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Last Name
Institution

Charles Lawrence Feldman, SC.D.

TitleLecturer on Medicine
InstitutionBrigham and Women's Hospital
DepartmentMedicine
AddressBrigham and Women's Hospital
Cardiovascular
75 Francis St
Boston MA 02115
Phone617/735-0684
Fax617/734-1874

 Bibliographic 
 selected publications
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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  1. Theron AJ, Steel HC, Tintinger GR, Feldman C, Anderson R. Can the anti-inflammatory activities of ß2-agonists be harnessed in the clinical setting? Drug Des Devel Ther. 2013; 7:1387-98.
    View in: PubMed
  2. Koskinas KC, Chatzizisis YS, Papafaklis MI, Coskun AU, Baker AB, Jarolim P, Antoniadis A, Edelman ER, Stone PH, Feldman CL. Synergistic effect of local endothelial shear stress and systemic hypercholesterolemia on coronary atherosclerotic plaque progression and composition in pigs. Int J Cardiol. 2013 Nov 30; 169(6):394-401.
    View in: PubMed
  3. Waweru P, Anderson R, Steel H, Venter WD, Murdoch D, Feldman C. The prevalence of smoking and the knowledge of smoking hazards and smoking cessation strategies among HIV- positive patients in Johannesburg, South Africa. S Afr Med J. 2013 Nov; 103(11):858-60.
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  4. Bourantas CV, Papafaklis MI, Athanasiou L, Kalatzis FG, Naka KK, Siogkas PK, Takahashi S, Saito S, Fotiadis DI, Feldman CL, Stone PH, Michalis LK. A new methodology for accurate 3-dimensional coronary artery reconstruction using routine intravascular ultrasound and angiographic data: implications for widespread assessment of endothelial shear stress in humans. EuroIntervention. 2013 Sep 22; 9(5):582-93.
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  5. Feldman C, Abdulkarim E, Alattar F, Al Lawati F, Al Khatib H, Al Maslamani M, Al Obaidani I, Al Salah M, Farghaly M, Husain EH, Mokadas E. Pneumococcal disease in the Arabian Gulf: Recognizing the challenge and moving toward a solution. J Infect Public Health. 2013 Dec; 6(6):401-9.
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  6. Feldman C, Anderson R. Cigarette smoking and mechanisms of susceptibility to infections of the respiratory tract and other organ systems. J Infect. 2013 Sep; 67(3):169-84.
    View in: PubMed
  7. Koskinas KC, Sukhova GK, Baker AB, Papafaklis MI, Chatzizisis YS, Coskun AU, Quillard T, Jonas M, Maynard C, Antoniadis AP, Shi GP, Libby P, Edelman ER, Feldman CL, Stone PH. Thin-capped atheromata with reduced collagen content in pigs develop in coronary arterial regions exposed to persistently low endothelial shear stress. Arterioscler Thromb Vasc Biol. 2013 Jul; 33(7):1494-504.
    View in: PubMed
  8. Green RJ, Hockman M, Friedman R, Davis M, McDonald M, Seedat R, Els C, Levin M, Potter PC, Feldman C. Chronic rhinitis in South Africa: Update 2013. S Afr Med J. 2013 Jun; 103(6):419-22.
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  9. Feldman C, Anderson R. HIV-Associated Bacterial Pneumonia. Clin Chest Med. 2013 Jun; 34(2):205-16.
    View in: PubMed
  10. Sakamoto S, Takahashi S, Coskun AU, Papafaklis MI, Takahashi A, Saito S, Stone PH, Feldman CL. Relation of distribution of coronary blood flow volume to coronary artery dominance. Am J Cardiol. 2013 May 15; 111(10):1420-4.
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  11. Tintinger GR, Anderson R, Feldman C. Pharmacological approaches to regulate neutrophil activity. Semin Immunopathol. 2013 Jul; 35(4):395-409.
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  12. Makita Y, Nakamura S, Kawasaki T, Takahashi A, Katsuki T, Nakamura S, Namiki A, Hirohata A, Matsumura T, Yamazaki S, Yokoi H, Tanaka S, Otsuji S, Yoshimachi F, Honye J, Harwood D, Reitman M, Coskun AU, Papafaklis MI, Feldman CL. Response to Letter Regarding Article, “Prediction of Progression of Coronary Artery Disease and Clinical Outcomes Using Vascular Profiling of Endothelial Shear Stress and Arterial Plaque Characteristics: The PREDICTION Study”. Circulation. 2013 Mar 12; 127(10):e489-90.
    View in: PubMed
  13. Morar R, Bhayat A, Hammond G, Bruinette H, Feldman C. Inflammatory pseudotumour of the lung: a case report and literature review. Case Rep Radiol. 2012; 2012:214528.
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  14. Lalloo UG, Ainslie GM, Abdool-Gaffar MS, Awotedu AA, Feldman C, Greenblatt M, Irusen EM, Mash R, Naidoo SS, O'Brien J, Otto W, Richards GA, Wong ML, South African Thoracic Society OW. Guideline for the management of acute asthma in adults: 2013 update. S Afr Med J. 2013 Mar; 103(3 Pt 3):189-98.
    View in: PubMed
  15. Brink AJ, Coetzee J, Corcoran C, Clay CG, Hari-Makkan D, Jacobson RK, Richards GA, Feldman C, Nutt L, van Greune J, Deetlefs JD, Swart K, Devenish L, Poirel L, Nordmann P. Emergence of OXA-48 and OXA-181 Carbapenemases among Enterobacteriaceae in South Africa and Evidence of In Vivo Selection of Colistin Resistance as a Consequence of Selective Decontamination of the Gastrointestinal Tract. J Clin Microbiol. 2013 Jan; 51(1):369-72.
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  16. Feldman Ch, Bermas B, Zibit M, Fraser P, Todd Dj, Fortin P, Massarotti E, Costenbader Kh. Designing an intervention for women with systemic lupus erythematosus from medically underserved areas to improve care: a qualitative study. Lupus. 2013; 22(1):52-62.
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  17. Wong EB, Omar T, Setlhako GJ, Osih R, Feldman C, Murdoch DM, Martinson NA, Bangsberg DR, Venter WD. Causes of death on antiretroviral therapy: a post-mortem study from South Africa. PLoS One. 2012; 7(10):e47542.
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  18. Korin N, Kanapathipillai M, Matthews BD, Crescente M, Brill A, Mammoto T, Ghosh K, Jurek S, Bencherif SA, Bhatta D, Coskun AU, Feldman CL, Wagner DD, Ingber DE. Shear-activated nanotherapeutics for drug targeting to obstructed blood vessels. Science. 2012 Aug 10; 337(6095):738-42.
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  19. Wentzel JJ, Chatzizisis YS, Gijsen FJ, Giannoglou GD, Feldman CL, Stone PH. Endothelial shear stress in the evolution of coronary atherosclerotic plaque and vascular remodelling: current understanding and remaining questions. Cardiovasc Res. 2012 Nov 1; 96(2):234-43.
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  20. Steel HC, Theron AJ, Cockeran R, Anderson R, Feldman C. Pathogen- and host-directed anti-inflammatory activities of macrolide antibiotics. Mediators Inflamm. 2012; 2012:584262.
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  21. Stone PH, Saito S, Takahashi S, Makita Y, Nakamura S, Kawasaki T, Takahashi A, Katsuki T, Nakamura S, Namiki A, Hirohata A, Matsumura T, Yamazaki S, Yokoi H, Tanaka S, Otsuji S, Yoshimachi F, Honye J, Harwood D, Reitman M, Coskun AU, Papafaklis MI, Feldman CL. Prediction of progression of coronary artery disease and clinical outcomes using vascular profiling of endothelial shear stress and arterial plaque characteristics: the PREDICTION Study. Circulation. 2012 Jul 10; 126(2):172-81.
    View in: PubMed
  22. Feldman C, Anderson R. Antibiotic resistance of pathogens causing community-acquired pneumonia. Semin Respir Crit Care Med. 2012 Jun; 33(3):232-43.
    View in: PubMed
  23. Brink A, Coetzee J, Clay C, Corcoran C, van Greune J, Deetlefs JD, Nutt L, Feldman C, Richards G, Nordmann P, Poirel L. The spread of carbapenem-resistant Enterobacteriaceae in South Africa: risk factors for acquisition and prevention. S Afr Med J. 2012 Jul; 102(7):599-601.
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  24. Feldman C. The use of antiinflammatory therapy and macrolides in bronchiectasis. Clin Chest Med. 2012 Jun; 33(2):371-80.
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  25. Brink AJ, Botha RF, Poswa X, Senekal M, Badal RE, Grolman DC, Richards GA, Feldman C, Boffard KD, Veller M, Joubert I, Pretorius J. Antimicrobial susceptibility of gram-negative pathogens isolated from patients with complicated intra-abdominal infections in South African hospitals (SMART Study 2004-2009): impact of the new carbapenem breakpoints. Surg Infect (Larchmt). 2012 Feb; 13(1):43-9.
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  26. Borkin MA, Gajos KZ, Peters A, Mitsouras D, Melchionna S, Rybicki FJ, Feldman CL, Pfister H. Evaluation of artery visualizations for heart disease diagnosis. IEEE Trans Vis Comput Graph. 2011 Dec; 17(12):2479-88.
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  27. Nyasulu P, Cohen C, De Gouveia L, Feldman C, Klugman KP, von Gottberg A. Increased risk of death in human immunodeficiency virus-infected children with pneumococcal meningitis in South Africa, 2003-2005. Pediatr Infect Dis J. 2011 Dec; 30(12):1075-80.
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  28. Cockeran R, Mutepe ND, Theron AJ, Tintinger GR, Steel HC, Stivaktas PI, Richards GA, Feldman C, Anderson R. Calcium-dependent potentiation of the pro-inflammatory functions of human neutrophils by tigecycline in vitro. J Antimicrob Chemother. 2012 Jan; 67(1):130-7.
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  29. Takahashi S, Papafaklis MI, Sakamoto S, Antoniadis AP, Coskun AU, Feldman CL, Stone PH. The effect of statins on high-risk atherosclerotic plaque associated with low endothelial shear stress. Curr Opin Lipidol. 2011 Oct; 22(5):358-64.
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  30. Cockeran R, Steel HC, Theron AJ, Mitchell TJ, Feldman C, Anderson R. Characterization of the interactions of the pneumolysoid, ?6 PLY, with human neutrophils in vitro. Vaccine. 2011 Nov 8; 29(48):8780-2.
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  31. Feldman C. Bronchiectasis: new approaches to diagnosis and management. Clin Chest Med. 2011 Sep; 32(3):535-46.
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  32. Stone PH, Feldman CL. In vivo assessment of the risk profile of evolving individual coronary plaques: a step closer. Circulation. 2011 Aug 16; 124(7):763-5.
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  33. Chatzizisis YS, Baker AB, Sukhova GK, Koskinas KC, Papafaklis MI, Beigel R, Jonas M, Coskun AU, Stone BV, Maynard C, Shi GP, Libby P, Feldman CL, Edelman ER, Stone PH. Augmented expression and activity of extracellular matrix-degrading enzymes in regions of low endothelial shear stress colocalize with coronary atheromata with thin fibrous caps in pigs. Circulation. 2011 Feb 15; 123(6):621-30.
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  34. Feldman C, Anderson R. Bacteraemic pneumococcal pneumonia: current therapeutic options. Drugs. 2011 Jan 22; 71(2):131-53.
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  35. Richards G, Levy H, Laterre PF, Feldman C, Woodward B, Bates BM, Qualy RL. CURB-65, PSI, and APACHE II to assess mortality risk in patients with severe sepsis and community acquired pneumonia in PROWESS. J Intensive Care Med. 2011 Jan-Feb; 26(1):34-40.
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  36. Papafaklis MI, Koskinas KC, Chatzizisis YS, Stone PH, Feldman CL. In-vivo assessment of the natural history of coronary atherosclerosis: vascular remodeling and endothelial shear stress determine the complexity of atherosclerotic disease progression. Curr Opin Cardiol. 2010 Nov; 25(6):627-38.
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  37. Stone PH, Feldman CL. In vivo assessment of local intravascular hemodynamics and arterial morphology to investigate vascular outcomes: a growing field coming of age. JACC Cardiovasc Interv. 2010 Nov; 3(11):1199-201.
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  38. Baker AB, Chatzizisis YS, Beigel R, Jonas M, Stone BV, Coskun AU, Maynard C, Rogers C, Koskinas KC, Feldman CL, Stone PH, Edelman ER. Regulation of heparanase expression in coronary artery disease in diabetic, hyperlipidemic swine. Atherosclerosis. 2010 Dec; 213(2):436-42.
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  39. Koskinas KC, Feldman CL, Chatzizisis YS, Coskun AU, Jonas M, Maynard C, Baker AB, Papafaklis MI, Edelman ER, Stone PH. Natural history of experimental coronary atherosclerosis and vascular remodeling in relation to endothelial shear stress: a serial, in vivo intravascular ultrasound study. Circulation. 2010 May 18; 121(19):2092-101.
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  40. Gravett CM, Theron AJ, Steel HC, Tintinger GR, Cockeran R, Feldman C, Anderson R. Interactive inhibitory effects of formoterol and montelukast on activated human neutrophils. Eur Respir J. 2010 Dec; 36(6):1417-24.
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  41. Koskinas KC, Chatzizisis YS, Baker AB, Edelman ER, Stone PH, Feldman CL. The role of low endothelial shear stress in the conversion of atherosclerotic lesions from stable to unstable plaque. Curr Opin Cardiol. 2009 Nov; 24(6):580-90.
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  42. Ramkumar PG, Mitsouras D, Feldman CL, Stone PH, Rybicki FJ. New advances in cardiac computed tomography. Curr Opin Cardiol. 2009 Nov; 24(6):596-603.
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  43. Cockeran R, Mitchell TJ, Feldman C, Anderson R. Pneumolysin induces release of matrix metalloproteinase-8 and -9 from human neutrophils. Eur Respir J. 2009 Nov; 34(5):1167-70.
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  44. Feldman C, Alanee S, Yu VL, Richards GA, Ortqvist A, Rello J, Chiou CC, Chedid MB, Wagener MM, Klugman KP. Severity of illness scoring systems in patients with bacteraemic pneumococcal pneumonia: implications for the intensive care unit care. Clin Microbiol Infect. 2009 Sep; 15(9):850-7.
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  45. Murdoch DM, Suchard MS, Venter WD, Mhlangu P, Ottinger JS, Feldman C, Van Rie A, Glencross DK, Stevens WS, Weinhold KJ. Polychromatic immunophenotypic characterization of T cell profiles among HIV-infected patients experiencing immune reconstitution inflammatory syndrome (IRIS). AIDS Res Ther. 2009; 6:16.
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  46. Bateman E, Feldman C, Mash R, Fairall L, English R, Jithoo A. Systems for the management of respiratory disease in primary care--an international series: South Africa. Prim Care Respir J. 2009 Jun; 18(2):69-75.
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  47. Feldman C, Anderson R. Therapy for pneumococcal bacteremia: monotherapy or combination therapy? Curr Opin Infect Dis. 2009 Apr; 22(2):137-42.
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  48. Feldman C, Anderson R. New insights into pneumococcal disease. Respirology. 2009 Mar; 14(2):167-79.
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  49. Anderson R, Theron AJ, Gravett CM, Steel HC, Tintinger GR, Feldman C. Montelukast inhibits neutrophil pro-inflammatory activity by a cyclic AMP-dependent mechanism. Br J Pharmacol. 2009 Jan; 156(1):105-15.
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  50. Murdoch DM, Venter WD, Feldman C, Van Rie A. HIV immune reconstitution syndrome in sub-Saharan Africa. AIDS. 2008 Aug 20; 22(13):1689-90.
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  51. Chatzizisis YS, Jonas M, Beigel R, Coskun AU, Baker AB, Stone BV, Maynard C, Gerrity RG, Daley W, Edelman ER, Feldman CL, Stone PH. Attenuation of inflammation and expansive remodeling by Valsartan alone or in combination with Simvastatin in high-risk coronary atherosclerotic plaques. Atherosclerosis. 2009 Apr; 203(2):387-94.
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  52. Murdoch DM, Venter WD, Feldman C, Van Rie A. Incidence and risk factors for the immune reconstitution inflammatory syndrome in HIV patients in South Africa: a prospective study. AIDS. 2008 Mar 12; 22(5):601-10.
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  53. Chatzizisis YS, Jonas M, Coskun AU, Beigel R, Stone BV, Maynard C, Gerrity RG, Daley W, Rogers C, Edelman ER, Feldman CL, Stone PH. Prediction of the localization of high-risk coronary atherosclerotic plaques on the basis of low endothelial shear stress: an intravascular ultrasound and histopathology natural history study. Circulation. 2008 Feb 26; 117(8):993-1002.
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  54. Dalal RP, Macphail C, Mqhayi M, Wing J, Feldman C, Chersich MF, Venter WD. Characteristics and outcomes of adult patients lost to follow-up at an antiretroviral treatment clinic in johannesburg, South Africa. J Acquir Immune Defic Syndr. 2008 Jan 1; 47(1):101-7.
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  55. Chatzizisis YS, Coskun AU, Jonas M, Edelman ER, Stone PH, Feldman CL. Risk stratification of individual coronary lesions using local endothelial shear stress: a new paradigm for managing coronary artery disease. Curr Opin Cardiol. 2007 Nov; 22(6):552-64.
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  56. Feldman C, Anderson R. A pivotal role for pneumolysin in the immunopathogenesis, treatment and prevention of pneumococcal disease. S Afr Med J. 2007 Nov; 97(11 Pt 3):1141-5.
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  57. Anderson R, Steel HC, Cockeran R, von Gottberg A, de Gouveia L, Klugman KP, Mitchell TJ, Feldman C. Comparison of the effects of macrolides, amoxicillin, ceftriaxone, doxycycline, tobramycin and fluoroquinolones, on the production of pneumolysin by Streptococcus pneumoniae in vitro. J Antimicrob Chemother. 2007 Nov; 60(5):1155-8.
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  58. Fickl H, Theron AJ, Anderson R, Mitchell TJ, Feldman C. Palladium attenuates the pro-inflammatory interactions of C5a, interleukin-8 and pneumolysin with human neutrophils. J Immunotoxicol. 2007 Jul; 4(3):247-52.
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  59. Chatzizisis YS, Coskun AU, Jonas M, Edelman ER, Feldman CL, Stone PH. Role of endothelial shear stress in the natural history of coronary atherosclerosis and vascular remodeling: molecular, cellular, and vascular behavior. J Am Coll Cardiol. 2007 Jun 26; 49(25):2379-93.
    View in: PubMed
  60. Feldman C, Klugman KP, Yu VL, Ortqvist A, Choiu CC, Chedid MB, Rello J, Wagener M. Bacteraemic pneumococcal pneumonia: impact of HIV on clinical presentation and outcome. J Infect. 2007 Aug; 55(2):125-35.
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  61. Murdoch DM, Venter WD, Van Rie A, Feldman C. Immune reconstitution inflammatory syndrome (IRIS): review of common infectious manifestations and treatment options. AIDS Res Ther. 2007; 4:9.
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  62. Sandler SG, Langeberg A, DeBandi L, Gibble J, Wilson C, Feldman CL. Radiofrequency identification technology can standardize and document blood collections and transfusions. Transfusion. 2007 May; 47(5):763-70.
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  63. Feldman C. Prognostic scoring systems: which one is best? Curr Opin Infect Dis. 2007 Apr; 20(2):165-9.
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  64. Stone PH, Coskun AU, Kinlay S, Popma JJ, Sonka M, Wahle A, Yeghiazarians Y, Maynard C, Kuntz RE, Feldman CL. Regions of low endothelial shear stress are the sites where coronary plaque progresses and vascular remodelling occurs in humans: an in vivo serial study. Eur Heart J. 2007 Mar; 28(6):705-10.
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  65. Anderson R, Steel HC, Cockeran R, Smith AM, von Gottberg A, de Gouveia L, Brink A, Klugman KP, Mitchell TJ, Feldman C. Clarithromycin alone and in combination with ceftriaxone inhibits the production of pneumolysin by both macrolide-susceptible and macrolide-resistant strains of Streptococcus pneumoniae. J Antimicrob Chemother. 2007 Feb; 59(2):224-9.
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  66. Sejersten M, Wagner GS, Pahlm O, Warren JW, Feldman CL, Horácek BM. Detection of acute ischemia from the EASI-derived 12-lead electrocardiogram and from the 12-lead electrocardiogram acquired in clinical practice. J Electrocardiol. 2007 Apr; 40(2):120-6.
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  67. Feldman C, Anderson R. Controversies in the treatment of pneumococcal community-acquired pneumonia. Future Microbiol. 2006 Oct; 1(3):271-81.
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  68. Feldman C, Cockeran R, Jedrzejas MJ, Mitchell TJ, Anderson R. Hyaluronidase augments pneumolysin-mediated injury to human ciliated epithelium. Int J Infect Dis. 2007 Jan; 11(1):11-5.
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  69. Mashalane MB, Stewart A, Feldman C, Becker P, de Charmoy S. Prevalence of exercise-induced bronchospasm in Thokoza schoolchildren. S Afr Med J. 2006 Jan; 96(1):67-70.
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  70. Francois Venter WD, Panz VR, Feldman C, Joffe BI. Adrenocortical function in hospitalised patients with active pulmonary tuberculosis receiving a rifampicin-based regimen -- a pilot study. S Afr Med J. 2006 Jan; 96(1):62-6.
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  71. Sejersten M, Pahlm O, Pettersson J, Zhou S, Maynard C, Feldman CL, Wagner GS. Comparison of EASI-derived 12-lead electrocardiograms versus paramedic-acquired 12-lead electrocardiograms using Mason-Likar limb lead configuration in patients with chest pain. J Electrocardiol. 2006 Jan; 39(1):13-21.
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  72. Feldman CL, Coskun AU, Yeghiazarians Y, Kinlay S, Wahle A, Olszewski ME, Rossen JD, Sonka M, Popma JJ, Orav J, Kuntz RE, Stone PH. Remodeling characteristics of minimally diseased coronary arteries are consistent along the length of the artery. Am J Cardiol. 2006 Jan 1; 97(1):13-6.
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  73. Feldman CL, Milstein SZ, Neubecker D, Underhill BK, Moyer E, Glumm S, Womble M, Auer J, Maynard C, Serra RK, Wagner GS. Comparison of the five-electrode-derived EASI electrocardiogram to the Mason Likar electrocardiogram in the prehospital setting. Am J Cardiol. 2005 Aug 1; 96(3):453-6.
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  74. Smith AM, Feldman C, Massidda O, McCarthy K, Ndiweni D, Klugman KP. Altered PBP 2A and its role in the development of penicillin, cefotaxime, and ceftriaxone resistance in a clinical isolate of Streptococcus pneumoniae. Antimicrob Agents Chemother. 2005 May; 49(5):2002-7.
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  75. Cockeran R, Anderson R, Feldman C. Pneumolysin as a vaccine and drug target in the prevention and treatment of invasive pneumococcal disease. Arch Immunol Ther Exp (Warsz). 2005 May-Jun; 53(3):189-98.
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  76. Feldman C, Theron A, Anderson R. Neutrophils potentiate platinum-mediated injury to human ciliated epithelium in vitro. Inhal Toxicol. 2005 May; 17(6):297-301.
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  77. Feldman C. Pneumonia associated with HIV infection. Curr Opin Infect Dis. 2005 Apr; 18(2):165-70.
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  78. Schleicher GK, Herbert V, Brink A, Martin S, Maraj R, Galpin JS, Feldman C. Procalcitonin and C-reactive protein levels in HIV-positive subjects with tuberculosis and pneumonia. Eur Respir J. 2005 Apr; 25(4):688-92.
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  79. Cockeran R, Theron AJ, Feldman C, Mitchel TJ, Anderson R. Pneumolysin potentiates oxidative inactivation of alpha-1-proteinase inhibitor by activated human neutrophils. Respir Med. 2004 Sep; 98(9):865-71.
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  80. Feldman C. Appropriate management of lower respiratory tract infections in primary care. Prim Care Respir J. 2004 Sep; 13(3):159-66.
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  81. Léophonte P, File T, Feldman C. Gemifloxacin once daily for 7 days compared to amoxicillin/clavulanic acid thrice daily for 10 days for the treatment of community-acquired pneumonia of suspected pneumococcal origin. Respir Med. 2004 Aug; 98(8):708-20.
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  82. Feikin DR, Feldman C, Schuchat A, Janoff EN. Global strategies to prevent bacterial pneumonia in adults with HIV disease. Lancet Infect Dis. 2004 Jul; 4(7):445-55.
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  83. Cockeran R, Theron AJ, Feldman C, Mitchell TJ, Anderson R. Docosahexaenoic acid and eicosapentaenoic acid antagonize the proinflammatory interactions of pneumolysin with human neutrophils. Infect Immun. 2004 Jul; 72(7):4327-9.
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  84. Theron AJ, Ramafi GJ, Feldman C, Grimmer H, Visser SS, Anderson R. Effects of platinum and palladium ions on the production and reactivity of neutrophil-derived reactive oxygen species. Free Radic Biol Med. 2004 Jun 1; 36(11):1408-17.
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  85. Schleicher GK, Hopley MJ, Feldman C. CD4 T-lymphocyte subset counts in HIV-seropositive patients during the course of community-acquired pneumonia caused by Streptococcus pneumoniae. Clin Microbiol Infect. 2004 Jun; 10(6):587-9.
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  86. Welinder A, Sörnmo L, Feild DQ, Feldman CL, Pettersson J, Wagner GS, Pahlm O. Comparison of signal quality between EASI and Mason-Likar 12-lead electrocardiograms during physical activity. Am J Crit Care. 2004 May; 13(3):228-34.
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  87. Feldman C. Clinical relevance of antimicrobial resistance in the management of pneumococcal community-acquired pneumonia. J Lab Clin Med. 2004 May; 143(5):269-83.
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  88. Schleicher GK, Feldman C. Dual infection with Streptococcus pneumoniae and Mycobacterium tuberculosis in HIV-seropositive patients with community acquired pneumonia. Int J Tuberc Lung Dis. 2003 Dec; 7(12):1207-8.
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  89. Stone PH, Coskun AU, Yeghiazarians Y, Kinlay S, Popma JJ, Kuntz RE, Feldman CL. Prediction of sites of coronary atherosclerosis progression: In vivo profiling of endothelial shear stress, lumen, and outer vessel wall characteristics to predict vascular behavior. Curr Opin Cardiol. 2003 Nov; 18(6):458-70.
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  90. Coskun AU, Yeghiazarians Y, Kinlay S, Clark ME, Ilegbusi OJ, Wahle A, Sonka M, Popma JJ, Kuntz RE, Feldman CL, Stone PH. Reproducibility of coronary lumen, plaque, and vessel wall reconstruction and of endothelial shear stress measurements in vivo in humans. Catheter Cardiovasc Interv. 2003 Sep; 60(1):67-78.
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  91. Stone PH, Coskun AU, Kinlay S, Clark ME, Sonka M, Wahle A, Ilegbusi OJ, Yeghiazarians Y, Popma JJ, Orav J, Kuntz RE, Feldman CL. Effect of endothelial shear stress on the progression of coronary artery disease, vascular remodeling, and in-stent restenosis in humans: in vivo 6-month follow-up study. Circulation. 2003 Jul 29; 108(4):438-44.
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  92. Yu VL, Chiou CC, Feldman C, Ortqvist A, Rello J, Morris AJ, Baddour LM, Luna CM, Snydman DR, Ip M, Ko WC, Chedid MB, Andremont A, Klugman KP. An international prospective study of pneumococcal bacteremia: correlation with in vitro resistance, antibiotics administered, and clinical outcome. Clin Infect Dis. 2003 Jul 15; 37(2):230-7.
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  93. Sejersten M, Pahlm O, Pettersson J, Clemmensen PM, Rautaharju F, Zhou S, Maynard C, Feldman CL, Wagner GS. The relative accuracies of ECG precordial lead waveforms derived from EASI leads and those acquired from paramedic applied standard leads. J Electrocardiol. 2003 Jul; 36(3):179-85.
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  94. Morar R, Feldman C. Pulmonary echinococcosis. Eur Respir J. 2003 Jun; 21(6):1069-77.
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  95. Pahlm O, Pettersson J, Thulin A, Feldman CL, Feild DQ, Wagner GS. Comparison of waveforms in conventional 12-lead ECGs and those derived from EASI leads in children. J Electrocardiol. 2003 Jan; 36(1):25-31.
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  96. Schleicher GK, Feldman C, Vermaak Y, Verschoor JA. Prevalence of anti-mycolic acid antibodies in patients with pulmonary tuberculosis co-infected with HIV. Clin Chem Lab Med. 2002 Sep; 40(9):882-7.
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  97. Feldman C, Anderson R, Cockeran R, Mitchell T, Cole P, Wilson R. The effects of pneumolysin and hydrogen peroxide, alone and in combination, on human ciliated epithelium in vitro. Respir Med. 2002 Aug; 96(8):580-5.
    View in: PubMed
  98. Cockeran R, Durandt C, Feldman C, Mitchell TJ, Anderson R. Pneumolysin activates the synthesis and release of interleukin-8 by human neutrophils in vitro. J Infect Dis. 2002 Aug 15; 186(4):562-5.
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  99. Feldman CL, Ilegbusi OJ, Hu Z, Nesto R, Waxman S, Stone PH. Determination of in vivo velocity and endothelial shear stress patterns with phasic flow in human coronary arteries: a methodology to predict progression of coronary atherosclerosis. Am Heart J. 2002 Jun; 143(6):931-9.
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  100. Cockeran R, Anderson R, Feldman C. The role of pneumolysin in the pathogenesis of Streptococcus pneumoniae infection. Curr Opin Infect Dis. 2002 Jun; 15(3):235-9.
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  101. Feild DQ, Feldman CL, Horácek BM. Improved EASI coefficients: their derivation, values, and performance. J Electrocardiol. 2002; 35 Suppl:23-33.
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  102. Rautaharju PM, Zhou SH, Hancock EW, Horácek BM, Feild DQ, Lindauer JM, Wagner GS, Pahlm O, Feldman CL. Comparability of 12-lead ECGs derived from EASI leads with standard 12-lead ECGS in the classification of acute myocardial ischemia and old myocardial infarction. J Electrocardiol. 2002; 35 Suppl:35-9.
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  103. Horácek BM, Warren JW, Feild DQ, Feldman CL. Statistical and deterministic approaches to designing transformations of electrocardiographic leads. J Electrocardiol. 2002; 35 Suppl:41-52.
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  104. Feldman C, Viljoen E, Morar R, Richards G, Sawyer L, Goolam Mahomed A. Prognostic factors in severe community-acquired pneumonia in patients without co-morbid illness. Respirology. 2001 Dec; 6(4):323-30.
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  105. Feldman C. Pneumonia in the elderly. Med Clin North Am. 2001 Nov; 85(6):1441-59.
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  106. Feldman C, Anderson R, Theron AJ, Steel HC, van Rensburg CE, Cole PJ, Wilson R. Vitamin E attenuates the injurious effects of bioactive phospholipids on human ciliated epithelium in vitro. Eur Respir J. 2001 Jul; 18(1):122-9.
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  107. Cockeran R, Steel HC, Mitchell TJ, Feldman C, Anderson R. Pneumolysin potentiates production of prostaglandin E(2) and leukotriene B(4) by human neutrophils. Infect Immun. 2001 May; 69(5):3494-6.
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  108. Klugman KP, Feldman C. Streptococcus pneumoniae respiratory tract infections. Curr Opin Infect Dis. 2001 Apr; 14(2):173-9.
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  109. Feldman C, White H, O'Grady J, Flitcroft A, Briggs A, Richards G. An open, randomised, multi-centre study comparing the safety and efficacy of sitafloxacin and imipenem/cilastatin in the intravenous treatment of hospitalised patients with pneumonia. Int J Antimicrob Agents. 2001 Mar; 17(3):177-88.
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  110. Cockeran R, Theron AJ, Steel HC, Matlola NM, Mitchell TJ, Feldman C, Anderson R. Proinflammatory interactions of pneumolysin with human neutrophils. J Infect Dis. 2001 Feb 15; 183(4):604-11.
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  111. Horácek BM, Warren JW, Penney CJ, MacLeod RS, Title LM, Gardner MJ, Feldman CL. Optimal electrocardiographic leads for detecting acute myocardial ischemia. J Electrocardiol. 2001; 34 Suppl:97-111.
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  112. Feldman C, Vitola D, Schiavo N. Detection of coronary artery disease based on the calcification index obtained by helical computed tomography. Arq Bras Cardiol. 2000 Dec; 75(6):471-80.
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  113. Feldman CL, Stone PH. Intravascular hemodynamic factors responsible for progression of coronary atherosclerosis and development of vulnerable plaque. Curr Opin Cardiol. 2000 Nov; 15(6):430-40.
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  114. Theron AJ, Feldman C, Anderson R. Investigation of the anti-inflammatory and membrane-stabilizing potential of spiramycin in vitro. J Antimicrob Chemother. 2000 Aug; 46(2):269-71.
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  115. Horácek BM, Warren JW, Stóvícek P, Feldman CL. Diagnostic accuracy of derived versus standard 12-lead electrocardiograms. J Electrocardiol. 2000; 33 Suppl:155-60.
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  116. Kirshbom PM, Kherani AR, Onaitis MW, Hata A, Kehoe TE, Feldman C, Feldman JM, Tyler DS. Foregut carcinoids: a clinical and biochemical analysis. Surgery. 1999 Dec; 126(6):1105-10.
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  117. Ilegbusi OJ, Hu Z, Nesto R, Waxman S, Cyganski D, Kilian J, Stone PH, Feldman CL. Determination of blood flow and endothelial shear stress in human coronary artery in vivo. J Invasive Cardiol. 1999 Nov; 11(11):667-74.
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  118. Ramafi G, Anderson R, Theron A, Feldman C, Taylor GW, Wilson R, Cole PJ. Exposure of N-formyl-L-methionyl-L-leucyl-L-phenylalanine-activated human neutrophils to the Pseudomonas aeruginosa-derived pigment 1-hydroxyphenazine is associated with impaired calcium efflux and potentiation of primary granule enzyme release. Infect Immun. 1999 Oct; 67(10):5157-62.
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  119. Feldman C. Pneumonia in the elderly. Clin Chest Med. 1999 Sep; 20(3):563-73.
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  120. Feldman C, Glatthaar M, Morar R, Mahomed AG, Kaka S, Cassel M, Klugman KP. Bacteremic pneumococcal pneumonia in HIV-seropositive and HIV-seronegative adults. Chest. 1999 Jul; 116(1):107-14.
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  121. Klugman KP, Feldman C. Penicillin- and cephalosporin-resistant Streptococcus pneumoniae. Emerging treatment for an emerging problem. Drugs. 1999 Jul; 58(1):1-4.
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  122. Feldman C, Anderson R, Theron A, Mokgobu I, Cole PJ, Wilson R. The effects of ketolides on bioactive phospholipid-induced injury to human respiratory epithelium in vitro. Eur Respir J. 1999 May; 13(5):1022-8.
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  123. Feldman C, Kassel M, Cantrell J, Kaka S, Morar R, Goolam Mahomed A, Philips JI. The presence and sequence of endotracheal tube colonization in patients undergoing mechanical ventilation. Eur Respir J. 1999 Mar; 13(3):546-51.
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  124. Mahomed AG, Murray J, Klempman S, Richards G, Feldman C, Levy NT, Smith C, Kallenbach J. Pneumocystis carinii pneumonia in HIV infected patients from South Africa. East Afr Med J. 1999 Feb; 76(2):80-4.
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  125. Solomon A, Feldman C, Kobilski SA. Abdominal findings in AIDS-related pulmonary tuberculosis correlated with associated CD4 levels. Abdom Imaging. 1998 Nov-Dec; 23(6):573-7.
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  126. Feldman C, Anderson R, Theron AJ, Ramafi G, Cole PJ, Wilson R. Roxithromycin, clarithromycin, and azithromycin attenuate the injurious effects of bioactive phospholipids on human respiratory epithelium in vitro. Inflammation. 1997 Dec; 21(6):655-65.
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  127. Green SL, Gaillard MC, Dewar JB, Ludewick H, Song E, Feldman C. Differences in the prevalence of a TaqI RFLP in the 3' flanking region of the alpha 1-proteinase inhibitor gene between asthmatic and non-asthmatic black and white South Africans. Clin Genet. 1997 Sep; 52(3):162-6.
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  128. Feldman C. Severe community-acquired pneumonia. Curr Opin Pulm Med. 1997 Mar; 3(2):98-104.
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  129. Nosovitsky VA, Ilegbusi OJ, Jiang J, Stone PH, Feldman CL. Effects of curvature and stenosis-like narrowing on wall shear stress in a coronary artery model with phasic flow. Comput Biomed Res. 1997 Feb; 30(1):61-82.
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  130. Anderson R, Theron AJ, Feldman C. Membrane-stabilizing, anti-inflammatory interactions of macrolides with human neutrophils. Inflammation. 1996 Dec; 20(6):693-705.
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  131. Tsuji H, Larson MG, Venditti FJ, Manders ES, Evans JC, Feldman CL, Levy D. Impact of reduced heart rate variability on risk for cardiac events. The Framingham Heart Study. Circulation. 1996 Dec 1; 94(11):2850-5.
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  132. Tsuji H, Venditti FJ, Manders ES, Evans JC, Larson MG, Feldman CL, Levy D. Determinants of heart rate variability. J Am Coll Cardiol. 1996 Nov 15; 28(6):1539-46.
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  133. Ansell SM, Bedhesi S, Ruff B, Mahomed AG, Richards G, Mer M, Feldman C. Study of critically ill patients with systemic lupus erythematosus. Crit Care Med. 1996 Jun; 24(6):981-4.
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  134. Mahida P, Morar R, Goolam Mahomed A, Song E, Tissandie JP, Feldman C. Cryptococcosis: an unusual cause of endobronchial obstruction. Eur Respir J. 1996 Apr; 9(4):837-9.
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  135. Puren AJ, Feldman C, Savage N, Becker PJ, Smith C. Patterns of cytokine expression in community-acquired pneumonia. Chest. 1995 May; 107(5):1342-9.
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  136. Tsuji H, Venditti FJ, Manders ES, Evans JC, Larson MG, Feldman CL, Levy D. Reduced heart rate variability and mortality risk in an elderly cohort. The Framingham Heart Study. Circulation. 1994 Aug; 90(2):878-83.
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  137. Feldman C, Anderson R, Kanthakumar K, Vargas A, Cole PJ, Wilson R. Oxidant-mediated ciliary dysfunction in human respiratory epithelium. Free Radic Biol Med. 1994 Jul; 17(1):1-10.
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  138. Cubanski D, Cyganski D, Antman EM, Feldman CL. A neural network system for detection of atrial fibrillation in ambulatory electrocardiograms. J Cardiovasc Electrophysiol. 1994 Jul; 5(7):602-8.
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  139. Gaillard MC, Zwi S, Nogueira CM, Ludewick H, Feldman C, Frankel A, Tsilimigras C, Kilroe-Smith TA. Ethnic differences in the occurrence of the M1(ala213) haplotype of alpha-1-antitrypsin in asthmatic and non-asthmatic black and white South Africans. Clin Genet. 1994 Mar; 45(3):122-7.
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  140. Seedat MA, Feldman C, Skoularigis J, Promnitz DA, Smith C, Zwi S. A study of acute community-acquired pneumonia, including details of cardiac changes. Q J Med. 1993 Oct; 86(10):669-75.
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  141. Feldman C, Smith C, Kaka S, de Jong P, Goolam Mahomed A, Frankel A, Koornhof HJ. Factors associated with airway colonisation and invasion due to Klebsiella spp. S Afr Med J. 1993 Sep; 83(9):643-6.
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  142. Kallenbach JM, Frankel AH, Lapinsky SE, Thornton AS, Blott JA, Smith C, Feldman C, Zwi S. Determinants of near fatality in acute severe asthma. Am J Med. 1993 Sep; 95(3):265-72.
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  143. Feldman CL, Jennings R. Minor recorder imperfections can cause artifacts in the RR interval spectrum derived from Holter recordings. J Electrocardiol. 1993 Jul; 26(3):231-3.
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  144. Feldman CL, Olson WH, Hubbelbank M, Mitchell R, Kelso D, Bardy GH. Identification of an implantable defibrillator lead fracture with a new Holter system. Pacing Clin Electrophysiol. 1993 Jun; 16(6):1342-4.
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  145. Gibson CM, Diaz L, Kandarpa K, Sacks FM, Pasternak RC, Sandor T, Feldman C, Stone PH. Relation of vessel wall shear stress to atherosclerosis progression in human coronary arteries. Arterioscler Thromb. 1993 Feb; 13(2):310-5.
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  146. Moody GB, Feldman CL, Bailey JJ. Standards and applicable databases for long-term ECG monitoring. J Electrocardiol. 1993; 26 Suppl:151-5.
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  147. Feldman CL, Olson WH, Hubelbank M, Bardy GH. ICDs, telemetry, and Holter monitoring. A marriage of technologies. J Electrocardiol. 1993; 26 Suppl:58.
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  148. Feldman CL, Hubelbank M. Fusion or confusion on Holter recording. Pacing Clin Electrophysiol. 1992 Feb; 15(2):245-6.
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  149. Feldman C, Kallenbach JM, Levy H, Thorburn JR, Hurwitz MD, Koornhof HJ. Comparison of bacteraemic community-acquired lobar pneumonia due to Streptococcus pneumoniae and Klebsiella pneumoniae in an intensive care unit. Respiration. 1991; 58(5-6):265-70.
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  150. Feldman C, Smith C, Levy H, Ginsburg P, Miller SD, Koornhof HJ. Klebsiella pneumoniae bacteraemia at an urban general hospital. J Infect. 1990 Jan; 20(1):21-31.
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  151. Smith C, Feldman C, Levy H, Kallenbach JM, Zwi S. Cryptogenic fibrosing alveolitis. A study of an indigenous African population. Respiration. 1990; 57(6):364-71.
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  152. Levy H, Feldman C, Sacho H, van der Meulen H, Kallenbach J, Koornhof H. A reevaluation of sputum microscopy and culture in the diagnosis of pulmonary tuberculosis. Chest. 1989 Jun; 95(6):1193-7.
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  153. Feldman C, Kallenbach JM, Levy H, Reinach SG, Hurwitz MD, Thorburn JR, Koornhof HJ. Community-acquired pneumonia of diverse aetiology: prognostic features in patients admitted to an intensive care unit and a "severity of illness" core. Intensive Care Med. 1989; 15(5):302-7.
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  154. Levy H, Feldman C, Wadee AA, Rabson AR. Differentiation of sarcoidosis from tuberculosis using an enzyme-linked immunosorbent assay for the detection of antibodies against Mycobacterium tuberculosis. Chest. 1988 Dec; 94(6):1254-5.
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  155. Levy H, Wadee AA, Feldman C, Rabson AR. Enzyme-linked immunosorbent assay for the detection of antibodies against Mycobacterium tuberculosis in bronchial washings and serum. Chest. 1988 Apr; 93(4):762-6.
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  156. Pincus PS, Kallenbach JM, Hurwitz MD, Clinton C, Feldman C, Abramowitz JA, Zwi S. Transbronchial biopsy during mechanical ventilation. Crit Care Med. 1987 Dec; 15(12):1136-9.
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  157. Kallenbach J, Lewis M, Zaltzman M, Feldman C, Orford A, Zwi S. 'Low-dose' corticosteroid prophylaxis against fat embolism. J Trauma. 1987 Oct; 27(10):1173-6.
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  158. Klein MD, Feldman CL. Ventricular premature beat localization in mitral valve prolapse syndrome. Am Heart J. 1981 Jul; 102(1):138-9.
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  159. Moynihan PF, Parisi AF, Feldman CL. Quantitative detection of regional left ventricular contraction abnormalities by two-dimensional echocardiography. I. Analysis of methods. Circulation. 1981 Apr; 63(4):752-60.
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  160. Parisi AF, Moynihan PF, Folland ED, Feldman CL. Quantitative detection of regional left ventricular contraction abnormalities by two-dimensional echocardiography. II. Accuracy in coronary artery disease. Circulation. 1981 Apr; 63(4):761-7.
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  161. Folland ED, Parisi AF, Moynihan PF, Jones DR, Feldman CL, Tow DE. Assessment of left ventricular ejection fraction and volumes by real-time, two-dimensional echocardiography. A comparison of cineangiographic and radionuclide techniques. Circulation. 1979 Oct; 60(4):760-6.
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  162. Aseltine RG, Feldman CL, Paraskos JA, Moruzzi RL. A simple device for closed loop heart rate control during cardiac rehabilitation. IEEE Trans Biomed Eng. 1979 Aug; 26(8):456-64.
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  163. Hubelbank M, Feldman CL. A 60x computer-based Holter tape processing system. Med Instrum. 1978 Nov-Dec; 12(6):324-6.
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  164. Alexander S, Singer PJ, Feldman CL. Monitoring for ventricular premature beats. N Engl J Med. 1978 Jul 20; 299(3):153.
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  165. Feldman CL, Hubelbank M. Computerized arrhythmia monitoring system. Heart Lung. 1978 Jul-Aug; 7(4):671-2.
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  166. Feldman CL, Hubelbank M. Cardiovascular monitoring in the coronary care unit. Med Instrum. 1977 Sep-Oct; 11(5):288-92.
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  167. Klein MD, Feldman CL, Clark DL, Flessas AP, Ryan TJ, Peura RA. Vectorial characteristics of ventricular extrasystoles stimulated during cardiac catheterization. J Electrocardiol. 1976 Apr; 9(2):103-8.
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  168. Ruberman W, Weinblatt E, Frank CW, Goldberg JD, Shapiro S, Feldman CL. Ventricular premature beats and mortality of men with coronary heart disease. Circulation. 1975 Dec; 52(6 Suppl):III199-203.
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  169. Benson H, Alexander S, Feldman CL. Decreased premature ventricular contractions through use of the relaxation response in patients with stable ischaemic heart-disease. Lancet. 1975 Aug 30; 2(7931):380-2.
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  170. Feldman CL, Amazeen PG, Klein MD, Lown B. Computer detection of ventricular ectopic beats. Comput Biomed Res. 1970 Dec; 3(6):666-74.
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