Scholl D, Waldor MK. An Escherichia coli O157-specific engineered pyocin prevents and ameliorates infection by E. coli O157:H7 in an animal model of diarrheal disease. Antimicrob Agents Chemother. 2011 Dec; 55(12):5469-74.
    View in: PubMed
  18. Cava F, de Pedro MA, Lam H, Davis BM, Waldor MK. Distinct pathways for modification of the bacterial cell wall by non-canonical D-amino acids. EMBO J. 2011 Aug 17; 30(16):3442-53.
    View in: PubMed
  19. Yamaichi Y, Gerding MA, Davis BM, Waldor MK. Regulatory cross-talk links Vibrio cholerae chromosome II replication and segregation. PLoS Genet. 2011 Jul; 7(7):e1002189.
    View in: PubMed
  20. Ringgaard S, Schirner K, Davis BM, Waldor MK. A family of ParA-like ATPases promotes cell pole maturation by facilitating polar localization of chemotaxis proteins. Genes Dev. 2011 Jul 15; 25(14):1544-55.
    View in: PubMed
  21. Le Roux F, Davis BM, Waldor MK. Conserved small RNAs govern replication and incompatibility of a diverse new plasmid family from marine bacteria. Nucleic Acids Res. 2011 Feb; 39(3):1004-13.
    View in: PubMed
  22. Le Roux F, Labreuche Y, Davis BM, Iqbal N, Mangenot S, Goarant C, Mazel D, Waldor MK. Virulence of an emerging pathogenic lineage of Vibrio nigripulchritudo is dependent on two plasmids. Environ Microbiol. 2011 Feb; 13(2):296-306.
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  23. Shakhnovich EA, Davis BM, Waldor MK. Hfq negatively regulates type III secretion in EHEC and several other pathogens. Mol Microbiol. 2009 Oct; 74(2):347-63.
    View in: PubMed
  24. Davis BM, Waldor MK. High-throughput sequencing reveals suppressors of Vibrio cholerae rpoE mutations: one fewer porin is enough. Nucleic Acids Res. 2009 Sep; 37(17):5757-67.
    View in: PubMed
  25. Ho TD, Davis BM, Ritchie JM, Waldor MK. Type 2 secretion promotes enterohemorrhagic Escherichia coli adherence and intestinal colonization. Infect Immun. 2008 May; 76(5):1858-65.
    View in: PubMed
  26. Davis BM, Waldor MK. RNase E-dependent processing stabilizes MicX, a Vibrio cholerae sRNA. Mol Microbiol. 2007 Jul; 65(2):373-85.
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  27. Mathur J, Davis BM, Waldor MK. Antimicrobial peptides activate the Vibrio cholerae sigmaE regulon through an OmpU-dependent signalling pathway. Mol Microbiol. 2007 Feb; 63(3):848-58.
    View in: PubMed
  28. Budde PP, Davis BM, Yuan J, Waldor MK. Characterization of a higBA toxin-antitoxin locus in Vibrio cholerae. J Bacteriol. 2007 Jan; 189(2):491-500.
    View in: PubMed
  29. Quinones M, Davis BM, Waldor MK. Activation of the Vibrio cholerae SOS response is not required for intestinal cholera toxin production or colonization. Infect Immun. 2006 Feb; 74(2):927-30.
    View in: PubMed
  30. Livny J, Fogel MA, Davis BM, Waldor MK. sRNAPredict: an integrative computational approach to identify sRNAs in bacterial genomes. Nucleic Acids Res. 2005; 33(13):4096-105.
    View in: PubMed
  31. McLeod SM, Kimsey HH, Davis BM, Waldor MK. CTXphi and Vibrio cholerae: exploring a newly recognized type of phage-host cell relationship. Mol Microbiol. 2005 Jul; 57(2):347-56.
    View in: PubMed
  32. Davis BM, Quinones M, Pratt J, Ding Y, Waldor MK. Characterization of the small untranslated RNA RyhB and its regulon in Vibrio cholerae. J Bacteriol. 2005 Jun; 187(12):4005-14.
    View in: PubMed
  33. Ding Y, Davis BM, Waldor MK. Hfq is essential for Vibrio cholerae virulence and downregulates sigma expression. Mol Microbiol. 2004 Jul; 53(1):345-54.
    View in: PubMed
  34. Davis BM, Waldor MK. Filamentous phages linked to virulence of Vibrio cholerae. Curr Opin Microbiol. 2003 Feb; 6(1):35-42.
    View in: PubMed
  35. Davis BM, Kimsey HH, Kane AV, Waldor MK. A satellite phage-encoded antirepressor induces repressor aggregation and cholera toxin gene transfer. EMBO J. 2002 Aug 15; 21(16):4240-9.
    View in: PubMed
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