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Last Name
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Philip Stashenko, PH.D., D.M.D.

TitleAssociate Professor of Oral Medicine, Infection, and Immunity
InstitutionForsyth Institute
DepartmentOral Med - Infection + Immunity
AddressForsyth Institute
245 1st Street
Cambridge MA 02142
Phone617/262-5200

 Biography 
 awards and honors
1965 - 1969University Scholar
1968 - Phi Beta Kappa
1969 - cum laude
1972 - 1976Research Fellowship
1976 - 1977Research Fellowship
1977 - 1978Research Fellowship
1995 - Distinguished Faculty Award
1995 - Honorary Dental Society
1996 - Omicron Kappa Upsilon
2000 - IADR Pulp Biology Award Outstanding Research in Field
2004 - Mentor for Hesham Youssef, AAE Oral Research Presentation (first Student category)
2004 - Mentor for Ulrike Spaete, IADR Hatton Awardee (first posdoctoral category)
2006 - Identified as top 5% of NIH extramural grant recipients over the past 25 years

 Mentoring 
 completed student projects
Arg-gingipains as Virulence Factors in Periodontal Disease
Summer, 06/18/01 - 08/17/01
Gene Research
Summer, 07/01/03 - 08/31/03
Expression of IL-1 Isoforms as a diagnostic facator in periodontal lesions
Summer, 05/31/07 - 08/31/07
P. Gingivalis Gingipains as Virullence Factors in Periodontal Disease
Part Time/Continuation, 09/01/01 - 05/31/02
Effect of C-myc Inhibition on Osteoclastogenesis
Part Time/Continuation, 09/01/00 - 06/01/01
Expression and Function of Stra14 in Osteoclastogenesis
Part Time/Continuation, 09/01/01 - 12/31/01
Functional Analysis of Novel IL-1 Isoforms in Periapical Pathogenesis
Full Time/Year Long, 09/01/07 - 08/31/08
Expression and Function of Stra 14 During Osteoclastogenesis
Spanish, 06/18/01 - 08/24/01
Role and Relevance of Human EST 435890 in Osteoclast Differentiation
Summer, 06/19/00 - 08/11/00

 Bibliographic 
 selected publications
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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  1. Jiang H, Chen W, Zhu G, Zhang L, Tucker B, Hao L, Feng S, Ci H, Ma J, Wang L, Stashenko P, Li YP. RNAi-Mediated Silencing of Atp6i and Atp6i Haploinsufficiency Prevents Both Bone Loss and Inflammation in a Mouse Model of Periodontal Disease. PLoS One. 2013; 8(4):e58599.
    View in: PubMed
  2. Gao B, Chen W, Hao L, Zhu G, Feng S, Ci H, Zhou X, Stashenko P, Li YP. Inhibiting Periapical Lesions through AAV-RNAi Silencing of Cathepsin K. J Dent Res. 2013 Feb; 92(2):180-6.
    View in: PubMed
  3. Silva MJ, Kajiya M, AlShwaimi E, Sasaki H, Hong J, Ok P, Rezende TM, Pagonis TC, White RR, Paster BJ, Stashenko P, Kawai T. Bacteria-reactive immune response may induce RANKL-expressing T cells in the mouse periapical bone loss lesion. J Endod. 2012 Mar; 38(3):346-50.
    View in: PubMed
  4. Ohta K, Laborde NJ, Kajiya M, Shin J, Zhu T, Thondukolam AK, Min C, Kamata N, Karimbux NY, Stashenko P, Kawai T. Expression and possible immune-regulatory function of ghrelin in oral epithelium. J Dent Res. 2011 Nov; 90(11):1286-92.
    View in: PubMed
  5. Franco GC, Kajiya M, Nakanishi T, Ohta K, Rosalen PL, Groppo FC, Ernst CW, Boyesen JL, Bartlett JD, Stashenko P, Taubman MA, Kawai T. Inhibition of matrix metalloproteinase-9 activity by doxycycline ameliorates RANK ligand-induced osteoclast differentiation in vitro and in vivo. Exp Cell Res. 2011 Jun 10; 317(10):1454-64.
    View in: PubMed
  6. Ng R, Singh F, Papamanou DA, Song X, Patel C, Holewa C, Patel N, Klepac-Ceraj V, Fontana CR, Kent R, Pagonis TC, Stashenko PP, Soukos NS. Endodontic photodynamic therapy ex vivo. J Endod. 2011 Feb; 37(2):217-22.
    View in: PubMed
  7. Sasaki H, Suzuki N, Alshwaimi E, Xu Y, Battaglino R, Morse L, Stashenko P. 18ß-glycyrrhetinic acid inhibits periodontitis via glucocorticoid-independent nuclear factor-?B inactivation in interleukin-10-deficient mice. J Periodontal Res. 2010 Dec; 45(6):757-63.
    View in: PubMed
  8. Stashenko P, Van Dyke T, Tully P, Kent R, Sonis S, Tanner AC. Inflammation and genetic risk indicators for early periodontitis in adults. J Periodontol. 2011 Apr; 82(4):588-96.
    View in: PubMed
  9. Huang X, Morse LR, Xu Y, Zahradka J, Sychrová H, Stashenko P, Fan F, Battaglino RA. Mutational analysis of NHAoc/NHA2 in Saccharomyces cerevisiae. Biochim Biophys Acta. 2010 Dec; 1800(12):1241-7.
    View in: PubMed
  10. Xu Y, Morse LR, da Silva RA, Odgren PR, Sasaki H, Stashenko P, Battaglino RA. PAMM: a redox regulatory protein that modulates osteoclast differentiation. Antioxid Redox Signal. 2010 Jul 1; 13(1):27-37.
    View in: PubMed
  11. Alshwaimi E, Purcell P, Kawai T, Sasaki H, Oukka M, Campos-Neto A, Stashenko P. Regulatory T cells in mouse periapical lesions. J Endod. 2009 Sep; 35(9):1229-33.
    View in: PubMed
  12. Sasaki H, Suzuki N, Kent R, Kawashima N, Takeda J, Stashenko P. T cell response mediated by myeloid cell-derived IL-12 is responsible for Porphyromonas gingivalis-induced periodontitis in IL-10-deficient mice. J Immunol. 2008 May 1; 180(9):6193-8.
    View in: PubMed
  13. Fimple JL, Fontana CR, Foschi F, Ruggiero K, Song X, Pagonis TC, Tanner AC, Kent R, Doukas AG, Stashenko PP, Soukos NS. Photodynamic treatment of endodontic polymicrobial infection in vitro. J Endod. 2008 Jun; 34(6):728-34.
    View in: PubMed
  14. Leshem O, Kashino SS, Gonçalves RB, Suzuki N, Onodera M, Fujimura A, Sasaki H, Stashenko P, Campos-Neto A. Th1 biased response to a novel Porphyromonas gingivalis protein aggravates bone resorption caused by this oral pathogen. Microbes Infect. 2008 May; 10(6):664-72.
    View in: PubMed
  15. Morse LR, Nguyen HP, Jain N, Williams S, Tun CG, Battaglino RA, Stashenko P, Garshick E. Age and motor score predict osteoprotegerin level in chronic spinal cord injury. J Musculoskelet Neuronal Interact. 2008 Jan-Mar; 8(1):50-7.
    View in: PubMed
  16. Foschi F, Fontana CR, Ruggiero K, Riahi R, Vera A, Doukas AG, Pagonis TC, Kent R, Stashenko PP, Soukos NS. Photodynamic inactivation of Enterococcus faecalis in dental root canals in vitro. Lasers Surg Med. 2007 Dec; 39(10):782-7.
    View in: PubMed
  17. Morse L, Teng YD, Pham L, Newton K, Yu D, Liao WL, Kohler T, Müller R, Graves D, Stashenko P, Battaglino R. Spinal cord injury causes rapid osteoclastic resorption and growth plate abnormalities in growing rats (SCI-induced bone loss in growing rats). Osteoporos Int. 2008 May; 19(5):645-52.
    View in: PubMed
  18. Yang S, Chen W, Stashenko P, Li YP. Specificity of RGS10A as a key component in the RANKL signaling mechanism for osteoclast differentiation. J Cell Sci. 2007 Oct 1; 120(Pt 19):3362-71.
    View in: PubMed
  19. Battaglino RA, Pham L, Morse LR, Vokes M, Sharma A, Odgren PR, Yang M, Sasaki H, Stashenko P. NHA-oc/NHA2: a mitochondrial cation-proton antiporter selectively expressed in osteoclasts. Bone. 2008 Jan; 42(1):180-92.
    View in: PubMed
  20. Schulze-Späte U, Battaglino R, Fu J, Sharma A, Vokes M, Stashenko P. Brn3 transcription factors control terminal osteoclastogenesis. J Cell Biochem. 2007 Sep 1; 102(1):1-12.
    View in: PubMed
  21. Pham L, Purcell P, Morse L, Stashenko P, Battaglino RA. Expression analysis of nha-oc/NHA2: a novel gene selectively expressed in osteoclasts. Gene Expr Patterns. 2007 Oct; 7(8):846-51.
    View in: PubMed
  22. Kawai T, Paster BJ, Komatsuzawa H, Ernst CW, Goncalves RB, Sasaki H, Ouhara K, Stashenko PP, Sugai M, Taubman MA. Cross-reactive adaptive immune response to oral commensal bacteria results in an induction of receptor activator of nuclear factor-kappaB ligand (RANKL)-dependent periodontal bone resorption in a mouse model. Oral Microbiol Immunol. 2007 Jun; 22(3):208-15.
    View in: PubMed
  23. Battaglino R, Vokes M, Schulze-Späte U, Sharma A, Graves D, Kohler T, Müller R, Yoganathan S, Stashenko P. Fluoxetine treatment increases trabecular bone formation in mice. J Cell Biochem. 2007 Apr 15; 100(6):1387-94.
    View in: PubMed
  24. Keles A, Grunes B, Difuria C, Gagari E, Srinivasan V, Darendeliler MA, Muller R, Kent R, Stashenko P. Inhibition of tooth movement by osteoprotegerin vs. pamidronate under conditions of constant orthodontic force. Eur J Oral Sci. 2007 Apr; 115(2):131-6.
    View in: PubMed
  25. Ernst CW, Lee JE, Nakanishi T, Karimbux NY, Rezende TM, Stashenko P, Seki M, Taubman MA, Kawai T. Diminished forkhead box P3/CD25 double-positive T regulatory cells are associated with the increased nuclear factor-kappaB ligand (RANKL+) T cells in bone resorption lesion of periodontal disease. Clin Exp Immunol. 2007 May; 148(2):271-80.
    View in: PubMed
  26. Stashenko P, Gonçalves RB, Lipkin B, Ficarelli A, Sasaki H, Campos-Neto A. Th1 immune response promotes severe bone resorption caused by Porphyromonas gingivalis. Am J Pathol. 2007 Jan; 170(1):203-13.
    View in: PubMed
  27. Foschi F, Izard J, Sasaki H, Sambri V, Prati C, Müller R, Stashenko P. Treponema denticola in disseminating endodontic infections. J Dent Res. 2006 Aug; 85(8):761-5.
    View in: PubMed
  28. Soukos NS, Chen PS, Morris JT, Ruggiero K, Abernethy AD, Som S, Foschi F, Doucette S, Bammann LL, Fontana CR, Doukas AG, Stashenko PP. Photodynamic therapy for endodontic disinfection. J Endod. 2006 Oct; 32(10):979-84.
    View in: PubMed
  29. Gonçalves RB, Leshem O, Bernards K, Webb JR, Stashenko PP, Campos-Neto A. T-cell expression cloning of Porphyromonas gingivalis genes coding for T helper-biased immune responses during infection. Infect Immun. 2006 Jul; 74(7):3958-66.
    View in: PubMed
  30. Foschi F, Cavrini F, Montebugnoli L, Stashenko P, Sambri V, Prati C. Detection of bacteria in endodontic samples by polymerase chain reaction assays and association with defined clinical signs in Italian patients. Oral Microbiol Immunol. 2005 Oct; 20(5):289-95.
    View in: PubMed
  31. Gyurko R, Shoji H, Battaglino RA, Boustany G, Gibson FC, Genco CA, Stashenko P, Van Dyke TE. Inducible nitric oxide synthase mediates bone development and P. gingivalis-induced alveolar bone loss. Bone. 2005 Mar; 36(3):472-9.
    View in: PubMed
  32. Sasaki H, Okamatsu Y, Kawai T, Kent R, Taubman M, Stashenko P. The interleukin-10 knockout mouse is highly susceptible to Porphyromonas gingivalis-induced alveolar bone loss. J Periodontal Res. 2004 Dec; 39(6):432-41.
    View in: PubMed
  33. Dayan S, Stashenko P, Niederman R, Kupper TS. Oral epithelial overexpression of IL-1alpha causes periodontal disease. J Dent Res. 2004 Oct; 83(10):786-90.
    View in: PubMed
  34. Castro GF, Souza IP, Lopes S, Stashenko P, Teles RP. Salivary IgA to cariogenic bacteria in HIV-positive children and its correlation with caries prevalence and levels of cariogenic microorganisms. Oral Microbiol Immunol. 2004 Oct; 19(5):281-8.
    View in: PubMed
  35. Okamatsu Y, Kim D, Battaglino R, Sasaki H, Späte U, Stashenko P. MIP-1 gamma promotes receptor-activator-of-NF-kappa-B-ligand-induced osteoclast formation and survival. J Immunol. 2004 Aug 1; 173(3):2084-90.
    View in: PubMed
  36. Battaglino R, Fu J, Späte U, Ersoy U, Joe M, Sedaghat L, Stashenko P. Serotonin regulates osteoclast differentiation through its transporter. J Bone Miner Res. 2004 Sep; 19(9):1420-31.
    View in: PubMed
  37. Sasaki H, Balto K, Kawashima N, Eastcott J, Hoshino K, Akira S, Stashenko P. Gamma interferon (IFN-gamma) and IFN-gamma-inducing cytokines interleukin-12 (IL-12) and IL-18 do not augment infection-stimulated bone resorption in vivo. Clin Diagn Lab Immunol. 2004 Jan; 11(1):106-10.
    View in: PubMed
  38. von Stechow D, Balto K, Stashenko P, Müller R. Three-dimensional quantitation of periradicular bone destruction by micro-computed tomography. J Endod. 2003 Apr; 29(4):252-6.
    View in: PubMed
  39. Stashenko P, Niederman R, DePaola D. Basic and clinical research: issues of cost, manpower needs, and infrastructure. J Dent Educ. 2002 Aug; 66(8):927-38; discussion 939-41.
    View in: PubMed
  40. Niederman R, Kelderman H, Socransky S, Ostroff G, Genco C, Kent R, Stashenko P. Enhanced neutrophil emigration and Porphyromonas gingivalis reduction following PGG-glucan treatment of mice. Arch Oral Biol. 2002 Aug; 47(8):613-8.
    View in: PubMed
  41. Battaglino R, Kim D, Fu J, Vaage B, Fu XY, Stashenko P. c-myc is required for osteoclast differentiation. J Bone Miner Res. 2002 May; 17(5):763-73.
    View in: PubMed
  42. Balto K, White R, Mueller R, Stashenko P. A mouse model of inflammatory root resorption induced by pulpal infection. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2002 Apr; 93(4):461-8.
    View in: PubMed
  43. Niederman R, Westernoff T, Lee C, Mark LL, Kawashima N, Ullman-Culler M, Dewhirst FE, Paster BJ, Wagner DD, Mayadas T, Hynes RO, Stashenko P. Infection-mediated early-onset periodontal disease in P/E-selectin-deficient mice. J Clin Periodontol. 2001 Jun; 28(6):569-75.
    View in: PubMed
  44. Deng W, Stashenko P, Chen W, Liang Y, Shimizu K, Li YP. Characterization of mouse Atp6i gene, the gene promoter, and the gene expression. J Bone Miner Res. 2001 Jun; 16(6):1136-46.
    View in: PubMed
  45. Balto K, Sasaki H, Stashenko P. Interleukin-6 deficiency increases inflammatory bone destruction. Infect Immun. 2001 Feb; 69(2):744-50.
    View in: PubMed
  46. Sasaki H, Hou L, Belani A, Wang CY, Uchiyama T, Müller R, Stashenko P. IL-10, but not IL-4, suppresses infection-stimulated bone resorption in vivo. J Immunol. 2000 Oct 1; 165(7):3626-30.
    View in: PubMed
  47. Hou L, Sasakj H, Stashenko P. B-Cell deficiency predisposes mice to disseminating anaerobic infections: protection by passive antibody transfer. Infect Immun. 2000 Oct; 68(10):5645-51.
    View in: PubMed
  48. Hou L, Sasaki H, Stashenko P. Toll-like receptor 4-deficient mice have reduced bone destruction following mixed anaerobic infection. Infect Immun. 2000 Aug; 68(8):4681-7.
    View in: PubMed
  49. Mark LL, Haffajee AD, Socransky SS, Kent RL, Guerrero D, Kornman K, Newman M, Stashenko P. Effect of the interleukin-1 genotype on monocyte IL-1beta expression in subjects with adult periodontitis. J Periodontal Res. 2000 Jun; 35(3):172-7.
    View in: PubMed
  50. Balto K, Müller R, Carrington DC, Dobeck J, Stashenko P. Quantification of periapical bone destruction in mice by micro-computed tomography. J Dent Res. 2000 Jan; 79(1):35-40.
    View in: PubMed
  51. Li YP, Chen W, Liang Y, Li E, Stashenko P. Atp6i-deficient mice exhibit severe osteopetrosis due to loss of osteoclast-mediated extracellular acidification. Nat Genet. 1999 Dec; 23(4):447-51.
    View in: PubMed
  52. Gilad JZ, Teles R, Goodson M, White RR, Stashenko P. Development of a clindamycin-impregnated fiber as an intracanal medication in endodontic therapy. J Endod. 1999 Nov; 25(11):722-7.
    View in: PubMed
  53. Kawashima N, Niederman R, Hynes RO, Ullmann-Cullere M, Stashenko P. Infection-stimulated infraosseus inflammation and bone destruction is increased in P-/E-selectin knockout mice. Immunology. 1999 May; 97(1):117-23.
    View in: PubMed
  54. Kawashima N, Stashenko P. Expression of bone-resorptive and regulatory cytokines in murine periapical inflammation. Arch Oral Biol. 1999 Jan; 44(1):55-66.
    View in: PubMed
  55. Yelick PC, Abduljabbar TS, Stashenko P. zALK-8, a novel type I serine/threonine kinase receptor, is expressed throughout early zebrafish development. Dev Dyn. 1998 Apr; 211(4):352-61.
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  56. Stashenko P. Alumni Day '98 Symposium. The "M" in D.M.D.: new horizons in oral medicine in the 21st century. Harv Dent Bull. 1998; 7(2):15.
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  57. Stashenko P, Teles R, D'Souza R. Periapical inflammatory responses and their modulation. Crit Rev Oral Biol Med. 1998; 9(4):498-521.
    View in: PubMed
  58. Teles R, Wang CY, Stashenko P. Increased susceptibility of RAG-2 SCID mice to dissemination of endodontic infections. Infect Immun. 1997 Sep; 65(9):3781-7.
    View in: PubMed
  59. Wang CY, Tani-Ishii N, Stashenko P. Bone-resorptive cytokine gene expression in periapical lesions in the rat. Oral Microbiol Immunol. 1997 Apr; 12(2):65-71.
    View in: PubMed
  60. Petit MD, Stashenko P. Extracts of periodontopathic microorganisms lack functional superantigenic activity for murine T cells. J Periodontal Res. 1996 Nov; 31(8):517-24.
    View in: PubMed
  61. Yelick PC, Driever W, Neuhauss S, Stashenko P. Craniofacial cartilage development in zebrafish. Ann N Y Acad Sci. 1996 Jun 8; 785:360-1.
    View in: PubMed
  62. Li YP, Chen W, Stashenko P. Molecular cloning and characterization of a putative novel human osteoclast-specific 116-kDa vacuolar proton pump subunit. Biochem Biophys Res Commun. 1996 Jan 26; 218(3):813-21.
    View in: PubMed
  63. Li YP, Chen W, Stashenko P. Characterization of a silencer element in the first exon of the human osteocalcin gene. Nucleic Acids Res. 1995 Dec 25; 23(24):5064-72.
    View in: PubMed
  64. Li YP, Alexander M, Wucherpfennig AL, Yelick P, Chen W, Stashenko P. Cloning and complete coding sequence of a novel human cathepsin expressed in giant cells of osteoclastomas. J Bone Miner Res. 1995 Aug; 10(8):1197-202.
    View in: PubMed
  65. Tani-Ishii N, Wang CY, Stashenko P. Immunolocalization of bone-resorptive cytokines in rat pulp and periapical lesions following surgical pulp exposure. Oral Microbiol Immunol. 1995 Aug; 10(4):213-9.
    View in: PubMed
  66. Rahimi P, Wang CY, Stashenko P, Lee SK, Lorenzo JA, Graves DT. Monocyte chemoattractant protein-1 expression and monocyte recruitment in osseous inflammation in the mouse. Endocrinology. 1995 Jun; 136(6):2752-9.
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  67. Campos-Neto A, Mengel JO, Oliveira-Silva DA, Bonini PV, Taketomi E, Stashenko PP. Potent stimulation of murine B cells to proliferate and to secrete immunoglobulins by a lipoteichoic acid-like molecule produced by Clostridium botulinum C and D. Braz J Med Biol Res. 1995 May; 28(5):575-84.
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  68. Stashenko P, Wang CY, Riley E, Wu Y, Ostroff G, Niederman R. Reduction of infection-stimulated periapical bone resorption by the biological response modifier PGG glucan. J Dent Res. 1995 Jan; 74(1):323-30.
    View in: PubMed
  69. Stashenko P, Wang CY, Tani-Ishii N, Yu SM. Pathogenesis of induced rat periapical lesions. Oral Surg Oral Med Oral Pathol. 1994 Oct; 78(4):494-502.
    View in: PubMed
  70. Tani-Ishii N, Wang CY, Tanner A, Stashenko P. Changes in root canal microbiota during the development of rat periapical lesions. Oral Microbiol Immunol. 1994 Jun; 9(3):129-35.
    View in: PubMed
  71. Wucherpfennig AL, Li YP, Stetler-Stevenson WG, Rosenberg AE, Stashenko P. Expression of 92 kD type IV collagenase/gelatinase B in human osteoclasts. J Bone Miner Res. 1994 Apr; 9(4):549-56.
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  72. Li YP, Stashenko P. Characterization of a tumor necrosis factor-responsive element which down-regulates the human osteocalcin gene. Mol Cell Biol. 1993 Jun; 13(6):3714-21.
    View in: PubMed
  73. Wang CY, Stashenko P. Characterization of bone-resorbing activity in human periapical lesions. J Endod. 1993 Mar; 19(3):107-11.
    View in: PubMed
  74. Wang CY, Stashenko P. The role of interleukin-1 alpha in the pathogenesis of periapical bone destruction in a rat model system. Oral Microbiol Immunol. 1993 Feb; 8(1):50-6.
    View in: PubMed
  75. Wucherpfennig AL, Dewhirst FE, Stashenko P. Platelet activating factor increases intracellular calcium in isolated osteoclasts but does not modify bone resorption. Bone. 1993; 14(1):13-8.
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  76. Stashenko P, Yu SM, Wang CY. Kinetics of immune cell and bone resorptive responses to endodontic infections. J Endod. 1992 Sep; 18(9):422-6.
    View in: PubMed
  77. Li YP, Stashenko P. Proinflammatory cytokines tumor necrosis factor-alpha and IL-6, but not IL-1, down-regulate the osteocalcin gene promoter. J Immunol. 1992 Feb 1; 148(3):788-94.
    View in: PubMed
  78. Stashenko P, Wang CY. Characterization of bone resorptive mediators in active periapical lesions. Proc Finn Dent Soc. 1992; 88 Suppl 1:427-32.
    View in: PubMed
  79. Wang CY, Stashenko P. Kinetics of bone-resorbing activity in developing periapical lesions. J Dent Res. 1991 Oct; 70(10):1362-6.
    View in: PubMed
  80. Stashenko P, Jandinski JJ, Fujiyoshi P, Rynar J, Socransky SS. Tissue levels of bone resorptive cytokines in periodontal disease. J Periodontol. 1991 Aug; 62(8):504-9.
    View in: PubMed
  81. Stashenko P, Fujiyoshi P, Obernesser MS, Prostak L, Haffajee AD, Socransky SS. Levels of interleukin 1 beta in tissue from sites of active periodontal disease. J Clin Periodontol. 1991 Aug; 18(7):548-54.
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  82. Nguyen L, Dewhirst FE, Hauschka PV, Stashenko P. Interleukin-1 beta stimulates bone resorption and inhibits bone formation in vivo. Lymphokine Cytokine Res. 1991 Apr; 10(1-2):15-21.
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  83. Eftimiadi C, Stashenko P, Tonetti M, Mangiante PE, Massara R, Zupo S, Ferrarini M. Divergent effect of the anaerobic bacteria by-product butyric acid on the immune response: suppression of T-lymphocyte proliferation and stimulation of interleukin-1 beta production. Oral Microbiol Immunol. 1991 Feb; 6(1):17-23.
    View in: PubMed
  84. Jandinski JJ, Stashenko P, Feder LS, Leung CC, Peros WJ, Rynar JE, Deasy MJ. Localization of interleukin-1 beta in human periodontal tissue. J Periodontol. 1991 Jan; 62(1):36-43.
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  85. Obernesser MS, Socransky SS, Stashenko P. Limit of resolution of flow cytometry for the detection of selected bacterial species. J Dent Res. 1990 Sep; 69(9):1592-8.
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  86. Dewhirst FE, Ago JM, Stashenko P. Interleukin 1 interacts synergistically with forskolin and isobutylmethylxanthine in stimulating bone resorption in organ culture. Calcif Tissue Int. 1990 Jul; 47(1):1-7.
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  87. Stashenko P. Role of immune cytokines in the pathogenesis of periapical lesions. Endod Dent Traumatol. 1990 Jun; 6(3):89-96.
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  88. Stashenko P, Yu SM. T helper and T suppressor cell reversal during the development of induced rat periapical lesions. J Dent Res. 1989 May; 68(5):830-4.
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  89. Stashenko P, Obernesser MS, Dewhirst FE. Effect of immune cytokines on bone. Immunol Invest. 1989 Jan-May; 18(1-4):239-49.
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  90. Campos-Neto A, Stashenko PP. Interleukin 1 and T-cell activation. Immunol Today. 1988 May; 9(5):131.
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  91. Stashenko P, Dewhirst FE, Rooney ML, Desjardins LA, Heeley JD. Interleukin-1 beta is a potent inhibitor of bone formation in vitro. J Bone Miner Res. 1987 Dec; 2(6):559-65.
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  92. Yu SM, Stashenko P. Identification of inflammatory cells in developing rat periapical lesions. J Endod. 1987 Nov; 13(11):535-40.
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  93. Stoufi ED, Taubman MA, Ebersole JL, Smith DJ, Stashenko PP. Phenotypic analyses of mononuclear cells recovered from healthy and diseased human periodontal tissues. J Clin Immunol. 1987 May; 7(3):235-45.
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  94. Dewhirst FE, Ago JM, Peros WJ, Stashenko P. Synergism between parathyroid hormone and interleukin 1 in stimulating bone resorption in organ culture. J Bone Miner Res. 1987 Apr; 2(2):127-34.
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  95. Stashenko P, Dewhirst FE, Peros WJ, Kent RL, Ago JM. Synergistic interactions between interleukin 1, tumor necrosis factor, and lymphotoxin in bone resorption. J Immunol. 1987 Mar 1; 138(5):1464-8.
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  96. Stashenko P, Peros WJ, Gibbons RJ, Dearborn SM. Effect of monoclonal antibodies against lipoteichoic acid from the oral bacterium Streptococcus mutans on its adhesion and plaque-accumulation in vitro. Arch Oral Biol. 1986; 31(7):455-61.
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  97. Dewhirst FE, Stashenko PP, Mole JE, Tsurumachi T. Purification and partial sequence of human osteoclast-activating factor: identity with interleukin 1 beta. J Immunol. 1985 Oct; 135(4):2562-8.
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  98. Stashenko P, Resmini LM, Haffajee AD, Socransky SS. Helper and suppressor T cells in periodontal disease. J Periodontal Res. 1985 Sep; 20(5):515-21.
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  99. Stashenko P, Resmini LM, Haffajee AD, Socransky SS. T cell responses of periodontal disease patients and healthy subjects to oral microorganisms. J Periodontal Res. 1983 Nov; 18(6):587-600.
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  100. Stashenko P. Regulatory effect of monocytes on T cell proliferative responses to oral microbial antigens. Infect Immun. 1982 Dec; 38(3):938-47.
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  101. Bhan AK, Nadler LM, Stashenko P, McCluskey RT, Schlossman SF. Stages of B cell differentiation in human lymphoid tissue. J Exp Med. 1981 Sep 1; 154(3):737-49.
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  102. Pesando JM, Nadler LM, Lazarus H, Tomaselli KJ, Stashenko P, Ritz J, Levine H, Yunis EJ, Schlossman SF. Human cell lines express multiple populations of Ia-like molecules. Hum Immunol. 1981 Aug; 3(1):67-76.
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  103. Stashenko P, Nadler LM, Hardy R, Schlossman SF. Expression of cell surface markers after human B lymphocyte activation. Proc Natl Acad Sci U S A. 1981 Jun; 78(6):3848-52.
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  104. Nadler LM, Stashenko P, Hardy R, van Agthoven A, Terhorst C, Schlossman SF. Characterization of a human B cell-specific antigen (B2) distinct from B1. J Immunol. 1981 May; 126(5):1941-7.
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  105. Nadler LM, Stashenko P, Hardy R, Tomaselli KJ, Yunis EJ, Schlossman SF, Pesando JM. Monoclonal antibody identifies a new Ia-like (p29,34) polymorphic system linked to the HLA-D/DR region. Nature. 1981 Apr 16; 290(5807):591-3.
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  106. Nadler LM, Stashenko P, Hardy R, Pesando JM, Yunis EJ, Schlossman SF. Monoclonal antibodies defining serologically distinct HLA-D/DR related Ia-like antigens in man. Hum Immunol. 1981 Feb; 2(1):77-90.
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  107. Nadler LM, Ritz J, Hardy R, Pesando JM, Schlossman SF, Stashenko P. A unique cell surface antigen identifying lymphoid malignancies of B cell origin. J Clin Invest. 1981 Jan; 67(1):134-40.
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  108. Stashenko P, Nadler LM, Hardy R, Schlossman SF. Characterization of a human B lymphocyte-specific antigen. J Immunol. 1980 Oct; 125(4):1678-85.
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  109. Nadler LM, Stashenko P, Hardy R, Kaplan WD, Button LN, Kufe DW, Antman KH, Schlossman SF. Serotherapy of a patient with a monoclonal antibody directed against a human lymphoma-associated antigen. Cancer Res. 1980 Sep; 40(9):3147-54.
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  110. Stashenko P, Klinman NR. Analysis of the primary anti-(4-hydroxy-3-nitrophenyl) acetyl (NP) responsive B cells in BALB/C and B10.D2 mice. J Immunol. 1980 Aug; 125(2):531-7.
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  111. Nadler LM, Stashenko P, Hardy R, Schlossman SF. A monoclonal antibody defining a lymphoma-associated antigen in man. J Immunol. 1980 Aug; 125(2):570-7.
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  112. Stashenko PP, Bhan AK, Schlossman SF, McCluskey RT. Local transfer of delayed hypersensitivity and cutaneous basophil hypersensitivity. J Immunol. 1977 Dec; 119(6):1987-93.
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  113. Yaron A, Dunham EK, Stashenko PP, Campos-Neto A, Levine H, Schlossman SF. Immune ascites in the guinea pig: specificity of cells and antibody in an induced peritoneal exudate. J Immunol. 1977 Sep; 119(3):968-75.
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  114. Stashenko PP, Schlossman SF. Antigen recognition: the specificity of an isolated T lymphocyte population. J Immunol. 1977 Feb; 118(2):544-50.
    View in: PubMed
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