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Christopher H. Evans, D.SC., PH.D.

TitleMaurice Edmond Mueller Professor of Orthopedic Surgery, Emeritus
InstitutionBeth Israel Deaconess Medical Center
DepartmentEmeritus
AddressBeth Israel Deaconess Medical Center
O B L 115
330 Brookline Ave
Boston MA 02215
Phone617/667-2940
Fax617/667-7175

 Bibliographic 
 selected publications
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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  1. Evans CH, Kraus VB, Setton LA. Progress in intra-articular therapy. Nat Rev Rheumatol. 2014 Jan; 10(1):11-22.
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  2. Evans CH. Advances in regenerative orthopedics. Mayo Clin Proc. 2013 Nov; 88(11):1323-39.
    View in: PubMed
  3. Ferreira E, Porter RM, Wehling N, O'Sullivan RP, Liu F, Boskey A, Estok DM, Harris MB, Vrahas MS, Evans CH, Wells JW. Inflammatory cytokines induce a unique mineralizing phenotype in mesenchymal stem cells derived from human bone marrow. J Biol Chem. 2013 Oct 11; 288(41):29494-505.
    View in: PubMed
  4. Evans CH. Platelet-Rich Plasma à la Carte: Commentary on an article by Satoshi Terada, MD, et al.: "Use of an Antifibrotic Agent Improves the Effect of Platelet-Rich Plasma on Muscle Healing After Injury". J Bone Joint Surg Am. 2013 Jun 5; 95(11):e801-2.
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  5. Vo N, Niedernhofer LJ, Nasto LA, Jacobs L, Robbins PD, Kang J, Evans CH. An overview of underlying causes and animal models for the study of age-related degenerative disorders of the spine and synovial joints. J Orthop Res. 2013 Jun; 31(6):831-7.
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  6. Evans CH, Ghivizzani SC, Robbins PD. Arthritis gene therapy and its tortuous path into the clinic. Transl Res. 2013 Apr; 161(4):205-16.
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  7. Wells JW, Evans CH, Scott MC, Rütgen BC, O'Brien TD, Modiano JF, Cvetkovic G, Tepic S. Arginase treatment prevents the recovery of canine lymphoma and osteosarcoma cells resistant to the toxic effects of prolonged arginine deprivation. PLoS One. 2013; 8(1):e54464.
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  8. Evans CH, Liu F, Porter RM, O'Sullivan RP, Merghoub T, Lunsford EP, Robichaud K, Van Valen F, Lessnick SL, Gebhardt MC, Wells JW. EWS-FLI-1-targeted cytotoxic T-cell killing of multiple tumor types belonging to the Ewing sarcoma family of tumors. Clin Cancer Res. 2012 Oct 1; 18(19):5341-51.
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  9. Glatt V, Evans CH, Matthys R. Design, characterisation and in vivo testing of a new, adjustable stiffness, external fixator for the rat femur. Eur Cell Mater. 2012; 23:289-98; discussion 299.
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  10. Evans CH. Gene delivery to bone. Adv Drug Deliv Rev. 2012 Sep; 64(12):1331-40.
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  11. Majewski M, Porter RM, Betz OB, Betz VM, Clahsen H, Flückiger R, Evans CH. Improvement of tendon repair using muscle grafts transduced with TGF-ß1 cDNA. Eur Cell Mater. 2012; 23:94-101; discussion 101-2.
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  12. Evans CH, Ghivizzani SC, Robbins PD. Orthopedic gene therapy--lost in translation? J Cell Physiol. 2012 Feb; 227(2):416-20.
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  13. Liu F, Porter RM, Wells J, Glatt V, Pilapil C, Evans CH. Evaluation of BMP-2 gene-activated muscle grafts for cranial defect repair. J Orthop Res. 2012 Jul; 30(7):1095-102.
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  14. Heisterbach PE, Todorov A, Flückiger R, Evans CH, Majewski M. Effect of BMP-12, TGF-ß1 and autologous conditioned serum on growth factor expression in Achilles tendon healing. Knee Surg Sports Traumatol Arthrosc. 2012 Oct; 20(10):1907-14.
    View in: PubMed
  15. Lu YC, Evans CH, Grodzinsky AJ. Effects of short-term glucocorticoid treatment on changes in cartilage matrix degradation and chondrocyte gene expression induced by mechanical injury and inflammatory cytokines. Arthritis Res Ther. 2011; 13(5):R142.
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  16. Evans CH. Barriers to the clinical translation of orthopedic tissue engineering. Tissue Eng Part B Rev. 2011 Dec; 17(6):437-41.
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  17. Ivkovic A, Marijanovic I, Hudetz D, Porter RM, Pecina M, Evans CH. Regenerative medicine and tissue engineering in orthopaedic surgery. Front Biosci (Elite Ed). 2011; 3:923-44.
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  18. Evans C. Gene therapy for the regeneration of bone. Injury. 2011 Jun; 42(6):599-604.
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  19. Steinert AF, Kunz M, Prager P, Barthel T, Jakob F, Nöth U, Murray MM, Evans CH, Porter RM. Mesenchymal stem cell characteristics of human anterior cruciate ligament outgrowth cells. Tissue Eng Part A. 2011 May; 17(9-10):1375-88.
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  20. Evans CH, Ghivizzani SC, Robbins PD. Getting arthritis gene therapy into the clinic. Nat Rev Rheumatol. 2011 Apr; 7(4):244-9.
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  21. Haddad-Weber M, Prager P, Kunz M, Seefried L, Jakob F, Murray MM, Evans CH, Nöth U, Steinert AF. BMP12 and BMP13 gene transfer induce ligamentogenic differentiation in mesenchymal progenitor and anterior cruciate ligament cells. Cytotherapy. 2010 Jul; 12(4):505-13.
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  22. Evans CH. Gene therapy for bone healing. Expert Rev Mol Med. 2010; 12:e18.
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  23. Miller MA, Ivkovic A, Porter R, Harris MB, Estok DM, Smith RM, Evans CH, Vrahas MS. Autologous bone grafting on steroids: preliminary clinical results. A novel treatment for nonunions and segmental bone defects. Int Orthop. 2011 Apr; 35(4):599-605.
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  24. Nazarian A, Pezzella L, Tseng A, Baldassarri S, Zurakowski D, Evans CH, Snyder BD. Application of structural rigidity analysis to assess fidelity of healed fractures in rat femurs with critical defects. Calcif Tissue Int. 2010 May; 86(5):397-403.
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  25. Evans CH, Liu FJ, Glatt V, Hoyland JA, Kirker-Head C, Walsh A, Betz O, Wells JW, Betz V, Porter RM, Saad FA, Gerstenfeld LC, Einhorn TA, Harris MB, Vrahas MS. Use of genetically modified muscle and fat grafts to repair defects in bone and cartilage. Eur Cell Mater. 2009; 18:96-111.
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  26. Lefèvre S, Knedla A, Tennie C, Kampmann A, Wunrau C, Dinser R, Korb A, Schnäker EM, Tarner IH, Robbins PD, Evans CH, Stürz H, Steinmeyer J, Gay S, Schölmerich J, Pap T, Müller-Ladner U, Neumann E. Synovial fibroblasts spread rheumatoid arthritis to unaffected joints. Nat Med. 2009 Dec; 15(12):1414-20.
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  27. Majewski M, Ochsner PE, Liu F, Flückiger R, Evans CH. Accelerated healing of the rat Achilles tendon in response to autologous conditioned serum. Am J Sports Med. 2009 Nov; 37(11):2117-25.
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  28. Glatt V, Kwong FN, Park K, Parry N, Griffin D, Vrahas M, Evans CH, Harris M. Ability of recombinant human bone morphogenetic protein 2 to enhance bone healing in the presence of tobramycin: evaluation in a rat segmental defect model. J Orthop Trauma. 2009 Nov-Dec; 23(10):693-701.
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  29. Steinert AF, Proffen B, Kunz M, Hendrich C, Ghivizzani SC, Nöth U, Rethwilm A, Eulert J, Evans CH. Hypertrophy is induced during the in vitro chondrogenic differentiation of human mesenchymal stem cells by bone morphogenetic protein-2 and bone morphogenetic protein-4 gene transfer. Arthritis Res Ther. 2009; 11(5):R148.
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  30. Evans CH, Ghivizzani SC, Robbins PD. Progress and Prospects: genetic treatments for disorders of bones and joints. Gene Ther. 2009 Aug; 16(8):944-52.
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  31. Kay JD, Gouze E, Oligino TJ, Gouze JN, Watson RS, Levings PP, Bush ML, Dacanay A, Nickerson DM, Robbins PD, Evans CH, Ghivizzani SC. Intra-articular gene delivery and expression of interleukin-1Ra mediated by self-complementary adeno-associated virus. J Gene Med. 2009 Jul; 11(7):605-14.
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  32. Kwong FN, Hoyland JA, Freemont AJ, Evans CH. Altered relative expression of BMPs and BMP inhibitors in cartilaginous areas of human fractures progressing towards nonunion. J Orthop Res. 2009 Jun; 27(6):752-7.
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  33. Steinert AF, Palmer GD, Pilapil C, Nöth U, Evans CH, Ghivizzani SC. Enhanced in vitro chondrogenesis of primary mesenchymal stem cells by combined gene transfer. Tissue Eng Part A. 2009 May; 15(5):1127-39.
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  34. Wehling N, Palmer GD, Pilapil C, Liu F, Wells JW, Müller PE, Evans CH, Porter RM. Interleukin-1beta and tumor necrosis factor alpha inhibit chondrogenesis by human mesenchymal stem cells through NF-kappaB-dependent pathways. Arthritis Rheum. 2009 Mar; 60(3):801-12.
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  35. Wehling P, Reinecke J, Baltzer AW, Granrath M, Schulitz KP, Schultz C, Krauspe R, Whiteside TW, Elder E, Ghivizzani SC, Robbins PD, Evans CH. Clinical responses to gene therapy in joints of two subjects with rheumatoid arthritis. Hum Gene Ther. 2009 Feb; 20(2):97-101.
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  36. Evans CH, Ghivizzani SC, Robbins PD. Gene therapy of the rheumatic diseases: 1998 to 2008. Arthritis Res Ther. 2009; 11(1):209.
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  37. Porter RM, Liu F, Pilapil C, Betz OB, Vrahas MS, Harris MB, Evans CH. Osteogenic potential of reamer irrigator aspirator (RIA) aspirate collected from patients undergoing hip arthroplasty. J Orthop Res. 2009 Jan; 27(1):42-9.
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  38. Evans CH, Ghivizzani SC, Robbins PD. Orthopedic gene therapy in 2008. Mol Ther. 2009 Feb; 17(2):231-44.
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  39. Kwong FN, Hoyland JA, Evans CH, Freemont AJ. Regional and cellular localisation of BMPs and their inhibitors' expression in human fractures. Int Orthop. 2009 Feb; 33(1):281-8.
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  40. Ghivizzani SC, Gouze E, Gouze JN, Kay JD, Bush ML, Watson RS, Levings PP, Nickerson DM, Colahan PT, Robbins PD, Evans CH. Perspectives on the use of gene therapy for chronic joint diseases. Curr Gene Ther. 2008 Aug; 8(4):273-86.
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  41. Kwong FN, Richardson SM, Evans CH. Chordin knockdown enhances the osteogenic differentiation of human mesenchymal stem cells. Arthritis Res Ther. 2008; 10(3):R65.
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  42. Evans CH, Ghivizzani SC, Robbins PD. Arthritis gene therapy's first death. Arthritis Res Ther. 2008; 10(3):110.
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  43. Majewski M, Betz O, Ochsner PE, Liu F, Porter RM, Evans CH. Ex vivo adenoviral transfer of bone morphogenetic protein 12 (BMP-12) cDNA improves Achilles tendon healing in a rat model. Gene Ther. 2008 Aug; 15(16):1139-46.
    View in: PubMed
  44. Kisiday JD, Kopesky PW, Evans CH, Grodzinsky AJ, McIlwraith CW, Frisbie DD. Evaluation of adult equine bone marrow- and adipose-derived progenitor cell chondrogenesis in hydrogel cultures. J Orthop Res. 2008 Mar; 26(3):322-31.
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  45. Palmer GD, Stoddart MJ, Gouze E, Gouze JN, Ghivizzani SC, Porter RM, Evans CH. A simple, lanthanide-based method to enhance the transduction efficiency of adenovirus vectors. Gene Ther. 2008 Mar; 15(5):357-63.
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  46. Betz VM, Betz OB, Harris MB, Vrahas MS, Evans CH. Bone tissue engineering and repair by gene therapy. Front Biosci. 2008; 13:833-41.
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  47. Steinert AF, Weber M, Kunz M, Palmer GD, Nöth U, Evans CH, Murray MM. In situ IGF-1 gene delivery to cells emerging from the injured anterior cruciate ligament. Biomaterials. 2008 Mar; 29(7):904-16.
    View in: PubMed
  48. Betz VM, Betz OB, Glatt V, Gerstenfeld LC, Einhorn TA, Bouxsein ML, Vrahas MS, Evans CH. Healing of segmental bone defects by direct percutaneous gene delivery: effect of vector dose. Hum Gene Ther. 2007 Oct; 18(10):907-15.
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  49. Steinert AF, Palmer GD, Capito R, Hofstaetter JG, Pilapil C, Ghivizzani SC, Spector M, Evans CH. Genetically enhanced engineering of meniscus tissue using ex vivo delivery of transforming growth factor-beta 1 complementary deoxyribonucleic acid. Tissue Eng. 2007 Sep; 13(9):2227-37.
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  50. Evans CH, Palmer GD, Pascher A, Porter R, Kwong FN, Gouze E, Gouze JN, Liu F, Steinert A, Betz O, Betz V, Vrahas M, Ghivizzani SC. Facilitated endogenous repair: making tissue engineering simple, practical, and economical. Tissue Eng. 2007 Aug; 13(8):1987-93.
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  51. Simon LS, Evans C, Katz N, Bombardier C, West C, Robbins J, Copley-Merriman C, Markman J, Coombs JH. Preliminary development of a responder index for chronic low back pain. J Rheumatol. 2007 Jun; 34(6):1386-91.
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  52. Goodrich LR, Hidaka C, Robbins PD, Evans CH, Nixon AJ. Genetic modification of chondrocytes with insulin-like growth factor-1 enhances cartilage healing in an equine model. J Bone Joint Surg Br. 2007 May; 89(5):672-85.
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  53. Betz OB, Betz VM, Nazarian A, Egermann M, Gerstenfeld LC, Einhorn TA, Vrahas MS, Bouxsein ML, Evans CH. Delayed administration of adenoviral BMP-2 vector improves the formation of bone in osseous defects. Gene Ther. 2007 Jul; 14(13):1039-44.
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  54. Gouze E, Gouze JN, Palmer GD, Pilapil C, Evans CH, Ghivizzani SC. Transgene persistence and cell turnover in the diarthrodial joint: implications for gene therapy of chronic joint diseases. Mol Ther. 2007 Jun; 15(6):1114-20.
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  55. Evans CH. John Hunter and the origins of modern orthopaedic research. J Orthop Res. 2007 Apr; 25(4):556-60.
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  56. Gouze JN, Evans CH, Ghivizzani SC, Gouze E. [Gene therapy for osteoarticular disorders]. Med Sci (Paris). 2007 Mar; 23(3):303-9.
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  57. Steinert AF, Ghivizzani SC, Rethwilm A, Tuan RS, Evans CH, Nöth U. Major biological obstacles for persistent cell-based regeneration of articular cartilage. Arthritis Res Ther. 2007; 9(3):213.
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  58. Evans CH, Ghivizzani SC, Robbins PD. Will arthritis gene therapy become a clinical reality? Nat Clin Pract Rheumatol. 2006 Jul; 2(7):344-5.
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  59. Meinel L, Hofmann S, Betz O, Fajardo R, Merkle HP, Langer R, Evans CH, Vunjak-Novakovic G, Kaplan DL. Osteogenesis by human mesenchymal stem cells cultured on silk biomaterials: comparison of adenovirus mediated gene transfer and protein delivery of BMP-2. Biomaterials. 2006 Oct; 27(28):4993-5002.
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  60. Evans CH, Ghivizzani SC, Robbins PD. Gene therapy for arthritis: what next? Arthritis Rheum. 2006 Jun; 54(6):1714-29.
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  61. Goodrich LR, Brower-Toland BD, Warnick L, Robbins PD, Evans CH, Nixon AJ. Direct adenovirus-mediated IGF-I gene transduction of synovium induces persisting synovial fluid IGF-I ligand elevations. Gene Ther. 2006 Sep; 13(17):1253-62.
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  62. Egermann M, Lill CA, Griesbeck K, Evans CH, Robbins PD, Schneider E, Baltzer AW. Effect of BMP-2 gene transfer on bone healing in sheep. Gene Ther. 2006 Sep; 13(17):1290-9.
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  63. Evans C. Potential biologic therapies for the intervertebral disc. J Bone Joint Surg Am. 2006 Apr; 88 Suppl 2:95-8.
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  64. Evans CH, Gouze E, Gouze JN, Robbins PD, Ghivizzani SC. Gene therapeutic approaches-transfer in vivo. Adv Drug Deliv Rev. 2006 May 20; 58(2):243-58.
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  65. Betz OB, Betz VM, Nazarian A, Pilapil CG, Vrahas MS, Bouxsein ML, Gerstenfeld LC, Einhorn TA, Evans CH. Direct percutaneous gene delivery to enhance healing of segmental bone defects. J Bone Joint Surg Am. 2006 Feb; 88(2):355-65.
    View in: PubMed
  66. van Stam J, Viaene L, Evans CH. Tuning of the alpha-terthiophene radical cation coupling reaction using mixed micelles with varying charge density. Chemphyschem. 2005 Nov 11; 6(11):2428-33.
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  67. Evans CH, Rosier RN. Molecular biology in orthopaedics: the advent of molecular orthopaedics. J Bone Joint Surg Am. 2005 Nov; 87(11):2550-64.
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  68. Evans CH, Ghivizzani SC, Gouze E, Rediske JJ, Schwarz EM, Robbins PD. The 3rd International Meeting on Gene Therapy in Rheumatology and Orthopaedics. Arthritis Res Ther. 2005; 7(6):273-8.
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  69. Palmer GD, Steinert A, Pascher A, Gouze E, Gouze JN, Betz O, Johnstone B, Evans CH, Ghivizzani SC. Gene-induced chondrogenesis of primary mesenchymal stem cells in vitro. Mol Ther. 2005 Aug; 12(2):219-28.
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  70. Evans CH, Ghivizzani SC, Herndon JH, Robbins PD. Gene therapy for the treatment of musculoskeletal diseases. J Am Acad Orthop Surg. 2005 Jul-Aug; 13(4):230-42.
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  71. Evans CH, Robbins PD, Ghivizzani SC, Wasko MC, Tomaino MM, Kang R, Muzzonigro TA, Vogt M, Elder EM, Whiteside TL, Watkins SC, Herndon JH. Gene transfer to human joints: progress toward a gene therapy of arthritis. Proc Natl Acad Sci U S A. 2005 Jun 14; 102(24):8698-703.
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  72. Egermann M, Schneider E, Evans CH, Baltzer AW. The potential of gene therapy for fracture healing in osteoporosis. Osteoporos Int. 2005 Mar; 16 Suppl 2:S120-8.
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  73. Haupt JL, Frisbie DD, McIlwraith CW, Robbins PD, Ghivizzani S, Evans CH, Nixon AJ. Dual transduction of insulin-like growth factor-I and interleukin-1 receptor antagonist protein controls cartilage degradation in an osteoarthritic culture model. J Orthop Res. 2005 Jan; 23(1):118-26.
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  74. Evans CH. Gene therapy: what have we accomplished and where do we go from here? J Rheumatol Suppl. 2005 Jan; 72:17-20.
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  75. Evans CH. Novel biological approaches to the intra-articular treatment of osteoarthritis. BioDrugs. 2005; 19(6):355-62.
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  76. Nixon AJ, Haupt JL, Frisbie DD, Morisset SS, McIlwraith CW, Robbins PD, Evans CH, Ghivizzani S. Gene-mediated restoration of cartilage matrix by combination insulin-like growth factor-I/interleukin-1 receptor antagonist therapy. Gene Ther. 2005 Jan; 12(2):177-86.
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  77. Evans CH, Ghivizzani SC, Robbins PD. The 2003 Nicolas Andry Award. Orthopaedic gene therapy. Clin Orthop Relat Res. 2004 Dec; (429):316-29.
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  78. Agarwal S, Deschner J, Long P, Verma A, Hofman C, Evans CH, Piesco N. Role of NF-kappaB transcription factors in antiinflammatory and proinflammatory actions of mechanical signals. Arthritis Rheum. 2004 Nov; 50(11):3541-8.
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  79. Pascher A, Steinert AF, Palmer GD, Betz O, Gouze JN, Gouze E, Pilapil C, Ghivizzani SC, Evans CH, Murray MM. Enhanced repair of the anterior cruciate ligament by in situ gene transfer: evaluation in an in vitro model. Mol Ther. 2004 Aug; 10(2):327-36.
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  80. Lattermann C, Baltzer AW, Zelle BA, Whalen JD, Niyibizi C, Robbins PD, Evans CH, Gruen GS. Feasibility of percutaneous gene transfer to an atrophic nonunion in a rabbit. Clin Orthop Relat Res. 2004 Aug; (425):237-43.
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  81. Evans CH. On the TRAIL of an arthritis cure. Gene Ther. 2004 May; 11(9):735-6.
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  82. Lattermann C, Zelle BA, Whalen JD, Baltzer AW, Robbins PD, Niyibizi C, Evans CH, Fu FH. Gene transfer to the tendon-bone insertion site. Knee Surg Sports Traumatol Arthrosc. 2004 Sep; 12(5):510-5.
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  83. Gouze JN, Gouze E, Palmer GD, Kaneto H, Ghivizzani SC, Grodzinsky AJ, Evans CH. Adenovirus-mediated gene transfer of glutamine: fructose-6-phosphate amidotransferase antagonizes the effects of interleukin-1beta on rat chondrocytes. Osteoarthritis Cartilage. 2004 Mar; 12(3):217-24.
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  84. Yang SY, Wu B, Mayton L, Mukherjee P, Robbins PD, Evans CH, Wooley PH. Protective effects of IL-1Ra or vIL-10 gene transfer on a murine model of wear debris-induced osteolysis. Gene Ther. 2004 Mar; 11(5):483-91.
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  85. Evans CH, Gouze JN, Gouze E, Robbins PD, Ghivizzani SC. Osteoarthritis gene therapy. Gene Ther. 2004 Feb; 11(4):379-89.
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  86. Evans CH. Orthopaedics: gene therapy's dark horse. Gene Ther. 2004 Feb; 11(4):343.
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  87. Evans CH. Gene therapies for osteoarthritis. Curr Rheumatol Rep. 2004 Feb; 6(1):31-40.
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  88. Southwood LL, Frisbie DD, Kawcak CE, Ghivizzani SC, Evans CH, McIlwraith CW. Evaluation of Ad-BMP-2 for enhancing fracture healing in an infected defect fracture rabbit model. J Orthop Res. 2004 Jan; 22(1):66-72.
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  89. Gouze JN, Stoddart MJ, Gouze E, Palmer GD, Ghivizzani SC, Grodzinsky AJ, Evans CH. In vitro gene transfer to chondrocytes and synovial fibroblasts by adenoviral vectors. Methods Mol Med. 2004; 100:147-64.
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  90. Pascher A, Palmer GD, Steinert A, Oligino T, Gouze E, Gouze JN, Betz O, Spector M, Robbins PD, Evans CH, Ghivizzani SC. Gene delivery to cartilage defects using coagulated bone marrow aspirate. Gene Ther. 2004 Jan; 11(2):133-41.
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  91. Gouze JN, Gouze E, Palmer GD, Liew VS, Pascher A, Betz OB, Thornhill TS, Evans CH, Grodzinsky AJ, Ghivizzani SC. A comparative study of the inhibitory effects of interleukin-1 receptor antagonist following administration as a recombinant protein or by gene transfer. Arthritis Res Ther. 2003; 5(5):R301-9.
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  92. Yao Q, Wang S, Gambotto A, Glorioso JC, Evans CH, Robbins PD, Ghivizzani SC, Oligino TJ. Intra-articular adenoviral-mediated gene transfer of trail induces apoptosis of arthritic rabbit synovium. Gene Ther. 2003 Jun; 10(12):1055-60.
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  93. Robbins PD, Evans CH, Chernajovsky Y. Gene therapy for arthritis. Gene Ther. 2003 May; 10(10):902-11.
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  94. Gouze E, Pawliuk R, Gouze JN, Pilapil C, Fleet C, Palmer GD, Evans CH, Leboulch P, Ghivizzani SC. Lentiviral-mediated gene delivery to synovium: potent intra-articular expression with amplification by inflammation. Mol Ther. 2003 Apr; 7(4):460-6.
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  95. Mi Z, Ghivizzani SC, Lechman E, Glorioso JC, Evans CH, Robbins PD. Adverse effects of adenovirus-mediated gene transfer of human transforming growth factor beta 1 into rabbit knees. Arthritis Res Ther. 2003; 5(3):R132-9.
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  96. Palmer GD, Gouze E, Gouze JN, Betz OB, Evans CH, Ghivizzani SC. Gene transfer to articular chondrocytes with recombinant adenovirus. Methods Mol Biol. 2003; 215:235-46.
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  97. Neumann E, Judex M, Kullmann F, Grifka J, Robbins PD, Pap T, Gay RE, Evans CH, Gay S, Schölmerich J, Müller-Ladner U. Inhibition of cartilage destruction by double gene transfer of IL-1Ra and IL-10 involves the activin pathway. Gene Ther. 2002 Nov; 9(22):1508-19.
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  98. Maffulli N, Moller HD, Evans CH. Tendon healing: can it be optimised? Br J Sports Med. 2002 Oct; 36(5):315-6.
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  99. Lieberman JR, Ghivizzani SC, Evans CH. Gene transfer approaches to the healing of bone and cartilage. Mol Ther. 2002 Aug; 6(2):141-7.
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  100. Yang S, Wu B, Mayton L, Evans CH, Robbins PD, Wooley PH. IL-1Ra and vIL-10 gene transfer using retroviral vectors ameliorates particle-associated inflammation in the murine air pouch model. Inflamm Res. 2002 Jul; 51(7):342-50.
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  101. Samuel RE, Lee CR, Ghivizzani SC, Evans CH, Yannas IV, Olsen BR, Spector M. Delivery of plasmid DNA to articular chondrocytes via novel collagen-glycosaminoglycan matrices. Hum Gene Ther. 2002 May 1; 13(7):791-802.
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  102. Gouze E, Pawliuk R, Pilapil C, Gouze JN, Fleet C, Palmer GD, Evans CH, Leboulch P, Ghivizzani SC. In vivo gene delivery to synovium by lentiviral vectors. Mol Ther. 2002 Apr; 5(4):397-404.
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  103. Mezey G, Evans C, Hobdell K. Families of homicide victims: psychiatric responses and help-seeking. Psychol Psychother. 2002 Mar; 75(Pt 1):65-75.
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  104. Evans C. Glimpses of autoimmunity. Trends Immunol. 2002 Feb 1; 23(2):110-111.
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  105. Palmer G, Pascher A, Gouze E, Gouze JN, Betz O, Spector M, Robbins PD, Evans CH, Ghivizzani SC. Development of gene-based therapies for cartilage repair. Crit Rev Eukaryot Gene Expr. 2002; 12(4):259-73.
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  106. Frisbie DD, Ghivizzani SC, Robbins PD, Evans CH, McIlwraith CW. Treatment of experimental equine osteoarthritis by in vivo delivery of the equine interleukin-1 receptor antagonist gene. Gene Ther. 2002 Jan; 9(1):12-20.
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  107. Sud S, Yang SY, Evans CH, Robbins PD, Wooley PH. Effects of cytokine gene therapy on particulate-induced inflammation in the murine air pouch. Inflammation. 2001 Dec; 25(6):361-72.
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  108. Whalen JD, Thomson AW, Lu L, Robbins PD, Evans CH. Viral IL-10 gene transfer inhibits DTH responses to soluble antigens: evidence for involvement of genetically modified dendritic cells and macrophages. Mol Ther. 2001 Dec; 4(6):543-50.
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  109. Baltzer AW, Whalen JD, Wooley P, Latterman C, Truchan LM, Robbins PD, Evans CH. Gene therapy for osteoporosis: evaluation in a murine ovariectomy model. Gene Ther. 2001 Dec; 8(23):1770-6.
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  110. Gouze JN, Ghivizzani SC, Gouze E, Palmer GD, Betz OB, Robbins PD, Evans CH, Herndon JH. Gene therapy for rheumatoid arthritis. Hand Surg. 2001 Dec; 6(2):211-9.
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  111. Gouze E, Ghivizzani SC, Palmer GD, Gouze JN, Robbins PD, Evans CH. Gene therapy for rheumatoid arthritis. Expert Opin Biol Ther. 2001 Nov; 1(6):971-8.
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  112. Saxer RA, Bent SJ, Brower-Toland BD, Mi Z, Robbins PD, Evans CH, Nixon AJ. Gene mediated insulin-like growth factor-I delivery to the synovium. J Orthop Res. 2001 Sep; 19(5):759-67.
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  113. Yao Q, Wang S, Glorioso JC, Evans CH, Robbins PD, Ghivizzani SC, Oligino TJ. Gene transfer of p53 to arthritic joints stimulates synovial apoptosis and inhibits inflammation. Mol Ther. 2001 Jun; 3(6):901-10.
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  114. Del Vecchio MA, Georgescu HI, McCormack JE, Robbins PD, Evans CH. Approaches to enhancing the retroviral transduction of human synoviocytes. Arthritis Res. 2001; 3(4):259-63.
    View in: PubMed
  115. Kim SH, Kim S, Evans CH, Ghivizzani SC, Oligino T, Robbins PD. Effective treatment of established murine collagen-induced arthritis by systemic administration of dendritic cells genetically modified to express IL-4. J Immunol. 2001 Mar 1; 166(5):3499-505.
    View in: PubMed
  116. Evans CH, Ghivizzani SC, Oligino TA, Robbins PD. Future of adenoviruses in the gene therapy of arthritis. Arthritis Res. 2001; 3(3):142-6.
    View in: PubMed
  117. Gouze E, Ghivizzani SC, Robbins PD, Evans CH. Gene therapy for rheumatoid arthritis. Curr Rheumatol Rep. 2001 Feb; 3(1):79-85.
    View in: PubMed
  118. Brower-Toland BD, Saxer RA, Goodrich LR, Mi Z, Robbins PD, Evans CH, Nixon AJ. Direct adenovirus-mediated insulin-like growth factor I gene transfer enhances transplant chondrocyte function. Hum Gene Ther. 2001 Jan 20; 12(2):117-29.
    View in: PubMed
  119. Mi Z, Ghivizzani SC, Lechman ER, Jaffurs D, Glorioso JC, Evans CH, Robbins PD. Adenovirus-mediated gene transfer of insulin-like growth factor 1 stimulates proteoglycan synthesis in rabbit joints. Arthritis Rheum. 2000 Nov; 43(11):2563-70.
    View in: PubMed
  120. Moon SH, Gilbertson LG, Nishida K, Knaub M, Muzzonigro T, Robbins PD, Evans CH, Kang JD. Human intervertebral disc cells are genetically modifiable by adenovirus-mediated gene transfer: implications for the clinical management of intervertebral disc disorders. Spine (Phila Pa 1976). 2000 Oct 15; 25(20):2573-9.
    View in: PubMed
  121. Evans CH, Ghivizzani SC, Herndon JH, Wasko MC, Reinecke J, Wehling P, Robbins PD. Clinical trials in the gene therapy of arthritis. Clin Orthop Relat Res. 2000 Oct; (379 Suppl):S300-7.
    View in: PubMed
  122. Nixon AJ, Brower-Toland BD, Bent SJ, Saxer RA, Wilke MJ, Robbins PD, Evans CH. Insulinlike growth factor-I gene therapy applications for cartilage repair. Clin Orthop Relat Res. 2000 Oct; (379 Suppl):S201-13.
    View in: PubMed
  123. Evans CH, Ghivizzani SC, Smith P, Shuler FD, Mi Z, Robbins PD. Using gene therapy to protect and restore cartilage. Clin Orthop Relat Res. 2000 Oct; (379 Suppl):S214-9.
    View in: PubMed
  124. Baltzer AW, Lattermann C, Whalen JD, Ghivizzani S, Wooley P, Krauspe R, Robbins PD, Evans CH. Potential role of direct adenoviral gene transfer in enhancing fracture repair. Clin Orthop Relat Res. 2000 Oct; (379 Suppl):S120-5.
    View in: PubMed
  125. Gassner RJ, Buckley MJ, Studer RK, Evans CH, Agarwal S. Interaction of strain and interleukin-1 in articular cartilage: effects on proteoglycan synthesis in chondrocytes. Int J Oral Maxillofac Surg. 2000 Oct; 29(5):389-94.
    View in: PubMed
  126. Studer RK, Levicoff E, Georgescu H, Miller L, Jaffurs D, Evans CH. Nitric oxide inhibits chondrocyte response to IGF-I: inhibition of IGF-IRbeta tyrosine phosphorylation. Am J Physiol Cell Physiol. 2000 Oct; 279(4):C961-9.
    View in: PubMed
  127. Ghivizzani SC, Evans CH. Gene therapy for rheumatoid arthritis. Clin Orthop Relat Res. 2000 Oct; (379 Suppl):S308-10.
    View in: PubMed
  128. Ghivizzani SC, Oligino TJ, Glorioso JC, Robbins PD, Evans CH. Gene therapy approaches for treating rheumatoid arthritis. Clin Orthop Relat Res. 2000 Oct; (379 Suppl):S288-99.
    View in: PubMed
  129. Nishida K, Gilbertson LG, Robbins PD, Evans CH, Kang JD. Potential applications of gene therapy to the treatment of intervertebral disc disorders. Clin Orthop Relat Res. 2000 Oct; (379 Suppl):S234-41.
    View in: PubMed
  130. Evans CH, Ghivizzani SC, Oligino TJ, Robbins PD. Gene therapy for autoimmune disorders. J Clin Immunol. 2000 Sep; 20(5):334-46.
    View in: PubMed
  131. Xu Z, Buckley MJ, Evans CH, Agarwal S. Cyclic tensile strain acts as an antagonist of IL-1 beta actions in chondrocytes. J Immunol. 2000 Jul 1; 165(1):453-60.
    View in: PubMed
  132. Goto H, Shuler FD, Niyibizi C, Fu FH, Robbins PD, Evans CH. Gene therapy for meniscal injury: enhanced synthesis of proteoglycan and collagen by meniscal cells transduced with a TGFbeta(1)gene. Osteoarthritis Cartilage. 2000 Jul; 8(4):266-71.
    View in: PubMed
  133. Shuler FD, Georgescu HI, Niyibizi C, Studer RK, Mi Z, Johnstone B, Robbins RD, Evans CH. Increased matrix synthesis following adenoviral transfer of a transforming growth factor beta1 gene into articular chondrocytes. J Orthop Res. 2000 Jul; 18(4):585-92.
    View in: PubMed
  134. Kang R, Ghivizzani SC, Muzzonigro TS, Herndon JH, Robbins PD, Evans CH. The Marshall R. Urist Young Investigator Award. Orthopaedic applications of gene therapy. From concept to clinic. Clin Orthop Relat Res. 2000 Jun; (375):324-37.
    View in: PubMed
  135. Kim SH, Evans CH, Kim S, Oligino T, Ghivizzani SC, Robbins PD. Gene therapy for established murine collagen-induced arthritis by local and systemic adenovirus-mediated delivery of interleukin-4. Arthritis Res. 2000; 2(4):293-302.
    View in: PubMed
  136. Nishida K, Gilbertson LG, Evans CH, Kang JD. Spine update: potential applications of gene therapy to the treatment of spinal disorders. Spine (Phila Pa 1976). 2000 May 15; 25(10):1308-14.
    View in: PubMed
  137. Yao Q, Glorioso JC, Evans CH, Robbins PD, Kovesdi I, Oligino TJ, Ghivizzani SC. Adenoviral mediated delivery of FAS ligand to arthritic joints causes extensive apoptosis in the synovial lining. J Gene Med. 2000 May-Jun; 2(3):210-9.
    View in: PubMed
  138. Smith P, Shuler FD, Georgescu HI, Ghivizzani SC, Johnstone B, Niyibizi C, Robbins PD, Evans CH. Genetic enhancement of matrix synthesis by articular chondrocytes: comparison of different growth factor genes in the presence and absence of interleukin-1. Arthritis Rheum. 2000 May; 43(5):1156-64.
    View in: PubMed
  139. Baltzer AW, Lattermann C, Whalen JD, Wooley P, Weiss K, Grimm M, Ghivizzani SC, Robbins PD, Evans CH. Genetic enhancement of fracture repair: healing of an experimental segmental defect by adenoviral transfer of the BMP-2 gene. Gene Ther. 2000 May; 7(9):734-9.
    View in: PubMed
  140. Ghivizzani SC, Oligino TJ, Robbins PD, Evans CH. Cartilage injury and repair. Phys Med Rehabil Clin N Am. 2000 May; 11(2):289-307, vi.
    View in: PubMed
  141. Evans CH, Ghivizzani SC, Robbins PD. Potential applications of gene therapy in sports medicine. Phys Med Rehabil Clin N Am. 2000 May; 11(2):405-16.
    View in: PubMed
  142. Londino AV, Rothman D, Robbins PD, Evans CH. Gene therapy for juvenile rheumatoid arthritis? J Rheumatol Suppl. 2000 Apr; 58:53-5.
    View in: PubMed
  143. Sechriest VF, Miao YJ, Niyibizi C, Westerhausen-Larson A, Matthew HW, Evans CH, Fu FH, Suh JK. GAG-augmented polysaccharide hydrogel: a novel biocompatible and biodegradable material to support chondrogenesis. J Biomed Mater Res. 2000 Mar 15; 49(4):534-41.
    View in: PubMed
  144. Möller HD, Evans CH, Maffulli N. [Current aspects of tendon healing]. Orthopade. 2000 Mar; 29(3):182-7.
    View in: PubMed
  145. Cao M, Stefanovic-Racic M, Georgescu HI, Fu FH, Evans CH. Does nitric oxide help explain the differential healing capacity of the anterior cruciate, posterior cruciate, and medial collateral ligaments? Am J Sports Med. 2000 Mar-Apr; 28(2):176-82.
    View in: PubMed
  146. Möller HD, Fu FH, Niyibizi C, Studer RK, Georgescu HJ, Robbins PD, Evans CH. [TGF-beta-1 gene transfer in joint cartilage cells. Stimulating effect in extracellular matrix synthesis]. Orthopade. 2000 Feb; 29(2):75-9.
    View in: PubMed
  147. Evans CH, Robbins PD. Gene therapy in orthopaedics. Orthop Nurs. 2000 Jan-Feb; 19(1):16-22.
    View in: PubMed
  148. Nishida K, Kang JD, Gilbertson LG, Moon SH, Suh JK, Vogt MT, Robbins PD, Evans CH. Modulation of the biologic activity of the rabbit intervertebral disc by gene therapy: an in vivo study of adenovirus-mediated transfer of the human transforming growth factor beta 1 encoding gene. Spine (Phila Pa 1976). 1999 Dec 1; 24(23):2419-25.
    View in: PubMed
  149. Weiss KR, Georgescu HI, Gollin SM, Kang R, Evans CH. Trisomy 7 in synovial fibroblasts obtained from arthritic joints. Inflamm Res. 1999 Dec; 48 Suppl 2:S132-3.
    View in: PubMed
  150. Evans CH, Robbins PD. Genetically augmented tissue engineering of the musculoskeletal system. Clin Orthop Relat Res. 1999 Oct; (367 Suppl):S410-8.
    View in: PubMed
  151. Baltzer AW, Whalen JD, Stefanovic-Racic M, Ziran B, Robbins PD, Evans CH. Adenoviral transduction of human osteoblastic cell cultures: a new perspective for gene therapy of bone diseases. Acta Orthop Scand. 1999 Oct; 70(5):419-24.
    View in: PubMed
  152. Lechman ER, Jaffurs D, Ghivizzani SC, Gambotto A, Kovesdi I, Mi Z, Evans CH, Robbins PD. Direct adenoviral gene transfer of viral IL-10 to rabbit knees with experimental arthritis ameliorates disease in both injected and contralateral control knees. J Immunol. 1999 Aug 15; 163(4):2202-8.
    View in: PubMed
  153. Gassner R, Buckley MJ, Georgescu H, Studer R, Stefanovich-Racic M, Piesco NP, Evans CH, Agarwal S. Cyclic tensile stress exerts antiinflammatory actions on chondrocytes by inhibiting inducible nitric oxide synthase. J Immunol. 1999 Aug 15; 163(4):2187-92.
    View in: PubMed
  154. Evans CH. Cytokines and the role they play in the healing of ligaments and tendons. Sports Med. 1999 Aug; 28(2):71-6.
    View in: PubMed
  155. Evans CH, Ghivizzani SC, Lechman ER, Mi Z, Jaffurs D, Robbins PD. Lessons learned from gene transfer approaches. Arthritis Res. 1999; 1(1):21-4.
    View in: PubMed
  156. Goto H, Shuler FD, Lamsam C, Moller HD, Niyibizi C, Fu FH, Robbins PD, Evans CH. Transfer of lacZ marker gene to the meniscus. J Bone Joint Surg Am. 1999 Jul; 81(7):918-25.
    View in: PubMed
  157. Studer R, Jaffurs D, Stefanovic-Racic M, Robbins PD, Evans CH. Nitric oxide in osteoarthritis. Osteoarthritis Cartilage. 1999 Jul; 7(4):377-9.
    View in: PubMed
  158. Musgrave DS, Bosch P, Ghivizzani S, Robbins PD, Evans CH, Huard J. Adenovirus-mediated direct gene therapy with bone morphogenetic protein-2 produces bone. Bone. 1999 Jun; 24(6):541-7.
    View in: PubMed
  159. Evans CH, Robbins PD. Potential treatment of osteoarthritis by gene therapy. Rheum Dis Clin North Am. 1999 May; 25(2):333-44.
    View in: PubMed
  160. Baltzer AW, Whalen JD, Muzzonegro T, Georgescu HI, Robbins PD, Evans CH. [In vitro transduction of human osteoblast cell populations with retroviral vectors]. Z Rheumatol. 1999 Apr; 58(2):88-94.
    View in: PubMed
  161. Ghivizzani SC, Muzzonigro TS, Kang R, Evans CH, Robbins PD. Clinical gene therapy for arthritis. Drugs Today (Barc). 1999 Apr-May; 35(4-5):389-96.
    View in: PubMed
  162. Evans CH, Rediske JJ, Abramson SB, Robbins PD. Joint efforts: tackling arthritis using gene therapy. First International Meeting on the Gene Therapy of Arthritis and Related Disorders. Bethesda, MD, USA, 2-3 December 1998. Mol Med Today. 1999 Apr; 5(4):148-51.
    View in: PubMed
  163. Robbins PD, Evans CH. Arthritis gene therapy. Drugs Today (Barc). 1999 Apr-May; 35(4-5):353-60.
    View in: PubMed
  164. Whalen JD, Lechman EL, Carlos CA, Weiss K, Kovesdi I, Glorioso JC, Robbins PD, Evans CH. Adenoviral transfer of the viral IL-10 gene periarticularly to mouse paws suppresses development of collagen-induced arthritis in both injected and uninjected paws. J Immunol. 1999 Mar 15; 162(6):3625-32.
    View in: PubMed
  165. Oyama M, Tatlock A, Fukuta S, Kavalkovich K, Nishimura K, Johnstone B, Robbins PD, Evans CH, Niyibizi C. Retrovirally transduced bone marrow stromal cells isolated from a mouse model of human osteogenesis imperfecta (oim) persist in bone and retain the ability to form cartilage and bone after extended passaging. Gene Ther. 1999 Mar; 6(3):321-9.
    View in: PubMed
  166. Müller-Ladner U, Evans CH, Franklin BN, Roberts CR, Gay RE, Robbins PD, Gay S. Gene transfer of cytokine inhibitors into human synovial fibroblasts in the SCID mouse model. Arthritis Rheum. 1999 Mar; 42(3):490-7.
    View in: PubMed
  167. Evans CH, Robbins PD. Gene therapy of arthritis. Intern Med. 1999 Mar; 38(3):233-9.
    View in: PubMed
  168. Studer RK, Georgescu HI, Miller LA, Evans CH. Inhibition of transforming growth factor beta production by nitric oxide-treated chondrocytes: implications for matrix synthesis. Arthritis Rheum. 1999 Feb; 42(2):248-57.
    View in: PubMed
  169. Herndon JH, Robbins PD, Evans CH. Arthritis: is the cure in your genes? J Bone Joint Surg Am. 1999 Feb; 81(2):152-7.
    View in: PubMed
  170. Möller HD, Evans CH. [Gene transfer in the treatment of arthritis]. Orthopade. 1999 Jan; 28(1):76-81.
    View in: PubMed
  171. Evans CH, Ghivizzani SC, Kang R, Muzzonigro T, Wasko MC, Herndon JH, Robbins PD. Gene therapy for rheumatic diseases. Arthritis Rheum. 1999 Jan; 42(1):1-16.
    View in: PubMed
  172. Hildebrand KA, Deie M, Allen CR, Smith DW, Georgescu HI, Evans CH, Robbins PD, Woo SL. Early expression of marker genes in the rabbit medial collateral and anterior cruciate ligaments: the use of different viral vectors and the effects of injury. J Orthop Res. 1999 Jan; 17(1):37-42.
    View in: PubMed
  173. Suh JK, Baek GH, Arøen A, Malin CM, Niyibizi C, Evans CH, Westerhausen-Larson A. Intermittent sub-ambient interstitial hydrostatic pressure as a potential mechanical stimulator for chondrocyte metabolism. Osteoarthritis Cartilage. 1999 Jan; 7(1):71-80.
    View in: PubMed
  174. Muzzonigro TS, Ghivizzani SC, Robbins PD, Evans CH. The role of gene therapy. Fact or fiction? Clin Sports Med. 1999 Jan; 18(1):223-39, vii-viii.
    View in: PubMed
  175. Baltzer AW, Lattermann C, Whalen JD, Braunstein S, Robbins PD, Evans CH. A gene therapy approach to accelerating bone healing. Evaluation of gene expression in a New Zealand white rabbit model. Knee Surg Sports Traumatol Arthrosc. 1999; 7(3):197-202.
    View in: PubMed
  176. Nishida K, Kang JD, Suh JK, Robbins PD, Evans CH, Gilbertson LG. Adenovirus-mediated gene transfer to nucleus pulposus cells. Implications for the treatment of intervertebral disc degeneration. Spine (Phila Pa 1976). 1998 Nov 15; 23(22):2437-42; discussion 2443.
    View in: PubMed
  177. Whalen JD, Robbins PD, Evans CH. Gene therapy in arthritis. IDrugs. 1998 Nov; 1(7):802-6.
    View in: PubMed
  178. Niyibizi C, Baltzer A, Lattermann C, Oyama M, Whalen JD, Robbins PD, Evans CH. Potential role for gene therapy in the enhancement of fracture healing. Clin Orthop Relat Res. 1998 Oct; (355 Suppl):S148-53.
    View in: PubMed
  179. Evans CH, Ghivizzani SC, Robbins PD. Blocking cytokines with genes. J Leukoc Biol. 1998 Jul; 64(1):55-61.
    View in: PubMed
  180. Ghivizzani SC, Lechman ER, Kang R, Tio C, Kolls J, Evans CH, Robbins PD. Direct adenovirus-mediated gene transfer of interleukin 1 and tumor necrosis factor alpha soluble receptors to rabbit knees with experimental arthritis has local and distal anti-arthritic effects. Proc Natl Acad Sci U S A. 1998 Apr 14; 95(8):4613-8.
    View in: PubMed
  181. Evans CH, Whalen JD, Evans CH, Ghivizzani SC, Robbins PD. Gene therapy in autoimmune diseases. Ann Rheum Dis. 1998 Mar; 57(3):125-7.
    View in: PubMed
  182. Lamsam C, Fu FH, Robbins PD, Evans CH. Gene therapy in sports medicine. Sports Med. 1998 Feb; 25(2):73-7.
    View in: PubMed
  183. Häuselmann HJ, Stefanovic-Racic M, Michel BA, Evans CH. Differences in nitric oxide production by superficial and deep human articular chondrocytes: implications for proteoglycan turnover in inflammatory joint diseases. J Immunol. 1998 Feb 1; 160(3):1444-8.
    View in: PubMed
  184. Cao M, Stefanovic-Racic M, Georgescu HI, Miller LA, Evans CH. Generation of nitric oxide by lapine meniscal cells and its effect on matrix metabolism: stimulation of collagen production by arginine. J Orthop Res. 1998 Jan; 16(1):104-11.
    View in: PubMed
  185. Robbins PD, Evans CH, Chernajovsky Y. Gene therapy for rheumatoid arthritis. Springer Semin Immunopathol. 1998; 20(1-2):197-209.
    View in: PubMed
  186. Jaffurs D, Evans CH. The Human Genome Project: implications for the treatment of musculoskeletal disease. J Am Acad Orthop Surg. 1998 Jan-Feb; 6(1):1-14.
    View in: PubMed
  187. Evans CH, Robbins PD. Getting genes into human synovium. J Rheumatol. 1997 Nov; 24(11):2061-3.
    View in: PubMed
  188. Cameron M, Buchgraber A, Passler H, Vogt M, Thonar E, Fu F, Evans CH. The natural history of the anterior cruciate ligament-deficient knee. Changes in synovial fluid cytokine and keratan sulfate concentrations. Am J Sports Med. 1997 Nov-Dec; 25(6):751-4.
    View in: PubMed
  189. Ghivizzani SC, Kang R, Georgescu HI, Lechman ER, Jaffurs D, Engle JM, Watkins SC, Tindal MH, Suchanek MK, McKenzie LR, Evans CH, Robbins PD. Constitutive intra-articular expression of human IL-1 beta following gene transfer to rabbit synovium produces all major pathologies of human rheumatoid arthritis. J Immunol. 1997 Oct 1; 159(7):3604-12.
    View in: PubMed
  190. Ghivizzani SC, Lechman ER, Tio C, Mulé KM, Chada S, McCormack JE, Evans CH, Robbins PD. Direct retrovirus-mediated gene transfer to the synovium of the rabbit knee: implications for arthritis gene therapy. Gene Ther. 1997 Sep; 4(9):977-82.
    View in: PubMed
  191. Reinecke JA, Wehling P, Robbins P, Evans CH, Sager M, Schulze-Allen G, Koch H. [In vitro transfer of genes in spinal tissue]. Z Orthop Ihre Grenzgeb. 1997 Sep-Oct; 135(5):412-6.
    View in: PubMed
  192. Engle JM, Georgescu HI, Evans CH. Interleukin-1 alpha as an autocrine regulator in rabbit synovial fibroblasts. Inflamm Res. 1997 Aug; 46 Suppl 2:S175-6.
    View in: PubMed
  193. Evans CH, Robbins PD. Gene therapy for arthritis. Expert Opin Investig Drugs. 1997 Jul; 6(7):837-40.
    View in: PubMed
  194. Balk ML, Bray J, Day C, Epperly M, Greenberger J, Evans CH, Niyibizi C. Effect of rhBMP-2 on the osteogenic potential of bone marrow stromal cells from an osteogenesis imperfecta mouse (oim). Bone. 1997 Jul; 21(1):7-15.
    View in: PubMed
  195. Gerich TG, Ghivizani S, Fu FH, Robbins PD, Evans CH. [Gene transfer into the patellar tendon of rabbits: a preliminary study of locoregional expression of growth factors]. Wien Klin Wochenschr. 1997 Jun 6; 109(11):384-9.
    View in: PubMed
  196. Cao M, Westerhausen-Larson A, Niyibizi C, Kavalkovich K, Georgescu HI, Rizzo CF, Hebda PA, Stefanovic-Racic M, Evans CH. Nitric oxide inhibits the synthesis of type-II collagen without altering Col2A1 mRNA abundance: prolyl hydroxylase as a possible target. Biochem J. 1997 May 15; 324 ( Pt 1):305-10.
    View in: PubMed
  197. Wehling P, Schulitz KP, Robbins PD, Evans CH, Reinecke JA. Transfer of genes to chondrocytic cells of the lumbar spine. Proposal for a treatment strategy of spinal disorders by local gene therapy. Spine (Phila Pa 1976). 1997 May 15; 22(10):1092-7.
    View in: PubMed
  198. Kang JD, Stefanovic-Racic M, McIntyre LA, Georgescu HI, Evans CH. Toward a biochemical understanding of human intervertebral disc degeneration and herniation. Contributions of nitric oxide, interleukins, prostaglandin E2, and matrix metalloproteinases. Spine (Phila Pa 1976). 1997 May 15; 22(10):1065-73.
    View in: PubMed
  199. Gerich TG, Lobenhoffer P, Fu FH, Robbins PD, Evans CH. [Possibilities of gene therapy in traumatic and degenerative articular lesions. Current status of experimental and initial clinical applications]. Orthopade. 1997 May; 26(5):450-8.
    View in: PubMed
  200. Stefanovic-Racic M, Möllers MO, Miller LA, Evans CH. Nitric oxide and proteoglycan turnover in rabbit articular cartilage. J Orthop Res. 1997 May; 15(3):442-9.
    View in: PubMed
  201. Gerich TG, Lobenhoffer HP, Fu FH, Robbins PD, Evans CH. [Virally mediated gene transfer in the patellar tendon. An experimental study in rabbits]. Unfallchirurg. 1997 May; 100(5):354-62.
    View in: PubMed
  202. Kang R, Ghivizzani SC, Herndon JH, Robbins PD, Evans CH. Gene therapy for arthritis: principles and clinical practice. Biochem Soc Trans. 1997 May; 25(2):533-7.
    View in: PubMed
  203. Watkins SC, Macaulay W, Turner D, Kang R, Rubash HE, Evans CH. Identification of inducible nitric oxide synthase in human macrophages surrounding loosened hip prostheses. Am J Pathol. 1997 Apr; 150(4):1199-206.
    View in: PubMed
  204. Müller-Ladner U, Roberts CR, Franklin BN, Gay RE, Robbins PD, Evans CH, Gay S. Human IL-1Ra gene transfer into human synovial fibroblasts is chondroprotective. J Immunol. 1997 Apr 1; 158(7):3492-8.
    View in: PubMed
  205. Kang R, Marui T, Ghivizzani SC, Nita IM, Georgescu HI, Suh JK, Robbins PD, Evans CH. Ex vivo gene transfer to chondrocytes in full-thickness articular cartilage defects: a feasibility study. Osteoarthritis Cartilage. 1997 Mar; 5(2):139-43.
    View in: PubMed
  206. Doughty LA, Patrene KD, Evans CH, Boggs SS, Robbins PD. Constitutive systemic expression of IL-1Ra or soluble TNF receptor by genetically modified hematopoietic cells suppresses LPS induction of IL-6 and IL-10. Gene Ther. 1997 Mar; 4(3):252-7.
    View in: PubMed
  207. Gerich TG, Kang R, Fu FH, Robbins PD, Evans CH. Gene transfer to the patellar tendon. Knee Surg Sports Traumatol Arthrosc. 1997; 5(2):118-23.
    View in: PubMed
  208. Scherping SC, Schmidt CC, Georgescu HI, Kwoh CK, Evans CH, Woo SL. Effect of growth factors on the proliferation of ligament fibroblasts from skeletally mature rabbits. Connect Tissue Res. 1997; 36(1):1-8.
    View in: PubMed
  209. Gerich TG, Kang R, Fu FH, Robbins PD, Evans CH. Gene transfer to the rabbit patellar tendon: potential for genetic enhancement of tendon and ligament healing. Gene Ther. 1996 Dec; 3(12):1089-93.
    View in: PubMed
  210. Evans CH, Robbins PD, Ghivizzani SC, Herndon JH, Kang R, Bahnson AB, Barranger JA, Elders EM, Gay S, Tomaino MM, Wasko MC, Watkins SC, Whiteside TL, Glorioso JC, Lotze MT, Wright TM. Clinical trial to assess the safety, feasibility, and efficacy of transferring a potentially anti-arthritic cytokine gene to human joints with rheumatoid arthritis. Hum Gene Ther. 1996 Jun 20; 7(10):1261-80.
    View in: PubMed
  211. Otani K, Nita I, Macaulay W, Georgescu HI, Robbins PD, Evans CH. Suppression of antigen-induced arthritis in rabbits by ex vivo gene therapy. J Immunol. 1996 May 1; 156(9):3558-62.
    View in: PubMed
  212. Nita I, Ghivizzani SC, Galea-Lauri J, Bandara G, Georgescu HI, Robbins PD, Evans CH. Direct gene delivery to synovium. An evaluation of potential vectors in vitro and in vivo. Arthritis Rheum. 1996 May; 39(5):820-8.
    View in: PubMed
  213. Evans CH, Robbins PD. Pathways to gene therapy in rheumatoid arthritis. Curr Opin Rheumatol. 1996 May; 8(3):230-4.
    View in: PubMed
  214. Wehling P, Cleveland SJ, Heininger K, Schulitz KP, Reinecke J, Evans CH. Neurophysiologic changes in lumbar nerve root inflammation in the rat after treatment with cytokine inhibitors. Evidence for a role of interleukin-1. Spine (Phila Pa 1976). 1996 Apr 15; 21(8):931-5.
    View in: PubMed
  215. Robbins PD, Evans CH. Prospects for treating autoimmune and inflammatory diseases by gene therapy. Gene Ther. 1996 Mar; 3(3):187-9.
    View in: PubMed
  216. Lin CW, Robbins PD, Georgescu HI, Evans CH. Effects of immortalization upon the induction of matrix metalloproteinases in rabbit synovial fibroblasts. Exp Cell Res. 1996 Feb 25; 223(1):117-26.
    View in: PubMed
  217. Kang JD, Georgescu HI, McIntyre-Larkin L, Stefanovic-Racic M, Donaldson WF, Evans CH. Herniated lumbar intervertebral discs spontaneously produce matrix metalloproteinases, nitric oxide, interleukin-6, and prostaglandin E2. Spine (Phila Pa 1976). 1996 Feb 1; 21(3):271-7.
    View in: PubMed
  218. Stefanovic-Racic M, Morales TI, Taskiran D, McIntyre LA, Evans CH. The role of nitric oxide in proteoglycan turnover by bovine articular cartilage organ cultures. J Immunol. 1996 Feb 1; 156(3):1213-20.
    View in: PubMed
  219. DeKosky ST, Styren SD, O'Malley ME, Goss JR, Kochanek P, Marion D, Evans CH, Robbins PD. Interleukin-1 receptor antagonist suppresses neurotrophin response in injured rat brain. Ann Neurol. 1996 Jan; 39(1):123-7.
    View in: PubMed
  220. Evans CH, Watkins SC, Stefanovic-Racic M. Nitric oxide and cartilage metabolism. Methods Enzymol. 1996; 269:75-88.
    View in: PubMed
  221. Gerich TG, Fu FH, Robbins PD, Evans CH. Prospects for gene therapy in sports medicine. Knee Surg Sports Traumatol Arthrosc. 1996; 4(3):180-7.
    View in: PubMed
  222. Evans CH, Robbins PD. The promise of a new clinical trial--intra-articular IL-1 receptor antagonist. Proc Assoc Am Physicians. 1996 Jan; 108(1):1-5.
    View in: PubMed
  223. Kang JD, Georgescu HI, McIntyre-Larkin L, Stefanovic-Racic M, Evans CH. Herniated cervical intervertebral discs spontaneously produce matrix metalloproteinases, nitric oxide, interleukin-6, and prostaglandin E2. Spine (Phila Pa 1976). 1995 Nov 15; 20(22):2373-8.
    View in: PubMed
  224. Boggs SS, Patrene KD, Mueller GM, Evans CH, Doughty LA, Robbins PD. Prolonged systemic expression of human IL-1 receptor antagonist (hIL-1ra) in mice reconstituted with hematopoietic cells transduced with a retrovirus carrying the hIL-1ra cDNA. Gene Ther. 1995 Nov; 2(9):632-8.
    View in: PubMed
  225. Evans CH, Robbins PD. Progress toward the treatment of arthritis by gene therapy. Ann Med. 1995 Oct; 27(5):543-6.
    View in: PubMed
  226. Stefanovic-Racic M, Meyers K, Meschter C, Coffey JW, Hoffman RA, Evans CH. Comparison of the nitric oxide synthase inhibitors methylarginine and aminoguanidine as prophylactic and therapeutic agents in rat adjuvant arthritis. J Rheumatol. 1995 Oct; 22(10):1922-8.
    View in: PubMed
  227. Stefanovic-Racic M, Taskiran D, Georgescu HI, Evans CH. Modulation of chondrocyte proteoglycan synthesis by endogeneously produced nitric oxide. Inflamm Res. 1995 Aug; 44 Suppl 2:S216-7.
    View in: PubMed
  228. Evans CH, Robbins PD. Possible orthopaedic applications of gene therapy. J Bone Joint Surg Am. 1995 Jul; 77(7):1103-14.
    View in: PubMed
  229. Evans CH, Stefanovic-Racic M, Lancaster J. Nitric oxide and its role in orthopaedic disease. Clin Orthop Relat Res. 1995 Mar; (312):275-94.
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  230. Schmidt CC, Georgescu HI, Kwoh CK, Blomstrom GL, Engle CP, Larkin LA, Evans CH, Woo SL. Effect of growth factors on the proliferation of fibroblasts from the medial collateral and anterior cruciate ligaments. J Orthop Res. 1995 Mar; 13(2):184-90.
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  231. Evans CH, Robbins PD. Arthritis. Mol Cell Biol Hum Dis Ser. 1995; 5:252-60.
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  232. Evans CH. Faculty development in a changing academic environment. Acad Med. 1995 Jan; 70(1):14-20.
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  233. Evans CH. Nitric oxide: what role does it play in inflammation and tissue destruction? Agents Actions Suppl. 1995; 47:107-16.
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  234. Evans CH, Wehling P, Reinecke J. [Perspectives in gene therapy in rheumatic and degenerative diseases of the spine and joints]. Z Orthop Ihre Grenzgeb. 1994 Nov-Dec; 132(6):449-52.
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  235. Stefanovic-Racic M, Stadler J, Georgescu HI, Evans CH. Nitric oxide synthesis and its regulation by rabbit synoviocytes. J Rheumatol. 1994 Oct; 21(10):1892-8.
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  236. Stefanovic-Racic M, Meyers K, Meschter C, Coffey JW, Hoffman RA, Evans CH. N-monomethyl arginine, an inhibitor of nitric oxide synthase, suppresses the development of adjuvant arthritis in rats. Arthritis Rheum. 1994 Jul; 37(7):1062-9.
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  237. Stefanovic-Racic M, Stadler J, Georgescu HI, Evans CH. Nitric oxide and energy production in articular chondrocytes. J Cell Physiol. 1994 May; 159(2):274-80.
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  238. Greis PE, Georgescu HI, Fu FH, Evans CH. Particle-induced synthesis of collagenase by synovial fibroblasts: an immunocytochemical study. J Orthop Res. 1994 Mar; 12(2):286-93.
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  239. Cameron ML, Fu FH, Paessler HH, Schneider M, Evans CH. Synovial fluid cytokine concentrations as possible prognostic indicators in the ACL-deficient knee. Knee Surg Sports Traumatol Arthrosc. 1994; 2(1):38-44.
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  240. Evans CH, Robbins PD. The interleukin-1 receptor antagonist and its delivery by gene transfer. Receptor. 1994; 4(1):9-15.
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  241. Hung GL, Galea-Lauri J, Mueller GM, Georgescu HI, Larkin LA, Suchanek MK, Tindal MH, Robbins PD, Evans CH. Suppression of intra-articular responses to interleukin-1 by transfer of the interleukin-1 receptor antagonist gene to synovium. Gene Ther. 1994 Jan; 1(1):64-9.
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  242. Bandara G, Mueller GM, Galea-Lauri J, Tindal MH, Georgescu HI, Suchanek MK, Hung GL, Glorioso JC, Robbins PD, Evans CH. Intraarticular expression of biologically active interleukin 1-receptor-antagonist protein by ex vivo gene transfer. Proc Natl Acad Sci U S A. 1993 Nov 15; 90(22):10764-8.
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  243. Stefanovic-Racic M, Stadler J, Evans CH. Nitric oxide and arthritis. Arthritis Rheum. 1993 Aug; 36(8):1036-44.
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  244. Silvaggio VJ, Fu FH, Georgescu HI, Evans CH. The induction of IL-1 by freeze-dried ethylene oxide-treated bone-patellar tendon-bone allograft wear particles: an in vitro study. Arthroscopy. 1993; 9(1):82-6.
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  245. Lin CW, Georgescu HI, Evans CH. The role of AP-1 in matrix metalloproteinase gene expression. Agents Actions. 1993; 39 Spec No:C215-8.
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  246. Wehling P, Wirths J, Evans CH. [The effect of cytokines on regeneration results of compressed nerve roots and transsected peripheral nerves]. Z Orthop Ihre Grenzgeb. 1993 Jan-Feb; 131(1):83-93.
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  247. Evans CH, Bandara G, Mueller G, Robbins P, Glorioso JC, Georgescu HI. Synovial cell transplants for gene transfer to joints. Transplant Proc. 1992 Dec; 24(6):2966.
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  248. Hulkower KI, Sagi-Eisenberg R, Traub LM, Georgescu HI, Evans CH. Synovial protein kinase C and its apparent insensitivity to interleukin-1. Eur J Biochem. 1992 Oct 1; 209(1):81-8.
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  249. Mauviel A, Evans CH, Uitto J. Leukoregulin down-regulates type I collagen mRNA levels and promoter activity in human dermal fibroblasts, and counteracts the up-regulation elicited by transforming growth factor-beta. Biochem J. 1992 Jun 15; 284 ( Pt 3):629-32.
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  250. Bandara G, Lin CW, Georgescu HI, Evans CH. The synovial activation of chondrocytes: evidence for complex cytokine interactions involving a possible novel factor. Biochim Biophys Acta. 1992 Apr 7; 1134(3):309-18.
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  251. Bandara G, Robbins PD, Georgescu HI, Mueller GM, Glorioso JC, Evans CH. Gene transfer to synoviocytes: prospects for gene treatment of arthritis. DNA Cell Biol. 1992 Apr; 11(3):227-31.
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  252. Stadler J, Stefanovic-Racic M, Billiar TR, Curran RD, McIntyre LA, Georgescu HI, Simmons RL, Evans CH. Articular chondrocytes synthesize nitric oxide in response to cytokines and lipopolysaccharide. J Immunol. 1991 Dec 1; 147(11):3915-20.
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  253. Evans CH, Georgescu HI, Lin CW, Mendelow D, Steed DL, Webster MW. Inducible synthesis of collagenase and other neutral metalloproteinases by cells of aortic origin. J Surg Res. 1991 Nov; 51(5):399-404.
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  254. Baratz ME, Georgescu HI, Evans CH. Studies on the autocrine activation of a synovial cell line. J Orthop Res. 1991 Sep; 9(5):651-7.
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  255. Hulkower KI, Sagi-Eisenberg R, Traub LM, Georgescu HI, Evans CH. Interleukin-1 and synovial protein kinase C: identification of a novel, 35 kDa cytosolic substrate. Agents Actions. 1991 Sep; 34(1-2):278-81.
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  256. Bandara G, Georgescu HI, Lin CW, Evans CH. Synovial activation of chondrocytes: evidence for complex cytokine interactions. Agents Actions. 1991 Sep; 34(1-2):285-8.
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  257. Webster MW, McAuley CE, Steed DL, Miller DD, Evans CH. Collagen stability and collagenolytic activity in the normal and aneurysmal human abdominal aorta. Am J Surg. 1991 Jun; 161(6):635-8.
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  258. Hulkower KI, Georgescu HI, Evans CH. Evidence that responses of articular chondrocytes to interleukin-1 and basic fibroblast growth factor are not mediated by protein kinase C. Biochem J. 1991 May 15; 276 ( Pt 1):157-62.
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  259. Hulkower KI, Evans CH. Protein phosphorylation and metalloproteinase synthesis by lapine articular chondrocytes. J Rheumatol Suppl. 1991 Feb; 27:110-3.
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  260. Wehling P, Evans CH, Schulitz KP. [The interaction between synovial cytokines and peripheral nerve function: a potential element in the development of radicular syndrome]. Z Orthop Ihre Grenzgeb. 1990 Sep-Oct; 128(5):442-6.
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  261. Hulkower KI, Georgscu HI, Evans CH. Altered patterns of protein phosphorylation in articular chondrocytes treated with interleukin-1 or synovial cytokines. FEBS Lett. 1989 Nov 6; 257(2):228-32.
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  262. Bandara G, Lin CW, Georgescu HI, Mendelow D, Evans CH. Chondrocyte activation by interleukin-1: analysis of the synergistic properties of fibroblast growth factor and phorbol myristate acetate. Arch Biochem Biophys. 1989 Nov 1; 274(2):539-47.
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  263. Hulkower KI, Georgescu HI, Evans CH. Protein kinase C and chondrocyte activation. Agents Actions. 1989 Jun; 27(3-4):442-4.
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  264. Lin CW, Georgescu HI, Phillips SL, Evans CH. Cycloheximide inhibits the induction of collagenase mRNA in chondrocytes exposed to synovial factors or recombinant interleukin-1. Agents Actions. 1989 Jun; 27(3-4):445-7.
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  265. Bandara G, Lin CW, Georgescu HI, Mendelow D, Evans CH. Chondrocyte activation by interleukin-1: synergism with fibroblast growth factor and phorbol myristate acetate. Agents Actions. 1989 Jun; 27(3-4):439-41.
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  266. Watanabe S, Georgescu HI, Kuhns DB, Evans CH. Chondrocyte activation by a putative interleukin-1 derived from lapine polymorphonuclear leukocytes. Arch Biochem Biophys. 1989 Apr; 270(1):69-76.
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  267. Olson EJ, Kang JD, Fu FH, Georgescu HI, Mason GC, Evans CH. The biochemical and histological effects of artificial ligament wear particles: in vitro and in vivo studies. Am J Sports Med. 1988 Nov-Dec; 16(6):558-70.
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  268. Georgescu HI, Mendelow D, Evans CH. HIG-82: an established cell line from rabbit periarticular soft tissue, which retains the "activatable" phenotype. In Vitro Cell Dev Biol. 1988 Oct; 24(10):1015-22.
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  269. Sung K, Mendelow D, Georgescu HI, Evans CH. Characterisation of chondrocyte activation in response to cytokines synthesised by a synovial cell line. Biochim Biophys Acta. 1988 Sep 16; 971(2):148-56.
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  270. Lin CW, Phillips SL, Brinckerhoff CE, Georgescu HI, Bandara G, Evans CH. Induction of collagenase mRNA in lapine articular chondrocytes by synovial factors and interleukin-1. Arch Biochem Biophys. 1988 Jul; 264(1):351-4.
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  271. Boniface RJ, Cain PR, Evans CH. Articular responses to purified cartilage proteoglycans. Arthritis Rheum. 1988 Feb; 31(2):258-66.
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  272. Ferguson GM, Watanabe S, Georgescu HI, Evans CH. The synovial production of collagenase and chondrocyte activating factors in response to cobalt. J Orthop Res. 1988; 6(4):525-30.
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  273. Watanabe S, Georgescu HI, Mendelow D, Evans CH. Chondrocyte activation in response to factor(s) produced by a continuous line of lapine synovial fibroblasts. Exp Cell Res. 1986 Nov; 167(1):218-26.
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  274. Evans CH, Mazzocchi RA, Nelson DD, Rubash HE. Experimental arthritis induced by intraarticular injection of allogenic cartilaginous particles into rabbit knees. Arthritis Rheum. 1984 Feb; 27(2):200-7.
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  275. Edwards RP, Georgescu HI, Evans CH. Enhanced endocytosis by aging chondrocytes and fibroblasts. Exp Gerontol. 1984; 19(3):185-90.
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  276. Evans CH, Mears DC, McKnight JL. A preliminary ferrographic survey of the wear particles in human synovial fluid. Arthritis Rheum. 1981 Jul; 24(7):912-8.
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