Xueyi Li, M.D.
|Title||Assistant Professor of Neurology|
|Institution||Massachusetts General Hospital|
|Address||Massachusetts General Hospital|
114 16th Street
Charlestown MA 02129
Available: 08/01/12, Expires: 12/30/13
The recycling endosome controls a range of physiological and developmental processes by regulating trafficking of critical proteins to different intracellular pathways. Yet factors that operate in the processes of protein sorting at the recycling endosome are largely unknown. One way to decode these factors is to profile the proteome of pure recycling endosomes that are not able to achieve using current purification methods. The role of the student will participate in isolation of recycling endosomes from cultured cells using an approach newly developed in the faculty's lab and characterization of some proteins unveiled by mass spectrometrical profiling of purified recycling endosomes.
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