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Albert Hofman, Ph.D., M.D.

TitleAdjunct Professor of Epidemiology
InstitutionHarvard School of Public Health
DepartmentEpidemiology
AddressHarvard School of Public Health
Kresge Bldg, 9th Flr, Room 923 Epidemiology
677 Huntington Ave
Boston MA 02115
Phone617/432-3942

 Bibliographic 
 selected publications
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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  1. Michailidou K, Hall P, Gonzalez-Neira A, Ghoussaini M, Dennis J, Milne RL, Schmidt MK, Chang-Claude J, Bojesen SE, Bolla MK, Wang Q, Dicks E, Lee A, Turnbull C, Rahman N, Fletcher O, Peto J, Gibson L, Dos Santos Silva I, Nevanlinna H, Muranen TA, Aittomäki K, Blomqvist C, Czene K, Irwanto A, Liu J, Waisfisz Q, Meijers-Heijboer H, Adank M, van der Luijt RB, Hein R, Dahmen N, Beckman L, Meindl A, Schmutzler RK, Müller-Myhsok B, Lichtner P, Hopper JL, Southey MC, Makalic E, Schmidt DF, Uitterlinden AG, Hofman A, Hunter DJ, Chanock SJ, Vincent D, Bacot F, Tessier DC, Canisius S, Wessels LF, Haiman CA, Shah M, Luben R, Brown J, Luccarini C, Schoof N, Humphreys K, Li J, Nordestgaard BG, Nielsen SF, Flyger H, Couch FJ, Wang X, Vachon C, Stevens KN, Lambrechts D, Moisse M, Paridaens R, Christiaens MR, Rudolph A, Nickels S, Flesch-Janys D, Johnson N, Aitken Z, Aaltonen K, Heikkinen T, Broeks A, Veer LJ, van der Schoot CE, Guénel P, Truong T, Laurent-Puig P, Menegaux F, Marme F, Schneeweiss A, Sohn C, Burwinkel B, Zamora MP, Perez JI, Pita G, Alonso MR, Cox A, Brock IW, Cross SS, Reed MW, Sawyer EJ, Tomlinson I, Kerin MJ, Miller N, Henderson BE, Schumacher F, Le Marchand L, Andrulis IL, Knight JA, Glendon G, Mulligan AM, Lindblom A, Margolin S, Hooning MJ, Hollestelle A, van den Ouweland AM, Jager A, Bui QM, Stone J, Dite GS, Apicella C, Tsimiklis H, Giles GG, Severi G, Baglietto L, Fasching PA, Haeberle L, Ekici AB, Beckmann MW, Brenner H, Müller H, Arndt V, Stegmaier C, Swerdlow A, Ashworth A, Orr N, Jones M, Figueroa J, Lissowska J, Brinton L, Goldberg MS, Labrèche F, Dumont M, Winqvist R, Pylkäs K, Jukkola-Vuorinen A, Grip M, Brauch H, Hamann U, Brüning T, Radice P, Peterlongo P, Manoukian S, Bonanni B, Devilee P, Tollenaar RA, Seynaeve C, van Asperen CJ, Jakubowska A, Lubinski J, Jaworska K, Durda K, Mannermaa A, Kataja V, Kosma VM, Hartikainen JM, Bogdanova NV, Antonenkova NN, Dörk T, Kristensen VN, Anton-Culver H, Slager S, Toland AE, Edge S, Fostira F, Kang D, Yoo KY, Noh DY, Matsuo K, Ito H, Iwata H, Sueta A, Wu AH, Tseng CC, Van Den Berg D, Stram DO, Shu XO, Lu W, Gao YT, Cai H, Teo SH, Yip CH, Phuah SY, Cornes BK, Hartman M, Miao H, Lim WY, Sng JH, Muir K, Lophatananon A, Stewart-Brown S, Siriwanarangsan P, Shen CY, Hsiung CN, Wu PE, Ding SL, Sangrajrang S, Gaborieau V, Brennan P, McKay J, Blot WJ, Signorello LB, Cai Q, Zheng W, Deming-Halverson S, Shrubsole M, Long J, Simard J, Garcia-Closas M, Pharoah PD, Chenevix-Trench G, Dunning AM, Benitez J, Easton DF. Large-scale genotyping identifies 41 new loci associated with breast cancer risk. Nat Genet. 2013 Apr; 45(4):353-61.
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  2. Alonso A, Krijthe BP, Aspelund T, Stepas KA, Pencina MJ, Moser CB, Sinner MF, Sotoodehnia N, Fontes JD, Janssens AC, Kronmal RA, Magnani JW, Witteman JC, Chamberlain AM, Lubitz SA, Schnabel RB, Agarwal SK, McManus DD, Ellinor PT, Larson MG, Burke GL, Launer LJ, Hofman A, Levy D, Gottdiener JS, Kääb S, Couper D, Harris TB, Soliman EZ, Stricker BH, Gudnason V, Heckbert SR, Benjamin EJ. Simple Risk Model Predicts Incidence of Atrial Fibrillation in a Racially and Geographically Diverse Population: the CHARGE-AF Consortium. J Am Heart Assoc. 2013; 2(2):e000102.
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  3. Castaño-Betancourt MC, Rivadeneira F, Bierma-Zeinstra S, Kerkhof HJ, Hofman A, Uitterlinden AG, van Meurs JB. Bone parameters across different types of hip osteoarthritis and their relationship to osteoporotic fracture risk. Arthritis Rheum. 2013 Mar; 65(3):693-700.
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  4. Guxens M, Tiemeier H, Jansen PW, Raat H, Hofman A, Sunyer J, Jaddoe VW. Parental psychological distress during pregnancy and early growth in preschool children: the generation R study. Am J Epidemiol. 2013 Mar 15; 177(6):538-47.
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  5. de Groot M, Verhaaren BF, de Boer R, Klein S, Hofman A, van der Lugt A, Ikram MA, Niessen WJ, Vernooij MW. Changes in normal-appearing white matter precede development of white matter lesions. Stroke. 2013 Apr; 44(4):1037-42.
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  6. Devore EE, Feskens E, Ikram MA, den Heijer T, Vernooij M, van der Lijn F, Hofman A, Niessen WJ, Breteler MM. Total antioxidant capacity of the diet and major neurologic outcomes in older adults. Neurology. 2013 Mar 5; 80(10):904-10.
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  7. Verhoeven VJ, Hysi PG, Wojciechowski R, Fan Q, Guggenheim JA, Höhn R, Macgregor S, Hewitt AW, Nag A, Cheng CY, Yonova-Doing E, Zhou X, Ikram MK, Buitendijk GH, McMahon G, Kemp JP, Pourcain BS, Simpson CL, Mäkelä KM, Lehtimäki T, Kähönen M, Paterson AD, Hosseini SM, Wong HS, Xu L, Jonas JB, Pärssinen O, Wedenoja J, Yip SP, Ho DW, Pang CP, Chen LJ, Burdon KP, Craig JE, Klein BE, Klein R, Haller T, Metspalu A, Khor CC, Tai ES, Aung T, Vithana E, Tay WT, Barathi VA, Chen P, Li R, Liao J, Zheng Y, Ong RT, Döring A, Evans DM, Timpson NJ, Verkerk AJ, Meitinger T, Raitakari O, Hawthorne F, Spector TD, Karssen LC, Pirastu M, Murgia F, Ang W, Mishra A, Montgomery GW, Pennell CE, Cumberland PM, Cotlarciuc I, Mitchell P, Wang JJ, Schache M, Janmahasathian S, Jr RP, Lass JH, Chew E, Iyengar SK, Gorgels TG, Rudan I, Hayward C, Wright AF, Polasek O, Vatavuk Z, Wilson JF, Fleck B, Zeller T, Mirshahi A, Müller C, Uitterlinden AG, Rivadeneira F, Vingerling JR, Hofman A, Oostra BA, Amin N, Bergen AA, Teo YY, Rahi JS, Vitart V, Williams C, Baird PN, Wong TY, Oexle K, Pfeiffer N, Mackey DA, Young TL, van Duijn CM, Saw SM, Bailey-Wilson JE, Stambolian D, Klaver CC, Hammond CJ. Genome-wide meta-analyses of multiancestry cohorts identify multiple new susceptibility loci for refractive error and myopia. Nat Genet. 2013 Mar; 45(3):314-8.
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  8. Porcu E, Medici M, Pistis G, Volpato CB, Wilson SG, Cappola AR, Bos SD, Deelen J, den Heijer M, Freathy RM, Lahti J, Liu C, Lopez LM, Nolte IM, O'Connell JR, Tanaka T, Trompet S, Arnold A, Bandinelli S, Beekman M, Böhringer S, Brown SJ, Buckley BM, Camaschella C, de Craen AJ, Davies G, de Visser MC, Ford I, Forsen T, Frayling TM, Fugazzola L, Gögele M, Hattersley AT, Hermus AR, Hofman A, Houwing-Duistermaat JJ, Jensen RA, Kajantie E, Kloppenburg M, Lim EM, Masciullo C, Mariotti S, Minelli C, Mitchell BD, Nagaraja R, Netea-Maier RT, Palotie A, Persani L, Piras MG, Psaty BM, Räikkönen K, Richards JB, Rivadeneira F, Sala C, Sabra MM, Sattar N, Shields BM, Soranzo N, Starr JM, Stott DJ, Sweep FC, Usala G, van der Klauw MM, van Heemst D, van Mullem A, H Vermeulen S, Visser WE, Walsh JP, Westendorp RG, Widen E, Zhai G, Cucca F, Deary IJ, Eriksson JG, Ferrucci L, Fox CS, Jukema JW, Kiemeney LA, Pramstaller PP, Schlessinger D, Shuldiner AR, Slagboom EP, Uitterlinden AG, Vaidya B, Visser TJ, Wolffenbuttel BH, Meulenbelt I, Rotter JI, Spector TD, Hicks AA, Toniolo D, Sanna S, Peeters RP, Naitza S. A meta-analysis of thyroid-related traits reveals novel Loci and gender-specific differences in the regulation of thyroid function. PLoS Genet. 2013 Feb; 9(2):e1003266.
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  9. de Bruijn RF, Schrijvers EM, de Groot KA, Witteman JC, Hofman A, Franco OH, Koudstaal PJ, Ikram MA. The association between physical activity and dementia in an elderly population: the Rotterdam Study. Eur J Epidemiol. 2013 Mar; 28(3):277-83.
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  10. Wijtzes AI, Jansen W, Jaddoe VW, Moll HA, Tiemeier H, Verhulst FC, Hofman A, Mackenbach JP, Raat H. Ethnic background and television viewing time among 4-year-old preschool children: the generation R study. J Dev Behav Pediatr. 2013 Feb; 34(2):63-71.
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  11. White T, Marroun HE, Nijs I, Schmidt M, van der Lugt A, Wielopolki PA, Jaddoe VW, Hofman A, Krestin GP, Tiemeier H, Verhulst FC. Pediatric population-based neuroimaging and the Generation R Study: the intersection of developmental neuroscience and epidemiology. Eur J Epidemiol. 2013 Jan; 28(1):99-111.
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  12. Hruby A, Ngwa JS, Renström F, Wojczynski MK, Ganna A, Hallmans G, Houston DK, Jacques PF, Kanoni S, Lehtimäki T, Lemaitre RN, Manichaikul A, North KE, Ntalla I, Sonestedt E, Tanaka T, van Rooij FJ, Bandinelli S, Djoussé L, Grigoriou E, Johansson I, Lohman KK, Pankow JS, Raitakari OT, Riserus U, Yannakoulia M, Zillikens MC, Hassanali N, Liu Y, Mozaffarian D, Papoutsakis C, Syvänen AC, Uitterlinden AG, Viikari J, Groves CJ, Hofman A, Lind L, McCarthy MI, Mikkilä V, Mukamal K, Franco OH, Borecki IB, Cupples LA, Dedoussis GV, Ferrucci L, Hu FB, Ingelsson E, Kähönen M, Kao WH, Kritchevsky SB, Orho-Melander M, Prokopenko I, Rotter JI, Siscovick DS, Witteman JC, Franks PW, Meigs JB, McKeown NM, Nettleton JA. Higher Magnesium Intake Is Associated with Lower Fasting Glucose and Insulin, with No Evidence of Interaction with Select Genetic Loci, in a Meta-Analysis of 15 CHARGE Consortium Studies. J Nutr. 2013 Mar; 143(3):345-53.
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  13. Liamis G, Rodenburg EM, Hofman A, Zietse R, Stricker BH, Hoorn EJ. Electrolyte disorders in community subjects: prevalence and risk factors. Am J Med. 2013 Mar; 126(3):256-63.
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  14. Direk N, Schrijvers EM, de Bruijn RF, Mirza S, Hofman A, Ikram MA, Tiemeier H. Plasma amyloid ß, depression, and dementia in community-dwelling elderly. J Psychiatr Res. 2013 Apr; 47(4):479-85.
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  15. Perry JR, Corre T, Esko T, Chasman DI, Fischer K, Franceschini N, He C, Kutalik Z, Mangino M, Rose LM, Vernon Smith A, Stolk L, Sulem P, Weedon MN, Zhuang WV, Arnold A, Ashworth A, Bergmann S, Buring JE, Burri A, Chen C, Cornelis MC, Couper DJ, Goodarzi MO, Gudnason V, Harris T, Hofman A, Jones M, Kraft P, Launer L, Laven JS, Li G, McKnight B, Masciullo C, Milani L, Orr N, Psaty BM, Ridker PM, Rivadeneira F, Sala C, Salumets A, Schoemaker M, Traglia M, Waeber G, Chanock SJ, Demerath EW, Garcia M, Hankinson SE, Hu FB, Hunter DJ, Lunetta KL, Metspalu A, Montgomery GW, Murabito JM, Newman AB, Ong KK, Spector TD, Stefansson K, Swerdlow AJ, Thorsteinsdottir U, Van Dam RM, Uitterlinden AG, Visser JA, Vollenweider P, Toniolo D, Murray A. A genome-wide association study of early menopause and the combined impact of identified variants. Hum Mol Genet. 2013 Apr 1; 22(7):1465-72.
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  16. Kiefte-de Jong JC, Jaddoe VW, Uitterlinden AG, Steegers EA, Willemsen SP, Hofman A, Hooijkaas H, Moll HA. Levels of antibodies against tissue transglutaminase during pregnancy are associated with reduced fetal weight and birth weight. Gastroenterology. 2013 Apr; 144(4):726-735.e2.
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  17. Hek K, Demirkan A, Lahti J, Terracciano A, Teumer A, Cornelis MC, Amin N, Bakshis E, Baumert J, Ding J, Liu Y, Marciante K, Meirelles O, Nalls MA, Sun YV, Vogelzangs N, Yu L, Bandinelli S, Benjamin EJ, Bennett DA, Boomsma D, Cannas A, Coker LH, de Geus E, De Jager PL, Diez-Roux AV, Purcell S, Hu FB, Rimm EB, Hunter DJ, Jensen MK, Curhan G, Rice K, Penman AD, Rotter JI, Sotoodehnia N, Emeny R, Eriksson JG, Evans DA, Ferrucci L, Fornage M, Gudnason V, Hofman A, Illig T, Kardia S, Kelly-Hayes M, Koenen K, Kraft P, Kuningas M, Massaro JM, Melzer D, Mulas A, Mulder CL, Murray A, Oostra BA, Palotie A, Penninx B, Petersmann A, Pilling LC, Psaty B, Rawal R, Reiman EM, Schulz A, Shulman JM, Singleton AB, Smith AV, Sutin AR, Uitterlinden AG, Völzke H, Widen E, Yaffe K, Zonderman AB, Cucca F, Harris T, Ladwig KH, Llewellyn DJ, Räikkönen K, Tanaka T, van Duijn CM, Grabe HJ, Launer LJ, Lunetta KL, Mosley TH, Newman AB, Tiemeier H, Murabito J. A genome-wide association study of depressive symptoms. Biol Psychiatry. 2013 Apr 1; 73(7):667-78.
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  18. Altorf-van der Kuil W, Engberink MF, De Neve M, van Rooij FJ, Hofman A, Van't Veer P, Witteman JC, Franco OH, Geleijnse JM. Dietary amino acids and the risk of hypertension in a Dutch older population: the Rotterdam Study. Am J Clin Nutr. 2013 Feb; 97(2):403-10.
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  19. Rijlaarsdam J, Stevens GW, van der Ende J, Hofman A, Jaddoe VW, Mackenbach JP, Verhulst FC, Tiemeier H. Economic Disadvantage and Young Children's Emotional and Behavioral Problems: Mechanisms of Risk. J Abnorm Child Psychol. 2013 Jan; 41(1):125-37.
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  20. Ferket BS, van Kempen BJ, Heeringa J, Spronk S, Fleischmann KE, Nijhuis RL, Hofman A, Steyerberg EW, Hunink MG. Personalized prediction of lifetime benefits with statin therapy for asymptomatic individuals: a modeling study. PLoS Med. 2012 Dec; 9(12):e1001361.
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  21. Köttgen A, Albrecht E, Teumer A, Vitart V, Krumsiek J, Hundertmark C, Pistis G, Ruggiero D, O'Seaghdha CM, Haller T, Yang Q, Tanaka T, Johnson AD, Kutalik Z, Smith AV, Shi J, Struchalin M, Middelberg RP, Brown MJ, Gaffo AL, Pirastu N, Li G, Hayward C, Zemunik T, Huffman J, Yengo L, Zhao JH, Demirkan A, Feitosa MF, Liu X, Malerba G, Lopez LM, van der Harst P, Li X, Kleber ME, Hicks AA, Nolte IM, Johansson A, Murgia F, Wild SH, Bakker SJ, Peden JF, Dehghan A, Steri M, Tenesa A, Lagou V, Salo P, Mangino M, Rose LM, Lehtimäki T, Woodward OM, Okada Y, Tin A, Müller C, Oldmeadow C, Putku M, Czamara D, Kraft P, Frogheri L, Thun GA, Grotevendt A, Gislason GK, Harris TB, Launer LJ, McArdle P, Shuldiner AR, Boerwinkle E, Coresh J, Schmidt H, Schallert M, Martin NG, Montgomery GW, Kubo M, Nakamura Y, Tanaka T, Munroe PB, Samani NJ, Jacobs DR, Liu K, D'Adamo P, Ulivi S, Rotter JI, Psaty BM, Vollenweider P, Waeber G, Campbell S, Devuyst O, Navarro P, Kolcic I, Hastie N, Balkau B, Froguel P, Esko T, Salumets A, Khaw KT, Langenberg C, Wareham NJ, Isaacs A, Kraja A, Zhang Q, Wild PS, Scott RJ, Holliday EG, Org E, Viigimaa M, Bandinelli S, Metter JE, Lupo A, Trabetti E, Sorice R, Döring A, Lattka E, Strauch K, Theis F, Waldenberger M, Wichmann HE, Davies G, Gow AJ, Bruinenberg M, Stolk RP, Kooner JS, Zhang W, Winkelmann BR, Boehm BO, Lucae S, Penninx BW, Smit JH, Curhan G, Mudgal P, Plenge RM, Portas L, Persico I, Kirin M, Wilson JF, Mateo Leach I, van Gilst WH, Goel A, Ongen H, Hofman A, Rivadeneira F, Uitterlinden AG, Imboden M, von Eckardstein A, Cucca F, Nagaraja R, Piras MG, Nauck M, Schurmann C, Budde K, Ernst F, Farrington SM, Theodoratou E, Prokopenko I, Stumvoll M, Jula A, Perola M, Salomaa V, Shin SY, Spector TD, Sala C, Ridker PM, Kähönen M, Viikari J, Hengstenberg C, Nelson CP, Meschia JF, Nalls MA, Sharma P, Singleton AB, Kamatani N, Zeller T, Burnier M, Attia J, Laan M, Klopp N, Hillege HL, Kloiber S, Choi H, Pirastu M, Tore S, Probst-Hensch NM, Völzke H, Gudnason V, Parsa A, Schmidt R, Whitfield JB, Fornage M, Gasparini P, Siscovick DS, Polašek O, Campbell H, Rudan I, Bouatia-Naji N, Metspalu A, Loos RJ, van Duijn CM, Borecki IB, Ferrucci L, Gambaro G, Deary IJ, Wolffenbuttel BH, Chambers JC, März W, Pramstaller PP, Snieder H, Gyllensten U, Wright AF, Navis G, Watkins H, Witteman JC, Sanna S, Schipf S, Dunlop MG, Tönjes A, Ripatti S, Soranzo N, Toniolo D, Chasman DI, Raitakari O, Kao WH, Ciullo M, Fox CS, Caulfield M, Bochud M, Gieger C. Genome-wide association analyses identify 18 new loci associated with serum urate concentrations. Nat Genet. 2013 Feb; 45(2):145-54.
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  22. Snijder CA, Heederik D, Pierik FH, Hofman A, Jaddoe VW, Koch HM, Longnecker MP, Burdorf A. Fetal growth and prenatal exposure to bisphenol a: the generation R study. Environ Health Perspect. 2013 Mar; 121(3):393-8.
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  23. Hancock DB, Artigas MS, Gharib SA, Henry A, Manichaikul A, Ramasamy A, Loth DW, Imboden M, Koch B, McArdle WL, Smith AV, Smolonska J, Sood A, Tang W, Wilk JB, Zhai G, Zhao JH, Aschard H, Burkart KM, Curjuric I, Eijgelsheim M, Elliott P, Gu X, Harris TB, Janson C, Homuth G, Hysi PG, Liu JZ, Loehr LR, Lohman K, Loos RJ, Manning AK, Marciante KD, Obeidat M, Postma DS, Aldrich MC, Brusselle GG, Chen TH, Eiriksdottir G, Franceschini N, Heinrich J, Rotter JI, Wijmenga C, Williams OD, Bentley AR, Hofman A, Laurie CC, Lumley T, Morrison AC, Joubert BR, Rivadeneira F, Couper DJ, Kritchevsky SB, Liu Y, Wjst M, Wain LV, Vonk JM, Uitterlinden AG, Rochat T, Rich SS, Psaty BM, O'Connor GT, North KE, Mirel DB, Meibohm B, Launer LJ, Khaw KT, Hartikainen AL, Hammond CJ, Gläser S, Marchini J, Kraft P, Wareham NJ, Völzke H, Stricker BH, Spector TD, Probst-Hensch NM, Jarvis D, Jarvelin MR, Heckbert SR, Gudnason V, Boezen HM, Barr RG, Cassano PA, Strachan DP, Fornage M, Hall IP, Dupuis J, Tobin MD, London SJ. Genome-Wide Joint Meta-Analysis of SNP and SNP-by-Smoking Interaction Identifies Novel Loci for Pulmonary Function. PLoS Genet. 2012 Dec; 8(12):e1003098.
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  24. Flink IJ, Jansen PW, Beirens TM, Tiemeier H, van Ijzendoorn MH, Jaddoe VW, Hofman A, Raat H. Differences in problem behaviour among ethnic minority and majority preschoolers in the Netherlands and the role of family functioning and parenting factors as mediators: the Generation R Study. BMC Public Health. 2012; 12:1092.
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  25. Tharner A, Dierckx B, Luijk MP, van Ijzendoorn MH, Bakermans-Kranenburg MJ, van Ginkel JR, Moll HA, Jaddoe VW, Hofman A, Hudziak JJ, Verhulst FC, Tiemeier H. Attachment disorganization moderates the effect of maternal postnatal depressive symptoms on infant autonomic functioning. Psychophysiology. 2013 Feb; 50(2):195-203.
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  26. Bos D, Ikram MA, Isaacs A, Verhaaren BF, Hofman A, van Duijn CM, Witteman JC, van der Lugt A, Vernooij MW. Genetic Loci for coronary calcification and serum lipids relate to aortic and carotid calcification. Circ Cardiovasc Genet. 2013 Feb 1; 6(1):47-53.
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  27. Singaraja RR, Sivapalaratnam S, Hovingh K, Dubé MP, Castro-Perez J, Collins HL, Adelman SJ, Riwanto M, Manz J, Hubbard B, Tietjen I, Wong K, Mitnaul LJ, van Heek M, Lin L, Roddy TA, McEwen J, Dallinge-Thie G, van Vark-van der Zee L, Verwoert G, Winther M, van Duijn C, Hofman A, Trip MD, Marais AD, Asztalos B, Landmesser U, Sijbrands E, Kastelein JJ, Hayden MR. The Impact of Partial and Complete Loss-of-Function Mutations in Endothelial Lipase on High-Density Lipoprotein Levels and Functionality in Humans. Circ Cardiovasc Genet. 2013 Feb 1; 6(1):54-62.
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  28. Richardson K, Nettleton JA, Rotllan N, Tanaka T, Smith CE, Lai CQ, Parnell LD, Lee YC, Lahti J, Lemaitre RN, Manichaikul A, Keller M, Mikkilä V, Ngwa J, van Rooij FJ, Ballentyne CM, Borecki IB, Cupples LA, Garcia M, Hofman A, Ferrucci L, Mozaffarian D, Perälä MM, Raitakari O, Tracy RP, Arnett DK, Bandinelli S, Boerwinkle E, Eriksson JG, Franco OH, Kähönen M, Nalls M, Siscovick DS, Houston DK, Psaty BM, Viikari J, Witteman JC, Goodarzi MO, Lehtimäki T, Liu Y, Zillikens MC, Chen YD, Uitterlinden AG, Rotter JI, Fernandez-Hernando C, Ordovas JM. Gain-of-Function Lipoprotein Lipase Variant rs13702 Modulates Lipid Traits through Disruption of a MicroRNA-410 Seed Site. Am J Hum Genet. 2013 Jan 10; 92(1):5-14.
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  29. Sonnenschein-van der Voort AM, de Kluizenaar Y, Jaddoe VW, Gabriele C, Raat H, Moll HA, Hofman A, Pierik FH, Miedema HM, de Jongste JC, Duijts L. Air pollution, fetal and infant tobacco smoke exposure, and wheezing in preschool children: a population-based prospective birth cohort. Environ Health. 2012; 11:91.
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  30. van Kempen BJ, Ferket BS, Hofman A, Steyerberg EW, Colkesen EB, Boekholdt SM, Wareham NJ, Khaw KT, Hunink MM. Validation of a model to investigate the effects of modifying cardiovascular disease (CVD) risk factors on the burden of CVD: the rotterdam ischemic heart disease and stroke computer simulation (RISC) model. BMC Med. 2012; 10:158.
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  31. Selwaness M, van den Bouwhuijsen QJ, Verwoert GC, Dehghan A, Mattace-Raso FU, Vernooij M, Franco OH, Hofman A, van der Lugt A, Wentzel JJ, Witteman JC. Blood pressure parameters and carotid intraplaque hemorrhage as measured by magnetic resonance imaging: the rotterdam study. Hypertension. 2013 Jan; 61(1):76-81.
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  34. Velders FP, De Wit JE, Jansen PW, Jaddoe VW, Hofman A, Verhulst FC, Tiemeier H. FTO at rs9939609, Food Responsiveness, Emotional Control and Symptoms of ADHD in Preschool Children. PLoS One. 2012; 7(11):e49131.
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  35. Jonsson T, Stefansson H, Steinberg S, Jonsdottir I, Jonsson PV, Snaedal J, Bjornsson S, Huttenlocher J, Levey AI, Lah JJ, Rujescu D, Hampel H, Giegling I, Andreassen OA, Engedal K, Ulstein I, Djurovic S, Ibrahim-Verbaas C, Hofman A, Ikram MA, van Duijn CM, Thorsteinsdottir U, Kong A, Stefansson K. Variant of TREM2 associated with the risk of Alzheimer's disease. N Engl J Med. 2013 Jan 10; 368(2):107-16.
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  36. Saavedra Perez HC, Direk N, Hofman A, Vernooij MW, Tiemeier H, Ikram MA. Silent brain infarcts: A cause of depression in the elderly? Psychiatry Res. 2013 Feb 28; 211(2):180-2.
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  37. Medici M, Timmermans S, Visser W, de Muinck Keizer-Schrama SM, Jaddoe VW, Hofman A, Hooijkaas H, de Rijke YB, Tiemeier H, Bongers-Schokking JJ, Visser TJ, Peeters RP, Steegers EA. Maternal Thyroid Hormone Parameters during Early Pregnancy and Birth Weight: The Generation R Study. J Clin Endocrinol Metab. 2013 Jan; 98(1):59-66.
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  38. Kiefte-de Jong JC, de Vries JH, Franco OH, Jaddoe VW, Hofman A, Raat H, de Jongste JC, Moll HA. Fish Consumption in Infancy and Asthma-like Symptoms at Preschool Age. Pediatrics. 2012 Dec; 130(6):1060-8.
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  39. Lahousse L, van den Bouwhuijsen QJ, Loth DW, Joos GF, Hofman A, Witteman JC, van der Lugt A, Brusselle GG, Stricker BH. Chronic obstructive pulmonary disease and lipid core carotid artery plaques in the elderly: the rotterdam study. Am J Respir Crit Care Med. 2013 Jan 1; 187(1):58-64.
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  40. Heppe DH, Kiefte-de Jong JC, Durmus B, Moll HA, Raat H, Hofman A, Jaddoe VW. Parental, fetal, and infant risk factors for preschool overweight: the Generation R Study. Pediatr Res. 2013 Jan; 73(1):120-7.
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  41. Lahousse L, Loth DW, Joos GF, Hofman A, Leufkens HG, Brusselle GG, Stricker BH. Statins, systemic inflammation and risk of death in COPD: The Rotterdam study. Pulm Pharmacol Ther. 2013 Apr; 26(2):212-7.
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  42. Jansen PW, Roza SJ, Jaddoe VW, Mackenbach JD, Raat H, Hofman A, Verhulst FC, Tiemeier H. Children's eating behavior, feeding practices of parents and weight problems in early childhood: results from the population-based Generation R Study. Int J Behav Nutr Phys Act. 2012; 9:130.
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  44. Medici M, Ikram MA, van der Lijn F, Heijer Td, Vernooij MW, Hofman A, Niessen WJ, Visser TJ, Breteler MM, Peeters RP. The Thyroid Hormone Receptor Alpha Locus and White Matter Lesions: A Role for the Clock Gene REV-ERBa. Thyroid. 2012 Nov; 22(11):1181-6.
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  46. Jacobs LC, Wollstein A, Lao O, Hofman A, Klaver CC, Uitterlinden AG, Nijsten T, Kayser M, Liu F. Comprehensive candidate gene study highlights UGT1A and BNC2 as new genes determining continuous skin color variation in Europeans. Hum Genet. 2013 Feb; 132(2):147-58.
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  51. Verlinden M, Tiemeier H, Hudziak JJ, Jaddoe VW, Raat H, Guxens M, Hofman A, Verhulst FC, Jansen PW. Television viewing and externalizing problems in preschool children: the Generation R Study. Arch Pediatr Adolesc Med. 2012 Oct; 166(10):919-25.
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  55. Huang J, Sabater-Lleal M, Asselbergs FW, Tregouet D, Shin SY, Ding J, Baumert J, Oudot-Mellakh T, Folkersen L, Johnson AD, Smith NL, Williams SM, Ikram MA, Kleber ME, Becker DM, Truong V, Mychaleckyj JC, Tang W, Yang Q, Sennblad B, Moore JH, Williams FM, Dehghan A, Silbernagel G, Schrijvers EM, Smith S, Karakas M, Tofler GH, Silveira A, Navis GJ, Lohman K, Chen MH, Peters A, Goel A, Hopewell JC, Chambers JC, Saleheen D, Lundmark P, Psaty BM, Strawbridge RJ, Boehm BO, Carter AM, Meisinger C, Peden JF, Bis JC, McKnight B, Ohrvik J, Taylor K, Franzosi MG, Seedorf U, Collins R, Franco-Cereceda A, Syvänen AC, Goodall AH, Yanek LR, Cushman M, Müller-Nurasyid M, Folsom AR, Basu S, Matijevic N, van Gilst WH, Kooner JS, Hofman A, Danesh J, Clarke R, Meigs JB, Kathiresan S, Reilly MP, Klopp N, Harris TB, Winkelmann BR, Grant PJ, Hillege HL, Watkins H, Spector TD, Becker LC, Tracy RP, März W, Uitterlinden AG, Eriksson P, Cambien F, Morange PE, Koenig W, Soranzo N, van der Harst P, Liu Y, O'Donnell CJ, Hamsten A. Genome-wide association study for circulating levels of PAI-1 provides novel insights into its regulation. Blood. 2012 Dec 6; 120(24):4873-81.
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  64. Leening MJ, Elias-Smale SE, Kavousi M, Felix JF, Deckers JW, Vliegenthart R, Oudkerk M, Hofman A, Steyerberg EW, Stricker BH, Witteman JC. Coronary calcification and the risk of heart failure in the elderly: the Rotterdam Study. JACC Cardiovasc Imaging. 2012 Sep; 5(9):874-80.
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  65. Choté A, de Groot C, Redekop K, Hoefman R, Koopmans G, Jaddoe V, Hofman A, Steegers E, Trappenburg M, Mackenbach J, Foets M. Differences in quality of antenatal care provided by midwives to low-risk pregnant dutch women in different ethnic groups. J Midwifery Womens Health. 2012 Sep-Oct; 57(5):461-8.
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  66. Ghassabian A, Herba CM, Roza SJ, Govaert P, Schenk JJ, Jaddoe VW, Hofman A, White T, Verhulst FC, Tiemeier H. Infant brain structures, executive function, and attention deficit/hyperactivity problems at preschool age. A prospective study. J Child Psychol Psychiatry. 2013 Jan; 54(1):96-104.
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  67. van den Hooven EH, Pierik FH, de Kluizenaar Y, Hofman A, van Ratingen SW, Zandveld PY, Russcher H, Lindemans J, Miedema HM, Steegers EA, Jaddoe VW. Air pollution exposure and markers of placental growth and function: the generation R study. Environ Health Perspect. 2012 Dec; 120(12):1753-9.
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  68. Poels MM, Steyerberg EW, Wieberdink RG, Hofman A, Koudstaal PJ, Ikram MA, Breteler MM. Assessment of cerebral small vessel disease predicts individual stroke risk. J Neurol Neurosurg Psychiatry. 2012 Dec; 83(12):1174-9.
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  69. Den Ruijter HM, Peters SA, Anderson TJ, Britton AR, Dekker JM, Eijkemans MJ, Engström G, Evans GW, de Graaf J, Grobbee DE, Hedblad B, Hofman A, Holewijn S, Ikeda A, Kavousi M, Kitagawa K, Kitamura A, Koffijberg H, Lonn EM, Lorenz MW, Mathiesen EB, Nijpels G, Okazaki S, O'Leary DH, Polak JF, Price JF, Robertson C, Rembold CM, Rosvall M, Rundek T, Salonen JT, Sitzer M, Stehouwer CD, Witteman JC, Moons KG, Bots ML. Common carotid intima-media thickness measurements in cardiovascular risk prediction: a meta-analysis. JAMA. 2012 Aug 22; 308(8):796-803.
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  70. Sikorska K, Rivadeneira F, Groenen PJ, Hofman A, Uitterlinden AG, Eilers PH, Lesaffre E. Fast linear mixed model computations for genome-wide association studies with longitudinal data. Stat Med. 2013 Jan 15; 32(1):165-80.
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  74. van Mil NH, Steegers-Theunissen RP, Bongers-Schokking JJ, Marroun HE, Ghassabian A, Hofman A, Jaddoe VW, Visser TJ, Verhulst FC, de Rijke YB, Steegers EA, Tiemeier H. Maternal hypothyroxinemia during pregnancy and growth of the fetal and infant head. Reprod Sci. 2012 Dec; 19(12):1315-22.
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  75. Poels MM, Zaccai K, Verwoert GC, Vernooij MW, Hofman A, van der Lugt A, Witteman JC, Breteler MM, Mattace-Raso FU, Ikram MA. Arterial stiffness and cerebral small vessel disease: the Rotterdam Scan Study. Stroke. 2012 Oct; 43(10):2637-42.
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  77. Koehler EM, Schouten JN, Hansen BE, van Rooij FJ, Hofman A, Stricker BH, Janssen HL. Prevalence and risk factors of non-alcoholic fatty liver disease in the elderly: Results from the Rotterdam study. J Hepatol. 2012 Dec; 57(6):1305-11.
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  78. van Schie RM, el Khedr N, Verhoef TI, Teichert M, Stricker BH, Hofman A, Buhre PN, Wessels JA, Schalekamp T, le Cessie S, van der Meer FJ, Rosendaal FR, de Boer A, Maitland-van der Zee AH, Visser LE. Validation of the acenocoumarol EU-PACT algorithms: similar performance in the Rotterdam Study cohort as in the original study. Pharmacogenomics. 2012 Aug; 13(11):1239-45.
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  79. Rijlaarsdam J, Stevens GW, van der Ende J, Arends LR, Hofman A, Jaddoe VW, Mackenbach JP, Verhulst FC, Tiemeier H. A brief observational instrument for the assessment of infant home environment: development and psychometric testing. Int J Methods Psychiatr Res. 2012 Sep; 21(3):195-204.
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  82. Mook-Kanamori DO, van Beijsterveldt CE, Steegers EA, Aulchenko YS, Raat H, Hofman A, Eilers PH, Boomsma DI, Jaddoe VW. Heritability estimates of body size in fetal life and early childhood. PLoS One. 2012; 7(7):e39901.
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  83. McQuillan R, Eklund N, Pirastu N, Kuningas M, McEvoy BP, Esko T, Corre T, Davies G, Kaakinen M, Lyytikäinen LP, Kristiansson K, Havulinna AS, Gögele M, Vitart V, Tenesa A, Aulchenko Y, Hayward C, Johansson A, Boban M, Ulivi S, Robino A, Boraska V, Igl W, Wild SH, Zgaga L, Amin N, Theodoratou E, Polašek O, Girotto G, Lopez LM, Sala C, Lahti J, Laatikainen T, Prokopenko I, Kals M, Viikari J, Yang J, Pouta A, Estrada K, Hofman A, Freimer N, Martin NG, Kähönen M, Milani L, Heliövaara M, Vartiainen E, Räikkönen K, Masciullo C, Starr JM, Hicks AA, Esposito L, Kolcic I, Farrington SM, Oostra B, Zemunik T, Campbell H, Kirin M, Pehlic M, Faletra F, Porteous D, Pistis G, Widén E, Salomaa V, Koskinen S, Fischer K, Lehtimäki T, Heath A, McCarthy MI, Rivadeneira F, Montgomery GW, Tiemeier H, Hartikainen AL, Madden PA, d'Adamo P, Hastie ND, Gyllensten U, Wright AF, van Duijn CM, Dunlop M, Rudan I, Gasparini P, Pramstaller PP, Deary IJ, Toniolo D, Eriksson JG, Jula A, Raitakari OT, Metspalu A, Perola M, Järvelin MR, Uitterlinden A, Visscher PM, Wilson JF. Evidence of inbreeding depression on human height. PLoS Genet. 2012; 8(7):e1002655.
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  85. Hafkamp-de Groen E, Mohangoo AD, Landgraf JM, de Jongste JC, Duijts L, Moll HA, Jaddoe VW, Hofman A, Raat H. The impact of preschool wheezing patterns on health-related quality of life at age 4 years. Eur Respir J. 2013 Apr; 41(4):952-9.
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  86. Velders FP, Dieleman G, Cents RA, Bakermans-Kranenburg MJ, Jaddoe VW, Hofman A, Van Ijzendoorn MH, Verhulst FC, Tiemeier H. Variation in the glucocorticoid receptor gene at rs41423247 moderates the effect of prenatal maternal psychological symptoms on child cortisol reactivity and behavior. Neuropsychopharmacology. 2012 Oct; 37(11):2541-9.
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  87. Schrijvers EM, Buitendijk GH, Ikram MK, Koudstaal PJ, Hofman A, Vingerling JR, Breteler MM. Retinopathy and risk of dementia: the Rotterdam Study. Neurology. 2012 Jul 24; 79(4):365-70.
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  88. Hek K, Direk N, Newson RS, Hofman A, Hoogendijk WJ, Mulder CL, Tiemeier H. Anxiety disorders and salivary cortisol levels in older adults: a population-based study. Psychoneuroendocrinology. 2013 Feb; 38(2):300-5.
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  89. Medina-Gomez C, Kemp JP, Estrada K, Eriksson J, Liu J, Reppe S, Evans DM, Heppe DH, Vandenput L, Herrera L, Ring SM, Kruithof CJ, Timpson NJ, Zillikens MC, Olstad OK, Zheng HF, Richards JB, St Pourcain B, Hofman A, Jaddoe VW, Smith GD, Lorentzon M, Gautvik KM, Uitterlinden AG, Brommage R, Ohlsson C, Tobias JH, Rivadeneira F. Meta-analysis of genome-wide scans for total body BMD in children and adults reveals allelic heterogeneity and age-specific effects at the WNT16 locus. PLoS Genet. 2012 Jul; 8(7):e1002718.
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  90. Rijlaarsdam J, Tiemeier H, Hofman A, Jaddoe VW, Mackenbach JP, Verhulst FC, Stevens GW. Home environments of infants: relations with child development through age 3. J Epidemiol Community Health. 2013 Jan; 67(1):14-20.
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  91. El Marroun H, Jaddoe VW, Hudziak JJ, Roza SJ, Steegers EA, Hofman A, Verhulst FC, White TJ, Stricker BH, Tiemeier H. Maternal use of selective serotonin reuptake inhibitors, fetal growth, and risk of adverse birth outcomes. Arch Gen Psychiatry. 2012 Jul; 69(7):706-14.
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  93. Snijder CA, Brand T, Jaddoe V, Hofman A, Mackenbach JP, Steegers EA, Burdorf A. Physically demanding work, fetal growth and the risk of adverse birth outcomes. The Generation R Study. Occup Environ Med. 2012 Aug; 69(8):543-50.
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  94. Marcus MW, Müskens RP, Ramdas WD, Wolfs RC, de Jong PT, Vingerling JR, Hofman A, Stricker BH, Jansonius NM. Antithrombotic medication and incident open-angle glaucoma. Invest Ophthalmol Vis Sci. 2012 Jun; 53(7):3801-5.
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  95. Nugteren JJ, Snijder CA, Hofman A, Jaddoe VW, Steegers EA, Burdorf A. Work-related maternal risk factors and the risk of pregnancy induced hypertension and preeclampsia during pregnancy. The Generation R Study. PLoS One. 2012; 7(6):e39263.
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  96. Durik M, Kavousi M, van der Pluijm I, Isaacs A, Cheng C, Verdonk K, Loot AE, Oeseburg H, Bhaggoe UM, Leijten F, van Veghel R, de Vries R, Rudez G, Brandt R, Ridwan YR, van Deel ED, de Boer M, Tempel D, Fleming I, Mitchell GF, Verwoert GC, Tarasov KV, Uitterlinden AG, Hofman A, Duckers HJ, van Duijn CM, Oostra BA, Witteman JC, Duncker DJ, Danser AH, Hoeijmakers JH, Roks AJ. Nucleotide excision DNA repair is associated with age-related vascular dysfunction. Circulation. 2012 Jul 24; 126(4):468-78.
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  99. Tharner A, Luijk MP, Raat H, Ijzendoorn MH, Bakermans-Kranenburg MJ, Moll HA, Jaddoe VW, Hofman A, Verhulst FC, Tiemeier H. Breastfeeding and its relation to maternal sensitivity and infant attachment. J Dev Behav Pediatr. 2012 Jun; 33(5):396-404.
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  100. Coolman M, Timmermans S, de Groot CJ, Russcher H, Lindemans J, Hofman A, Geurts-Moespot AJ, Sweep FC, Jaddoe VV, Steegers EA. Angiogenic and fibrinolytic factors in blood during the first half of pregnancy and adverse pregnancy outcomes. Obstet Gynecol. 2012 Jun; 119(6):1190-200.
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  102. Perry JR, Voight BF, Yengo L, Amin N, Dupuis J, Ganser M, Grallert H, Navarro P, Li M, Qi L, Steinthorsdottir V, Scott RA, Almgren P, Arking DE, Aulchenko Y, Balkau B, Benediktsson R, Bergman RN, Boerwinkle E, Bonnycastle L, Burtt NP, Campbell H, Charpentier G, Collins FS, Gieger C, Green T, Hadjadj S, Hattersley AT, Herder C, Hofman A, Johnson AD, Kottgen A, Kraft P, Labrune Y, Langenberg C, Manning AK, Mohlke KL, Morris AP, Oostra B, Pankow J, Petersen AK, Pramstaller PP, Prokopenko I, Rathmann W, Rayner W, Roden M, Rudan I, Rybin D, Scott LJ, Sigurdsson G, Sladek R, Thorleifsson G, Thorsteinsdottir U, Tuomilehto J, Uitterlinden AG, Vivequin S, Weedon MN, Wright AF, Hu FB, Illig T, Kao L, Meigs JB, Wilson JF, Stefansson K, van Duijn C, Altschuler D, Morris AD, Boehnke M, McCarthy MI, Froguel P, Palmer CN, Wareham NJ, Groop L, Frayling TM, Cauchi S. Stratifying type 2 diabetes cases by BMI identifies genetic risk variants in LAMA1 and enrichment for risk variants in lean compared to obese cases. PLoS Genet. 2012 May; 8(5):e1002741.
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  103. Rodenburg EM, Eijgelsheim M, Geleijnse JM, Amin N, van Duijn CM, Hofman A, Uitterlinden AG, Stricker BH, Visser LE. CYP1A2 and coffee intake and the modifying effect of sex, age, and smoking. Am J Clin Nutr. 2012 Jul; 96(1):182-7.
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  104. Silva LM, van Rossem L, Jansen PW, Hokken-Koelega AC, Moll HA, Hofman A, Mackenbach JP, Jaddoe VW, Raat H. Children of low socioeconomic status show accelerated linear growth in early childhood; results from the Generation R Study. PLoS One. 2012; 7(5):e37356.
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  105. Bouthoorn SH, Gaillard R, Steegers EA, Hofman A, Jaddoe VW, van Lenthe FJ, Raat H. Ethnic differences in blood pressure and hypertensive complications during pregnancy: the Generation R study. Hypertension. 2012 Jul; 60(1):198-205.
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  106. van Woudenbergh GJ, Kuijsten A, Tigcheler B, Sijbrands EJ, van Rooij FJ, Hofman A, Witteman JC, Feskens EJ. Meat consumption and its association with C-reactive protein and incident type 2 diabetes: the Rotterdam Study. Diabetes Care. 2012 Jul; 35(7):1499-505.
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  109. Flink IJ, Beirens TM, Looman C, Landgraf JM, Tiemeier H, Mol HA, Jaddoe VW, Hofman A, Mackenbach JP, Raat H. Health-related quality of life of infants from ethnic minority groups: the Generation R Study. Qual Life Res. 2013 Apr; 22(3):653-64.
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  110. Steenweg-de Graaff J, Roza SJ, Steegers EA, Hofman A, Verhulst FC, Jaddoe VW, Tiemeier H. Maternal folate status in early pregnancy and child emotional and behavioral problems: the Generation R Study. Am J Clin Nutr. 2012 Jun; 95(6):1413-21.
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  111. Bos D, van der Rijk MJ, Geeraedts TE, Hofman A, Krestin GP, Witteman JC, van der Lugt A, Ikram MA, Vernooij MW. Intracranial carotid artery atherosclerosis: prevalence and risk factors in the general population. Stroke. 2012 Jul; 43(7):1878-84.
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  112. Castaño Betancourt MC, Cailotto F, Kerkhof HJ, Cornelis FM, Doherty SA, Hart DJ, Hofman A, Luyten FP, Maciewicz RA, Mangino M, Metrustry S, Muir K, Peters MJ, Rivadeneira F, Wheeler M, Zhang W, Arden N, Spector TD, Uitterlinden AG, Doherty M, Lories RJ, Valdes AM, van Meurs JB. Genome-wide association and functional studies identify the DOT1L gene to be involved in cartilage thickness and hip osteoarthritis. Proc Natl Acad Sci U S A. 2012 May 22; 109(21):8218-23.
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  113. Hoeven TA, Kavousi M, Clockaerts S, Kerkhof HJ, van Meurs JB, Franco O, Hofman A, Bindels P, Witteman J, Bierma-Zeinstra S. Association of atherosclerosis with presence and progression of osteoarthritis: the Rotterdam Study. Ann Rheum Dis. 2013 May; 72(5):646-51.
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  114. van Koolwijk LM, Ramdas WD, Ikram MK, Jansonius NM, Pasutto F, Hysi PG, Macgregor S, Janssen SF, Hewitt AW, Viswanathan AC, ten Brink JB, Hosseini SM, Amin N, Despriet DD, Willemse-Assink JJ, Kramer R, Rivadeneira F, Struchalin M, Aulchenko YS, Weisschuh N, Zenkel M, Mardin CY, Gramer E, Welge-Lüssen U, Montgomery GW, Carbonaro F, Young TL, Bellenguez C, McGuffin P, Foster PJ, Topouzis F, Mitchell P, Wang JJ, Wong TY, Czudowska MA, Hofman A, Uitterlinden AG, Wolfs RC, de Jong PT, Oostra BA, Paterson AD, Mackey DA, Bergen AA, Reis A, Hammond CJ, Vingerling JR, Lemij HG, Klaver CC, van Duijn CM. Common genetic determinants of intraocular pressure and primary open-angle glaucoma. PLoS Genet. 2012; 8(5):e1002611.
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  115. Engberink MF, Bakker SJ, Brink EJ, van Baak MA, van Rooij FJ, Hofman A, Witteman JC, Geleijnse JM. Dietary acid load and risk of hypertension: the Rotterdam Study. Am J Clin Nutr. 2012 Jun; 95(6):1438-44.
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  116. El Marroun H, Zeegers M, Steegers EA, van der Ende J, Schenk JJ, Hofman A, Jaddoe VW, Verhulst FC, Tiemeier H. Post-term birth and the risk of behavioural and emotional problems in early childhood. Int J Epidemiol. 2012 Jun; 41(3):773-81.
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  117. Bradfield JP, Taal HR, Timpson NJ, Scherag A, Lecoeur C, Warrington NM, Hypponen E, Holst C, Valcarcel B, Thiering E, Salem RM, Schumacher FR, Cousminer DL, Sleiman PM, Zhao J, Berkowitz RI, Vimaleswaran KS, Jarick I, Pennell CE, Evans DM, St Pourcain B, Berry DJ, Mook-Kanamori DO, Hofman A, Rivadeneira F, Uitterlinden AG, van Duijn CM, van der Valk RJ, de Jongste JC, Postma DS, Boomsma DI, Gauderman WJ, Hassanein MT, Lindgren CM, Mägi R, Boreham CA, Neville CE, Moreno LA, Elliott P, Pouta A, Hartikainen AL, Li M, Raitakari O, Lehtimäki T, Eriksson JG, Palotie A, Dallongeville J, Das S, Deloukas P, McMahon G, Ring SM, Kemp JP, Buxton JL, Blakemore AI, Bustamante M, Guxens M, Hirschhorn JN, Gillman MW, Kreiner-Møller E, Bisgaard H, Gilliland FD, Heinrich J, Wheeler E, Barroso I, O'Rahilly S, Meirhaeghe A, Sørensen TI, Power C, Palmer LJ, Hinney A, Widen E, Farooqi IS, McCarthy MI, Froguel P, Meyre D, Hebebrand J, Jarvelin MR, Jaddoe VW, Smith GD, Hakonarson H, Grant SF. A genome-wide association meta-analysis identifies new childhood obesity loci. Nat Genet. 2012 May; 44(5):526-31.
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  119. Bos D, Vernooij MW, Elias-Smale SE, Verhaaren BF, Vrooman HA, Hofman A, Niessen WJ, Witteman JC, van der Lugt A, Ikram MA. Atherosclerotic calcification relates to cognitive function and to brain changes on magnetic resonance imaging. Alzheimers Dement. 2012 Oct; 8(5 Suppl):S104-11.
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  120. Ikram MA, Fornage M, Smith AV, Seshadri S, Schmidt R, Debette S, Vrooman HA, Sigurdsson S, Ropele S, Taal HR, Mook-Kanamori DO, Coker LH, Longstreth WT, Niessen WJ, DeStefano AL, Beiser A, Zijdenbos AP, Struchalin M, Jack CR, Rivadeneira F, Uitterlinden AG, Knopman DS, Hartikainen AL, Pennell CE, Thiering E, Steegers EA, Hakonarson H, Heinrich J, Palmer LJ, Jarvelin MR, McCarthy MI, Grant SF, St Pourcain B, Timpson NJ, Smith GD, Sovio U, Nalls MA, Au R, Hofman A, Gudnason H, van der Lugt A, Harris TB, Meeks WM, Vernooij MW, van Buchem MA, Catellier D, Jaddoe VW, Gudnason V, Windham BG, Wolf PA, van Duijn CM, Mosley TH, Schmidt H, Launer LJ, Breteler MM, DeCarli C. Common variants at 6q22 and 17q21 are associated with intracranial volume. Nat Genet. 2012 May; 44(5):539-44.
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  124. Diekstra FP, Saris CG, van Rheenen W, Franke L, Jansen RC, van Es MA, van Vught PW, Blauw HM, Groen EJ, Horvath S, Estrada K, Rivadeneira F, Hofman A, Uitterlinden AG, Robberecht W, Andersen PM, Melki J, Meininger V, Hardiman O, Landers JE, Brown RH, Shatunov A, Shaw CE, Leigh PN, Al-Chalabi A, Ophoff RA, van den Berg LH, Veldink JH. Mapping of gene expression reveals CYP27A1 as a susceptibility gene for sporadic ALS. PLoS One. 2012; 7(4):e35333.
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  125. Mühleisen TW, Mattheisen M, Strohmaier J, Degenhardt F, Priebe L, Schultz CC, Breuer R, Meier S, Hoffmann P, Rivandeneira F, Hofman A, Uitterlinden AG, Moebus S, Gieger C, Emeny R, Ladwig KH, Wichmann HE, Schwarz M, Kammerer-Ciernioch J, Schlösser RG, Nenadic I, Sauer H, Mössner R, Maier W, Rujescu D, Lange C, Ophoff RA, Schulze TG, Rietschel M, Nöthen MM, Cichon S. Association between schizophrenia and common variation in neurocan (NCAN), a genetic risk factor for bipolar disorder. Schizophr Res. 2012 Jun; 138(1):69-73.
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  126. Rossem Lv, Kiefte-de Jong JC, Looman CW, Jaddoe VW, Hofman A, Hokken-Koelega AC, Mackenbach JP, Moll HA, Raat H. Weight change before and after the introduction of solids: results from a longitudinal birth cohort. Br J Nutr. 2013 Jan; 109(2):370-5.
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  127. Kiefte-de Jong JC, de Vries JH, Bleeker SE, Jaddoe VW, Hofman A, Raat H, Moll HA. Socio-demographic and lifestyle determinants of 'Western-like' and 'Health conscious' dietary patterns in toddlers. Br J Nutr. 2013 Jan; 109(1):137-47.
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  128. Gabriele C, Silva LM, Arends LR, Raat H, Moll HA, Hofman A, Jaddoe VW, de Jongste JC. Early respiratory morbidity in a multicultural birth cohort: the Generation R Study. Eur J Epidemiol. 2012 Jun; 27(6):453-62.
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  129. Leermakers ET, Taal HR, Bakker R, Steegers EA, Hofman A, Jaddoe VW. A Common Genetic Variant at 15q25 Modifies the Associations of Maternal Smoking during Pregnancy with Fetal Growth: The Generation R Study. PLoS One. 2012; 7(4):e34584.
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  130. van Kempen BJ, Ferket BS, Hofman A, Spronk S, Steyerberg E, Hunink MG. Do different methods of modeling statin treatment effectiveness influence the optimal decision? Med Decis Making. 2012 May-Jun; 32(3):507-16.
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  131. Ramdas WD, Wolfs RC, Kiefte-de Jong JC, Hofman A, de Jong PT, Vingerling JR, Jansonius NM. Nutrient intake and risk of open-angle glaucoma: the Rotterdam Study. Eur J Epidemiol. 2012 May; 27(5):385-93.
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  140. Wieberdink RG, Ikram MA, Hofman A, Koudstaal PJ, Breteler MM. Trends in stroke incidence rates and stroke risk factors in Rotterdam, the Netherlands from 1990 to 2008. Eur J Epidemiol. 2012 Apr; 27(4):287-95.
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  142. Kiefte-de Jong JC, Timmermans S, Jaddoe VW, Hofman A, Tiemeier H, Steegers EA, de Jongste JC, Moll HA. High circulating folate and vitamin B-12 concentrations in women during pregnancy are associated with increased prevalence of atopic dermatitis in their offspring. J Nutr. 2012 Apr; 142(4):731-8.
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  143. Leening MJ, Kavousi M, Heeringa J, van Rooij FJ, Verkroost-van Heemst J, Deckers JW, Mattace-Raso FU, Ziere G, Hofman A, Stricker BH, Witteman JC. Methods of data collection and definitions of cardiac outcomes in the Rotterdam Study. Eur J Epidemiol. 2012 Mar; 27(3):173-85.
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  144. Direk N, Koudstaal PJ, Hofman A, Ikram MA, Hoogendijk WJ, Tiemeier H. Cerebral hemodynamics and incident depression: the Rotterdam Study. Biol Psychiatry. 2012 Aug 15; 72(4):318-23.
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  146. Van den Hooven EH, Pierik FH, Van Ratingen SW, Zandveld PY, Meijer EW, Hofman A, Miedema HM, Jaddoe VW, De Kluizenaar Y. Air pollution exposure estimation using dispersion modelling and continuous monitoring data in a prospective birth cohort study in The Netherlands. Environ Health. 2012; 11:9.
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  147. Timmermans S, Steegers-Theunissen RP, Vujkovic M, den Breeijen H, Russcher H, Lindemans J, Mackenbach J, Hofman A, Lesaffre EE, Jaddoe VV, Steegers EA. The Mediterranean diet and fetal size parameters: the Generation R Study. Br J Nutr. 2012 Oct; 108(8):1399-409.
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  148. Walter S, Mackenbach J, Vokó Z, Lhachimi S, Ikram MA, Uitterlinden AG, Newman AB, Murabito JM, Garcia ME, Gudnason V, Tanaka T, Tranah GJ, Wallaschofski H, Kocher T, Launer LJ, Franceschini N, Schipper M, Hofman A, Tiemeier H. Genetic, physiological, and lifestyle predictors of mortality in the general population. Am J Public Health. 2012 Apr; 102(4):e3-10.
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  149. Demirkan A, van Duijn CM, Ugocsai P, Isaacs A, Pramstaller PP, Liebisch G, Wilson JF, Johansson Å, Rudan I, Aulchenko YS, Kirichenko AV, Janssens AC, Jansen RC, Gnewuch C, Domingues FS, Pattaro C, Wild SH, Jonasson I, Polasek O, Zorkoltseva IV, Hofman A, Karssen LC, Struchalin M, Floyd J, Igl W, Biloglav Z, Broer L, Pfeufer A, Pichler I, Campbell S, Zaboli G, Kolcic I, Rivadeneira F, Huffman J, Hastie ND, Uitterlinden A, Franke L, Franklin CS, Vitart V, Nelson CP, Preuss M, Bis JC, O'Donnell CJ, Franceschini N, Witteman JC, Axenovich T, Oostra BA, Meitinger T, Hicks AA, Hayward C, Wright AF, Gyllensten U, Campbell H, Schmitz G. Genome-wide association study identifies novel loci associated with circulating phospho- and sphingolipid concentrations. PLoS Genet. 2012; 8(2):e1002490.
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  150. Alssema M, Newson RS, Bakker SJ, Stehouwer CD, Heymans MW, Nijpels G, Hillege HL, Hofman A, Witteman JC, Gansevoort RT, Dekker JM. One risk assessment tool for cardiovascular disease, type 2 diabetes, and chronic kidney disease. Diabetes Care. 2012 Apr; 35(4):741-8.
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  152. Snijder CA, Kortenkamp A, Steegers EA, Jaddoe VW, Hofman A, Hass U, Burdorf A. Intrauterine exposure to mild analgesics during pregnancy and the occurrence of cryptorchidism and hypospadia in the offspring: the Generation R Study. Hum Reprod. 2012 Apr; 27(4):1191-201.
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  154. Sonnenschein-van der Voort AM, Jaddoe VW, Raat H, Moll HA, Hofman A, de Jongste JC, Duijts L. Fetal and infant growth and asthma symptoms in preschool children: the generation R study. Am J Respir Crit Care Med. 2012 Apr 1; 185(7):731-7.
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  155. Wolff NJ, Darlington AS, Hunfeld JA, Jaddoe VW, Hofman A, Raat H, Verhulst FC, Passchier J, Tiemeier H. Concurrent and longitudinal bidirectional relationships between toddlers' chronic pain and mental health: the generation R study. J Pediatr Psychol. 2012 Jun; 37(5):546-56.
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  156. Hafkamp-de Groen E, van Rossem L, de Jongste JC, Mohangoo AD, Moll HA, Jaddoe VW, Hofman A, Mackenbach JP, Raat H. The role of prenatal, perinatal and postnatal factors in the explanation of socioeconomic inequalities in preschool asthma symptoms: the Generation R Study. J Epidemiol Community Health. 2012 Nov; 66(11):1017-24.
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  157. Cents RA, Tiemeier H, Velders FP, Jaddoe VW, Hofman A, Verhulst FC, Lambregtse-van den Berg MP, Hudziak JJ. Maternal smoking during pregnancy and child emotional problems: the relevance of maternal and child 5-HTTLPR genotype. Am J Med Genet B Neuropsychiatr Genet. 2012 Apr; 159B(3):289-97.
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  158. den Heijer T, van der Lijn F, Ikram A, Koudstaal PJ, van der Lugt A, Krestin GP, Vrooman HA, Hofman A, Niessen WJ, Breteler MM. Vascular risk factors, apolipoprotein E, and hippocampal decline on magnetic resonance imaging over a 10-year follow-up. Alzheimers Dement. 2012 Sep; 8(5):417-25.
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  162. Marcus MW, Müskens RP, Ramdas WD, Wolfs RC, De Jong PT, Vingerling JR, Hofman A, Stricker BH, Jansonius NM. Cholesterol-lowering drugs and incident open-angle glaucoma: a population-based cohort study. PLoS One. 2012; 7(1):e29724.
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  163. Snijder CA, Roeleveld N, Te Velde E, Steegers EA, Raat H, Hofman A, Jaddoe VW, Burdorf A. Occupational exposure to chemicals and fetal growth: the Generation R Study. Hum Reprod. 2012 Mar; 27(3):910-20.
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  164. van den Hooven EH, Pierik FH, de Kluizenaar Y, Willemsen SP, Hofman A, van Ratingen SW, Zandveld PY, Mackenbach JP, Steegers EA, Miedema HM, Jaddoe VW. Air pollution exposure during pregnancy, ultrasound measures of fetal growth, and adverse birth outcomes: a prospective cohort study. Environ Health Perspect. 2012 Jan; 120(1):150-6.
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  165. Tharner A, Luijk MP, van Ijzendoorn MH, Bakermans-Kranenburg MJ, Jaddoe VW, Hofman A, Verhulst FC, Tiemeier H. Maternal lifetime history of depression and depressive symptoms in the prenatal and early postnatal period do not predict infant-mother attachment quality in a large, population-based Dutch cohort study. Attach Hum Dev. 2012 Jan; 14(1):63-81.
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  166. Taal HR, Verwoert GC, Demirkan A, Janssens AC, Rice K, Ehret G, Smith AV, Verhaaren BF, Witteman JC, Hofman A, Vernooij MW, Uitterlinden AG, Rivadeneira F, Ikram MA, Levy D, van der Heijden AJ, Jaddoe VW, van Duijn CM. Genome-wide profiling of blood pressure in adults and children. Hypertension. 2012 Feb; 59(2):241-7.
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  167. Paternoster L, Standl M, Chen CM, Ramasamy A, Bønnelykke K, Duijts L, Ferreira MA, Alves AC, Thyssen JP, Albrecht E, Baurecht H, Feenstra B, Sleiman PM, Hysi P, Warrington NM, Curjuric I, Myhre R, Curtin JA, Groen-Blokhuis MM, Kerkhof M, Sääf A, Franke A, Ellinghaus D, Fölster-Holst R, Dermitzakis E, Montgomery SB, Prokisch H, Heim K, Hartikainen AL, Pouta A, Pekkanen J, Blakemore AI, Buxton JL, Kaakinen M, Duffy DL, Madden PA, Heath AC, Montgomery GW, Thompson PJ, Matheson MC, Le Souëf P, St Pourcain B, Smith GD, Henderson J, Kemp JP, Timpson NJ, Deloukas P, Ring SM, Wichmann HE, Müller-Nurasyid M, Novak N, Klopp N, Rodríguez E, McArdle W, Linneberg A, Menné T, Nohr EA, Hofman A, Uitterlinden AG, van Duijn CM, Rivadeneira F, de Jongste JC, van der Valk RJ, Wjst M, Jogi R, Geller F, Boyd HA, Murray JC, Kim C, Mentch F, March M, Mangino M, Spector TD, Bataille V, Pennell CE, Holt PG, Sly P, Tiesler CM, Thiering E, Illig T, Imboden M, Nystad W, Simpson A, Hottenga JJ, Postma D, Koppelman GH, Smit HA, Söderhäll C, Chawes B, Kreiner-Møller E, Bisgaard H, Melén E, Boomsma DI, Custovic A, Jacobsson B, Probst-Hensch NM, Palmer LJ, Glass D, Hakonarson H, Melbye M, Jarvis DL, Jaddoe VW, Gieger C, Strachan DP, Martin NG, Jarvelin MR, Heinrich J, Evans DM, Weidinger S. Meta-analysis of genome-wide association studies identifies three new risk loci for atopic dermatitis. Nat Genet. 2012 Feb; 44(2):187-92.
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  168. Murabito JM, White CC, Kavousi M, Sun YV, Feitosa MF, Nambi V, Lamina C, Schillert A, Coassin S, Bis JC, Broer L, Crawford DC, Franceschini N, Frikke-Schmidt R, Haun M, Holewijn S, Huffman JE, Hwang SJ, Kiechl S, Kollerits B, Montasser ME, Nolte IM, Rudock ME, Senft A, Teumer A, van der Harst P, Vitart V, Waite LL, Wood AR, Wassel CL, Absher DM, Allison MA, Amin N, Arnold A, Asselbergs FW, Aulchenko Y, Bandinelli S, Barbalic M, Boban M, Brown-Gentry K, Couper DJ, Criqui MH, Dehghan A, den Heijer M, Dieplinger B, Ding J, Dörr M, Espinola-Klein C, Felix SB, Ferrucci L, Folsom AR, Fraedrich G, Gibson Q, Goodloe R, Gunjaca G, Haltmayer M, Heiss G, Hofman A, Kieback A, Kiemeney LA, Kolcic I, Kullo IJ, Kritchevsky SB, Lackner KJ, Li X, Lieb W, Lohman K, Meisinger C, Melzer D, Mohler ER, Mudnic I, Mueller T, Navis G, Oberhollenzer F, Olin JW, O'Connell J, O'Donnell CJ, Palmas W, Penninx BW, Petersmann A, Polasek O, Psaty BM, Rantner B, Rice K, Rivadeneira F, Rotter JI, Seldenrijk A, Stadler M, Summerer M, Tanaka T, Tybjaerg-Hansen A, Uitterlinden AG, van Gilst WH, Vermeulen SH, Wild SH, Wild PS, Willeit J, Zeller T, Zemunik T, Zgaga L, Assimes TL, Blankenberg S, Boerwinkle E, Campbell H, Cooke JP, de Graaf J, Herrington D, Kardia SL, Mitchell BD, Murray A, Münzel T, Newman AB, Oostra BA, Rudan I, Shuldiner AR, Snieder H, van Duijn CM, Völker U, Wright AF, Wichmann HE, Wilson JF, Witteman JC, Liu Y, Hayward C, Borecki IB, Ziegler A, North KE, Cupples LA, Kronenberg F. Association between chromosome 9p21 variants and the ankle-brachial index identified by a meta-analysis of 21 genome-wide association studies. Circ Cardiovasc Genet. 2012 Feb 1; 5(1):100-12.
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  169. Uh HW, Deelen J, Beekman M, Helmer Q, Rivadeneira F, Hottenga JJ, Boomsma DI, Hofman A, Uitterlinden AG, Slagboom PE, Böhringer S, Houwing-Duistermaat JJ. How to deal with the early GWAS data when imputing and combining different arrays is necessary. Eur J Hum Genet. 2012 May; 20(5):572-6.
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  170. Ghassabian A, Bongers-Schokking JJ, de Rijke YB, van Mil N, Jaddoe VW, de Muinck Keizer-Schrama SM, Hooijkaas H, Hofman A, Visser W, Roman GC, Visser TJ, Verhulst FC, Tiemeier H. Maternal thyroid autoimmunity during pregnancy and the risk of attention deficit/hyperactivity problems in children: the Generation R Study. Thyroid. 2012 Feb; 22(2):178-86.
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  171. Tuinenburg A, Rutten A, Kavousi M, Leebeek FW, Ypma PF, Laros-van Gorkom BA, Nijziel MR, Kamphuisen PW, Mauser-Bunschoten EP, Roosendaal G, Biesma DH, van der Lugt A, Hofman A, Witteman JC, Bots ML, Schutgens RE. Coronary artery calcification in hemophilia A: no evidence for a protective effect of factor VIII deficiency on atherosclerosis. Arterioscler Thromb Vasc Biol. 2012 Mar; 32(3):799-804.
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  172. Ittermann T, Noord Cv, Friedrich N, Dörr M, Felix SB, Nauck M, Völzke H, Hofman A, Witteman JC, Stricker BH, Wallaschofski H. The association between insulin-like growth factor-I and cardiac repolarization. Growth Horm IGF Res. 2012 Feb; 22(1):1-5.
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  173. Medici M, de Rijke YB, Peeters RP, Visser W, de Muinck Keizer-Schrama SM, Jaddoe VV, Hofman A, Hooijkaas H, Steegers EA, Tiemeier H, Bongers-Schokking JJ, Visser TJ. Maternal early pregnancy and newborn thyroid hormone parameters: the Generation R study. J Clin Endocrinol Metab. 2012 Feb; 97(2):646-52.
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  174. O'Donnell CJ, Kavousi M, Smith AV, Kardia SL, Feitosa MF, Hwang SJ, Sun YV, Province MA, Aspelund T, Dehghan A, Hoffmann U, Bielak LF, Zhang Q, Eiriksdottir G, van Duijn CM, Fox CS, de Andrade M, Kraja AT, Sigurdsson S, Elias-Smale SE, Murabito JM, Launer LJ, van der Lugt A, Kathiresan S, Krestin GP, Herrington DM, Howard TD, Liu Y, Post W, Mitchell BD, O'Connell JR, Shen H, Shuldiner AR, Altshuler D, Elosua R, Salomaa V, Schwartz SM, Siscovick DS, Voight BF, Bis JC, Glazer NL, Psaty BM, Boerwinkle E, Heiss G, Blankenberg S, Zeller T, Wild PS, Schnabel RB, Schillert A, Ziegler A, Münzel TF, White CC, Rotter JI, Nalls M, Oudkerk M, Johnson AD, Newman AB, Uitterlinden AG, Massaro JM, Cunningham J, Harris TB, Hofman A, Peyser PA, Borecki IB, Cupples LA, Gudnason V, Witteman JC. Genome-wide association study for coronary artery calcification with follow-up in myocardial infarction. Circulation. 2011 Dec 20; 124(25):2855-64.
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  175. Sanchez-Juan P, Bishop MT, Aulchenko YS, Brandel JP, Rivadeneira F, Struchalin M, Lambert JC, Amouyel P, Combarros O, Sainz J, Carracedo A, Uitterlinden AG, Hofman A, Zerr I, Kretzschmar HA, Laplanche JL, Knight RS, Will RG, van Duijn CM. Genome-wide study links MTMR7 gene to variant Creutzfeldt-Jakob risk. Neurobiol Aging. 2012 Jul; 33(7):1487.e21-8.
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  176. de Jonge LL, Steegers EA, Ernst GD, Lindemans J, Russcher H, Hofman A, Jaddoe VW. C-reactive protein levels, blood pressure and the risks of gestational hypertensive complications: the Generation R Study. J Hypertens. 2011 Dec; 29(12):2413-21.
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  177. Elens L, Becker ML, Haufroid V, Hofman A, Visser LE, Uitterlinden AG, Stricker BCh, van Schaik RH. Novel CYP3A4 intron 6 single nucleotide polymorphism is associated with simvastatin-mediated cholesterol reduction in the Rotterdam Study. Pharmacogenet Genomics. 2011 Dec; 21(12):861-6.
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  178. Liu F, Struchalin MV, Duijn Kv, Hofman A, Uitterlinden AG, Duijn Cv, Aulchenko YS, Kayser M. Detecting low frequent loss-of-function alleles in genome wide association studies with red hair color as example. PLoS One. 2011; 6(11):e28145.
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  179. Broer L, Koudstaal PJ, Amin N, Rivadeneira F, Uitterlinden AG, Hofman A, Oostra BA, Breteler MM, Ikram MA, van Duijn CM. Association of heat shock proteins with Parkinson's disease. Eur J Epidemiol. 2011 Dec; 26(12):933-5.
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  180. Schrijvers EM, Schürmann B, Koudstaal PJ, van den Bussche H, Van Duijn CM, Hentschel F, Heun R, Hofman A, Jessen F, Kölsch H, Kornhuber J, Peters O, Rivadeneira F, Rüther E, Uitterlinden AG, Riedel-Heller S, Dichgans M, Wiltfang J, Maier W, Breteler MM, Ikram MA. Genome-wide association study of vascular dementia. Stroke. 2012 Feb; 43(2):315-9.
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  181. Gaillard R, de Ridder MA, Verburg BO, Witteman JC, Mackenbach JP, Moll HA, Hofman A, Steegers EA, Jaddoe VW. Individually customised fetal weight charts derived from ultrasound measurements: the Generation R Study. Eur J Epidemiol. 2011 Dec; 26(12):919-26.
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  182. Mitchell GF, Verwoert GC, Tarasov KV, Isaacs A, Smith AV, Rietzschel ER, Tanaka T, Liu Y, Parsa A, Najjar SS, O'Shaughnessy KM, Sigurdsson S, De Buyzere ML, Larson MG, Sie MP, Andrews JS, Post WS, Mattace-Raso FU, McEniery CM, Eiriksdottir G, Segers P, Vasan RS, van Rijn MJ, Howard TD, McArdle PF, Dehghan A, Jewell ES, Newhouse SJ, Bekaert S, Hamburg NM, Newman AB, Hofman A, Scuteri A, De Bacquer D, Arfan Ikram M, Psaty BM, Fuchsberger C, Olden M, Wain LV, Elliott P, Smith NL, Felix JF, Erdmann J, Vita JA, Sutton-Tyrrell K, Sijbrands EJ, Sanna S, Launer LJ, De Meyer T, Johnson AD, Schut AF, Herrington DM, Rivadeneira F, Uda M, Wilkinson IB, Aspelund T, Gillebert TC, Van Bortel L, Benjamin EJ, Oostra BA, Ding J, Gibson Q, Uitterlinden AG, Abecasis GR, Cockcroft JR, Gudnason V, De Backer GG, Ferrucci L, Harris TB, Shuldiner AR, van Duijn CM, Levy D, Lakatta EG, Witteman JC. Common genetic variation in the 3'-BCL11B gene desert is associated with carotid-femoral pulse wave velocity and excess cardiovascular disease risk: the AortaGen Consortium. Circ Cardiovasc Genet. 2012 Feb 1; 5(1):81-90.
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  183. Kilpeläinen TO, Qi L, Brage S, Sharp SJ, Sonestedt E, Demerath E, Ahmad T, Mora S, Kaakinen M, Sandholt CH, Holzapfel C, Autenrieth CS, Hyppönen E, Cauchi S, He M, Kutalik Z, Kumari M, Stancáková A, Meidtner K, Balkau B, Tan JT, Mangino M, Timpson NJ, Song Y, Zillikens MC, Jablonski KA, Garcia ME, Johansson S, Bragg-Gresham JL, Wu Y, van Vliet-Ostaptchouk JV, Onland-Moret NC, Zimmermann E, Rivera NV, Tanaka T, Stringham HM, Silbernagel G, Kanoni S, Feitosa MF, Snitker S, Ruiz JR, Metter J, Larrad MT, Atalay M, Hakanen M, Amin N, Cavalcanti-Proença C, Grøntved A, Hallmans G, Jansson JO, Kuusisto J, Kähönen M, Lutsey PL, Nolan JJ, Palla L, Pedersen O, Pérusse L, Renström F, Scott RA, Shungin D, Sovio U, Tammelin TH, Rönnemaa T, Lakka TA, Uusitupa M, Rios MS, Ferrucci L, Bouchard C, Meirhaeghe A, Fu M, Walker M, Borecki IB, Dedoussis GV, Fritsche A, Ohlsson C, Boehnke M, Bandinelli S, van Duijn CM, Ebrahim S, Lawlor DA, Gudnason V, Harris TB, Sørensen TI, Mohlke KL, Hofman A, Uitterlinden AG, Tuomilehto J, Lehtimäki T, Raitakari O, Isomaa B, Njølstad PR, Florez JC, Liu S, Ness A, Spector TD, Tai ES, Froguel P, Boeing H, Laakso M, Marmot M, Bergmann S, Power C, Khaw KT, Chasman D, Ridker P, Hansen T, Monda KL, Illig T, Järvelin MR, Wareham NJ, Hu FB, Groop LC, Orho-Melander M, Ekelund U, Franks PW, Loos RJ. Physical activity attenuates the influence of FTO variants on obesity risk: a meta-analysis of 218,166 adults and 19,268 children. PLoS Med. 2011 Nov; 8(11):e1001116.
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  184. Teichert M, Visser LE, Uitterlinden AG, Hofman A, Buhre PJ, Straus S, De Smet PA, Stricker BH. Selective serotonin re-uptake inhibiting antidepressants and the risk of overanticoagulation during acenocoumarol maintenance treatment. Br J Clin Pharmacol. 2011 Nov; 72(5):798-805.
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  185. van Rossem L, Vogel I, Moll HA, Jaddoe VW, Hofman A, Mackenbach JP, Raat H. An observational study on socio-economic and ethnic differences in indicators of sedentary behavior and physical activity in preschool children. Prev Med. 2012 Jan; 54(1):55-60.
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  186. Muller O, Mangiacapra F, Ntalianis A, Verhamme KM, Trana C, Hamilos M, Bartunek J, Vanderheyden M, Wyffels E, Heyndrickx GR, van Rooij FJ, Witteman JC, Hofman A, Wijns W, Barbato E, De Bruyne B. Long-term follow-up after fractional flow reserve-guided treatment strategy in patients with an isolated proximal left anterior descending coronary artery stenosis. JACC Cardiovasc Interv. 2011 Nov; 4(11):1175-82.
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  187. Bakker R, Timmermans S, Steegers EA, Hofman A, Jaddoe VW. Folic acid supplements modify the adverse effects of maternal smoking on fetal growth and neonatal complications. J Nutr. 2011 Dec; 141(12):2172-9.
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  188. Surakka I, Isaacs A, Karssen LC, Laurila PP, Middelberg RP, Tikkanen E, Ried JS, Lamina C, Mangino M, Igl W, Hottenga JJ, Lagou V, van der Harst P, Mateo Leach I, Esko T, Kutalik Z, Wainwright NW, Struchalin MV, Sarin AP, Kangas AJ, Viikari JS, Perola M, Rantanen T, Petersen AK, Soininen P, Johansson A, Soranzo N, Heath AC, Papamarkou T, Prokopenko I, Tönjes A, Kronenberg F, Döring A, Rivadeneira F, Montgomery GW, Whitfield JB, Kähönen M, Lehtimäki T, Freimer NB, Willemsen G, de Geus EJ, Palotie A, Sandhu MS, Waterworth DM, Metspalu A, Stumvoll M, Uitterlinden AG, Jula A, Navis G, Wijmenga C, Wolffenbuttel BH, Taskinen MR, Ala-Korpela M, Kaprio J, Kyvik KO, Boomsma DI, Pedersen NL, Gyllensten U, Wilson JF, Rudan I, Campbell H, Pramstaller PP, Spector TD, Witteman JC, Eriksson JG, Salomaa V, Oostra BA, Raitakari OT, Wichmann HE, Gieger C, Järvelin MR, Martin NG, Hofman A, McCarthy MI, Peltonen L, van Duijn CM, Aulchenko YS, Ripatti S. A genome-wide screen for interactions reveals a new locus on 4p15 modifying the effect of waist-to-hip ratio on total cholesterol. PLoS Genet. 2011 Oct; 7(10):e1002333.
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  189. Ikram MA, van der Lugt A, Niessen WJ, Krestin GP, Koudstaal PJ, Hofman A, Breteler MM, Vernooij MW. The Rotterdam Scan Study: design and update up to 2012. Eur J Epidemiol. 2011 Oct; 26(10):811-24.
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  190. Chambers JC, Zhang W, Sehmi J, Li X, Wass MN, Van der Harst P, Holm H, Sanna S, Kavousi M, Baumeister SE, Coin LJ, Deng G, Gieger C, Heard-Costa NL, Hottenga JJ, Kühnel B, Kumar V, Lagou V, Liang L, Luan J, Vidal PM, Mateo Leach I, O'Reilly PF, Peden JF, Rahmioglu N, Soininen P, Speliotes EK, Yuan X, Thorleifsson G, Alizadeh BZ, Atwood LD, Borecki IB, Brown MJ, Charoen P, Cucca F, Das D, de Geus EJ, Dixon AL, Döring A, Ehret G, Eyjolfsson GI, Farrall M, Forouhi NG, Friedrich N, Goessling W, Gudbjartsson DF, Harris TB, Hartikainen AL, Heath S, Hirschfield GM, Hofman A, Homuth G, Hyppönen E, Janssen HL, Johnson T, Kangas AJ, Kema IP, Kühn JP, Lai S, Lathrop M, Lerch MM, Li Y, Liang TJ, Lin JP, Loos RJ, Martin NG, Moffatt MF, Montgomery GW, Munroe PB, Musunuru K, Nakamura Y, O'Donnell CJ, Olafsson I, Penninx BW, Pouta A, Prins BP, Prokopenko I, Puls R, Ruokonen A, Savolainen MJ, Schlessinger D, Schouten JN, Seedorf U, Sen-Chowdhry S, Siminovitch KA, Smit JH, Spector TD, Tan W, Teslovich TM, Tukiainen T, Uitterlinden AG, Van der Klauw MM, Vasan RS, Wallace C, Wallaschofski H, Wichmann HE, Willemsen G, Würtz P, Xu C, Yerges-Armstrong LM, Abecasis GR, Ahmadi KR, Boomsma DI, Caulfield M, Cookson WO, van Duijn CM, Froguel P, Matsuda K, McCarthy MI, Meisinger C, Mooser V, Pietiläinen KH, Schumann G, Snieder H, Sternberg MJ, Stolk RP, Thomas HC, Thorsteinsdottir U, Uda M, Waeber G, Wareham NJ, Waterworth DM, Watkins H, Whitfield JB, Witteman JC, Wolffenbuttel BH, Fox CS, Ala-Korpela M, Stefansson K, Vollenweider P, Völzke H, Schadt EE, Scott J, Järvelin MR, Elliott P, Kooner JS. Genome-wide association study identifies loci influencing concentrations of liver enzymes in plasma. Nat Genet. 2011 Nov; 43(11):1131-8.
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  191. Grallert H, Dupuis J, Bis JC, Dehghan A, Barbalic M, Baumert J, Lu C, Smith NL, Uitterlinden AG, Roberts R, Khuseyinova N, Schnabel RB, Rice KM, Rivadeneira F, Hoogeveen RC, Fontes JD, Meisinger C, Keaney JF, Lemaitre R, Aulchenko YS, Vasan RS, Ellis S, Hazen SL, van Duijn CM, Nelson JJ, März W, Schunkert H, McPherson RM, Stirnadel-Farrant HA, Psaty BM, Gieger C, Siscovick D, Hofman A, Illig T, Cushman M, Yamamoto JF, Rotter JI, Larson MG, Stewart AF, Boerwinkle E, Witteman JC, Tracy RP, Koenig W, Benjamin EJ, Ballantyne CM. Eight genetic loci associated with variation in lipoprotein-associated phospholipase A2 mass and activity and coronary heart disease: meta-analysis of genome-wide association studies from five community-based studies. Eur Heart J. 2012 Jan; 33(2):238-51.
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  192. Bakker R, Kruithof C, Steegers EA, Tiemeier H, Mackenbach JP, Hofman A, Jaddoe VW. Assessment of maternal smoking status during pregnancy and the associations with neonatal outcomes. Nicotine Tob Res. 2011 Dec; 13(12):1250-6.
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  193. van Kempen BJ, Spronk S, Koller MT, Elias-Smale SE, Fleischmann KE, Ikram MA, Krestin GP, Hofman A, Witteman JC, Hunink MG. Comparative effectiveness and cost-effectiveness of computed tomography screening for coronary artery calcium in asymptomatic individuals. J Am Coll Cardiol. 2011 Oct 11; 58(16):1690-701.
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  194. van Durme YM, Lahousse L, Verhamme KM, Stolk L, Eijgelsheim M, Loth DW, Uitterlinden AG, Breteler MM, Joos GF, Hofman A, Stricker BH, Brusselle GG. Mendelian randomization study of interleukin-6 in chronic obstructive pulmonary disease. Respiration. 2011; 82(6):530-8.
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  195. Ohlsson C, Wallaschofski H, Lunetta KL, Stolk L, Perry JR, Koster A, Petersen AK, Eriksson J, Lehtimäki T, Huhtaniemi IT, Hammond GL, Maggio M, Coviello AD, Ferrucci L, Heier M, Hofman A, Holliday KL, Jansson JO, Kähönen M, Karasik D, Karlsson MK, Kiel DP, Liu Y, Ljunggren O, Lorentzon M, Lyytikäinen LP, Meitinger T, Mellström D, Melzer D, Miljkovic I, Nauck M, Nilsson M, Penninx B, Pye SR, Vasan RS, Reincke M, Rivadeneira F, Tajar A, Teumer A, Uitterlinden AG, Ulloor J, Viikari J, Völker U, Völzke H, Wichmann HE, Wu TS, Zhuang WV, Ziv E, Wu FC, Raitakari O, Eriksson A, Bidlingmaier M, Harris TB, Murray A, de Jong FH, Murabito JM, Bhasin S, Vandenput L, Haring R. Genetic determinants of serum testosterone concentrations in men. PLoS Genet. 2011 Oct; 7(10):e1002313.
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  196. Raat H, Wijtzes A, Jaddoe VW, Moll HA, Hofman A, Mackenbach JP. The health impact of social disadvantage in early childhood; the Generation R study. Early Hum Dev. 2011 Nov; 87(11):729-33.
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  197. Visser AM, Jaddoe VW, Breteler MM, Hofman A, Moll HA, Arts WF. Frequent fever episodes and the risk of febrile seizures: the Generation R study. Eur J Paediatr Neurol. 2012 Jan; 16(1):29-34.
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  198. Ramdas WD, Wolfs RC, Hofman A, de Jong PT, Vingerling JR, Jansonius NM. Heidelberg Retina Tomograph (HRT3) in population-based epidemiology: normative values and criteria for glaucomatous optic neuropathy. Ophthalmic Epidemiol. 2011 Oct; 18(5):198-210.
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  199. Ramdas WD, Rizopoulos D, Wolfs RC, Hofman A, de Jong PT, Vingerling JR, Jansonius NM. Defining glaucomatous optic neuropathy from a continuous measure of optic nerve damage - the optimal cut-off point for risk-factor analysis in population-based epidemiology. Ophthalmic Epidemiol. 2011 Oct; 18(5):211-6.
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  200. Dierckx B, Tharner A, Tulen JH, Jaddoe VW, Hofman A, Verhulst FC, Tiemeier H. Spot the red herring: breastfeeding, fruitpurée, and infant autonomic functioning-the generation R study. Pediatr Res. 2011 Oct; 70(4):417-22.
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  201. Kiefte-de Jong JC, Saridjan NS, Escher JC, Jaddoe VW, Hofman A, Tiemeier H, Moll HA. Cortisol diurnal rhythm and stress reactivity in constipation and abdominal pain: the Generation R Study. J Pediatr Gastroenterol Nutr. 2011 Oct; 53(4):394-400.
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  202. Duijts L, Jaddoe VW, van der Valk RJ, Henderson JA, Hofman A, Raat H, Steegers EA, Moll HA, de Jongste JC. Fetal exposure to maternal and paternal smoking and the risks of wheezing in preschool children: the generation R study. Chest. 2012 Apr; 141(4):876-85.
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  203. Böger CA, Gorski M, Li M, Hoffmann MM, Huang C, Yang Q, Teumer A, Krane V, O'Seaghdha CM, Kutalik Z, Wichmann HE, Haak T, Boes E, Coassin S, Coresh J, Kollerits B, Haun M, Paulweber B, Köttgen A, Li G, Shlipak MG, Powe N, Hwang SJ, Dehghan A, Rivadeneira F, Uitterlinden A, Hofman A, Beckmann JS, Krämer BK, Witteman J, Bochud M, Siscovick D, Rettig R, Kronenberg F, Wanner C, Thadhani RI, Heid IM, Fox CS, Kao WH. Association of eGFR-Related Loci Identified by GWAS with Incident CKD and ESRD. PLoS Genet. 2011 Sep; 7(9):e1002292.
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  204. Ijsselstijn L, Dekker LJ, Stingl C, van der Weiden MM, Hofman A, Kros JM, Koudstaal PJ, Sillevis Smitt PA, Ikram MA, Breteler MM, Luider TM. Serum levels of pregnancy zone protein are elevated in presymptomatic Alzheimer's disease. J Proteome Res. 2011 Nov 4; 10(11):4902-10.
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  205. Soler Artigas M, Loth DW, Wain LV, Gharib SA, Obeidat M, Tang W, Zhai G, Zhao JH, Smith AV, Huffman JE, Albrecht E, Jackson CM, Evans DM, Cadby G, Fornage M, Manichaikul A, Lopez LM, Johnson T, Aldrich MC, Aspelund T, Barroso I, Campbell H, Cassano PA, Couper DJ, Eiriksdottir G, Franceschini N, Garcia M, Gieger C, Gislason GK, Grkovic I, Hammond CJ, Hancock DB, Harris TB, Ramasamy A, Heckbert SR, Heliövaara M, Homuth G, Hysi PG, James AL, Jankovic S, Joubert BR, Karrasch S, Klopp N, Koch B, Kritchevsky SB, Launer LJ, Liu Y, Loehr LR, Lohman K, Loos RJ, Lumley T, Al Balushi KA, Ang WQ, Barr RG, Beilby J, Blakey JD, Boban M, Boraska V, Brisman J, Britton JR, Brusselle GG, Cooper C, Curjuric I, Dahgam S, Deary IJ, Ebrahim S, Eijgelsheim M, Francks C, Gaysina D, Granell R, Gu X, Hankinson JL, Hardy R, Harris SE, Henderson J, Henry A, Hingorani AD, Hofman A, Holt PG, Hui J, Hunter ML, Imboden M, Jameson KA, Kerr SM, Kolcic I, Kronenberg F, Liu JZ, Marchini J, McKeever T, Morris AD, Olin AC, Porteous DJ, Postma DS, Rich SS, Ring SM, Rivadeneira F, Rochat T, Sayer AA, Sayers I, Sly PD, Smith GD, Sood A, Starr JM, Uitterlinden AG, Vonk JM, Wannamethee SG, Whincup PH, Wijmenga C, Williams OD, Wong A, Mangino M, Marciante KD, McArdle WL, Meibohm B, Morrison AC, North KE, Omenaas E, Palmer LJ, Pietiläinen KH, Pin I, Pola Sbreve Ek O, Pouta A, Psaty BM, Hartikainen AL, Rantanen T, Ripatti S, Rotter JI, Rudan I, Rudnicka AR, Schulz H, Shin SY, Spector TD, Surakka I, Vitart V, Völzke H, Wareham NJ, Warrington NM, Wichmann HE, Wild SH, Wilk JB, Wjst M, Wright AF, Zgaga L, Zemunik T, Pennell CE, Nyberg F, Kuh D, Holloway JW, Boezen HM, Lawlor DA, Morris RW, Probst-Hensch N, Kaprio J, Wilson JF, Hayward C, Kähönen M, Heinrich J, Musk AW, Jarvis DL, Gläser S, Järvelin MR, Ch Stricker BH, Elliott P, O'Connor GT, Strachan DP, London SJ, Hall IP, Gudnason V, Tobin MD. Genome-wide association and large-scale follow up identifies 16 new loci influencing lung function. Nat Genet. 2011 Nov; 43(11):1082-90.
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  206. Newson RS, Felix JF, Heeringa J, Hofman A, Witteman JC, Tiemeier H. Association between serum cholesterol and noncardiovascular mortality in older age. J Am Geriatr Soc. 2011 Oct; 59(10):1779-85.
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  207. Wieberdink RG, Poels MM, Vernooij MW, Koudstaal PJ, Hofman A, van der Lugt A, Breteler MM, Ikram MA. Serum lipid levels and the risk of intracerebral hemorrhage: the Rotterdam Study. Arterioscler Thromb Vasc Biol. 2011 Dec; 31(12):2982-9.
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  208. van de Ven AC, Netea-Maier RT, Medici M, Sweep FC, Ross HA, Hofman A, de Graaf J, Kiemeney LA, Hermus AR, Peeters RP, Visser TJ, den Heijer M. Underestimation of effect of thyroid function parameters on morbidity and mortality due to intra-individual variation. J Clin Endocrinol Metab. 2011 Dec; 96(12):E2014-7.
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  209. Bis JC, Kavousi M, Franceschini N, Isaacs A, Abecasis GR, Schminke U, Post WS, Smith AV, Cupples LA, Markus HS, Schmidt R, Huffman JE, Lehtimäki T, Baumert J, Münzel T, Heckbert SR, Dehghan A, North K, Oostra B, Bevan S, Stoegerer EM, Hayward C, Raitakari O, Meisinger C, Schillert A, Sanna S, Völzke H, Cheng YC, Thorsson B, Fox CS, Rice K, Rivadeneira F, Nambi V, Halperin E, Petrovic KE, Peltonen L, Wichmann HE, Schnabel RB, Dörr M, Parsa A, Aspelund T, Demissie S, Kathiresan S, Reilly MP, Taylor K, Uitterlinden A, Couper DJ, Sitzer M, Kähönen M, Illig T, Wild PS, Orru M, Lüdemann J, Shuldiner AR, Eiriksdottir G, White CC, Rotter JI, Hofman A, Seissler J, Zeller T, Usala G, Ernst F, Launer LJ, D'Agostino RB, O'Leary DH, Ballantyne C, Thiery J, Ziegler A, Lakatta EG, Chilukoti RK, Harris TB, Wolf PA, Psaty BM, Polak JF, Li X, Rathmann W, Uda M, Boerwinkle E, Klopp N, Schmidt H, Wilson JF, Viikari J, Koenig W, Blankenberg S, Newman AB, Witteman J, Heiss G, Duijn Cv, Scuteri A, Homuth G, Mitchell BD, Gudnason V, O'Donnell CJ. Meta-analysis of genome-wide association studies from the CHARGE consortium identifies common variants associated with carotid intima media thickness and plaque. Nat Genet. 2011 Oct; 43(10):940-7.
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  213. Hofman A, van Duijn CM, Franco OH, Ikram MA, Janssen HL, Klaver CC, Kuipers EJ, Nijsten TE, Stricker BH, Tiemeier H, Uitterlinden AG, Vernooij MW, Witteman JC. The Rotterdam Study: 2012 objectives and design update. Eur J Epidemiol. 2011 Aug; 26(8):657-86.
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  214. Ramdas WD, Wolfs RC, Hofman A, de Jong PT, Vingerling JR, Jansonius NM. Ocular perfusion pressure and the incidence of glaucoma: real effect or artifact? The Rotterdam Study. Invest Ophthalmol Vis Sci. 2011 Aug; 52(9):6875-81.
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  215. Ramdas WD, van Koolwijk LM, Cree AJ, Janssens AC, Amin N, de Jong PT, Wolfs RC, Gibson J, Kirwan JF, Hofman A, Rivadeneira F, Oostra BA, Uitterlinden AG, Ennis S, Lotery AJ, Lemij HG, Klaver CC, Vingerling JR, Jansonius NM, van Duijn CM. Clinical implications of old and new genes for open-angle glaucoma. Ophthalmology. 2011 Dec; 118(12):2389-97.
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  216. Bos D, Ikram MA, Elias-Smale SE, Krestin GP, Hofman A, Witteman JC, van der Lugt A, Vernooij MW. Calcification in major vessel beds relates to vascular brain disease. Arterioscler Thromb Vasc Biol. 2011 Oct; 31(10):2331-7.
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  217. Verhaaren BF, de Boer R, Vernooij MW, Rivadeneira F, Uitterlinden AG, Hofman A, Krestin GP, van der Lugt A, Niessen WJ, Breteler MM, Ikram MA. Replication study of chr17q25 with cerebral white matter lesion volume. Stroke. 2011 Nov; 42(11):3297-9.
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  218. Day-Williams AG, Southam L, Panoutsopoulou K, Rayner NW, Esko T, Estrada K, Helgadottir HT, Hofman A, Ingvarsson T, Jonsson H, Keis A, Kerkhof HJ, Thorleifsson G, Arden NK, Carr A, Chapman K, Deloukas P, Loughlin J, McCaskie A, Ollier WE, Ralston SH, Spector TD, Wallis GA, Wilkinson JM, Aslam N, Birell F, Carluke I, Joseph J, Rai A, Reed M, Walker K, Doherty SA, Jonsdottir I, Maciewicz RA, Muir KR, Metspalu A, Rivadeneira F, Stefansson K, Styrkarsdottir U, Uitterlinden AG, van Meurs JB, Zhang W, Valdes AM, Doherty M, Zeggini E. A variant in MCF2L is associated with osteoarthritis. Am J Hum Genet. 2011 Sep 9; 89(3):446-50.
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  219. Székely E, Herba CM, Arp PP, Uitterlinden AG, Jaddoe VW, Hofman A, Verhulst FC, Hudziak JJ, Tiemeier H. Recognition of scared faces and the serotonin transporter gene in young children: the Generation R Study. J Child Psychol Psychiatry. 2011 Dec; 52(12):1279-86.
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  220. Bakker R, Steegers EA, Hofman A, Jaddoe VW. Blood pressure in different gestational trimesters, fetal growth, and the risk of adverse birth outcomes: the generation R study. Am J Epidemiol. 2011 Oct 1; 174(7):797-806.
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  221. Kuningas M, Estrada K, Hsu YH, Nandakumar K, Uitterlinden AG, Lunetta KL, van Duijn CM, Karasik D, Hofman A, Murabito J, Rivadeneira F, Kiel DP, Tiemeier H. Large common deletions associate with mortality at old age. Hum Mol Genet. 2011 Nov 1; 20(21):4290-6.
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  222. van den Bouwhuijsen QJ, Vernooij MW, Hofman A, Krestin GP, van der Lugt A, Witteman JC. Determinants of magnetic resonance imaging detected carotid plaque components: the Rotterdam Study. Eur Heart J. 2012 Jan; 33(2):221-9.
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  223. Gaillard R, Bakker R, Willemsen SP, Hofman A, Steegers EA, Jaddoe VW. Blood pressure tracking during pregnancy and the risk of gestational hypertensive disorders: the Generation R Study. Eur Heart J. 2011 Dec; 32(24):3088-97.
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  224. Hoorn EJ, Rivadeneira F, van Meurs JB, Ziere G, Stricker BH, Hofman A, Pols HA, Zietse R, Uitterlinden AG, Zillikens MC. Mild hyponatremia as a risk factor for fractures: the Rotterdam Study. J Bone Miner Res. 2011 Aug; 26(8):1822-8.
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  225. Mohangoo AD, de Koning HJ, de Jongste JC, Landgraf JM, van der Wouden JC, Jaddoe VW, Hofman A, Moll HA, Mackenbach JP, Raat H. Asthma-like symptoms in the first year of life and health-related quality of life at age 12 months: the Generation R study. Qual Life Res. 2012 Apr; 21(3):545-54.
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  226. Kuningas M, McQuillan R, Wilson JF, Hofman A, van Duijn CM, Uitterlinden AG, Tiemeier H. Runs of homozygosity do not influence survival to old age. PLoS One. 2011; 6(7):e22580.
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  227. Walter S, Atzmon G, Demerath EW, Garcia ME, Kaplan RC, Kumari M, Lunetta KL, Milaneschi Y, Tanaka T, Tranah GJ, Völker U, Yu L, Arnold A, Benjamin EJ, Biffar R, Buchman AS, Boerwinkle E, Couper D, De Jager PL, Evans DA, Harris TB, Hoffmann W, Hofman A, Karasik D, Kiel DP, Kocher T, Kuningas M, Launer LJ, Lohman KK, Lutsey PL, Mackenbach J, Marciante K, Psaty BM, Reiman EM, Rotter JI, Seshadri S, Shardell MD, Smith AV, van Duijn C, Walston J, Zillikens MC, Bandinelli S, Baumeister SE, Bennett DA, Ferrucci L, Gudnason V, Kivimaki M, Liu Y, Murabito JM, Newman AB, Tiemeier H, Franceschini N. A genome-wide association study of aging. Neurobiol Aging. 2011 Nov; 32(11):2109.e15-28.
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  228. Mook-Kanamori DO, Durmus B, Sovio U, Hofman A, Raat H, Steegers EA, Jarvelin MR, Jaddoe VW. Fetal and infant growth and the risk of obesity during early childhood: the Generation R Study. Eur J Endocrinol. 2011 Oct; 165(4):623-30.
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  229. Luijk MP, Roisman GI, Haltigan JD, Tiemeier H, Booth-Laforce C, van Ijzendoorn MH, Belsky J, Uitterlinden AG, Jaddoe VW, Hofman A, Verhulst FC, Tharner A, Bakermans-Kranenburg MJ. Dopaminergic, serotonergic, and oxytonergic candidate genes associated with infant attachment security and disorganization? In search of main and interaction effects. J Child Psychol Psychiatry. 2011 Dec; 52(12):1295-307.
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  230. Tas U, Verhagen AP, Bierma-Zeinstra SM, Hofman A, Pols HA, Koes BW. Course and prognostic factors of disability in community-dwelling older people with mild disability: the Rotterdam Study. Australas J Ageing. 2012 Mar; 31(1):28-33.
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  231. van Loon JE, de Maat MP, Hofman A, Witteman JC, Leebeek FW. Relationship between thrombospondin gene variations, von Willebrand factor levels and the risk of coronary heart disease in an older population. J Thromb Haemost. 2011 Jul; 9(7):1415-7.
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  234. Luijk MP, Tharner A, Bakermans-Kranenburg MJ, van Ijzendoorn MH, Jaddoe VW, Hofman A, Verhulst FC, Tiemeier H. The association between parenting and attachment security is moderated by a polymorphism in the mineralocorticoid receptor gene: evidence for differential susceptibility. Biol Psychol. 2011 Sep; 88(1):37-40.
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  235. Kilpeläinen TO, Zillikens MC, Stancákova A, Finucane FM, Ried JS, Langenberg C, Zhang W, Beckmann JS, Luan J, Vandenput L, Styrkarsdottir U, Zhou Y, Smith AV, Zhao JH, Amin N, Vedantam S, Shin SY, Haritunians T, Fu M, Feitosa MF, Kumari M, Halldorsson BV, Tikkanen E, Mangino M, Hayward C, Song C, Arnold AM, Aulchenko YS, Oostra BA, Campbell H, Cupples LA, Davis KE, Döring A, Eiriksdottir G, Estrada K, Fernández-Real JM, Garcia M, Gieger C, Glazer NL, Guiducci C, Hofman A, Humphries SE, Isomaa B, Jacobs LC, Jula A, Karasik D, Karlsson MK, Khaw KT, Kim LJ, Kivimäki M, Klopp N, Kühnel B, Kuusisto J, Liu Y, Ljunggren O, Lorentzon M, Luben RN, McKnight B, Mellström D, Mitchell BD, Mooser V, Moreno JM, Männistö S, O'Connell JR, Pascoe L, Peltonen L, Peral B, Perola M, Psaty BM, Salomaa V, Savage DB, Semple RK, Skaric-Juric T, Sigurdsson G, Song KS, Spector TD, Syvänen AC, Talmud PJ, Thorleifsson G, Thorsteinsdottir U, Uitterlinden AG, van Duijn CM, Vidal-Puig A, Wild SH, Wright AF, Clegg DJ, Schadt E, Wilson JF, Rudan I, Ripatti S, Borecki IB, Shuldiner AR, Ingelsson E, Jansson JO, Kaplan RC, Gudnason V, Harris TB, Groop L, Kiel DP, Rivadeneira F, Walker M, Barroso I, Vollenweider P, Waeber G, Chambers JC, Kooner JS, Soranzo N, Hirschhorn JN, Stefansson K, Wichmann HE, Ohlsson C, O'Rahilly S, Wareham NJ, Speliotes EK, Fox CS, Laakso M, Loos RJ. Genetic variation near IRS1 associates with reduced adiposity and an impaired metabolic profile. Nat Genet. 2011 Aug; 43(8):753-60.
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  236. Verhaegh SJ, de Vogel CP, Riesbeck K, Lafontaine ER, Murphy TF, Verbrugh HA, Jaddoe VW, Hofman A, Moll HA, van Belkum A, Hays JP. Temporal development of the humoral immune response to surface antigens of Moraxella catarrhalis in young infants. Vaccine. 2011 Aug 5; 29(34):5603-10.
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  237. Boehringer S, van der Lijn F, Liu F, Günther M, Sinigerova S, Nowak S, Ludwig KU, Herberz R, Klein S, Hofman A, Uitterlinden AG, Niessen WJ, Breteler MM, van der Lugt A, Würtz RP, Nöthen MM, Horsthemke B, Wieczorek D, Mangold E, Kayser M. Genetic determination of human facial morphology: links between cleft-lips and normal variation. Eur J Hum Genet. 2011 Nov; 19(11):1192-7.
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  238. Heppe DH, van Dam RM, Willemsen SP, den Breeijen H, Raat H, Hofman A, Steegers EA, Jaddoe VW. Maternal milk consumption, fetal growth, and the risks of neonatal complications: the Generation R Study. Am J Clin Nutr. 2011 Aug; 94(2):501-9.
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  239. Elias-Smale SE, Kavousi M, Verwoert GC, Koller MT, Steyerberg EW, Mattace-Raso FU, Hofman A, Hoeks AP, Reneman RS, Witteman JC. Common carotid intima-media thickness in cardiovascular risk stratification of older people: the Rotterdam Study. Eur J Prev Cardiol. 2012 Aug; 19(4):698-705.
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  240. Wieberdink RG, Ho L, Ikram MK, Koudstaal PJ, Hofman A, de Jong PT, Vingerling JR, Breteler MM. Age-related macular degeneration and the risk of stroke: the Rotterdam study. Stroke. 2011 Aug; 42(8):2138-42.
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  241. Gaillard R, Bakker R, Steegers EA, Hofman A, Jaddoe VW. Maternal age during pregnancy is associated with third trimester blood pressure level: the generation R study. Am J Hypertens. 2011 Sep; 24(9):1046-53.
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  242. den Heijer T, Tiemeier H, Luijendijk HJ, van der Lijn F, Koudstaal PJ, Hofman A, Breteler MM. A study of the bidirectional association between hippocampal volume on magnetic resonance imaging and depression in the elderly. Biol Psychiatry. 2011 Jul 15; 70(2):191-7.
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  243. Tromp II, Kiefte-de Jong JC, Lebon A, Renders CM, Jaddoe VW, Hofman A, de Jongste JC, Moll HA. The introduction of allergenic foods and the development of reported wheezing and eczema in childhood: the Generation R study. Arch Pediatr Adolesc Med. 2011 Oct; 165(10):933-8.
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  244. Ho L, van Leeuwen R, Witteman JC, van Duijn CM, Uitterlinden AG, Hofman A, de Jong PT, Vingerling JR, Klaver CC. Reducing the genetic risk of age-related macular degeneration with dietary antioxidants, zinc, and ?-3 fatty acids: the Rotterdam study. Arch Ophthalmol. 2011 Jun; 129(6):758-66.
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  245. Fornage M, Debette S, Bis JC, Schmidt H, Ikram MA, Dufouil C, Sigurdsson S, Lumley T, DeStefano AL, Fazekas F, Vrooman HA, Shibata DK, Maillard P, Zijdenbos A, Smith AV, Gudnason H, de Boer R, Cushman M, Mazoyer B, Heiss G, Vernooij MW, Enzinger C, Glazer NL, Beiser A, Knopman DS, Cavalieri M, Niessen WJ, Harris TB, Petrovic K, Lopez OL, Au R, Lambert JC, Hofman A, Gottesman RF, Garcia M, Heckbert SR, Atwood LD, Catellier DJ, Uitterlinden AG, Yang Q, Smith NL, Aspelund T, Romero JR, Rice K, Taylor KD, Nalls MA, Rotter JI, Sharrett R, van Duijn CM, Amouyel P, Wolf PA, Gudnason V, van der Lugt A, Boerwinkle E, Psaty BM, Seshadri S, Tzourio C, Breteler MM, Mosley TH, Schmidt R, Longstreth WT, DeCarli C, Launer LJ. Genome-wide association studies of cerebral white matter lesion burden: the CHARGE consortium. Ann Neurol. 2011 Jun; 69(6):928-39.
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  246. Taal HR, Geelhoed JJ, Steegers EA, Hofman A, Moll HA, Lequin M, van der Heijden AJ, Jaddoe VW. Maternal smoking during pregnancy and kidney volume in the offspring: the Generation R Study. Pediatr Nephrol. 2011 Aug; 26(8):1275-83.
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  247. Elias-Smale SE, Wieberdink RG, Odink AE, Hofman A, Hunink MG, Koudstaal PJ, Krestin GP, Breteler MM, van der Lugt A, Witteman JC. Burden of atherosclerosis improves the prediction of coronary heart disease but not cerebrovascular events: the Rotterdam Study. Eur Heart J. 2011 Aug; 32(16):2050-8.
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  248. Wild PS, Zeller T, Schillert A, Szymczak S, Sinning CR, Deiseroth A, Schnabel RB, Lubos E, Keller T, Eleftheriadis MS, Bickel C, Rupprecht HJ, Wilde S, Rossmann H, Diemert P, Cupples LA, Perret C, Erdmann J, Stark K, Kleber ME, Epstein SE, Voight BF, Kuulasmaa K, Li M, Schäfer AS, Klopp N, Braund PS, Sager HB, Demissie S, Proust C, König IR, Wichmann HE, Reinhard W, Hoffmann MM, Virtamo J, Burnett MS, Siscovick D, Wiklund PG, Qu L, El Mokthari NE, Thompson JR, Peters A, Smith AV, Yon E, Baumert J, Hengstenberg C, März W, Amouyel P, Devaney J, Schwartz SM, Saarela O, Mehta NN, Rubin D, Silander K, Hall AS, Ferrieres J, Harris TB, Melander O, Kee F, Hakonarson H, Schrezenmeir J, Gudnason V, Elosua R, Arveiler D, Evans A, Rader DJ, Illig T, Schreiber S, Bis JC, Altshuler D, Kavousi M, Witteman JC, Uitterlinden AG, Hofman A, Folsom AR, Barbalic M, Boerwinkle E, Kathiresan S, Reilly MP, O'Donnell CJ, Samani NJ, Schunkert H, Cambien F, Lackner KJ, Tiret L, Salomaa V, Munzel T, Ziegler A, Blankenberg S. A genome-wide association study identifies LIPA as a susceptibility gene for coronary artery disease. Circ Cardiovasc Genet. 2011 Aug 1; 4(4):403-12.
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  249. Durmus B, Kruithof CJ, Gillman MH, Willemsen SP, Hofman A, Raat H, Eilers PH, Steegers EA, Jaddoe VW. Parental smoking during pregnancy, early growth, and risk of obesity in preschool children: the Generation R Study. Am J Clin Nutr. 2011 Jul; 94(1):164-71.
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  250. Timmermans S, Steegers-Theunissen RP, Vujkovic M, Bakker R, den Breeijen H, Raat H, Russcher H, Lindemans J, Hofman A, Jaddoe VW, Steegers EA. Major dietary patterns and blood pressure patterns during pregnancy: the Generation R Study. Am J Obstet Gynecol. 2011 Oct; 205(4):337.e1-12.
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  251. Luijendijk HJ, Stricker BH, Wieberdink RG, Koudstaal PJ, Hofman A, Breteler MM, Tiemeier H. Transient ischemic attack and incident depression. Stroke. 2011 Jul; 42(7):1857-61.
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  252. Tas U, Steyerberg EW, Bierma-Zeinstra SM, Hofman A, Koes BW, Verhagen AP. Age, gender and disability predict future disability in older people: the Rotterdam Study. BMC Geriatr. 2011; 11:22.
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  253. van Woudenbergh GJ, Kuijsten A, Sijbrands EJ, Hofman A, Witteman JC, Feskens EJ. Glycemic index and glycemic load and their association with C-reactive protein and incident type 2 diabetes. J Nutr Metab. 2011; 2011:623076.
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  254. Rours GI, Duijts L, Moll HA, Arends LR, de Groot R, Jaddoe VW, Hofman A, Steegers EA, Mackenbach JP, Ott A, Willemse HF, van der Zwaan EA, Verkooijen RP, Verbrugh HA. Chlamydia trachomatis infection during pregnancy associated with preterm delivery: a population-based prospective cohort study. Eur J Epidemiol. 2011 Jun; 26(6):493-502.
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  255. Ghassabian A, Bongers-Schokking JJ, Henrichs J, Jaddoe VW, Visser TJ, Visser W, de Muinck Keizer-Schrama SM, Hooijkaas H, Steegers EA, Hofman A, Verhulst FC, van der Ende J, de Rijke YB, Tiemeier H. Maternal thyroid function during pregnancy and behavioral problems in the offspring: the generation R study. Pediatr Res. 2011 May; 69(5 Pt 1):454-9.
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  256. Gaillard R, Steegers EA, Hofman A, Jaddoe VW. Associations of maternal obesity with blood pressure and the risks of gestational hypertensive disorders. The Generation R Study. J Hypertens. 2011 May; 29(5):937-44.
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  257. Mesker DJ, Poels MM, Ikram MA, Vernooij MW, Hofman A, Vrooman HA, van der Lugt A, Breteler MM. Lobar distribution of cerebral microbleeds: the Rotterdam Scan Study. Arch Neurol. 2011 May; 68(5):656-9.
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  258. Kohli MA, Lucae S, Saemann PG, Schmidt MV, Demirkan A, Hek K, Czamara D, Alexander M, Salyakina D, Ripke S, Hoehn D, Specht M, Menke A, Hennings J, Heck A, Wolf C, Ising M, Schreiber S, Czisch M, Müller MB, Uhr M, Bettecken T, Becker A, Schramm J, Rietschel M, Maier W, Bradley B, Ressler KJ, Nöthen MM, Cichon S, Craig IW, Breen G, Lewis CM, Hofman A, Tiemeier H, van Duijn CM, Holsboer F, Müller-Myhsok B, Binder EB. The neuronal transporter gene SLC6A15 confers risk to major depression. Neuron. 2011 Apr 28; 70(2):252-65.
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  259. Velders FP, Dieleman G, Henrichs J, Jaddoe VW, Hofman A, Verhulst FC, Hudziak JJ, Tiemeier H. Prenatal and postnatal psychological symptoms of parents and family functioning: the impact on child emotional and behavioural problems. Eur Child Adolesc Psychiatry. 2011 Jul; 20(7):341-50.
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  260. Duncan EL, Danoy P, Kemp JP, Leo PJ, McCloskey E, Nicholson GC, Eastell R, Prince RL, Eisman JA, Jones G, Sambrook PN, Reid IR, Dennison EM, Wark J, Richards JB, Uitterlinden AG, Spector TD, Esapa C, Cox RD, Brown SD, Thakker RV, Addison KA, Bradbury LA, Center JR, Cooper C, Cremin C, Estrada K, Felsenberg D, Glüer CC, Hadler J, Henry MJ, Hofman A, Kotowicz MA, Makovey J, Nguyen SC, Nguyen TV, Pasco JA, Pryce K, Reid DM, Rivadeneira F, Roux C, Stefansson K, Styrkarsdottir U, Thorleifsson G, Tichawangana R, Evans DM, Brown MA. Genome-wide association study using extreme truncate selection identifies novel genes affecting bone mineral density and fracture risk. PLoS Genet. 2011 Apr; 7(4):e1001372.
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  261. Smith NL, Huffman JE, Strachan DP, Huang J, Dehghan A, Trompet S, Lopez LM, Shin SY, Baumert J, Vitart V, Bis JC, Wild SH, Rumley A, Yang Q, Uitterlinden AG, Stott DJ, Davies G, Carter AM, Thorand B, Polašek O, McKnight B, Campbell H, Rudnicka AR, Chen MH, Buckley BM, Harris SE, Peters A, Pulanic D, Lumley T, de Craen AJ, Liewald DC, Gieger C, Campbell S, Ford I, Gow AJ, Luciano M, Porteous DJ, Guo X, Sattar N, Tenesa A, Cushman M, Slagboom PE, Visscher PM, Spector TD, Illig T, Rudan I, Bovill EG, Wright AF, McArdle WL, Tofler G, Hofman A, Westendorp RG, Starr JM, Grant PJ, Karakas M, Hastie ND, Psaty BM, Wilson JF, Lowe GD, O'Donnell CJ, Witteman JC, Jukema JW, Deary IJ, Soranzo N, Koenig W, Hayward C. Genetic predictors of fibrin D-dimer levels in healthy adults. Circulation. 2011 May 3; 123(17):1864-72.
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  262. Zhai G, Teumer A, Stolk L, Perry JR, Vandenput L, Coviello AD, Koster A, Bell JT, Bhasin S, Eriksson J, Eriksson A, Ernst F, Ferrucci L, Frayling TM, Glass D, Grundberg E, Haring R, Hedman AK, Hofman A, Kiel DP, Kroemer HK, Liu Y, Lunetta KL, Maggio M, Lorentzon M, Mangino M, Melzer D, Miljkovic I, Nica A, Penninx BW, Vasan RS, Rivadeneira F, Small KS, Soranzo N, Uitterlinden AG, Völzke H, Wilson SG, Xi L, Zhuang WV, Harris TB, Murabito JM, Ohlsson C, Murray A, de Jong FH, Spector TD, Wallaschofski H. Eight common genetic variants associated with serum DHEAS levels suggest a key role in ageing mechanisms. PLoS Genet. 2011 Apr; 7(4):e1002025.
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  263. Ernst GD, de Jonge LL, Hofman A, Lindemans J, Russcher H, Steegers EA, Jaddoe VW. C-reactive protein levels in early pregnancy, fetal growth patterns, and the risk for neonatal complications: the Generation R Study. Am J Obstet Gynecol. 2011 Aug; 205(2):132.e1-12.
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  264. Schrijvers EM, Koudstaal PJ, Hofman A, Breteler MM. Plasma clusterin and the risk of Alzheimer disease. JAMA. 2011 Apr 6; 305(13):1322-6.
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  265. Schumann G, Coin LJ, Lourdusamy A, Charoen P, Berger KH, Stacey D, Desrivières S, Aliev FA, Khan AA, Amin N, Aulchenko YS, Bakalkin G, Bakker SJ, Balkau B, Beulens JW, Bilbao A, de Boer RA, Beury D, Bots ML, Breetvelt EJ, Cauchi S, Cavalcanti-Proença C, Chambers JC, Clarke TK, Dahmen N, de Geus EJ, Dick D, Ducci F, Easton A, Edenberg HJ, Esko T, Esk T, Fernández-Medarde A, Foroud T, Freimer NB, Girault JA, Grobbee DE, Guarrera S, Gudbjartsson DF, Hartikainen AL, Heath AC, Hesselbrock V, Hofman A, Hottenga JJ, Isohanni MK, Kaprio J, Khaw KT, Kuehnel B, Laitinen J, Lobbens S, Luan J, Mangino M, Maroteaux M, Matullo G, McCarthy MI, Mueller C, Navis G, Numans ME, Núñez A, Nyholt DR, Onland-Moret CN, Oostra BA, O'Reilly PF, Palkovits M, Penninx BW, Polidoro S, Pouta A, Prokopenko I, Ricceri F, Santos E, Smit JH, Soranzo N, Song K, Sovio U, Stumvoll M, Surakk I, Thorgeirsson TE, Thorsteinsdottir U, Troakes C, Tyrfingsson T, Tönjes A, Uiterwaal CS, Uitterlinden AG, van der Harst P, van der Schouw YT, Staehlin O, Vogelzangs N, Vollenweider P, Waeber G, Wareham NJ, Waterworth DM, Whitfield JB, Wichmann EH, Willemsen G, Witteman JC, Yuan X, Zhai G, Zhao JH, Zhang W, Martin NG, Metspalu A, Doering A, Scott J, Spector TD, Loos RJ, Boomsma DI, Mooser V, Peltonen L, Stefansson K, van Duijn CM, Vineis P, Sommer WH, Kooner JS, Spanagel R, Heberlein UA, Jarvelin MR, Elliott P. Genome-wide association and genetic functional studies identify autism susceptibility candidate 2 gene (AUTS2) in the regulation of alcohol consumption. Proc Natl Acad Sci U S A. 2011 Apr 26; 108(17):7119-24.
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  266. El Marroun H, Hudziak JJ, Tiemeier H, Creemers H, Steegers EA, Jaddoe VW, Hofman A, Verhulst FC, van den Brink W, Huizink AC. Intrauterine cannabis exposure leads to more aggressive behavior and attention problems in 18-month-old girls. Drug Alcohol Depend. 2011 Nov 1; 118(2-3):470-4.
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  267. Székely E, Tiemeier H, Arends LR, Jaddoe VW, Hofman A, Verhulst FC, Herba CM. Recognition of facial expressions of emotions by 3-year-olds. Emotion. 2011 Apr; 11(2):425-35.
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  268. Krijthe BP, Walter S, Newson RS, Hofman A, Hunink MG, Tiemeier H. Is positive affect associated with survival? A population-based study of elderly persons. Am J Epidemiol. 2011 Jun 1; 173(11):1298-307.
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  269. Demirkan A, Amin N, Isaacs A, Jarvelin MR, Whitfield JB, Wichmann HE, Kyvik KO, Rudan I, Gieger C, Hicks AA, Johansson Å, Hottenga JJ, Smith JJ, Wild SH, Pedersen NL, Willemsen G, Mangino M, Hayward C, Uitterlinden AG, Hofman A, Witteman J, Montgomery GW, Pietiläinen KH, Rantanen T, Kaprio J, Döring A, Pramstaller PP, Gyllensten U, de Geus EJ, Penninx BW, Wilson JF, Rivadeneria F, Magnusson PK, Boomsma DI, Spector T, Campbell H, Hoehne B, Martin NG, Oostra BA, McCarthy M, Peltonen-Palotie L, Aulchenko Y, Visscher PM, Ripatti S, Janssens AC, van Duijn CM. Genetic architecture of circulating lipid levels. Eur J Hum Genet. 2011 Jul; 19(7):813-9.
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  270. Ligthart L, de Vries B, Smith AV, Ikram MA, Amin N, Hottenga JJ, Koelewijn SC, Kattenberg VM, de Moor MH, Janssens AC, Aulchenko YS, Oostra BA, de Geus EJ, Smit JH, Zitman FG, Uitterlinden AG, Hofman A, Willemsen G, Nyholt DR, Montgomery GW, Terwindt GM, Gudnason V, Penninx BW, Breteler M, Ferrari MD, Launer LJ, van Duijn CM, van den Maagdenberg AM, Boomsma DI. Meta-analysis of genome-wide association for migraine in six population-based European cohorts. Eur J Hum Genet. 2011 Aug; 19(8):901-7.
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  271. de Jonge LL, van Osch-Gevers L, Willemsen SP, Steegers EA, Hofman A, Helbing WA, Jaddoe VW. Growth, obesity, and cardiac structures in early childhood: the Generation R Study. Hypertension. 2011 May; 57(5):934-40.
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  272. Ramdas WD, van Koolwijk LM, Lemij HG, Pasutto F, Cree AJ, Thorleifsson G, Janssen SF, Jacoline TB, Amin N, Rivadeneira F, Wolfs RC, Walters GB, Jonasson F, Weisschuh N, Mardin CY, Gibson J, Zegers RH, Hofman A, de Jong PT, Uitterlinden AG, Oostra BA, Thorsteinsdottir U, Gramer E, Welgen-Lüssen UC, Kirwan JF, Bergen AA, Reis A, Stefansson K, Lotery AJ, Vingerling JR, Jansonius NM, Klaver CC, van Duijn CM. Common genetic variants associated with open-angle glaucoma. Hum Mol Genet. 2011 Jun 15; 20(12):2464-71.
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  273. Teichert M, van Noord C, Uitterlinden AG, Hofman A, Buhre PN, De Smet PA, Straus S, Stricker BH, Visser LE. Proton pump inhibitors and the risk of overanticoagulation during acenocoumarol maintenance treatment. Br J Haematol. 2011 May; 153(3):379-85.
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  274. Newson RS, Boelen PA, Hek K, Hofman A, Tiemeier H. The prevalence and characteristics of complicated grief in older adults. J Affect Disord. 2011 Jul; 132(1-2):231-8.
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  275. Snijder CA, Brouwers MM, Jaddoe VW, Hofman A, Roeleveld N, Burdorf A. Occupational exposure to endocrine disruptors and time to pregnancy among couples in a large birth cohort study: the Generation R Study. Fertil Steril. 2011 May; 95(6):2067-72.
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  276. Schunkert H, König IR, Kathiresan S, Reilly MP, Assimes TL, Holm H, Preuss M, Stewart AF, Barbalic M, Gieger C, Absher D, Aherrahrou Z, Allayee H, Altshuler D, Anand SS, Andersen K, Anderson JL, Ardissino D, Ball SG, Balmforth AJ, Barnes TA, Becker DM, Becker LC, Berger K, Bis JC, Boekholdt SM, Boerwinkle E, Braund PS, Brown MJ, Burnett MS, Buysschaert I, Carlquist JF, Chen L, Cichon S, Codd V, Davies RW, Dedoussis G, Dehghan A, Demissie S, Devaney JM, Diemert P, Do R, Doering A, Eifert S, Mokhtari NE, Ellis SG, Elosua R, Engert JC, Epstein SE, de Faire U, Fischer M, Folsom AR, Freyer J, Gigante B, Girelli D, Gretarsdottir S, Gudnason V, Gulcher JR, Halperin E, Hammond N, Hazen SL, Hofman A, Horne BD, Illig T, Iribarren C, Jones GT, Jukema JW, Kaiser MA, Kaplan LM, Kastelein JJ, Khaw KT, Knowles JW, Kolovou G, Kong A, Laaksonen R, Lambrechts D, Leander K, Lettre G, Li M, Lieb W, Loley C, Lotery AJ, Mannucci PM, Maouche S, Martinelli N, McKeown PP, Meisinger C, Meitinger T, Melander O, Merlini PA, Mooser V, Morgan T, Mühleisen TW, Muhlestein JB, Münzel T, Musunuru K, Nahrstaedt J, Nelson CP, Nöthen MM, Olivieri O, Patel RS, Patterson CC, Peters A, Peyvandi F, Qu L, Quyyumi AA, Rader DJ, Rallidis LS, Rice C, Rosendaal FR, Rubin D, Salomaa V, Sampietro ML, Sandhu MS, Schadt E, Schäfer A, Schillert A, Schreiber S, Schrezenmeir J, Schwartz SM, Siscovick DS, Sivananthan M, Sivapalaratnam S, Smith A, Smith TB, Snoep JD, Soranzo N, Spertus JA, Stark K, Stirrups K, Stoll M, Tang WH, Tennstedt S, Thorgeirsson G, Thorleifsson G, Tomaszewski M, Uitterlinden AG, van Rij AM, Voight BF, Wareham NJ, Wells GA, Wichmann HE, Wild PS, Willenborg C, Witteman JC, Wright BJ, Ye S, Zeller T, Ziegler A, Cambien F, Goodall AH, Cupples LA, Quertermous T, März W, Hengstenberg C, Blankenberg S, Ouwehand WH, Hall AS, Deloukas P, Thompson JR, Stefansson K, Roberts R, Thorsteinsdottir U, O'Donnell CJ, McPherson R, Erdmann J, Samani NJ. Large-scale association analysis identifies 13 new susceptibility loci for coronary artery disease. Nat Genet. 2011 Apr; 43(4):333-8.
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  277. Fox ER, Young JH, Li Y, Dreisbach AW, Keating BJ, Musani SK, Liu K, Morrison AC, Ganesh S, Kutlar A, Ramachandran VS, Polak JF, Fabsitz RR, Dries DL, Farlow DN, Redline S, Adeyemo A, Hirschorn JN, Sun YV, Wyatt SB, Penman AD, Palmas W, Rotter JI, Townsend RR, Doumatey AP, Tayo BO, Mosley TH, Lyon HN, Kang SJ, Rotimi CN, Cooper RS, Franceschini N, Curb JD, Martin LW, Eaton CB, Kardia SL, Taylor HA, Caulfield MJ, Ehret GB, Johnson T, Chakravarti A, Zhu X, Levy D. Association of genetic variation with systolic and diastolic blood pressure among African Americans: the Candidate Gene Association Resource study. Hum Mol Genet. 2011 Jun 1; 20(11):2273-84.
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  278. Medici M, van der Deure WM, Verbiest M, Vermeulen SH, Hansen PS, Kiemeney LA, Hermus AR, Breteler MM, Hofman A, Hegedüs L, Kyvik KO, den Heijer M, Uitterlinden AG, Visser TJ, Peeters RP. A large-scale association analysis of 68 thyroid hormone pathway genes with serum TSH and FT4 levels. Eur J Endocrinol. 2011 May; 164(5):781-8.
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  279. IJsselstijn L, Dekker LJ, Koudstaal PJ, Hofman A, Sillevis Smitt PA, Breteler MM, Luider TM. Serum clusterin levels are not increased in presymptomatic Alzheimer's disease. J Proteome Res. 2011 Apr 1; 10(4):2006-10.
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  280. Direk N, Newson RS, Hofman A, Kirschbaum C, Tiemeier H. Short and long-term effects of smoking on cortisol in older adults. Int J Psychophysiol. 2011 May; 80(2):157-60.
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  281. Ramdas WD, Wolfs RC, Hofman A, de Jong PT, Vingerling JR, Jansonius NM. Lifestyle and risk of developing open-angle glaucoma: the Rotterdam study. Arch Ophthalmol. 2011 Jun; 129(6):767-72.
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  282. Velders FP, Kuningas M, Kumari M, Dekker MJ, Uitterlinden AG, Kirschbaum C, Hek K, Hofman A, Verhulst FC, Kivimaki M, Van Duijn CM, Walker BR, Tiemeier H. Genetics of cortisol secretion and depressive symptoms: a candidate gene and genome wide association approach. Psychoneuroendocrinology. 2011 Aug; 36(7):1053-61.
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  283. Wolff NJ, Darlington AS, Hunfeld JA, Tharner A, Van Ijzendoorn MH, Bakermans-Kranenburg MJ, Moll HA, Jaddoe VW, Hofman A, Verhulst FC, Passchier J, Tiemeier H. The influence of attachment and temperament on venipuncture distress in 14-month-old infants: the Generation R Study. Infant Behav Dev. 2011 Apr; 34(2):293-302.
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  284. Poels MM, Ikram MA, van der Lugt A, Hofman A, Krestin GP, Breteler MM, Vernooij MW. Incidence of cerebral microbleeds in the general population: the Rotterdam Scan Study. Stroke. 2011 Mar; 42(3):656-61.
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  285. Mook-Kanamori DO, Marsh JA, Warrington NM, Taal HR, Newnham JP, Beilin LJ, Lye SJ, Palmer LJ, Hofman A, Steegers EA, Pennell CE, Jaddoe VW. Variants near CCNL1/LEKR1 and in ADCY5 and fetal growth characteristics in different trimesters. J Clin Endocrinol Metab. 2011 May; 96(5):E810-5.
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  286. Dehghan A, Dupuis J, Barbalic M, Bis JC, Eiriksdottir G, Lu C, Pellikka N, Wallaschofski H, Kettunen J, Henneman P, Baumert J, Strachan DP, Fuchsberger C, Vitart V, Wilson JF, Paré G, Naitza S, Rudock ME, Surakka I, de Geus EJ, Alizadeh BZ, Guralnik J, Shuldiner A, Tanaka T, Zee RY, Schnabel RB, Nambi V, Kavousi M, Ripatti S, Nauck M, Smith NL, Smith AV, Sundvall J, Scheet P, Liu Y, Ruokonen A, Rose LM, Larson MG, Hoogeveen RC, Freimer NB, Teumer A, Tracy RP, Launer LJ, Buring JE, Yamamoto JF, Folsom AR, Sijbrands EJ, Pankow J, Elliott P, Keaney JF, Sun W, Sarin AP, Fontes JD, Badola S, Astor BC, Hofman A, Pouta A, Werdan K, Greiser KH, Kuss O, Meyer zu Schwabedissen HE, Thiery J, Jamshidi Y, Nolte IM, Soranzo N, Spector TD, Völzke H, Parker AN, Aspelund T, Bates D, Young L, Tsui K, Siscovick DS, Guo X, Rotter JI, Uda M, Schlessinger D, Rudan I, Hicks AA, Penninx BW, Thorand B, Gieger C, Coresh J, Willemsen G, Harris TB, Uitterlinden AG, Järvelin MR, Rice K, Radke D, Salomaa V, Willems van Dijk K, Boerwinkle E, Vasan RS, Ferrucci L, Gibson QD, Bandinelli S, Snieder H, Boomsma DI, Xiao X, Campbell H, Hayward C, Pramstaller PP, van Duijn CM, Peltonen L, Psaty BM, Gudnason V, Ridker PM, Homuth G, Koenig W, Ballantyne CM, Witteman JC, Benjamin EJ, Perola M, Chasman DI. Meta-analysis of genome-wide association studies in >80 000 subjects identifies multiple loci for C-reactive protein levels. Circulation. 2011 Feb 22; 123(7):731-8.
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  287. El Barzouhi A, Elias-Smale S, Dehghan A, Vliegenthart-Proença R, Oudkerk M, Hofman A, Witteman JC. Renal function is related to severity of coronary artery calcification in elderly persons: the Rotterdam study. PLoS One. 2011; 6(2):e16738.
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  288. Luijendijk HJ, van den Berg JF, Hofman A, Tiemeier H, Stricker BH. ß-blockers and the risk of incident depression in the elderly. J Clin Psychopharmacol. 2011 Feb; 31(1):45-50.
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  289. Ay L, Jaddoe VW, Hofman A, Moll HA, Raat H, Steegers EA, Hokken-Koelega AC. Foetal and postnatal growth and bone mass at 6 months: the Generation R Study. Clin Endocrinol (Oxf). 2011 Feb; 74(2):181-90.
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  290. Durmus B, van Rossem L, Duijts L, Arends LR, Raat H, Moll HA, Hofman A, Steegers EA, Jaddoe VW. Breast-feeding and growth in children until the age of 3 years: the Generation R Study. Br J Nutr. 2011 Jun; 105(11):1704-11.
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  291. Lebon A, Verkaik NJ, Labout JA, de Vogel CP, Hooijkaas H, Verbrugh HA, van Wamel WJ, Jaddoe VW, Hofman A, Hermans PW, Ma J, Mitchell TJ, Moll HA, van Belkum A. Natural antibodies against several pneumococcal virulence proteins in children during the pre-pneumococcal-vaccine era: the generation R study. Infect Immun. 2011 Apr; 79(4):1680-7.
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  292. Heppe DH, Steegers EA, Timmermans S, Breeijen Hd, Tiemeier H, Hofman A, Jaddoe VW. Maternal fish consumption, fetal growth and the risks of neonatal complications: the Generation R Study. Br J Nutr. 2011 Mar; 105(6):938-49.
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  293. Jansen PW, Saridjan NS, Hofman A, Jaddoe VW, Verhulst FC, Tiemeier H. Does disturbed sleeping precede symptoms of anxiety or depression in toddlers? The generation R study. Psychosom Med. 2011 Apr; 73(3):242-9.
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  294. Simón-Sánchez J, van Hilten JJ, van de Warrenburg B, Post B, Berendse HW, Arepalli S, Hernandez DG, de Bie RM, Velseboer D, Scheffer H, Bloem B, van Dijk KD, Rivadeneira F, Hofman A, Uitterlinden AG, Rizzu P, Bochdanovits Z, Singleton AB, Heutink P. Genome-wide association study confirms extant PD risk loci among the Dutch. Eur J Hum Genet. 2011 Jun; 19(6):655-61.
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  295. Durmus B, Ay L, Hokken-Koelega AC, Raat H, Hofman A, Steegers EA, Jaddoe VW. Maternal smoking during pregnancy and subcutaneous fat mass in early childhood. The Generation R Study. Eur J Epidemiol. 2011 Apr; 26(4):295-304.
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  296. Kuningas M, Altmäe S, Uitterlinden AG, Hofman A, van Duijn CM, Tiemeier H. The relationship between fertility and lifespan in humans. Age (Dordr). 2011 Dec; 33(4):615-22.
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  297. van den Hooven EH, de Kluizenaar Y, Pierik FH, Hofman A, van Ratingen SW, Zandveld PY, Mackenbach JP, Steegers EA, Miedema HM, Jaddoe VW. Air pollution, blood pressure, and the risk of hypertensive complications during pregnancy: the generation R study. Hypertension. 2011 Mar; 57(3):406-12.
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  298. Timmermans S, Bonsel GJ, Steegers-Theunissen RP, Mackenbach JP, Steyerberg EW, Raat H, Verbrugh HA, Tiemeier HW, Hofman A, Birnie E, Looman CW, Jaddoe VW, Steegers EA. Individual accumulation of heterogeneous risks explains perinatal inequalities within deprived neighbourhoods. Eur J Epidemiol. 2011 Feb; 26(2):165-80.
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  299. Schrijvers EM, Direk N, Koudstaal PJ, Kirschbaum C, Hofman A, Tiemeier H, Breteler MM. Associations of serum cortisol with cognitive function and dementia: the Rotterdam Study. J Alzheimers Dis. 2011; 25(4):671-7.
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  300. Broer L, Ikram MA, Schuur M, DeStefano AL, Bis JC, Liu F, Rivadeneira F, Uitterlinden AG, Beiser AS, Longstreth WT, Hofman A, Aulchenko Y, Seshadri S, Fitzpatrick AL, Oostra BA, Breteler MM, van Duijn CM. Association of HSP70 and its co-chaperones with Alzheimer's disease. J Alzheimers Dis. 2011; 25(1):93-102.
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  301. Tharner A, Herba CM, Luijk MP, van Ijzendoorn MH, Bakermans-Kranenburg MJ, Govaert PP, Roza SJ, Jaddoe VW, Hofman A, Verhulst FC, Tiemeier H. Subcortical structures and the neurobiology of infant attachment disorganization: a longitudinal ultrasound imaging study. Soc Neurosci. 2011; 6(4):336-47.
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  302. Teichert M, Eijgelsheim M, Uitterlinden AG, Buhre PN, Hofman A, De Smet PA, Visser LE, Stricker BH. Dependency of phenprocoumon dosage on polymorphisms in the VKORC1, CYP2C9, and CYP4F2 genes. Pharmacogenet Genomics. 2011 Jan; 21(1):26-34.
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  303. Bakker R, Steegers EA, Raat H, Hofman A, Jaddoe VW. Maternal caffeine intake, blood pressure, and the risk of hypertensive complications during pregnancy. The Generation R Study. Am J Hypertens. 2011 Apr; 24(4):421-8.
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  304. Geelhoed JJ, van Duijn C, van Osch-Gevers L, Steegers EA, Hofman A, Helbing WA, Jaddoe VW. Glucocorticoid receptor-9beta polymorphism is associated with systolic blood pressure and heart growth during early childhood. The Generation R Study. Early Hum Dev. 2011 Feb; 87(2):97-102.
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  305. Pluess M, Velders FP, Belsky J, van IJzendoorn MH, Bakermans-Kranenburg MJ, Jaddoe VW, Hofman A, Arp PP, Verhulst FC, Tiemeier H. Serotonin transporter polymorphism moderates effects of prenatal maternal anxiety on infant negative emotionality. Biol Psychiatry. 2011 Mar 15; 69(6):520-5.
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  306. Elks CE, Perry JR, Sulem P, Chasman DI, Franceschini N, He C, Lunetta KL, Visser JA, Byrne EM, Cousminer DL, Gudbjartsson DF, Esko T, Feenstra B, Hottenga JJ, Koller DL, Kutalik Z, Lin P, Mangino M, Marongiu M, McArdle PF, Smith AV, Stolk L, van Wingerden SH, Zhao JH, Albrecht E, Corre T, Ingelsson E, Hayward C, Magnusson PK, Smith EN, Ulivi S, Warrington NM, Zgaga L, Alavere H, Amin N, Aspelund T, Bandinelli S, Barroso I, Berenson GS, Bergmann S, Blackburn H, Boerwinkle E, Buring JE, Busonero F, Campbell H, Chanock SJ, Chen W, Cornelis MC, Couper D, Coviello AD, d'Adamo P, de Faire U, de Geus EJ, Deloukas P, Döring A, Smith GD, Easton DF, Eiriksdottir G, Emilsson V, Eriksson J, Ferrucci L, Folsom AR, Foroud T, Garcia M, Gasparini P, Geller F, Gieger C, Gudnason V, Hall P, Hankinson SE, Ferreli L, Heath AC, Hernandez DG, Hofman A, Hu FB, Illig T, Järvelin MR, Johnson AD, Karasik D, Khaw KT, Kiel DP, Kilpeläinen TO, Kolcic I, Kraft P, Launer LJ, Laven JS, Li S, Liu J, Levy D, Martin NG, McArdle WL, Melbye M, Mooser V, Murray JC, Murray SS, Nalls MA, Navarro P, Nelis M, Ness AR, Northstone K, Oostra BA, Peacock M, Palmer LJ, Palotie A, Paré G, Parker AN, Pedersen NL, Peltonen L, Pennell CE, Pharoah P, Polasek O, Plump AS, Pouta A, Porcu E, Rafnar T, Rice JP, Ring SM, Rivadeneira F, Rudan I, Sala C, Salomaa V, Sanna S, Schlessinger D, Schork NJ, Scuteri A, Segrè AV, Shuldiner AR, Soranzo N, Sovio U, Srinivasan SR, Strachan DP, Tammesoo ML, Tikkanen E, Toniolo D, Tsui K, Tryggvadottir L, Tyrer J, Uda M, van Dam RM, van Meurs JB, Vollenweider P, Waeber G, Wareham NJ, Waterworth DM, Weedon MN, Wichmann HE, Willemsen G, Wilson JF, Wright AF, Young L, Zhai G, Zhuang WV, Bierut LJ, Boomsma DI, Boyd HA, Crisponi L, Demerath EW, van Duijn CM, Econs MJ, Harris TB, Hunter DJ, Loos RJ, Metspalu A, Montgomery GW, Ridker PM, Spector TD, Streeten EA, Stefansson K, Thorsteinsdottir U, Uitterlinden AG, Widen E, Murabito JM, Ong KK, Murray A. Thirty new loci for age at menarche identified by a meta-analysis of genome-wide association studies. Nat Genet. 2010 Dec; 42(12):1077-85.
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  307. Altorf-van der Kuil W, Engberink MF, van Rooij FJ, Hofman A, van't Veer P, Witteman JC, Geleijnse JM. Dietary protein and risk of hypertension in a Dutch older population: the Rotterdam study. J Hypertens. 2010 Dec; 28(12):2394-400.
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  308. Hofman A. New studies, technology, and the progress of epidemiology. Eur J Epidemiol. 2010 Dec; 25(12):851-4.
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  309. van den Hondel KE, Eijgelsheim M, Ruiter R, Witteman JC, Hofman A, Stricker BH. Effect of short-term NSAID use on echocardiographic parameters in elderly people: a population-based cohort study. Heart. 2011 Apr; 97(7):540-3.
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  310. Lebon A, Verkaik NJ, de Vogel CP, Hooijkaas H, Verbrugh HA, van Wamel WJ, Jaddoe VW, Hofman A, Hermans PW, Mitchell TJ, Moll HA, van Belkum A. The inverse correlation between Staphylococcus aureus and Streptococcus pneumoniae colonization in infants is not explained by differences in serum antibody levels in the Generation R Study. Clin Vaccine Immunol. 2011 Jan; 18(1):180-3.
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  311. Kerkhof HJ, Meulenbelt I, Carr A, Gonzalez A, Hart D, Hofman A, Kloppenburg M, Lane NE, Loughlin J, Nevitt MC, Pols HA, Rivadeneira F, Slagboom EP, Spector TD, Stolk L, Tsezou A, Uitterlinden AG, Valdes AM, van Meurs JB. Common genetic variation in the Estrogen Receptor Beta (ESR2) gene and osteoarthritis: results of a meta-analysis. BMC Med Genet. 2010; 11:164.
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  312. Sotoodehnia N, Isaacs A, de Bakker PI, Dörr M, Newton-Cheh C, Nolte IM, van der Harst P, Müller M, Eijgelsheim M, Alonso A, Hicks AA, Padmanabhan S, Hayward C, Smith AV, Polasek O, Giovannone S, Fu J, Magnani JW, Marciante KD, Pfeufer A, Gharib SA, Teumer A, Li M, Bis JC, Rivadeneira F, Aspelund T, Köttgen A, Johnson T, Rice K, Sie MP, Wang YA, Klopp N, Fuchsberger C, Wild SH, Mateo Leach I, Estrada K, Völker U, Wright AF, Asselbergs FW, Qu J, Chakravarti A, Sinner MF, Kors JA, Petersmann A, Harris TB, Soliman EZ, Munroe PB, Psaty BM, Oostra BA, Cupples LA, Perz S, de Boer RA, Uitterlinden AG, Völzke H, Spector TD, Liu FY, Boerwinkle E, Dominiczak AF, Rotter JI, van Herpen G, Levy D, Wichmann HE, van Gilst WH, Witteman JC, Kroemer HK, Kao WH, Heckbert SR, Meitinger T, Hofman A, Campbell H, Folsom AR, van Veldhuisen DJ, Schwienbacher C, O'Donnell CJ, Volpato CB, Caulfield MJ, Connell JM, Launer L, Lu X, Franke L, Fehrmann RS, te Meerman G, Groen HJ, Weersma RK, van den Berg LH, Wijmenga C, Ophoff RA, Navis G, Rudan I, Snieder H, Wilson JF, Pramstaller PP, Siscovick DS, Wang TJ, Gudnason V, van Duijn CM, Felix SB, Fishman GI, Jamshidi Y, Stricker BH, Samani NJ, Kääb S, Arking DE. Common variants in 22 loci are associated with QRS duration and cardiac ventricular conduction. Nat Genet. 2010 Dec; 42(12):1068-76.
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  313. Evangelou E, Valdes AM, Kerkhof HJ, Styrkarsdottir U, Zhu Y, Meulenbelt I, Lories RJ, Karassa FB, Tylzanowski P, Bos SD, Akune T, Arden NK, Carr A, Chapman K, Cupples LA, Dai J, Deloukas P, Doherty M, Doherty S, Engstrom G, Gonzalez A, Halldorsson BV, Hammond CL, Hart DJ, Helgadottir H, Hofman A, Ikegawa S, Ingvarsson T, Jiang Q, Jonsson H, Kaprio J, Kawaguchi H, Kisand K, Kloppenburg M, Kujala UM, Lohmander LS, Loughlin J, Luyten FP, Mabuchi A, McCaskie A, Nakajima M, Nilsson PM, Nishida N, Ollier WE, Panoutsopoulou K, van de Putte T, Ralston SH, Rivadeneira F, Saarela J, Schulte-Merker S, Shi D, Slagboom PE, Sudo A, Tamm A, Tamm A, Thorleifsson G, Thorsteinsdottir U, Tsezou A, Wallis GA, Wilkinson JM, Yoshimura N, Zeggini E, Zhai G, Zhang F, Jonsdottir I, Uitterlinden AG, Felson DT, van Meurs JB, Stefansson K, Ioannidis JP, Spector TD. Meta-analysis of genome-wide association studies confirms a susceptibility locus for knee osteoarthritis on chromosome 7q22. Ann Rheum Dis. 2011 Feb; 70(2):349-55.
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  314. Ramdas WD, Amin N, van Koolwijk LM, Janssens AC, Demirkan A, de Jong PT, Aulchenko YS, Wolfs RC, Hofman A, Rivadeneira F, Uitterlinden AG, Oostra BA, Lemij HG, Klaver CC, Vingerling JR, Jansonius NM, van Duijn CM. Genetic architecture of open angle glaucoma and related determinants. J Med Genet. 2011 Mar; 48(3):190-6.
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  315. Newson RS, Hek K, Luijendijk HJ, Hofman A, Witteman JC, Tiemeier H. Atherosclerosis and incident depression in late life. Arch Gen Psychiatry. 2010 Nov; 67(11):1144-51.
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  316. Bakker R, Steegers EA, Mackenbach JP, Hofman A, Jaddoe VW. Maternal smoking and blood pressure in different trimesters of pregnancy: the Generation R study. J Hypertens. 2010 Nov; 28(11):2210-8.
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  317. Jansen PW, Raat H, Mackenbach JP, Jaddoe VW, Hofman A, van Oort FV, Verhulst FC, Tiemeier H. National origin and behavioural problems of toddlers: the role of family risk factors and maternal immigration characteristics. J Abnorm Child Psychol. 2010 Nov; 38(8):1151-64.
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  318. Baas DC, Despriet DD, Gorgels TG, Bergeron-Sawitzke J, Uitterlinden AG, Hofman A, van Duijn CM, Merriam JE, Smith RT, Barile GR, ten Brink JB, Vingerling JR, Klaver CC, Allikmets R, Dean M, Bergen AA. The ERCC6 gene and age-related macular degeneration. PLoS One. 2010; 5(11):e13786.
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  319. Visser AM, Jaddoe VW, Arends LR, Tiemeier H, Hofman A, Moll HA, Steegers EA, Breteler MM, Arts WF. Paroxysmal disorders in infancy and their risk factors in a population-based cohort: the Generation R Study. Dev Med Child Neurol. 2010 Nov; 52(11):1014-20.
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  320. Ikram MK, Sim X, Xueling S, Jensen RA, Cotch MF, Hewitt AW, Ikram MA, Wang JJ, Klein R, Klein BE, Breteler MM, Cheung N, Liew G, Mitchell P, Uitterlinden AG, Rivadeneira F, Hofman A, de Jong PT, van Duijn CM, Kao L, Cheng CY, Smith AV, Glazer NL, Lumley T, McKnight B, Psaty BM, Jonasson F, Eiriksdottir G, Aspelund T, Harris TB, Launer LJ, Taylor KD, Li X, Iyengar SK, Xi Q, Sivakumaran TA, Mackey DA, Macgregor S, Martin NG, Young TL, Bis JC, Wiggins KL, Heckbert SR, Hammond CJ, Andrew T, Fahy S, Attia J, Holliday EG, Scott RJ, Islam FM, Rotter JI, McAuley AK, Boerwinkle E, Tai ES, Gudnason V, Siscovick DS, Vingerling JR, Wong TY. Four novel Loci (19q13, 6q24, 12q24, and 5q14) influence the microcirculation in vivo. PLoS Genet. 2010 Oct; 6(10):e1001184.
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  321. Raat H, van Rossem L, Jaddoe VW, Landgraf JM, Feeny D, Moll HA, Hofman A, Mackenbach JP. The Generation R study: a candidate gene study and genome-wide association study (GWAS) on health-related quality of life (HRQOL) of mothers and young children. Qual Life Res. 2010 Dec; 19(10):1439-46.
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  322. Wieberdink RG, Ikram MK, Koudstaal PJ, Hofman A, Vingerling JR, Breteler MM. Retinal vascular calibers and the risk of intracerebral hemorrhage and cerebral infarction: the Rotterdam Study. Stroke. 2010 Dec; 41(12):2757-61.
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  323. Jaddoe VW, van Duijn CM, van der Heijden AJ, Mackenbach JP, Moll HA, Steegers EA, Tiemeier H, Uitterlinden AG, Verhulst FC, Hofman A. The Generation R Study: design and cohort update 2010. Eur J Epidemiol. 2010 Nov; 25(11):823-41.
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  324. Henrichs J, Rescorla L, Schenk JJ, Schmidt HG, Jaddoe VW, Hofman A, Raat H, Verhulst FC, Tiemeier H. Examining continuity of early expressive vocabulary development: the generation R study. J Speech Lang Hear Res. 2011 Jun; 54(3):854-69.
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  325. Elias-Smale SE, Proença RV, Koller MT, Kavousi M, van Rooij FJ, Hunink MG, Steyerberg EW, Hofman A, Oudkerk M, Witteman JC. Coronary calcium score improves classification of coronary heart disease risk in the elderly: the Rotterdam study. J Am Coll Cardiol. 2010 Oct 19; 56(17):1407-14.
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  347. Meyer TE, Verwoert GC, Hwang SJ, Glazer NL, Smith AV, van Rooij FJ, Ehret GB, Boerwinkle E, Felix JF, Leak TS, Harris TB, Yang Q, Dehghan A, Aspelund T, Katz R, Homuth G, Kocher T, Rettig R, Ried JS, Gieger C, Prucha H, Pfeufer A, Meitinger T, Coresh J, Hofman A, Sarnak MJ, Chen YD, Uitterlinden AG, Chakravarti A, Psaty BM, van Duijn CM, Kao WH, Witteman JC, Gudnason V, Siscovick DS, Fox CS, Köttgen A. Genome-wide association studies of serum magnesium, potassium, and sodium concentrations identify six Loci influencing serum magnesium levels. PLoS Genet. 2010 Aug; 6(8).
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  348. Blauw HM, Al-Chalabi A, Andersen PM, van Vught PW, Diekstra FP, van Es MA, Saris CG, Groen EJ, van Rheenen W, Koppers M, Van't Slot R, Strengman E, Estrada K, Rivadeneira F, Hofman A, Uitterlinden AG, Kiemeney LA, Vermeulen SH, Birve A, Waibel S, Meyer T, Cronin S, McLaughlin RL, Hardiman O, Sapp PC, Tobin MD, Wain LV, Tomik B, Slowik A, Lemmens R, Rujescu D, Schulte C, Gasser T, Brown RH, Landers JE, Robberecht W, Ludolph AC, Ophoff RA, Veldink JH, van den Berg LH. A large genome scan for rare CNVs in amyotrophic lateral sclerosis. Hum Mol Genet. 2010 Oct 15; 19(20):4091-9.
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  349. Becker ML, Visser LE, van Schaik RH, Hofman A, Uitterlinden AG, Stricker BH. OCT1 polymorphism is associated with response and survival time in anti-Parkinsonian drug users. Neurogenetics. 2011 Feb; 12(1):79-82.
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  350. Kiiski V, de Vries E, Flohil SC, Bijl MJ, Hofman A, Stricker BH, Nijsten T. Risk factors for single and multiple basal cell carcinomas. Arch Dermatol. 2010 Aug; 146(8):848-55.
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  351. Siemes C, Visser LE, de Jong FH, Coebergh JW, Uitterlinden AG, Hofman A, Stricker BH, van Schaik RH. Cytochrome P450 3A gene variation, steroid hormone serum levels and prostate cancer--The Rotterdam Study. Steroids. 2010 Dec; 75(12):1024-32.
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  352. Vergeer M, Boekholdt SM, Sandhu MS, Ricketts SL, Wareham NJ, Brown MJ, de Faire U, Leander K, Gigante B, Kavousi M, Hofman A, Uitterlinden AG, van Duijn CM, Witteman JC, Jukema JW, Schadt EE, van der Schoot E, Kastelein JJ, Khaw KT, Dullaart RP, van Tol A, Trip MD, Dallinga-Thie GM. Genetic variation at the phospholipid transfer protein locus affects its activity and high-density lipoprotein size and is a novel marker of cardiovascular disease susceptibility. Circulation. 2010 Aug 3; 122(5):470-7.
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  353. Pardo Silva MC, Njajou OT, Alizadeh BZ, Hofman A, Witteman JC, van Duijn CM, Janssens AC. HFE gene mutations increase the risk of coronary heart disease in women. Eur J Epidemiol. 2010 Sep; 25(9):643-9.
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  354. Eijgelsheim M, Newton-Cheh C, Sotoodehnia N, de Bakker PI, Müller M, Morrison AC, Smith AV, Isaacs A, Sanna S, Dörr M, Navarro P, Fuchsberger C, Nolte IM, de Geus EJ, Estrada K, Hwang SJ, Bis JC, Rückert IM, Alonso A, Launer LJ, Hottenga JJ, Rivadeneira F, Noseworthy PA, Rice KM, Perz S, Arking DE, Spector TD, Kors JA, Aulchenko YS, Tarasov KV, Homuth G, Wild SH, Marroni F, Gieger C, Licht CM, Prineas RJ, Hofman A, Rotter JI, Hicks AA, Ernst F, Najjar SS, Wright AF, Peters A, Fox ER, Oostra BA, Kroemer HK, Couper D, Völzke H, Campbell H, Meitinger T, Uda M, Witteman JC, Psaty BM, Wichmann HE, Harris TB, Kääb S, Siscovick DS, Jamshidi Y, Uitterlinden AG, Folsom AR, Larson MG, Wilson JF, Penninx BW, Snieder H, Pramstaller PP, van Duijn CM, Lakatta EG, Felix SB, Gudnason V, Pfeufer A, Heckbert SR, Stricker BH, Boerwinkle E, O'Donnell CJ. Genome-wide association analysis identifies multiple loci related to resting heart rate. Hum Mol Genet. 2010 Oct 1; 19(19):3885-94.
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  355. Cents RA, Tiemeier H, Luijk MP, Jaddoe VW, Hofman A, Verhulst FC, Lambregtse-van den Berg MP. Grandparental anxiety and depression predict young children's internalizing and externalizing problems: the generation R study. J Affect Disord. 2011 Jan; 128(1-2):95-105.
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  356. van Rossem L, Silva LM, Hokken-Koelega A, Arends LR, Moll HA, Jaddoe VW, Hofman A, Mackenbach JP, Raat H. Socioeconomic status is not inversely associated with overweight in preschool children. J Pediatr. 2010 Dec; 157(6):929-935.e1.
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  357. Psaty BM, Hofman A. Genome-wide association studies and large-scale collaborations in epidemiology. Eur J Epidemiol. 2010 Aug; 25(8):525-9.
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  358. de Jonge LL, van Osch-Gevers L, Geelhoed JJ, Hofman A, Steegers EA, Helbing WA, Jaddoe VW. Breastfeeding is not associated with left cardiac structures and blood pressure during the first two years of life. The Generation R Study. Early Hum Dev. 2010 Aug; 86(8):463-8.
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  359. Luijk MP, Saridjan N, Tharner A, van Ijzendoorn MH, Bakermans-Kranenburg MJ, Jaddoe VW, Hofman A, Verhulst FC, Tiemeier H. Attachment, depression, and cortisol: Deviant patterns in insecure-resistant and disorganized infants. Dev Psychobiol. 2010 Jul; 52(5):441-52.
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  360. Voight BF, Scott LJ, Steinthorsdottir V, Morris AP, Dina C, Welch RP, Zeggini E, Huth C, Aulchenko YS, Thorleifsson G, McCulloch LJ, Ferreira T, Grallert H, Amin N, Wu G, Willer CJ, Raychaudhuri S, McCarroll SA, Langenberg C, Hofmann OM, Dupuis J, Qi L, Segrè AV, van Hoek M, Navarro P, Ardlie K, Balkau B, Benediktsson R, Bennett AJ, Blagieva R, Boerwinkle E, Bonnycastle LL, Bengtsson Boström K, Bravenboer B, Bumpstead S, Burtt NP, Charpentier G, Chines PS, Cornelis M, Couper DJ, Crawford G, Doney AS, Elliott KS, Elliott AL, Erdos MR, Fox CS, Franklin CS, Ganser M, Gieger C, Grarup N, Green T, Griffin S, Groves CJ, Guiducci C, Hadjadj S, Hassanali N, Herder C, Isomaa B, Jackson AU, Johnson PR, Jørgensen T, Kao WH, Klopp N, Kong A, Kraft P, Kuusisto J, Lauritzen T, Li M, Lieverse A, Lindgren CM, Lyssenko V, Marre M, Meitinger T, Midthjell K, Morken MA, Narisu N, Nilsson P, Owen KR, Payne F, Perry JR, Petersen AK, Platou C, Proença C, Prokopenko I, Rathmann W, Rayner NW, Robertson NR, Rocheleau G, Roden M, Sampson MJ, Saxena R, Shields BM, Shrader P, Sigurdsson G, Sparsø T, Strassburger K, Stringham HM, Sun Q, Swift AJ, Thorand B, Tichet J, Tuomi T, van Dam RM, van Haeften TW, van Herpt T, van Vliet-Ostaptchouk JV, Walters GB, Weedon MN, Wijmenga C, Witteman J, Bergman RN, Cauchi S, Collins FS, Gloyn AL, Gyllensten U, Hansen T, Hide WA, Hitman GA, Hofman A, Hunter DJ, Hveem K, Laakso M, Mohlke KL, Morris AD, Palmer CN, Pramstaller PP, Rudan I, Sijbrands E, Stein LD, Tuomilehto J, Uitterlinden A, Walker M, Wareham NJ, Watanabe RM, Abecasis GR, Boehm BO, Campbell H, Daly MJ, Hattersley AT, Hu FB, Meigs JB, Pankow JS, Pedersen O, Wichmann HE, Barroso I, Florez JC, Frayling TM, Groop L, Sladek R, Thorsteinsdottir U, Wilson JF, Illig T, Froguel P, van Duijn CM, Stefansson K, Altshuler D, Boehnke M, McCarthy MI. Twelve type 2 diabetes susceptibility loci identified through large-scale association analysis. Nat Genet. 2010 Jul; 42(7):579-89.
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  361. Devore EE, Grodstein F, van Rooij FJ, Hofman A, Stampfer MJ, Witteman JC, Breteler MM. Dietary antioxidants and long-term risk of dementia. Arch Neurol. 2010 Jul; 67(7):819-25.
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  362. Rodenburg EM, Visser LE, Danser AH, Hofman A, van Noord C, Witteman JC, Uitterlinden AG, Stricker BH. Genetic variance in CYP2C8 and increased risk of myocardial infarction. Pharmacogenet Genomics. 2010 Jul; 20(7):426-34.
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  363. Elias-Smale SE, Odink AE, Wieberdink RG, Hofman A, Hunink MG, Krestin GP, Koudstaal PJ, Breteler MM, van der Lugt A, Witteman JC. Carotid, aortic arch and coronary calcification are related to history of stroke: the Rotterdam Study. Atherosclerosis. 2010 Oct; 212(2):656-60.
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  364. Czudowska MA, Ramdas WD, Wolfs RC, Hofman A, De Jong PT, Vingerling JR, Jansonius NM. Incidence of glaucomatous visual field loss: a ten-year follow-up from the Rotterdam Study. Ophthalmology. 2010 Sep; 117(9):1705-12.
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  365. Duijts L, Jaddoe VW, Hofman A, Moll HA. Prolonged and exclusive breastfeeding reduces the risk of infectious diseases in infancy. Pediatrics. 2010 Jul; 126(1):e18-25.
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  366. Mihaescu R, van Zitteren M, van Hoek M, Sijbrands EJ, Uitterlinden AG, Witteman JC, Hofman A, Hunink MG, van Duijn CM, Janssens AC. Improvement of risk prediction by genomic profiling: reclassification measures versus the area under the receiver operating characteristic curve. Am J Epidemiol. 2010 Aug 1; 172(3):353-61.
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  367. Kestenbaum B, Glazer NL, Köttgen A, Felix JF, Hwang SJ, Liu Y, Lohman K, Kritchevsky SB, Hausman DB, Petersen AK, Gieger C, Ried JS, Meitinger T, Strom TM, Wichmann HE, Campbell H, Hayward C, Rudan I, de Boer IH, Psaty BM, Rice KM, Chen YD, Li M, Arking DE, Boerwinkle E, Coresh J, Yang Q, Levy D, van Rooij FJ, Dehghan A, Rivadeneira F, Uitterlinden AG, Hofman A, van Duijn CM, Shlipak MG, Kao WH, Witteman JC, Siscovick DS, Fox CS. Common genetic variants associate with serum phosphorus concentration. J Am Soc Nephrol. 2010 Jul; 21(7):1223-32.
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  368. Hsu YH, Zillikens MC, Wilson SG, Farber CR, Demissie S, Soranzo N, Bianchi EN, Grundberg E, Liang L, Richards JB, Estrada K, Zhou Y, van Nas A, Moffatt MF, Zhai G, Hofman A, van Meurs JB, Pols HA, Price RI, Nilsson O, Pastinen T, Cupples LA, Lusis AJ, Schadt EE, Ferrari S, Uitterlinden AG, Rivadeneira F, Spector TD, Karasik D, Kiel DP. An integration of genome-wide association study and gene expression profiling to prioritize the discovery of novel susceptibility Loci for osteoporosis-related traits. PLoS Genet. 2010 Jun; 6(6):e1000977.
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  369. Ramdas WD, van Koolwijk LM, Ikram MK, Jansonius NM, de Jong PT, Bergen AA, Isaacs A, Amin N, Aulchenko YS, Wolfs RC, Hofman A, Rivadeneira F, Oostra BA, Uitterlinden AG, Hysi P, Hammond CJ, Lemij HG, Vingerling JR, Klaver CC, van Duijn CM. A genome-wide association study of optic disc parameters. PLoS Genet. 2010 Jun; 6(6):e1000978.
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  370. Wang TJ, Zhang F, Richards JB, Kestenbaum B, van Meurs JB, Berry D, Kiel DP, Streeten EA, Ohlsson C, Koller DL, Peltonen L, Cooper JD, O'Reilly PF, Houston DK, Glazer NL, Vandenput L, Peacock M, Shi J, Rivadeneira F, McCarthy MI, Anneli P, de Boer IH, Mangino M, Kato B, Smyth DJ, Booth SL, Jacques PF, Burke GL, Goodarzi M, Cheung CL, Wolf M, Rice K, Goltzman D, Hidiroglou N, Ladouceur M, Wareham NJ, Hocking LJ, Hart D, Arden NK, Cooper C, Malik S, Fraser WD, Hartikainen AL, Zhai G, Macdonald HM, Forouhi NG, Loos RJ, Reid DM, Hakim A, Dennison E, Liu Y, Power C, Stevens HE, Jaana L, Vasan RS, Soranzo N, Bojunga J, Psaty BM, Lorentzon M, Foroud T, Harris TB, Hofman A, Jansson JO, Cauley JA, Uitterlinden AG, Gibson Q, Järvelin MR, Karasik D, Siscovick DS, Econs MJ, Kritchevsky SB, Florez JC, Todd JA, Dupuis J, Hyppönen E, Spector TD. Common genetic determinants of vitamin D insufficiency: a genome-wide association study. Lancet. 2010 Jul 17; 376(9736):180-8.
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  371. Henrichs J, Bongers-Schokking JJ, Schenk JJ, Ghassabian A, Schmidt HG, Visser TJ, Hooijkaas H, de Muinck Keizer-Schrama SM, Hofman A, Jaddoe VV, Visser W, Steegers EA, Verhulst FC, de Rijke YB, Tiemeier H. Maternal thyroid function during early pregnancy and cognitive functioning in early childhood: the generation R study. J Clin Endocrinol Metab. 2010 Sep; 95(9):4227-34.
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  372. Ruiter R, Visser LE, Eijgelsheim M, Rodenburg EM, Hofman A, Coebergh JW, Nijsten T, Stricker BH. High-ceiling diuretics are associated with an increased risk of basal cell carcinoma in a population-based follow-up study. Eur J Cancer. 2010 Sep; 46(13):2467-72.
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  373. Luijendijk HJ, Tiemeier H, van den Berg JF, Bleumink GS, Hofman A, Stricker BH. Heart failure and incident late-life depression. J Am Geriatr Soc. 2010 Aug; 58(8):1441-8.
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  374. Newson RS, Witteman JC, Franco OH, Stricker BH, Breteler MM, Hofman A, Tiemeier H. Predicting survival and morbidity-free survival to very old age. Age (Dordr). 2010 Dec; 32(4):521-34.
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  375. Kerkhof HJ, Bierma-Zeinstra SM, Castano-Betancourt MC, de Maat MP, Hofman A, Pols HA, Rivadeneira F, Witteman JC, Uitterlinden AG, van Meurs JB. Serum C reactive protein levels and genetic variation in the CRP gene are not associated with the prevalence, incidence or progression of osteoarthritis independent of body mass index. Ann Rheum Dis. 2010 Nov; 69(11):1976-82.
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  376. Luijk MP, Velders FP, Tharner A, van Ijzendoorn MH, Bakermans-Kranenburg MJ, Jaddoe VW, Hofman A, Verhulst FC, Tiemeier H. FKBP5 and resistant attachment predict cortisol reactivity in infants: gene-environment interaction. Psychoneuroendocrinology. 2010 Nov; 35(10):1454-61.
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  377. Dierckx B, Tulen JH, Tharner A, Jaddoe VW, Hofman A, Verhulst FC, Tiemeier H. Low autonomic arousal as vulnerability to externalising behaviour in infants with hostile mothers. Psychiatry Res. 2011 Jan 30; 185(1-2):171-5.
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  378. Kardys I, Deckers JW, Stricker BH, Vletter WB, Hofman A, Witteman J. Distribution of echocardiographic parameters and their associations with cardiovascular risk factors in the Rotterdam Study. Eur J Epidemiol. 2010 Jul; 25(7):481-90.
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  379. Leening MJ, Elias-Smale SE, Felix JF, Kors JA, Deckers JW, Hofman A, Stricker BH, Witteman JC. Unrecognised myocardial infarction and long-term risk of heart failure in the elderly: the Rotterdam Study. Heart. 2010 Sep; 96(18):1458-62.
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  380. Silva LM, Jansen PW, Steegers EA, Jaddoe VW, Arends LR, Tiemeier H, Verhulst FC, Moll HA, Hofman A, Mackenbach JP, Raat H. Mother's educational level and fetal growth: the genesis of health inequalities. Int J Epidemiol. 2010 Oct; 39(5):1250-61.
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  381. Seshadri S, Fitzpatrick AL, Ikram MA, DeStefano AL, Gudnason V, Boada M, Bis JC, Smith AV, Carassquillo MM, Lambert JC, Harold D, Schrijvers EM, Ramirez-Lorca R, Debette S, Longstreth WT, Janssens AC, Pankratz VS, Dartigues JF, Hollingworth P, Aspelund T, Hernandez I, Beiser A, Kuller LH, Koudstaal PJ, Dickson DW, Tzourio C, Abraham R, Antunez C, Du Y, Rotter JI, Aulchenko YS, Harris TB, Petersen RC, Berr C, Owen MJ, Lopez-Arrieta J, Varadarajan BN, Becker JT, Rivadeneira F, Nalls MA, Graff-Radford NR, Campion D, Auerbach S, Rice K, Hofman A, Jonsson PV, Schmidt H, Lathrop M, Mosley TH, Au R, Psaty BM, Uitterlinden AG, Farrer LA, Lumley T, Ruiz A, Williams J, Amouyel P, Younkin SG, Wolf PA, Launer LJ, Lopez OL, van Duijn CM, Breteler MM. Genome-wide analysis of genetic loci associated with Alzheimer disease. JAMA. 2010 May 12; 303(18):1832-40.
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  382. Schol-Gelok S, Janssens AC, Tiemeier H, Liu F, Lopez-Leon S, Zorkoltseva IV, Axenovich TI, van Swieten JC, Uitterlinden AG, Hofman A, Aulchenko YS, Oostra BA, van Duijn CM. A genome-wide screen for depression in two independent Dutch populations. Biol Psychiatry. 2010 Jul 15; 68(2):187-96.
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  383. Liu F, Wollstein A, Hysi PG, Ankra-Badu GA, Spector TD, Park D, Zhu G, Larsson M, Duffy DL, Montgomery GW, Mackey DA, Walsh S, Lao O, Hofman A, Rivadeneira F, Vingerling JR, Uitterlinden AG, Martin NG, Hammond CJ, Kayser M. Digital quantification of human eye color highlights genetic association of three new loci. PLoS Genet. 2010 May; 6(5):e1000934.
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  384. El Marroun H, Tiemeier H, Steegers EA, Roos-Hesselink JW, Jaddoe VW, Hofman A, Verhulst FC, van den Brink W, Huizink AC. A prospective study on intrauterine cannabis exposure and fetal blood flow. Early Hum Dev. 2010 Apr; 86(4):231-6.
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  385. Smith NL, Felix JF, Morrison AC, Demissie S, Glazer NL, Loehr LR, Cupples LA, Dehghan A, Lumley T, Rosamond WD, Lieb W, Rivadeneira F, Bis JC, Folsom AR, Benjamin E, Aulchenko YS, Haritunians T, Couper D, Murabito J, Wang YA, Stricker BH, Gottdiener JS, Chang PP, Wang TJ, Rice KM, Hofman A, Heckbert SR, Fox ER, O'Donnell CJ, Uitterlinden AG, Rotter JI, Willerson JT, Levy D, van Duijn CM, Psaty BM, Witteman JC, Boerwinkle E, Vasan RS. Association of genome-wide variation with the risk of incident heart failure in adults of European and African ancestry: a prospective meta-analysis from the cohorts for heart and aging research in genomic epidemiology (CHARGE) consortium. Circ Cardiovasc Genet. 2010 Jun; 3(3):256-66.
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  386. Mohangoo AD, de Koning HJ, Hafkamp-de Groen E, van der Wouden JC, Jaddoe VW, Moll HA, Hofman A, Mackenbach JP, de Jongste JC, Raat H. A comparison of parent-reported wheezing or shortness of breath among infants as assessed by questionnaire and physician-interview: The Generation R study. Pediatr Pulmonol. 2010 May; 45(5):500-7.
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  387. Ikram MK, Luijendijk HJ, Hofman A, de Jong PT, Breteler MM, Vingerling JR, Tiemeier H. Retinal vascular calibers and risk of late-life depression: The Rotterdam Study. Am J Geriatr Psychiatry. 2010 May; 18(5):452-5.
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  388. Mattace-Raso FU, Verwoert GC, Hofman A, Witteman JC. Inflammation and incident-isolated systolic hypertension in older adults: the Rotterdam study. J Hypertens. 2010 May; 28(5):892-5.
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  389. Bakker R, Steegers EA, Obradov A, Raat H, Hofman A, Jaddoe VW. Maternal caffeine intake from coffee and tea, fetal growth, and the risks of adverse birth outcomes: the Generation R Study. Am J Clin Nutr. 2010 Jun; 91(6):1691-8.
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  390. Thorgeirsson TE, Gudbjartsson DF, Surakka I, Vink JM, Amin N, Geller F, Sulem P, Rafnar T, Esko T, Walter S, Gieger C, Rawal R, Mangino M, Prokopenko I, Mägi R, Keskitalo K, Gudjonsdottir IH, Gretarsdottir S, Stefansson H, Thompson JR, Aulchenko YS, Nelis M, Aben KK, den Heijer M, Dirksen A, Ashraf H, Soranzo N, Valdes AM, Steves C, Uitterlinden AG, Hofman A, Tönjes A, Kovacs P, Hottenga JJ, Willemsen G, Vogelzangs N, Döring A, Dahmen N, Nitz B, Pergadia ML, Saez B, De Diego V, Lezcano V, Garcia-Prats MD, Ripatti S, Perola M, Kettunen J, Hartikainen AL, Pouta A, Laitinen J, Isohanni M, Huei-Yi S, Allen M, Krestyaninova M, Hall AS, Jones GT, van Rij AM, Mueller T, Dieplinger B, Haltmayer M, Jonsson S, Matthiasson SE, Oskarsson H, Tyrfingsson T, Kiemeney LA, Mayordomo JI, Lindholt JS, Pedersen JH, Franklin WA, Wolf H, Montgomery GW, Heath AC, Martin NG, Madden PA, Giegling I, Rujescu D, Järvelin MR, Salomaa V, Stumvoll M, Spector TD, Wichmann HE, Metspalu A, Samani NJ, Penninx BW, Oostra BA, Boomsma DI, Tiemeier H, van Duijn CM, Kaprio J, Gulcher JR, McCarthy MI, Peltonen L, Thorsteinsdottir U, Stefansson K. Sequence variants at CHRNB3-CHRNA6 and CYP2A6 affect smoking behavior. Nat Genet. 2010 May; 42(5):448-53.
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  391. Morrison AC, Felix JF, Cupples LA, Glazer NL, Loehr LR, Dehghan A, Demissie S, Bis JC, Rosamond WD, Aulchenko YS, Wang YA, Haritunians T, Folsom AR, Rivadeneira F, Benjamin EJ, Lumley T, Couper D, Stricker BH, O'Donnell CJ, Rice KM, Chang PP, Hofman A, Levy D, Rotter JI, Fox ER, Uitterlinden AG, Wang TJ, Psaty BM, Willerson JT, van Duijn CM, Boerwinkle E, Witteman JC, Vasan RS, Smith NL. Genomic variation associated with mortality among adults of European and African ancestry with heart failure: the cohorts for heart and aging research in genomic epidemiology consortium. Circ Cardiovasc Genet. 2010 Jun; 3(3):248-55.
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  392. Euser SM, Sattar N, Witteman JC, Bollen EL, Sijbrands EJ, Hofman A, Perry IJ, Breteler MM, Westendorp RG. A prospective analysis of elevated fasting glucose levels and cognitive function in older people: results from PROSPER and the Rotterdam Study. Diabetes. 2010 Jul; 59(7):1601-7.
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  393. Bakker R, Pluimgraaff LE, Steegers EA, Raat H, Tiemeier H, Hofman A, Jaddoe VW. Associations of light and moderate maternal alcohol consumption with fetal growth characteristics in different periods of pregnancy: the Generation R Study. Int J Epidemiol. 2010 Jun; 39(3):777-89.
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  394. Köttgen A, Pattaro C, Böger CA, Fuchsberger C, Olden M, Glazer NL, Parsa A, Gao X, Yang Q, Smith AV, O'Connell JR, Li M, Schmidt H, Tanaka T, Isaacs A, Ketkar S, Hwang SJ, Johnson AD, Dehghan A, Teumer A, Paré G, Atkinson EJ, Zeller T, Lohman K, Cornelis MC, Probst-Hensch NM, Kronenberg F, Tönjes A, Hayward C, Aspelund T, Eiriksdottir G, Launer LJ, Harris TB, Rampersaud E, Mitchell BD, Arking DE, Boerwinkle E, Struchalin M, Cavalieri M, Singleton A, Giallauria F, Metter J, de Boer IH, Haritunians T, Lumley T, Siscovick D, Psaty BM, Zillikens MC, Oostra BA, Feitosa M, Province M, de Andrade M, Turner ST, Schillert A, Ziegler A, Wild PS, Schnabel RB, Wilde S, Munzel TF, Leak TS, Illig T, Klopp N, Meisinger C, Wichmann HE, Koenig W, Zgaga L, Zemunik T, Kolcic I, Minelli C, Hu FB, Johansson A, Igl W, Zaboli G, Wild SH, Wright AF, Campbell H, Ellinghaus D, Schreiber S, Aulchenko YS, Felix JF, Rivadeneira F, Uitterlinden AG, Hofman A, Imboden M, Nitsch D, Brandstätter A, Kollerits B, Kedenko L, Mägi R, Stumvoll M, Kovacs P, Boban M, Campbell S, Endlich K, Völzke H, Kroemer HK, Nauck M, Völker U, Polasek O, Vitart V, Badola S, Parker AN, Ridker PM, Kardia SL, Blankenberg S, Liu Y, Curhan GC, Franke A, Rochat T, Paulweber B, Prokopenko I, Wang W, Gudnason V, Shuldiner AR, Coresh J, Schmidt R, Ferrucci L, Shlipak MG, van Duijn CM, Borecki I, Krämer BK, Rudan I, Gyllensten U, Wilson JF, Witteman JC, Pramstaller PP, Rettig R, Hastie N, Chasman DI, Kao WH, Heid IM, Fox CS. New loci associated with kidney function and chronic kidney disease. Nat Genet. 2010 May; 42(5):376-84.
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  395. Freathy RM, Mook-Kanamori DO, Sovio U, Prokopenko I, Timpson NJ, Berry DJ, Warrington NM, Widen E, Hottenga JJ, Kaakinen M, Lange LA, Bradfield JP, Kerkhof M, Marsh JA, Mägi R, Chen CM, Lyon HN, Kirin M, Adair LS, Aulchenko YS, Bennett AJ, Borja JB, Bouatia-Naji N, Charoen P, Coin LJ, Cousminer DL, de Geus EJ, Deloukas P, Elliott P, Evans DM, Froguel P, Glaser B, Groves CJ, Hartikainen AL, Hassanali N, Hirschhorn JN, Hofman A, Holly JM, Hyppönen E, Kanoni S, Knight BA, Laitinen J, Lindgren CM, McArdle WL, O'Reilly PF, Pennell CE, Postma DS, Pouta A, Ramasamy A, Rayner NW, Ring SM, Rivadeneira F, Shields BM, Strachan DP, Surakka I, Taanila A, Tiesler C, Uitterlinden AG, van Duijn CM, Wijga AH, Willemsen G, Zhang H, Zhao J, Wilson JF, Steegers EA, Hattersley AT, Eriksson JG, Peltonen L, Mohlke KL, Grant SF, Hakonarson H, Koppelman GH, Dedoussis GV, Heinrich J, Gillman MW, Palmer LJ, Frayling TM, Boomsma DI, Davey Smith G, Power C, Jaddoe VW, Jarvelin MR, McCarthy MI. Variants in ADCY5 and near CCNL1 are associated with fetal growth and birth weight. Nat Genet. 2010 May; 42(5):430-5.
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  396. den Heijer T, van der Lijn F, Koudstaal PJ, Hofman A, van der Lugt A, Krestin GP, Niessen WJ, Breteler MM. A 10-year follow-up of hippocampal volume on magnetic resonance imaging in early dementia and cognitive decline. Brain. 2010 Apr; 133(Pt 4):1163-72.
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  397. Zillikens MC, van Meurs JB, Rivadeneira F, Hofman A, Oostra BA, Sijbrands EJ, Witteman JC, Pols HA, van Duijn CM, Uitterlinden AG. Interactions between dietary vitamin E intake and SIRT1 genetic variation influence body mass index. Am J Clin Nutr. 2010 May; 91(5):1387-93.
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  398. Newman AB, Walter S, Lunetta KL, Garcia ME, Slagboom PE, Christensen K, Arnold AM, Aspelund T, Aulchenko YS, Benjamin EJ, Christiansen L, D'Agostino RB, Fitzpatrick AL, Franceschini N, Glazer NL, Gudnason V, Hofman A, Kaplan R, Karasik D, Kelly-Hayes M, Kiel DP, Launer LJ, Marciante KD, Massaro JM, Miljkovic I, Nalls MA, Hernandez D, Psaty BM, Rivadeneira F, Rotter J, Seshadri S, Smith AV, Taylor KD, Tiemeier H, Uh HW, Uitterlinden AG, Vaupel JW, Walston J, Westendorp RG, Harris TB, Lumley T, van Duijn CM, Murabito JM. A meta-analysis of four genome-wide association studies of survival to age 90 years or older: the Cohorts for Heart and Aging Research in Genomic Epidemiology Consortium. J Gerontol A Biol Sci Med Sci. 2010 May; 65(5):478-87.
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  399. Smith NL, Chen MH, Dehghan A, Strachan DP, Basu S, Soranzo N, Hayward C, Rudan I, Sabater-Lleal M, Bis JC, de Maat MP, Rumley A, Kong X, Yang Q, Williams FM, Vitart V, Campbell H, Mälarstig A, Wiggins KL, Van Duijn CM, McArdle WL, Pankow JS, Johnson AD, Silveira A, McKnight B, Uitterlinden AG, Aleksic N, Meigs JB, Peters A, Koenig W, Cushman M, Kathiresan S, Rotter JI, Bovill EG, Hofman A, Boerwinkle E, Tofler GH, Peden JF, Psaty BM, Leebeek F, Folsom AR, Larson MG, Spector TD, Wright AF, Wilson JF, Hamsten A, Lumley T, Witteman JC, Tang W, O'Donnell CJ. Novel associations of multiple genetic loci with plasma levels of factor VII, factor VIII, and von Willebrand factor: The CHARGE (Cohorts for Heart and Aging Research in Genome Epidemiology) Consortium. Circulation. 2010 Mar 30; 121(12):1382-92.
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  400. Heine-Bröring RC, Brouwer IA, Proença RV, van Rooij FJ, Hofman A, Oudkerk M, Witteman JC, Geleijnse JM. Intake of fish and marine n-3 fatty acids in relation to coronary calcification: the Rotterdam Study. Am J Clin Nutr. 2010 May; 91(5):1317-23.
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  401. Geelhoed MJ, Steegers EA, Koper JW, van Rossum EF, Moll HA, Raat H, Tiemeier H, Hofman A, Jaddoe VW. Glucocorticoid receptor gene polymorphisms do not affect growth in fetal and early postnatal life. The Generation R Study. BMC Med Genet. 2010; 11:39.
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  402. Coolman M, de Groot CJ, Jaddoe VW, Hofman A, Raat H, Steegers EA. Medical record validation of maternally reported history of preeclampsia. J Clin Epidemiol. 2010 Aug; 63(8):932-7.
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  403. de Schepper EI, Damen J, van Meurs JB, Ginai AZ, Popham M, Hofman A, Koes BW, Bierma-Zeinstra SM. The association between lumbar disc degeneration and low back pain: the influence of age, gender, and individual radiographic features. Spine (Phila Pa 1976). 2010 Mar 1; 35(5):531-6.
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  404. Ellinor PT, Lunetta KL, Glazer NL, Pfeufer A, Alonso A, Chung MK, Sinner MF, de Bakker PI, Mueller M, Lubitz SA, Fox E, Darbar D, Smith NL, Smith JD, Schnabel RB, Soliman EZ, Rice KM, Van Wagoner DR, Beckmann BM, van Noord C, Wang K, Ehret GB, Rotter JI, Hazen SL, Steinbeck G, Smith AV, Launer LJ, Harris TB, Makino S, Nelis M, Milan DJ, Perz S, Esko T, Köttgen A, Moebus S, Newton-Cheh C, Li M, Möhlenkamp S, Wang TJ, Kao WH, Vasan RS, Nöthen MM, MacRae CA, Stricker BH, Hofman A, Uitterlinden AG, Levy D, Boerwinkle E, Metspalu A, Topol EJ, Chakravarti A, Gudnason V, Psaty BM, Roden DM, Meitinger T, Wichmann HE, Witteman JC, Barnard J, Arking DE, Benjamin EJ, Heckbert SR, Kääb S. Common variants in KCNN3 are associated with lone atrial fibrillation. Nat Genet. 2010 Mar; 42(3):240-4.
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  405. Barbalic M, Dupuis J, Dehghan A, Bis JC, Hoogeveen RC, Schnabel RB, Nambi V, Bretler M, Smith NL, Peters A, Lu C, Tracy RP, Aleksic N, Heeriga J, Keaney JF, Rice K, Lip GY, Vasan RS, Glazer NL, Larson MG, Uitterlinden AG, Yamamoto J, Durda P, Haritunians T, Psaty BM, Boerwinkle E, Hofman A, Koenig W, Jenny NS, Witteman JC, Ballantyne C, Benjamin EJ. Large-scale genomic studies reveal central role of ABO in sP-selectin and sICAM-1 levels. Hum Mol Genet. 2010 May 1; 19(9):1863-72.
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  406. Mook-Kanamori DO, Steegers EA, Eilers PH, Raat H, Hofman A, Jaddoe VW. Risk factors and outcomes associated with first-trimester fetal growth restriction. JAMA. 2010 Feb 10; 303(6):527-34.
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  407. Maas JA, Mook-Kanamori DO, Ay L, Steegers EA, van Duijn CM, Hofman A, Hokken-Koelega AC, Jaddoe VW. Insulin VNTR and IGF-1 promoter region polymorphisms are not associated with body composition in early childhood: the generation R study. Horm Res Paediatr. 2010; 73(2):120-7.
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  408. Kerkhof HJ, Lories RJ, Meulenbelt I, Jonsdottir I, Valdes AM, Arp P, Ingvarsson T, Jhamai M, Jonsson H, Stolk L, Thorleifsson G, Zhai G, Zhang F, Zhu Y, van der Breggen R, Carr A, Doherty M, Doherty S, Felson DT, Gonzalez A, Halldorsson BV, Hart DJ, Hauksson VB, Hofman A, Ioannidis JP, Kloppenburg M, Lane NE, Loughlin J, Luyten FP, Nevitt MC, Parimi N, Pols HA, Rivadeneira F, Slagboom EP, Styrkársdóttir U, Tsezou A, van de Putte T, Zmuda J, Spector TD, Stefansson K, Uitterlinden AG, van Meurs JB. A genome-wide association study identifies an osteoarthritis susceptibility locus on chromosome 7q22. Arthritis Rheum. 2010 Feb; 62(2):499-510.
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  409. van Batenburg-Eddes T, de Groot L, Steegers EA, Hofman A, Jaddoe VW, Verhulst FC, Tiemeier H. Fetal programming of infant neuromotor development: the generation R study. Pediatr Res. 2010 Feb; 67(2):132-7.
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  410. Rutten JH, Mattace-Raso FU, Steyerberg EW, Lindemans J, Hofman A, Wieberdink RG, Breteler MM, Witteman JC, van den Meiracker AH. Amino-terminal pro-B-type natriuretic peptide improves cardiovascular and cerebrovascular risk prediction in the population: the Rotterdam study. Hypertension. 2010 Mar; 55(3):785-91.
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  411. Dupuis J, Langenberg C, Prokopenko I, Saxena R, Soranzo N, Jackson AU, Wheeler E, Glazer NL, Bouatia-Naji N, Gloyn AL, Lindgren CM, Mägi R, Morris AP, Randall J, Johnson T, Elliott P, Rybin D, Thorleifsson G, Steinthorsdottir V, Henneman P, Grallert H, Dehghan A, Hottenga JJ, Franklin CS, Navarro P, Song K, Goel A, Perry JR, Egan JM, Lajunen T, Grarup N, Sparsø T, Doney A, Voight BF, Stringham HM, Li M, Kanoni S, Shrader P, Cavalcanti-Proença C, Kumari M, Qi L, Timpson NJ, Gieger C, Zabena C, Rocheleau G, Ingelsson E, An P, O'Connell J, Luan J, Elliott A, McCarroll SA, Payne F, Roccasecca RM, Pattou F, Sethupathy P, Ardlie K, Ariyurek Y, Balkau B, Barter P, Beilby JP, Ben-Shlomo Y, Benediktsson R, Bennett AJ, Bergmann S, Bochud M, Boerwinkle E, Bonnefond A, Bonnycastle LL, Borch-Johnsen K, Böttcher Y, Brunner E, Bumpstead SJ, Charpentier G, Chen YD, Chines P, Clarke R, Coin LJ, Cooper MN, Cornelis M, Crawford G, Crisponi L, Day IN, de Geus EJ, Delplanque J, Dina C, Erdos MR, Fedson AC, Fischer-Rosinsky A, Forouhi NG, Fox CS, Frants R, Franzosi MG, Galan P, Goodarzi MO, Graessler J, Groves CJ, Grundy S, Gwilliam R, Gyllensten U, Hadjadj S, Hallmans G, Hammond N, Han X, Hartikainen AL, Hassanali N, Hayward C, Heath SC, Hercberg S, Herder C, Hicks AA, Hillman DR, Hingorani AD, Hofman A, Hui J, Hung J, Isomaa B, Johnson PR, Jørgensen T, Jula A, Kaakinen M, Kaprio J, Kesaniemi YA, Kivimaki M, Knight B, Koskinen S, Kovacs P, Kyvik KO, Lathrop GM, Lawlor DA, Le Bacquer O, Lecoeur C, Li Y, Lyssenko V, Mahley R, Mangino M, Manning AK, Martínez-Larrad MT, McAteer JB, McCulloch LJ, McPherson R, Meisinger C, Melzer D, Meyre D, Mitchell BD, Morken MA, Mukherjee S, Naitza S, Narisu N, Neville MJ, Oostra BA, Orrù M, Pakyz R, Palmer CN, Paolisso G, Pattaro C, Pearson D, Peden JF, Pedersen NL, Perola M, Pfeiffer AF, Pichler I, Polasek O, Posthuma D, Potter SC, Pouta A, Province MA, Psaty BM, Rathmann W, Rayner NW, Rice K, Ripatti S, Rivadeneira F, Roden M, Rolandsson O, Sandbaek A, Sandhu M, Sanna S, Sayer AA, Scheet P, Scott LJ, Seedorf U, Sharp SJ, Shields B, Sigurethsson G, Sijbrands EJ, Silveira A, Simpson L, Singleton A, Smith NL, Sovio U, Swift A, Syddall H, Syvänen AC, Tanaka T, Thorand B, Tichet J, Tönjes A, Tuomi T, Uitterlinden AG, van Dijk KW, van Hoek M, Varma D, Visvikis-Siest S, Vitart V, Vogelzangs N, Waeber G, Wagner PJ, Walley A, Walters GB, Ward KL, Watkins H, Weedon MN, Wild SH, Willemsen G, Witteman JC, Yarnell JW, Zeggini E, Zelenika D, Zethelius B, Zhai G, Zhao JH, Zillikens MC, Borecki IB, Loos RJ, Meneton P, Magnusson PK, Nathan DM, Williams GH, Hattersley AT, Silander K, Salomaa V, Smith GD, Bornstein SR, Schwarz P, Spranger J, Karpe F, Shuldiner AR, Cooper C, Dedoussis GV, Serrano-Ríos M, Morris AD, Lind L, Palmer LJ, Hu FB, Franks PW, Ebrahim S, Marmot M, Kao WH, Pankow JS, Sampson MJ, Kuusisto J, Laakso M, Hansen T, Pedersen O, Pramstaller PP, Wichmann HE, Illig T, Rudan I, Wright AF, Stumvoll M, Campbell H, Wilson JF, Bergman RN, Buchanan TA, Collins FS, Mohlke KL, Tuomilehto J, Valle TT, Altshuler D, Rotter JI, Siscovick DS, Penninx BW, Boomsma DI, Deloukas P, Spector TD, Frayling TM, Ferrucci L, Kong A, Thorsteinsdottir U, Stefansson K, van Duijn CM, Aulchenko YS, Cao A, Scuteri A, Schlessinger D, Uda M, Ruokonen A, Jarvelin MR, Waterworth DM, Vollenweider P, Peltonen L, Mooser V, Abecasis GR, Wareham NJ, Sladek R, Froguel P, Watanabe RM, Meigs JB, Groop L, Boehnke M, McCarthy MI, Florez JC, Barroso I. New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk. Nat Genet. 2010 Feb; 42(2):105-16.
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  412. Pfeufer A, van Noord C, Marciante KD, Arking DE, Larson MG, Smith AV, Tarasov KV, Müller M, Sotoodehnia N, Sinner MF, Verwoert GC, Li M, Kao WH, Köttgen A, Coresh J, Bis JC, Psaty BM, Rice K, Rotter JI, Rivadeneira F, Hofman A, Kors JA, Stricker BH, Uitterlinden AG, van Duijn CM, Beckmann BM, Sauter W, Gieger C, Lubitz SA, Newton-Cheh C, Wang TJ, Magnani JW, Schnabel RB, Chung MK, Barnard J, Smith JD, Van Wagoner DR, Vasan RS, Aspelund T, Eiriksdottir G, Harris TB, Launer LJ, Najjar SS, Lakatta E, Schlessinger D, Uda M, Abecasis GR, Müller-Myhsok B, Ehret GB, Boerwinkle E, Chakravarti A, Soliman EZ, Lunetta KL, Perz S, Wichmann HE, Meitinger T, Levy D, Gudnason V, Ellinor PT, Sanna S, Kääb S, Witteman JC, Alonso A, Benjamin EJ, Heckbert SR. Genome-wide association study of PR interval. Nat Genet. 2010 Feb; 42(2):153-9.
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  413. Ikram MA, Luijendijk HJ, Vernooij MW, Hofman A, Niessen WJ, van der Lugt A, Tiemeier H, Breteler MM. Vascular brain disease and depression in the elderly. Epidemiology. 2010 Jan; 21(1):78-81.
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  414. Becker ML, Visser LE, van Schaik RH, Hofman A, Uitterlinden AG, Stricker BH. Influence of genetic variation in CYP3A4 and ABCB1 on dose decrease or switching during simvastatin and atorvastatin therapy. Pharmacoepidemiol Drug Saf. 2010 Jan; 19(1):75-81.
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  415. Becker ML, Visser LE, van Schaik RH, Hofman A, Uitterlinden AG, Stricker BH. Interaction between polymorphisms in the OCT1 and MATE1 transporter and metformin response. Pharmacogenet Genomics. 2010 Jan; 20(1):38-44.
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  416. Debette S, Bis JC, Fornage M, Schmidt H, Ikram MA, Sigurdsson S, Heiss G, Struchalin M, Smith AV, van der Lugt A, DeCarli C, Lumley T, Knopman DS, Enzinger C, Eiriksdottir G, Koudstaal PJ, DeStefano AL, Psaty BM, Dufouil C, Catellier DJ, Fazekas F, Aspelund T, Aulchenko YS, Beiser A, Rotter JI, Tzourio C, Shibata DK, Tscherner M, Harris TB, Rivadeneira F, Atwood LD, Rice K, Gottesman RF, van Buchem MA, Uitterlinden AG, Kelly-Hayes M, Cushman M, Zhu Y, Boerwinkle E, Gudnason V, Hofman A, Romero JR, Lopez O, van Duijn CM, Au R, Heckbert SR, Wolf PA, Mosley TH, Seshadri S, Breteler MM, Schmidt R, Launer LJ, Longstreth WT. Genome-wide association studies of MRI-defined brain infarcts: meta-analysis from the CHARGE Consortium. Stroke. 2010 Feb; 41(2):210-7.
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  417. van den Hooven EH, Jaddoe VW, de Kluizenaar Y, Hofman A, Mackenbach JP, Steegers EA, Miedema HM, Pierik FH. Residential traffic exposure and pregnancy-related outcomes: a prospective birth cohort study. Environ Health. 2009; 8:59.
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  418. Baas DC, Ho L, Ennis S, Merriam JE, Tanck MW, Uitterlinden AG, de Jong PT, Cree AJ, Griffiths HL, Rivadeneira F, Hofman A, van Duijn C, Smith RT, Barile GR, Gorgels TG, Vingerling JR, Klaver CC, Lotery AJ, Allikmets R, Bergen AA. The complement component 5 gene and age-related macular degeneration. Ophthalmology. 2010 Mar; 117(3):500-11.
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  419. Saridjan NS, Huizink AC, Koetsier JA, Jaddoe VW, Mackenbach JP, Hofman A, Kirschbaum C, Verhulst FC, Tiemeier H. Do social disadvantage and early family adversity affect the diurnal cortisol rhythm in infants? The Generation R Study. Horm Behav. 2010 Feb; 57(2):247-54.
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  420. Hancock DB, Eijgelsheim M, Wilk JB, Gharib SA, Loehr LR, Marciante KD, Franceschini N, van Durme YM, Chen TH, Barr RG, Schabath MB, Couper DJ, Brusselle GG, Psaty BM, van Duijn CM, Rotter JI, Uitterlinden AG, Hofman A, Punjabi NM, Rivadeneira F, Morrison AC, Enright PL, North KE, Heckbert SR, Lumley T, Stricker BH, O'Connor GT, London SJ. Meta-analyses of genome-wide association studies identify multiple loci associated with pulmonary function. Nat Genet. 2010 Jan; 42(1):45-52.
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  421. van Noord C, Dörr M, Sturkenboom MC, Straus SM, Reffelmann T, Felix SB, Hofman A, Kors JA, Haring R, de Jong FH, Nauck M, Uitterlinden AG, Wallaschofski H, Witteman JC, Völzke H, Stricker BH. The association of serum testosterone levels and ventricular repolarization. Eur J Epidemiol. 2010; 25(1):21-8.
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  422. Jansen PW, Tiemeier H, Verhulst FC, Burdorf A, Jaddoe VW, Hofman A, Moll HA, Verburg BO, Steegers EA, Mackenbach JP, Raat H. Employment status and the risk of pregnancy complications: the Generation R Study. Occup Environ Med. 2010 Jun; 67(6):387-94.
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  423. El Marroun H, Tiemeier H, Steegers EA, Jaddoe VW, Hofman A, Verhulst FC, van den Brink W, Huizink AC. Intrauterine cannabis exposure affects fetal growth trajectories: the Generation R Study. J Am Acad Child Adolesc Psychiatry. 2009 Dec; 48(12):1173-81.
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  424. Hek K, Mulder CL, Luijendijk HJ, van Duijn CM, Hofman A, Uitterlinden AG, Tiemeier H. The PCLO gene and depressive disorders: replication in a population-based study. Hum Mol Genet. 2010 Feb 15; 19(4):731-4.
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  425. Lebon A, Moll HA, Tavakol M, van Wamel WJ, Jaddoe VW, Hofman A, Verbrugh HA, van Belkum A. Correlation of bacterial colonization status between mother and child: the Generation R Study. J Clin Microbiol. 2010 Mar; 48(3):960-2.
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  426. Choté AA, de Groot CJ, Bruijnzeels MA, Redekop K, Jaddoe VW, Hofman A, Steegers EA, Mackenbach JP, Foets M. Ethnic differences in antenatal care use in a large multi-ethnic urban population in the Netherlands. Midwifery. 2011 Feb; 27(1):36-41.
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  427. Geelhoed JJ, Taal HR, Steegers EA, Arends LR, Lequin M, Moll HA, Hofman A, van der Heijden AJ, Jaddoe VW. Kidney growth curves in healthy children from the third trimester of pregnancy until the age of two years. The Generation R Study. Pediatr Nephrol. 2010 Feb; 25(2):289-98.
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  428. van Noord C, Sturkenboom MC, Straus SM, Hofman A, Kors JA, Witteman JC, Stricker BH. Serum glucose and insulin are associated with QTc and RR intervals in nondiabetic elderly. Eur J Endocrinol. 2010 Feb; 162(2):241-8.
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  429. Becker ML, Visser LE, van Schaik RH, Hofman A, Uitterlinden AG, Stricker BH. Common genetic variation in the ABCB1 gene is associated with the cholesterol-lowering effect of simvastatin in males. Pharmacogenomics. 2009 Nov; 10(11):1743-51.
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  430. Richards JB, Kavvoura FK, Rivadeneira F, Styrkársdóttir U, Estrada K, Halldórsson BV, Hsu YH, Zillikens MC, Wilson SG, Mullin BH, Amin N, Aulchenko YS, Cupples LA, Deloukas P, Demissie S, Hofman A, Kong A, Karasik D, van Meurs JB, Oostra BA, Pols HA, Sigurdsson G, Thorsteinsdottir U, Soranzo N, Williams FM, Zhou Y, Ralston SH, Thorleifsson G, van Duijn CM, Kiel DP, Stefansson K, Uitterlinden AG, Ioannidis JP, Spector TD. Collaborative meta-analysis: associations of 150 candidate genes with osteoporosis and osteoporotic fracture. Ann Intern Med. 2009 Oct 20; 151(8):528-37.
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  431. Henrichs J, Schenk JJ, Barendregt CS, Schmidt HG, Steegers EA, Hofman A, Jaddoe VW, Moll HA, Verhulst FC, Tiemeier H. Fetal growth from mid- to late pregnancy is associated with infant development: the Generation R Study. Dev Med Child Neurol. 2010 Jul; 52(7):644-51.
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  432. Ganesh SK, Zakai NA, van Rooij FJ, Soranzo N, Smith AV, Nalls MA, Chen MH, Kottgen A, Glazer NL, Dehghan A, Kuhnel B, Aspelund T, Yang Q, Tanaka T, Jaffe A, Bis JC, Verwoert GC, Teumer A, Fox CS, Guralnik JM, Ehret GB, Rice K, Felix JF, Rendon A, Eiriksdottir G, Levy D, Patel KV, Boerwinkle E, Rotter JI, Hofman A, Sambrook JG, Hernandez DG, Zheng G, Bandinelli S, Singleton AB, Coresh J, Lumley T, Uitterlinden AG, Vangils JM, Launer LJ, Cupples LA, Oostra BA, Zwaginga JJ, Ouwehand WH, Thein SL, Meisinger C, Deloukas P, Nauck M, Spector TD, Gieger C, Gudnason V, van Duijn CM, Psaty BM, Ferrucci L, Chakravarti A, Greinacher A, O'Donnell CJ, Witteman JC, Furth S, Cushman M, Harris TB, Lin JP. Multiple loci influence erythrocyte phenotypes in the CHARGE Consortium. Nat Genet. 2009 Nov; 41(11):1191-8.
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  433. Rivadeneira F, Styrkársdottir U, Estrada K, Halldórsson BV, Hsu YH, Richards JB, Zillikens MC, Kavvoura FK, Amin N, Aulchenko YS, Cupples LA, Deloukas P, Demissie S, Grundberg E, Hofman A, Kong A, Karasik D, van Meurs JB, Oostra B, Pastinen T, Pols HA, Sigurdsson G, Soranzo N, Thorleifsson G, Thorsteinsdottir U, Williams FM, Wilson SG, Zhou Y, Ralston SH, van Duijn CM, Spector T, Kiel DP, Stefansson K, Ioannidis JP, Uitterlinden AG. Twenty bone-mineral-density loci identified by large-scale meta-analysis of genome-wide association studies. Nat Genet. 2009 Nov; 41(11):1199-206.
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  434. van den Berg JF, Miedema HM, Tulen JH, Hofman A, Neven AK, Tiemeier H. Sex differences in subjective and actigraphic sleep measures: a population-based study of elderly persons. Sleep. 2009 Oct; 32(10):1367-75.
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  435. Dijkstra SC, Brouwer IA, van Rooij FJ, Hofman A, Witteman JC, Geleijnse JM. Intake of very long chain n-3 fatty acids from fish and the incidence of heart failure: the Rotterdam Study. Eur J Heart Fail. 2009 Oct; 11(10):922-8.
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  436. Roza SJ, van Batenburg-Eddes T, Steegers EA, Jaddoe VW, Mackenbach JP, Hofman A, Verhulst FC, Tiemeier H. Maternal folic acid supplement use in early pregnancy and child behavioural problems: The Generation R Study. Br J Nutr. 2010 Feb; 103(3):445-52.
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  437. Durmus B, Mook-Kanamori DO, Holzhauer S, Hofman A, van der Beek EM, Boehm G, Steegers EA, Jaddoe VW. Growth in foetal life and infancy is associated with abdominal adiposity at the age of 2 years: the generation R study. Clin Endocrinol (Oxf). 2010 May; 72(5):633-40.
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  438. Zillikens MC, van Meurs JB, Rivadeneira F, Amin N, Hofman A, Oostra BA, Sijbrands EJ, Witteman JC, Pols HA, van Duijn CM, Uitterlinden AG. SIRT1 genetic variation is related to BMI and risk of obesity. Diabetes. 2009 Dec; 58(12):2828-34.
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  439. Wolff N, Darlington AS, Hunfeld J, Verhulst F, Jaddoe V, Hofman A, Passchier J, Tiemeier H. Determinants of somatic complaints in 18-month-old children: the generation R study. J Pediatr Psychol. 2010 Apr; 35(3):306-16.
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  440. van Es MA, Veldink JH, Saris CG, Blauw HM, van Vught PW, Birve A, Lemmens R, Schelhaas HJ, Groen EJ, Huisman MH, van der Kooi AJ, de Visser M, Dahlberg C, Estrada K, Rivadeneira F, Hofman A, Zwarts MJ, van Doormaal PT, Rujescu D, Strengman E, Giegling I, Muglia P, Tomik B, Slowik A, Uitterlinden AG, Hendrich C, Waibel S, Meyer T, Ludolph AC, Glass JD, Purcell S, Cichon S, Nöthen MM, Wichmann HE, Schreiber S, Vermeulen SH, Kiemeney LA, Wokke JH, Cronin S, McLaughlin RL, Hardiman O, Fumoto K, Pasterkamp RJ, Meininger V, Melki J, Leigh PN, Shaw CE, Landers JE, Al-Chalabi A, Brown RH, Robberecht W, Andersen PM, Ophoff RA, van den Berg LH. Genome-wide association study identifies 19p13.3 (UNC13A) and 9p21.2 as susceptibility loci for sporadic amyotrophic lateral sclerosis. Nat Genet. 2009 Oct; 41(10):1083-7.
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  441. van Noord C, Sturkenboom MC, Straus SM, Hofman A, Witteman JC, Stricker BH. Population-based studies of antithyroid drugs and sudden cardiac death. Br J Clin Pharmacol. 2009 Sep; 68(3):447-54.
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  442. Wolff NJ, Darlington AS, Hunfeld JA, Verhulst FC, Jaddoe VW, Moll HA, Hofman A, Passchier J, Tiemeier H. The association of parent behaviors, chronic pain, and psychological problems with venipuncture distress in infants: the Generation R study. Health Psychol. 2009 Sep; 28(5):605-13.
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  443. van Woudenbergh GJ, van Ballegooijen AJ, Kuijsten A, Sijbrands EJ, van Rooij FJ, Geleijnse JM, Hofman A, Witteman JC, Feskens EJ. Eating fish and risk of type 2 diabetes: A population-based, prospective follow-up study. Diabetes Care. 2009 Nov; 32(11):2021-6.
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  444. Grundberg E, Kwan T, Ge B, Lam KC, Koka V, Kindmark A, Mallmin H, Dias J, Verlaan DJ, Ouimet M, Sinnett D, Rivadeneira F, Estrada K, Hofman A, van Meurs JM, Uitterlinden A, Beaulieu P, Graziani A, Harmsen E, Ljunggren O, Ohlsson C, Mellström D, Karlsson MK, Nilsson O, Pastinen T. Population genomics in a disease targeted primary cell model. Genome Res. 2009 Nov; 19(11):1942-52.
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  445. Mihaescu R, van Hoek M, Sijbrands EJ, Uitterlinden AG, Witteman JC, Hofman A, van Duijn CM, Janssens AC. Evaluation of risk prediction updates from commercial genome-wide scans. Genet Med. 2009 Aug; 11(8):588-94.
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  446. Kwadijk-de Gijsel S, Bijl MJ, Visser LE, van Schaik RH, Hofman A, Vulto AG, van Gelder T, Ch Stricker BH. Variation in the CYP2D6 gene is associated with a lower serum sodium concentration in patients on antidepressants. Br J Clin Pharmacol. 2009 Aug; 68(2):221-5.
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  447. Bergink AP, Uitterlinden AG, Van Leeuwen JP, Buurman CJ, Hofman A, Verhaar JA, Pols HA. Vitamin D status, bone mineral density, and the development of radiographic osteoarthritis of the knee: The Rotterdam Study. J Clin Rheumatol. 2009 Aug; 15(5):230-7.
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  448. Lebon A, Labout JA, Verbrugh HA, Jaddoe VW, Hofman A, van Wamel WJ, van Belkum A, Moll HA. Role of Staphylococcus aureus nasal colonization in atopic dermatitis in infants: the Generation R Study. Arch Pediatr Adolesc Med. 2009 Aug; 163(8):745-9.
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  449. Eijgelsheim M, Newton-Cheh C, Aarnoudse AL, van Noord C, Witteman JC, Hofman A, Uitterlinden AG, Stricker BH. Genetic variation in NOS1AP is associated with sudden cardiac death: evidence from the Rotterdam Study. Hum Mol Genet. 2009 Nov 1; 18(21):4213-8.
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  450. Holzhauer S, Zwijsen RM, Jaddoe VW, Boehm G, Moll HA, Mulder PG, Kleyburg-Linkers VA, Hofman A, Witteman JC. Sonographic assessment of abdominal fat distribution in infancy. Eur J Epidemiol. 2009; 24(9):521-9.
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  451. Mook-Kanamori DO, de Kort SW, van Duijn CM, Uitterlinden AG, Hofman A, Moll HA, Steegers EA, Hokken-Koelega AC, Jaddoe VW. Type 2 diabetes gene TCF7L2 polymorphism is not associated with fetal and postnatal growth in two birth cohort studies. BMC Med Genet. 2009; 10:67.
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  452. van den Berg JF, Luijendijk HJ, Tulen JH, Hofman A, Neven AK, Tiemeier H. Sleep in depression and anxiety disorders: a population-based study of elderly persons. J Clin Psychiatry. 2009 Aug; 70(8):1105-13.
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  453. Benjamin EJ, Rice KM, Arking DE, Pfeufer A, van Noord C, Smith AV, Schnabel RB, Bis JC, Boerwinkle E, Sinner MF, Dehghan A, Lubitz SA, D'Agostino RB, Lumley T, Ehret GB, Heeringa J, Aspelund T, Newton-Cheh C, Larson MG, Marciante KD, Soliman EZ, Rivadeneira F, Wang TJ, Eiríksdottir G, Levy D, Psaty BM, Li M, Chamberlain AM, Hofman A, Vasan RS, Harris TB, Rotter JI, Kao WH, Agarwal SK, Stricker BH, Wang K, Launer LJ, Smith NL, Chakravarti A, Uitterlinden AG, Wolf PA, Sotoodehnia N, Köttgen A, van Duijn CM, Meitinger T, Mueller M, Perz S, Steinbeck G, Wichmann HE, Lunetta KL, Heckbert SR, Gudnason V, Alonso A, Kääb S, Ellinor PT, Witteman JC. Variants in ZFHX3 are associated with atrial fibrillation in individuals of European ancestry. Nat Genet. 2009 Aug; 41(8):879-81.
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  454. Vasan RS, Glazer NL, Felix JF, Lieb W, Wild PS, Felix SB, Watzinger N, Larson MG, Smith NL, Dehghan A, Grosshennig A, Schillert A, Teumer A, Schmidt R, Kathiresan S, Lumley T, Aulchenko YS, König IR, Zeller T, Homuth G, Struchalin M, Aragam J, Bis JC, Rivadeneira F, Erdmann J, Schnabel RB, Dörr M, Zweiker R, Lind L, Rodeheffer RJ, Greiser KH, Levy D, Haritunians T, Deckers JW, Stritzke J, Lackner KJ, Völker U, Ingelsson E, Kullo I, Haerting J, O'Donnell CJ, Heckbert SR, Stricker BH, Ziegler A, Reffelmann T, Redfield MM, Werdan K, Mitchell GF, Rice K, Arnett DK, Hofman A, Gottdiener JS, Uitterlinden AG, Meitinger T, Blettner M, Friedrich N, Wang TJ, Psaty BM, van Duijn CM, Wichmann HE, Munzel TF, Kroemer HK, Benjamin EJ, Rotter JI, Witteman JC, Schunkert H, Schmidt H, Völzke H, Blankenberg S. Genetic variants associated with cardiac structure and function: a meta-analysis and replication of genome-wide association data. JAMA. 2009 Jul 8; 302(2):168-78.
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  455. Teichert M, Eijgelsheim M, Rivadeneira F, Uitterlinden AG, van Schaik RH, Hofman A, De Smet PA, van Gelder T, Visser LE, Stricker BH. A genome-wide association study of acenocoumarol maintenance dosage. Hum Mol Genet. 2009 Oct 1; 18(19):3758-68.
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  456. Sie MP, Isaacs A, de Maat MP, Mattace-Raso FU, Uitterlinden AG, Kardys I, Hofman A, Hoeks AP, Reneman RS, van Duijn CM, Witteman JC. Genetic variation in the fibrinogen-alpha and fibrinogen-gamma genes in relation to arterial stiffness: the Rotterdam Study. J Hypertens. 2009 Jul; 27(7):1392-8.
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  457. van den Berg MP, van der Ende J, Crijnen AA, Jaddoe VW, Moll HA, Mackenbach JP, Hofman A, Hengeveld MW, Tiemeier H, Verhulst FC. Paternal depressive symptoms during pregnancy are related to excessive infant crying. Pediatrics. 2009 Jul; 124(1):e96-103.
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  458. Sie MP, Yazdanpanah M, Mattace-Raso FU, Uitterlinden AG, Hofman A, Hoeks AP, Reneman RS, Asmar R, Van Duijn CM, Witteman JC. Genetic variation in the renin-angiotensin system and arterial stiffness. The Rotterdam Study. Clin Exp Hypertens. 2009 Jul; 31(5):389-99.
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  459. Geelhoed JJ, Steegers EA, van Osch-Gevers L, Verburg BO, Hofman A, Witteman JC, van der Heijden AJ, Helbing WA, Jaddoe VW. Cardiac structures track during the first 2 years of life and are associated with fetal growth and hemodynamics: the Generation R Study. Am Heart J. 2009 Jul; 158(1):71-7.
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  460. Valdes AM, Lories RJ, van Meurs JB, Kerkhof H, Doherty S, Hofman A, Hart DJ, Zhang F, Luyten FP, Uitterlinden AG, Doherty M, Spector TD. Variation at the ANP32A gene is associated with risk of hip osteoarthritis in women. Arthritis Rheum. 2009 Jul; 60(7):2046-54.
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  461. Estrada K, Krawczak M, Schreiber S, van Duijn K, Stolk L, van Meurs JB, Liu F, Penninx BW, Smit JH, Vogelzangs N, Hottenga JJ, Willemsen G, de Geus EJ, Lorentzon M, von Eller-Eberstein H, Lips P, Schoor N, Pop V, de Keijzer J, Hofman A, Aulchenko YS, Oostra BA, Ohlsson C, Boomsma DI, Uitterlinden AG, van Duijn CM, Rivadeneira F, Kayser M. A genome-wide association study of northwestern Europeans involves the C-type natriuretic peptide signaling pathway in the etiology of human height variation. Hum Mol Genet. 2009 Sep 15; 18(18):3516-24.
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  462. Heard-Costa NL, Zillikens MC, Monda KL, Johansson A, Harris TB, Fu M, Haritunians T, Feitosa MF, Aspelund T, Eiriksdottir G, Garcia M, Launer LJ, Smith AV, Mitchell BD, McArdle PF, Shuldiner AR, Bielinski SJ, Boerwinkle E, Brancati F, Demerath EW, Pankow JS, Arnold AM, Chen YD, Glazer NL, McKnight B, Psaty BM, Rotter JI, Amin N, Campbell H, Gyllensten U, Pattaro C, Pramstaller PP, Rudan I, Struchalin M, Vitart V, Gao X, Kraja A, Province MA, Zhang Q, Atwood LD, Dupuis J, Hirschhorn JN, Jaquish CE, O'Donnell CJ, Vasan RS, White CC, Aulchenko YS, Estrada K, Hofman A, Rivadeneira F, Uitterlinden AG, Witteman JC, Oostra BA, Kaplan RC, Gudnason V, O'Connell JR, Borecki IB, van Duijn CM, Cupples LA, Fox CS, North KE. NRXN3 is a novel locus for waist circumference: a genome-wide association study from the CHARGE Consortium. PLoS Genet. 2009 Jun; 5(6):e1000539.
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  463. Lindgren CM, Heid IM, Randall JC, Lamina C, Steinthorsdottir V, Qi L, Speliotes EK, Thorleifsson G, Willer CJ, Herrera BM, Jackson AU, Lim N, Scheet P, Soranzo N, Amin N, Aulchenko YS, Chambers JC, Drong A, Luan J, Lyon HN, Rivadeneira F, Sanna S, Timpson NJ, Zillikens MC, Zhao JH, Almgren P, Bandinelli S, Bennett AJ, Bergman RN, Bonnycastle LL, Bumpstead SJ, Chanock SJ, Cherkas L, Chines P, Coin L, Cooper C, Crawford G, Doering A, Dominiczak A, Doney AS, Ebrahim S, Elliott P, Erdos MR, Estrada K, Ferrucci L, Fischer G, Forouhi NG, Gieger C, Grallert H, Groves CJ, Grundy S, Guiducci C, Hadley D, Hamsten A, Havulinna AS, Hofman A, Holle R, Holloway JW, Illig T, Isomaa B, Jacobs LC, Jameson K, Jousilahti P, Karpe F, Kuusisto J, Laitinen J, Lathrop GM, Lawlor DA, Mangino M, McArdle WL, Meitinger T, Morken MA, Morris AP, Munroe P, Narisu N, Nordström A, Nordström P, Oostra BA, Palmer CN, Payne F, Peden JF, Prokopenko I, Renström F, Ruokonen A, Salomaa V, Sandhu MS, Scott LJ, Scuteri A, Silander K, Song K, Yuan X, Stringham HM, Swift AJ, Tuomi T, Uda M, Vollenweider P, Waeber G, Wallace C, Walters GB, Weedon MN, Witteman JC, Zhang C, Zhang W, Caulfield MJ, Collins FS, Davey Smith G, Day IN, Franks PW, Hattersley AT, Hu FB, Jarvelin MR, Kong A, Kooner JS, Laakso M, Lakatta E, Mooser V, Morris AD, Peltonen L, Samani NJ, Spector TD, Strachan DP, Tanaka T, Tuomilehto J, Uitterlinden AG, van Duijn CM, Wareham NJ, Waterworth DM, Boehnke M, Deloukas P, Groop L, Hunter DJ, Thorsteinsdottir U, Schlessinger D, Wichmann HE, Frayling TM, Abecasis GR, Hirschhorn JN, Loos RJ, Stefansson K, Mohlke KL, Barroso I, McCarthy MI. Genome-wide association scan meta-analysis identifies three Loci influencing adiposity and fat distribution. PLoS Genet. 2009 Jun; 5(6):e1000508.
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  464. Fang Y, van Meurs JB, Arp P, van Leeuwen JP, Hofman A, Pols HA, Uitterlinden AG. Vitamin D binding protein genotype and osteoporosis. Calcif Tissue Int. 2009 Aug; 85(2):85-93.
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  465. van Rossem L, Oenema A, Steegers EA, Moll HA, Jaddoe VW, Hofman A, Mackenbach JP, Raat H. Are starting and continuing breastfeeding related to educational background? The generation R study. Pediatrics. 2009 Jun; 123(6):e1017-27.
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  466. Evangelou E, Chapman K, Meulenbelt I, Karassa FB, Loughlin J, Carr A, Doherty M, Doherty S, Gómez-Reino JJ, Gonzalez A, Halldorsson BV, Hauksson VB, Hofman A, Hart DJ, Ikegawa S, Ingvarsson T, Jiang Q, Jonsdottir I, Jonsson H, Kerkhof HJ, Kloppenburg M, Lane NE, Li J, Lories RJ, van Meurs JB, Näkki A, Nevitt MC, Rodriguez-Lopez J, Shi D, Slagboom PE, Stefansson K, Tsezou A, Wallis GA, Watson CM, Spector TD, Uitterlinden AG, Valdes AM, Ioannidis JP. Large-scale analysis of association between GDF5 and FRZB variants and osteoarthritis of the hip, knee, and hand. Arthritis Rheum. 2009 Jun; 60(6):1710-21.
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  467. van Houten VA, Steegers EA, Witteman JC, Moll HA, Hofman A, Jaddoe VW. Fetal and postnatal growth and blood pressure at the age of 2 years. The Generation R Study. J Hypertens. 2009 Jun; 27(6):1152-7.
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  468. Devore EE, Grodstein F, van Rooij FJ, Hofman A, Rosner B, Stampfer MJ, Witteman JC, Breteler MM. Dietary intake of fish and omega-3 fatty acids in relation to long-term dementia risk. Am J Clin Nutr. 2009 Jul; 90(1):170-6.
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  469. Stolk L, Zhai G, van Meurs JB, Verbiest MM, Visser JA, Estrada K, Rivadeneira F, Williams FM, Cherkas L, Deloukas P, Soranzo N, de Keyzer JJ, Pop VJ, Lips P, Lebrun CE, van der Schouw YT, Grobbee DE, Witteman J, Hofman A, Pols HA, Laven JS, Spector TD, Uitterlinden AG. Loci at chromosomes 13, 19 and 20 influence age at natural menopause. Nat Genet. 2009 Jun; 41(6):645-7.
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  470. Perry JR, Stolk L, Franceschini N, Lunetta KL, Zhai G, McArdle PF, Smith AV, Aspelund T, Bandinelli S, Boerwinkle E, Cherkas L, Eiriksdottir G, Estrada K, Ferrucci L, Folsom AR, Garcia M, Gudnason V, Hofman A, Karasik D, Kiel DP, Launer LJ, van Meurs J, Nalls MA, Rivadeneira F, Shuldiner AR, Singleton A, Soranzo N, Tanaka T, Visser JA, Weedon MN, Wilson SG, Zhuang V, Streeten EA, Harris TB, Murray A, Spector TD, Demerath EW, Uitterlinden AG, Murabito JM. Meta-analysis of genome-wide association data identifies two loci influencing age at menarche. Nat Genet. 2009 Jun; 41(6):648-50.
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  471. Levy D, Ehret GB, Rice K, Verwoert GC, Launer LJ, Dehghan A, Glazer NL, Morrison AC, Johnson AD, Aspelund T, Aulchenko Y, Lumley T, Köttgen A, Vasan RS, Rivadeneira F, Eiriksdottir G, Guo X, Arking DE, Mitchell GF, Mattace-Raso FU, Smith AV, Taylor K, Scharpf RB, Hwang SJ, Sijbrands EJ, Bis J, Harris TB, Ganesh SK, O'Donnell CJ, Hofman A, Rotter JI, Coresh J, Benjamin EJ, Uitterlinden AG, Heiss G, Fox CS, Witteman JC, Boerwinkle E, Wang TJ, Gudnason V, Larson MG, Chakravarti A, Psaty BM, van Duijn CM. Genome-wide association study of blood pressure and hypertension. Nat Genet. 2009 Jun; 41(6):677-87.
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  472. Köttgen A, Glazer NL, Dehghan A, Hwang SJ, Katz R, Li M, Yang Q, Gudnason V, Launer LJ, Harris TB, Smith AV, Arking DE, Astor BC, Boerwinkle E, Ehret GB, Ruczinski I, Scharpf RB, Chen YD, de Boer IH, Haritunians T, Lumley T, Sarnak M, Siscovick D, Benjamin EJ, Levy D, Upadhyay A, Aulchenko YS, Hofman A, Rivadeneira F, Uitterlinden AG, van Duijn CM, Chasman DI, Paré G, Ridker PM, Kao WH, Witteman JC, Coresh J, Shlipak MG, Fox CS. Multiple loci associated with indices of renal function and chronic kidney disease. Nat Genet. 2009 Jun; 41(6):712-7.
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  473. Johnson AD, Kavousi M, Smith AV, Chen MH, Dehghan A, Aspelund T, Lin JP, van Duijn CM, Harris TB, Cupples LA, Uitterlinden AG, Launer L, Hofman A, Rivadeneira F, Stricker B, Yang Q, O'Donnell CJ, Gudnason V, Witteman JC. Genome-wide association meta-analysis for total serum bilirubin levels. Hum Mol Genet. 2009 Jul 15; 18(14):2700-10.
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  474. Vernooij MW, Ikram MA, Vrooman HA, Wielopolski PA, Krestin GP, Hofman A, Niessen WJ, Van der Lugt A, Breteler MM. White matter microstructural integrity and cognitive function in a general elderly population. Arch Gen Psychiatry. 2009 May; 66(5):545-53.
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  475. Siiskonen SJ, Visser LE, Tiemeier H, Hofman A, Lamberts SW, Uitterlinden AG, Stricker BH. BclI glucocorticoid receptor polymorphism and smoking in the general population. Addict Biol. 2009 Jul; 14(3):349-55.
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  476. Euser SM, van Bemmel T, Schram MT, Gussekloo J, Hofman A, Westendorp RG, Breteler MM. The effect of age on the association between blood pressure and cognitive function later in life. J Am Geriatr Soc. 2009 Jul; 57(7):1232-7.
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  477. Engberink MF, Hendriksen MA, Schouten EG, van Rooij FJ, Hofman A, Witteman JC, Geleijnse JM. Inverse association between dairy intake and hypertension: the Rotterdam Study. Am J Clin Nutr. 2009 Jun; 89(6):1877-83.
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  478. Ikram MA, Seshadri S, Bis JC, Fornage M, DeStefano AL, Aulchenko YS, Debette S, Lumley T, Folsom AR, van den Herik EG, Bos MJ, Beiser A, Cushman M, Launer LJ, Shahar E, Struchalin M, Du Y, Glazer NL, Rosamond WD, Rivadeneira F, Kelly-Hayes M, Lopez OL, Coresh J, Hofman A, DeCarli C, Heckbert SR, Koudstaal PJ, Yang Q, Smith NL, Kase CS, Rice K, Haritunians T, Roks G, de Kort PL, Taylor KD, de Lau LM, Oostra BA, Uitterlinden AG, Rotter JI, Boerwinkle E, Psaty BM, Mosley TH, van Duijn CM, Breteler MM, Longstreth WT, Wolf PA. Genomewide association studies of stroke. N Engl J Med. 2009 Apr 23; 360(17):1718-28.
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  479. Vernooij MW, Haag MD, van der Lugt A, Hofman A, Krestin GP, Stricker BH, Breteler MM. Use of antithrombotic drugs and the presence of cerebral microbleeds: the Rotterdam Scan Study. Arch Neurol. 2009 Jun; 66(6):714-20.
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  480. Soranzo N, Rivadeneira F, Chinappen-Horsley U, Malkina I, Richards JB, Hammond N, Stolk L, Nica A, Inouye M, Hofman A, Stephens J, Wheeler E, Arp P, Gwilliam R, Jhamai PM, Potter S, Chaney A, Ghori MJ, Ravindrarajah R, Ermakov S, Estrada K, Pols HA, Williams FM, McArdle WL, van Meurs JB, Loos RJ, Dermitzakis ET, Ahmadi KR, Hart DJ, Ouwehand WH, Wareham NJ, Barroso I, Sandhu MS, Strachan DP, Livshits G, Spector TD, Uitterlinden AG, Deloukas P. Meta-analysis of genome-wide scans for human adult stature identifies novel Loci and associations with measures of skeletal frame size. PLoS Genet. 2009 Apr; 5(4):e1000445.
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  481. Dehghan A, Yang Q, Peters A, Basu S, Bis JC, Rudnicka AR, Kavousi M, Chen MH, Baumert J, Lowe GD, McKnight B, Tang W, de Maat M, Larson MG, Eyhermendy S, McArdle WL, Lumley T, Pankow JS, Hofman A, Massaro JM, Rivadeneira F, Kolz M, Taylor KD, van Duijn CM, Kathiresan S, Illig T, Aulchenko YS, Volcik KA, Johnson AD, Uitterlinden AG, Tofler GH, Gieger C, Psaty BM, Couper DJ, Boerwinkle E, Koenig W, O'Donnell CJ, Witteman JC, Strachan DP, Smith NL, Folsom AR. Association of novel genetic Loci with circulating fibrinogen levels: a genome-wide association study in 6 population-based cohorts. Circ Cardiovasc Genet. 2009 Apr; 2(2):125-33.
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  482. van Noord C, Aarnoudse AJ, Eijgelsheim M, Sturkenboom MC, Straus SM, Hofman A, Kors JA, Newton-Cheh C, Witteman JC, Stricker BH. Calcium channel blockers, NOS1AP, and heart-rate-corrected QT prolongation. Pharmacogenet Genomics. 2009 Apr; 19(4):260-6.
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  483. Bijl MJ, Luijendijk HJ, van den Berg JF, Visser LE, van Schaik RH, Hofman A, Vulto AG, van Gelder T, Tiemeier H, Stricker BH. Association between the CYP2D6*4 polymorphism and depression or anxiety in the elderly. Pharmacogenomics. 2009 Apr; 10(4):541-7.
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  484. Timmermans S, Jaddoe VW, Hofman A, Steegers-Theunissen RP, Steegers EA. Periconception folic acid supplementation, fetal growth and the risks of low birth weight and preterm birth: the Generation R Study. Br J Nutr. 2009 Sep; 102(5):777-85.
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  485. Newton-Cheh C, Eijgelsheim M, Rice KM, de Bakker PI, Yin X, Estrada K, Bis JC, Marciante K, Rivadeneira F, Noseworthy PA, Sotoodehnia N, Smith NL, Rotter JI, Kors JA, Witteman JC, Hofman A, Heckbert SR, O'Donnell CJ, Uitterlinden AG, Psaty BM, Lumley T, Larson MG, Stricker BH. Common variants at ten loci influence QT interval duration in the QTGEN Study. Nat Genet. 2009 Apr; 41(4):399-406.
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  486. Ay L, Van Houten VA, Steegers EA, Hofman A, Witteman JC, Jaddoe VW, Hokken-Koelega AC. Fetal and postnatal growth and body composition at 6 months of age. J Clin Endocrinol Metab. 2009 Jun; 94(6):2023-30.
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  487. Jansen PW, Tiemeier H, Looman CW, Jaddoe VW, Hofman A, Moll HA, Steegers EA, Verhulst FC, Mackenbach JP, Raat H. Explaining educational inequalities in birthweight: the Generation R Study. Paediatr Perinat Epidemiol. 2009 May; 23(3):216-28.
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  488. Liu F, van Duijn K, Vingerling JR, Hofman A, Uitterlinden AG, Janssens AC, Kayser M. Eye color and the prediction of complex phenotypes from genotypes. Curr Biol. 2009 Mar 10; 19(5):R192-3.
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  489. Vink JM, Smit AB, de Geus EJ, Sullivan P, Willemsen G, Hottenga JJ, Smit JH, Hoogendijk WJ, Zitman FG, Peltonen L, Kaprio J, Pedersen NL, Magnusson PK, Spector TD, Kyvik KO, Morley KI, Heath AC, Martin NG, Westendorp RG, Slagboom PE, Tiemeier H, Hofman A, Uitterlinden AG, Aulchenko YS, Amin N, van Duijn C, Penninx BW, Boomsma DI. Genome-wide association study of smoking initiation and current smoking. Am J Hum Genet. 2009 Mar; 84(3):367-79.
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  490. Kardys I, van Tiel CM, de Vries CJ, Pannekoek H, Uitterlinden AG, Hofman A, Witteman JC, de Maat MP. Haplotypes of the NR4A2/NURR1 gene and cardiovascular disease: the Rotterdam Study. Hum Mutat. 2009 Mar; 30(3):417-23.
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  491. Ho L, Witteman JC, Rohrer B, Hofman A, de Jong PT, Vingerling JR. Lipoprotein-associated phospholipase A2 and risk of age-related macular degeneration: the Rotterdam Study. Arch Ophthalmol. 2009 Mar; 127(3):340-1.
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  492. Henrichs J, Schenk JJ, Schmidt HG, Arends LR, Steegers EA, Hofman A, Jaddoe VW, Verhulst FC, Tiemeier H. Fetal size in mid- and late pregnancy is related to infant alertness: the generation R study. Dev Psychobiol. 2009 Mar; 51(2):119-30.
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  493. Dierckx B, Tulen JH, van den Berg MP, Tharner A, Jaddoe VW, Moll HA, Hofman A, Verhulst FC, Tiemeier H. Maternal psychopathology influences infant heart rate variability: Generation R Study. Psychosom Med. 2009 Apr; 71(3):313-21.
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  494. Becker ML, Visser LE, van Schaik RH, Hofman A, Uitterlinden AG, Stricker BH. Genetic variation in the multidrug and toxin extrusion 1 transporter protein influences the glucose-lowering effect of metformin in patients with diabetes: a preliminary study. Diabetes. 2009 Mar; 58(3):745-9.
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  495. Aulchenko YS, Struchalin MV, Belonogova NM, Axenovich TI, Weedon MN, Hofman A, Uitterlinden AG, Kayser M, Oostra BA, van Duijn CM, Janssens AC, Borodin PM. Predicting human height by Victorian and genomic methods. Eur J Hum Genet. 2009 Aug; 17(8):1070-5.
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  496. Bijl MJ, van Schaik RH, Lammers LA, Hofman A, Vulto AG, van Gelder T, Stricker BH, Visser LE. The CYP2D6*4 polymorphism affects breast cancer survival in tamoxifen users. Breast Cancer Res Treat. 2009 Nov; 118(1):125-30.
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  497. Mook-Kanamori DO, Steegers EA, Uitterlinden AG, Moll HA, van Duijn CM, Hofman A, Jaddoe VW. Breast-feeding modifies the association of PPARgamma2 polymorphism Pro12Ala with growth in early life: the Generation R Study. Diabetes. 2009 Apr; 58(4):992-8.
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  498. van Meurs JB, Uitterlinden AG, Stolk L, Kerkhof HJ, Hofman A, Pols HA, Bierma-Zeinstra SM. A functional polymorphism in the catechol-O-methyltransferase gene is associated with osteoarthritis-related pain. Arthritis Rheum. 2009 Feb; 60(2):628-9.
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  499. van Durme YM, Verhamme KM, Stijnen T, van Rooij FJ, Van Pottelberge GR, Hofman A, Joos GF, Stricker BH, Brusselle GG. Prevalence, incidence, and lifetime risk for the development of COPD in the elderly: the Rotterdam study. Chest. 2009 Feb; 135(2):368-77.
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  500. van Noord C, Straus SM, Sturkenboom MC, Hofman A, Aarnoudse AJ, Bagnardi V, Kors JA, Newton-Cheh C, Witteman JC, Stricker BH. Psychotropic drugs associated with corrected QT interval prolongation. J Clin Psychopharmacol. 2009 Feb; 29(1):9-15.
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  501. Despriet DD, van Duijn CM, Oostra BA, Uitterlinden AG, Hofman A, Wright AF, ten Brink JB, Bakker A, de Jong PT, Vingerling JR, Bergen AA, Klaver CC. Complement component C3 and risk of age-related macular degeneration. Ophthalmology. 2009 Mar; 116(3):474-480.e2.
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  502. Lu TT, Lao O, Nothnagel M, Junge O, Freitag-Wolf S, Caliebe A, Balascakova M, Bertranpetit J, Bindoff LA, Comas D, Holmlund G, Kouvatsi A, Macek M, Mollet I, Nielsen F, Parson W, Palo J, Ploski R, Sajantila A, Tagliabracci A, Gether U, Werge T, Rivadeneira F, Hofman A, Uitterlinden AG, Gieger C, Wichmann HE, Ruether A, Schreiber S, Becker C, Nürnberg P, Nelson MR, Kayser M, Krawczak M. An evaluation of the genetic-matched pair study design using genome-wide SNP data from the European population. Eur J Hum Genet. 2009 Jul; 17(7):967-75.
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  503. de Lau LM, Koudstaal PJ, Hofman A, Breteler MM. [Parkinson disease is more prevalent than people think. Research results]. Ned Tijdschr Geneeskd. 2009 Jan 17; 153(3):63-8.
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  504. Zillikens MC, van Meurs JB, Sijbrands EJ, Rivadeneira F, Dehghan A, van Leeuwen JP, Hofman A, van Duijn CM, Witteman JC, Uitterlinden AG, Pols HA. SIRT1 genetic variation and mortality in type 2 diabetes: interaction with smoking and dietary niacin. Free Radic Biol Med. 2009 Mar 15; 46(6):836-41.
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  505. Omidvar M, Stolk L, Uitterlinden AG, Hofman A, Van Duijn CM, Tiemeier H. The effect of catechol-O-methyltransferase Met/Val functional polymorphism on smoking cessation: retrospective and prospective analyses in a cohort study. Pharmacogenet Genomics. 2009 Jan; 19(1):45-51.
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  506. Liu F, Ikram MA, Janssens AC, Schuur M, de Koning I, Isaacs A, Struchalin M, Uitterlinden AG, den Dunnen JT, Sleegers K, Bettens K, Van Broeckhoven C, van Swieten J, Hofman A, Oostra BA, Aulchenko YS, Breteler MM, van Duijn CM. A study of the SORL1 gene in Alzheimer's disease and cognitive function. J Alzheimers Dis. 2009; 18(1):51-64.
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  507. Hofman A, Breteler MM, van Duijn CM, Janssen HL, Krestin GP, Kuipers EJ, Stricker BH, Tiemeier H, Uitterlinden AG, Vingerling JR, Witteman JC. The Rotterdam Study: 2010 objectives and design update. Eur J Epidemiol. 2009; 24(9):553-72.
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  508. van Batenburg-Eddes T, de Groot L, Huizink AC, Steegers EA, Hofman A, Jaddoe VW, Verhulst FC, Tiemeier H. Maternal symptoms of anxiety during pregnancy affect infant neuromotor development: the generation R study. Dev Neuropsychol. 2009; 34(4):476-93.
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  509. Ikram MA, Liu F, Oostra BA, Hofman A, van Duijn CM, Breteler MM. The GAB2 gene and the risk of Alzheimer's disease: replication and meta-analysis. Biol Psychiatry. 2009 Jun 1; 65(11):995-9.
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  510. Jaddoe VW, van Duijn CM, van der Heijden AJ, Mackenbach JP, Moll HA, Steegers EA, Tiemeier H, Uitterlinden AG, Verhulst FC, Hofman A. The Generation R Study: design and cohort update until the age of 4 years. Eur J Epidemiol. 2008; 23(12):801-11.
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  511. van Durme YM, Verhamme KM, Aarnoudse AJ, Van Pottelberge GR, Hofman A, Witteman JC, Joos GF, Brusselle GG, Stricker BH. C-reactive protein levels, haplotypes, and the risk of incident chronic obstructive pulmonary disease. Am J Respir Crit Care Med. 2009 Mar 1; 179(5):375-82.
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  512. Holzhauer S, Hokken Koelega AC, Ridder Md, Hofman A, Moll HA, Steegers EA, Witteman JC, Jaddoe VW. Effect of birth weight and postnatal weight gain on body composition in early infancy: The Generation R Study. Early Hum Dev. 2009 May; 85(5):285-90.
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  513. Willer CJ, Speliotes EK, Loos RJ, Li S, Lindgren CM, Heid IM, Berndt SI, Elliott AL, Jackson AU, Lamina C, Lettre G, Lim N, Lyon HN, McCarroll SA, Papadakis K, Qi L, Randall JC, Roccasecca RM, Sanna S, Scheet P, Weedon MN, Wheeler E, Zhao JH, Jacobs LC, Prokopenko I, Soranzo N, Tanaka T, Timpson NJ, Almgren P, Bennett A, Bergman RN, Bingham SA, Bonnycastle LL, Brown M, Burtt NP, Chines P, Coin L, Collins FS, Connell JM, Cooper C, Smith GD, Dennison EM, Deodhar P, Elliott P, Erdos MR, Estrada K, Evans DM, Gianniny L, Gieger C, Gillson CJ, Guiducci C, Hackett R, Hadley D, Hall AS, Havulinna AS, Hebebrand J, Hofman A, Isomaa B, Jacobs KB, Johnson T, Jousilahti P, Jovanovic Z, Khaw KT, Kraft P, Kuokkanen M, Kuusisto J, Laitinen J, Lakatta EG, Luan J, Luben RN, Mangino M, McArdle WL, Meitinger T, Mulas A, Munroe PB, Narisu N, Ness AR, Northstone K, O'Rahilly S, Purmann C, Rees MG, Ridderstråle M, Ring SM, Rivadeneira F, Ruokonen A, Sandhu MS, Saramies J, Scott LJ, Scuteri A, Silander K, Sims MA, Song K, Stephens J, Stevens S, Stringham HM, Tung YC, Valle TT, Van Duijn CM, Vimaleswaran KS, Vollenweider P, Waeber G, Wallace C, Watanabe RM, Waterworth DM, Watkins N, Witteman JC, Zeggini E, Zhai G, Zillikens MC, Altshuler D, Caulfield MJ, Chanock SJ, Farooqi IS, Ferrucci L, Guralnik JM, Hattersley AT, Hu FB, Jarvelin MR, Laakso M, Mooser V, Ong KK, Ouwehand WH, Salomaa V, Samani NJ, Spector TD, Tuomi T, Tuomilehto J, Uda M, Uitterlinden AG, Wareham NJ, Deloukas P, Frayling TM, Groop LC, Hayes RB, Hunter DJ, Mohlke KL, Peltonen L, Schlessinger D, Strachan DP, Wichmann HE, McCarthy MI, Boehnke M, Barroso I, Abecasis GR, Hirschhorn JN. Six new loci associated with body mass index highlight a neuronal influence on body weight regulation. Nat Genet. 2009 Jan; 41(1):25-34.
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  514. Prokopenko I, Langenberg C, Florez JC, Saxena R, Soranzo N, Thorleifsson G, Loos RJ, Manning AK, Jackson AU, Aulchenko Y, Potter SC, Erdos MR, Sanna S, Hottenga JJ, Wheeler E, Kaakinen M, Lyssenko V, Chen WM, Ahmadi K, Beckmann JS, Bergman RN, Bochud M, Bonnycastle LL, Buchanan TA, Cao A, Cervino A, Coin L, Collins FS, Crisponi L, de Geus EJ, Dehghan A, Deloukas P, Doney AS, Elliott P, Freimer N, Gateva V, Herder C, Hofman A, Hughes TE, Hunt S, Illig T, Inouye M, Isomaa B, Johnson T, Kong A, Krestyaninova M, Kuusisto J, Laakso M, Lim N, Lindblad U, Lindgren CM, McCann OT, Mohlke KL, Morris AD, Naitza S, Orrù M, Palmer CN, Pouta A, Randall J, Rathmann W, Saramies J, Scheet P, Scott LJ, Scuteri A, Sharp S, Sijbrands E, Smit JH, Song K, Steinthorsdottir V, Stringham HM, Tuomi T, Tuomilehto J, Uitterlinden AG, Voight BF, Waterworth D, Wichmann HE, Willemsen G, Witteman JC, Yuan X, Zhao JH, Zeggini E, Schlessinger D, Sandhu M, Boomsma DI, Uda M, Spector TD, Penninx BW, Altshuler D, Vollenweider P, Jarvelin MR, Lakatta E, Waeber G, Fox CS, Peltonen L, Groop LC, Mooser V, Cupples LA, Thorsteinsdottir U, Boehnke M, Barroso I, Van Duijn C, Dupuis J, Watanabe RM, Stefansson K, McCarthy MI, Wareham NJ, Meigs JB, Abecasis GR. Variants in MTNR1B influence fasting glucose levels. Nat Genet. 2009 Jan; 41(1):77-81.
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  515. Aulchenko YS, Ripatti S, Lindqvist I, Boomsma D, Heid IM, Pramstaller PP, Penninx BW, Janssens AC, Wilson JF, Spector T, Martin NG, Pedersen NL, Kyvik KO, Kaprio J, Hofman A, Freimer NB, Jarvelin MR, Gyllensten U, Campbell H, Rudan I, Johansson A, Marroni F, Hayward C, Vitart V, Jonasson I, Pattaro C, Wright A, Hastie N, Pichler I, Hicks AA, Falchi M, Willemsen G, Hottenga JJ, de Geus EJ, Montgomery GW, Whitfield J, Magnusson P, Saharinen J, Perola M, Silander K, Isaacs A, Sijbrands EJ, Uitterlinden AG, Witteman JC, Oostra BA, Elliott P, Ruokonen A, Sabatti C, Gieger C, Meitinger T, Kronenberg F, Döring A, Wichmann HE, Smit JH, McCarthy MI, van Duijn CM, Peltonen L. Loci influencing lipid levels and coronary heart disease risk in 16 European population cohorts. Nat Genet. 2009 Jan; 41(1):47-55.
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  516. Luijendijk HJ, van den Berg JF, Dekker MJ, van Tuijl HR, Otte W, Smit F, Hofman A, Stricker BH, Tiemeier H. Incidence and recurrence of late-life depression. Arch Gen Psychiatry. 2008 Dec; 65(12):1394-401.
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  517. Becker ML, Visser LE, Newton-Cheh C, Hofman A, Uitterlinden AG, Witteman JC, Stricker BH. A common NOS1AP genetic polymorphism is associated with increased cardiovascular mortality in users of dihydropyridine calcium channel blockers. Br J Clin Pharmacol. 2009 Jan; 67(1):61-7.
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  518. Heeringa J, Hoogendoorn EH, van der Deure WM, Hofman A, Peeters RP, Hop WC, den Heijer M, Visser TJ, Witteman JC. High-normal thyroid function and risk of atrial fibrillation: the Rotterdam study. Arch Intern Med. 2008 Nov 10; 168(20):2219-24.
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  519. Johansson A, Marroni F, Hayward C, Franklin CS, Kirichenko AV, Jonasson I, Hicks AA, Vitart V, Isaacs A, Axenovich T, Campbell S, Dunlop MG, Floyd J, Hastie N, Hofman A, Knott S, Kolcic I, Pichler I, Polasek O, Rivadeneira F, Tenesa A, Uitterlinden AG, Wild SH, Zorkoltseva IV, Meitinger T, Wilson JF, Rudan I, Campbell H, Pattaro C, Pramstaller P, Oostra BA, Wright AF, van Duijn CM, Aulchenko YS, Gyllensten U. Common variants in the JAZF1 gene associated with height identified by linkage and genome-wide association analysis. Hum Mol Genet. 2009 Jan 15; 18(2):373-80.
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  520. Dehghan A, van Hoek M, Sijbrands EJ, Oostra BA, Hofman A, van Duijn CM, Witteman JC. Lack of association of two common polymorphisms on 9p21 with risk of coronary heart disease and myocardial infarction; results from a prospective cohort study. BMC Med. 2008; 6:30.
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  521. Eijgelsheim M, Aarnoudse AL, Rivadeneira F, Kors JA, Witteman JC, Hofman A, van Duijn CM, Uitterlinden AG, Stricker BH. Identification of a common variant at the NOS1AP locus strongly associated to QT-interval duration. Hum Mol Genet. 2009 Jan 15; 18(2):347-57.
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  522. van der Deure WM, Peeters RP, Uitterlinden AG, Hofman A, Breteler MM, Witteman J, Visser TJ. Impact of thyroid function and polymorphisms in the type 2 deiodinase on blood pressure: the Rotterdam Study and the Rotterdam Scan Study. Clin Endocrinol (Oxf). 2009 Jul; 71(1):137-44.
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  523. Heeringa J, Kors JA, Hofman A, van Rooij FJ, Witteman JC. Cigarette smoking and risk of atrial fibrillation: the Rotterdam Study. Am Heart J. 2008 Dec; 156(6):1163-9.
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  524. Geelhoed JJ, Verburg BO, Nauta J, Lequin M, Hofman A, Moll HA, Witteman JC, van der Heijden AJ, Steegers EA, Jaddoe VW. Tracking and determinants of kidney size from fetal life until the age of 2 years: the Generation R Study. Am J Kidney Dis. 2009 Feb; 53(2):248-58.
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  525. van den Berg JF, Miedema HM, Tulen JH, Neven AK, Hofman A, Witteman JC, Tiemeier H. Long sleep duration is associated with serum cholesterol in the elderly: the Rotterdam Study. Psychosom Med. 2008 Nov; 70(9):1005-11.
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  526. Dehghan A, Köttgen A, Yang Q, Hwang SJ, Kao WL, Rivadeneira F, Boerwinkle E, Levy D, Hofman A, Astor BC, Benjamin EJ, van Duijn CM, Witteman JC, Coresh J, Fox CS. Association of three genetic loci with uric acid concentration and risk of gout: a genome-wide association study. Lancet. 2008 Dec 6; 372(9654):1953-61.
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  527. Roza SJ, Steegers EA, Verburg BO, Jaddoe VW, Moll HA, Hofman A, Verhulst FC, Tiemeier H. What is spared by fetal brain-sparing? Fetal circulatory redistribution and behavioral problems in the general population. Am J Epidemiol. 2008 Nov 15; 168(10):1145-52.
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  528. Müskens RP, Wolfs RC, Witteman JC, Hofman A, de Jong PT, Stricker BH, Jansonius NM. Topical beta-blockers and mortality. Ophthalmology. 2008 Nov; 115(11):2037-43.
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  529. Verwoert GC, Mattace-Raso FU, Hofman A, Heeringa J, Stricker BH, Breteler MM, Witteman JC. Orthostatic hypotension and risk of cardiovascular disease in elderly people: the Rotterdam study. J Am Geriatr Soc. 2008 Oct; 56(10):1816-20.
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  530. Duijts L, Bakker-Jonges LE, Labout JA, Jaddoe VW, Hofman A, Steegers EA, van Dongen JJ, Hooijkaas H, Moll HA. Fetal growth influences lymphocyte subset counts at birth: the Generation R Study. Neonatology. 2009; 95(2):149-56.
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  531. Ye X, Pierik FH, Hauser R, Duty S, Angerer J, Park MM, Burdorf A, Hofman A, Jaddoe VW, Mackenbach JP, Steegers EA, Tiemeier H, Longnecker MP. Urinary metabolite concentrations of organophosphorous pesticides, bisphenol A, and phthalates among pregnant women in Rotterdam, the Netherlands: the Generation R study. Environ Res. 2008 Oct; 108(2):260-7.
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  532. Roza SJ, Verhulst FC, Jaddoe VW, Steegers EA, Mackenbach JP, Hofman A, Tiemeier H. Maternal smoking during pregnancy and child behaviour problems: the Generation R Study. Int J Epidemiol. 2009 Jun; 38(3):680-9.
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  533. Roza SJ, Govaert PP, Lequin MH, Jaddoe VW, Moll HA, Steegers EA, Hofman A, Verhulst FC, Tiemeier H. Cerebral ventricular volume and temperamental difficulties in infancy. The Generation R Study. J Psychiatry Neurosci. 2008 Sep; 33(5):431-9.
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  534. Silva LM, Steegers EA, Burdorf A, Jaddoe VW, Arends LR, Hofman A, Mackenbach JP, Raat H. No midpregnancy fall in diastolic blood pressure in women with a low educational level: the Generation R Study. Hypertension. 2008 Oct; 52(4):645-51.
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  535. Boekhoorn SS, Isaacs A, Uitterlinden AG, van Duijn CM, Hofman A, de Jong PT, Vingerling JR. Polymorphisms in the vascular endothelial growth factor gene and risk of age-related macular degeneration: the Rotterdam Study. Ophthalmology. 2008 Nov; 115(11):1899-903.
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  536. van Hoek M, Dehghan A, Witteman JC, van Duijn CM, Uitterlinden AG, Oostra BA, Hofman A, Sijbrands EJ, Janssens AC. Predicting type 2 diabetes based on polymorphisms from genome-wide association studies: a population-based study. Diabetes. 2008 Nov; 57(11):3122-8.
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  537. Lao O, Lu TT, Nothnagel M, Junge O, Freitag-Wolf S, Caliebe A, Balascakova M, Bertranpetit J, Bindoff LA, Comas D, Holmlund G, Kouvatsi A, Macek M, Mollet I, Parson W, Palo J, Ploski R, Sajantila A, Tagliabracci A, Gether U, Werge T, Rivadeneira F, Hofman A, Uitterlinden AG, Gieger C, Wichmann HE, Rüther A, Schreiber S, Becker C, Nürnberg P, Nelson MR, Krawczak M, Kayser M. Correlation between genetic and geographic structure in Europe. Curr Biol. 2008 Aug 26; 18(16):1241-8.
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  538. Cheung EY, Bos MJ, Leebeek FW, Koudstaal PJ, Hofman A, de Maat MP, Breteler MM. Variation in fibrinogen FGG and FGA genes and risk of stroke: the Rotterdam Study. Thromb Haemost. 2008 Aug; 100(2):308-13.
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  539. López-León S, Janssens AC, Tiemeier H, Hofman A, Aulchenko YS, Snijders PJ, Claes S, Oostra BA, van Duijn CM. Angiotensinogen M235T polymorphism and symptoms of depression in a population-based study and a family-based study. Psychiatr Genet. 2008 Aug; 18(4):162-6.
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  540. Ziere G, Dieleman JP, van der Cammen TJ, Hofman A, Pols HA, Stricker BH. Selective serotonin reuptake inhibiting antidepressants are associated with an increased risk of nonvertebral fractures. J Clin Psychopharmacol. 2008 Aug; 28(4):411-7.
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  541. Troe EJ, Raat H, Jaddoe VW, Hofman A, Steegers EA, Verhulst FC, Witteman JC, Mackenbach JP. Smoking during pregnancy in ethnic populations: the Generation R study. Nicotine Tob Res. 2008 Aug; 10(8):1373-84.
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  542. Lebon A, Labout JA, Verbrugh HA, Jaddoe VW, Hofman A, van Wamel W, Moll HA, van Belkum A. Dynamics and determinants of Staphylococcus aureus carriage in infancy: the Generation R Study. J Clin Microbiol. 2008 Oct; 46(10):3517-21.
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  543. Jansen PW, Raat H, Mackenbach JP, Jaddoe VW, Hofman A, Verhulst FC, Tiemeier H. Socioeconomic inequalities in infant temperament: the generation R study. Soc Psychiatry Psychiatr Epidemiol. 2009 Feb; 44(2):87-95.
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  544. van Dijk EJ, Prins ND, Vrooman HA, Hofman A, Koudstaal PJ, Breteler MM. Progression of cerebral small vessel disease in relation to risk factors and cognitive consequences: Rotterdam Scan study. Stroke. 2008 Oct; 39(10):2712-9.
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  545. Labout JA, Duijts L, Arends LR, Jaddoe VW, Hofman A, de Groot R, Verbrugh HA, Hermans PW, Moll HA. Factors associated with pneumococcal carriage in healthy Dutch infants: the generation R study. J Pediatr. 2008 Dec; 153(6):771-6.
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  546. El Marroun H, Tiemeier H, Jaddoe VW, Hofman A, Mackenbach JP, Steegers EA, Verhulst FC, van den Brink W, Huizink AC. Demographic, emotional and social determinants of cannabis use in early pregnancy: the Generation R study. Drug Alcohol Depend. 2008 Dec 1; 98(3):218-26.
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  547. Reitz C, van Rooij FJ, Soares HD, de Maat MP, Hofman A, Witteman JC, Breteler MM. Matrix metalloproteinase 3 haplotypes and plasma amyloid beta levels: the Rotterdam Study. Neurobiol Aging. 2010 Apr; 31(4):715-8.
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  548. Ho L, Boekhoorn SS, van Duijn CM, Uitterlinden AG, Hofman A, de Jong PT, Stijnen T, Vingerling JR. Cataract surgery and the risk of aging macula disorder: the rotterdam study. Invest Ophthalmol Vis Sci. 2008 Nov; 49(11):4795-800.
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  549. Timmermans S, Jaddoe VW, Mackenbach JP, Hofman A, Steegers-Theunissen RP, Steegers EA. Determinants of folic acid use in early pregnancy in a multi-ethnic urban population in The Netherlands: the Generation R study. Prev Med. 2008 Oct; 47(4):427-32.
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  550. Becker ML, Aarnoudse AJ, Newton-Cheh C, Hofman A, Witteman JC, Uitterlinden AG, Visser LE, Stricker BH. Common variation in the NOS1AP gene is associated with reduced glucose-lowering effect and with increased mortality in users of sulfonylurea. Pharmacogenet Genomics. 2008 Jul; 18(7):591-7.
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  551. Poels MM, Ikram MA, Vernooij MW, Krestin GP, Hofman A, Niessen WJ, van der Lugt A, Breteler MM. Total cerebral blood flow in relation to cognitive function: the Rotterdam Scan Study. J Cereb Blood Flow Metab. 2008 Oct; 28(10):1652-5.
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  552. Duijts L, Jaddoe VW, Hofman A, Steegers EA, Mackenbach JP, de Jongste JC, Moll HA. Maternal smoking in prenatal and early postnatal life and the risk of respiratory tract infections in infancy. The Generation R study. Eur J Epidemiol. 2008; 23(8):547-55.
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  553. van Batenburg-Eddes T, de Groot L, Arends L, de Vries A, Moll HA, Steegers EA, Hofman A, Jaddoe VW, Verhulst FC, Tiemeier H. Does gestational duration within the normal range predict infant neuromotor development? Early Hum Dev. 2008 Oct; 84(10):659-65.
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  554. van Houten VA, Mook-Kanamori DO, van Osch-Gevers L, Steegers EA, Hofman A, Moll HA, van Duijn CM, Helbing WA, Hokken-Koelega AC, Jaddoe VW. A variant of the IGF-I gene is associated with blood pressure but not with left heart dimensions at the age of 2 years: the Generation R Study. Eur J Endocrinol. 2008 Sep; 159(3):209-16.
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  555. Haag MD, Bos MJ, Hofman A, Koudstaal PJ, Breteler MM, Stricker BH. Cyclooxygenase selectivity of nonsteroidal anti-inflammatory drugs and risk of stroke. Arch Intern Med. 2008 Jun 9; 168(11):1219-24.
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  556. Schram MT, Frijters D, van de Lisdonk EH, Ploemacher J, de Craen AJ, de Waal MW, van Rooij FJ, Heeringa J, Hofman A, Deeg DJ, Schellevis FG. Setting and registry characteristics affect the prevalence and nature of multimorbidity in the elderly. J Clin Epidemiol. 2008 Nov; 61(11):1104-12.
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  557. Guelen I, Mattace-Raso FU, van Popele NM, Westerhof BE, Hofman A, Witteman JC, Bos WJ. Aortic stiffness and the balance between cardiac oxygen supply and demand: the Rotterdam Study. J Hypertens. 2008 Jun; 26(6):1237-43.
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  558. Boekhoorn SS, Vingerling JR, Hofman A, de Jong PT. Alcohol consumption and risk of aging macula disorder in a general population: the Rotterdam Study. Arch Ophthalmol. 2008 Jun; 126(6):834-9.
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  559. Silva LM, Coolman M, Steegers EA, Jaddoe VW, Moll HA, Hofman A, Mackenbach JP, Raat H. Low socioeconomic status is a risk factor for preeclampsia: the Generation R Study. J Hypertens. 2008 Jun; 26(6):1200-8.
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  560. Ikram MA, Vrooman HA, Vernooij MW, den Heijer T, Hofman A, Niessen WJ, van der Lugt A, Koudstaal PJ, Breteler MM. Brain tissue volumes in relation to cognitive function and risk of dementia. Neurobiol Aging. 2010 Mar; 31(3):378-86.
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  561. Duijts L, Bakker-Jonges LE, Mook-Kanamori DO, Labout JA, Hofman A, van Duijn CM, van Dongen JJ, Hooijkaas H, Moll HA, Jaddoe VW. Variation in the IGF-1 gene is associated with lymphocyte subset counts in neonates: the Generation R Study. Clin Endocrinol (Oxf). 2009 Jan; 70(1):53-9.
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  562. Valdes AM, Loughlin J, Timms KM, van Meurs JJ, Southam L, Wilson SG, Doherty S, Lories RJ, Luyten FP, Gutin A, Abkevich V, Ge D, Hofman A, Uitterlinden AG, Hart DJ, Zhang F, Zhai G, Egli RJ, Doherty M, Lanchbury J, Spector TD. Genome-wide association scan identifies a prostaglandin-endoperoxide synthase 2 variant involved in risk of knee osteoarthritis. Am J Hum Genet. 2008 Jun; 82(6):1231-40.
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  563. van Noord C, van der Deure WM, Sturkenboom MC, Straus SM, Hofman A, Visser TJ, Kors JA, Witteman JC, Stricker BH. High free thyroxine levels are associated with QTc prolongation in males. J Endocrinol. 2008 Jul; 198(1):253-60.
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  564. van der Hooft CS, Schoofs MW, Ziere G, Hofman A, Pols HA, Sturkenboom MC, Stricker BH. Inappropriate benzodiazepine use in older adults and the risk of fracture. Br J Clin Pharmacol. 2008 Aug; 66(2):276-82.
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  565. Emonts M, Uitterlinden AG, Nouwen JL, Kardys I, Maat MP, Melles DC, Witteman J, Jong PT, Verbrugh HA, Hofman A, Hermans PW, Belkum Av. Host polymorphisms in interleukin 4, complement factor H, and C-reactive protein associated with nasal carriage of Staphylococcus aureus and occurrence of boils. J Infect Dis. 2008 May 1; 197(9):1244-53.
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  566. Euser SM, Schram MT, Hofman A, Westendorp RG, Breteler MM. Measuring cognitive function with age: the influence of selection by health and survival. Epidemiology. 2008 May; 19(3):440-7.
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  567. Verburg BO, Mulder PG, Hofman A, Jaddoe VW, Witteman JC, Steegers EA. Intra- and interobserver reproducibility study of early fetal growth parameters. Prenat Diagn. 2008 Apr; 28(4):323-31.
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  568. Aarnoudse AJ, Dieleman JP, Visser LE, Arp PP, van der Heiden IP, van Schaik RH, Molokhia M, Hofman A, Uitterlinden AG, Stricker BH. Common ATP-binding cassette B1 variants are associated with increased digoxin serum concentration. Pharmacogenet Genomics. 2008 Apr; 18(4):299-305.
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  569. Arias-Vásquez A, Aulchenko YS, Isaacs A, van Oosterhout A, Sleegers K, Hofman A, van Broeckhoven C, Oostra BA, Breteler M, van Duijn CM. Cyclin-dependent kinase 5 is associated with risk for Alzheimer's disease in a Dutch population-based study. J Neurol. 2008 May; 255(5):655-62.
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  570. van Meurs JB, Trikalinos TA, Ralston SH, Balcells S, Brandi ML, Brixen K, Kiel DP, Langdahl BL, Lips P, Ljunggren O, Lorenc R, Obermayer-Pietsch B, Ohlsson C, Pettersson U, Reid DM, Rousseau F, Scollen S, Van Hul W, Agueda L, Akesson K, Benevolenskaya LI, Ferrari SL, Hallmans G, Hofman A, Husted LB, Kruk M, Kaptoge S, Karasik D, Karlsson MK, Lorentzon M, Masi L, McGuigan FE, Mellström D, Mosekilde L, Nogues X, Pols HA, Reeve J, Renner W, Rivadeneira F, van Schoor NM, Weber K, Ioannidis JP, Uitterlinden AG. Large-scale analysis of association between LRP5 and LRP6 variants and osteoporosis. JAMA. 2008 Mar 19; 299(11):1277-90.
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  571. Ikram MA, van Oijen M, de Jong FJ, Kors JA, Koudstaal PJ, Hofman A, Witteman JC, Breteler MM. Unrecognized myocardial infarction in relation to risk of dementia and cerebral small vessel disease. Stroke. 2008 May; 39(5):1421-6.
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  572. van Woudenbergh GJ, Vliegenthart R, van Rooij FJ, Hofman A, Oudkerk M, Witteman JC, Geleijnse JM. Coffee consumption and coronary calcification: the Rotterdam Coronary Calcification Study. Arterioscler Thromb Vasc Biol. 2008 May; 28(5):1018-23.
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  573. Kardys I, Deckers JW, Stricker BH, Vletter WB, Hofman A, Witteman JC. Echocardiographic parameters and all-cause mortality: the Rotterdam Study. Int J Cardiol. 2009 Apr 3; 133(2):198-204.
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  574. Roza SJ, van Lier PA, Jaddoe VW, Steegers EA, Moll HA, Mackenbach JP, Hofman A, Verhulst FC, Tiemeier H. Intrauterine growth and infant temperamental difficulties: the Generation R Study. J Am Acad Child Adolesc Psychiatry. 2008 Mar; 47(3):264-72.
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  575. Duijts L, Bakker-Jonges LE, Labout JA, Jaddoe VW, Hofman A, Steegers EA, Van Dongen JJ, Hooijkaas H, Moll HA. Perinatal stress influences lymphocyte subset counts in neonates. The generation R study. Pediatr Res. 2008 Mar; 63(3):292-8.
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  576. Jaddoe VW, Troe EJ, Hofman A, Mackenbach JP, Moll HA, Steegers EA, Witteman JC. Active and passive maternal smoking during pregnancy and the risks of low birthweight and preterm birth: the Generation R Study. Paediatr Perinat Epidemiol. 2008 Mar; 22(2):162-71.
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  577. Bos MJ, Schuit SC, Koudstaal PJ, Hofman A, Uitterlinden AG, Breteler MM. Variation in the estrogen receptor alpha gene and risk of stroke: the Rotterdam Study. Stroke. 2008 Apr; 39(4):1324-6.
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  578. Van Den Berg JF, Van Rooij FJ, Vos H, Tulen JH, Hofman A, Miedema HM, Neven AK, Tiemeier H. Disagreement between subjective and actigraphic measures of sleep duration in a population-based study of elderly persons. J Sleep Res. 2008 Sep; 17(3):295-302.
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  579. van der Knaap R, Siemes C, Coebergh JW, van Duijn CM, Hofman A, Stricker BH. Renin-angiotensin system inhibitors, angiotensin I-converting enzyme gene insertion/deletion polymorphism, and cancer: the Rotterdam Study. Cancer. 2008 Feb 15; 112(4):748-57.
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  580. Kayser M, Liu F, Janssens AC, Rivadeneira F, Lao O, van Duijn K, Vermeulen M, Arp P, Jhamai MM, van Ijcken WF, den Dunnen JT, Heath S, Zelenika D, Despriet DD, Klaver CC, Vingerling JR, de Jong PT, Hofman A, Aulchenko YS, Uitterlinden AG, Oostra BA, van Duijn CM. Three genome-wide association studies and a linkage analysis identify HERC2 as a human iris color gene. Am J Hum Genet. 2008 Feb; 82(2):411-23.
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  581. Verburg BO, Jaddoe VW, Wladimiroff JW, Hofman A, Witteman JC, Steegers EA. Fetal hemodynamic adaptive changes related to intrauterine growth: the Generation R Study. Circulation. 2008 Feb 5; 117(5):649-59.
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  582. van den Akker EL, Koper JW, van Rossum EF, Dekker MJ, Russcher H, de Jong FH, Uitterlinden AG, Hofman A, Pols HA, Witteman JC, Lamberts SW. Glucocorticoid receptor gene and risk of cardiovascular disease. Arch Intern Med. 2008 Jan 14; 168(1):33-9.
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  583. Becker ML, Visser LE, van Gelder T, Hofman A, Stricker BH. Increasing exposure to drug-drug interactions between 1992 and 2005 in people aged > or = 55 years. Drugs Aging. 2008; 25(2):145-52.
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  584. Yazdanpanah N, Uitterlinden AG, Zillikens MC, Jhamai M, Rivadeneira F, Hofman A, de Jonge R, Lindemans J, Pols HA, van Meurs JB. Low dietary riboflavin but not folate predicts increased fracture risk in postmenopausal women homozygous for the MTHFR 677 T allele. J Bone Miner Res. 2008 Jan; 23(1):86-94.
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  585. Geelhoed JJ, VAN Osch-Gevers L, Verburg BO, Steegers EA, Hofman A, Helbing W, Witteman JC, Jaddoe VW. Maternal anthropometrics in pregnancy are associated with left ventricular mass in infancy. The generation R study. Pediatr Res. 2008 Jan; 63(1):62-6.
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  586. de Voogd S, Wolfs RC, Jansonius NM, Uitterlinden AG, Pols HA, Hofman A, de Jong PT. Estrogen receptors alpha and beta and the risk of open-angle glaucoma: the Rotterdam Study. Arch Ophthalmol. 2008 Jan; 126(1):110-4.
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  587. Sie MP, Mattace-Raso FU, Uitterlinden AG, Arp PP, Hofman A, Pols HA, Hoeks AP, Reneman RS, Asmar R, van Duijn CM, Witteman JC. The interleukin-6-174 G/C promoter polymorphism and arterial stiffness; the Rotterdam Study. Vasc Health Risk Manag. 2008; 4(4):863-9.
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  588. Pardo Silva MC, Janssens AC, Hofman A, Witteman JC, van Duijn CM. Apolipoprotein E gene is related to mortality only in normal weight individuals: the Rotterdam Study. Eur J Epidemiol. 2008; 23(2):135-42.
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  589. Bos MJ, van Rijn MJ, Witteman JC, Hofman A, Koudstaal PJ, Breteler MM. Incidence and prognosis of transient neurological attacks. JAMA. 2007 Dec 26; 298(24):2877-85.
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  590. Jaddoe VW, Bakker R, van Duijn CM, van der Heijden AJ, Lindemans J, Mackenbach JP, Moll HA, Steegers EA, Tiemeier H, Uitterlinden AG, Verhulst FC, Hofman A. The Generation R Study Biobank: a resource for epidemiological studies in children and their parents. Eur J Epidemiol. 2007; 22(12):917-23.
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  591. Luijendijk HJ, Tiemeier H, Hofman A, Heeringa J, Stricker BH. Determinants of chronic benzodiazepine use in the elderly: a longitudinal study. Br J Clin Pharmacol. 2008 Apr; 65(4):593-9.
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  592. de Jong FJ, Vernooij MW, Ikram MK, Ikram MA, Hofman A, Krestin GP, van der Lugt A, de Jong PT, Breteler MM. Arteriolar oxygen saturation, cerebral blood flow, and retinal vessel diameters. The Rotterdam Study. Ophthalmology. 2008 May; 115(5):887-92.
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  593. Bijl MJ, Visser LE, Hofman A, Vulto AG, van Gelder T, Stricker BH, van Schaik RH. Influence of the CYP2D6*4 polymorphism on dose, switching and discontinuation of antidepressants. Br J Clin Pharmacol. 2008 Apr; 65(4):558-64.
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  594. Mook-Kanamori DO, Miranda Geelhoed JJ, Steegers EA, Witteman JC, Hofman A, Moll HA, van Duijn CM, Hokken-Koelega AC, Jaddoe VW. Insulin gene variable number of tandem repeats is not associated with weight from fetal life until infancy: the Generation R Study. Eur J Endocrinol. 2007 Dec; 157(6):741-8.
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  595. Ikram MA, Vernooij MW, Hofman A, Niessen WJ, van der Lugt A, Breteler MM. Kidney function is related to cerebral small vessel disease. Stroke. 2008 Jan; 39(1):55-61.
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  596. Roza SJ, Govaert PP, Vrooman HA, Lequin MH, Hofman A, Steegers EA, Moll HA, Jaddoe VW, Verhulst FC, Tiemeier H. Foetal growth determines cerebral ventricular volume in infants The Generation R Study. Neuroimage. 2008 Feb 15; 39(4):1491-8.
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  597. Reitz C, Bos MJ, Hofman A, Koudstaal PJ, Breteler MM. Prestroke cognitive performance, incident stroke, and risk of dementia: the Rotterdam Study. Stroke. 2008 Jan; 39(1):36-41.
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  598. Rivadeneira F, Zillikens MC, De Laet CE, Hofman A, Uitterlinden AG, Beck TJ, Pols HA. Femoral neck BMD is a strong predictor of hip fracture susceptibility in elderly men and women because it detects cortical bone instability: the Rotterdam Study. J Bone Miner Res. 2007 Nov; 22(11):1781-90.
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  599. Schram MT, Trompet S, Kamper AM, de Craen AJ, Hofman A, Euser SM, Breteler MM, Westendorp RG. Serum calcium and cognitive function in old age. J Am Geriatr Soc. 2007 Nov; 55(11):1786-92.
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  600. Vernooij MW, Ikram MA, Tanghe HL, Vincent AJ, Hofman A, Krestin GP, Niessen WJ, Breteler MM, van der Lugt A. Incidental findings on brain MRI in the general population. N Engl J Med. 2007 Nov 1; 357(18):1821-8.
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  601. Dehghan A, van Hoek M, Sijbrands EJ, Hofman A, Witteman JC. High serum uric acid as a novel risk factor for type 2 diabetes. Diabetes Care. 2008 Feb; 31(2):361-2.
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  602. Bos MJ, Koudstaal PJ, Hofman A, Breteler MM. Decreased glomerular filtration rate is a risk factor for hemorrhagic but not for ischemic stroke: the Rotterdam Study. Stroke. 2007 Dec; 38(12):3127-32.
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  603. Stolk L, van Meurs JB, Arp PP, Hofman A, Pols HA, Uitterlinden AG. The RIZ Pro704 insertion-deletion polymorphism, bone mineral density and fracture risk: the Rotterdam study. Bone. 2008 Feb; 42(2):286-93.
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  604. Hofman A, Breteler MM, van Duijn CM, Krestin GP, Pols HA, Stricker BH, Tiemeier H, Uitterlinden AG, Vingerling JR, Witteman JC. The Rotterdam Study: objectives and design update. Eur J Epidemiol. 2007; 22(11):819-29.
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  605. Boekhoorn SS, Vingerling JR, Witteman JC, Hofman A, de Jong PT. C-reactive protein level and risk of aging macula disorder: The Rotterdam Study. Arch Ophthalmol. 2007 Oct; 125(10):1396-401.
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  606. Geleijnse JM, Witteman JC, Stijnen T, Kloos MW, Hofman A, Grobbee DE. Sodium and potassium intake and risk of cardiovascular events and all-cause mortality: the Rotterdam Study. Eur J Epidemiol. 2007; 22(11):763-70.
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  607. Geelhoed JJ, Mook-Kanamori DO, Witteman JC, Hofman A, van Duijn CM, Moll HA, Steegers EA, Hokken-Koelega AC, Jaddoe VW. Variation in the IGF1 gene and growth in foetal life and infancy. The Generation R Study. Clin Endocrinol (Oxf). 2008 Mar; 68(3):382-9.
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  608. Bornebroek M, de Lau LM, Haag MD, Koudstaal PJ, Hofman A, Stricker BH, Breteler MM. Nonsteroidal anti-inflammatory drugs and the risk of Parkinson disease. Neuroepidemiology. 2007; 28(4):193-6.
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  609. Aulchenko YS, Pullen J, Kloosterman WP, Yazdanpanah M, Hofman A, Vaessen N, Snijders PJ, Zubakov D, Mackay I, Olavesen M, Sidhu B, Smith VE, Carey A, Berezikov E, Uitterlinden AG, Plasterk RH, Oostra BA, van Duijn CM. LPIN2 is associated with type 2 diabetes, glucose metabolism, and body composition. Diabetes. 2007 Dec; 56(12):3020-6.
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  610. Ikram MA, Vernooij MW, Vrooman HA, Hofman A, Breteler MM. Brain tissue volumes and small vessel disease in relation to the risk of mortality. Neurobiol Aging. 2009 Mar; 30(3):450-6.
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  611. van der Deure WM, Uitterlinden AG, Hofman A, Rivadeneira F, Pols HA, Peeters RP, Visser TJ. Effects of serum TSH and FT4 levels and the TSHR-Asp727Glu polymorphism on bone: the Rotterdam Study. Clin Endocrinol (Oxf). 2008 Feb; 68(2):175-81.
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  612. Silva MC, Janssens AC, Hofman A, Witteman JC, van Duijn CM. Cholesteryl ester transfer protein gene and coronary heart disease mortality: the Rotterdam study. J Am Geriatr Soc. 2007 Sep; 55(9):1483-4.
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  613. Elias-Smale SE, Kardys I, Oudkerk M, Hofman A, Witteman JC. C-reactive protein is related to extent and progression of coronary and extra-coronary atherosclerosis; results from the Rotterdam study. Atherosclerosis. 2007 Dec; 195(2):e195-202.
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  614. Bos MJ, Koudstaal PJ, Hofman A, Witteman JC, Breteler MM. Transcranial Doppler hemodynamic parameters and risk of stroke: the Rotterdam study. Stroke. 2007 Sep; 38(9):2453-8.
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  615. Arias-Vásquez A, de Lau L, Pardo L, Liu F, Feng BJ, Bertoli-Avella A, Isaacs A, Aulchenko Y, Hofman A, Oostra B, Breteler M, van Duijn C. Relationship of the Ubiquilin 1 gene with Alzheimer's and Parkinson's disease and cognitive function. Neurosci Lett. 2007 Aug 31; 424(1):1-5.
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  616. van den Berg JF, Tulen JH, Neven AK, Hofman A, Miedema HM, Witteman JC, Tiemeier H. Sleep duration and hypertension are not associated in the elderly. Hypertension. 2007 Sep; 50(3):585-9.
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  617. Vernooij MW, van der Lugt A, Ikram MA, Wielopolski PA, Vrooman HA, Hofman A, Krestin GP, Breteler MM. Total cerebral blood flow and total brain perfusion in the general population: the Rotterdam Scan Study. J Cereb Blood Flow Metab. 2008 Feb; 28(2):412-9.
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  618. Dehghan A, van Hoek M, Sijbrands EJ, Stijnen T, Hofman A, Witteman JC. Risk of type 2 diabetes attributable to C-reactive protein and other risk factors. Diabetes Care. 2007 Oct; 30(10):2695-9.
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  619. Visser LE, van Schaik RH, Jan Danser AH, Hofman A, Witteman JC, van Duijn CM, Uitterlinden AG, Pols HA, Stricker BH. The risk of myocardial infarction in patients with reduced activity of cytochrome P450 2C9. Pharmacogenet Genomics. 2007 Jul; 17(7):473-9.
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  620. de Jong FJ, Ikram MK, Despriet DD, Uitterlinden AG, Hofman A, Breteler MM, de Jong PT. Complement factor h polymorphism, inflammatory mediators, and retinal vessel diameters: the rotterdam study. Invest Ophthalmol Vis Sci. 2007 Jul; 48(7):3014-8.
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  621. Mattace-Raso FU, van den Meiracker AH, Bos WJ, van der Cammen TJ, Westerhof BE, Elias-Smale S, Reneman RS, Hoeks AP, Hofman A, Witteman JC. Arterial stiffness, cardiovagal baroreflex sensitivity and postural blood pressure changes in older adults: the Rotterdam Study. J Hypertens. 2007 Jul; 25(7):1421-6.
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  622. Jaddoe VW, Bakker R, Hofman A, Mackenbach JP, Moll HA, Steegers EA, Witteman JC. Moderate alcohol consumption during pregnancy and the risk of low birth weight and preterm birth. The generation R study. Ann Epidemiol. 2007 Oct; 17(10):834-40.
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  623. Kardys I, de Maat MP, Klaver CC, Despriet DD, Uitterlinden AG, Hofman A, de Jong PT, Witteman JC. Usefulness of combining complement factor H and C-reactive protein genetic profiles for predicting myocardial infarction (from the Rotterdam Study). Am J Cardiol. 2007 Aug 15; 100(4):646-8.
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  624. Aarnoudse AJ, Newton-Cheh C, de Bakker PI, Straus SM, Kors JA, Hofman A, Uitterlinden AG, Witteman JC, Stricker BH. Common NOS1AP variants are associated with a prolonged QTc interval in the Rotterdam Study. Circulation. 2007 Jul 3; 116(1):10-6.
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  625. Müskens RP, de Voogd S, Wolfs RC, Witteman JC, Hofman A, de Jong PT, Stricker BH, Jansonius NM. Systemic antihypertensive medication and incident open-angle glaucoma. Ophthalmology. 2007 Dec; 114(12):2221-6.
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  626. Kardys I, Vliegenthart R, Oudkerk M, Hofman A, Witteman JC. The female advantage in cardiovascular disease: do vascular beds contribute equally? Am J Epidemiol. 2007 Aug 15; 166(4):403-12.
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  627. Yazdanpanah N, Rivadeneira F, van Meurs JB, Zillikens MC, Arp P, Hofman A, van Duijn CM, Pols HA, Uitterlinden AG. The -1997 G/T and Sp1 polymorphisms in the collagen type I alpha1 (COLIA1) gene in relation to changes in femoral neck bone mineral density and the risk of fracture in the elderly: the Rotterdam study. Calcif Tissue Int. 2007 Jul; 81(1):18-25.
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  628. Isaacs A, Sayed-Tabatabaei FA, Hofman A, Oostra BA, Klungel OH, Maitland-Vander Zee AH, Stricker BH, Witteman JC, van Duijn CM. The cholesteryl ester transfer protein I405V polymorphism is associated with increased high-density lipoprotein levels and decreased risk of myocardial infarction: the Rotterdam Study. Eur J Cardiovasc Prev Rehabil. 2007 Jun; 14(3):419-21.
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  629. Hulsman CA, Vingerling JR, Hofman A, Witteman JC, de Jong PT. Blood pressure, arterial stiffness, and open-angle glaucoma: the Rotterdam study. Arch Ophthalmol. 2007 Jun; 125(6):805-12.
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  630. van Leeuwen R, Eijkemans MJ, Vingerling JR, Hofman A, de Jong PT, Simonsz HJ. Risk of bilateral visual impairment in individuals with amblyopia: the Rotterdam study. Br J Ophthalmol. 2007 Nov; 91(11):1450-1.
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  631. Stolk L, van Meurs JB, Jhamai M, Arp PP, van Leeuwen JP, Hofman A, de Jong FH, Pols HA, Uitterlinden AG. The catechol-O-methyltransferase Met158 low-activity allele and association with nonvertebral fracture risk in elderly men. J Clin Endocrinol Metab. 2007 Aug; 92(8):3206-12.
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  632. Arias-Vásquez A, Isaacs A, Aulchenko YS, Hofman A, Oostra BA, Breteler M, van Duijn CM. The cholesteryl ester transfer protein (CETP) gene and the risk of Alzheimer's disease. Neurogenetics. 2007 Aug; 8(3):189-93.
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  633. de Jong FJ, Ikram MK, Witteman JC, Hofman A, de Jong PT, Breteler MM. Retinal vessel diameters and the role of inflammation in cerebrovascular disease. Ann Neurol. 2007 May; 61(5):491-5.
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  634. Schram MT, Euser SM, de Craen AJ, Witteman JC, Frölich M, Hofman A, Jolles J, Breteler MM, Westendorp RG. Systemic markers of inflammation and cognitive decline in old age. J Am Geriatr Soc. 2007 May; 55(5):708-16.
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  635. van Oijen M, de Jong FJ, Witteman JC, Hofman A, Koudstaal PJ, Breteler MM. Atherosclerosis and risk for dementia. Ann Neurol. 2007 May; 61(5):403-10.
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  636. Yazdanpanah M, Aulchenko YS, Hofman A, Janssen JA, Sayed-Tabatabaei FA, van Schaik RH, Klungel OH, Stricker BH, Pols HA, Witteman JC, Lamberts SW, Oostra BA, van Duijn CM. Effects of the renin-angiotensin system genes and salt sensitivity genes on blood pressure and atherosclerosis in the total population and patients with type 2 diabetes. Diabetes. 2007 Jul; 56(7):1905-12.
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  637. Isaacs A, Aulchenko YS, Hofman A, Sijbrands EJ, Sayed-Tabatabaei FA, Klungel OH, Maitland-van der Zee AH, Stricker BH, Oostra BA, Witteman JC, van Duijn CM. Epistatic effect of cholesteryl ester transfer protein and hepatic lipase on serum high-density lipoprotein cholesterol levels. J Clin Endocrinol Metab. 2007 Jul; 92(7):2680-7.
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  638. van Oijen M, de Jong FJ, Hofman A, Koudstaal PJ, Breteler MM. Subjective memory complaints, education, and risk of Alzheimer's disease. Alzheimers Dement. 2007 Apr; 3(2):92-7.
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  639. Jaddoe VW, de Ridder MA, van den Elzen AP, Hofman A, Uiterwaal CS, Witteman JC. Maternal smoking in pregnancy is associated with cholesterol development in the offspring: A 27-years follow-up study. Atherosclerosis. 2008 Jan; 196(1):42-8.
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  640. Boekhoorn SS, Vingerling JR, Uitterlinden AG, Van Meurs JB, van Duijn CM, Pols HA, Hofman A, de Jong PT. Estrogen receptor alpha gene polymorphisms associated with incident aging macula disorder. Invest Ophthalmol Vis Sci. 2007 Mar; 48(3):1012-7.
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  641. Dehghan A, Kardys I, de Maat MP, Uitterlinden AG, Sijbrands EJ, Bootsma AH, Stijnen T, Hofman A, Schram MT, Witteman JC. Genetic variation, C-reactive protein levels, and incidence of diabetes. Diabetes. 2007 Mar; 56(3):872-8.
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  642. Jaddoe VW, Verburg BO, de Ridder MA, Hofman A, Mackenbach JP, Moll HA, Steegers EA, Witteman JC. Maternal smoking and fetal growth characteristics in different periods of pregnancy: the generation R study. Am J Epidemiol. 2007 May 15; 165(10):1207-15.
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  643. Heeringa J, van der Kuip DA, Hofman A, Kors JA, van Rooij FJ, Lip GY, Witteman JC. Subclinical atherosclerosis and risk of atrial fibrillation: the rotterdam study. Arch Intern Med. 2007 Feb 26; 167(4):382-7.
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  644. Reitz C, van Rooij FJ, de Maat MP, den Heijer T, Hofman A, Witteman JC, Breteler MM. Matrix metalloproteinase 3 haplotypes and dementia and Alzheimer's disease. The Rotterdam Study. Neurobiol Aging. 2008 Jun; 29(6):874-81.
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  645. Schelleman H, Klungel OH, Witteman JC, Breteler MM, Yazdanpanah M, Danser AH, Hofman A, van Duijn CM, de Boer A, Stricker BH. Angiotensinogen M235T polymorphism and the risk of myocardial infarction and stroke among hypertensive patients on ACE-inhibitors or beta-blockers. Eur J Hum Genet. 2007 Apr; 15(4):478-84.
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  646. Roza SJ, Verburg BO, Jaddoe VW, Hofman A, Mackenbach JP, Steegers EA, Witteman JC, Verhulst FC, Tiemeier H. Effects of maternal smoking in pregnancy on prenatal brain development. The Generation R Study. Eur J Neurosci. 2007 Feb; 25(3):611-7.
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  647. Collaborative meta-analysis of individual participant data from observational studies of Lp-PLA2 and cardiovascular diseases. Eur J Cardiovasc Prev Rehabil. 2007 Feb; 14(1):3-11.
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  648. Kardys I, Uitterlinden AG, Hofman A, Witteman JC, de Maat MP. Fibrinogen gene haplotypes in relation to risk of coronary events and coronary and extracoronary atherosclerosis: the Rotterdam Study. Thromb Haemost. 2007 Feb; 97(2):288-95.
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  649. Poels MM, van Oijen M, Mattace-Raso FU, Hofman A, Koudstaal PJ, Witteman JC, Breteler MM. Arterial stiffness, cognitive decline, and risk of dementia: the Rotterdam study. Stroke. 2007 Mar; 38(3):888-92.
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  650. Ikram MA, Vrooman HA, Vernooij MW, van der Lijn F, Hofman A, van der Lugt A, Niessen WJ, Breteler MM. Brain tissue volumes in the general elderly population. The Rotterdam Scan Study. Neurobiol Aging. 2008 Jun; 29(6):882-90.
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  651. Teichert M, de Smet PA, Hofman A, Witteman JC, Stricker BH. Discontinuation of beta-blockers and the risk of myocardial infarction in the elderly. Drug Saf. 2007; 30(6):541-9.
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  652. Tas U, Verhagen AP, Bierma-Zeinstra SM, Hofman A, Odding E, Pols HA, Koes BW. Incidence and risk factors of disability in the elderly: the Rotterdam Study. Prev Med. 2007 Mar; 44(3):272-8.
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  653. van Rossum EF, de Jong FJ, Koper JW, Uitterlinden AG, Prins ND, van Dijk EJ, Koudstaal PJ, Hofman A, de Jong FH, Lamberts SW, Breteler MM. Glucocorticoid receptor variant and risk of dementia and white matter lesions. Neurobiol Aging. 2008 May; 29(5):716-23.
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  654. van Popele NM, Mattace-Raso FU, Vliegenthart R, Grobbee DE, Asmar R, van der Kuip DA, Hofman A, de Feijter PJ, Oudkerk M, Witteman JC. Aortic stiffness is associated with atherosclerosis of the coronary arteries in older adults: the Rotterdam Study. J Hypertens. 2006 Dec; 24(12):2371-6.
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  655. López-León S, Janssens AC, Hofman A, Claes S, Breteler MM, Tiemeier H, van Duijn CM. No association between the angiotensin-converting enzyme gene and major depression: a case-control study and meta-analysis. Psychiatr Genet. 2006 Dec; 16(6):225-6.
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  656. Siemes C, Visser LE, Coebergh JW, Splinter TA, Witteman JC, Uitterlinden AG, Hofman A, Pols HA, Stricker BH. C-reactive protein levels, variation in the C-reactive protein gene, and cancer risk: the Rotterdam Study. J Clin Oncol. 2006 Nov 20; 24(33):5216-22.
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  657. de Jong FJ, Peeters RP, den Heijer T, van der Deure WM, Hofman A, Uitterlinden AG, Visser TJ, Breteler MM. The association of polymorphisms in the type 1 and 2 deiodinase genes with circulating thyroid hormone parameters and atrophy of the medial temporal lobe. J Clin Endocrinol Metab. 2007 Feb; 92(2):636-40.
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  658. van Rijn MJ, Bos MJ, Yazdanpanah M, Isaacs A, Arias-Vásquez A, Koudstaal PJ, Hofman A, Witteman JC, van Duijn CM, Breteler MM. Alpha-adducin polymorphism, atherosclerosis, and cardiovascular and cerebrovascular risk. Stroke. 2006 Dec; 37(12):2930-4.
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  659. Yazdanpanah M, Sayed-Tabatabaei FA, Janssen JA, Rietveld I, Hofman A, Stijnen T, Pols HA, Lamberts SW, Witteman JC, van Duijn CM. IGF-I gene promoter polymorphism is a predictor of survival after myocardial infarction in patients with type 2 diabetes. Eur J Endocrinol. 2006 Nov; 155(5):751-6.
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  660. Tiemeier H, Fekkes D, Hofman A, van Tuijl HR, Kiliaan AJ, Breteler MM. Plasma pterins and folate in late life depression: the Rotterdam Study. Psychiatry Res. 2006 Dec 7; 145(2-3):199-206.
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  661. Sie MP, Uitterlinden AG, Bos MJ, Arp PP, Breteler MM, Koudstaal PJ, Pols HA, Hofman A, van Duijn CM, Witteman JC. TGF-beta 1 polymorphisms and risk of myocardial infarction and stroke: the Rotterdam Study. Stroke. 2006 Nov; 37(11):2667-71.
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  662. Bos MJ, Schipper CM, Koudstaal PJ, Witteman JC, Hofman A, Breteler MM. High serum C-reactive protein level is not an independent predictor for stroke: the Rotterdam Study. Circulation. 2006 Oct 10; 114(15):1591-8.
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  663. Yazdanpanah M, Sayed-Tabatabaei FA, Hofman A, Aulchenko YS, Oostra BA, Stricker BH, Pols HA, Lamberts SW, Witteman JC, Janssen JA, van Duijn CM. The alpha-adducin gene is associated with macrovascular complications and mortality in patients with type 2 diabetes. Diabetes. 2006 Oct; 55(10):2922-7.
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  664. van Vark LC, Kardys I, Bleumink GS, Knetsch AM, Deckers JW, Hofman A, Stricker BH, Witteman JC. Lipoprotein-associated phospholipase A2 activity and risk of heart failure: The Rotterdam study. Eur Heart J. 2006 Oct; 27(19):2346-52.
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  665. Rivadeneira F, van Meurs JB, Kant J, Zillikens MC, Stolk L, Beck TJ, Arp P, Schuit SC, Hofman A, Houwing-Duistermaat JJ, van Duijn CM, van Leeuwen JP, Pols HA, Uitterlinden AG. Estrogen receptor beta (ESR2) polymorphisms in interaction with estrogen receptor alpha (ESR1) and insulin-like growth factor I (IGF1) variants influence the risk of fracture in postmenopausal women. J Bone Miner Res. 2006 Sep; 21(9):1443-56.
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  666. Kardys I, Knetsch AM, Bleumink GS, Deckers JW, Hofman A, Stricker BH, Witteman JC. C-reactive protein and risk of heart failure. The Rotterdam Study. Am Heart J. 2006 Sep; 152(3):514-20.
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  667. de Voogd S, Wolfs RC, Jansonius NM, Witteman JC, Hofman A, de Jong PT. Atherosclerosis, C-reactive protein, and risk for open-angle glaucoma: the Rotterdam study. Invest Ophthalmol Vis Sci. 2006 Sep; 47(9):3772-6.
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  668. Hak AE, Westendorp IC, Pols HA, Hofman A, Witteman JC. High-dose testosterone is associated with atherosclerosis in postmenopausal women. Maturitas. 2007 Feb 20; 56(2):153-60.
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  669. Odink AE, van der Lugt A, Hofman A, Hunink MG, Breteler MM, Krestin GP, Witteman JC. Association between calcification in the coronary arteries, aortic arch and carotid arteries: the Rotterdam study. Atherosclerosis. 2007 Aug; 193(2):408-13.
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  670. de Lau LM, Koudstaal PJ, Hofman A, Breteler MM. Serum cholesterol levels and the risk of Parkinson's disease. Am J Epidemiol. 2006 Nov 15; 164(10):998-1002.
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  671. van den Akker EL, Nouwen JL, Melles DC, van Rossum EF, Koper JW, Uitterlinden AG, Hofman A, Verbrugh HA, Pols HA, Lamberts SW, van Belkum A. Staphylococcus aureus nasal carriage is associated with glucocorticoid receptor gene polymorphisms. J Infect Dis. 2006 Sep 15; 194(6):814-8.
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  672. van Oijen M, Hofman A, Soares HD, Koudstaal PJ, Breteler MM. Plasma Abeta(1-40) and Abeta(1-42) and the risk of dementia: a prospective case-cohort study. Lancet Neurol. 2006 Aug; 5(8):655-60.
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  673. de Voogd S, Ikram MK, Wolfs RC, Jansonius NM, Witteman JC, Hofman A, de Jong PT. Is diabetes mellitus a risk factor for open-angle glaucoma? The Rotterdam Study. Ophthalmology. 2006 Oct; 113(10):1827-31.
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  674. Rietveld I, Ikram MK, Vingerling JR, Hofman A, Pols HA, Lamberts SW, de Jong PT, van Duijn CM, Janssen JA. An igf-I gene polymorphism modifies the risk of diabetic retinopathy. Diabetes. 2006 Aug; 55(8):2387-91.
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  675. Despriet DD, Klaver CC, Witteman JC, Bergen AA, Kardys I, de Maat MP, Boekhoorn SS, Vingerling JR, Hofman A, Oostra BA, Uitterlinden AG, Stijnen T, van Duijn CM, de Jong PT. Complement factor H polymorphism, complement activators, and risk of age-related macular degeneration. JAMA. 2006 Jul 19; 296(3):301-9.
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  676. van Oijen M, de Maat MP, Kardys I, de Jong FJ, Hofman A, Koudstaal PJ, Witteman JC, Breteler MM. Polymorphisms and haplotypes in the C-reactive protein gene and risk of dementia. Neurobiol Aging. 2007 Sep; 28(9):1361-6.
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  677. Jaddoe VW, Mackenbach JP, Moll HA, Steegers EA, Tiemeier H, Verhulst FC, Witteman JC, Hofman A. The Generation R Study: Design and cohort profile. Eur J Epidemiol. 2006; 21(6):475-84.
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  678. Medici M, van Meurs JB, Rivadeneira F, Zhao H, Arp PP, Hofman A, Pols HA, Uitterlinden AG. BMP-2 gene polymorphisms and osteoporosis: the Rotterdam Study. J Bone Miner Res. 2006 Jun; 21(6):845-54.
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  679. Hofman A, de Jong PT, van Duijn CM, Breteler MM. Epidemiology of neurological diseases in elderly people: what did we learn from the Rotterdam Study? Lancet Neurol. 2006 Jun; 5(6):545-50.
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  680. Schelleman H, Klungel OH, Witteman JC, Hofman A, van Duijn CM, de Boer A, Stricker BH. The influence of the alpha-adducin G460W polymorphism and angiotensinogen M235T polymorphism on antihypertensive medication and blood pressure. Eur J Hum Genet. 2006 Jul; 14(7):860-6.
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  681. van Dijk EJ, Prins ND, Hofman A, van Duijn CM, Koudstaal PJ, Breteler MM. Plasma beta amyloid and impaired CO2-induced cerebral vasomotor reactivity. Neurobiol Aging. 2007 May; 28(5):707-12.
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  682. van der Hooft CS, Heeringa J, Brusselle GG, Hofman A, Witteman JC, Kingma JH, Sturkenboom MC, Stricker BH. Corticosteroids and the risk of atrial fibrillation. Arch Intern Med. 2006 May 8; 166(9):1016-20.
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  683. Bos MJ, Koudstaal PJ, Hofman A, Witteman JC, Breteler MM. Uric acid is a risk factor for myocardial infarction and stroke: the Rotterdam study. Stroke. 2006 Jun; 37(6):1503-7.
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  684. Kardys I, Oei HH, Hofman A, Oudkerk M, Witteman JC. Lipoprotein-associated phospholipase A2 and coronary calcification. The Rotterdam Coronary Calcification Study. Atherosclerosis. 2007 Apr; 191(2):377-83.
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  685. Kardys I, de Maat MP, Uitterlinden AG, Hofman A, Witteman JC. C-reactive protein gene haplotypes and risk of coronary heart disease: the Rotterdam Study. Eur Heart J. 2006 Jun; 27(11):1331-7.
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  686. Mantel-Teeuwisse AK, Klungel OH, Hofman A, Verschuren WM, Trienekens PH, Porsius AJ, Stricker BH, de Boer A. Prescribing behaviour according to Dutch and European guidelines on the management of hypercholesterolaemia (1992-1999). Br J Clin Pharmacol. 2006 May; 61(5):592-600.
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  687. van Oijen M, Arp PP, de Jong FJ, Hofman A, Koudstaal PJ, Uitterlinden AG, Breteler MM. Polymorphisms in the interleukin 6 and transforming growth factor beta1 gene and risk of dementia. The Rotterdam Study. Neurosci Lett. 2006 Jul 10; 402(1-2):113-7.
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  688. de Jong FJ, den Heijer T, Visser TJ, de Rijke YB, Drexhage HA, Hofman A, Breteler MM. Thyroid hormones, dementia, and atrophy of the medial temporal lobe. J Clin Endocrinol Metab. 2006 Jul; 91(7):2569-73.
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  689. Kardys I, Klaver CC, Despriet DD, Bergen AA, Uitterlinden AG, Hofman A, Oostra BA, Van Duijn CM, de Jong PT, Witteman JC. A common polymorphism in the complement factor H gene is associated with increased risk of myocardial infarction: the Rotterdam Study. J Am Coll Cardiol. 2006 Apr 18; 47(8):1568-75.
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  690. Yazdanpanah M, Rietveld I, Janssen JA, Njajou OT, Hofman A, Stijnen T, Pols HA, Lamberts SW, Witteman JC, van Duijn CM. An insulin-like growth factor-I promoter polymorphism is associated with increased mortality in subjects with myocardial infarction in an elderly Caucasian population. Am J Cardiol. 2006 May 1; 97(9):1274-6.
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  691. Heeringa J, van der Kuip DA, Hofman A, Kors JA, van Herpen G, Stricker BH, Stijnen T, Lip GY, Witteman JC. Prevalence, incidence and lifetime risk of atrial fibrillation: the Rotterdam study. Eur Heart J. 2006 Apr; 27(8):949-53.
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  692. Nijhuis RL, Stijnen T, Peeters A, Witteman JC, Hofman A, Hunink MG. Apparent and internal validity of a Monte Carlo-Markov model for cardiovascular disease in a cohort follow-up study. Med Decis Making. 2006 Mar-Apr; 26(2):134-44.
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  693. van Popele NM, Elizabeth Hak A, Mattace-Raso FU, Bots ML, van der Kuip DA, Reneman RS, Hoeks AP, Hofman A, Grobbee DE, Witteman JC. Impaired fasting glucose is associated with increased arterial stiffness in elderly people without diabetes mellitus: the Rotterdam Study. J Am Geriatr Soc. 2006 Mar; 54(3):397-404.
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  694. de Torbal A, Boersma E, Kors JA, van Herpen G, Deckers JW, van der Kuip DA, Stricker BH, Hofman A, Witteman JC. Incidence of recognized and unrecognized myocardial infarction in men and women aged 55 and older: the Rotterdam Study. Eur Heart J. 2006 Mar; 27(6):729-36.
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  695. van der Meer IM, Oei HH, Hofman A, Pols HA, de Jong FH, Witteman JC. Soluble Fas, a mediator of apoptosis, C-reactive protein, and coronary and extracoronary atherosclerosis. The Rotterdam Coronary Calcification Study. Atherosclerosis. 2006 Dec; 189(2):464-9.
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  696. Mattace-Raso FU, van der Cammen TJ, Hofman A, van Popele NM, Bos ML, Schalekamp MA, Asmar R, Reneman RS, Hoeks AP, Breteler MM, Witteman JC. Arterial stiffness and risk of coronary heart disease and stroke: the Rotterdam Study. Circulation. 2006 Feb 7; 113(5):657-63.
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  697. Mattace-Raso FU, van der Cammen TJ, Knetsch AM, van den Meiracker AH, Schalekamp MA, Hofman A, Witteman JC. Arterial stiffness as the candidate underlying mechanism for postural blood pressure changes and orthostatic hypotension in older adults: the Rotterdam Study. J Hypertens. 2006 Feb; 24(2):339-44.
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  698. Ikram MK, Janssen JA, Roos AM, Rietveld I, Witteman JC, Breteler MM, Hofman A, van Duijn CM, de Jong PT. Retinal vessel diameters and risk of impaired fasting glucose or diabetes: the Rotterdam study. Diabetes. 2006 Feb; 55(2):506-10.
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  699. Schelleman H, Klungel OH, van Duijn CM, Witteman JC, Hofman A, de Boer A, Stricker BH. Drug-gene interaction between the insertion/deletion polymorphism of the angiotensin-converting enzyme gene and antihypertensive therapy. Ann Pharmacother. 2006 Feb; 40(2):212-8.
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  700. Straus SM, Kors JA, De Bruin ML, van der Hooft CS, Hofman A, Heeringa J, Deckers JW, Kingma JH, Sturkenboom MC, Stricker BH, Witteman JC. Prolonged QTc interval and risk of sudden cardiac death in a population of older adults. J Am Coll Cardiol. 2006 Jan 17; 47(2):362-7.
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  701. de Lau LM, Koudstaal PJ, Hofman A, Breteler MM. Subjective complaints precede Parkinson disease: the rotterdam study. Arch Neurol. 2006 Mar; 63(3):362-5.
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  702. Gumbs PD, Verschuren WM, Mantel-Teeuwisse AK, de Wit AG, Hofman A, Trienekens PH, Stricker BH, de Boer A, Klungel OH. Drug costs associated with non-adherence to cholesterol management guidelines for primary prevention of cardiovascular disease in an elderly population: the Rotterdam study. Drugs Aging. 2006; 23(9):733-41.
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  703. den Heijer T, Geerlings MI, Hoebeek FE, Hofman A, Koudstaal PJ, Breteler MM. Use of hippocampal and amygdalar volumes on magnetic resonance imaging to predict dementia in cognitively intact elderly people. Arch Gen Psychiatry. 2006 Jan; 63(1):57-62.
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  704. van Oijen M, van der Meer IM, Hofman A, Witteman JC, Koudstaal PJ, Breteler MM. Lipoprotein-associated phospholipase A2 is associated with risk of dementia. Ann Neurol. 2006 Jan; 59(1):139-44.
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  705. Söderlund H, Nilsson LG, Berger K, Breteler MM, Dufouil C, Fuhrer R, Giampaoli S, Hofman A, Pajak A, de Ridder M, Sans S, Schmidt R, Launer LJ. Cerebral changes on MRI and cognitive function: the CASCADE study. Neurobiol Aging. 2006 Jan; 27(1):16-23.
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  706. van Leeuwen R, Boekhoorn S, Vingerling JR, Witteman JC, Klaver CC, Hofman A, de Jong PT. Dietary intake of antioxidants and risk of age-related macular degeneration. JAMA. 2005 Dec 28; 294(24):3101-7.
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  707. Ikram MK, Witteman JC, Vingerling JR, Breteler MM, Hofman A, de Jong PT. Retinal vessel diameters and risk of hypertension: the Rotterdam Study. Hypertension. 2006 Feb; 47(2):189-94.
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  708. Kardys I, Oei HH, van der Meer IM, Hofman A, Breteler MM, Witteman JC. Lipoprotein-associated phospholipase A2 and measures of extracoronary atherosclerosis: the Rotterdam Study. Arterioscler Thromb Vasc Biol. 2006 Mar; 26(3):631-6.
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  709. Brugts JJ, Knetsch AM, Mattace-Raso FU, Hofman A, Witteman JC. Renal function and risk of myocardial infarction in an elderly population: the Rotterdam Study. Arch Intern Med. 2005 Dec 12-26; 165(22):2659-65.
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  710. Ikram MK, De Jong FJ, Van Dijk EJ, Prins ND, Hofman A, Breteler MM, De Jong PT. Retinal vessel diameters and cerebral small vessel disease: the Rotterdam Scan Study. Brain. 2006 Jan; 129(Pt 1):182-8.
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  711. van Oijen M, Witteman JC, Hofman A, Koudstaal PJ, Breteler MM. Fibrinogen is associated with an increased risk of Alzheimer disease and vascular dementia. Stroke. 2005 Dec; 36(12):2637-41.
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  712. Sie MP, Sayed-Tabatabaei FA, Oei HH, Uitterlinden AG, Pols HA, Hofman A, van Duijn CM, Witteman JC. Interleukin 6 -174 g/c promoter polymorphism and risk of coronary heart disease: results from the rotterdam study and a meta-analysis. Arterioscler Thromb Vasc Biol. 2006 Jan; 26(1):212-7.
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  713. Mattace-Raso FU, van der Cammen TJ, van den Elzen AP, Schalekamp MA, Asmar R, Reneman RS, Hoeks AP, Hofman A, Witteman JC. Moderate alcohol consumption is associated with reduced arterial stiffness in older adults: the Rotterdam study. J Gerontol A Biol Sci Med Sci. 2005 Nov; 60(11):1479-83.
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  714. de Lau LM, Koudstaal PJ, Hofman A, Breteler MM. Serum uric acid levels and the risk of Parkinson disease. Ann Neurol. 2005 Nov; 58(5):797-800.
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  715. Fang Y, van Meurs JB, d'Alesio A, Jhamai M, Zhao H, Rivadeneira F, Hofman A, van Leeuwen JP, Jehan F, Pols HA, Uitterlinden AG. Promoter and 3'-untranslated-region haplotypes in the vitamin d receptor gene predispose to osteoporotic fracture: the rotterdam study. Am J Hum Genet. 2005 Nov; 77(5):807-23.
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  716. Tiemeier H, Breteler MM, Hofman A, Stijnen T. A multivariate score objectively assessed health of depressed elderly. J Clin Epidemiol. 2005 Nov; 58(11):1134-41.
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  717. van Meurs JB, Rivadeneira F, Jhamai M, Hugens W, Hofman A, van Leeuwen JP, Pols HA, Uitterlinden AG. Common genetic variation of the low-density lipoprotein receptor-related protein 5 and 6 genes determines fracture risk in elderly white men. J Bone Miner Res. 2006 Jan; 21(1):141-50.
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  718. González-Zuloeta Ladd AM, Arias Vásquez A, Sayed-Tabatabaei FA, Coebergh JW, Hofman A, Njajou O, Stricker B, van Duijn C. Angiotensin-converting enzyme gene insertion/deletion polymorphism and breast cancer risk. Cancer Epidemiol Biomarkers Prev. 2005 Sep; 14(9):2143-6.
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  719. Oei HH, Sayed-Tabatabaei FA, Hofman A, Oudkerk M, van Duijn CM, Witteman JC. The association between angiotensin-converting enzyme gene polymorphism and coronary calcification. The Rotterdam Coronary Calcification Study. Atherosclerosis. 2005 Sep; 182(1):169-73.
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  720. de Voogd S, Ikram MK, Wolfs RC, Jansonius NM, Hofman A, de Jong PT. Incidence of open-angle glaucoma in a general elderly population: the Rotterdam Study. Ophthalmology. 2005 Sep; 112(9):1487-93.
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  721. Schuit SC, de Jong FH, Stolk L, Koek WN, van Meurs JB, Schoofs MW, Zillikens MC, Hofman A, van Leeuwen JP, Pols HA, Uitterlinden AG. Estrogen receptor alpha gene polymorphisms are associated with estradiol levels in postmenopausal women. Eur J Endocrinol. 2005 Aug; 153(2):327-34.
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  722. de Lau LM, Schipper CM, Hofman A, Koudstaal PJ, Breteler MM. Prognosis of Parkinson disease: risk of dementia and mortality: the Rotterdam Study. Arch Neurol. 2005 Aug; 62(8):1265-9.
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  723. Vliegenthart R, Oudkerk M, Hofman A, Oei HH, van Dijck W, van Rooij FJ, Witteman JC. Coronary calcification improves cardiovascular risk prediction in the elderly. Circulation. 2005 Jul 26; 112(4):572-7.
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  724. Prins ND, van Dijk EJ, den Heijer T, Vermeer SE, Jolles J, Koudstaal PJ, Hofman A, Breteler MM. Cerebral small-vessel disease and decline in information processing speed, executive function and memory. Brain. 2005 Sep; 128(Pt 9):2034-41.
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  725. Visser LE, van Schaik RH, van Vliet M, Trienekens PH, De Smet PA, Vulto AG, Hofman A, van Duijn CM, Stricker BH. Allelic variants of cytochrome P450 2C9 modify the interaction between nonsteroidal anti-inflammatory drugs and coumarin anticoagulants. Clin Pharmacol Ther. 2005 Jun; 77(6):479-85.
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  726. de Lau LM, Koudstaal PJ, van Meurs JB, Uitterlinden AG, Hofman A, Breteler MM. Methylenetetrahydrofolate reductase C677T genotype and PD. Ann Neurol. 2005 Jun; 57(6):927-30.
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  727. Ruitenberg A, den Heijer T, Bakker SL, van Swieten JC, Koudstaal PJ, Hofman A, Breteler MM. Cerebral hypoperfusion and clinical onset of dementia: the Rotterdam Study. Ann Neurol. 2005 Jun; 57(6):789-94.
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  728. den Heijer T, Hofman A, Koudstaal PJ, Breteler MM. Serum lipids and hippocampal volume: the link to Alzheimer's disease? Ann Neurol. 2005 May; 57(5):779-80; author reply 7780.
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  729. Ikram MK, van Leeuwen R, Vingerling JR, Hofman A, de Jong PT. Retinal vessel diameters and the risk of incident age-related macular disease: the Rotterdam Study. Ophthalmology. 2005 Apr; 112(4):548-52.
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  730. Ikram MK, de Voogd S, Wolfs RC, Hofman A, Breteler MM, Hubbard LD, de Jong PT. Retinal vessel diameters and incident open-angle glaucoma and optic disc changes: the Rotterdam study. Invest Ophthalmol Vis Sci. 2005 Apr; 46(4):1182-7.
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  731. Bots ML, Grobbee DE, Hofman A, Witteman JC. Common carotid intima-media thickness and risk of acute myocardial infarction: the role of lumen diameter. Stroke. 2005 Apr; 36(4):762-7.
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  732. Assink JJ, Klaver CC, Houwing-Duistermaat JJ, Wolfs RC, van Duijn CM, Hofman A, de Jong PT. Heterogeneity of the genetic risk in age-related macular disease: a population-based familial risk study. Ophthalmology. 2005 Mar; 112(3):482-7.
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  733. Oei HH, van der Meer IM, Hofman A, Koudstaal PJ, Stijnen T, Breteler MM, Witteman JC. Lipoprotein-associated phospholipase A2 activity is associated with risk of coronary heart disease and ischemic stroke: the Rotterdam Study. Circulation. 2005 Feb 8; 111(5):570-5.
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  734. Skenduli-Bala E, de Voogd S, Wolfs RC, van Leeuwen R, Ikram MK, Jonas JB, Bakker D, Hofman A, de Jong PT. Causes of incident visual field loss in a general elderly population: the Rotterdam study. Arch Ophthalmol. 2005 Feb; 123(2):233-8.
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  735. Visser LE, Trienekens PH, De Smet PA, Vulto AG, Hofman A, van Duijn CM, Stricker BH. Patients with an ApoE epsilon4 allele require lower doses of coumarin anticoagulants. Pharmacogenet Genomics. 2005 Feb; 15(2):69-74.
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  736. Claassen M, Nouwen J, Fang Y, Ott A, Verbrugh H, Hofman A, van Belkum A, Uitterlinden A. Staphylococcus aureus nasal carriage is not associated with known polymorphism in the Vitamin D receptor gene. FEMS Immunol Med Microbiol. 2005 Feb 1; 43(2):173-6.
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  737. Bleumink GS, Schut AF, Sturkenboom MC, van Duijn CM, Deckers JW, Hofman A, Kingma JH, Witteman JC, Stricker BH. Mortality in patients with hypertension on angiotensin-I converting enzyme (ACE)-inhibitor treatment is influenced by the ACE insertion/deletion polymorphism. Pharmacogenet Genomics. 2005 Feb; 15(2):75-81.
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  738. de Ronde W, Hofman A, Pols HA, de Jong FH. A direct approach to the estimation of the origin of oestrogens and androgens in elderly men by comparison with hormone levels in postmenopausal women. Eur J Endocrinol. 2005 Feb; 152(2):261-8.
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  739. Engelhart MJ, Ruitenberg A, Meijer J, Kiliaan A, van Swieten JC, Hofman A, Witteman JC, Breteler MM. Plasma levels of antioxidants are not associated with Alzheimer's disease or cognitive decline. Dement Geriatr Cogn Disord. 2005; 19(2-3):134-9.
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  740. van der Meer IM, Witteman JC, Hofman A, Kluft C, de Maat MP. Genetic variation in Fcgamma receptor IIa protects against advanced peripheral atherosclerosis. The Rotterdam Study. Thromb Haemost. 2004 Dec; 92(6):1273-6.
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  741. Schut AF, Bleumink GS, Stricker BH, Hofman A, Witteman JC, Pols HA, Deckers JW, Deinum J, van Duijn CM. Angiotensin converting enzyme insertion/deletion polymorphism and the risk of heart failure in hypertensive subjects. Eur Heart J. 2004 Dec; 25(23):2143-8.
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  742. Sleegers K, den Heijer T, van Dijk EJ, Hofman A, Bertoli-Avella AM, Koudstaal PJ, Breteler MM, van Duijn CM. ACE gene is associated with Alzheimer's disease and atrophy of hippocampus and amygdala. Neurobiol Aging. 2005 Aug-Sep; 26(8):1153-9.
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  743. Vliegenthart R, Oei HH, van den Elzen AP, van Rooij FJ, Hofman A, Oudkerk M, Witteman JC. Alcohol consumption and coronary calcification in a general population. Arch Intern Med. 2004 Nov 22; 164(21):2355-60.
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  744. Geleijnse JM, Vermeer C, Grobbee DE, Schurgers LJ, Knapen MH, van der Meer IM, Hofman A, Witteman JC. Dietary intake of menaquinone is associated with a reduced risk of coronary heart disease: the Rotterdam Study. J Nutr. 2004 Nov; 134(11):3100-5.
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  745. van Dijk EJ, Breteler MM, Schmidt R, Berger K, Nilsson LG, Oudkerk M, Pajak A, Sans S, de Ridder M, Dufouil C, Fuhrer R, Giampaoli S, Launer LJ, Hofman A. The association between blood pressure, hypertension, and cerebral white matter lesions: cardiovascular determinants of dementia study. Hypertension. 2004 Nov; 44(5):625-30.
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  746. van den Elzen AP, de Ridder MA, Grobbee DE, Hofman A, Witteman JC, Uiterwaal CS. Families and the natural history of blood pressure. A 27-year follow-up study. Am J Hypertens. 2004 Oct; 17(10):936-40.
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  747. Bleumink GS, Deinum J, Mosterd A, Witteman JC, Hofman A, Stricker BH. Antihypertensive treatment is associated with improved left ventricular geometry: the Rotterdam Study. Pharmacoepidemiol Drug Saf. 2004 Oct; 13(10):703-9.
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  748. den Heijer T, Vermeer SE, van Dijk EJ, Prins ND, Koudstaal PJ, van Duijn CM, Hofman A, Breteler MM. Alcohol intake in relation to brain magnetic resonance imaging findings in older persons without dementia. Am J Clin Nutr. 2004 Oct; 80(4):992-7.
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  749. Prins ND, van Dijk EJ, den Heijer T, Vermeer SE, Koudstaal PJ, Oudkerk M, Hofman A, Breteler MM. Cerebral white matter lesions and the risk of dementia. Arch Neurol. 2004 Oct; 61(10):1531-4.
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  750. Visser LE, Bleumink GS, Trienekens PH, Vulto AG, Hofman A, Stricker BH. The risk of overanticoagulation in patients with heart failure on coumarin anticoagulants. Br J Haematol. 2004 Oct; 127(1):85-9.
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  751. Vokó Z, Hollander M, Koudstaal PJ, Hofman A, Breteler MM. How do American stroke risk functions perform in a Western European population? Neuroepidemiology. 2004 Sep-Oct; 23(5):247-53.
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  752. Bleumink GS, Knetsch AM, Sturkenboom MC, Straus SM, Hofman A, Deckers JW, Witteman JC, Stricker BH. Quantifying the heart failure epidemic: prevalence, incidence rate, lifetime risk and prognosis of heart failure The Rotterdam Study. Eur Heart J. 2004 Sep; 25(18):1614-9.
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  753. Mattace-Raso FU, van der Cammen TJ, van der Meer IM, Schalekamp MA, Asmar R, Hofman A, Witteman JC. C-reactive protein and arterial stiffness in older adults: the Rotterdam Study. Atherosclerosis. 2004 Sep; 176(1):111-6.
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  754. Mattace-Raso FU, van der Cammen TJ, van Popele NM, van der Kuip DA, Schalekamp MA, Hofman A, Breteler MM, Witteman JC. Blood pressure components and cardiovascular events in older adults: the Rotterdam study. J Am Geriatr Soc. 2004 Sep; 52(9):1538-42.
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  755. Nouwen JL, Ott A, Kluytmans-Vandenbergh MF, Boelens HA, Hofman A, van Belkum A, Verbrugh HA. Predicting the Staphylococcus aureus nasal carrier state: derivation and validation of a "culture rule". Clin Infect Dis. 2004 Sep 15; 39(6):806-11.
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  756. Alizadeh BZ, Njajou OT, Houwing-Duistermaat JJ, de Jong G, Vergeer JM, Hofman A, Pols HA, van Duijn CM. Does bilirubin protect against hemochromatosis gene (HFE) related mortality? Am J Med Genet A. 2004 Aug 15; 129A(1):39-43.
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  757. Bleumink GS, Rietveld I, Janssen JA, van Rossum EF, Deckers JW, Hofman A, Witteman JC, van Duijn CM, Stricker BH. Insulin-like growth factor-I gene polymorphism and risk of heart failure (the Rotterdam Study). Am J Cardiol. 2004 Aug 1; 94(3):384-6.
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  758. Maitland-van der Zee AH, Klungel OH, Leufkens HG, de Boer A, Stricker BH, Hofman A, Witteman JC, van Duijn CM, Kastelein JJ. Effectiveness of HMG-CoA reductase inhibitors is modified by the ACE insertion deletion polymorphism. Atherosclerosis. 2004 Aug; 175(2):377-9.
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  759. Oei HH, Vliegenthart R, Deckers JW, Hofman A, Oudkerk M, Witteman JC. The association of Rose questionnaire angina pectoris and coronary calcification in a general population: the Rotterdam Coronary Calcification Study. Ann Epidemiol. 2004 Jul; 14(6):431-6.
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  760. Ikram MK, de Jong FJ, Vingerling JR, Witteman JC, Hofman A, Breteler MM, de Jong PT. Are retinal arteriolar or venular diameters associated with markers for cardiovascular disorders? The Rotterdam Study. Invest Ophthalmol Vis Sci. 2004 Jul; 45(7):2129-34.
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  761. Goderie-Plomp HW, van der Klift M, de Ronde W, Hofman A, de Jong FH, Pols HA. Endogenous sex hormones, sex hormone-binding globulin, and the risk of incident vertebral fractures in elderly men and women: the Rotterdam Study. J Clin Endocrinol Metab. 2004 Jul; 89(7):3261-9.
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  762. Bakker SL, de Leeuw FE, den Heijer T, Koudstaal PJ, Hofman A, Breteler MM. Cerebral haemodynamics in the elderly: the rotterdam study. Neuroepidemiology. 2004 Jul-Aug; 23(4):178-84.
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  763. Visser LE, van Schaik RH, van Vliet M, Trienekens PH, De Smet PA, Vulto AG, Hofman A, van Duijn CM, Stricker BH. The risk of bleeding complications in patients with cytochrome P450 CYP2C9*2 or CYP2C9*3 alleles on acenocoumarol or phenprocoumon. Thromb Haemost. 2004 Jul; 92(1):61-6.
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  764. Schuit SC, Oei HH, Witteman JC, Geurts van Kessel CH, van Meurs JB, Nijhuis RL, van Leeuwen JP, de Jong FH, Zillikens MC, Hofman A, Pols HA, Uitterlinden AG. Estrogen receptor alpha gene polymorphisms and risk of myocardial infarction. JAMA. 2004 Jun 23; 291(24):2969-77.
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  765. Schoofs MW, Sturkenboom MC, van der Klift M, Hofman A, Pols HA, Stricker BH. HMG-CoA reductase inhibitors and the risk of vertebral fracture. J Bone Miner Res. 2004 Sep; 19(9):1525-30.
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  766. Schoofs MW, van der Klift M, Hofman A, van Duijn CM, Stricker BH, Pols HA, Uitterlinden AG. ApoE gene polymorphisms, BMD, and fracture risk in elderly men and women: the Rotterdam study. J Bone Miner Res. 2004 Sep; 19(9):1490-6.
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  767. van Leeuwen R, Tomany SC, Wang JJ, Klein R, Mitchell P, Hofman A, Klein BE, Vingerling JR, Cumming RG, de Jong PT. Is medication use associated with the incidence of early age-related maculopathy? Pooled findings from 3 continents. Ophthalmology. 2004 Jun; 111(6):1169-75.
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  768. van Meurs JB, Dhonukshe-Rutten RA, Pluijm SM, van der Klift M, de Jonge R, Lindemans J, de Groot LC, Hofman A, Witteman JC, van Leeuwen JP, Breteler MM, Lips P, Pols HA, Uitterlinden AG. Homocysteine levels and the risk of osteoporotic fracture. N Engl J Med. 2004 May 13; 350(20):2033-41.
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  769. Croes EA, Alizadeh BZ, Bertoli-Avella AM, Rademaker T, Vergeer-Drop J, Dermaut B, Houwing-Duistermaat JJ, Wientjens DP, Hofman A, Van Broeckhoven C, van Duijn CM. Polymorphisms in the prion protein gene and in the doppel gene increase susceptibility for Creutzfeldt-Jakob disease. Eur J Hum Genet. 2004 May; 12(5):389-94.
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  770. Engelhart MJ, Geerlings MI, Meijer J, Kiliaan A, Ruitenberg A, van Swieten JC, Stijnen T, Hofman A, Witteman JC, Breteler MM. Inflammatory proteins in plasma and the risk of dementia: the rotterdam study. Arch Neurol. 2004 May; 61(5):668-72.
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  771. Mattace-Raso FU, van der Cammen TJ, Sayed-Tabatabaei FA, van Popele NM, Asmar R, Schalekamp MA, Hofman A, van Duijn CM, Witteman JC. Angiotensin-converting enzyme gene polymorphism and common carotid stiffness. The Rotterdam study. Atherosclerosis. 2004 May; 174(1):121-6.
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  772. Rivadeneira F, Houwing-Duistermaat JJ, Beck TJ, Janssen JA, Hofman A, Pols HA, Van Duijn CM, Uitterlinden AG. The influence of an insulin-like growth factor I gene promoter polymorphism on hip bone geometry and the risk of nonvertebral fracture in the elderly: the Rotterdam Study. J Bone Miner Res. 2004 Aug; 19(8):1280-90.
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  773. Bleumink GS, van Duijn CM, Kingma JH, Witteman JC, Hofman A, Stricker BH. Apolipoprotein E epsilon4 allele is associated with left ventricular systolic dysfunction. Am Heart J. 2004 Apr; 147(4):685-9.
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  774. de Leeuw FE, Richard F, de Groot JC, van Duijn CM, Hofman A, Van Gijn J, Breteler MM. Interaction between hypertension, apoE, and cerebral white matter lesions. Stroke. 2004 May; 35(5):1057-60.
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  775. van Dijk EJ, Prins ND, Vermeer SE, Hofman A, van Duijn CM, Koudstaal PJ, Breteler MM. Plasma amyloid beta, apolipoprotein E, lacunar infarcts, and white matter lesions. Ann Neurol. 2004 Apr; 55(4):570-5.
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  776. van Leeuwen R, Klaver CC, Vingerling JR, Hofman A, van Duijn CM, Stricker BH, de Jong PT. Cholesterol and age-related macular degeneration: is there a link? Am J Ophthalmol. 2004 Apr; 137(4):750-2.
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  777. Visser LE, Penning-van Beest FJ, Wilson JH, Vulto AG, Kasbergen AA, De Smet PA, Hofman A, Stricker BH. Overanticoagulation associated with combined use of lactulose and acenocoumarol or phenprocoumon. Br J Clin Pharmacol. 2004 Apr; 57(4):522-4.
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  778. Tiemeier H, van Dijck W, Hofman A, Witteman JC, Stijnen T, Breteler MM. Relationship between atherosclerosis and late-life depression: the Rotterdam Study. Arch Gen Psychiatry. 2004 Apr; 61(4):369-76.
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  779. Schmidt R, Launer LJ, Nilsson LG, Pajak A, Sans S, Berger K, Breteler MM, de Ridder M, Dufouil C, Fuhrer R, Giampaoli S, Hofman A. Magnetic resonance imaging of the brain in diabetes: the Cardiovascular Determinants of Dementia (CASCADE) Study. Diabetes. 2004 Mar; 53(3):687-92.
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  780. van der Meer IM, Bots ML, Hofman A, del Sol AI, van der Kuip DA, Witteman JC. Predictive value of noninvasive measures of atherosclerosis for incident myocardial infarction: the Rotterdam Study. Circulation. 2004 Mar 9; 109(9):1089-94.
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  781. Maitland-van der Zee AH, Klungel OH, Stricker BH, Verschuren WM, Witteman JC, Stijnen T, Hofman A, Breteler MM, Leufkens HG, de Boer A. Comparison of two methodologies to analyze exposure to statins in an observational study on effectiveness. J Clin Epidemiol. 2004 Mar; 57(3):237-42.
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  782. van der Klift M, de Laet CE, McCloskey EV, Johnell O, Kanis JA, Hofman A, Pols HA. Risk factors for incident vertebral fractures in men and women: the Rotterdam Study. J Bone Miner Res. 2004 Jul; 19(7):1172-80.
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  783. van der Meer IM, Brouwers GJ, Bulk S, Leebeek FW, van der Kuip DA, Hofman A, Witteman JC, Gómez García EB. Genetic variability of von Willebrand factor and risk of coronary heart disease: the Rotterdam Study. Br J Haematol. 2004 Feb; 124(3):343-7.
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  784. Schut AF, Sayed-Tabatabaei FA, Witteman JC, Avella AM, Vergeer JM, Pols HA, Hofman A, Deinum J, van Duijn CM. Smoking-dependent effects of the angiotensin-converting enzyme gene insertion/deletion polymorphism on blood pressure. J Hypertens. 2004 Feb; 22(2):313-9.
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  785. Eekhoff ME, van der Klift M, Kroon HM, Cooper C, Hofman A, Pols HA, Papapoulos SE. Paget's disease of bone in The Netherlands: a population-based radiological and biochemical survey--the Rotterdam Study. J Bone Miner Res. 2004 Apr; 19(4):566-70.
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  786. Kors JA, Rijnbeek P, Van Herpen G, Keulers PP, Hofman A, Witteman JC. Spatial repolarization parameters for predicting cardiac death in the elderly. J Electrocardiol. 2004; 37 Suppl:198-200.
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  787. Oei HH, Vliegenthart R, Hofman A, Oudkerk M, Witteman JC. Risk factors for coronary calcification in older subjects. The Rotterdam Coronary Calcification Study. Eur Heart J. 2004 Jan; 25(1):48-55.
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  788. Hofman A, Jaddoe VW, Mackenbach JP, Moll HA, Snijders RF, Steegers EA, Verhulst FC, Witteman JC, Büller HA. Growth, development and health from early fetal life until young adulthood: the Generation R Study. Paediatr Perinat Epidemiol. 2004 Jan; 18(1):61-72.
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  789. Visser LE, van Vliet M, van Schaik RH, Kasbergen AA, De Smet PA, Vulto AG, Hofman A, van Duijn CM, Stricker BH. The risk of overanticoagulation in patients with cytochrome P450 CYP2C9*2 or CYP2C9*3 alleles on acenocoumarol or phenprocoumon. Pharmacogenetics. 2004 Jan; 14(1):27-33.
    View in: PubMed
  790. Schuit SC, van Meurs JB, Bergink AP, van der Klift M, Fang Y, Leusink G, Hofman A, van Leeuwen JP, Uitterlinden AG, Pols HA. Height in pre- and postmenopausal women is influenced by estrogen receptor alpha gene polymorphisms. J Clin Endocrinol Metab. 2004 Jan; 89(1):303-9.
    View in: PubMed
  791. Maitland-van der Zee AH, Klungel OH, Stricker BH, Veenstra DL, Kastelein JJ, Hofman A, Witteman JC, Leufkens HG, van Duijn CM, de Boer A. Pharmacoeconomic evaluation of testing for angiotensin-converting enzyme genotype before starting beta-hydroxy-beta-methylglutaryl coenzyme A reductase inhibitor therapy in men. Pharmacogenetics. 2004 Jan; 14(1):53-60.
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  792. Aulchenko YS, Vaessen N, Heutink P, Pullen J, Snijders PJ, Hofman A, Sandkuijl LA, Houwing-Duistermaat JJ, Edwards M, Bennett S, Oostra BA, van Duijn CM. A genome-wide search for genes involved in type 2 diabetes in a recently genetically isolated population from the Netherlands. Diabetes. 2003 Dec; 52(12):3001-4.
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  793. Bergink AP, van der Klift M, Hofman A, Verhaar JA, van Leeuwen JP, Uitterlinden AG, Pols HA. Osteoarthritis of the knee is associated with vertebral and nonvertebral fractures in the elderly: the Rotterdam Study. Arthritis Rheum. 2003 Oct 15; 49(5):648-57.
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  794. Vliegenthart R, Song B, Hofman A, Witteman JC, Oudkerk M. Coronary calcification at electron-beam CT: effect of section thickness on calcium scoring in vitro and in vivo. Radiology. 2003 Nov; 229(2):520-5.
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  795. Schoofs MW, van der Klift M, Hofman A, de Laet CE, Herings RM, Stijnen T, Pols HA, Stricker BH. Thiazide diuretics and the risk for hip fracture. Ann Intern Med. 2003 Sep 16; 139(6):476-82.
    View in: PubMed
  796. Dekker MC, Giesbergen PC, Njajou OT, van Swieten JC, Hofman A, Breteler MM, van Duijn CM. Mutations in the hemochromatosis gene (HFE), Parkinson's disease and parkinsonism. Neurosci Lett. 2003 Sep 11; 348(2):117-9.
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  797. Fang Y, van Meurs JB, Bergink AP, Hofman A, van Duijn CM, van Leeuwen JP, Pols HA, Uitterlinden AG. Cdx-2 polymorphism in the promoter region of the human vitamin D receptor gene determines susceptibility to fracture in the elderly. J Bone Miner Res. 2003 Sep; 18(9):1632-41.
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  798. Ikram MK, van Leeuwen R, Vingerling JR, Hofman A, de Jong PT. Relationship between refraction and prevalent as well as incident age-related maculopathy: the Rotterdam Study. Invest Ophthalmol Vis Sci. 2003 Sep; 44(9):3778-82.
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  799. van Leeuwen R, Ikram MK, Vingerling JR, Witteman JC, Hofman A, de Jong PT. Blood pressure, atherosclerosis, and the incidence of age-related maculopathy: the Rotterdam Study. Invest Ophthalmol Vis Sci. 2003 Sep; 44(9):3771-7.
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  800. van der Meer IM, Iglesias del Sol A, Hak AE, Bots ML, Hofman A, Witteman JC. Risk factors for progression of atherosclerosis measured at multiple sites in the arterial tree: the Rotterdam Study. Stroke. 2003 Oct; 34(10):2374-9.
    View in: PubMed
  801. Croes EA, Dermaut B, Houwing-Duistermaat JJ, Van den Broeck M, Cruts M, Breteler MM, Hofman A, van Broeckhoven C, van Duijn CM. Early cognitive decline is associated with prion protein codon 129 polymorphism. Ann Neurol. 2003 Aug; 54(2):275-6.
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  802. Tiemeier H, Breteler MM, van Popele NM, Hofman A, Witteman JC. Late-life depression is associated with arterial stiffness: a population-based study. J Am Geriatr Soc. 2003 Aug; 51(8):1105-10.
    View in: PubMed
  803. Rivadeneira F, Houwing-Duistermaat JJ, Vaessen N, Vergeer-Drop JM, Hofman A, Pols HA, Van Duijn CM, Uitterlinden AG. Association between an insulin-like growth factor I gene promoter polymorphism and bone mineral density in the elderly: the Rotterdam Study. J Clin Endocrinol Metab. 2003 Aug; 88(8):3878-84.
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  804. van Meurs JB, Schuit SC, Weel AE, van der Klift M, Bergink AP, Arp PP, Colin EM, Fang Y, Hofman A, van Duijn CM, van Leeuwen JP, Pols HA, Uitterlinden AG. Association of 5' estrogen receptor alpha gene polymorphisms with bone mineral density, vertebral bone area and fracture risk. Hum Mol Genet. 2003 Jul 15; 12(14):1745-54.
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  805. Borger PH, van Leeuwen R, Hulsman CA, Wolfs RC, van der Kuip DA, Hofman A, de Jong PT. Is there a direct association between age-related eye diseases and mortality? The Rotterdam Study. Ophthalmology. 2003 Jul; 110(7):1292-6.
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  806. Tiemeier H, van Tuijl HR, Hofman A, Kiliaan AJ, Breteler MM. Plasma fatty acid composition and depression are associated in the elderly: the Rotterdam Study. Am J Clin Nutr. 2003 Jul; 78(1):40-6.
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  807. Bergink AP, van Meurs JB, Loughlin J, Arp PP, Fang Y, Hofman A, van Leeuwen JP, van Duijn CM, Uitterlinden AG, Pols HA. Estrogen receptor alpha gene haplotype is associated with radiographic osteoarthritis of the knee in elderly men and women. Arthritis Rheum. 2003 Jul; 48(7):1913-22.
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  808. Bosma PJ, van der Meer IM, Bakker CT, Hofman A, Paul-Abrahamse M, Witteman JC. UGT1A1*28 allele and coronary heart disease: the Rotterdam Study. Clin Chem. 2003 Jul; 49(7):1180-1.
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  809. Kardys I, Kors JA, van der Meer IM, Hofman A, van der Kuip DA, Witteman JC. Spatial QRS-T angle predicts cardiac death in a general population. Eur Heart J. 2003 Jul; 24(14):1357-64.
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  810. van der Meer IM, de Maat MP, Kiliaan AJ, van der Kuip DA, Hofman A, Witteman JC. The value of C-reactive protein in cardiovascular risk prediction: the Rotterdam Study. Arch Intern Med. 2003 Jun 9; 163(11):1323-8.
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  811. Geerlings MI, Launer LJ, de Jong FH, Ruitenberg A, Stijnen T, van Swieten JC, Hofman A, Witteman JC, Pols HA, Breteler MM. Endogenous estradiol and risk of dementia in women and men: the Rotterdam Study. Ann Neurol. 2003 May; 53(5):607-15.
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  812. Vermeer SE, Hollander M, van Dijk EJ, Hofman A, Koudstaal PJ, Breteler MM. Silent brain infarcts and white matter lesions increase stroke risk in the general population: the Rotterdam Scan Study. Stroke. 2003 May; 34(5):1126-9.
    View in: PubMed
  813. Maitland-van der Zee AH, Stricker BH, Klungel OH, Mantel-Teeuwisse AK, Kastelein JJ, Hofman A, Leufkens HG, van Duijn CM, de Boer A. Adherence to and dosing of beta-hydroxy-beta-methylglutaryl coenzyme A reductase inhibitors in the general population differs according to apolipoprotein E-genotypes. Pharmacogenetics. 2003 Apr; 13(4):219-23.
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  814. van Leeuwen R, Klaver CC, Vingerling JR, Hofman A, de Jong PT. The risk and natural course of age-related maculopathy: follow-up at 6 1/2 years in the Rotterdam study. Arch Ophthalmol. 2003 Apr; 121(4):519-26.
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  815. Maitland-van der Zee AH, Klungel OH, Stricker BH, van der Kuip DA, Witteman JC, Hofman A, Leufkens HG, de Boer A. Repeated nitrate prescriptions as a potential marker for angina pectoris. A comparison with medical information from the Rotterdam Study. Pharm World Sci. 2003 Apr; 25(2):70-2.
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  816. Vermeer SE, Prins ND, den Heijer T, Hofman A, Koudstaal PJ, Breteler MM. Silent brain infarcts and the risk of dementia and cognitive decline. N Engl J Med. 2003 Mar 27; 348(13):1215-22.
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  817. Dermaut B, Croes EA, Rademakers R, Van den Broeck M, Cruts M, Hofman A, van Duijn CM, Van Broeckhoven C. PRNP Val129 homozygosity increases risk for early-onset Alzheimer's disease. Ann Neurol. 2003 Mar; 53(3):409-12.
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  818. van der Klift M, de Laet CE, Coebergh JW, Hofman A, Pols HA. Bone mineral density and the risk of breast cancer: the Rotterdam Study. Bone. 2003 Mar; 32(3):211-6.
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  819. Heijer Td, Skoog I, Oudkerk M, de Leeuw FE, de Groot JC, Hofman A, Breteler MM. Association between blood pressure levels over time and brain atrophy in the elderly. Neurobiol Aging. 2003 Mar-Apr; 24(2):307-13.
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  820. Njajou OT, Houwing-Duistermaat JJ, Osborne RH, Vaessen N, Vergeer J, Heeringa J, Pols HA, Hofman A, van Duijn CM. A population-based study of the effect of the HFE C282Y and H63D mutations on iron metabolism. Eur J Hum Genet. 2003 Mar; 11(3):225-31.
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  821. Conway DS, Heeringa J, Van Der Kuip DA, Chin BS, Hofman A, Witteman JC, Lip GY. Atrial fibrillation and the prothrombotic state in the elderly: the Rotterdam Study. Stroke. 2003 Feb; 34(2):413-7.
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  822. Vermeer SE, Den Heijer T, Koudstaal PJ, Oudkerk M, Hofman A, Breteler MM. Incidence and risk factors of silent brain infarcts in the population-based Rotterdam Scan Study. Stroke. 2003 Feb; 34(2):392-6.
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  823. Rietveld I, Janssen JA, Hofman A, Pols HA, van Duijn CM, Lamberts SW. A polymorphism in the IGF-I gene influences the age-related decline in circulating total IGF-I levels. Eur J Endocrinol. 2003 Feb; 148(2):171-5.
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  824. den Heijer T, Geerlings MI, Hofman A, de Jong FH, Launer LJ, Pols HA, Breteler MM. Higher estrogen levels are not associated with larger hippocampi and better memory performance. Arch Neurol. 2003 Feb; 60(2):213-20.
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  825. Sijens PE, den Heijer T, Origgi D, Vermeer SE, Breteler MM, Hofman A, Oudkerk M. Brain changes with aging: MR spectroscopy at supraventricular plane shows differences between women and men. Radiology. 2003 Mar; 226(3):889-96.
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  826. Tiemeier H, Hofman A, van Tuijl HR, Kiliaan AJ, Meijer J, Breteler MM. Inflammatory proteins and depression in the elderly. Epidemiology. 2003 Jan; 14(1):103-7.
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  827. Kors JA, Kardys I, van der Meer IM, van Herpen G, Hofman A, van der Kuip DA, Witteman JC. Spatial QRS-T angle as a risk indicator of cardiac death in an elderly population. J Electrocardiol. 2003; 36 Suppl:113-4.
    View in: PubMed
  828. van Leeuwen R, Klaver CC, Vingerling JR, Hofman A, de Jong PT. Epidemiology of age-related maculopathy: a review. Eur J Epidemiol. 2003; 18(9):845-54.
    View in: PubMed
  829. Van Der Meer IM, De Maat MP, Hak AE, Kiliaan AJ, Del Sol AI, Van Der Kuip DA, Nijhuis RL, Hofman A, Witteman JC. C-reactive protein predicts progression of atherosclerosis measured at various sites in the arterial tree: the Rotterdam Study. Stroke. 2002 Dec; 33(12):2750-5.
    View in: PubMed
  830. Hulsman CA, Houwing-Duistermaat JJ, Van Duijn CM, Wolfs R, Borger PH, Hofman A, De Jong PT. Family score as an indicator of genetic risk of primary open-angle glaucoma. Arch Ophthalmol. 2002 Dec; 120(12):1726-31.
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  831. Tiemeier H, van Tuijl HR, Hofman A, Meijer J, Kiliaan AJ, Breteler MM. Vitamin B12, folate, and homocysteine in depression: the Rotterdam Study. Am J Psychiatry. 2002 Dec; 159(12):2099-101.
    View in: PubMed
  832. de Laet CE, van der Klift M, Hofman A, Pols HA. Osteoporosis in men and women: a story about bone mineral density thresholds and hip fracture risk. J Bone Miner Res. 2002 Dec; 17(12):2231-6.
    View in: PubMed
  833. Maitland-van der Zee AH, Stricker BH, Klungel OH, Kastelein JJ, Hofman A, Witteman JC, Breteler MM, Leufkens HG, van Duijn CM, de Boer A. The effectiveness of hydroxy-methylglutaryl coenzyme A reductase inhibitors (statins) in the elderly is not influenced by apolipoprotein E genotype. Pharmacogenetics. 2002 Nov; 12(8):647-53.
    View in: PubMed
  834. Njajou OT, Alizadeh BZ, Vaessen N, Vergeer J, Houwing-Duistermaat J, Hofman A, Pols HA, Van Duijn CM. The role of hemochromatosis C282Y and H63D gene mutations in type 2 diabetes: findings from the Rotterdam Study and meta-analysis. Diabetes Care. 2002 Nov; 25(11):2112-3.
    View in: PubMed
  835. Visser LE, Penning-van Bees FJ, Kasbergen AA, De Smet PA, Vulto AG, Hofman A, Stricker BH. Overanticoagulation associated with combined use of antibacterial drugs and acenocoumarol or phenprocoumon anticoagulants. Thromb Haemost. 2002 Nov; 88(5):705-10.
    View in: PubMed
  836. Tiemeier H, Hofman A, Kiliaan AJ, Meijer J, Breteler MM. Vitamin E and depressive symptoms are not related. The Rotterdam Study. J Affect Disord. 2002 Oct; 72(1):79-83.
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  837. Njajou OT, Hollander M, Koudstaal PJ, Hofman A, Witteman JC, Breteler MM, van Duijn CM. Mutations in the hemochromatosis gene (HFE) and stroke. Stroke. 2002 Oct; 33(10):2363-6.
    View in: PubMed
  838. De Groot JC, De Leeuw FE, Oudkerk M, Van Gijn J, Hofman A, Jolles J, Breteler MM. Periventricular cerebral white matter lesions predict rate of cognitive decline. Ann Neurol. 2002 Sep; 52(3):335-41.
    View in: PubMed
  839. Hak AE, Witteman JC, de Jong FH, Geerlings MI, Hofman A, Pols HA. Low levels of endogenous androgens increase the risk of atherosclerosis in elderly men: the Rotterdam study. J Clin Endocrinol Metab. 2002 Aug; 87(8):3632-9.
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  840. Jaquet JB, Kalmijn S, Kuypers PD, Hofman A, Passchier J, Hovius SE. Early psychological stress after forearm nerve injuries: a predictor for long-term functional outcome and return to productivity. Ann Plast Surg. 2002 Jul; 49(1):82-90.
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  841. Engelhart MJ, Geerlings MI, Ruitenberg A, van Swieten JC, Hofman A, Witteman JC, Breteler MM. Dietary intake of antioxidants and risk of Alzheimer disease. JAMA. 2002 Jun 26; 287(24):3223-9.
    View in: PubMed
  842. Oei HH, Vliegenthart R, Hak AE, Iglesias del Sol A, Hofman A, Oudkerk M, Witteman JC. The association between coronary calcification assessed by electron beam computed tomography and measures of extracoronary atherosclerosis: the Rotterdam Coronary Calcification Study. J Am Coll Cardiol. 2002 Jun 5; 39(11):1745-51.
    View in: PubMed
  843. Van der Klift M, De Laet CE, McCloskey EV, Hofman A, Pols HA. The incidence of vertebral fractures in men and women: the Rotterdam Study. J Bone Miner Res. 2002 Jun; 17(6):1051-6.
    View in: PubMed
  844. Visser LE, Penning-van Beest FJ, Kasbergen AA, De Smet PA, Vulto AG, Hofman A, Stricker BH. Overanticoagulation associated with combined use of antifungal agents and coumarin anticoagulants. Clin Pharmacol Ther. 2002 Jun; 71(6):496-502.
    View in: PubMed
  845. Geleijnse JM, Launer LJ, Van der Kuip DA, Hofman A, Witteman JC. Inverse association of tea and flavonoid intakes with incident myocardial infarction: the Rotterdam Study. Am J Clin Nutr. 2002 May; 75(5):880-6.
    View in: PubMed
  846. van der Meer IM, de Maat MP, Bots ML, Breteler MM, Meijer J, Kiliaan AJ, Hofman A, Witteman JC. Inflammatory mediators and cell adhesion molecules as indicators of severity of atherosclerosis: the Rotterdam Study. Arterioscler Thromb Vasc Biol. 2002 May 1; 22(5):838-42.
    View in: PubMed
  847. Hulsman CA, De Jong PT, Lettink M, Van Duijn CM, Hofman A, Bergen AA. Myocilin mutations in a population-based sample of cases with open-angle glaucoma: the Rotterdam Study. Graefes Arch Clin Exp Ophthalmol. 2002 Jun; 240(6):468-74.
    View in: PubMed
  848. Vaessen N, Janssen JA, Heutink P, Hofman A, Lamberts SW, Oostra BA, Pols HA, van Duijn CM. Association between genetic variation in the gene for insulin-like growth factor-I and low birthweight. Lancet. 2002 Mar 23; 359(9311):1036-7.
    View in: PubMed
  849. Ikram MK, Borger PH, Assink JJ, Jonas JB, Hofman A, de Jong PT. Comparing ophthalmoscopy, slide viewing, and semiautomated systems in optic disc morphometry. Ophthalmology. 2002 Mar; 109(3):486-93.
    View in: PubMed
  850. Vermeer SE, van Dijk EJ, Koudstaal PJ, Oudkerk M, Hofman A, Clarke R, Breteler MM. Homocysteine, silent brain infarcts, and white matter lesions: The Rotterdam Scan Study. Ann Neurol. 2002 Mar; 51(3):285-9.
    View in: PubMed
  851. Vliegenthart R, Geleijnse JM, Hofman A, Meijer WT, van Rooij FJ, Grobbee DE, Witteman JC. Alcohol consumption and risk of peripheral arterial disease: the Rotterdam study. Am J Epidemiol. 2002 Feb 15; 155(4):332-8.
    View in: PubMed
  852. Vliegenthart R, Hollander M, Breteler MM, van der Kuip DA, Hofman A, Oudkerk M, Witteman JC. Stroke is associated with coronary calcification as detected by electron-beam CT: the Rotterdam Coronary Calcification Study. Stroke. 2002 Feb; 33(2):462-5.
    View in: PubMed
  853. Ruitenberg A, van Swieten JC, Witteman JC, Mehta KM, van Duijn CM, Hofman A, Breteler MM. Alcohol consumption and risk of dementia: the Rotterdam Study. Lancet. 2002 Jan 26; 359(9303):281-6.
    View in: PubMed
  854. Vermeer SE, Koudstaal PJ, Oudkerk M, Hofman A, Breteler MM. Prevalence and risk factors of silent brain infarcts in the population-based Rotterdam Scan Study. Stroke. 2002 Jan; 33(1):21-5.
    View in: PubMed
  855. Meijer WT, Grobbee DE, Hunink MG, Hofman A, Hoes AW. Determinants of peripheral arterial disease in the elderly: the Rotterdam study. Arch Intern Med. 2000 Oct 23; 160(19):2934-8.
    View in: PubMed
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