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Keywords
Last Name
Institution

Steven Kyle Grinspoon, M.D.

TitleProfessor of Medicine
InstitutionMassachusetts General Hospital
DepartmentMedicine
AddressMassachusetts General Hospital
Program in Nutritional Metabolism, LON207
55 Fruit St
Boston MA 02114
Phone617/726-3890
Fax617/724-8998

 Mentoring 
 completed student projects
Physiologic investigation of the renin-angiotensin-aldosterone system and associated insulin resistance in HIV-infected patients
Summer, 06/17/13 - 08/09/13
The Effects of Metformin on Insulin Resistance in HIV-positive Patients with Upodystrophy
Part Time, 10/01/99 - 06/01/99
Growth Hormone Dynamics in HIV-Associated Fat Redistribution PASTEUR
Summer, 06/26/00 - 08/31/00

 Bibliographic 
 selected publications
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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  1. Makimura H, Murphy CA, Feldpausch MN, Grinspoon SK. The Effects of Tesamorelin on Phosphocreatine Recovery in Obese Subjects With Reduced GH. J Clin Endocrinol Metab. 2014 Jan; 99(1):338-43.
    View in: PubMed
  2. Figueroa AL, Abdelbaky A, Truong QA, Corsini E, Macnabb MH, Lavender ZR, Lawler MA, Grinspoon SK, Brady TJ, Nasir K, Hoffmann U, Tawakol A. Measurement of Arterial Activity on Routine FDG PET/CT Images Improves Prediction of Risk of Future CV Events. JACC Cardiovasc Imaging. 2013 Dec; 6(12):1250-9.
    View in: PubMed
  3. Fitch KV, Srinivasa S, Abbara S, Burdo TH, Williams KC, Eneh P, Lo J, Grinspoon SK. Noncalcified Coronary Atherosclerotic Plaque and Immune Activation in HIV-Infected Women. J Infect Dis. 2013 Dec; 208(11):1737-46.
    View in: PubMed
  4. Tritos NA, Eppakayala S, Swearingen B, Hedley-Whyte ET, Miller KK, Nachtigall LB, Grinspoon SK, Biller BM, Klibanski A. Pathologic and clinical features of pituitary adenomas showing TSH immunoreactivity. Pituitary. 2013 Sep; 16(3):287-93.
    View in: PubMed
  5. Zanni MV, Abbara S, Lo J, Wai B, Hark D, Marmarelis E, Grinspoon SK. Increased coronary atherosclerotic plaque vulnerability by coronary computed tomography angiography in HIV-infected men. AIDS. 2013 May 15; 27(8):1263-72.
    View in: PubMed
  6. Fitch KV, Looby SE, Rope A, Eneh P, Hemphill L, Lee H, Grinspoon SK. Effects of aging and smoking on carotid intima-media thickness in HIV-infection. AIDS. 2013 Jan 2; 27(1):49-57.
    View in: PubMed
  7. Pereyra F, Lo J, Triant VA, Wei J, Buzon MJ, Fitch KV, Hwang J, Campbell JH, Burdo TH, Williams KC, Abbara S, Grinspoon SK. Increased coronary atherosclerosis and immune activation in HIV-1 elite controllers. AIDS. 2012 Nov 28; 26(18):2409-12.
    View in: PubMed
  8. Hwang JJ, Wei J, Abbara S, Grinspoon SK, Lo J. Receptor Activator of Nuclear Factor-?B Ligand (RANKL) and Its Relationship to Coronary Atherosclerosis in HIV Patients. J Acquir Immune Defic Syndr. 2012 Nov 1; 61(3):359-63.
    View in: PubMed
  9. Torriani M, Zanni MV, Fitch K, Stavrou E, Bredella MA, Lim R, Cypess AM, Grinspoon S. Increased FDG uptake in association with reduced extremity fat in HIV patients. Antivir Ther. 2013; 18(2):243-8.
    View in: PubMed
  10. Makimura H, Feldpausch MN, Rope AM, Hemphill LC, Torriani M, Lee H, Grinspoon SK. Metabolic effects of a growth hormone-releasing factor in obese subjects with reduced growth hormone secretion: a randomized controlled trial. J Clin Endocrinol Metab. 2012 Dec; 97(12):4769-79.
    View in: PubMed
  11. McCormack SE, Shaham O, McCarthy MA, Deik AA, Wang TJ, Gerszten RE, Clish CB, Mootha VK, Grinspoon SK, Fleischman A. Circulating branched-chain amino acid concentrations are associated with obesity and future insulin resistance in children and adolescents. Pediatr Obes. 2013 Feb; 8(1):52-61.
    View in: PubMed
  12. Zanni MV, Burdo TH, Makimura H, Williams KC, Grinspoon SK. Relationship between monocyte/macrophage activation marker soluble CD163 and insulin resistance in obese and normal-weight subjects. Clin Endocrinol (Oxf). 2012 Sep; 77(3):385-90.
    View in: PubMed
  13. Zanni MV, Grinspoon SK. HIV-specific immune dysregulation and atherosclerosis. Curr HIV/AIDS Rep. 2012 Sep; 9(3):200-5.
    View in: PubMed
  14. Chow FC, Regan S, Feske S, Meigs JB, Grinspoon SK, Triant VA. Comparison of ischemic stroke incidence in HIV-infected and non-HIV-infected patients in a US health care system. J Acquir Immune Defic Syndr. 2012 Aug 1; 60(4):351-8.
    View in: PubMed
  15. Subramanian S, Tawakol A, Burdo TH, Abbara S, Wei J, Vijayakumar J, Corsini E, Abdelbaky A, Zanni MV, Hoffmann U, Williams KC, Lo J, Grinspoon SK. Arterial inflammation in patients with HIV. JAMA. 2012 Jul 25; 308(4):379-86.
    View in: PubMed
  16. Stanley TL, Grinspoon SK. Body composition and metabolic changes in HIV-infected patients. J Infect Dis. 2012 Jun; 205 Suppl 3:S383-90.
    View in: PubMed
  17. Gandhi RT, Sax PE, Grinspoon SK. Metabolic and cardiovascular complications in HIV-infected patients: new challenges for a new age. J Infect Dis. 2012 Jun; 205 Suppl 3:S353-4.
    View in: PubMed
  18. Stanley TL, Falutz J, Marsolais C, Morin J, Soulban G, Mamputu JC, Assaad H, Turner R, Grinspoon SK. Reduction in visceral adiposity is associated with an improved metabolic profile in HIV-infected patients receiving tesamorelin. Clin Infect Dis. 2012 Jun; 54(11):1642-51.
    View in: PubMed
  19. Denny-Brown S, Stanley TL, Grinspoon SK, Makimura H. The association of macro- and micronutrient intake with growth hormone secretion. Growth Horm IGF Res. 2012 Jun-Aug; 22(3-4):102-7.
    View in: PubMed
  20. Fitch K, Abbara S, Lee H, Stavrou E, Sacks R, Michel T, Hemphill L, Torriani M, Grinspoon S. Effects of lifestyle modification and metformin on atherosclerotic indices among HIV-infected patients with the metabolic syndrome. AIDS. 2012 Mar 13; 26(5):587-97.
    View in: PubMed
  21. Makimura H, Feldpausch MN, Stanley TL, Sun N, Grinspoon SK. Reduced growth hormone secretion in obesity is associated with smaller LDL and HDL particle size. Clin Endocrinol (Oxf). 2012 Feb; 76(2):220-7.
    View in: PubMed
  22. Torriani M, Fitch K, Stavrou E, Bredella MA, Lim R, Sass CA, Cypess AM, Grinspoon S. Deiodinase 2 expression is increased in dorsocervical fat of patients with HIV-associated lipohypertrophy syndrome. J Clin Endocrinol Metab. 2012 Apr; 97(4):E602-7.
    View in: PubMed
  23. Fitch K, Grinspoon S. Nutritional and metabolic correlates of cardiovascular and bone disease in HIV-infected patients. Am J Clin Nutr. 2011 Dec; 94(6):1721S-1728S.
    View in: PubMed
  24. Burdo TH, Lo J, Abbara S, Wei J, DeLelys ME, Preffer F, Rosenberg ES, Williams KC, Grinspoon S. Soluble CD163, a novel marker of activated macrophages, is elevated and associated with noncalcified coronary plaque in HIV-infected patients. J Infect Dis. 2011 Oct 15; 204(8):1227-36.
    View in: PubMed
  25. McCormack SE, McCarthy MA, Farilla L, Hrovat MI, Systrom DM, Grinspoon SK, Fleischman A. Skeletal muscle mitochondrial function is associated with longitudinal growth velocity in children and adolescents. J Clin Endocrinol Metab. 2011 Oct; 96(10):E1612-8.
    View in: PubMed
  26. Grinspoon S, Fitch K. Therapy: HIV-associated dyslipidemia: the heart positive study. Nat Rev Endocrinol. 2011 Aug; 7(8):443-4.
    View in: PubMed
  27. Stanley TL, Falutz J, Mamputu JC, Soulban G, Potvin D, Grinspoon SK. Effects of tesamorelin on inflammatory markers in HIV patients with excess abdominal fat: relationship with visceral adipose reduction. AIDS. 2011 Jun 19; 25(10):1281-8.
    View in: PubMed
  28. Armstrong C, Liu E, Okuma J, Spiegelman D, Guerino C, Njelekela M, Grinspoon S, Fawzi W, Hawkins C. Dyslipidemia in an HIV-positive antiretroviral treatment-naive population in Dar es Salaam, Tanzania. J Acquir Immune Defic Syndr. 2011 Jun 1; 57(2):141-5.
    View in: PubMed
  29. Lin E, Grinspoon S, Wang T, Miller KK. Effects of oral contraceptives on natriuretic peptide levels in women with hypothalamic amenorrhea: a pilot study. Fertil Steril. 2011 Jun 30; 95(8):2605-7.
    View in: PubMed
  30. Ahima RS, Stanley TL, Khor VK, Zanni MV, Grinspoon SK. Estrogen sulfotransferase is expressed in subcutaneous adipose tissue of obese humans in association with TNF-alpha and SOCS3. J Clin Endocrinol Metab. 2011 Jul; 96(7):E1153-8.
    View in: PubMed
  31. Makimura H, Stanley TL, Chen CY, Branch KL, Grinspoon SK. Relationship of adiponectin to endogenous GH pulse secretion parameters in response to stimulation with a growth hormone releasing factor. Growth Horm IGF Res. 2011 Jun; 21(3):155-9.
    View in: PubMed
  32. Fitch KV, Stavrou E, Looby SE, Hemphill L, Jaff MR, Grinspoon SK. Associations of cardiovascular risk factors with two surrogate markers of subclinical atherosclerosis: endothelial function and carotid intima media thickness. Atherosclerosis. 2011 Aug; 217(2):437-40.
    View in: PubMed
  33. Fitch KV, Stanley TL, Looby SE, Rope AM, Grinspoon SK. Relationship between neck circumference and cardiometabolic parameters in HIV-infected and non-HIV-infected adults. Diabetes Care. 2011 Apr; 34(4):1026-31.
    View in: PubMed
  34. Triant VA, Grinspoon SK. Immune dysregulation and vascular risk in HIV-infected patients: implications for clinical care. J Infect Dis. 2011 Feb 15; 203(4):439-41.
    View in: PubMed
  35. Makimura H, Stanley TL, Sun N, Hrovat MI, Systrom DM, Grinspoon SK. The association of growth hormone parameters with skeletal muscle phosphocreatine recovery in adult men. J Clin Endocrinol Metab. 2011 Mar; 96(3):817-23.
    View in: PubMed
  36. Triant VA, Regan S, Lee H, Sax PE, Meigs JB, Grinspoon SK. Association of immunologic and virologic factors with myocardial infarction rates in a US healthcare system. J Acquir Immune Defic Syndr. 2010 Dec 15; 55(5):615-9.
    View in: PubMed
  37. Makimura H, Stanley TL, Sun N, Connelly JM, Hemphill LC, Hrovat MI, Systrom DM, Grinspoon SK. Increased skeletal muscle phosphocreatine recovery after sub-maximal exercise is associated with increased carotid intima-media thickness. Atherosclerosis. 2011 Mar; 215(1):214-7.
    View in: PubMed
  38. Fitch KV, Lo J, Abbara S, Ghoshhajra B, Shturman L, Soni A, Sacks R, Wei J, Grinspoon S. Increased coronary artery calcium score and noncalcified plaque among HIV-infected men: relationship to metabolic syndrome and cardiac risk parameters. J Acquir Immune Defic Syndr. 2010 Dec; 55(4):495-9.
    View in: PubMed
  39. Stanley TL, Zanni MV, Johnsen S, Rasheed S, Makimura H, Lee H, Khor VK, Ahima RS, Grinspoon SK. TNF-alpha antagonism with etanercept decreases glucose and increases the proportion of high molecular weight adiponectin in obese subjects with features of the metabolic syndrome. J Clin Endocrinol Metab. 2011 Jan; 96(1):E146-50.
    View in: PubMed
  40. Makimura H, Stanley TL, Sun N, Connelly JM, Hemphill LC, Grinspoon SK. The relationship between reduced testosterone, stimulated growth hormone secretion and increased carotid intima-media thickness in obese men. Clin Endocrinol (Oxf). 2010 Nov; 73(5):622-9.
    View in: PubMed
  41. Stanley TL, Chen CY, Branch KL, Makimura H, Grinspoon SK. Effects of a growth hormone-releasing hormone analog on endogenous GH pulsatility and insulin sensitivity in healthy men. J Clin Endocrinol Metab. 2011 Jan; 96(1):150-8.
    View in: PubMed
  42. Lo J, Abbara S, Rocha-Filho JA, Shturman L, Wei J, Grinspoon SK. Increased epicardial adipose tissue volume in HIV-infected men and relationships to body composition and metabolic parameters. AIDS. 2010 Aug 24; 24(13):2127-30.
    View in: PubMed
  43. Lo J, You SM, Liebau J, Lee H, Grinspoon S. Effects of low-dose growth hormone withdrawal in patients with HIV. JAMA. 2010 Jul 21; 304(3):272-4.
    View in: PubMed
  44. Zanni MV, Stanley TL, Makimura H, Chen CY, Grinspoon SK. Effects of TNF-alpha antagonism on E-selectin in obese subjects with metabolic dysregulation. Clin Endocrinol (Oxf). 2010 Jul; 73(1):48-54.
    View in: PubMed
  45. Falutz J, Mamputu JC, Potvin D, Moyle G, Soulban G, Loughrey H, Marsolais C, Turner R, Grinspoon S. Effects of tesamorelin (TH9507), a growth hormone-releasing factor analog, in human immunodeficiency virus-infected patients with excess abdominal fat: a pooled analysis of two multicenter, double-blind placebo-controlled phase 3 trials with safety extension data. J Clin Endocrinol Metab. 2010 Sep; 95(9):4291-304.
    View in: PubMed
  46. Fleischman A, Makimura H, Stanley TL, McCarthy MA, Kron M, Sun N, Chuzi S, Hrovat MI, Systrom DM, Grinspoon SK. Skeletal muscle phosphocreatine recovery after submaximal exercise in children and young and middle-aged adults. J Clin Endocrinol Metab. 2010 Sep; 95(9):E69-74.
    View in: PubMed
  47. Lo J, Grinspoon SK. Adrenal function in HIV infection. Curr Opin Endocrinol Diabetes Obes. 2010 Jun; 17(3):205-9.
    View in: PubMed
  48. Falutz J, Potvin D, Mamputu JC, Assaad H, Zoltowska M, Michaud SE, Berger D, Somero M, Moyle G, Brown S, Martorell C, Turner R, Grinspoon S. Effects of tesamorelin, a growth hormone-releasing factor, in HIV-infected patients with abdominal fat accumulation: a randomized placebo-controlled trial with a safety extension. J Acquir Immune Defic Syndr. 2010 Mar; 53(3):311-22.
    View in: PubMed
  49. Lo J, Abbara S, Shturman L, Soni A, Wei J, Rocha-Filho JA, Nasir K, Grinspoon SK. Increased prevalence of subclinical coronary atherosclerosis detected by coronary computed tomography angiography in HIV-infected men. AIDS. 2010 Jan 16; 24(2):243-53.
    View in: PubMed
  50. Raboud JM, Diong C, Carr A, Grinspoon S, Mulligan K, Sutinen J, Rozenbaum W, Cavalcanti RB, Wand H, Costagliola D, Walmsley S. A meta-analysis of six placebo-controlled trials of thiazolidinedione therapy for HIV lipoatrophy. HIV Clin Trials. 2010 Jan-Feb; 11(1):39-50.
    View in: PubMed
  51. Lo J, Looby SE, Wei J, Adler GK, Grinspoon SK. Increased aldosterone among HIV-infected women with visceral fat accumulation. AIDS. 2009 Nov 13; 23(17):2366-70.
    View in: PubMed
  52. Stanley TL, Levitsky LL, Grinspoon SK, Misra M. Effect of body mass index on peak growth hormone response to provocative testing in children with short stature. J Clin Endocrinol Metab. 2009 Dec; 94(12):4875-81.
    View in: PubMed
  53. Fleischman A, Kron M, Systrom DM, Hrovat M, Grinspoon SK. Mitochondrial function and insulin resistance in overweight and normal-weight children. J Clin Endocrinol Metab. 2009 Dec; 94(12):4923-30.
    View in: PubMed
  54. Makimura H, Stanley T, Mun D, Chen C, Wei J, Connelly JM, Hemphill LC, Grinspoon SK. Reduced growth hormone secretion is associated with increased carotid intima-media thickness in obesity. J Clin Endocrinol Metab. 2009 Dec; 94(12):5131-8.
    View in: PubMed
  55. Stanley TL, Joy T, Hadigan CM, Liebau JG, Makimura H, Chen CY, Thomas BJ, Weise SB, Robbins GK, Grinspoon SK. Effects of switching from lopinavir/ritonavir to atazanavir/ritonavir on muscle glucose uptake and visceral fat in HIV-infected patients. AIDS. 2009 Jul 17; 23(11):1349-57.
    View in: PubMed
  56. Triant VA, Meigs JB, Grinspoon SK. Association of C-reactive protein and HIV infection with acute myocardial infarction. J Acquir Immune Defic Syndr. 2009 Jul 1; 51(3):268-73.
    View in: PubMed
  57. Dolan Looby SE, Collins M, Lee H, Grinspoon S. Effects of long-term testosterone administration in HIV-infected women: a randomized, placebo-controlled trial. AIDS. 2009 May 15; 23(8):951-9.
    View in: PubMed
  58. Fitch KV, Guggina LM, Keough HM, Dolan Looby SE, Hadigan C, Anderson EJ, Hubbard J, Liebau JG, Johnsen S, Wei J, Makimura H, Stanley TL, Lo J, Grinspoon SK. Decreased respiratory quotient in relation to resting energy expenditure in HIV-infected and noninfected subjects. Metabolism. 2009 May; 58(5):608-15.
    View in: PubMed
  59. Lo J, You SM, Wei J, Canavan B, Grinspoon S. Relationship of peak growth hormone to cardiovascular parameters, waist circumference, lipids and glucose in HIV-infected patients and healthy adults. Clin Endocrinol (Oxf). 2009 Dec; 71(6):815-22.
    View in: PubMed
  60. Nachtigall LB, Valassi E, Lo J, McCarty D, Passeri J, Biller BM, Miller KK, Utz A, Grinspoon S, Lawson EA, Klibanski A. Gender effects on cardiac valvular function in hyperprolactinaemic patients receiving cabergoline: a retrospective study. Clin Endocrinol (Oxf). 2010 Jan; 72(1):53-8.
    View in: PubMed
  61. Makimura H, Wei J, Dolan-Looby SE, Ricchiuti V, Grinspoon S. Retinol-binding protein levels are increased in association with gonadotropin levels in healthy women. Metabolism. 2009 Apr; 58(4):479-87.
    View in: PubMed
  62. Grinspoon S. Strategies to augment growth-hormone secretion in obesity. Nat Clin Pract Endocrinol Metab. 2009 Mar; 5(3):123.
    View in: PubMed
  63. Grinspoon S. Diabetes mellitus, cardiovascular risk, and HIV disease. Circulation. 2009 Feb 17; 119(6):770-2.
    View in: PubMed
  64. Stanley TL, Grinspoon SK. GH/GHRH axis in HIV lipodystrophy. Pituitary. 2009; 12(2):143-52.
    View in: PubMed
  65. Falutz J, Allas S, Mamputu JC, Potvin D, Kotler D, Somero M, Berger D, Brown S, Richmond G, Fessel J, Turner R, Grinspoon S. Long-term safety and effects of tesamorelin, a growth hormone-releasing factor analogue, in HIV patients with abdominal fat accumulation. AIDS. 2008 Sep 12; 22(14):1719-28.
    View in: PubMed
  66. Makimura H, Stanley T, Mun D, You SM, Grinspoon S. The effects of central adiposity on growth hormone (GH) response to GH-releasing hormone-arginine stimulation testing in men. J Clin Endocrinol Metab. 2008 Nov; 93(11):4254-60.
    View in: PubMed
  67. Ranade K, Geese WJ, Noor M, Flint O, Tebas P, Mulligan K, Powderly W, Grinspoon SK, Dube MP. Genetic analysis implicates resistin in HIV lipodystrophy. AIDS. 2008 Aug 20; 22(13):1561-8.
    View in: PubMed
  68. Lo J, You SM, Canavan B, Liebau J, Beltrani G, Koutkia P, Hemphill L, Lee H, Grinspoon S. Low-dose physiological growth hormone in patients with HIV and abdominal fat accumulation: a randomized controlled trial. JAMA. 2008 Aug 6; 300(5):509-19.
    View in: PubMed
  69. Triant VA, Brown TT, Lee H, Grinspoon SK. Fracture prevalence among human immunodeficiency virus (HIV)-infected versus non-HIV-infected patients in a large U.S. healthcare system. J Clin Endocrinol Metab. 2008 Sep; 93(9):3499-504.
    View in: PubMed
  70. Grinspoon SK, Grunfeld C, Kotler DP, Currier JS, Lundgren JD, Dubé MP, Lipshultz SE, Hsue PY, Squires K, Schambelan M, Wilson PW, Yarasheski KE, Hadigan CM, Stein JH, Eckel RH. State of the science conference: Initiative to decrease cardiovascular risk and increase quality of care for patients living with HIV/AIDS: executive summary. Circulation. 2008 Jul 8; 118(2):198-210.
    View in: PubMed
  71. Lo J, Grinspoon S. Cardiovascular disease in HIV-infected patients: does HIV infection in and of itself increase cardiovascular risk? Curr Opin HIV AIDS. 2008 May; 3(3):207-13.
    View in: PubMed
  72. Hulgan T, Tebas P, Canter JA, Mulligan K, Haas DW, Dubé M, Grinspoon S, Robbins GK, Motsinger AA, Kallianpur AR. Hemochromatosis gene polymorphisms, mitochondrial haplogroups, and peripheral lipoatrophy during antiretroviral therapy. J Infect Dis. 2008 Mar 15; 197(6):858-66.
    View in: PubMed
  73. Justman JE, Hoover DR, Shi Q, Tan T, Anastos K, Tien PC, Cole SR, Hyman C, Karim R, Weber K, Grinspoon S. Longitudinal anthropometric patterns among HIV-infected and HIV-uninfected women. J Acquir Immune Defic Syndr. 2008 Mar 1; 47(3):312-9.
    View in: PubMed
  74. Joy T, Keogh HM, Hadigan C, Dolan SE, Fitch K, Liebau J, Johnsen S, Lo J, Grinspoon SK. Relation of body composition to body mass index in HIV-infected patients with metabolic abnormalities. J Acquir Immune Defic Syndr. 2008 Feb 1; 47(2):174-84.
    View in: PubMed
  75. Falutz J, Allas S, Blot K, Potvin D, Kotler D, Somero M, Berger D, Brown S, Richmond G, Fessel J, Turner R, Grinspoon S. Metabolic effects of a growth hormone-releasing factor in patients with HIV. N Engl J Med. 2007 Dec 6; 357(23):2359-70.
    View in: PubMed
  76. Hadigan C, Mazza S, Crum D, Grinspoon S. Rosiglitazone increases small dense low-density lipoprotein concentration and decreases high-density lipoprotein particle size in HIV-infected patients. AIDS. 2007 Nov 30; 21(18):2543-6.
    View in: PubMed
  77. Moore AF, Grinspoon SK. A dural tale. J Clin Endocrinol Metab. 2007 Sep; 92(9):3367-8.
    View in: PubMed
  78. Dubé MP, Komarow L, Mulligan K, Grinspoon SK, Parker RA, Robbins GK, Roubenoff R, Tebas P. Long-term body fat outcomes in antiretroviral-naive participants randomized to nelfinavir or efavirenz or both plus dual nucleosides. Dual X-ray absorptiometry results from A5005s, a substudy of Adult Clinical Trials Group 384. J Acquir Immune Defic Syndr. 2007 Aug 15; 45(5):508-14.
    View in: PubMed
  79. Joy T, Keogh HM, Hadigan C, Lee H, Dolan SE, Fitch K, Liebau J, Lo J, Johnsen S, Hubbard J, Anderson EJ, Grinspoon S. Dietary fat intake and relationship to serum lipid levels in HIV-infected patients with metabolic abnormalities in the HAART era. AIDS. 2007 Jul 31; 21(12):1591-600.
    View in: PubMed
  80. Joy T, Grinspoon SK. Adipose compartmentalization and insulin resistance among obese HIV-infected women: the role of intermuscular adipose tissue. Am J Clin Nutr. 2007 Jul; 86(1):5-6.
    View in: PubMed
  81. Triant VA, Grinspoon SK. Vascular dysfunction and cardiovascular complications. Curr Opin HIV AIDS. 2007 Jul; 2(4):299-304.
    View in: PubMed
  82. Dolan SE, Carpenter S, Grinspoon S. Effects of weight, body composition, and testosterone on bone mineral density in HIV-infected women. J Acquir Immune Defic Syndr. 2007 Jun 1; 45(2):161-7.
    View in: PubMed
  83. Dubé MP, Parker RA, Mulligan K, Tebas P, Robbins GK, Roubenoff R, Grinspoon SK. Effects of potent antiretroviral therapy on free testosterone levels and fat-free mass in men in a prospective, randomized trial: A5005s, a substudy of AIDS Clinical Trials Group Study 384. Clin Infect Dis. 2007 Jul 1; 45(1):120-6.
    View in: PubMed
  84. Grinspoon S. Use of thiazolidinediones in HIV-infected patients: what have we learned? J Infect Dis. 2007 Jun 15; 195(12):1731-3.
    View in: PubMed
  85. Triant VA, Lee H, Hadigan C, Grinspoon SK. Increased acute myocardial infarction rates and cardiovascular risk factors among patients with human immunodeficiency virus disease. J Clin Endocrinol Metab. 2007 Jul; 92(7):2506-12.
    View in: PubMed
  86. Lo J, Bernstein LE, Canavan B, Torriani M, Jackson MB, Ahima RS, Grinspoon SK. Effects of TNF-alpha neutralization on adipocytokines and skeletal muscle adiposity in the metabolic syndrome. Am J Physiol Endocrinol Metab. 2007 Jul; 293(1):E102-9.
    View in: PubMed
  87. Fleischman A, Johnsen S, Systrom DM, Hrovat M, Farrar CT, Frontera W, Fitch K, Thomas BJ, Torriani M, Côté HC, Grinspoon SK. Effects of a nucleoside reverse transcriptase inhibitor, stavudine, on glucose disposal and mitochondrial function in muscle of healthy adults. Am J Physiol Endocrinol Metab. 2007 Jun; 292(6):E1666-73.
    View in: PubMed
  88. Mulligan K, Yang Y, Wininger DA, Koletar SL, Parker RA, Alston-Smith BL, Schouten JT, Fielding RA, Basar MT, Grinspoon S. Effects of metformin and rosiglitazone in HIV-infected patients with hyperinsulinemia and elevated waist/hip ratio. AIDS. 2007 Jan 2; 21(1):47-57.
    View in: PubMed
  89. Johnsen S, Dolan SE, Fitch KV, Kanter JR, Hemphill LC, Connelly JM, Lees RS, Lee H, Grinspoon S. Carotid intimal medial thickness in human immunodeficiency virus-infected women: effects of protease inhibitor use, cardiac risk factors, and the metabolic syndrome. J Clin Endocrinol Metab. 2006 Dec; 91(12):4916-24.
    View in: PubMed
  90. Fitch KV, Anderson EJ, Hubbard JL, Carpenter SJ, Waddell WR, Caliendo AM, Grinspoon SK. Effects of a lifestyle modification program in HIV-infected patients with the metabolic syndrome. AIDS. 2006 Sep 11; 20(14):1843-50.
    View in: PubMed
  91. Hadigan C, Liebau J, Torriani M, Andersen R, Grinspoon S. Improved triglycerides and insulin sensitivity with 3 months of acipimox in human immunodeficiency virus-infected patients with hypertriglyceridemia. J Clin Endocrinol Metab. 2006 Nov; 91(11):4438-44.
    View in: PubMed
  92. Grinspoon S. Physiologic effects of GHRH in patients with HIV lipodystrophy: a model of acquired visceral adiposity. Nat Clin Pract Endocrinol Metab. 2006 Jul; 2(7):355.
    View in: PubMed
  93. Dolan SE, Frontera W, Librizzi J, Ljungquist K, Juan S, Dorman R, Cole ME, Kanter JR, Grinspoon S. Effects of a supervised home-based aerobic and progressive resistance training regimen in women infected with human immunodeficiency virus: a randomized trial. Arch Intern Med. 2006 Jun 12; 166(11):1225-31.
    View in: PubMed
  94. Dolan SE, Kanter JR, Grinspoon S. Longitudinal analysis of bone density in human immunodeficiency virus-infected women. J Clin Endocrinol Metab. 2006 Aug; 91(8):2938-45.
    View in: PubMed
  95. Miller KK, Lee EE, Lawson EA, Misra M, Minihan J, Grinspoon SK, Gleysteen S, Mickley D, Herzog D, Klibanski A. Determinants of skeletal loss and recovery in anorexia nervosa. J Clin Endocrinol Metab. 2006 Aug; 91(8):2931-7.
    View in: PubMed
  96. Sankalé JL, Tong Q, Hadigan CM, Tan G, Grinspoon SK, Kanki PJ, Hotamisligil GS. Regulation of adiponectin in adipocytes upon exposure to HIV-1. HIV Med. 2006 May; 7(4):268-74.
    View in: PubMed
  97. Bernstein LE, Berry J, Kim S, Canavan B, Grinspoon SK. Effects of etanercept in patients with the metabolic syndrome. Arch Intern Med. 2006 Apr 24; 166(8):902-8.
    View in: PubMed
  98. Mulligan K, Parker RA, Komarow L, Grinspoon SK, Tebas P, Robbins GK, Roubenoff R, Dubé MP. Mixed patterns of changes in central and peripheral fat following initiation of antiretroviral therapy in a randomized trial. J Acquir Immune Defic Syndr. 2006 Apr 15; 41(5):590-7.
    View in: PubMed
  99. Koutkia P, Eaton K, You SM, Breu J, Grinspoon S. Growth hormone secretion among HIV infected patients: effects of gender, race and fat distribution. AIDS. 2006 Apr 4; 20(6):855-62.
    View in: PubMed
  100. Lo J, Dolan SE, Kanter JR, Hemphill LC, Connelly JM, Lees RS, Grinspoon SK. Effects of obesity, body composition, and adiponectin on carotid intima-media thickness in healthy women. J Clin Endocrinol Metab. 2006 May; 91(5):1677-82.
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  101. Koutkia P, Berry J, Eaton K, Breu J, Grinspoon S. Increased adrenal androgen secretion with inhibition of 11beta-hydroxylase in HIV-infected women. Am J Physiol Endocrinol Metab. 2006 May; 290(5):E808-13.
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  102. Grinspoon S. Androgen deficiency and HIV infection. Clin Infect Dis. 2005 Dec 15; 41(12):1804-5.
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  103. Dubé MP, Parker RA, Tebas P, Grinspoon SK, Zackin RA, Robbins GK, Roubenoff R, Shafer RW, Wininger DA, Meyer WA, Snyder SW, Mulligan K. Glucose metabolism, lipid, and body fat changes in antiretroviral-naive subjects randomized to nelfinavir or efavirenz plus dual nucleosides. AIDS. 2005 Nov 4; 19(16):1807-18.
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  104. Torriani M, Thomas BJ, Barlow RB, Librizzi J, Dolan S, Grinspoon S. Increased intramyocellular lipid accumulation in HIV-infected women with fat redistribution. J Appl Physiol. 2006 Feb; 100(2):609-14.
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  105. Warren MP, Miller KK, Olson WH, Grinspoon SK, Friedman AJ. Effects of an oral contraceptive (norgestimate/ethinyl estradiol) on bone mineral density in women with hypothalamic amenorrhea and osteopenia: an open-label extension of a double-blind, placebo-controlled study. Contraception. 2005 Sep; 72(3):206-11.
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  106. Hadigan C, Kamin D, Liebau J, Mazza S, Barrow S, Torriani M, Rubin R, Weise S, Fischman A, Grinspoon S. Depot-specific regulation of glucose uptake and insulin sensitivity in HIV-lipodystrophy. Am J Physiol Endocrinol Metab. 2006 Feb; 290(2):E289-98.
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  107. Falutz J, Allas S, Kotler D, Thompson M, Koutkia P, Albu J, Trottier B, Routy JP, Cote P, Abribat T, Grinspoon S. A placebo-controlled, dose-ranging study of a growth hormone releasing factor in HIV-infected patients with abdominal fat accumulation. AIDS. 2005 Aug 12; 19(12):1279-87.
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  108. Johnsen S, Dolan SE, Fitch KV, Killilea KM, Shifren JL, Grinspoon SK. Absence of polycystic ovary syndrome features in human immunodeficiency virus-infected women despite significant hyperinsulinemia and truncal adiposity. J Clin Endocrinol Metab. 2005 Oct; 90(10):5596-604.
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  109. Canavan B, Salem RO, Schurgin S, Koutkia P, Lipinska I, Laposata M, Grinspoon S. Effects of physiological leptin administration on markers of inflammation, platelet activation, and platelet aggregation during caloric deprivation. J Clin Endocrinol Metab. 2005 Oct; 90(10):5779-85.
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  110. Koutkia P, Schurgin S, Berry J, Breu J, Lee BS, Klibanski A, Grinspoon S. Reciprocal changes in endogenous ghrelin and growth hormone during fasting in healthy women. Am J Physiol Endocrinol Metab. 2005 Nov; 289(5):E814-22.
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  111. Dolan SE, Hadigan C, Killilea KM, Sullivan MP, Hemphill L, Lees RS, Schoenfeld D, Grinspoon S. Increased cardiovascular disease risk indices in HIV-infected women. J Acquir Immune Defic Syndr. 2005 May 1; 39(1):44-54.
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  112. Kamin DS, Grinspoon SK. Cardiovascular disease in HIV-positive patients. AIDS. 2005 Apr 29; 19(7):641-52.
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  113. Grinspoon SK. Metabolic syndrome and cardiovascular disease in patients with human immunodeficiency virus. Am J Med. 2005 Apr; 118 Suppl 2:23S-28S.
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  114. Torriani M, Grinspoon S. Racial differences in fat distribution: the importance of intermuscular fat. Am J Clin Nutr. 2005 Apr; 81(4):731-2.
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  115. Miller KK, Grinspoon SK, Ciampa J, Hier J, Herzog D, Klibanski A. Medical findings in outpatients with anorexia nervosa. Arch Intern Med. 2005 Mar 14; 165(5):561-6.
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  116. Kamin D, Hadigan C, Lehrke M, Mazza S, Lazar MA, Grinspoon S. Resistin levels in human immunodeficiency virus-infected patients with lipoatrophy decrease in response to rosiglitazone. J Clin Endocrinol Metab. 2005 Jun; 90(6):3423-6.
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  117. Dolan SE, Grinspoon S. Androgen deficiency and the role of testosterone administration in HIV-infected women. J Acquir Immune Defic Syndr. 2005 Mar; 38 Suppl 1:S48-9.
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  118. Davis D, MacKay T, Utian W, Grinspoon S. Effect of estrogen receptors (reports from the FDA, NIH, ACOG, and NAMS) and the role of testosterone and bone density. J Acquir Immune Defic Syndr. 2005 Mar; 38 Suppl 1:S45-8.
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  119. Grinspoon S, Carr A. Cardiovascular risk and body-fat abnormalities in HIV-infected adults. N Engl J Med. 2005 Jan 6; 352(1):48-62.
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  120. Koutkia P, Canavan B, Breu J, Grinspoon S. Effects of growth hormone-releasing hormone on bone turnover in human immunodeficiency virus-infected men with fat accumulation. J Clin Endocrinol Metab. 2005 Apr; 90(4):2154-60.
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  121. Schurgin S, Canavan B, Koutkia P, Depaoli AM, Grinspoon S. Endocrine and metabolic effects of physiologic r-metHuLeptin administration during acute caloric deprivation in normal-weight women. J Clin Endocrinol Metab. 2004 Nov; 89(11):5402-9.
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  122. Koutkia P, Canavan B, Breu J, Grinspoon S. Growth hormone (GH) responses to GH-releasing hormone-arginine testing in human immunodeficiency virus lipodystrophy. J Clin Endocrinol Metab. 2005 Jan; 90(1):32-8.
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  123. Mulkern RV, Huang J, Vajapeyam S, Packard AB, Oshio K, Grinspoon S. Fat fractions and spectral T2 values in vertebral bone marrow in HIV- and non-HIV-infected men: a 1H spectroscopic imaging study. Magn Reson Med. 2004 Sep; 52(3):552-8.
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  124. Miller KK, Grinspoon S, Gleysteen S, Grieco KA, Ciampa J, Breu J, Herzog DB, Klibanski A. Preservation of neuroendocrine control of reproductive function despite severe undernutrition. J Clin Endocrinol Metab. 2004 Sep; 89(9):4434-8.
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  125. Miller KK, Grieco KA, Mulder J, Grinspoon S, Mickley D, Yehezkel R, Herzog DB, Klibanski A. Effects of risedronate on bone density in anorexia nervosa. J Clin Endocrinol Metab. 2004 Aug; 89(8):3903-6.
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  126. Swearingen B, Katznelson L, Miller K, Grinspoon S, Waltman A, Dorer DJ, Klibanski A, Biller BM. Diagnostic errors after inferior petrosal sinus sampling. J Clin Endocrinol Metab. 2004 Aug; 89(8):3752-63.
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  127. Grinspoon S, Miller KK, Herzog DB, Grieco KA, Klibanski A. Effects of estrogen and recombinant human insulin-like growth factor-I on ghrelin secretion in severe undernutrition. J Clin Endocrinol Metab. 2004 Aug; 89(8):3988-93.
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  128. Koutkia P, Canavan B, Breu J, Torriani M, Kissko J, Grinspoon S. Growth hormone-releasing hormone in HIV-infected men with lipodystrophy: a randomized controlled trial. JAMA. 2004 Jul 14; 292(2):210-8.
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  129. Schurgin S, Dolan S, Perlstein A, Sullivan MP, Aliabadi N, Grinspoon S. Effects of testosterone administration on growth hormone pulse dynamics in human immunodeficiency virus-infected women. J Clin Endocrinol Metab. 2004 Jul; 89(7):3290-7.
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  130. Bernstein EL, Koutkia P, Ljungquist K, Breu J, Canavan B, Grinspoon S. Acute regulation of adiponectin by free fatty acids. Metabolism. 2004 Jun; 53(6):790-3.
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  131. Koutkia P, Canavan B, Breu J, Johnson ML, Depaoli A, Grinspoon SK. Relation of leptin pulse dynamics to fat distribution in HIV-infected patients. Am J Clin Nutr. 2004 Jun; 79(6):1103-9.
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  132. Hadigan C, Yawetz S, Thomas A, Havers F, Sax PE, Grinspoon S. Metabolic effects of rosiglitazone in HIV lipodystrophy: a randomized, controlled trial. Ann Intern Med. 2004 May 18; 140(10):786-94.
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  133. Koutkia P, Canavan B, Breu J, Johnson ML, Grinspoon SK. Nocturnal ghrelin pulsatility and response to growth hormone secretagogues in healthy men. Am J Physiol Endocrinol Metab. 2004 Sep; 287(3):E506-12.
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  134. Driscoll SD, Meininger GE, Ljungquist K, Hadigan C, Torriani M, Klibanski A, Frontera WR, Grinspoon S. Differential effects of metformin and exercise on muscle adiposity and metabolic indices in human immunodeficiency virus-infected patients. J Clin Endocrinol Metab. 2004 May; 89(5):2171-8.
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  135. Dolan S, Wilkie S, Aliabadi N, Sullivan MP, Basgoz N, Davis B, Grinspoon S. Effects of testosterone administration in human immunodeficiency virus-infected women with low weight: a randomized placebo-controlled study. Arch Intern Med. 2004 Apr 26; 164(8):897-904.
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  136. Dolan SE, Huang JS, Killilea KM, Sullivan MP, Aliabadi N, Grinspoon S. Reduced bone density in HIV-infected women. AIDS. 2004 Feb 20; 18(3):475-83.
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  137. Driscoll SD, Meininger GE, Lareau MT, Dolan SE, Killilea KM, Hadigan CM, Lloyd-Jones DM, Klibanski A, Frontera WR, Grinspoon SK. Effects of exercise training and metformin on body composition and cardiovascular indices in HIV-infected patients. AIDS. 2004 Feb 20; 18(3):465-73.
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  138. Koutkia P, Grinspoon S. HIV-associated lipodystrophy: pathogenesis, prognosis, treatment, and controversies. Annu Rev Med. 2004; 55:303-17.
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  139. Chung RT, Casson DR, Murray G, Song S, Grinspoon S, Hadigan C. Alanine aminotransferase levels predict insulin resistance in HIV lipodystrophy. J Acquir Immune Defic Syndr. 2003 Dec 15; 34(5):534-6.
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  140. Koutkia P, Meininger G, Canavan B, Breu J, Grinspoon S. Metabolic regulation of growth hormone by free fatty acids, somatostatin, and ghrelin in HIV-lipodystrophy. Am J Physiol Endocrinol Metab. 2004 Feb; 286(2):E296-303.
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  141. Dolan S, Montagno A, Wilkie S, Aliabadi N, Sullivan M, Zahka N, Sherman JC, Grinspoon S. Neurocognitive function in HIV-infected patients with low weight and weight loss. J Acquir Immune Defic Syndr. 2003 Oct 1; 34(2):155-64.
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  142. Misra M, Soyka LA, Miller KK, Herzog DB, Grinspoon S, De Chen D, Neubauer G, Klibanski A. Serum osteoprotegerin in adolescent girls with anorexia nervosa. J Clin Endocrinol Metab. 2003 Aug; 88(8):3816-22.
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  143. Grinspoon SK, Friedman AJ, Miller KK, Lippman J, Olson WH, Warren MP. Effects of a triphasic combination oral contraceptive containing norgestimate/ethinyl estradiol on biochemical markers of bone metabolism in young women with osteopenia secondary to hypothalamic amenorrhea. J Clin Endocrinol Metab. 2003 Aug; 88(8):3651-6.
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  144. Misra M, Soyka LA, Miller KK, Grinspoon S, Levitsky LL, Klibanski A. Regional body composition in adolescents with anorexia nervosa and changes with weight recovery. Am J Clin Nutr. 2003 Jun; 77(6):1361-7.
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  145. Torriani M, Hadigan C, Jensen ME, Grinspoon S. Psoas muscle attenuation measurement with computed tomography indicates intramuscular fat accumulation in patients with the HIV-lipodystrophy syndrome. J Appl Physiol. 2003 Sep; 95(3):1005-10.
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  146. Koutkia P, Canavan B, Johnson ML, DePaoli A, Grinspoon S. Characterization of leptin pulse dynamics and relationship to fat mass, growth hormone, cortisol, and insulin. Am J Physiol Endocrinol Metab. 2003 Aug; 285(2):E372-9.
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  147. Tong Q, Sankalé JL, Hadigan CM, Tan G, Rosenberg ES, Kanki PJ, Grinspoon SK, Hotamisligil GS. Regulation of adiponectin in human immunodeficiency virus-infected patients: relationship to body composition and metabolic indices. J Clin Endocrinol Metab. 2003 Apr; 88(4):1559-64.
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  148. Grinspoon S, Mulligan K. Weight loss and wasting in patients infected with human immunodeficiency virus. Clin Infect Dis. 2003 Apr 1; 36(Suppl 2):S69-78.
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  149. Hadigan C, Meigs JB, Wilson PW, D'Agostino RB, Davis B, Basgoz N, Sax PE, Grinspoon S. Prediction of coronary heart disease risk in HIV-infected patients with fat redistribution. Clin Infect Dis. 2003 Apr 1; 36(7):909-16.
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  150. Grinspoon S, Miller K, Herzog D, Clemmons D, Klibanski A. Effects of recombinant human insulin-like growth factor (IGF)-I and estrogen administration on IGF-I, IGF binding protein (IGFBP)-2, and IGFBP-3 in anorexia nervosa: a randomized-controlled study. J Clin Endocrinol Metab. 2003 Mar; 88(3):1142-9.
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  151. Hadigan C, Rabe J, Meininger G, Aliabadi N, Breu J, Grinspoon S. Inhibition of lipolysis improves insulin sensitivity in protease inhibitor-treated HIV-infected men with fat redistribution. Am J Clin Nutr. 2003 Feb; 77(2):490-4.
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  152. Huang JS, Wilkie SJ, Dolan S, Gallafent JH, Aliabadi N, Sullivan MP, Grinspoon S. Reduced testosterone levels in human immunodeficiency virus-infected women with weight loss and low weight. Clin Infect Dis. 2003 Feb 15; 36(4):499-506.
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  153. Grinspoon S. Mechanisms and strategies for insulin resistance in acquired immune deficiency syndrome. Clin Infect Dis. 2003; 37 Suppl 2:S85-90.
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  154. Schambelan M, Benson CA, Carr A, Currier JS, Dubé MP, Gerber JG, Grinspoon SK, Grunfeld C, Kotler DP, Mulligan K, Powderly WG, Saag MS. Management of metabolic complications associated with antiretroviral therapy for HIV-1 infection: recommendations of an International AIDS Society-USA panel. J Acquir Immune Defic Syndr. 2002 Nov 1; 31(3):257-75.
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  155. Hadigan C, Rabe J, Grinspoon S. Sustained benefits of metformin therapy on markers of cardiovascular risk in human immunodeficiency virus-infected patients with fat redistribution and insulin resistance. J Clin Endocrinol Metab. 2002 Oct; 87(10):4611-5.
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  156. Soyka LA, Misra M, Frenchman A, Miller KK, Grinspoon S, Schoenfeld DA, Klibanski A. Abnormal bone mineral accrual in adolescent girls with anorexia nervosa. J Clin Endocrinol Metab. 2002 Sep; 87(9):4177-85.
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  157. Hadigan C, Borgonha S, Rabe J, Young V, Grinspoon S. Increased rates of lipolysis among human immunodeficiency virus-infected men receiving highly active antiretroviral therapy. Metabolism. 2002 Sep; 51(9):1143-7.
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  158. Meininger G, Hadigan C, Rietschel P, Grinspoon S. Body-composition measurements as predictors of glucose and insulin abnormalities in HIV-positive men. Am J Clin Nutr. 2002 Aug; 76(2):460-5.
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  159. Roubenoff R, Grinspoon S, Skolnik PR, Tchetgen E, Abad L, Spiegelman D, Knox T, Gorbach S. Role of cytokines and testosterone in regulating lean body mass and resting energy expenditure in HIV-infected men. Am J Physiol Endocrinol Metab. 2002 Jul; 283(1):E138-45.
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  160. Huang JS, Mulkern RV, Grinspoon S. Reduced intravertebral bone marrow fat in HIV-infected men. AIDS. 2002 Jun 14; 16(9):1265-9.
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  161. Grinspoon S, Thomas L, Miller K, Herzog D, Klibanski A. Effects of recombinant human IGF-I and oral contraceptive administration on bone density in anorexia nervosa. J Clin Endocrinol Metab. 2002 Jun; 87(6):2883-91.
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  162. Meininger G, Hadigan C, Laposata M, Brown J, Rabe J, Louca J, Aliabadi N, Grinspoon S. Elevated concentrations of free fatty acids are associated with increased insulin response to standard glucose challenge in human immunodeficiency virus-infected subjects with fat redistribution. Metabolism. 2002 Feb; 51(2):260-6.
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  163. Grinspoon S. Insulin resistance in the HIV-lipodystrophy syndrome. Trends Endocrinol Metab. 2001 Nov; 12(9):413-9.
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  164. Grinspoon S, Corcoran C, Stanley T, Rabe J, Wilkie S. Mechanisms of androgen deficiency in human immunodeficiency virus-infected women with the wasting syndrome. J Clin Endocrinol Metab. 2001 Sep; 86(9):4120-6.
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  165. Mylonakis E, Koutkia P, Grinspoon S. Diagnosis and treatment of androgen deficiency in human immunodeficiency virus-infected men and women. Clin Infect Dis. 2001 Sep 15; 33(6):857-64.
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  166. Grinspoon S, Gelato M. Editorial: The rational use of growth hormone in HIV-infected patients. J Clin Endocrinol Metab. 2001 Aug; 86(8):3478-9.
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  167. Huang JS, Wilkie SJ, Sullivan MP, Grinspoon S. Reduced bone density in androgen-deficient women with acquired immune deficiency syndrome wasting. J Clin Endocrinol Metab. 2001 Aug; 86(8):3533-9.
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  168. Hadigan C, Jeste S, Anderson EJ, Tsay R, Cyr H, Grinspoon S. Modifiable dietary habits and their relation to metabolic abnormalities in men and women with human immunodeficiency virus infection and fat redistribution. Clin Infect Dis. 2001 Sep 1; 33(5):710-7.
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  169. Fairfield WP, Treat M, Rosenthal DI, Frontera W, Stanley T, Corcoran C, Costello M, Parlman K, Schoenfeld D, Klibanski A, Grinspoon S. Effects of testosterone and exercise on muscle leanness in eugonadal men with AIDS wasting. J Appl Physiol. 2001 Jun; 90(6):2166-71.
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  170. Huang JS, Rietschel P, Hadigan CM, Rosenthal DI, Grinspoon S. Increased abdominal visceral fat is associated with reduced bone density in HIV-infected men with lipodystrophy. AIDS. 2001 May 25; 15(8):975-82.
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  171. Grinspoon S, Thomas L, Miller K, Pitts S, Herzog D, Klibanski A. Changes in regional fat redistribution and the effects of estrogen during spontaneous weight gain in women with anorexia nervosa. Am J Clin Nutr. 2001 May; 73(5):865-9.
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  172. Fairfield WP, Finkelstein JS, Klibanski A, Grinspoon SK. Osteopenia in eugonadal men with acquired immune deficiency syndrome wasting syndrome. J Clin Endocrinol Metab. 2001 May; 86(5):2020-6.
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  173. Rietschel P, Hadigan C, Corcoran C, Stanley T, Neubauer G, Gertner J, Grinspoon S. Assessment of growth hormone dynamics in human immunodeficiency virus-related lipodystrophy. J Clin Endocrinol Metab. 2001 Feb; 86(2):504-10.
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  174. Hadigan C, Meigs JB, Corcoran C, Rietschel P, Piecuch S, Basgoz N, Davis B, Sax P, Stanley T, Wilson PW, D'Agostino RB, Grinspoon S. Metabolic abnormalities and cardiovascular disease risk factors in adults with human immunodeficiency virus infection and lipodystrophy. Clin Infect Dis. 2001 Jan; 32(1):130-9.
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  175. Grinspoon S, Thomas E, Pitts S, Gross E, Mickley D, Miller K, Herzog D, Klibanski A. Prevalence and predictive factors for regional osteopenia in women with anorexia nervosa. Ann Intern Med. 2000 Nov 21; 133(10):790-4.
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  176. Rietschel P, Corcoran C, Stanley T, Basgoz N, Klibanski A, Grinspoon S. Prevalence of hypogonadism among men with weight loss related to human immunodeficiency virus infection who were receiving highly active antiretroviral therapy. Clin Infect Dis. 2000 Nov; 31(5):1240-4.
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  177. Hadigan CM, Anderson EJ, Miller KK, Hubbard JL, Herzog DB, Klibanski A, Grinspoon SK. Assessment of macronutrient and micronutrient intake in women with anorexia nervosa. Int J Eat Disord. 2000 Nov; 28(3):284-92.
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  178. Grinspoon S. Measurement and clinical significance of body-composition changes in HIV disease. Nutrition. 2000 Nov-Dec; 16(11-12):1102-4.
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  179. Corcoran C, Anderson EJ, Burrows B, Stanley T, Walsh M, Poulos AM, Grinspoon S. Comparison of total body potassium with other techniques for measuring lean body mass in men and women with AIDS wasting. Am J Clin Nutr. 2000 Oct; 72(4):1053-8.
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  180. Hadigan C, Corcoran C, Piecuch S, Rodriguez W, Grinspoon S. Hyperandrogenemia in human immunodeficiency virus-infected women with the lipodystrophy syndrome. J Clin Endocrinol Metab. 2000 Oct; 85(10):3544-50.
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  181. Grinspoon S, Corcoran C, Parlman K, Costello M, Rosenthal D, Anderson E, Stanley T, Schoenfeld D, Burrows B, Hayden D, Basgoz N, Klibanski A. Effects of testosterone and progressive resistance training in eugonadal men with AIDS wasting. A randomized, controlled trial. Ann Intern Med. 2000 Sep 5; 133(5):348-55.
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  182. Miller KK, Grinspoon S, Klibanski A. Cardiovascular risk markers in hypothalamic amenorrhoea. Clin Endocrinol (Oxf). 2000 Sep; 53(3):359-66.
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  183. Hadigan C, Corcoran C, Basgoz N, Davis B, Sax P, Grinspoon S. Metformin in the treatment of HIV lipodystrophy syndrome: A randomized controlled trial. JAMA. 2000 Jul 26; 284(4):472-7.
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  184. Hadigan C, Corcoran C, Stanley T, Piecuch S, Klibanski A, Grinspoon S. Fasting hyperinsulinemia in human immunodeficiency virus-infected men: relationship to body composition, gonadal function, and protease inhibitor use. J Clin Endocrinol Metab. 2000 Jan; 85(1):35-41.
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  185. Grinspoon S, Corcoran C, Stanley T, Baaj A, Basgoz N, Klibanski A. Effects of hypogonadism and testosterone administration on depression indices in HIV-infected men. J Clin Endocrinol Metab. 2000 Jan; 85(1):60-5.
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  186. Soyka LA, Grinspoon S, Levitsky LL, Herzog DB, Klibanski A. The effects of anorexia nervosa on bone metabolism in female adolescents. J Clin Endocrinol Metab. 1999 Dec; 84(12):4489-96.
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  187. Corcoran C, Grinspoon S. Treatments for wasting in patients with the acquired immunodeficiency syndrome. N Engl J Med. 1999 Jun 3; 340(22):1740-50.
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  188. Hadigan C, Miller K, Corcoran C, Anderson E, Basgoz N, Grinspoon S. Fasting hyperinsulinemia and changes in regional body composition in human immunodeficiency virus-infected women. J Clin Endocrinol Metab. 1999 Jun; 84(6):1932-7.
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  189. Grinspoon S, Miller K, Coyle C, Krempin J, Armstrong C, Pitts S, Herzog D, Klibanski A. Severity of osteopenia in estrogen-deficient women with anorexia nervosa and hypothalamic amenorrhea. J Clin Endocrinol Metab. 1999 Jun; 84(6):2049-55.
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  190. Swearingen B, Biller BM, Barker FG, Katznelson L, Grinspoon S, Klibanski A, Zervas NT. Long-term mortality after transsphenoidal surgery for Cushing disease. Ann Intern Med. 1999 May 18; 130(10):821-4.
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  191. Becker AE, Grinspoon SK, Klibanski A, Herzog DB. Eating disorders. N Engl J Med. 1999 Apr 8; 340(14):1092-8.
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  192. Corcoran C, Grinspoon S. The use of testosterone in the AIDS wasting syndrome. AIDS Clin Care. 1999 Apr; 11(4):25-6, 33-4.
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  193. Grinspoon S, Corcoran C, Anderson E, Hubbard J, Stanley T, Basgoz N, Klibanski A. Sustained anabolic effects of long-term androgen administration in men with AIDS wasting. Clin Infect Dis. 1999 Mar; 28(3):634-6.
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  194. Grinspoon S, Corcoran C, Rosenthal D, Stanley T, Parlman K, Costello M, Treat M, Davis S, Burrows B, Basgoz N, Klibanski A. Quantitative assessment of cross-sectional muscle area, functional status, and muscle strength in men with the acquired immunodeficiency syndrome wasting syndrome. J Clin Endocrinol Metab. 1999 Jan; 84(1):201-6.
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  195. Grinspoon S. Editorial comment: effects of HIV infection on the hypothalamic-pituitary-adrenal axis. AIDS Read. 1999 Jan-Feb; 9(1):46-7.
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  196. Grinspoon S, Corcoran C, Stanley T, Katznelson L, Klibanski A. Effects of androgen administration on the growth hormone-insulin-like growth factor I axis in men with acquired immunodeficiency syndrome wasting. J Clin Endocrinol Metab. 1998 Dec; 83(12):4251-6.
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  197. Swearingen B, Barker FG, Katznelson L, Biller BM, Grinspoon S, Klibanski A, Moayeri N, Black PM, Zervas NT. Long-term mortality after transsphenoidal surgery and adjunctive therapy for acromegaly. J Clin Endocrinol Metab. 1998 Oct; 83(10):3419-26.
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  198. Grinspoon S, Corcoran C, Miller K, Wang E, Hubbard J, Schoenfeld D, Anderson E, Basgoz N, Klibanski A. Determinants of increased energy expenditure in HIV-infected women. Am J Clin Nutr. 1998 Sep; 68(3):720-5.
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  199. Miller K, Corcoran C, Armstrong C, Caramelli K, Anderson E, Cotton D, Basgoz N, Hirschhorn L, Tuomala R, Schoenfeld D, Daugherty C, Mazer N, Grinspoon S. Transdermal testosterone administration in women with acquired immunodeficiency syndrome wasting: a pilot study. J Clin Endocrinol Metab. 1998 Aug; 83(8):2717-25.
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  200. Miller KK, Daly PA, Sentochnik D, Doweiko J, Samore M, Basgoz NO, Grinspoon SK. Pseudo-Cushing's syndrome in human immunodeficiency virus-infected patients. Clin Infect Dis. 1998 Jul; 27(1):68-72.
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  201. Grinspoon S, Corcoran C, Askari H, Schoenfeld D, Wolf L, Burrows B, Walsh M, Hayden D, Parlman K, Anderson E, Basgoz N, Klibanski A. Effects of androgen administration in men with the AIDS wasting syndrome. A randomized, double-blind, placebo-controlled trial. Ann Intern Med. 1998 Jul 1; 129(1):18-26.
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  202. Miller KK, Parulekar MS, Schoenfeld E, Anderson E, Hubbard J, Klibanski A, Grinspoon SK. Decreased leptin levels in normal weight women with hypothalamic amenorrhea: the effects of body composition and nutritional intake. J Clin Endocrinol Metab. 1998 Jul; 83(7):2309-12.
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  203. Corcoran CP, Grinspoon S. Diagnosis and treatment of endocrine disorders in the HIV-infected patient. J Int Assoc Physicians AIDS Care. 1998 Feb; 4(2):10-4, 34.
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  204. Grinspoon SK, Askari H, Landt ML, Nathan DM, Schoenfeld DA, Hayden DL, Laposata M, Hubbard J, Klibanski A. Effects of fasting and glucose infusion on basal and overnight leptin concentrations in normal-weight women. Am J Clin Nutr. 1997 Dec; 66(6):1352-6.
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  205. Grinspoon S, Corcoran C, Miller K, Biller BM, Askari H, Wang E, Hubbard J, Anderson EJ, Basgoz N, Heller HM, Klibanski A. Body composition and endocrine function in women with acquired immunodeficiency syndrome wasting. J Clin Endocrinol Metab. 1997 May; 82(5):1332-7.
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  206. Grinspoon S, Herzog D, Klibanski A. Mechanisms and treatment options for bone loss in anorexia nervosa. Psychopharmacol Bull. 1997; 33(3):399-404.
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  207. Grinspoon S, Corcoran C, Lee K, Burrows B, Hubbard J, Katznelson L, Walsh M, Guccione A, Cannan J, Heller H, Basgoz N, Klibanski A. Loss of lean body and muscle mass correlates with androgen levels in hypogonadal men with acquired immunodeficiency syndrome and wasting. J Clin Endocrinol Metab. 1996 Nov; 81(11):4051-8.
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  208. Grinspoon S, Baum H, Lee K, Anderson E, Herzog D, Klibanski A. Effects of short-term recombinant human insulin-like growth factor I administration on bone turnover in osteopenic women with anorexia nervosa. J Clin Endocrinol Metab. 1996 Nov; 81(11):3864-70.
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  209. Grinspoon S, Gulick T, Askari H, Landt M, Lee K, Anderson E, Ma Z, Vignati L, Bowsher R, Herzog D, Klibanski A. Serum leptin levels in women with anorexia nervosa. J Clin Endocrinol Metab. 1996 Nov; 81(11):3861-3.
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  210. Grinspoon SK, Baum HB, Kim V, Coggins C, Klibanski A. Decreased bone formation and increased mineral dissolution during acute fasting in young women. J Clin Endocrinol Metab. 1995 Dec; 80(12):3628-33.
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  211. Grinspoon SK, Baum HB, Peterson S, Klibanski A. Effects of rhIGF-I administration on bone turnover during short-term fasting. J Clin Invest. 1995 Aug; 96(2):900-6.
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  212. Grinspoon SK, Daniels GH. Case report: increased levothyroxine requirement in a patient with cryptic celiac-sprue disease. Endocr Pract. 1995 Mar-Apr; 1(2):88-90.
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  213. Grinspoon S, Clemmons D, Swearingen B, Klibanski A. Serum insulin-like growth factor-binding protein-3 levels in the diagnosis of acromegaly. J Clin Endocrinol Metab. 1995 Mar; 80(3):927-32.
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  214. Siegel LM, Grinspoon SK, Garvey GJ, Bilezikian JP. Sepsis and adrenal function. Trends Endocrinol Metab. 1994 Oct; 5(8):324-8.
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  215. Grinspoon SK, Donovan DS, Bilezikian JP. Aetiology and pathogenesis of hormonal and metabolic disorders in HIV infection. Baillieres Clin Endocrinol Metab. 1994 Oct; 8(4):735-55.
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  216. Grinspoon S. AIDS: endocrinologic and metabolic considerations. Ann Med. 1994 Oct; 26(5):321-3.
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  217. Grinspoon SK, Biller BM. Clinical review 62: Laboratory assessment of adrenal insufficiency. J Clin Endocrinol Metab. 1994 Oct; 79(4):923-31.
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  218. Grinspoon SK, Bilezikian JP. Endocrine manifestations of AIDS. Trends Endocrinol Metab. 1993 Dec; 4(10):315-7.
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  219. Grinspoon SK, Bilezikian JP. HIV disease and the endocrine system. N Engl J Med. 1992 Nov 5; 327(19):1360-5.
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