Dariush Mozaffarian, M.D.
|Title||Associate Professor in the Department of Epidemiology|
|Institution||Harvard School of Public Health|
|Address||Harvard School of Public Health|
Building 2, Room 319
665 Huntington Ave
Boston MA 02115
|Title||Associate Professor of Medicine|
|Institution||Brigham and Women's Hospital|
|Division||Channing Division of Network Medicine|
Dariush Mozaffarian is a cardiologist and epidemiologist; Co-Director of the Program in Cardiovascular Epidemiology; Associate Professor in the Division of Cardiovascular Medicine, Brigham and Women’s Hospital and Harvard Medical School; and Associate Professor in the Department of Epidemiology at the Harvard School of Public Health. His research focuses on the effects of lifestyle, particularly diet, on cardiometabolic health and disease; on global impacts of suboptimal nutrition on chronic diseases; and on effectiveness of policies to improve diet and reduce disease risk.
Dr. Mozaffarian has authored or co-authored more than 200 scientific publications on lifestyle and cardiovascular health, including on global dietary burdens of disease, omega-3 fatty acids, trans fatty acids, diets and weight gain, and healthy dietary patterns. He has served on numerous committees and advisory boards, including for the World Health Organization, United Nations Food and Agriculture Organization, American Heart Association, Canadian government, and Chicago Council on Global Affairs. He chairs the 2010 Global Burden of Diseases Nutrition and Chronic Diseases Expert Group (NutriCoDE).
A Fellow of the American College of Cardiology and a Fellow of the American Heart Association, Dr. Mozaffarian received a BS in biological sciences from Stanford (with Honors, Phi Beta Kappa), an MD from Columbia (Alpha Omega Alpha), an MPH from University of Washington, and a Doctorate in Epidemiology from Harvard. He is board-certified in Cardiovascular Medicine and is clinically active on the cardiology service at Brigham and Women’s Hospital.
Dr. Mozaffarian’s main research interests are on the intersections of behavior and lifestyle, particularly dietary habits, with risk and cardiovascular and metabolic diseases; on the impact of suboptimal dietary habits on global cardiometabolic diseases; and on comparative effectiveness, cost-effectiveness, and translational implementation of dietary policies to improve health.
Areas of current focus include:
1. Circulating biomarkers of dietary and metabolic fatty acids and cardiovascular outcomes, intermediary phenotypes, and metabolic and physiologic pathways. Fatty acids of interest include individual omega-3, trans, saturated, polyunsaturated, and monounsaturated fats, including products of de novo lipogenesis, dairy fats, and long-chain monos. Current investigations involve several large prospective cohorts, including cohorts with novel serial measures over time of circulating phospholipid fatty acids; biomarker analyses in OPERA, a large multinational RCT of fish oil for prevention of atrial fibrillation; and involvement the CHARGE nutrition and fatty acid working groups, including leading a large consortium group of 17 cohorts worldwide having biomarker measures of fatty acids.
2. The influence of whole foods and diet patterns on cardiometabolic outcomes, including obesity, diabetes, and cardiovascular outcomes. Examples of current projects include assessments of dietary patterns and other lifestyle behaviors on incident heart failure and long-term weight gain.
3. Nutrition and global cardiometabolic health. Current projects include leadership of the Nutrition and Chronic Diseases Expert Group (NutriCoDE) of the Global Burden of Diseases study; analyses of global dietary patterns by country, age, and sex, including trends over time; and evaluation of global impacts of suboptimal diets, such as excess intakes of sodium, sugar-sweetened beverages, and processed meats; and insufficient intakes of fruits, vegetables, nuts, whole grains, vegetable oils, and fish.
4. Comparative effectiveness and cost-effectiveness of specific school, workplace, community, built-environment, economic, and regulatory strategies and policies to improve dietary habits and promote health. Examples of current projects include quantitative assessment of effectiveness of specific dietary policies, including heterogeneity by target population and world region; cost-effectiveness analyses of dietary policies to reduce chronic diseases; and translational implementation projects to test the effects of dietary policies on health in practice.
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