 Antoine Karnoub, PH.D.
| Title | Assistant Professor of Pathology |
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| Institution | Beth Israel Deaconess Medical Center |
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| Department | Pathology |
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| Address | Beth Israel Deaconess Medical Center
Pathology
330 Brookline Ave
Boston MA 02215
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| Phone | 617/667-4391 |
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| Fax | 617/667-2943 |
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 Bibliographic
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications.
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Thomas C, Karnoub AE. Lysyl oxidase at the crossroads of mesenchymal stem cells and epithelial-mesenchymal transition. Oncotarget. 2013 Mar; 4(3):376-7.
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El-Haibi CP, Bell GW, Zhang J, Collmann AY, Wood D, Scherber CM, Csizmadia E, Mariani O, Zhu C, Campagne A, Toner M, Bhatia SN, Irimia D, Vincent-Salomon A, Karnoub AE. Critical role for lysyl oxidase in mesenchymal stem cell-driven breast cancer malignancy. Proc Natl Acad Sci U S A. 2012 Oct 23; 109(43):17460-5.
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Cuiffo BG, Karnoub AE. Mesenchymal stem cells in tumor development: emerging roles and concepts. Cell Adh Migr. 2012 May-Jun; 6(3):220-30.
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El-Haibi CP, Karnoub AE. Mesenchymal stem cells in the pathogenesis and therapy of breast cancer. J Mammary Gland Biol Neoplasia. 2010 Dec; 15(4):399-409.
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Karnoub AE, Weinberg RA. Ras oncogenes: split personalities. Nat Rev Mol Cell Biol. 2008 Jul; 9(7):517-31.
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Scheel C, Onder T, Karnoub A, Weinberg RA. Adaptation versus selection: the origins of metastatic behavior. Cancer Res. 2007 Dec 15; 67(24):11476-9; discussion 11479-80.
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Karnoub AE, Dash AB, Vo AP, Sullivan A, Brooks MW, Bell GW, Richardson AL, Polyak K, Tubo R, Weinberg RA. Mesenchymal stem cells within tumour stroma promote breast cancer metastasis. Nature. 2007 Oct 4; 449(7162):557-63.
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Ince TA, Richardson AL, Bell GW, Saitoh M, Godar S, Karnoub AE, Iglehart JD, Weinberg RA. Transformation of different human breast epithelial cell types leads to distinct tumor phenotypes. Cancer Cell. 2007 Aug; 12(2):160-70.
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Yohe ME, Rossman KL, Gardner OS, Karnoub AE, Snyder JT, Gershburg S, Graves LM, Der CJ, Sondek J. Auto-inhibition of the Dbl family protein Tim by an N-terminal helical motif. J Biol Chem. 2007 May 4; 282(18):13813-23.
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Karnoub AE, Weinberg RA. Chemokine networks and breast cancer metastasis. Breast Dis. 2006-2007; 26:75-85.
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Singh A, Karnoub AE, Palmby TR, Lengyel E, Sondek J, Der CJ. Rac1b, a tumor associated, constitutively active Rac1 splice variant, promotes cellular transformation. Oncogene. 2004 Dec 16; 23(58):9369-80.
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Palmby TR, Abe K, Karnoub AE, Der CJ. Vav transformation requires activation of multiple GTPases and regulation of gene expression. Mol Cancer Res. 2004 Dec; 2(12):702-11.
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Karnoub AE, Symons M, Campbell SL, Der CJ. Molecular basis for Rho GTPase signaling specificity. Breast Cancer Res Treat. 2004 Mar; 84(1):61-71.
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Pruitt WM, Karnoub AE, Rakauskas AC, Guipponi M, Antonarakis SE, Kurakin A, Kay BK, Sondek J, Siderovski DP, Der CJ. Role of the pleckstrin homology domain in intersectin-L Dbl homology domain activation of Cdc42 and signaling. Biochim Biophys Acta. 2003 Apr 7; 1640(1):61-8.
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Fuentes EJ, Karnoub AE, Booden MA, Der CJ, Campbell SL. Critical role of the pleckstrin homology domain in Dbs signaling and growth regulation. J Biol Chem. 2003 Jun 6; 278(23):21188-96.
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Wennerberg K, Ellerbroek SM, Liu RY, Karnoub AE, Burridge K, Der CJ. RhoG signals in parallel with Rac1 and Cdc42. J Biol Chem. 2002 Dec 6; 277(49):47810-7.
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Hamad NM, Elconin JH, Karnoub AE, Bai W, Rich JN, Abraham RT, Der CJ, Counter CM. Distinct requirements for Ras oncogenesis in human versus mouse cells. Genes Dev. 2002 Aug 15; 16(16):2045-57.
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Thapar R, Karnoub AE, Campbell SL. Structural and biophysical insights into the role of the insert region in Rac1 function. Biochemistry. 2002 Mar 26; 41(12):3875-83.
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Karnoub AE, Worthylake DK, Rossman KL, Pruitt WM, Campbell SL, Sondek J, Der CJ. Molecular basis for Rac1 recognition by guanine nucleotide exchange factors. Nat Struct Biol. 2001 Dec; 8(12):1037-41.
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Lambert JM, Karnoub AE, Graves LM, Campbell SL, Der CJ. Role of MLK3-mediated activation of p70 S6 kinase in Rac1 transformation. J Biol Chem. 2002 Feb 15; 277(7):4770-7.
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Karnoub AE, Der CJ, Campbell SL. The insert region of Rac1 is essential for membrane ruffling but not cellular transformation. Mol Cell Biol. 2001 Apr; 21(8):2847-57.
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