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Edward Anthony Nardell, M.D.

TitleAssociate Professor in the Departments of Environmental Health and Immunology and Infectious Diseases
InstitutionHarvard School of Public Health
DepartmentEH - Exposure, Epidemiology and Risk Program
AddressBWH Div of Global Health Equity
709a
651 Huntington Ave
Boston MA 02115
Phone617/432-6937
Fax617/525-7719
Other Positions
TitleAssociate Professor of Medicine
InstitutionBrigham and Women's Hospital
DepartmentMedicine
DivisionSocial Medicine

TitleAssociate Professor of Global Health and Social Medicine
InstitutionBrigham and Women's Hospital
DepartmentGlobal Health and Social Medicine


 Mentoring 
 completed student projects
Butaro Airflow Experiment for the Reduction of Nosocomial TB Transmission in Butaro, Rwanda
International, 06/15/10 - 08/06/10

 Bibliographic 
 selected publications
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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  1. Dharmadhikari AS, Mphahlele M, Stoltz A, Venter K, Mathebula R, Masotla T, Lubbe W, Pagano M, First M, Jensen PA, van der Walt M, Nardell EA. Surgical face masks worn by patients with multidrug-resistant tuberculosis: impact on infectivity of air on a hospital ward. Am J Respir Crit Care Med. 2012 May 15; 185(10):1104-9.
    View in: PubMed
  2. Zhang J, Levin R, Angelo R, Vincent R, Brickner P, Ngai P, Nardell EA. A radiometry protocol for UVGI fixtures using a moving-mirror type gonioradiometer. J Occup Environ Hyg. 2012; 9(3):140-8.
    View in: PubMed
  3. Nardell EA. Programmatic management of multidrug-resistant tuberculosis--15 years later. Int J Tuberc Lung Dis. 2011 Oct; 15(10):1280.
    View in: PubMed
  4. Nardell E, Churchyard G. What is thwarting tuberculosis prevention in high-burden settings? N Engl J Med. 2011 Jul 7; 365(1):79-81.
    View in: PubMed
  5. Dharmadhikari AS, Basaraba RJ, Van Der Walt ML, Weyer K, Mphahlele M, Venter K, Jensen PA, First MW, Parsons S, McMurray DN, Orme IM, Nardell EA. Natural infection of guinea pigs exposed to patients with highly drug-resistant tuberculosis. Tuberculosis (Edinb). 2011 Jul; 91(4):329-38.
    View in: PubMed
  6. Dharmadhikari AS, Nardell E. Serial acid fast bacilli smear and culture conversion rates over 26 weeks in a cohort of 93 sputum culture–positive tuberculosis (TB). Clin Infect Dis. 2011 Feb 15; 52(4):554-6.
    View in: PubMed
  7. Nardell E, Dharmadhikari A. Turning off the spigot: reducing drug-resistant tuberculosis transmission in resource-limited settings. Int J Tuberc Lung Dis. 2010 Oct; 14(10):1233-43.
    View in: PubMed
  8. Churchyard GJ, Friedland G, Fielding K, Nardell E. Opportunities afforded by new drugs for tuberculosis. Lancet Infect Dis. 2010 Jun; 10(6):368-9.
    View in: PubMed
  9. Pollock NR, Kashino SS, Napolitano DR, Sloutsky A, Joshi S, Guillet J, Wong M, Nardell E, Campos-Neto A. Evaluation of the effect of treatment of latent tuberculosis infection on QuantiFERON-TB gold assay results. Infect Control Hosp Epidemiol. 2009 Apr; 30(4):392-5.
    View in: PubMed
  10. Radonovich LJ, Martinello RA, Hodgson M, Milton DK, Nardell EA. Influenza and ultraviolet germicidal irradiation. Virol J. 2008; 5:149.
    View in: PubMed
  11. Pollock NR, Campos-Neto A, Kashino S, Napolitano D, Behar SM, Shin D, Sloutsky A, Joshi S, Guillet J, Wong M, Nardell E. Discordant QuantiFERON-TB Gold test results among US healthcare workers with increased risk of latent tuberculosis infection: a problem or solution? Infect Control Hosp Epidemiol. 2008 Sep; 29(9):878-86.
    View in: PubMed
  12. Keshavjee S, Gelmanova IY, Farmer PE, Mishustin SP, Strelis AK, Andreev YG, Pasechnikov AD, Atwood S, Mukherjee JS, Rich ML, Furin JJ, Nardell EA, Kim JY, Shin SS. Treatment of extensively drug-resistant tuberculosis in Tomsk, Russia: a retrospective cohort study. Lancet. 2008 Oct 18; 372(9647):1403-9.
    View in: PubMed
  13. Dharmadhikari AS, Nardell EA. What animal models teach humans about tuberculosis. Am J Respir Cell Mol Biol. 2008 Nov; 39(5):503-8.
    View in: PubMed
  14. Nardell EA, Bucher SJ, Brickner PW, Wang C, Vincent RL, Becan-McBride K, James MA, Michael M, Wright JD. Safety of upper-room ultraviolet germicidal air disinfection for room occupants: results from the Tuberculosis Ultraviolet Shelter Study. Public Health Rep. 2008 Jan-Feb; 123(1):52-60.
    View in: PubMed
  15. Keshavjee S, Gelmanova IY, Pasechnikov AD, Mishustin SP, Andreev YG, Yedilbayev A, Furin JJ, Mukherjee JS, Rich ML, Nardell EA, Farmer PE, Kim JY, Shin SS. Treating multidrug-resistant tuberculosis in Tomsk, Russia: developing programs that address the linkage between poverty and disease. Ann N Y Acad Sci. 2008; 1136:1-11.
    View in: PubMed
  16. Friedland G, Churchyard GJ, Nardell E. Tuberculosis and HIV coinfection: current state of knowledge and research priorities. J Infect Dis. 2007 Aug 15; 196 Suppl 1:S1-3.
    View in: PubMed
  17. Bock NN, Jensen PA, Miller B, Nardell E. Tuberculosis infection control in resource-limited settings in the era of expanding HIV care and treatment. J Infect Dis. 2007 Aug 15; 196 Suppl 1:S108-13.
    View in: PubMed
  18. Nardell EA, Wallis RS. Here today--gone tomorrow: the case for transient acute tuberculosis infection. Am J Respir Crit Care Med. 2006 Oct 1; 174(7):734-5.
    View in: PubMed
  19. Hohmuth BA, Yamanija JC, Dayal AS, Nardell E, Salazar JJ, Smith Fawzi MC. Latent tuberculosis infection: risks to health care students at a hospital in Lima, Peru. Int J Tuberc Lung Dis. 2006 Oct; 10(10):1146-51.
    View in: PubMed
  20. Nardell EA, Mitnick CD. Are second-line drugs necessary to control multidrug-resistant tuberculosis? J Infect Dis. 2006 Nov 1; 194(9):1194-6.
    View in: PubMed
  21. Rich ML, Socci AR, Mitnick CD, Nardell EA, Becerra MC, Bonilla C, Bayona J, Seung KJ, Furin J, Farmer PE, Mukherjee JS. Representative drug susceptibility patterns for guiding design of retreatment regimens for MDR-TB. Int J Tuberc Lung Dis. 2006 Mar; 10(3):290-6.
    View in: PubMed
  22. Nardell EA, Fennelly KP . TB Transmission and Infection Control in Congregate Settings. Raviglione M, (Ed.)Tuberculosis: A comprehensive international approach. 2006.
  23. Cave D, Murray M, and Nardell E. Molecular epidemiology of tuberculosis. Tuberculosis And The Tubercle Bacillus, Stewart T. Cole, Kathleen Davis Eisenach (Editor), David N. McMurray, Willam R., Jr. Jacobs (eds.). 2006.
  24. Nardell EA, Rubin EJ. Once upon a time. . . improved intermittent therapy for tuberculosis--fact or fable? Am J Respir Crit Care Med. 2005 Dec 1; 172(11):1361-2.
    View in: PubMed
  25. First MW, Weker RA, Yasui S, Nardell EA. Monitoring human exposures to upper-room germicidal ultraviolet irradiation. J Occup Environ Hyg. 2005 May; 2(5):285-92.
    View in: PubMed
  26. Timperi R, Han LL, Sloutsky A, Becerra MC, Nardell EA, Salazar JJ, Smith-Fawzi MC. Drug resistance profiles of Mycobacterium tuberculosis isolates: five years' experience and insight into treatment strategies for MDR-TB in Lima, Peru. Int J Tuberc Lung Dis. 2005 Feb; 9(2):175-80.
    View in: PubMed
  27. Edwards DA, Man JC, Brand P, Katstra JP, Sommerer K, Stone HA, Nardell E, Scheuch G. Inhaling to mitigate exhaled bioaerosols. Proc Natl Acad Sci U S A. 2004 Dec 14; 101(50):17383-8.
    View in: PubMed
  28. Nardell EA, Fan D, Shepard JA, Mark EJ. Case records of the Massachusetts General Hospital. Weekly clinicopathological exercises. Case 22-2004. A 30-year-old woman with a pericardial effusion. N Engl J Med. 2004 Jul 15; 351(3):279-87.
    View in: PubMed
  29. Ko G, Thompson KM, Nardell EA. Estimation of tuberculosis risk on a commercial airliner. Risk Anal. 2004 Apr; 24(2):379-88.
    View in: PubMed
  30. Nardell EA. Catching droplet nuclei: toward a better understanding of tuberculosis transmission. Am J Respir Crit Care Med. 2004 Mar 1; 169(5):553-4.
    View in: PubMed
  31. Szot A, Jacobson FL, Munn S, Jazayeri D, Nardell E, Harrison D, Drosten R, Ohno-Machado L, Smeaton LM, Fraser HS. Diagnostic accuracy of chest X-rays acquired using a digital camera for low-cost teleradiology. Int J Med Inform. 2004 Feb; 73(1):65-73.
    View in: PubMed
  32. Nardell EA. Environmental infection control of tuberculosis. Semin Respir Infect. 2003 Dec; 18(4):307-19.
    View in: PubMed
  33. Nardell EA. Impact of DOTS and DOTS-plus on multidrug resistant TB: DOTS-plus strengthens, not weakens, DOTS programmes. BMJ. 2003 Jul 19; 327(7407):164; author reply 164.
    View in: PubMed
  34. Brickner PW, Vincent RL, First M, Nardell E, Murray M, Kaufman W. The application of ultraviolet germicidal irradiation to control transmission of airborne disease: bioterrorism countermeasure. Public Health Rep. 2003 Mar-Apr; 118(2):99-114.
    View in: PubMed
  35. Sharnprapai S, Miller AC, Suruki R, Corkren E, Etkind S, Driscoll J, McGarry M, Nardell E. Genotyping analyses of tuberculosis cases in U.S.- and foreign-born Massachusetts residents. Emerg Infect Dis. 2002 Nov; 8(11):1239-45.
    View in: PubMed
  36. Miller AC, Sharnprapai S, Suruki R, Corkren E, Nardell EA, Driscoll JR, McGarry M, Taber H, Etkind S. Impact of genotyping of Mycobacterium tuberculosis on public health practice in Massachusetts. Emerg Infect Dis. 2002 Nov; 8(11):1285-9.
    View in: PubMed
  37. Northrup JM, Miller AC, Nardell E, Sharnprapai S, Etkind S, Driscoll J, McGarry M, Taber HW, Elvin P, Qualls NL, Braden CR. Estimated costs of false laboratory diagnoses of tuberculosis in three patients. Emerg Infect Dis. 2002 Nov; 8(11):1264-70.
    View in: PubMed
  38. Miller AC, Butler WR, McInnis B, Boutotte J, Etkind S, Sharnprapai S, Bernardo J, Driscoll J, McGarry M, Crawford JT, Nardell E. Clonal relationships in a shelter-associated outbreak of drug-resistant tuberculosis: 1983-1997. Int J Tuberc Lung Dis. 2002 Oct; 6(10):872-8.
    View in: PubMed
  39. Nardell EA. Use and misuse of germicidal UV air disinfection for TB in high-prevalence settings. Int J Tuberc Lung Dis. 2002 Aug; 6(8):647-8.
    View in: PubMed
  40. Murray M, Nardell E. Molecular epidemiology of tuberculosis: achievements and challenges to current knowledge. Bull World Health Organ. 2002; 80(6):477-82.
    View in: PubMed
  41. Ko G, Burge HA, Nardell EA, Thompson KM. Estimation of tuberculosis risk and incidence under upper room ultraviolet germicidal irradiation in a waiting room in a hypothetical scenario. Risk Anal. 2001 Aug; 21(4):657-73.
    View in: PubMed
  42. Nardell EA . Transmission and Safety Issues. Friedman, L (Ed.)Tuberculsis: A Comprehensive Update. 2001; 49-75.
  43. Nardell EA. Issues facing TB control (4.1). Nosocomial tuberculosis transmission--problems of health care workers. Scott Med J. 2000 Oct; 45(5 Suppl):34-7.
    View in: PubMed
  44. Weyer K, Fourie PB, Nardell EA . A noxious synergy: tuberculosis and HIV in South Africa. Chapter 5. Farmer P, Becerra M, Kim JY (Eds.) The Global Impact of drug resistant tuberculosis. 2000.
  45. Nardell EA, Piessens, W . Transmission of tuberculosis. Reichman LB, Hershfield E, (Eds.)Tuberculosis - A Comprehensive International Approach. 2000; 215-240.
  46. Nardell EA. Tuberculosis. Spengler J, Samet JM, McCarthy JF (Eds.)Indoor Air Quality Handbook. 2000.
  47. Piessens W, Nardell EA . Pathogenesis of tuberculosis. Reichman LB, Hershfield E, (Eds.) Tuberculosis - A Comprehensive International Approach. 2000; 241-60.
  48. Nardell EA . Aerosol infections. Bloom B (Ed.)Encyclopedia of Microbiology. 2000; 69-77.
  49. Nardell EA. . Tuberculosis. Abrutyn E, Goldman DA, Scheckler WE. (Eds.) Saunders Infection Control Reference Service. 2000.
  50. Yokoe DS, Subramanyan GS, Nardell E, Sharnprapai S, McCray E, Platt R. Supplementing tuberculosis surveillance with automated data from health maintenance organizations. Emerg Infect Dis. 1999 Nov-Dec; 5(6):779-87.
    View in: PubMed
  51. Subramanyan GS, Yokoe DS, Sharnprapai S, Nardell E, McCray E, Platt R. Using automated pharmacy records to assess the management of tuberculosis. Emerg Infect Dis. 1999 Nov-Dec; 5(6):788-91.
    View in: PubMed
  52. Nardell EA. Air sampling for tuberculosis- homage to the lowly guinea pig. Chest. 1999 Oct; 116(4):1143-5.
    View in: PubMed
  53. Farmer P, Furin J, Bayona J, Becerra M, Henry C, Hiatt H, Kim JY, Mitnick C, Nardell E, Shin S. Management of MDR-TB in resource-poor countries. Int J Tuberc Lung Dis. 1999 Aug; 3(8):643-5.
    View in: PubMed
  54. Nardell EA, Macher JM. Respiratory infections - transmission and environmental control. Chapter 9. Macher JM (Ed.) Bioaerosols: Assessment and Control. 1999; 1-13.
  55. Farmer P, Bayona J, Becerra M, Furin J, Henry C, Hiatt H, Kim JY, Mitnick C, Nardell E, Shin S. The dilemma of MDR-TB in the global era. Int J Tuberc Lung Dis. 1998 Nov; 2(11):869-76.
    View in: PubMed
  56. Fennelly KP, Nardell EA. The relative efficacy of respirators and room ventilation in preventing occupational tuberculosis. Infect Control Hosp Epidemiol. 1998 Oct; 19(10):754-9.
    View in: PubMed
  57. Nardell EA. The role of ventilation in preventing nosocomial transmission of tuberculosis. Int J Tuberc Lung Dis. 1998 Sep; 2(9 Suppl 1):S110-7.
    View in: PubMed
  58. Nardell EA. Is a tuberculosis exposure a tuberculosis exposure if no one is infected? Infect Control Hosp Epidemiol. 1998 Jul; 19(7):484-6.
    View in: PubMed
  59. Farmer P, Nardell E. Nihilism and pragmatism in tuberculosis control. Am J Public Health. 1998 Jul; 88(7):1014-5.
    View in: PubMed
  60. Nardell EA. Tuberculosis. Abrutyn E, Goldman DA, Scheckler WE (Eds.) Saunders Infection Control Reference Service. 1998; 195-224.
  61. Singleton L, Turner M, Haskal R, Etkind S, Tricarico M, Nardell E. Long-term hospitalization for tuberculosis control. Experience with a medical-psychosocial inpatient unit. JAMA. 1997 Sep 10; 278(10):838-42.
    View in: PubMed
  62. Nardell EA, Kent D . Respiratory Infections in the Economically Disadvantaged. Fishman AP (Ed). Pulmonary Diseases and Disorders. 1997; 2187-2199.
  63. Nardell EA, Brickner PW. Tuberculosis in New York City: focal transmission of an often fatal disease. JAMA. 1996 Oct 16; 276(15):1259-60.
    View in: PubMed
  64. Nardell EA. Needles in haystacks: diagnosing tuberculosis under low prevalence conditions. Tuber Lung Dis. 1996 Oct; 77(5):389-90.
    View in: PubMed
  65. Nardell EA, Barnhart S, Permutt S . Control of Tuberculosis in Health Care Facilities: The Ratonal Approach to Patient Isolation, Building Ventilation, Air Filtration, Ultraviolet Air Disinfection, and Personal Respirators. Rom WN, Garay S (Eds.) Tuberculosis. 1996; 873-893.
  66. Nardell EA. Interrupting transmission from patients with unsuspected tuberculosis: a unique role for upper-room ultraviolet air disinfection. Am J Infect Control. 1995 Apr; 23(2):156-64.
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  67. Nardell EA. . Precautions to Prevent Transmission. Chapter 4. Rossman MD, MacGregor RR (Eds.) Tuberculosis: The Challenge of the 90's. 1995; 35-55.
  68. Brewer TF, Wilson ME, Nardell EA. BCG immunization: review of past experience, current use, and future prospects. Curr Clin Top Infect Dis. 1995; 15:253-70.
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  69. Brewer TF, Wilson ME, Nardell EA . BCG Immunization: review of past experience, current use and future prospects. Remington JS, Swartz MN (Eds.) Current Clinical Topics in Infectious Diseases. 1995.
  70. Nardell EA. . Respiratory infections among the economically disadvantaged. Neiderman MS, Sarosi G, Glassroth J (Eds.) Respiratory Infections - A scientific basis for management. 1994.
  71. Nardell EA. Transmission and Safety Issues. Chapter 3. Friedman, L (Ed.) Tuberculsis: A Comprehensive Update. 1994; 53-71.
  72. Nardell EA. Fans, filters, or rays? Pros and cons of the current environmental tuberculosis control technologies. Infect Control Hosp Epidemiol. 1993 Dec; 14(12):681-5.
    View in: PubMed
  73. Nardell EA. Environmental control of tuberculosis. Med Clin North Am. 1993 Nov; 77(6):1315-34.
    View in: PubMed
  74. Nardell EA. Beyond four drugs. Public health policy and the treatment of the individual patient with tuberculosis. Am Rev Respir Dis. 1993 Jul; 148(1):2-5.
    View in: PubMed
  75. Nardell EA. . Nosocomial tuberculosis transmission. Charney W, Schirman J.(Eds.)Essentials of Modern Hospital Safety. 1993.
  76. Nardell EA, Iseman MD, Kubica G, Riley RL, Stead WW, Urbach F. Multidrug-resistant tuberculosis. N Engl J Med. 1992 Oct 15; 327(16):1173-4.
    View in: PubMed
  77. Nardell EA. . Pathogenesis of tuberculosis. Chapter 5. Reichman LB, Hershfield E, (Eds.) Tuberculosis- A Comprehensive International Approach. 1992; 103-23.
  78. Etkind S, Boutotte J, Ford J, Singleton L, Nardell EA. Treating hard-to-treat tuberculosis patients in Massachusetts. Semin Respir Infect. 1991 Dec; 6(4):273-82.
    View in: PubMed
  79. Nardell EA, Keegan J, Cheney SA, Etkind SC. Airborne infection. Theoretical limits of protection achievable by building ventilation. Am Rev Respir Dis. 1991 Aug; 144(2):302-6.
    View in: PubMed
  80. Nardell EA. Nosocomial tuberculosis in the AIDS era: strategies for interrupting transmission in developed countries. Bull Int Union Tuberc Lung Dis. 1991 Jun-Sep; 66(2-3):107-11.
    View in: PubMed
  81. Nardell EA, Abrams A. Airborne infections in nursing homes. Neiderman MS (Ed.) Respiratory infections in the elderly. 1991.
  82. Nardell EA. Dodging droplet nuclei. Reducing the probability of nosocomial tuberculosis transmission in the AIDS era. Am Rev Respir Dis. 1990 Sep; 142(3):501-3.
    View in: PubMed
  83. Nardell EA, Etkind S. Guideline to Reduce the Chance of Airborne Tuberculosis (TB) Transmission from HIV-infected Patients. Charney W, Schirmer J (Eds.) Essentials of Modern Hospital Safety. 1990.
  84. Nardell EA. Tuberculosis in homeless, residential care facilities, prisons, nursing homes, and other close communities. Semin Respir Infect. 1989 Sep; 4(3):206-15.
    View in: PubMed
  85. Riley RL, Nardell EA. Clearing the air. The theory and application of ultraviolet air disinfection. Am Rev Respir Dis. 1989 May; 139(5):1286-94.
    View in: PubMed
  86. Thompson BT, Systrom DM, Nardell EA, Hales CA . Pulmonary Emergencies. Chapter 9. Wilkins EW (Ed.) Emergency Medicine. 1989.
  87. Steinberg JL, Nardell EA, Kass EH. Antibiotic prophylaxis after exposure to antibiotic-resistant Mycobacterium tuberculosis. Rev Infect Dis. 1988 Nov-Dec; 10(6):1208-19.
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  88. Nardell EA . Ultraviolet air disinfection to control tuberculosis in a shelter for the homeless. Kundsin R (Ed). Architectural design and indoor microbial pollution. 1988.
  89. Nardell E, McInnis B, Thomas B, Weidhaas S. Exogenous reinfection with tuberculosis in a shelter for the homeless. N Engl J Med. 1986 Dec 18; 315(25):1570-5.
    View in: PubMed
  90. Patterson WB, Craven DE, Schwartz DA, Nardell EA, Kasmer J, Noble J. Occupational hazards to hospital personnel. Ann Intern Med. 1985 May; 102(5):658-80.
    View in: PubMed
  91. Hales CA, Brandstetter RD, Miller LG, Nardell EA . Chapter 9 Pulmonary Emergencies. Wilkins EW, Dine JJ, Moncure AC, Gross PC (Eds). The MGH Textbook of Emergency Medicine. 1983.
  92. Nardell EA, Brody JS. Determinants of mechanical properties of rat lung during postnatal development. J Appl Physiol. 1982 Jul; 53(1):140-8.
    View in: PubMed
  93. Javaheri S, Nardell EA. Severe metabolic alkalosis: a case report. Br Med J (Clin Res Ed). 1981 Oct 17; 283(6298):1016-7.
    View in: PubMed
  94. Nardell EA. Chemotherapy for tuberculosis. Ann Intern Med. 1981 Jan; 94(1):138.
    View in: PubMed
  95. Nardell EA . Progress in the early detection of lung cancer. Current topics in the management of respiratory diseases. Snider G, and Brody J (Eds). 1981.
  96. Kearns TJ, Farer LS, Davidson PT, Alexander CE, Locks MO, Nardell EA. Symposium on the control and eradication of tuberculosis.Report of the meeting held in Boston, November 27-30, 1979. 1980.
  97. Javaheri S, Nardell EA, Kazemi H. Role of PCO2 as determinant of CSF [HCO-3] in metabolic acidosis. Respir Physiol. 1979 Feb; 36(2):155-66.
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  98. Nardell EA, Slate JL, Westphal DM, Hales CA . Pulmonary emergencies. Chapter 8. Wilkins EW, Moncure AC, Dineen JJ (Eds). The MGH Textbook of Emergency Medicine. 1978.
  99. Oaks WE, Nardell EA: . Chapter 11: Medical aspects of the patients in the shock and trauma unit. Matsumoto T (Ed): Current Management of Trauma in Surgery and General Practice. 1975.
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