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Last Name
Institution

Kelan Tantisira, M.D.

TitleAssistant Professor of Medicine
InstitutionBrigham and Women's Hospital
DepartmentMedicine
AddressBrigham and Women's Hospital
Channing Division of Network Medicine, Rm 458
181 Longwood Ave
Boston MA 02115
Phone617/525-0863
Fax617/525-0958

 Bibliographic 
 selected publications
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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  1. Kho AT, Sharma S, Qiu W, Gaedigk R, Klanderman B, Niu S, Anderson C, Leeder JS, Weiss ST, Tantisira KG. Vitamin D related genes in lung development and asthma pathogenesis. BMC Med Genomics. 2013; 6:47.
    View in: PubMed
  2. Himes BE, Qiu W, Klanderman B, Ziniti J, Senter-Sylvia J, Szefler SJ, Lemanske RF, Zeiger RS, Strunk RC, Martinez FD, Boushey H, Chinchilli VM, Israel E, Mauger D, Koppelman GH, Nieuwenhuis MA, Postma DS, Vonk JM, Rafaels N, Hansel NN, Barnes K, Raby B, Tantisira KG, Weiss ST. ITGB5 and AGFG1 variants are associated with severity of airway responsiveness. BMC Med Genet. 2013; 14:86.
    View in: PubMed
  3. McGeachie MJ, Stahl EA, Himes BE, Pendergrass SA, Lima JJ, Irvin CG, Peters SP, Ritchie MD, Plenge RM, Tantisira KG. Polygenic heritability estimates in pharmacogenetics: focus on asthma and related phenotypes. Pharmacogenet Genomics. 2013 Jun; 23(6):324-8.
    View in: PubMed
  4. Tse SM, Gold DR, Sordillo JE, Hoffman EB, Gillman MW, Rifas-Shiman SL, Fuhlbrigge AL, Tantisira KG, Weiss ST, Litonjua AA. Diagnostic accuracy of the bronchodilator response in children. J Allergy Clin Immunol. 2013 Sep; 132(3):554-559.e5.
    View in: PubMed
  5. Himes BE, Sheppard K, Berndt A, Leme AS, Myers RA, Gignoux CR, Levin AM, Gauderman WJ, Yang JJ, Mathias RA, Romieu I, Torgerson DG, Roth LA, Huntsman S, Eng C, Klanderman B, Ziniti J, Senter-Sylvia J, Szefler SJ, Lemanske RF, Zeiger RS, Strunk RC, Martinez FD, Boushey H, Chinchilli VM, Israel E, Mauger D, Koppelman GH, Postma DS, Nieuwenhuis MA, Vonk JM, Lima JJ, Irvin CG, Peters SP, Kubo M, Tamari M, Nakamura Y, Litonjua AA, Tantisira KG, Raby BA, Bleecker ER, Meyers DA, London SJ, Barnes KC, Gilliland FD, Williams LK, Burchard EG, Nicolae DL, Ober C, Demeo DL, Silverman EK, Paigen B, Churchill G, Shapiro SD, Weiss ST. Integration of Mouse and Human Genome-Wide Association Data Identifies KCNIP4 as an Asthma Gene. PLoS One. 2013; 8(2):e56179.
    View in: PubMed
  6. Blake K, Cury JD, Hossain J, Tantisira K, Wang J, Mougey E, Lima J. Methacholine PC20 in African Americans and whites with asthma with homozygous genotypes at ADRB2 codon 16. Pulm Pharmacol Ther. 2013 Jun; 26(3):342-7.
    View in: PubMed
  7. Vyhlidal CA, Riffel AK, Haley KJ, Sharma S, Dai H, Tantisira KG, Weiss ST, Leeder JS. Cotinine in human placenta predicts induction of gene expression in fetal tissues. Drug Metab Dispos. 2013 Feb; 41(2):305-11.
    View in: PubMed
  8. Lasky-Su J, Himes BE, Raby BA, Klanderman BJ, Sylvia JS, Lange C, Melen E, Martinez FD, Israel E, Gauderman J, Gilliland F, Sleiman P, Hakonarson H, Celedón JC, Soto-Quiros M, Avila L, Lima JJ, Irvin CG, Peters SP, Boushey H, Chinchilli VM, Mauger D, Tantisira K, Weiss ST. HLA-DQ strikes again: Genome-wide association study further confirms HLA-DQ in the diagnosis of asthma among adults. Clin Exp Allergy. 2012 Dec; 42(12):1724-33.
    View in: PubMed
  9. Carpe N, Mandeville I, Kho AT, Qiu W, Martin JG, Tantisira KG, Raby BA, Weiss ST, Kaplan F. Maternal allergen exposure reprograms the developmental lung transcriptome in atopic and normoresponsive rat pups. Am J Physiol Lung Cell Mol Physiol. 2012 Nov 15; 303(10):L899-911.
    View in: PubMed
  10. Dahlin A, Tantisira KG. Integrative systems biology approaches in asthma pharmacogenomics. Pharmacogenomics. 2012 Sep; 13(12):1387-404.
    View in: PubMed
  11. Wu AC, Tantisira K, Li L, Fuhlbrigge AL, Weiss ST, Litonjua A. Effect of vitamin D and inhaled corticosteroid treatment on lung function in children. Am J Respir Crit Care Med. 2012 Sep 15; 186(6):508-13.
    View in: PubMed
  12. Himes BE, Jiang X, Hu R, Wu AC, Lasky-Su JA, Klanderman BJ, Ziniti J, Senter-Sylvia J, Lima JJ, Irvin CG, Peters SP, Meyers DA, Bleecker ER, Kubo M, Tamari M, Nakamura Y, Szefler SJ, Lemanske RF, Zeiger RS, Strunk RC, Martinez FD, Hanrahan JP, Koppelman GH, Postma DS, Nieuwenhuis MA, Vonk JM, Panettieri RA, Markezich A, Israel E, Carey VJ, Tantisira KG, Litonjua AA, Lu Q, Weiss ST. Genome-wide association analysis in asthma subjects identifies SPATS2L as a novel bronchodilator response gene. PLoS Genet. 2012 Jul; 8(7):e1002824.
    View in: PubMed
  13. McGeachie MJ, Wu AC, Chang HH, Lima JJ, Peters SP, Tantisira KG. Predicting inhaled corticosteroid response in asthma with two associated SNPs. Pharmacogenomics J. 2013 Aug; 13(4):306-11.
    View in: PubMed
  14. Tse SM, Kelly HW, Litonjua AA, Van Natta ML, Weiss ST, Tantisira KG. Corticosteroid use and bone mineral accretion in children with asthma: effect modification by vitamin D. J Allergy Clin Immunol. 2012 Jul; 130(1):53-60.e4.
    View in: PubMed
  15. Forno E, Lasky-Su J, Himes B, Howrylak J, Ramsey C, Brehm J, Klanderman B, Ziniti J, Melén E, Pershagen G, Wickman M, Martinez F, Mauger D, Sorkness C, Tantisira K, Raby BA, Weiss ST, Celedón JC. Genome-wide association study of the age of onset of childhood asthma. J Allergy Clin Immunol. 2012 Jul; 130(1):83-90.e4.
    View in: PubMed
  16. Tantisira KG, Damask A, Szefler SJ, Schuemann B, Markezich A, Su J, Klanderman B, Sylvia J, Wu R, Martinez F, Boushey HA, Chinchilli VM, Mauger D, Weiss ST, Israel E. Genome-wide association identifies the T gene as a novel asthma pharmacogenetic locus. Am J Respir Crit Care Med. 2012 Jun 15; 185(12):1286-91.
    View in: PubMed
  17. Mougey EB, Chen C, Tantisira KG, Blake KV, Peters SP, Wise RA, Weiss ST, Lima JJ. Pharmacogenetics of asthma controller treatment. Pharmacogenomics J. 2013 Jun; 13(3):242-50.
    View in: PubMed
  18. Duan QL, Du R, Lasky-Su J, Klanderman BJ, Partch AB, Peters SP, Irvin CG, Hanrahan JP, Lima JJ, Blake KV, Liggett SB, Litonjua AA, Tantisira KG. A polymorphism in the thyroid hormone receptor gene is associated with bronchodilator response in asthmatics. Pharmacogenomics J. 2013 Apr; 13(2):130-6.
    View in: PubMed
  19. Du R, Litonjua AA, Tantisira KG, Lasky-Su J, Sunyaev SR, Klanderman BJ, Celedón JC, Avila L, Soto-Quiros ME, Weiss ST. Genome-wide association study reveals class I MHC-restricted T cell-associated molecule gene (CRTAM) variants interact with vitamin D levels to affect asthma exacerbations. J Allergy Clin Immunol. 2012 Feb; 129(2):368-73, 373.e1-5.
    View in: PubMed
  20. Tse SM, Tantisira K, Weiss ST. The pharmacogenetics and pharmacogenomics of asthma therapy. Pharmacogenomics J. 2011 Dec; 11(6):383-92.
    View in: PubMed
  21. Tantisira KG, Lasky-Su J, Harada M, Murphy A, Litonjua AA, Himes BE, Lange C, Lazarus R, Sylvia J, Klanderman B, Duan QL, Qiu W, Hirota T, Martinez FD, Mauger D, Sorkness C, Szefler S, Lazarus SC, Lemanske RF, Peters SP, Lima JJ, Nakamura Y, Tamari M, Weiss ST. Genomewide association between GLCCI1 and response to glucocorticoid therapy in asthma. N Engl J Med. 2011 Sep 29; 365(13):1173-83.
    View in: PubMed
  22. Wu R, Tong C, Wang Z, Mauger D, Tantisira K, Szefler SJ, Chinchilli VM, Israel E. A conceptual framework for pharmacodynamic genome-wide association studies in pharmacogenomics. Drug Discov Today. 2011 Oct; 16(19-20):884-90.
    View in: PubMed
  23. Hirota T, Takahashi A, Kubo M, Tsunoda T, Tomita K, Doi S, Fujita K, Miyatake A, Enomoto T, Miyagawa T, Adachi M, Tanaka H, Niimi A, Matsumoto H, Ito I, Masuko H, Sakamoto T, Hizawa N, Taniguchi M, Lima JJ, Irvin CG, Peters SP, Himes BE, Litonjua AA, Tantisira KG, Weiss ST, Kamatani N, Nakamura Y, Tamari M. Genome-wide association study identifies three new susceptibility loci for adult asthma in the Japanese population. Nat Genet. 2011 Sep; 43(9):893-6.
    View in: PubMed
  24. Haley KJ, Lasky-Su J, Manoli SE, Smith LA, Shahsafaei A, Weiss ST, Tantisira K. RUNX transcription factors: association with pediatric asthma and modulated by maternal smoking. Am J Physiol Lung Cell Mol Physiol. 2011 Nov; 301(5):L693-701.
    View in: PubMed
  25. Xu M, Tantisira KG, Wu A, Litonjua AA, Chu JH, Himes BE, Damask A, Weiss ST. Genome Wide Association Study to predict severe asthma exacerbations in children using random forests classifiers. BMC Med Genet. 2011; 12:90.
    View in: PubMed
  26. Melén E, Kho AT, Sharma S, Gaedigk R, Leeder JS, Mariani TJ, Carey VJ, Weiss ST, Tantisira KG. Expression analysis of asthma candidate genes during human and murine lung development. Respir Res. 2011; 12:86.
    View in: PubMed
  27. Wu AC, Tantisira K, Li L, Schuemann B, Weiss ST, Fuhlbrigge AL. Predictors of symptoms are different from predictors of severe exacerbations from asthma in children. Chest. 2011 Jul; 140(1):100-7.
    View in: PubMed
  28. Grundberg E, Adoue V, Kwan T, Ge B, Duan QL, Lam KC, Koka V, Kindmark A, Weiss ST, Tantisira K, Mallmin H, Raby BA, Nilsson O, Pastinen T. Global analysis of the impact of environmental perturbation on cis-regulation of gene expression. PLoS Genet. 2011; 7(1):e1001279.
    View in: PubMed
  29. Duan QL, Gaume BR, Hawkins GA, Himes BE, Bleecker ER, Klanderman B, Irvin CG, Peters SP, Meyers DA, Hanrahan JP, Lima JJ, Litonjua AA, Tantisira KG, Liggett SB. Regulatory haplotypes in ARG1 are associated with altered bronchodilator response. Am J Respir Crit Care Med. 2011 Feb 15; 183(4):449-54.
    View in: PubMed
  30. Harada M, Hirota T, Jodo AI, Hitomi Y, Sakashita M, Tsunoda T, Miyagawa T, Doi S, Kameda M, Fujita K, Miyatake A, Enomoto T, Noguchi E, Masuko H, Sakamoto T, Hizawa N, Suzuki Y, Yoshihara S, Adachi M, Ebisawa M, Saito H, Matsumoto K, Nakajima T, Mathias RA, Rafaels N, Barnes KC, Himes BE, Duan QL, Tantisira KG, Weiss ST, Nakamura Y, Ziegler SF, Tamari M. Thymic stromal lymphopoietin gene promoter polymorphisms are associated with susceptibility to bronchial asthma. Am J Respir Cell Mol Biol. 2011 Jun; 44(6):787-93.
    View in: PubMed
  31. Carpe N, Mandeville I, Ribeiro L, Ponton A, Martin JG, Kho AT, Chu JH, Tantisira K, Weiss ST, Raby BA, Kaplan F. Genetic influences on asthma susceptibility in the developing lung. Am J Respir Cell Mol Biol. 2010 Dec; 43(6):720-30.
    View in: PubMed
  32. Welsh M, Mangravite L, Medina MW, Tantisira K, Zhang W, Huang RS, McLeod H, Dolan ME. Pharmacogenomic discovery using cell-based models. Pharmacol Rev. 2009 Dec; 61(4):413-29.
    View in: PubMed
  33. Sharma S, Tantisira K, Carey V, Murphy AJ, Lasky-Su J, Celedón JC, Lazarus R, Klanderman B, Rogers A, Soto-Quirós M, Avila L, Mariani T, Gaedigk R, Leeder S, Torday J, Warburton D, Raby B, Weiss ST. A role for Wnt signaling genes in the pathogenesis of impaired lung function in asthma. Am J Respir Crit Care Med. 2010 Feb 15; 181(4):328-36.
    View in: PubMed
  34. Kho AT, Bhattacharya S, Tantisira KG, Carey VJ, Gaedigk R, Leeder JS, Kohane IS, Weiss ST, Mariani TJ. Transcriptomic analysis of human lung development. Am J Respir Crit Care Med. 2010 Jan 1; 181(1):54-63.
    View in: PubMed
  35. Himes BE, Wu AC, Duan QL, Klanderman B, Litonjua AA, Tantisira K, Ramoni MF, Weiss ST. Predicting response to short-acting bronchodilator medication using Bayesian networks. Pharmacogenomics. 2009 Sep; 10(9):1393-412.
    View in: PubMed
  36. Tantisira KG, Drazen JM. Genetics and pharmacogenetics of the leukotriene pathway. J Allergy Clin Immunol. 2009 Sep; 124(3):422-7.
    View in: PubMed
  37. Rogers AJ, Tantisira KG, Fuhlbrigge AL, Litonjua AA, Lasky-Su JA, Szefler SJ, Strunk RC, Zeiger RS, Weiss ST. Predictors of poor response during asthma therapy differ with definition of outcome. Pharmacogenomics. 2009 Aug; 10(8):1231-42.
    View in: PubMed
  38. Raby BA, Van Steen K, Lasky-Su J, Tantisira K, Kaplan F, Weiss ST. Importin-13 genetic variation is associated with improved airway responsiveness in childhood asthma. Respir Res. 2009; 10:67.
    View in: PubMed
  39. Murphy A, Tantisira KG, Soto-Quirós ME, Avila L, Klanderman BJ, Lake S, Weiss ST, Celedón JC. PRKCA: a positional candidate gene for body mass index and asthma. Am J Hum Genet. 2009 Jul; 85(1):87-96.
    View in: PubMed
  40. Du R, Tantisira K, Carey V, Bhattacharya S, Metje S, Kho AT, Klanderman BJ, Gaedigk R, Lazarus R, Mariani TJ, Leeder JS, Weiss ST. Platform dependence of inference on gene-wise and gene-set involvement in human lung development. BMC Bioinformatics. 2009; 10:189.
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  41. Tantisira KG. In asthma, the apple falls faster than the pear. J Allergy Clin Immunol. 2009 May; 123(5):1075-6.
    View in: PubMed
  42. Tantisira KG, Lima J, Sylvia J, Klanderman B, Weiss ST. 5-lipoxygenase pharmacogenetics in asthma: overlap with Cys-leukotriene receptor antagonist loci. Pharmacogenet Genomics. 2009 Mar; 19(3):244-7.
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  43. Hawkins GA, Lazarus R, Smith RS, Tantisira KG, Meyers DA, Peters SP, Weiss ST, Bleecker ER. The glucocorticoid receptor heterocomplex gene STIP1 is associated with improved lung function in asthmatic subjects treated with inhaled corticosteroids. J Allergy Clin Immunol. 2009 Jun; 123(6):1376-83.e7.
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  44. Tantisira KG, Lima J, Sylvia J, Klanderman B, Weiss ST. 5-lipoxygenase Pharmacogenetics in Asthma: Overlap with CystLTR1 Loci. Pharmacogenet Genomics. 2009; (In Press).
  45. Tantisira KG. Novel approaches to pharmacogenomic investigations. Curr Pharm Des. 2009; 15(32):3732-3.
    View in: PubMed
  46. Murphy A, Lasky-Su J, Tantisira KG, Litonjua AA, Lange C, Weiss ST. Genome-wide association studies of family data in pharmacogenetics: a case study. Curr Pharm Des. 2009; 15(32):3764-72.
    View in: PubMed
  47. Tantisira K, Weiss S. The pharmacogenetics of asthma treatment. Curr Allergy Asthma Rep. 2009 Jan; 9(1):10-7.
    View in: PubMed
  48. Duan QL, Tantisira KG. Pharmacogenetics of asthma therapy. Curr Pharm Des. 2009; 15(32):3742-53.
    View in: PubMed
  49. Lima JJ, Blake KV, Tantisira KG, Weiss ST. Pharmacogenetics of asthma. Curr Opin Pulm Med. 2009 Jan; 15(1):57-62.
    View in: PubMed
  50. Wu AC, Tantisira K, Li L, Schuemann B, Weiss S. Repeatability of response to asthma medications. J Allergy Clin Immunol. 2009 Feb; 123(2):385-90.
    View in: PubMed
  51. Sharma S, Litonjua AA, Tantisira KG, Fuhlbrigge AL, Szefler SJ, Strunk RC, Zeiger RS, Murphy AJ, Weiss ST. Clinical predictors and outcomes of consistent bronchodilator response in the childhood asthma management program. J Allergy Clin Immunol. 2008 Nov; 122(5):921-928.e4.
    View in: PubMed
  52. Tantisira KG, Lazarus R, Litonjua AA, Klanderman B, Weiss ST. Chromosome 17: association of a large inversion polymorphism with corticosteroid response in asthma. Pharmacogenet Genomics. 2008 Aug; 18(8):733-7.
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  53. Litonjua AA, Lasky-Su J, Schneiter K, Tantisira KG, Lazarus R, Klanderman B, Lima JJ, Irvin CG, Peters SP, Hanrahan JP, Liggett SB, Hawkins GA, Meyers DA, Bleecker ER, Lange C, Weiss ST. ARG1 is a novel bronchodilator response gene: screening and replication in four asthma cohorts. Am J Respir Crit Care Med. 2008 Oct 1; 178(7):688-94.
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  54. Tantisira K. Genetic variation in FCER2: implications for children with asthma. Pharmacogenomics. 2008 Jul; 9(7):805-7.
    View in: PubMed
  55. Jones TS, Kaste SC, Liu W, Cheng C, Yang W, Tantisira KG, Pui CH, Relling MV. CRHR1 polymorphisms predict bone density in survivors of acute lymphoblastic leukemia. J Clin Oncol. 2008 Jun 20; 26(18):3031-7.
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  56. Jones TS, Kaste SC, Liu W, Cheng C, Yang W, Tantisira KG, Ching-Hon P, Relling MV. Corticotropin Releasing Hormone Receptor-1 (CRHR1) Polymorphisms Predict Bone Density in Acute Lymphoblastic Leukemia Survivors. J Clin Oncology. 2008; 26(18):3031-7.
  57. Poon AH, Tantisira KG, Litonjua AA, Lazarus R, Xu J, Lasky-Su J, Lima JJ, Irvin CG, Hanrahan JP, Lange C, Weiss ST. Association of corticotropin-releasing hormone receptor-2 genetic variants with acute bronchodilator response in asthma. Pharmacogenet Genomics. 2008 May; 18(5):373-82.
    View in: PubMed
  58. Tantisira KG, Colvin R, Tonascia J, Strunk RC, Weiss ST, Fuhlbrigge AL. Airway responsiveness in mild to moderate childhood asthma: sex influences on the natural history. Am J Respir Crit Care Med. 2008 Aug 15; 178(4):325-31.
    View in: PubMed
  59. Tantisira KG, Silverman ES, Mariani TJ, Xu J, Richter BG, Klanderman BJ, Litonjua AA, Lazarus R, Rosenwasser LJ, Fuhlbrigge AL, Weiss ST. FCER2: a pharmacogenetic basis for severe exacerbations in children with asthma. J Allergy Clin Immunol. 2007 Dec; 120(6):1285-91.
    View in: PubMed
  60. Giacomini KM, Brett CM, Altman RB, Benowitz NL, Dolan ME, Flockhart DA, Johnson JA, Hayes DF, Klein T, Krauss RM, Kroetz DL, McLeod HL, Nguyen AT, Ratain MJ, Relling MV, Reus V, Roden DM, Schaefer CA, Shuldiner AR, Skaar T, Tantisira K, Tyndale RF, Wang L, Weinshilboum RM, Weiss ST, Zineh I. The pharmacogenetics research network: from SNP discovery to clinical drug response. Clin Pharmacol Ther. 2007 Mar; 81(3):328-45.
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  61. Ly NP, Rifas-Shiman SL, Litonjua AA, Tzianabos AO, Schaub B, Ruiz-Pérez B, Tantisira KG, Finn PW, Gillman MW, Weiss ST, Gold DR. Cord blood cytokines and acute lower respiratory illnesses in the first year of life. Pediatrics. 2007 Jan; 119(1):e171-8.
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  62. Tantisira KG, Weiss ST. The pharmacogenetics of asthma therapy. Curr Drug Targets. 2006 Dec; 7(12):1697-708.
    View in: PubMed
  63. Tantisira KG, Gold DR. Adipositas in Infants and Children: A New Disease on the Horizon. U. Frey, J. Gerritsen, editors. European Respiratory Monograph: Respiratory Diseases in Infants and Children. 2006; 11(37):314-344.
  64. Hawkins GA, Tantisira K, Meyers DA, Ampleford EJ, Klanderman B, Liggett SB, Peters SP, Weiss ST, Bleecker ER. Sequence, Haplotype and Association Analysis of ADR{beta}2 in Multi-Ethnic Asthma Case/Control Subjects. Am J Respir Crit Care Med. 2006; 174(10):1101-9.
  65. Litonjua AA, Rifas-Shiman SL, Ly NP, Tantisira KG, Rich-Edwards JW, Camargo CA, Weiss ST, Gillman MW, Gold DR. Maternal antioxidant intake in pregnancy and wheezing illnesses in children at 2 y of age. Am J Clin Nutr. 2006 Oct; 84(4):903-11.
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  66. Tantisira KG, Bleecker ER. Pharmacogenetics. D. Postma, S.T. Weiss, editors. Genetics of Asthma and Chronic Obstructive Pulmonary Disease. 2006; 218:357-397.
  67. Hawkins GA, Tantisira K, Meyers DA, Ampleford EJ, Moore WC, Klanderman B, Liggett SB, Peters SP, Weiss ST, Bleecker ER. Sequence, haplotype, and association analysis of ADRbeta2 in a multiethnic asthma case-control study. Am J Respir Crit Care Med. 2006 Nov 15; 174(10):1101-9.
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  68. Gold DR, Willwerth BM, Tantisira KG, Palmer LJ, Finn PW, Perkins DL, Schroeter C, Gibbons F, Schuab B, Campos H, Gillman MW, Weiss ST. Association of Cord Blood Fatty Acids with Lymphocyte Proliferation, IL-13 and Interferon Gamma. J Allergy Clin Immunol. 2006; 117(4):931-8.
  69. Tantisira KG, Fuhlbrigge AL, Tonascia J, Van Natta M, Zeiger RS, Strunk RC, Szefler SJ, Weiss ST. Bronchodilation and bronchoconstriction: predictors of future lung function in childhood asthma. J Allergy Clin Immunol. 2006 Jun; 117(6):1264-71.
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  70. Weiss ST, Litonjua AA, Lange C, Lazarus R, Liggett SB, Bleecker ER, Tantisira KG. Overview of the pharmacogenetics of asthma treatment. Pharmacogenomics J. 2006 Sep-Oct; 6(5):311-26.
    View in: PubMed
  71. Tantisira KG, Schneiter K, Litonjua AA, Lazarus R, Raby B, Silverman EK, Klanderman B, Lange C, Weiss ST. Identification of Novel Asthma Susceptibility Loci Using a Family-Based Screening Approach. Proceedings of the American Thoracic Society. 2006; 3:A351.
  72. Tantisira KG, Schneiter K, Litonjua AA, Su J, Lange C, Klanderman B, Lazarus R, Weiss ST. Asthma Pharmacogenetics: Novel Steroid Response Genes Identified Via a Family-Based Screening Approach. Proceedings of the American Thoracic Society. 2006; 3:A214.
  73. Willwerth BM, Schaub B, Tantisira KG, Gold DR, Palmer LJ, Litonjua AA, Perkins DL, Schroeter C, Gibbons FK, Gillman MW, Weiss ST, Finn PW. Prenatal, perinatal, and heritable influences on cord blood immune responses. Ann Allergy Asthma Immunol. 2006 Mar; 96(3):445-53.
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  74. Gold DR, Willwerth BM, Tantisira KG, Finn PW, Schaub B, Perkins DL, Tzianabos A, Ly NP, Schroeter C, Gibbons F, Campos H, Oken E, Gillman MW, Palmer LJ, Ryan LM, Weiss ST. Associations of cord blood fatty acids with lymphocyte proliferation, IL-13, and IFN-gamma. J Allergy Clin Immunol. 2006 Apr; 117(4):931-8.
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  75. Lima JJ, Zhang S, Grant A, Shao L, Tantisira KG, Allayee H, Wang J, Sylvester J, Holbrook J, Wise R, Weiss ST, Barnes K. Influence of leukotriene pathway polymorphisms on response to montelukast in asthma. Am J Respir Crit Care Med. 2006 Feb 15; 173(4):379-85.
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  76. Tantisira KG, Drazen JM. Pharmacogenetics. EK Silverman, S Shapiro, and ST Weiss, editors. Respiratory Genetics. 2005; 191-216.
  77. Raby BA, Hwang ES, Van Steen K, Tantisira K, Peng S, Litonjua A, Lazarus R, Giallourakis C, Rioux JD, Sparrow D, Silverman EK, Glimcher LH, Weiss ST. T-bet polymorphisms are associated with asthma and airway hyperresponsiveness. Am J Respir Crit Care Med. 2006 Jan 1; 173(1):64-70.
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  78. Schaub B, Tantisira KG, Gibbons FK, He H, Litonjua AA, Gillman MW, Weiss S, Perkins DL, Gold DR, Finn PW. Fetal cord blood: aspects of heightened immune responses. J Clin Immunol. 2005 Jul; 25(4):329-37.
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  79. Litonjua AA, Tantisira KG, Lake S, Lazarus R, Richter BG, Gabriel S, Silverman ES, Weiss ST. Polymorphisms in signal transducer and activator of transcription 3 and lung function in asthma. Respir Res. 2005; 6:52.
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  80. Tantisira KG, Weiss ST. The pharmacogenetics of asthma: an update. Curr Opin Mol Ther. 2005 Jun; 7(3):209-17.
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  81. Tantisira KG, Small KM, Litonjua AA, Weiss ST, Liggett SB. Molecular properties and pharmacogenetics of a polymorphism of adenylyl cyclase type 9 in asthma: interaction between beta-agonist and corticosteroid pathways. Hum Mol Genet. 2005 Jun 15; 14(12):1671-7.
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  82. Tam EK, Kunimoto J, Labrenz S, Sutherland J, Chen YL, Sutton AJ, Elias T, Tantisira K, Dockery DW, Avol E . Concentration and Acidity of Airborne Particulate Matter in Communities on the Big Island of Hawaii. Proceedings of the American Thoracic Society. 2005; 2:A264.
  83. Levy H, Raby BA, Lake S, Tantisira KG, Kwiatkowski D, Lazarus R, Silverman EK, Richter B, Klimecki WT, Vercelli D, Martinez FD, Weiss ST. Association of defensin beta-1 gene polymorphisms with asthma. J Allergy Clin Immunol. 2005 Feb; 115(2):252-8.
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  84. Silverman ES, Lake SL, Tantisira KG, Richter BG, Litonjua AA, Lazarus R, Valone J, Shore SA, Weiss ST. Association of corticotropin releasing factor receptor-2 variants with response to inhaled glucocorticoids in asthma. Clinical Pharmacology and Therapeutics. 2005; 77(2):P8.
  85. Tantisira KG, Hwang ES, Raby BA, Silverman ES, Lake SL, Richter BG, Peng SL, Drazen JM, Glimcher LH, Weiss ST. TBX21: a functional variant predicts improvement in asthma with the use of inhaled corticosteroids. Proc Natl Acad Sci U S A. 2004 Dec 28; 101(52):18099-104.
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  86. Licinio J, O'Kirwan F, Irizarry K, Merriman B, Thakur S, Jepson R, Lake S, Tantisira KG, Weiss ST, Wong ML. Association of a corticotropin-releasing hormone receptor 1 haplotype and antidepressant treatment response in Mexican-Americans. Mol Psychiatry. 2004 Dec; 9(12):1075-82.
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  87. Silverman ES, Breault DT, Vallone J, Subramanian S, Yilmaz AD, Mathew S, Subramaniam V, Tantisira K, Pacák K, Weiss ST, Majzoub JA. Corticotropin-releasing hormone deficiency increases allergen-induced airway inflammation in a mouse model of asthma. J Allergy Clin Immunol. 2004 Oct; 114(4):747-54.
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  88. Tantisira K, Klimecki WT, Lazarus R, Palmer LJ, Raby BA, Kwiatkowski DJ, Silverman E, Vercelli D, Martinez FD, Weiss ST. Toll-like receptor 6 gene (TLR6): single-nucleotide polymorphism frequencies and preliminary association with the diagnosis of asthma. Genes Immun. 2004 Aug; 5(5):343-6.
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  89. Litonjua AA, Silverman EK, Tantisira KG, Sparrow D, Sylvia JS, Weiss ST. Beta 2-adrenergic receptor polymorphisms and haplotypes are associated with airways hyperresponsiveness among nonsmoking men. Chest. 2004 Jul; 126(1):66-74.
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  90. Tam EK, Kunimoto J, Labrenz S, Sutherland J, Chen YL, Sutton AJ, Elias T, Avol E, Dockery D, Tantisira K. Hawaii Island Children's Lung Assessment Scientific Study (HICLASS). Neurotoxicology. 2004; 25(4):725-6.
  91. Tantisira KG, Lake S, Silverman ES, Palmer LJ, Lazarus R, Silverman EK, Liggett SB, Gelfand EW, Rosenwasser LJ, Richter B, Israel E, Wechsler M, Gabriel S, Altshuler D, Lander E, Drazen J, Weiss ST. Corticosteroid pharmacogenetics: association of sequence variants in CRHR1 with improved lung function in asthmatics treated with inhaled corticosteroids. Hum Mol Genet. 2004 Jul 1; 13(13):1353-9.
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  92. Weiss ST, Tantisira KG. Diagnostic Assay and Related Products. 2004.
  93. Weiss ST, Lake SL, Silverman ES, Silverman EK, Richter B, Drazen JM, Tantisira KG. Asthma steroid pharmacogenetics: a study strategy to identify replicated treatment responses. Proc Am Thorac Soc. 2004; 1(4):364-7.
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  94. Tantisira KG, Litonjua AA, Weiss ST, Fuhlbrigge AL. Association of body mass with pulmonary function in the Childhood Asthma Management Program (CAMP). Thorax. 2003 Dec; 58(12):1036-41.
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  95. Silverman ES, Hjoberg J, Palmer LJ, Tantisira KG, Weiss ST, Drazen JM. Application of Pharmacogenetics to the Therapeutics of Asthma. N. Tony Eissa and David Huston, editors. Therapeutic Targets of Airway Inflammation. 2003; 823-838.
  96. Tantisira KG, Willwerth BM, Palmer LJ, Oken E, Finn PW, Perkins D, Schroeter C, Gibbons F, Schuab B, Camargo CA, Gillman MW, Weiss ST, Gold DR. Birth Weight Influences Cord Blood Cytokine Levels. Am J Respir Crit Care Med. 2003; 167:A61.
  97. Lake SL, Lyon H, Tantisira K, Silverman EK, Weiss ST, Laird NM, Schaid DJ. Estimation and tests of haplotype-environment interaction when linkage phase is ambiguous. Hum Hered. 2003; 55(1):56-65.
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  98. Baron RM, Palmer LJ, Tantisira K, Gabriel S, Sonna LA, Le L, Hallock A, Libermann TA, Drazen JM, Weiss ST, Silverman ES. DNA sequence variants in epithelium-specific ETS-2 and ETS-3 are not associated with asthma. Am J Respir Crit Care Med. 2002 Oct 1; 166(7):927-32.
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  99. Tantisira KG, Systrom DM, Ginns LC. An elevated breathing reserve index at the lactate threshold is a predictor of mortality in patients with cystic fibrosis awaiting lung transplantation. Am J Respir Crit Care Med. 2002 Jun 15; 165(12):1629-33.
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  100. Stanchina ML, Tantisira KG, Aquino SL, Wain JC, Ginns LC. Association of lung perfusion disparity and mortality in patients with cystic fibrosis awaiting lung transplantation. J Heart Lung Transplant. 2002 Feb; 21(2):217-25.
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  101. Tantisira KG, Weiss ST. Childhood infections and asthma: at the crossroads of the hygiene and Barker hypotheses. Respir Res. 2001; 2(6):324-7.
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  102. Tantisira KG, Weiss ST. Complex interactions in complex traits: obesity and asthma. Thorax. 2001 Sep; 56 Suppl 2:ii64-73.
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