 Marianne Amanda Grant, PH.D.
| Title | Instructor in Medicine |
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| Institution | Beth Israel Deaconess Medical Center |
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| Department | Medicine |
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| Address | Beth Israel Deaconess Med Ctr
RN 270E, Molecular & Vascular Med
330 Brookline Ave
Boston MA 02215
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| Phone | 617/667-2865 |
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| Fax | 617/667-2913 |
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 Bibliographic
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications.
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Grant, MA, Aird, WC
. Hemostasis and Thrombosis. Evolution of the Vertebrate Colagulation Cascade. 2012.
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Segal MS, Sautina L, Li S, Diao Y, Agoulnik AI, Kielczewski J, McGuane JT, Grant MB, Conrad KP. Relaxin increases human endothelial progenitor cell NO and migration and vasculogenesis in mice. Blood. 2012 Jan 12; 119(2):629-36.
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Cai J, Chen Z, Ruan Q, Han S, Liu L, Qi X, Boye SL, Hauswirth WW, Grant MB, Boulton ME. ?-Secretase and presenilin mediate cleavage and phosphorylation of vascular endothelial growth factor receptor-1. J Biol Chem. 2011 Dec 9; 286(49):42514-23.
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McGuane JT, Debrah JE, Sautina L, Jarajapu YP, Novak J, Rubin JP, Grant MB, Segal M, Conrad KP. Relaxin induces rapid dilation of rodent small renal and human subcutaneous arteries via PI3 kinase and nitric oxide. Endocrinology. 2011 Jul; 152(7):2786-96.
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Cai J, Wu L, Qi X, Shaw L, Li Calzi S, Caballero S, Jiang WG, Vinores SA, Antonetti D, Ahmed A, Grant MB, Boulton ME. Placenta growth factor-1 exerts time-dependent stabilization of adherens junctions following VEGF-induced vascular permeability. PLoS One. 2011; 6(3):e18076.
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Grant, MA. Drug Develop Res. Integrating computational protein function prediction into drug discovery initiatives. 2011; 17(1):4-16.
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Grant MA. Protein structure prediction in structure-based ligand design and virtual screening. Comb Chem High Throughput Screen. 2009 Dec; 12(10):940-60.
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Grant MA, Baron RM, Macias AA, Layne MD, Perrella MA, Rigby AC. Netropsin improves survival from endotoxaemia by disrupting HMGA1 binding to the NOS2 promoter. Biochem J. 2009 Feb 15; 418(1):103-12.
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Grant MA. A protein structure prediction method in structure-based ligand design and virtual screening. 2009.
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Caballero S, Swaney J, Moreno K, Afzal A, Kielczewski J, Stoller G, Cavalli A, Garland W, Hansen G, Sabbadini R, Grant MB. Anti-sphingosine-1-phosphate monoclonal antibodies inhibit angiogenesis and sub-retinal fibrosis in a murine model of laser-induced choroidal neovascularization. Exp Eye Res. 2009 Mar; 88(3):367-77.
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Sato W, Kosugi T, Zhang L, Roncal CA, Heinig M, Campbell-Thompson M, Yuzawa Y, Atkinson MA, Grant MB, Croker BP, Nakagawa T. The pivotal role of VEGF on glomerular macrophage infiltration in advanced diabetic nephropathy. Lab Invest. 2008 Sep; 88(9):949-61.
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Santulli RJ, Kinney WA, Ghosh S, Decorte BL, Liu L, Tuman RW, Zhou Z, Huebert N, Bursell SE, Clermont AC, Grant MB, Shaw LC, Mousa SA, Galemmo RA, Johnson DL, Maryanoff BE, Damiano BP. Studies with an orally bioavailable alpha V integrin antagonist in animal models of ocular vasculopathy: retinal neovascularization in mice and retinal vascular permeability in diabetic rats. J Pharmacol Exp Ther. 2008 Mar; 324(3):894-901.
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Grant MA, Lazo ND, Lomakin A, Condron MM, Arai H, Yamin G, Rigby AC, Teplow DB. Familial Alzheimer's disease mutations alter the stability of the amyloid beta-protein monomer folding nucleus. Proc Natl Acad Sci U S A. 2007 Oct 16; 104(42):16522-7.
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Grant MA, Shanmugasundaram K, Rigby AC. Conotoxin therapeutics: a pipeline for success? Expert Opin Drug Discov. 2007 Apr; 2(4):453-68.
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Grant MA, Shanmugasundaram K, Rigby AC. Conotoxin Therapeutics: A Pipline for Success?. 2007; 2(4):453-468.
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MacDonald BA, Sund M, Grant MA, Pfaff KL, Holthaus K, Zon LI, Kalluri R. Zebrafish to humans: evolution of the alpha3-chain of type IV collagen and emergence of the autoimmune epitopes associated with Goodpasture syndrome. Blood. 2006 Mar 1; 107(5):1908-15.
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Lazo ND, Grant MA, Condron MC, Rigby AC, Teplow DB. On the nucleation of amyloid beta-protein monomer folding. Protein Sci. 2005 Jun; 14(6):1581-96.
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Grant MA, Kalluri R. Structural basis for the functions of endogenous angiogenesis inhibitors. Cold Spring Harb Symp Quant Biol. 2005; 70:399-410.
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Grant MA, Baikeev RF, Gilbert GE, Rigby AC. Lysine 5 and phenylalanine 9 of the factor IX omega-loop interact with phosphatidylserine in a membrane-mimetic environment. Biochemistry. 2004 Dec 14; 43(49):15367-78.
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Guthrie SM, Curtis LM, Mames RN, Simon GG, Grant MB, Scott EW. The nitric oxide pathway modulates hemangioblast activity of adult hematopoietic stem cells. Blood. 2005 Mar 1; 105(5):1916-22.
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Grant MA, Morelli XJ, Rigby AC. Conotoxins and structural biology: a prospective paradigm for drug discovery. Curr Protein Pept Sci. 2004 Aug; 5(4):235-48.
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Grant MA, Hansson K, Furie BC, Furie B, Stenflo J, Rigby AC. The metal-free and calcium-bound structures of a gamma-carboxyglutamic acid-containing contryphan from Conus marmoreus, glacontryphan-M. J Biol Chem. 2004 Jul 30; 279(31):32464-73.
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Rigby AC, Grant MA. Protein S: a conduit between anticoagulation and inflammation. Crit Care Med. 2004 May; 32(5 Suppl):S336-41.
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Huang M, Rigby AC, Morelli X, Grant MA, Huang G, Furie B, Seaton B, Furie BC. Structural basis of membrane binding by Gla domains of vitamin K-dependent proteins. Nat Struct Biol. 2003 Sep; 10(9):751-6.
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Zeng H, Moise L, Grant MA, Hawrot E. The solution structure of the complex formed between alpha-bungarotoxin and an 18-mer cognate peptide derived from the alpha 1 subunit of the nicotinic acetylcholine receptor from Torpedo californica. J Biol Chem. 2001 Jun 22; 276(25):22930-40.
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Grant MA, Gentile LN, Shi QL, Pellegrini M, Hawrot E. Expression and spectroscopic analysis of soluble nicotinic acetylcholine receptor fragments derived from the extracellular domain of the alpha-subunit. Biochemistry. 1999 Aug 17; 38(33):10730-42.
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Spura A, Russin TS, Freedman ND, Grant M, McLaughlin JT, Hawrot E. Probing the agonist domain of the nicotinic acetylcholine receptor by cysteine scanning mutagenesis reveals residues in proximity to the alpha-bungarotoxin binding site. Biochemistry. 1999 Apr 20; 38(16):4912-21.
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Kadowaki H, Grant MA. Relationship of membrane phospholipid composition, lactosylceramide molecular species, and the specificity of CMP-N-acetylneuraminate:lactosylceramide alpha 2,3-sialyltransferase to the molecular species composition of GM3 ganglioside. J Lipid Res. 1995 Jun; 36(6):1274-82.
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Kadowaki H, Grant MA, Seyfried TN. Effect of Golgi membrane phospholipid composition on the molecular species of GM3 gangliosides synthesized by rat liver sialyltransferase. J Lipid Res. 1994 Nov; 35(11):1956-64.
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Kadowaki H, Grant MA. Preparation of defined molecular species of lactosylceramide by chemical deacylation and reacylation with N-succinimidyl fatty acid esters. Lipids. 1994 Oct; 29(10):721-5.
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Kadowaki H, Grant MA. Mechanism of GM3 ganglioside synthesis. Kinetic study of rat liver CMP-N-neuraminate:lactosylceramide alpha 2,3-sialyltransferase employing 19 molecular species of lactosylceramide. J Biol Chem. 1994 May 27; 269(21):14931-8.
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Kadowaki H, Grant MA, Williams LA. Effect of membrane lipids on the lactosylceramide molecular species specificity of CMP-N-acetylneuraminate:lactosylceramide sialyltransferase. J Lipid Res. 1993 Jun; 34(6):905-14.
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