 Leo Cheng, Ph.D.
| Title | Associate Professor of Radiology |
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| Institution | Massachusetts General Hospital |
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| Department | Radiology |
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| Address | Massachusetts General Hospital
Pathology Research CNY-7, 149-7151
149 13th Street
Charlestown MA 02129
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| Phone | 617/724-6593 |
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| Fax | 617/726-5684 |
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 Mentoring Available: 01/01/08, Expires: 12/31/18 Analyzing human cancer metabolomics for disease diagnosis and patient prognosis using NMR spectroscopy and imaging, and molecular biology. Metabolic Characterization of Human Oral Squamous Cell Carcinoma Using Tissue Magnetic Resonance Spectroscopy Summer, 06/24/05 - 08/19/05 Bibliographic
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications.
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O'Grady G, Angeli TR, Du P, Lahr C, Lammers WJ, Windsor JA, Abell TL, Farrugia G, Pullan AJ, Cheng LK. Abnormal initiation and conduction of slow-wave activity in gastroparesis, defined by high-resolution electrical mapping. Gastroenterology. 2012 Sep; 143(3):589-98.e1-3.
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Jordan KW, Adkins CB, Cheng LL, Faquin WC. Application of magnetic-resonance-spectroscopy- based metabolomics to the fine-needle aspiration diagnosis of papillary thyroid carcinoma. Acta Cytol. 2011; 55(6):584-9.
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Kurth J, Defeo E, Cheng LL. Magnetic resonance spectroscopy: a promising tool for the diagnostics of human prostate cancer? Urol Oncol. 2011 Sep-Oct; 29(5):562-71.
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DeFeo EM, Wu CL, McDougal WS, Cheng LL. A decade in prostate cancer: from NMR to metabolomics. Nat Rev Urol. 2011 Jun; 8(6):301-11.
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Paskaranandavadivel N, Cheng LK, Du P, O'Grady G, Pullan AJ. Improved signal processing techniques for the analysis of high resolution serosal slow wave activity in the stomach. Conf Proc IEEE Eng Med Biol Soc. 2011; 2011:1737-40.
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Bull SH, O'Grady G, Cheng LK, Pullan AJ. A framework for the online analysis of multi-electrode gastric slow wave recordings. Conf Proc IEEE Eng Med Biol Soc. 2011; 2011:1741-4.
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Erickson JC, O'Grady G, Du P, Egbuji JU, Pullan AJ, Cheng LK. Automated gastric slow wave cycle partitioning and visualization for high-resolution activation time maps. Ann Biomed Eng. 2011 Jan; 39(1):469-83.
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DeFeo EM, Cheng LL. Characterizing human cancer metabolomics with ex vivo 1H HRMAS MRS. Technol Cancer Res Treat. 2010 Aug; 9(4):381-91.
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O'Grady G, Du P, Cheng LK, Egbuji JU, Lammers WJ, Windsor JA, Pullan AJ. Origin and propagation of human gastric slow-wave activity defined by high-resolution mapping. Am J Physiol Gastrointest Liver Physiol. 2010 Sep; 299(3):G585-92.
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Kaul D, Wu CL, Adkins CB, Jordan KW, Defeo EM, Habbel P, Peterson RT, McDougal WS, Pohl U, Cheng LL. Assessing prostate cancer growth with mRNA of spermine metabolic enzymes. Cancer Biol Ther. 2010 May; 9(9):736-42.
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Maxeiner A, Adkins CB, Zhang Y, Taupitz M, Halpern EF, McDougal WS, Wu CL, Cheng LL. Retrospective analysis of prostate cancer recurrence potential with tissue metabolomic profiles. Prostate. 2010 May 15; 70(7):710-7.
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Wu CL, Jordan KW, Ratai EM, Sheng J, Adkins CB, Defeo EM, Jenkins BG, Ying L, McDougal WS, Cheng LL. Metabolomic imaging for human prostate cancer detection. Sci Transl Med. 2010 Jan 27; 2(16):16ra8.
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Erickson JC, O'Grady G, Du P, Obioha C, Qiao W, Richards WO, Bradshaw LA, Pullan AJ, Cheng LK. Falling-edge, variable threshold (FEVT) method for the automated detection of gastric slow wave events in high-resolution serosal electrode recordings. Ann Biomed Eng. 2010 Apr; 38(4):1511-29.
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Jordan KW, Nordenstam J, Lauwers GY, Rothenberger DA, Alavi K, Garwood M, Cheng LL. Metabolomic characterization of human rectal adenocarcinoma with intact tissue magnetic resonance spectroscopy. Dis Colon Rectum. 2009 Mar; 52(3):520-5.
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Du P, Qiao W, O'Grady G, Egbuji JU, Lammers W, Cheng LK, Pullan AJ. Automated detection of gastric slow wave events and estimation of propagation velocity vector fields from serosal high-resolution mapping. Conf Proc IEEE Eng Med Biol Soc. 2009; 2009:2527-30.
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Jordan KW, Cheng LL. NMR-based metabolomics approach to target biomarkers for human prostate cancer. Expert Rev Proteomics. 2007 Jun; 4(3):389-400.
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Jordan KW, He W, Halpern EF, Wu CL, Cheng LL. Evaluation of Tissue Metabolites with High Resolution Magic Angle Spinning MR Spectroscopy Human Prostate Samples After Three-Year Storage at -80 degrees C. Biomark Insights. 2007; 2:147-54.
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Loening NM, Chamberlin AM, Zepeda AG, Gonzalez RG, Cheng LL. Quantification of phosphocholine and glycerophosphocholine with 31P edited 1H NMR spectroscopy. NMR Biomed. 2005 Nov; 18(7):413-20.
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Burns MA, Taylor JL, Wu CL, Zepeda AG, Bielecki A, Cory D, Cheng LL. Reduction of spinning sidebands in proton NMR of human prostate tissue with slow high-resolution magic angle spinning. Magn Reson Med. 2005 Jul; 54(1):34-42.
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Cheng LL, Burns MA, Taylor JL, He W, Halpern EF, McDougal WS, Wu CL. Metabolic characterization of human prostate cancer with tissue magnetic resonance spectroscopy. Cancer Res. 2005 Apr 15; 65(8):3030-4.
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Burns MA, He W, Wu CL, Cheng LL. Quantitative pathology in tissue MR spectroscopy based human prostate metabolomics. Technol Cancer Res Treat. 2004 Dec; 3(6):591-8.
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Wu CL, Taylor JL, He W, Zepeda AG, Halpern EF, Bielecki A, Gonzalez RG, Cheng LL. Proton high-resolution magic angle spinning NMR analysis of fresh and previously frozen tissue of human prostate. Magn Reson Med. 2003 Dec; 50(6):1307-11.
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Taylor JL, Wu CL, Cory D, Gonzalez RG, Bielecki A, Cheng LL. High-resolution magic angle spinning proton NMR analysis of human prostate tissue with slow spinning rates. Magn Reson Med. 2003 Sep; 50(3):627-32.
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Cheng LL, Newell K, Mallory AE, Hyman BT, Gonzalez RG. Quantification of neurons in Alzheimer and control brains with ex vivo high resolution magic angle spinning proton magnetic resonance spectroscopy and stereology. Magn Reson Imaging. 2002 Sep; 20(7):527-33.
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Tzika AA, Cheng LL, Goumnerova L, Madsen JR, Zurakowski D, Astrakas LG, Zarifi MK, Scott RM, Anthony DC, Gonzalez RG, Black PM. Biochemical characterization of pediatric brain tumors by using in vivo and ex vivo magnetic resonance spectroscopy. J Neurosurg. 2002 Jun; 96(6):1023-31.
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