David Marc Weinstock, M.D.
|Title||Assistant Professor of Medicine|
|Institution||Dana-Farber Cancer Institute|
|Address||Dana Farber Cancer Institute|
Department of Medical Oncology, D510B
44 Binney St
Boston MA 02115
2012||Career Award in the Biomedical Sciences|
2007||Young Investigator Award|
2013||Innovative Research Grant|
2012||Junior Faculty Research Award|
The Weinstock laboratory uses a combination of in vitro and in vivo approaches to identify and characterize novel aberrations in human tumors. In addition, the laboratory studies the relationship between aberrant DNA repair and tumorigenesis in cell lines, primary patient material and pluirpotent stem cells.
Available: 07/01/12, Expires: 06/30/15
The student would be a leader in a translational research effort to identify oncogene abnormalities directly from leukemia and lymphoma specimens. The approaches combine next-generation sequencing with functional mRNA transcript interrogation to identify mutant sequences that confer malignant phenotypes. The laboratory has used this approach to define novel oncogenes in lymphoid malignancies, and then determined epidemiology, function and prognostic implications for cases with this aberration. The project involves multiple collaborations with clinical and basic science investigators that would add to the breadth of experience for the student.
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