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Kirby Vosburgh, PH.D.

TitleAssistant Professor of Radiology
InstitutionBrigham and Women's Hospital
DepartmentRadiology
AddressBrigham and Womens Hospital
Radiology, L1-050
75 Francis St
Boston MA 02115
Phone617/525-3031

 Biography 
 awards and honors
1961 - 1965John McMullen Scholar
1997 - Whitney Technical Acheivement Award
2006 - Edward M. Kennedy Award for Healthcare Innovation
2011 - Richard Satava Award

 Overview 
 overview
Kirby Vosburgh is a physicist interested in seeing newly developed technologies become effective in clinical practice. Since coming to CIMIT and HMS in 2000, he has applied his mentoring and leadership skills to create high tech solutions to clinical problems by supporting teams of physicians and engineers.

Background/Experience:

o BS, MS Engineering Physics, (Cornell), PhD (Rutgers) in Applied Physics and Physics; Post-doc at Princeton in Physics. Many years ago.
o GE R&D 1972-2000. Senior Executive; managed large scale laboratories which developed many products, including medical imaging systems.
o CIMIT (Center for Integration of Medicine and Innovative Technology) 2000-2010, Associate Director. Last 5 years as Director of science peer review, project selection and management.
o In 2011, he received the Satava Award for his contributions to Virtual Reality in Medicine

Current Positions (Brigham and Women’s Hospital):

o Lead research teams to increase the clinical impact of image guided approaches. Support and mentor early career investigators.
o Assistant Professor of Radiology, Harvard; full time 10/2010
o Dr. Vosburgh also serves as Associate Director, Advanced Multimodality Image Guidance Operating Room (AMIGO)
o Research Scientist, Massachusetts General Hospital

Current Work:

Dr. Vosburgh’s laboratory brings virtual reality approaches to benefit interventional clinicians: surgeons, gastroenterologists, and urologists. His team provides “GPS for the abdomen” while not requiring complex radiologic equipment in their procedure or operating rooms. To this end, he has participated in over 20 porcine model surgeries and 25 tests in humans as well as being the Principal Investigator responsible for the scientific direction and administrative processes for these studies. A key contribution of his laboratory has been the development of kinematics-based metrics for operator performance. These have been applied to laparoscopic, endoscopic, and urologic surgery, and most recently to performance characterization in diagnostic examinations such as colonoscopy. My laboratory is focused on demonstrating that high tech approaches to interventions provide more effective and efficacious solutions to acute clinical challenges. See www.ciglab.org.

In 2000, he completed a 28 year career as an industrial R+D manager, reaching the Senior Executive Band of GE. As the manager of several GE laboratories, he lead the development of advanced IC process technology, electronic materials and components, lighting systems, software technology, and large scale electronic systems, including MR imaging, ultrasound, and related technologies.

Building on this background, Dr. Vosburgh expects that his work creating new clinical capabilities and mentoring multidisciplinary teams at HMS will be the most significant of his career.


 Bibliographic 
 selected publications
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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  1. Córdova H, San José Estépar R, Rodríguez-D'Jesús A, Martínez-Pallí G, Arguis P, Rodríguez de Miguel C, Navarro-Ripoll R, Perdomo JM, Cuatrecasas M, Llach J, Vosburgh KG, Fernández-Esparrach G. Comparative study of NOTES alone versus NOTES guided by a new image registration system for navigation in the mediastinum: a study in a porcine model. Gastrointest Endosc. 2013 Jan; 77(1):102-7.
    View in: PubMed
  2. Azagury DE, Ryou M, Shaikh SN, San José Estépar R, Lengyel BI, Jagadeesan J, Vosburgh KG, Thompson CC. Real-time computed tomography-based augmented reality for natural orifice transluminal endoscopic surgery navigation. Br J Surg. 2012 Sep; 99(9):1246-53.
    View in: PubMed
  3. Park SY, Sargent D, Spofford I, Vosburgh KG, A-Rahim Y. A colon video analysis framework for polyp detection. IEEE Trans Biomed Eng. 2012 May; 59(5):1408-18.
    View in: PubMed
  4. Linte CA, Davenport KP, Cleary K, Peters C, Vosburgh KG, Edwards P, Jannin P, Peters TM, Holmes Iii DR, Robb RA. Augmented environments for minimally invasive therapy: implementation barriers from technology to practice. Stud Health Technol Inform. 2012; 173:263-9.
    View in: PubMed
  5. Obstein KL, Estépar RS, Jayender J, Patil VD, Spofford IS, Ryan MB, Lengyel BI, Shams R, Vosburgh KG, Thompson CC. Image Registered Gastroscopic Ultrasound (IRGUS) in human subjects: a pilot study to assess feasibility. Endoscopy. 2011 May; 43(5):394-9.
    View in: PubMed
  6. Obstein KL, Patil VD, Jayender J, San José Estépar R, Spofford IS, Lengyel BI, Vosburgh KG, Thompson CC. Evaluation of colonoscopy technical skill levels by use of an objective kinematic-based system. Gastrointest Endosc. 2011 Feb; 73(2):315-21, 321.e1.
    View in: PubMed
  7. Fernández-Esparrach G, San José Estépar R, Guarner-Argente C, Martínez-Pallí G, Navarro R, Rodríguez de Miguel C, Córdova H, Thompson CC, Lacy AM, Donoso L, Ayuso-Colella JR, Ginès A, Pellisé M, Llach J, Vosburgh KG. The role of a computed tomography-based image registered navigation system for natural orifice transluminal endoscopic surgery: a comparative study in a porcine model. Endoscopy. 2010 Dec; 42(12):1096-103.
    View in: PubMed
  8. San Jose Estepar, R, B. Madore, M Yarmarkovich, KG Vosburgh. An MRI study of relative organ position in the upper abdomen for changes in patient orientation: application to image registered endoscopic ultrasound. 2009.
  9. Patil, V, R. San Jose Estepar, CJ Walsh, KG Vosburgh. Dynamic CT environment effect on a DC electromagnetic tracking system. 2009.
  10. San José Estépar R, Westin CF, Vosburgh KG. Towards real time 2D to 3D registration for ultrasound-guided endoscopic and laparoscopic procedures. Int J Comput Assist Radiol Surg. 2009 Nov; 4(6):549-60.
    View in: PubMed
  11. Fernández-Esparrach, MG, R. San José Estepar, F. P. Martins, M. Yarmakovich, C. C. Thompson, K.G. Vosburgh. EUS with CT improves structure identification in the mediastinum of a porcine model. Gut. 2008; 57:A300.
  12. Vosburgh KG, Stoll J, Noble V, Pohl K, San José Estepar R, Takacs B. Image registration assists novice operators in ultrasound assessment of abdominal trauma. Stud Health Technol Inform. 2008; 132:532-7.
    View in: PubMed
  13. Estépar RS, Stylopoulos N, Ellis R, Samset E, Westin CF, Thompson C, Vosburgh K. Towards scarless surgery: an endoscopic ultrasound navigation system for transgastric access procedures. Comput Aided Surg. 2007 Nov; 12(6):311-24.
    View in: PubMed
  14. Velmahos GC, Spaniolas K, Duggan M, Alam HB, Tabbara M, de Moya M, Vosburgh K. Abdominal insufflation for control of bleeding after severe splenic injury. J Trauma. 2007 Aug; 63(2):285-8; discussion 288-90.
    View in: PubMed
  15. Stylopoulos N, Vosburgh KG. Assessing technical skill in surgery and endoscopy: a set of metrics and an algorithm (C-PASS) to assess skills in surgical and endoscopic procedures. Surg Innov. 2007 Jun; 14(2):113-21.
    View in: PubMed
  16. Krissian K, Westin CF, Kikinis R, Vosburgh KG. Oriented speckle reducing anisotropic diffusion. IEEE Trans Image Process. 2007 May; 16(5):1412-24.
    View in: PubMed
  17. Vosburgh KG, Stylopoulos N, Estepar RS, Ellis RE, Samset E, Thompson CC. EUS with CT improves efficiency and structure identification over conventional EUS. Gastrointest Endosc. 2007 May; 65(6):866-70.
    View in: PubMed
  18. Dimaio S, Kapur T, Cleary K, Aylward S, Kazanzides P, Vosburgh K, Ellis R, Duncan J, Farahani K, Lemke H, Peters T, Lorensen WB, Gobbi D, Haller J, Clarke LL, Pizer S, Taylor R, Galloway R, Fichtinger G, Hata N, Lawson K, Tempany C, Kikinis R, Jolesz F. Challenges in image-guided therapy system design. Neuroimage. 2007; 37 Suppl 1:S144-51.
    View in: PubMed
  19. Vosburgh KG, San José Estépar R. Natural Orifice Transluminal Endoscopic Surgery (NOTES): an opportunity for augmented reality guidance. Stud Health Technol Inform. 2007; 125:485-90.
    View in: PubMed
  20. Vosburgh, Kirby G., Nicholas Stylopoulos, Christopher C. Thompson, Randy Ellis, Eigil Samset, Raul San Jose Estepar. "Novel Real Time Tracking Interface Improves the Use of Laparoscopic and Endoscopic Ultrasound in the Abdomen.". Int J Comput Assis Radiol Surg. 2006; 1(S1):282-284.
  21. Vosburgh, KG. "Bioimaging in Neurodegeneration" - Book review. Epilepsy and Behavior. 2006.
  22. Pai, R.; Fong, D.; Fishman, D.; Sylopoulos, N.; Rattner, D.; Vosburgh, K.; Thompson, C. "Endoscopic Transcolonic Colecystectomy in a Porcine Model.". 2006.
  23. Thompson, C.C., Nicholas Stylopoulos, R. San Jose Estepar, E. Samset, R. Ellis, W. Brugge, K.G. Vosburgh. "Image Registered Gastroscopic Ultrasound (IRGUS): 3D Registration of Endoscopic Ultrasound and CT Improves Efficiency and Structure Identification over Standard Endoscopic Ultrasound". Digestive Disease Week 2006. 2006.
  24. Pai R., Fong D., Fishman D., Stylopoulos N., Rattner D., Vosburgh K. "Endoscopic Transcolonic Colesystectomy in a Porcine Model". Digestive Disease Week-2006 ASGE Video Forum. 2006.
  25. Vosburgh, Kirby G., Randy Ellis. "Tracking Instruments and Probes in the Body: Current and Future Opportunities". MMVR 2006. 2006.
  26. Vosburgh, KG; N Stylopoulos; R San Jose Estepar; RE Ellis; E Samset; CC Thompson . EUS and CT Improves Efficiency and Structure Identification over Conventional EUS. Gastrointestinal Endoscopy (in press). 2006.
  27. San José Estépar R, Stylopoulos N, Ellis RE, Samset E, Westin CF, Thompson C, Vosburgh K. Towards scarless surgery: an endoscopic-ultrasound navigation system for transgastric access procedures. Med Image Comput Comput Assist Interv. 2006; 9(Pt 1):445-53.
    View in: PubMed
  28. Bricault, Ivan, S. DiMaio, O. Clatz, S. Pujol, K. Vosburgh, R. Kikinis. "Computer-Assisted Interventions on liver: Feasibility of the anchor needle technique for real-time targeting of lesions with respiratory motion.". Surgetica. 2005.
  29. Vosburgh KG. Beyond VR: creating the augmented physician. Stud Health Technol Inform. 2005; 111:574-8.
    View in: PubMed
  30. Vosburgh, KG. Image Guided Surgery: Recent Trends. Medicine Meets Virtual Reality 2005. 2005.
  31. Ellsmere J, Stoll J, Wells W, Kikinis R, Vosburgh K, Kane R, Brooks D, Rattner D. A new visualization technique for laparoscopic ultrasonography. Surgery. 2004 Jul; 136(1):84-92.
    View in: PubMed
  32. Bush, SF, JE Hershey, KG Vosburgh, BE Osborn. Apparatus and method for analyzing the brittleness of a system. 2004.
  33. Vosburgh, KG, N. Stylopoulos, S. Pujol, R. San Jose Estepar, K. Krissian, I. Bricault, J. Ellsmere. Guiding Abdominal Surgery with Image Registered Laparoscopic Ultrasound (IRLUS). Proc. Radiologic Society of North America (RSNA) . 2004.
  34. Ross, JA Fergus, KG Vosburgh, JJ Tiemann, KH Valborg Hedengren. Internet related appliances. 2003.
  35. Vosburgh KG, Jolesz FA. The concept of image-guided therapy. Acad Radiol. 2003 Feb; 10(2):176-9.
    View in: PubMed
  36. Vosburgh, KG. New Sensor Developments and Clinical Practice. Medicien Meet Virtual Reality 11 (2003). 2003.
  37. Ellsmere, J., Stoll JA, Rattner DW, Brooks D, Kane, R, Wells WM III, Kikinis R, Vosburgh KG. . Integrating preoperative CT data with laparoscopic ultrasound images facilitates interpretation. Proceedings of the Society of American Gastrointestinal Endoscopic Surgeons. 2003.
  38. Krissian, K., J. Ellsmere, K. Vosburgh, R. Kikinis, and C.-F. Westin. "Multiscale Segmentation of the Aorta in 3D Ultrasound Images". 25th Annual Int. Conf. of the Institute of Electrical and Electronics Engineers (IEEE)Engineering in Medicine and Biology (EMBS). 2003; 638-641.
  39. Ellsmere, J., J. Stoll, D. Rattner, D. Brooks, R. Kane, W. Wells, R. Kikinis, K. Vosburgh. A Navigation System for Augmenting Laparoscopic Ultrasound. Lecture Notes in Computer Science. 2003; (2879):184-191.
  40. Ellsmere, J., Stoll JA, Rattner DW, Brooks D, Kane R, Wells WM III, Kikinis R, Vosburgh KG. "Integrating preoperative CT data with laparoscopic ultrasound images facilitates interpretation". Soc. Amer. Gastrointestinal Endoscopic Surgeons (SAGES). 2003.
  41. Vosburgh KG, Newbower RS. Moore's Law, disruptive technologies, and the clinician. Stud Health Technol Inform. 2002; 85:8-13.
    View in: PubMed
  42. Vosburgh, KG. The Operating Room of the Future. Medicine Meets Virtual Reality 2002. 2002.
  43. Vosburgh, KG. Planning the Operating Room of the Future. Medicine Meets Virtual Reality 2001. 2001.
  44. Higgins G, Athey B, Bassingthwaighte J, Burgess J, Champion H, Cleary K, Dev P, Duncan J, Hopmeier M, Jenkins D, Johnson C, Kelly H, Leitch R, Lorensen W, Metaxas D, Spitzer V, Vaidehi N, Vosburgh K, Winslow R. Final report of the meeting "modeling & simulation in medicine: towards an integrated framework". July 20-21, 2000, National Library of Medicine, National Institutes of Health, Bethesda, Maryland, USA. Comput Aided Surg. 2001; 6(1):32-9.
    View in: PubMed
  45. Carl AL, Khanuja HS, Gatto CA, Matsumoto M, vomLehn J, Schenck J, Rohling K, Lorensen W, Vosburgh K. In vivo pedicle screw placement: image-guided virtual vision. J Spinal Disord. 2000 Jun; 13(3):225-9.
    View in: PubMed
  46. Vosburgh, KG. Improving Care And Caring – How Technology will Enhance the Physician/Patient Relationship. Medicine Meets Virtual Reality 2000. 2000.
  47. Carl, A.L. H.S. Khanuja, C.A. Gatto, J.C. vom Lehn, K. G. Vosburgh, J. D. Schenck, W.E. Lorensen, K. Rohling. Early Experience: Computer-Assisted Navigation and Pedicle Screw Placement. Revision Spine Surgery (Margulies, Aebi, & Farcy, Eds),. 1999.
  48. Zerhouni EA, Plewes D, Vosburgh KG. National Cancer Institute partnerships with Academia and Industry in Cancer Diagnosis and Treatment: report of the workshop. Acad Radiol. 1998 Feb; 5(2):133-40.
    View in: PubMed
  49. Vosburgh KG, Schenck JF. Experience with MR-guided therapy. Stud Health Technol Inform. 1998; 50:144-9.
    View in: PubMed
  50. Carl AL, Khanuja HS, Sachs BL, Gatto CA, vomLehn J, Vosburgh K, Schenck J, Lorensen W, Rohling K, Disler D. In vitro simulation. Early results of stereotaxy for pedicle screw placement. Spine (Phila Pa 1976). 1997 May 15; 22(10):1160-4.
    View in: PubMed
  51. Vosburgh, KG. Image Guided Surgery and its Potential. Medicine Meets Virtual Reality-Global Healthcare Grid. 1997; 39:83-89.
  52. Vosburgh KG. Image guided surgery and its potential. Stud Health Technol Inform. 1997; 39:83-9.
    View in: PubMed
  53. Uzgiris, E.E., L.R. Opsahl, K.G. Vosburgh, T.R. Anthony, H.E. Cline. Targeted Thermal Release of Drug-Polymer Conjugates. 1996.
  54. Roemer, P.B., S.M. Blumenfeld, K.G. Vosburgh, H.E. Cline, W. D. Barber, W.E. Lorensen, R.L. St. Peters, J.F. Schenck, C.L. Dumoulin, R.D. Darrow, CJ. Hardy, . Magnetic Resonance Imaging System with Pointing Device. 1994.
  55. Vosburgh, K.G. Facilities for VLSI Circuit Fabrication. VLSI Handbook, N. Einspruch, Ed. 1985; 7.
  56. Brown, D.M., K.G. Vosburgh. Method of Making Integrated Circuits. 1983.
  57. Vosburgh, K.G., . Compressed Air Energy Storage. J. Energy. 1978; 2:106.
  58. McNulty, P.J., V. P. Pease, V. P. Bond, W. Schimmerling, K.G. Vosburgh, K. Crebbin, W. Everette, J. Howard. Delivery of Single Accelerated Particles. Nuclear Instruments and Methods. 1978; 155:325.
  59. Schimmerling W, Curtis SB, Vosburgh KG. Velocity spectrometry of 3.5-GeV nitrogen ions. Radiat Res. 1977 Oct; 72(1):1-17.
    View in: PubMed
  60. Vosburgh KG, Glascock HH. Two systems for direct radiographic miniaturization. IEEE Trans Biomed Eng. 1977 Jul; 24(4):353-61.
    View in: PubMed
  61. Vosburgh KG. Storage and retrieval of radiographic images. Radiology. 1977 Jun; 123(3):619-24.
    View in: PubMed
  62. McNulty, P.J., G. E. Farrell, R. C. Filz, W. Schimmerling, K.G. Vosburgh, . Threshold Pion Production and Multiplicity in Heavy-Ion Collisions. Physical Review Letters. 1977; 38:1519.
  63. Vosburgh, KG., R.K. Swank, J.M. Houston . X-ray Image Intensifiers. Advances in Electronics and Electron Physics. 1977; 43:205.
  64. Vosburgh, KG. Improved X-ray Image Intensifier. 1976.
  65. Schimmerling W, Vosburgh KG, Appleby A, Todd PW. Apparatus and dosimetry for high-energy heavy-ion-beam irradiations. Radiat Res. 1976 Mar; 65(3):389-413.
    View in: PubMed
  66. Vosburgh, K.G., J.F. Schenck. Solid State Surface Change Sensor. Rev. Sci. Instruments. 1976; 47:972.
  67. Cleland, W.E., B. Goz, D. Freytag, T. J. Devlin, R. J. Esterling, K.G. Vosburgh, . Measurement of the KL0-p and KL0-d Total Cross Sections. Physical Review. 1975; D12:1247.
  68. Vosburgh, KG, W. Schimmerling, K. Koepke, W. D. Wales, . Measurement of Charged Pion Production by 7.28 GeV Nitrogen Ions. Physical Review. 1975; D11:1743.
  69. Schimmerling, W., K.G. Vosburgh, W., K. Koepke, W. D. Wales. Measurement of Charged-Pion Production by 7.28 GeV Nitrogen Ions. Physical Review Letters. 1974; 33:1170.
  70. Devlin, T.J., W. Johnson, J. Norem, K.G. Vosburgh, R. E. Mischke, W. Schimmerling. Measurement of n-p and n-d Total Cross Sections from 0.7 to 3.6 GeV/c. Physical Review. 1973; D8:136.
  71. Schimmerling, W., K.G. Vosburgh, P.W. Todd. Measurements of Range in Matter of Relativistic Heavy Ions. Physical Review. 1973; B7:2895.
  72. Vosburgh, K.G. Radioterapia del cancro con ioni pesanti, ("Radiation Cancer Therapy with Heavy Ion Beams"). Enciclopedia della Scienza e della Tecnica. 1973.
  73. Schimmerling, W., T. J. Devlin, W. Johnson, K.G. Vosburgh, R.E. Mischke, . Neutron-Nucleus Total and Inelastic Cross Sections: 900 to 2600 MeV/c. Physical Review. 1973; C7:248.
  74. Todd P, Schroy CB, Schimmerling W, Vosburgh KG. Cellular effects of heavy charged particles. Life Sci Space Res. 1973; 11:261-70.
    View in: PubMed
  75. McNulty PJ, Pease VP, Pinsky LS, Bond VP, Schimmerling W, Vosburgh KG. Visual sensations induced by relativistic nitrogen nuclei. Science. 1972 Oct 13; 178(4057):160-2.
    View in: PubMed
  76. Isaila MV, Schimmerling W, Vosburgh KG, White MG, Filz RC, McNulty PJ. Acceleration of argon ions to 1.17x1010 electron volts. Science. 1972 Aug 4; 177(4047):424-5.
    View in: PubMed
  77. Vosburgh, K.G., T. J. Devlin, R. J. Esterling, B. Goz, D. A. Bryman, W.E. Cleland. Measurement of the KL0 Mean Life. Physical Review. 1972; D6:1834.
  78. Vosburgh KG. Prediction of the spatial distribution of cell survival in heavy ion beams. Science. 1971 Dec 10; 174(4014):1125-7.
    View in: PubMed
  79. Schimmerling W, Vosburgh KG, Todd PW. Interaction of 3.9-gev nitrogen ions with matter. Science. 1971 Dec 10; 174(4014):1123-5.
    View in: PubMed
  80. Todd P, Schroy CB, Vosburgh KG, Schimmerling W. Spatial distribution of biological effect n a 3.9-Gev nitrogen ion beam. Science. 1971 Dec 10; 174(4014):1127-8.
    View in: PubMed
  81. Schimmerling, W., T. J. Devlin, W. Johnson, K.G. Vosburgh, R. E. Mischke. Neutron-Nucleus Total Cross Sections from 900 to 2600 MeV/c. Physics Letters. 1971; 37B:177.
  82. Vosburgh, KG. A Measurement of the KL0 Mean Life. 1971.
  83. Vosburgh, K.G., T. J. Devlin, R. J. Esterling, B. Goz, D. A. Bryman, W.E. Cleland. Measurement of the KL0 Mean Life. Physical Review Letters. 1971; 26:866.
  84. Mischke, R.E., T. J. Devlin, W. Johnson, J. Norem, K.G. Vosburgh, W. Schimmerling. Direct Measurement of n-p and n-d Total Cross Sections from 700 to 2900 MeV/c. Physical Review Letters. 1970; 25:174.
  85. Kawakatsu, H., K.G. Vosburgh, B.M. Siegel. Electron-Optical Properties of a Quadrupole Quadruplet Projector Lens. J. Applied Physics. 1968; 39:245-254.
  86. Kawakatsu, H., K.G. Vosburgh, B.M. Siegel . Mechanical Aberrations of a Magnetic Quadrupole Quadruplet Lens. J. Applied Physics. 1968; 39:255-260.
  87. Vosburgh, KG. The Aberrations of a Quadrupole Quadruplet Projector. 1967.
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