Gail Kurr Adler, PH.D., M.D.
|Title||Associate Professor of Medicine|
|Institution||Brigham and Women's Hospital|
|Address||Brigham and Women's Hospital|
221 Longwood Ave
Boston MA 02115
Available: 08/15/11, Expires: 08/15/15
Clinical research projects:
1. To test the hypothesis that exposure to hypoglycemia impairs autonomic control of cardiovascular function through activation of the mineralocorticoid receptor. These studies in humans involve the performance of hyperinsulinemic hypoglycemic clamps and autonomic testing (modified oxford, lower body negative pressure).
2. To test the hypothesis that blockade of the mineralocorticoid receptor will improve cardiac function in patients with diabetes. These studies involve patients with diabetes and the performance of cardiac PET and cardiac MRI.
Basic Research Studies:
1. To identify proteins that interact with the mineralocorticoid receptor to alter the genomic and nongenomic actions of aldosterone and thus affect cardiovascular risk. Studies are performed in cells and genetically modified mice.
Interactions Between the Hypothalamic-Pituary-Adrenal Axis and the Autonomic Nervous System in Women with Fibromyalgia
Part Time, 09/06/01 - 12/20/01
Immunoneuroendocrine Response to a Tetanus Toxoid Immune Challenge in Patients with Fibromyalgia
Part Time, 10/15/99 - 04/30/99
Interactions Between the Hypothalamic-Pituitary-Adrenal Axis ad the Autonomic NErvous System in Women with Fibromyalgia
Part Time, 03/26/01 - 06/15/01
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