 Aldebaran Hofer, M.D.,PH.D.
| Title | Associate Professor of Surgery |
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| Institution | Veterans Affairs Boston Healthcare System |
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| Department | Surgery |
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| Address | Brockton W. Roxbury VA Med Ctr
Room 2B111
1400 VFW Pkwy
West Roxbury MA 02132
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| Phone | 617/323-7700 |
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| Fax | 617/363-5592 |
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 Bibliographic
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications.
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Hofer AM. Interactions between calcium and cAMP signaling. Curr Med Chem. 2012 Dec 1; 19(34):5768-73.
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Maiellaro I, Lefkimmiatis K, Moyer MP, Curci S, Hofer AM. Termination and activation of store-operated cyclic AMP production. J Cell Mol Med. 2012 Nov; 16(11):2715-25.
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Cardone A, Lopez F, Affortunato F, Busco G, Hofer AM, Mallamaci R, Martinelli C, Colella M, Farinola GM. An aryleneethynylene fluorophore for cell membrane staining. Biochim Biophys Acta. 2012 Nov; 1818(11):2808-17.
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Murakami T, Ockinger J, Yu J, Byles V, McColl A, Hofer AM, Horng T. Critical role for calcium mobilization in activation of the NLRP3 inflammasome. Proc Natl Acad Sci U S A. 2012 Jul 10; 109(28):11282-7.
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Schwarzer C, Wong S, Shi J, Matthes E, Illek B, Ianowski JP, Arant RJ, Isacoff E, Vais H, Foskett JK, Maiellaro I, Hofer AM, Machen TE. Pseudomonas aeruginosa Homoserine lactone activates store-operated cAMP and cystic fibrosis transmembrane regulator-dependent Cl- secretion by human airway epithelia. J Biol Chem. 2010 Nov 5; 285(45):34850-63.
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Roy J, Lefkimmiatis K, Moyer MP, Curci S, Hofer AM. The {omega}-3 fatty acid eicosapentaenoic acid elicits cAMP generation in colonic epithelial cells via a "store-operated" mechanism. Am J Physiol Gastrointest Liver Physiol. 2010 Sep; 299(3):G715-22.
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Lefkimmiatis K, Moyer MP, Curci S, Hofer AM. "cAMP sponge": a buffer for cyclic adenosine 3', 5'-monophosphate. PLoS One. 2009; 4(11):e7649.
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Lefkimmiatis K, Srikanthan M, Maiellaro I, Moyer MP, Curci S, Hofer AM. Store-operated cyclic AMP signalling mediated by STIM1. Nat Cell Biol. 2009 Apr; 11(4):433-42.
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Zou J, Hofer AM, Lurtz MM, Gadda G, Ellis AL, Chen N, Huang Y, Holder A, Ye Y, Louis CF, Welshhans K, Rehder V, Yang JJ. Developing sensors for real-time measurement of high Ca2+ concentrations. Biochemistry. 2007 Oct 30; 46(43):12275-88.
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Hofer AM, Lefkimmiatis K. Extracellular calcium and cAMP: second messengers as "third messengers"? Physiology (Bethesda). 2007 Oct; 22:320-7.
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Hofer AM. Review series on the extracellular Ca(2+)-sensing receptor. J Cell Mol Med. 2007 Sep-Oct; 11(5):906-7.
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Gerbino A, Fistetto G, Colella M, Hofer AM, Debellis L, Caroppo R, Curci S. Real time measurements of water flow in amphibian gastric glands: modulation via the extracellular Ca2+-sensing receptor. J Biol Chem. 2007 May 4; 282(18):13477-86.
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Hofer AM. Measurement of free [Ca2+] changes in agonist-sensitive internal stores using compartmentalized fluorescent indicators. Methods Mol Biol. 2006; 312:229-47.
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Gerbino A, Ruder WC, Curci S, Pozzan T, Zaccolo M, Hofer AM. Termination of cAMP signals by Ca2+ and G(alpha)i via extracellular Ca2+ sensors: a link to intracellular Ca2+ oscillations. J Cell Biol. 2005 Oct 24; 171(2):303-12.
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Lau BW, Colella M, Ruder WC, Ranieri M, Curci S, Hofer AM. Deoxycholic acid activates protein kinase C and phospholipase C via increased Ca2+ entry at plasma membrane. Gastroenterology. 2005 Mar; 128(3):695-707.
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Hofer AM. Another dimension to calcium signaling: a look at extracellular calcium. J Cell Sci. 2005 Mar 1; 118(Pt 5):855-62.
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Hofer AM. Measurement of free [Ca²+] changes in agonist-sensitive internal stores using compartmentalized fluorescent indicators. Methods Mol Biol. 2005; 312:229-47.
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Caroppo R, Gerbino A, Fistetto G, Colella M, Debellis L, Hofer AM, Curci S. Extracellular calcium acts as a "third messenger" to regulate enzyme and alkaline secretion. J Cell Biol. 2004 Jul 5; 166(1):111-9.
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Hofer AM, Gerbino A, Caroppo R, Curci S. The extracellular calcium-sensing receptor and cell-cell signaling in epithelia. Cell Calcium. 2004 Mar; 35(3):297-306.
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Gerbino A, Hofer AM, McKay B, Lau BW, Soybel DI. Divalent cations regulate acidity within the lumen and tubulovesicle compartment of gastric parietal cells. Gastroenterology. 2004 Jan; 126(1):182-95.
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Caroppo R, Colella M, Colasuonno A, DeLuisi A, Debellis L, Curci S, Hofer AM. A reassessment of the effects of luminal [Ca2+] on inositol 1,4,5-trisphosphate-induced Ca2+ release from internal stores. J Biol Chem. 2003 Oct 10; 278(41):39503-8.
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Hofer AM, Brown EM. Extracellular calcium sensing and signalling. Nat Rev Mol Cell Biol. 2003 Jul; 4(7):530-8.
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De Luisi A, Hofer AM. Evidence that Ca(2+) cycling by the plasma membrane Ca(2+)-ATPase increases the 'excitability' of the extracellular Ca(2+)-sensing receptor. J Cell Sci. 2003 Apr 15; 116(Pt 8):1527-38.
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Caroppo R, Gerbino A, Debellis L, Kifor O, Soybel DI, Brown EM, Hofer AM, Curci S. Asymmetrical, agonist-induced fluctuations in local extracellular [Ca(2+)] in intact polarized epithelia. EMBO J. 2001 Nov 15; 20(22):6316-26.
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Hofer AM, Curci S, Doble MA, Brown EM, Soybel DI. Intercellular communication mediated by the extracellular calcium-sensing receptor. Nat Cell Biol. 2000 Jul; 2(7):392-8.
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Hofer AM. Measurement of free [Ca2+] changes in agonist-sensitive internal stores using compartmentalized fluorescent indicators. Methods Mol Biol. 1999; 114:249-65.
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Landolfi B, Curci S, Debellis L, Pozzan T, Hofer AM. Ca2+ homeostasis in the agonist-sensitive internal store: functional interactions between mitochondria and the ER measured In situ in intact cells. J Cell Biol. 1998 Sep 7; 142(5):1235-43.
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Hofer AM, Landolfi B, Debellis L, Pozzan T, Curci S. Free [Ca2+] dynamics measured in agonist-sensitive stores of single living intact cells: a new look at the refilling process. EMBO J. 1998 Apr 1; 17(7):1986-95.
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Hofer AM, Fasolato C, Pozzan T. Capacitative Ca2+ entry is closely linked to the filling state of internal Ca2+ stores: a study using simultaneous measurements of ICRAC and intraluminal [Ca2+]. J Cell Biol. 1998 Jan 26; 140(2):325-34.
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Hofer AM, Schulz I. Quantification of intraluminal free [Ca] in the agonist-sensitive internal calcium store using compartmentalized fluorescent indicators: some considerations. Cell Calcium. 1996 Sep; 20(3):235-42.
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Hofer AM, Curci S, Machen TE, Schulz I. ATP regulates calcium leak from agonist-sensitive internal calcium stores. FASEB J. 1996 Feb; 10(2):302-8.
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Hofer AM, Schlue WR, Curci S, Machen TE. Spatial distribution and quantitation of free luminal [Ca] within the InsP3-sensitive internal store of individual BHK-21 cells: ion dependence of InsP3-induced Ca release and reloading. FASEB J. 1995 Jun; 9(9):788-98.
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Hofer AM, Machen TE. Direct measurement of free Ca in organelles of gastric epithelial cells. Am J Physiol. 1994 Sep; 267(3 Pt 1):G442-51.
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Hofer AM, Machen TE. Technique for in situ measurement of calcium in intracellular inositol 1,4,5-trisphosphate-sensitive stores using the fluorescent indicator mag-fura-2. Proc Natl Acad Sci U S A. 1993 Apr 1; 90(7):2598-602.
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Hofer AM, Machen TE. K-induced alkalinization in all cell types of rabbit gastric glands: a novel K/H exchange mechanism. J Membr Biol. 1992 Mar; 126(3):245-56.
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