Contact, publication, and social network information about Harvard faculty and fellows. Harvard Catalyst Profiles
Keywords
Last Name
Institution

Edward M. Scolnick, M.D.

TitleSenior Lecturer on Genetics
InstitutionHarvard Medical School
DepartmentGenetics
AddressHarvard Medical School
NRB, Dept. of Genetics
77 Avenue Louis Pasteur
Boston MA 02115

 Bibliographic 
 selected publications
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
List All   |   Timeline
  1. Bergen SE, O'Dushlaine CT, Ripke S, Lee PH, Ruderfer DM, Akterin S, Moran JL, Chambert KD, Handsaker RE, Backlund L, Ösby U, McCarroll S, Landen M, Scolnick EM, Magnusson PK, Lichtenstein P, Hultman CM, Purcell SM, Sklar P, Sullivan PF. Genome-wide association study in a Swedish population yields support for greater CNV and MHC involvement in schizophrenia compared with bipolar disorder. Mol Psychiatry. 2012 Sep; 17(9):880-6.
    View in: PubMed
  2. Marder SR, Roth B, Sullivan PF, Scolnick EM, Nestler EJ, Geyer MA, Welnberger DR, Karayiorgou M, Guidotti A, Gingrich J, Akbarian S, Buchanan RW, Lieberman JA, Conn PJ, Haggarty SJ, Law AJ, Campbell B, Krystal JH, Moghaddam B, Sawa A, Saw A, Caron MG, George SR, Allen JA, Solis M. Advancing drug discovery for schizophrenia. Ann N Y Acad Sci. 2011 Oct; 1236:30-43.
    View in: PubMed
  3. Large-scale genome-wide association analysis of bipolar disorder identifies a new susceptibility locus near ODZ4. Nat Genet. 2011 Oct; 43(10):977-83.
    View in: PubMed
  4. Genome-wide association study identifies five new schizophrenia loci. Nat Genet. 2011 Oct; 43(10):969-76.
    View in: PubMed
  5. Kuai L, Ong SE, Madison JM, Wang X, Duvall JR, Lewis TA, Luce CJ, Conner SD, Pearlman DA, Wood JL, Schreiber SL, Carr SA, Scolnick EM, Haggarty SJ. AAK1 identified as an inhibitor of neuregulin-1/ErbB4-dependent neurotrophic factor signaling using integrative chemical genomics and proteomics. Chem Biol. 2011 Jul 29; 18(7):891-906.
    View in: PubMed
  6. Pan JQ, Lewis MC, Ketterman JK, Clore EL, Riley M, Richards KR, Berry-Scott E, Liu X, Wagner FF, Holson EB, Neve RL, Biechele TL, Moon RT, Scolnick EM, Petryshen TL, Haggarty SJ. AKT kinase activity is required for lithium to modulate mood-related behaviors in mice. Neuropsychopharmacology. 2011 Jun; 36(7):1397-411.
    View in: PubMed
  7. Chen X, Lee G, Maher BS, Fanous AH, Chen J, Zhao Z, Guo A, van den Oord E, Sullivan PF, Shi J, Levinson DF, Gejman PV, Sanders A, Duan J, Owen MJ, Craddock NJ, O'Donovan MC, Blackman J, Lewis D, Kirov GK, Qin W, Schwab S, Wildenauer D, Chowdari K, Nimgaonkar V, Straub RE, Weinberger DR, O'Neill FA, Walsh D, Bronstein M, Darvasi A, Lencz T, Malhotra AK, Rujescu D, Giegling I, Werge T, Hansen T, Ingason A, Nöethen MM, Rietschel M, Cichon S, Djurovic S, Andreassen OA, Cantor RM, Ophoff R, Corvin A, Morris DW, Gill M, Pato CN, Pato MT, Macedo A, Gurling HM, McQuillin A, Pimm J, Hultman C, Lichtenstein P, Sklar P, Purcell SM, Scolnick E, St Clair D, Blackwood DH, Kendler KS. GWA study data mining and independent replication identify cardiomyopathy-associated 5 (CMYA5) as a risk gene for schizophrenia. Mol Psychiatry. 2011 Nov; 16(11):1117-29.
    View in: PubMed
  8. Liu Y, Blackwood DH, Caesar S, de Geus EJ, Farmer A, Ferreira MA, Ferrier IN, Fraser C, Gordon-Smith K, Green EK, Grozeva D, Gurling HM, Hamshere ML, Heutink P, Holmans PA, Hoogendijk WJ, Hottenga JJ, Jones L, Jones IR, Kirov G, Lin D, McGuffin P, Moskvina V, Nolen WA, Perlis RH, Posthuma D, Scolnick EM, Smit AB, Smit JH, Smoller JW, St Clair D, van Dyck R, Verhage M, Willemsen G, Young AH, Zandbelt T, Boomsma DI, Craddock N, O'Donovan MC, Owen MJ, Penninx BW, Purcell S, Sklar P, Sullivan PF. Meta-analysis of genome-wide association data of bipolar disorder and major depressive disorder. Mol Psychiatry. 2011 Jan; 16(1):2-4.
    View in: PubMed
  9. Akil H, Brenner S, Kandel E, Kendler KS, King MC, Scolnick E, Watson JD, Zoghbi HY. Medicine. The future of psychiatric research: genomes and neural circuits. Science. 2010 Mar 26; 327(5973):1580-1.
    View in: PubMed
  10. Nyegaard M, Severinsen JE, Als TD, Hedemand A, Straarup S, Nordentoft M, McQuillin A, Bass N, Lawrence J, Thirumalai S, Pereira AC, Kandaswamy R, Lydall GJ, Sklar P, Scolnick E, Purcell S, Curtis D, Gurling HM, Mortensen PB, Mors O, Børglum AD. Support of association between BRD1 and both schizophrenia and bipolar affective disorder. Am J Med Genet B Neuropsychiatr Genet. 2010 Mar 5; 153B(2):582-91.
    View in: PubMed
  11. Raychaudhuri S, Plenge RM, Rossin EJ, Ng AC, Purcell SM, Sklar P, Scolnick EM, Xavier RJ, Altshuler D, Daly MJ. Identifying relationships among genomic disease regions: predicting genes at pathogenic SNP associations and rare deletions. PLoS Genet. 2009 Jun; 5(6):e1000534.
    View in: PubMed
  12. Perlis RH, Smoller JW, Ferreira MA, McQuillin A, Bass N, Lawrence J, Sachs GS, Nimgaonkar V, Scolnick EM, Gurling H, Sklar P, Purcell S. A genomewide association study of response to lithium for prevention of recurrence in bipolar disorder. Am J Psychiatry. 2009 Jun; 166(6):718-25.
    View in: PubMed
  13. Ferreira MA, O'Donovan MC, Meng YA, Jones IR, Ruderfer DM, Jones L, Fan J, Kirov G, Perlis RH, Green EK, Smoller JW, Grozeva D, Stone J, Nikolov I, Chambert K, Hamshere ML, Nimgaonkar VL, Moskvina V, Thase ME, Caesar S, Sachs GS, Franklin J, Gordon-Smith K, Ardlie KG, Gabriel SB, Fraser C, Blumenstiel B, Defelice M, Breen G, Gill M, Morris DW, Elkin A, Muir WJ, McGhee KA, Williamson R, MacIntyre DJ, MacLean AW, St CD, Robinson M, Van Beck M, Pereira AC, Kandaswamy R, McQuillin A, Collier DA, Bass NJ, Young AH, Lawrence J, Ferrier IN, Anjorin A, Farmer A, Curtis D, Scolnick EM, McGuffin P, Daly MJ, Corvin AP, Holmans PA, Blackwood DH, Gurling HM, Owen MJ, Purcell SM, Sklar P, Craddock N. Collaborative genome-wide association analysis supports a role for ANK3 and CACNA1C in bipolar disorder. Nat Genet. 2008 Sep; 40(9):1056-8.
    View in: PubMed
  14. Sklar P, Smoller JW, Fan J, Ferreira MA, Perlis RH, Chambert K, Nimgaonkar VL, McQueen MB, Faraone SV, Kirby A, de Bakker PI, Ogdie MN, Thase ME, Sachs GS, Todd-Brown K, Gabriel SB, Sougnez C, Gates C, Blumenstiel B, Defelice M, Ardlie KG, Franklin J, Muir WJ, McGhee KA, MacIntyre DJ, McLean A, VanBeck M, McQuillin A, Bass NJ, Robinson M, Lawrence J, Anjorin A, Curtis D, Scolnick EM, Daly MJ, Blackwood DH, Gurling HM, Purcell SM. Whole-genome association study of bipolar disorder. Mol Psychiatry. 2008 Jun; 13(6):558-69.
    View in: PubMed
  15. Mutsuddi M, Morris DW, Waggoner SG, Daly MJ, Scolnick EM, Sklar P. Analysis of high-resolution HapMap of DTNBP1 (Dysbindin) suggests no consistency between reported common variant associations and schizophrenia. Am J Hum Genet. 2006 Nov; 79(5):903-9.
    View in: PubMed
  16. Lichtenstein P, Björk C, Hultman CM, Scolnick E, Sklar P, Sullivan PF. Recurrence risks for schizophrenia in a Swedish national cohort. Psychol Med. 2006 Oct; 36(10):1417-25.
    View in: PubMed
  17. Brandish PE, Chiu CS, Schneeweis J, Brandon NJ, Leech CL, Kornienko O, Scolnick EM, Strulovici B, Zheng W. A cell-based ultra-high-throughput screening assay for identifying inhibitors of D-amino acid oxidase. J Biomol Screen. 2006 Aug; 11(5):481-7.
    View in: PubMed
  18. Scolnick EM. Mechanisms of action of medicines for schizophrenia and bipolar illness: status and limitations. Biol Psychiatry. 2006 Jun 1; 59(11):1039-45.
    View in: PubMed
  19. Scolnick EM, Petryshen T, Sklar P. Schizophrenia: do the genetics and neurobiology of neuregulin provide a pathogenesis model? Harv Rev Psychiatry. 2006 Mar-Apr; 14(2):64-77.
    View in: PubMed
  20. Insel TR, Scolnick EM. Cure therapeutics and strategic prevention: raising the bar for mental health research. Mol Psychiatry. 2006 Jan; 11(1):11-7.
    View in: PubMed
  21. Xiong Y, Wiltsie J, Woods A, Guo J, Pivnichny JV, Tang W, Bansal A, Cummings RT, Cunningham BR, Friedlander AM, Douglas CM, Salowe SP, Zaller DM, Scolnick EM, Schmatz DM, Bartizal K, Hermes JD, MacCoss M, Chapman KT. The discovery of a potent and selective lethal factor inhibitor for adjunct therapy of anthrax infection. Bioorg Med Chem Lett. 2006 Feb 15; 16(4):964-8.
    View in: PubMed
  22. Shoop WL, Xiong Y, Wiltsie J, Woods A, Guo J, Pivnichny JV, Felcetto T, Michael BF, Bansal A, Cummings RT, Cunningham BR, Friedlander AM, Douglas CM, Patel SB, Wisniewski D, Scapin G, Salowe SP, Zaller DM, Chapman KT, Scolnick EM, Schmatz DM, Bartizal K, MacCoss M, Hermes JD. Anthrax lethal factor inhibition. Proc Natl Acad Sci U S A. 2005 May 31; 102(22):7958-63.
    View in: PubMed
  23. Brandish PE, Su M, Holder DJ, Hodor P, Szumiloski J, Kleinhanz RR, Forbes JE, McWhorter ME, Duenwald SJ, Parrish ML, Na S, Liu Y, Phillips RL, Renger JJ, Sankaranarayanan S, Simon AJ, Scolnick EM. Regulation of gene expression by lithium and depletion of inositol in slices of adult rat cortex. Neuron. 2005 Mar 24; 45(6):861-72.
    View in: PubMed
  24. Scolnick E. Program to improve cognitive functioning in patients with schizophrenia: reflections. Schizophr Res. 2004 Dec 15; 72(1):75-7.
    View in: PubMed
  25. Zheng W, Brandish PE, Kolodin DG, Scolnick EM, Strulovici B. High-throughput cell-based screening using scintillation proximity assay for the discovery of inositol phosphatase inhibitors. J Biomol Screen. 2004 Mar; 9(2):132-40.
    View in: PubMed
  26. Sur C, Mallorga PJ, Wittmann M, Jacobson MA, Pascarella D, Williams JB, Brandish PE, Pettibone DJ, Scolnick EM, Conn PJ. N-desmethylclozapine, an allosteric agonist at muscarinic 1 receptor, potentiates N-methyl-D-aspartate receptor activity. Proc Natl Acad Sci U S A. 2003 Nov 11; 100(23):13674-9.
    View in: PubMed
  27. Charney DS, Reynolds CF, Lewis L, Lebowitz BD, Sunderland T, Alexopoulos GS, Blazer DG, Katz IR, Meyers BS, Arean PA, Borson S, Brown C, Bruce ML, Callahan CM, Charlson ME, Conwell Y, Cuthbert BN, Devanand DP, Gibson MJ, Gottlieb GL, Krishnan KR, Laden SK, Lyketsos CG, Mulsant BH, Niederehe G, Olin JT, Oslin DW, Pearson J, Persky T, Pollock BG, Raetzman S, Reynolds M, Salzman C, Schulz R, Schwenk TL, Scolnick E, Unutzer J, Weissman MM, Young RC. Depression and Bipolar Support Alliance consensus statement on the unmet needs in diagnosis and treatment of mood disorders in late life. Arch Gen Psychiatry. 2003 Jul; 60(7):664-72.
    View in: PubMed
  28. Brandish PE, Hill LA, Zheng W, Scolnick EM. Scintillation proximity assay of inositol phosphates in cell extracts: high-throughput measurement of G-protein-coupled receptor activation. Anal Biochem. 2003 Feb 15; 313(2):311-8.
    View in: PubMed
  29. Tamminga CA, Nemeroff CB, Blakely RD, Brady L, Carter CS, Davis KL, Dingledine R, Gorman JM, Grigoriadis DE, Henderson DC, B Innis RB, Killen J, Laughren TP, McDonald WM, M Murphy GM, Paul SM, Rudorfer MV, Sausville E, Schatzberg AF, Scolnick EM, Suppes T. Developing novel treatments for mood disorders: accelerating discovery. Biol Psychiatry. 2002 Sep 15; 52(6):589-609.
    View in: PubMed
  30. Scolnick EM. Discovery and development of antidepressants: a perspective from a pharmaceutical discovery company. Biol Psychiatry. 2002 Aug 1; 52(3):154-6.
    View in: PubMed
  31. Cummings RT, Salowe SP, Cunningham BR, Wiltsie J, Park YW, Sonatore LM, Wisniewski D, Douglas CM, Hermes JD, Scolnick EM. A peptide-based fluorescence resonance energy transfer assay for Bacillus anthracis lethal factor protease. Proc Natl Acad Sci U S A. 2002 May 14; 99(10):6603-6.
    View in: PubMed
  32. Scolnick EM, Slater EE, Williams GW. "Natural history" clinical trials: an enduring contribution to modern medical practice. Adv Protein Chem. 2001; 56:1-12.
    View in: PubMed
  33. Kramer MS, Cutler N, Feighner J, Shrivastava R, Carman J, Sramek JJ, Reines SA, Liu G, Snavely D, Wyatt-Knowles E, Hale JJ, Mills SG, MacCoss M, Swain CJ, Harrison T, Hill RG, Hefti F, Scolnick EM, Cascieri MA, Chicchi GG, Sadowski S, Williams AR, Hewson L, Smith D, Carlson EJ, Hargreaves RJ, Rupniak NM. Distinct mechanism for antidepressant activity by blockade of central substance P receptors. Science. 1998 Sep 11; 281(5383):1640-5.
    View in: PubMed
  34. Kohl NE, Mosser SD, deSolms SJ, Giuliani EA, Pompliano DL, Graham SL, Smith RL, Scolnick EM, Oliff A, Gibbs JB. Selective inhibition of ras-dependent transformation by a farnesyltransferase inhibitor. Science. 1993 Jun 25; 260(5116):1934-7.
    View in: PubMed
  35. Gibbs JB, Pompliano DL, Mosser SD, Rands E, Lingham RB, Singh SB, Scolnick EM, Kohl NE, Oliff A. Selective inhibition of farnesyl-protein transferase blocks ras processing in vivo. J Biol Chem. 1993 Apr 15; 268(11):7617-20.
    View in: PubMed
  36. Marshall MS, Davis LJ, Keys RD, Mosser SD, Hill WS, Scolnick EM, Gibbs JB. Identification of amino acid residues required for Ras p21 target activation. Mol Cell Biol. 1991 Aug; 11(8):3997-4004.
    View in: PubMed
  37. Scolnick EM. The partnership of academia and industry in pharmacologic research. J Lab Clin Med. 1991 Jan; 117(1):8-14.
    View in: PubMed
  38. Gibbs JB, Marshall MS, Scolnick EM, Dixon RA, Vogel US. Modulation of guanine nucleotides bound to Ras in NIH3T3 cells by oncogenes, growth factors, and the GTPase activating protein (GAP). J Biol Chem. 1990 Nov 25; 265(33):20437-42.
    View in: PubMed
  39. Gibbs JB, Schaber MD, Garsky VM, Vogel US, Scolnick EM, Dixon RA, Marshall MS. Structure/function relationships of ras and guanosine triphosphatase-activating protein. Soc Gen Physiol Ser. 1990; 45:77-85.
    View in: PubMed
  40. Gibbs JB, Schaber MD, Schofield TL, Scolnick EM, Sigal IS. Xenopus oocyte germinal-vesicle breakdown induced by [Val12]Ras is inhibited by a cytosol-localized Ras mutant. Proc Natl Acad Sci U S A. 1989 Sep; 86(17):6630-4.
    View in: PubMed
  41. Marshall MS, Hill WS, Ng AS, Vogel US, Schaber MD, Scolnick EM, Dixon RA, Sigal IS, Gibbs JB. A C-terminal domain of GAP is sufficient to stimulate ras p21 GTPase activity. EMBO J. 1989 Apr; 8(4):1105-10.
    View in: PubMed
  42. Schaber MD, Garsky VM, Boylan D, Hill WS, Scolnick EM, Marshall MS, Sigal IS, Gibbs JB. Ras interaction with the GTPase-activating protein (GAP). Proteins. 1989; 6(3):306-15.
    View in: PubMed
  43. Vogel US, Dixon RA, Schaber MD, Diehl RE, Marshall MS, Scolnick EM, Sigal IS, Gibbs JB. Cloning of bovine GAP and its interaction with oncogenic ras p21. Nature. 1988 Sep 1; 335(6185):90-3.
    View in: PubMed
  44. Kohl NE, Emini EA, Schleif WA, Davis LJ, Heimbach JC, Dixon RA, Scolnick EM, Sigal IS. Active human immunodeficiency virus protease is required for viral infectivity. Proc Natl Acad Sci U S A. 1988 Jul; 85(13):4686-90.
    View in: PubMed
  45. Gibbs JB, Schaber MD, Allard WJ, Sigal IS, Scolnick EM. Purification of ras GTPase activating protein from bovine brain. Proc Natl Acad Sci U S A. 1988 Jul; 85(14):5026-30.
    View in: PubMed
  46. Gibbs JB, Marsico-Ahern JD, Scolnick EM, Sigal IS. Inhibition of yeast adenylate cyclase by antibodies to ras p21. Biochem J. 1988 May 15; 252(1):289-92.
    View in: PubMed
  47. Sigal IS, Marshall MS, Schaber MD, Vogel US, Scolnick EM, Gibbs JB. Structure/function studies of the ras protein. Cold Spring Harb Symp Quant Biol. 1988; 53 Pt 2:863-9.
    View in: PubMed
  48. Sigal IS, D'Alonzo JS, Ahern JD, Marshall MS, Smith GM, Scolnick EM, Gibbs JB. The ras oncogene protein as a G-protein. Adv Second Messenger Phosphoprotein Res. 1988; 21:193-200.
    View in: PubMed
  49. Marshall MS, Gibbs JB, Scolnick EM, Sigal IS. An adenylate cyclase from Saccharomyces cerevisiae that is stimulated by RAS proteins with effector mutations. Mol Cell Biol. 1988 Jan; 8(1):52-61.
    View in: PubMed
  50. Sigal IS, Smith GM, Jurnak F, Marsico-Ahern JD, D'Alonzo JS, Scolnick EM, Gibbs JB. Molecular approaches towards an anti-ras drug. Anticancer Drug Des. 1987 Oct; 2(2):107-15.
    View in: PubMed
  51. Gibbs JB, Schaber MD, Marshall MS, Scolnick EM, Sigal IS. Identification of guanine nucleotides bound to ras-encoded proteins in growing yeast cells. J Biol Chem. 1987 Aug 5; 262(22):10426-9.
    View in: PubMed
  52. Marshall MS, Gibbs JB, Scolnick EM, Sigal IS. Regulatory function of the Saccharomyces cerevisiae RAS C-terminus. Mol Cell Biol. 1987 Jul; 7(7):2309-15.
    View in: PubMed
  53. Stein RB, Tai JY, Scolnick EM. Molecular cloning of the temperature-sensitive 371 Kirsten murine sarcoma virus and expression in Escherichia coli of the mutant and wild-type viral Kirsten ras p21 proteins. J Virol. 1986 Nov; 60(2):782-6.
    View in: PubMed
  54. Provost PJ, Bishop RP, Gerety RJ, Hilleman MR, McAleer WJ, Scolnick EM, Stevens CE. New findings in live, attenuated hepatitis A vaccine development. J Med Virol. 1986 Oct; 20(2):165-75.
    View in: PubMed
  55. Emini EA, Ellis RW, Miller WJ, McAleer WJ, Scolnick EM, Gerety RJ. Production and immunological analysis of recombinant hepatitis B vaccine. J Infect. 1986 Jul; 13 Suppl A:3-9.
    View in: PubMed
  56. Zajac BA, West DJ, McAleer WJ, Scolnick EM. Overview of clinical studies with hepatitis B vaccine made by recombinant DNA. J Infect. 1986 Jul; 13 Suppl A:39-45.
    View in: PubMed
  57. Sigal IS, Gibbs JB, D'Alonzo JS, Scolnick EM. Identification of effector residues and a neutralizing epitope of Ha-ras-encoded p21. Proc Natl Acad Sci U S A. 1986 Jul; 83(13):4725-9.
    View in: PubMed
  58. Ruta M, Wolford R, Dhar R, Defeo-Jones D, Ellis RW, Scolnick EM. Nucleotide sequence of the two rat cellular rasH genes. Mol Cell Biol. 1986 May; 6(5):1706-10.
    View in: PubMed
  59. Sigal IS, Gibbs JB, D'Alonzo JS, Temeles GL, Wolanski BS, Socher SH, Scolnick EM. Mutant ras-encoded proteins with altered nucleotide binding exert dominant biological effects. Proc Natl Acad Sci U S A. 1986 Feb; 83(4):952-6.
    View in: PubMed
  60. Weibel RE, Kuter BJ, Neff BJ, Rothenberger CA, Fitzgerald AJ, Connor KA, Morton D, McLean AA, Scolnick EM. Live Oka/Merck varicella vaccine in healthy children. Further clinical and laboratory assessment. JAMA. 1985 Nov 1; 254(17):2435-9.
    View in: PubMed
  61. Wampler DE, Lehman ED, Boger J, McAleer WJ, Scolnick EM. Multiple chemical forms of hepatitis B surface antigen produced in yeast. Proc Natl Acad Sci U S A. 1985 Oct; 82(20):6830-4.
    View in: PubMed
  62. Tolman RL, Field AK, Karkas JD, Wagner AF, Germershausen J, Crumpacker C, Scolnick EM. 2'-Nor-cGMP: a seco-cyclic nucleotide with powerful anti-DNA-viral activity. Biochem Biophys Res Commun. 1985 May 16; 128(3):1329-35.
    View in: PubMed
  63. Weeks MO, Hager GL, Lowe R, Scolnick EM. Development and analysis of a transformation-defective mutant of Harvey murine sarcoma tk virus and its gene product. J Virol. 1985 May; 54(2):586-97.
    View in: PubMed
  64. DeFeo-Jones D, Tatchell K, Robinson LC, Sigal IS, Vass WC, Lowy DR, Scolnick EM. Mammalian and yeast ras gene products: biological function in their heterologous systems. Science. 1985 Apr 12; 228(4696):179-84.
    View in: PubMed
  65. Poe M, Scolnick EM, Stein RB. Viral Harvey ras p21 expressed in Escherichia coli purifies as a binary one-to-one complex with GDP. J Biol Chem. 1985 Apr 10; 260(7):3906-9.
    View in: PubMed
  66. Hyland JK, Rogers CM, Scolnick EM, Stein RB, Ellis R, Baserga R. Microinjected ras family oncogenes stimulate DNA synthesis in quiescent mammalian cells. Virology. 1985 Mar; 141(2):333-6.
    View in: PubMed
  67. Temeles GL, Gibbs JB, D'Alonzo JS, Sigal IS, Scolnick EM. Yeast and mammalian ras proteins have conserved biochemical properties. Nature. 1985 Feb 21-27; 313(6004):700-3.
    View in: PubMed
  68. Hughes JV, Stanton LW, Tomassini JE, Long WJ, Scolnick EM. Neutralizing monoclonal antibodies to hepatitis A virus: partial localization of a neutralizing antigenic site. J Virol. 1984 Nov; 52(2):465-73.
    View in: PubMed
  69. Temeles GL, DeFeo-Jones D, Tatchell K, Ellinger MS, Scolnick EM. Expression and characterization of ras mRNAs from Saccharomyces cerevisiae. Mol Cell Biol. 1984 Nov; 4(11):2298-305.
    View in: PubMed
  70. Gibbs JB, Sigal IS, Poe M, Scolnick EM. Intrinsic GTPase activity distinguishes normal and oncogenic ras p21 molecules. Proc Natl Acad Sci U S A. 1984 Sep; 81(18):5704-8.
    View in: PubMed
  71. Gonda MA, Kaminchick J, Oliff A, Menke J, Nagashima K, Scolnick EM. Heteroduplex analysis of molecular clones of the pathogenic Friend virus complex: Friend murine leukemia virus, Friend mink cell focus-forming virus, and the polycythemia- and anemia-inducing strains of Friend spleen focus-forming virus. J Virol. 1984 Aug; 51(2):306-14.
    View in: PubMed
  72. Scolnick EM, McLean AA, West DJ, McAleer WJ, Miller WJ, Buynak EB. Clinical evaluation in healthy adults of a hepatitis B vaccine made by recombinant DNA. JAMA. 1984 Jun 1; 251(21):2812-5.
    View in: PubMed
  73. Tatchell K, Chaleff DT, DeFeo-Jones D, Scolnick EM. Requirement of either of a pair of ras-related genes of Saccharomyces cerevisiae for spore viability. Nature. 1984 Jun 7-13; 309(5968):523-7.
    View in: PubMed
  74. Sakaguchi AY, Zabel BU, Grzeschik KH, Law ML, Ellis RW, Scolnick EM, Naylor SL. Regional localization of two human cellular Kirsten ras genes on chromosomes 6 and 12. Mol Cell Biol. 1984 May; 4(5):989-93.
    View in: PubMed
  75. Stein RB, Robinson PS, Scolnick EM. Photoaffinity labeling with GTP of viral p21 ras protein expressed in Escherichia coli. J Virol. 1984 May; 50(2):343-51.
    View in: PubMed
  76. Gibbs JB, Ellis RW, Scolnick EM. Autophosphorylation of v-Ha-ras p21 is modulated by amino acid residue 12. Proc Natl Acad Sci U S A. 1984 May; 81(9):2674-8.
    View in: PubMed
  77. Dhar R, Nieto A, Koller R, DeFeo-Jones D, Scolnick EM. Nucleotide sequence of two rasH related-genes isolated from the yeast Saccharomyces cerevisiae. Nucleic Acids Res. 1984 Apr 25; 12(8):3611-8.
    View in: PubMed
  78. Provost PJ, Giesa PA, Buynak EB, McLean AA, Scolnick EM. Fetal rhesus kidney cells used for hepatitis A viral vaccine development are free from polyomavirus. Lancet. 1984 Feb 18; 1(8373):395.
    View in: PubMed
  79. Willumsen BM, Ellis RW, Scolnick EM, Lowy DR. Further genetic localization of the transforming sequences of the p21 v-ras gene of Harvey murine sarcoma virus. J Virol. 1984 Feb; 49(2):601-3.
    View in: PubMed
  80. Sakaguchi AY, Lalley PA, Zabel BU, Ellis RW, Scolnick EM, Naylor SL. Chromosome assignments of four mouse cellular homologs of sarcoma and leukemia virus oncogenes. Proc Natl Acad Sci U S A. 1984 Jan; 81(2):525-9.
    View in: PubMed
  81. Papageorge AG, Defeo-Jones D, Robinson P, Temeles G, Scolnick EM. Saccharomyces cerevisiae synthesizes proteins related to the p21 gene product of ras genes found in mammals. Mol Cell Biol. 1984 Jan; 4(1):23-9.
    View in: PubMed
  82. DeFeo-Jones D, Scolnick EM, Koller R, Dhar R. ras-Related gene sequences identified and isolated from Saccharomyces cerevisiae. Nature. 1983 Dec 15-21; 306(5944):707-9.
    View in: PubMed
  83. Yuspa SH, Vass W, Scolnick E. Altered growth and differentiation of cultured mouse epidermal cells infected with oncogenic retrovirus: contrasting effects of viruses and chemicals. Cancer Res. 1983 Dec; 43(12 Pt 1):6021-30.
    View in: PubMed
  84. Cooper JA, Scolnick EM, Ozanne B, Hunter T. Epidermal growth factor receptor metabolism and protein kinase activity in human A431 cells infected with Snyder-Theilen feline sarcoma virus or harvey or Kirsten murine sarcoma virus. J Virol. 1983 Dec; 48(3):752-64.
    View in: PubMed
  85. Pravtcheva DD, Ruddle FH, Ellis RW, Scolnick EM. Assignment of murine cellular Harvey ras gene to chromosome 7. Somatic Cell Genet. 1983 Nov; 9(6):681-6.
    View in: PubMed
  86. Noda M, Selinger Z, Scolnick EM, Bassin RH. Flat revertants isolated from Kirsten sarcoma virus-transformed cells are resistant to the action of specific oncogenes. Proc Natl Acad Sci U S A. 1983 Sep; 80(18):5602-6.
    View in: PubMed
  87. Wolff L, Scolnick E, Ruscetti S. Envelope gene of the Friend spleen focus-forming virus: deletion and insertions in 3' gp70/p15E-encoding region have resulted in unique features in the primary structure of its protein product. Proc Natl Acad Sci U S A. 1983 Aug; 80(15):4718-22.
    View in: PubMed
  88. Ruscetti SK, Scolnick EM. Expression of a transformation-related protein (p53) in the malignant stage of Friend virus-induced diseases. J Virol. 1983 Jun; 46(3):1022-6.
    View in: PubMed
  89. Anderson SM, Scolnick EM. Construction and isolation of a transforming murine retrovirus containing the src gene of Rous sarcoma virus. J Virol. 1983 May; 46(2):594-605.
    View in: PubMed
  90. Bestwick R, Ruta M, Kiessling A, Faust C, Linemeyer D, Scolnick E, Kabat D. Genetic structure of Rauscher spleen focus-forming virus. J Virol. 1983 Mar; 45(3):1217-22.
    View in: PubMed
  91. Ellis RW, DeFeo D, Papageorge A, Scolnick EM. Expression of endogenous p21 ras genes. Prog Clin Biol Res. 1983; 119:67-77.
    View in: PubMed
  92. Kaminchik J, Hankins WD, Ruscetti SK, Linemeyer DL, Scolnick EM. Molecular cloning of biologically active proviral DNA of the anemia-inducing strain of spleen focus-forming virus. J Virol. 1982 Dec; 44(3):922-31.
    View in: PubMed
  93. Sefton BM, Trowbridge IS, Cooper JA, Scolnick EM. The transforming proteins of Rous sarcoma virus, Harvey sarcoma virus and Abelson virus contain tightly bound lipid. Cell. 1982 Dec; 31(2 Pt 1):465-74.
    View in: PubMed
  94. Tabin CJ, Bradley SM, Bargmann CI, Weinberg RA, Papageorge AG, Scolnick EM, Dhar R, Lowy DR, Chang EH. Mechanism of activation of a human oncogene. Nature. 1982 Nov 11; 300(5888):143-9.
    View in: PubMed
  95. Papageorge A, Lowy D, Scolnick EM. Comparative biochemical properties of p21 ras molecules coded for by viral and cellular ras genes. J Virol. 1982 Nov; 44(2):509-19.
    View in: PubMed
  96. Ellis RW, DeFeo D, Furth ME, Scolnick EM. Mouse cells contain two distinct ras gene mRNA species that can be translated into a p21 onc protein. Mol Cell Biol. 1982 Nov; 2(11):1339-45.
    View in: PubMed
  97. Dhar R, Ellis RW, Shih TY, Oroszlan S, Shapiro B, Maizel J, Lowy D, Scolnick E. Nucleotide sequence of the p21 transforming protein of Harvey murine sarcoma virus. Science. 1982 Sep 3; 217(4563):934-6.
    View in: PubMed
  98. Chang EH, Gonda MA, Ellis RW, Scolnick EM, Lowy DR. Human genome contains four genes homologous to transforming genes of Harvey and Kirsten murine sarcoma viruses. Proc Natl Acad Sci U S A. 1982 Aug; 79(16):4848-52.
    View in: PubMed
  99. Furth ME, Davis LJ, Fleurdelys B, Scolnick EM. Monoclonal antibodies to the p21 products of the transforming gene of Harvey murine sarcoma virus and of the cellular ras gene family. J Virol. 1982 Jul; 43(1):294-304.
    View in: PubMed
  100. Linemeyer DL, Menke JG, Ruscetti SK, Evans LH, Scolnick EM. Envelope gene sequences which encode the gp52 protein of spleen focus-forming virus are required for the induction of erythroid cell proliferation. J Virol. 1982 Jul; 43(1):223-33.
    View in: PubMed
  101. Scolnick EM. Hyperplastic and neoplastic erythroproliferative diseases induced by oncogenic murine retroviruses. Biochim Biophys Acta. 1982 Jun 28; 651(4):273-83.
    View in: PubMed
  102. Chang EH, Furth ME, Scolnick EM, Lowy DR. Tumorigenic transformation of mammalian cells induced by a normal human gene homologous to the oncogene of Harvey murine sarcoma virus. Nature. 1982 Jun 10; 297(5866):479-83.
    View in: PubMed
  103. Shih TY, Weeks MO, Gruss P, Dhar R, Oroszlan S, Scolnick EM. Identification of a precursor in the biosynthesis of the p21 transforming protein of harvey murine sarcoma virus. J Virol. 1982 Apr; 42(1):253-61.
    View in: PubMed
  104. Chattopadhyay SK, Chang EH, Lander MR, Ellis RW, Scolnick EM, Lowy DR. Amplification and rearrangement of onc genes in mammalian species. Nature. 1982 Mar 25; 296(5855):361-3.
    View in: PubMed
  105. Ruscetti SK, Feild JA, Scolnick EM. Polycythaemia- and anaemia-inducing strains of spleen focus-forming virus differ in post-translational processing of envelope-related glycoproteins. Nature. 1981 Dec 17; 294(5842):663-5.
    View in: PubMed
  106. Coffin JM, Varmus HE, Bishop JM, Essex M, Hardy WD, Martin GS, Rosenberg NE, Scolnick EM, Weinberg RA, Vogt PK. Proposal for naming host cell-derived inserts in retrovirus genomes. J Virol. 1981 Dec; 40(3):953-7.
    View in: PubMed
  107. Gruss P, Ellis RW, Shih TY, König M, Scolnick EM, Khoury G. SV40 recombinant molecules express the gene encoding p21 transforming protein of Harvey murine sarcoma virus. Nature. 1981 Oct 8; 293(5832):486-8.
    View in: PubMed
  108. Dexter TM, Testa NG, Allen TD, Rutherford T, Scolnick E. Molecular and cell biologic aspects of erythropoiesis in long-term bone marrow cultures. Blood. 1981 Oct; 58(4):699-707.
    View in: PubMed
  109. Andersen PR, Devare SG, Tronick SR, Ellis RW, Aaronson SA, Scolnick EM. Generation of BALB-MuSV and Ha-MuSC by type C virus transduction of homologous transforming genes from different species. Cell. 1981 Oct; 26(1 Pt 1):129-34.
    View in: PubMed
  110. Hankins WD, Scolnick EM. Harvey and Kirsten sarcoma viruses promote the growth and differentiation of erythroid precursor cells in vitro. Cell. 1981 Oct; 26(1 Pt 1):91-7.
    View in: PubMed
  111. Wei CM, Gibson M, Spear PG, Scolnick EM. Construction and isolation of a transmissible retrovirus containing the src gene of Harvey murine sarcoma virus and the thymidine kinase gene of herpes simplex virus type 1. J Virol. 1981 Sep; 39(3):935-44.
    View in: PubMed
  112. Dexter TM, Allen TD, Testa NG, Scolnick E. Friend disease in vitro. J Exp Med. 1981 Sep 1; 154(3):594-608.
    View in: PubMed
  113. Ellis RW, Defeo D, Shih TY, Gonda MA, Young HA, Tsuchida N, Lowy DR, Scolnick EM. The p21 src genes of Harvey and Kirsten sarcoma viruses originate from divergent members of a family of normal vertebrate genes. Nature. 1981 Aug 6; 292(5823):506-11.
    View in: PubMed
  114. Oliff A, Ruscetti S, Douglass EC, Scolnick E. Isolation of transplantable erythroleukemia cells from mice infected with helper-independent Friend murine leukemia virus. Blood. 1981 Aug; 58(2):244-54.
    View in: PubMed
  115. DeFeo D, Gonda MA, Young HA, Chang EH, Lowy DR, Scolnick EM, Ellis RW. Analysis of two divergent rat genomic clones homologous to the transforming gene of Harvey murine sarcoma virus. Proc Natl Acad Sci U S A. 1981 Jun; 78(6):3328-32.
    View in: PubMed
  116. Linemeyer DL, Ruscetti SK, Scolnick EM, Evans LH, Duesberg PH. Biological activity of the spleen focus-forming virus is encoded by a molecularly cloned subgenomic fragment of spleen focus-forming virus DNA. Proc Natl Acad Sci U S A. 1981 Mar; 78(3):1401-5.
    View in: PubMed
  117. Scolnick EM. Transformation by rat-derived oncogenic retroviruses. Microbiol Rev. 1981 Mar; 45(1):1-8.
    View in: PubMed
  118. Evans LH, Duesberg PH, Linemeyer DL, Ruscetti SK, Scolnick EM. Structural and functional studies of the Friend spleen focus-forming virus: structural relationship of SFFV to dualtropic viruses and molecular cloning of a biologically active subgenomic fragment of SFFV DNA. Haematol Blood Transfus. 1981; 26:472-8.
    View in: PubMed
  119. Scolnick EM, Weeks MO, Shih TY, Ruscetti SK, Dexter TM. Markedly elevated levels of an endogenous sarc protein in a hemopoietic precursor cell line. Mol Cell Biol. 1981 Jan; 1(1):66-74.
    View in: PubMed
  120. Chang EH, Ellis RW, Scolnick EM, Lowy DR. Transformation by cloned Harvey murine sarcoma virus DNA: efficiency increased by long terminal repeat DNA. Science. 1980 Dec 12; 210(4475):1249-51.
    View in: PubMed
  121. Schultz AM, Ruscetti SK, Scolnick EM, Oroszlan S. The env-gene of the spleen focus-forming virus lacks expression of p15(E) determinants. Virology. 1980 Dec; 107(2):537-42.
    View in: PubMed
  122. Ellis RW, DeFeo D, Maryak JM, Young HA, Shih TY, Chang EH, Lowy DR, Scolnick EM. Dual evolutionary origin for the rat genetic sequences of Harvey murine sarcoma virus. J Virol. 1980 Nov; 36(2):408-20.
    View in: PubMed
  123. Young HA, Gonda MA, De Feo D, Ellis RW, Nagashima K, Scolnick EM. Heteroduplex analysis of cloned rat endogenous replication-defective (30 S) retrovirus and Harvey murine sarcoma virus. Virology. 1980 Nov; 107(1):89-99.
    View in: PubMed
  124. Langbeheim H, Shih TY, Scolnick EM. Identification of a normal vertebrate cell protein related to the p21 src of Harvey murine sarcoma virus. Virology. 1980 Oct 30; 106(2):292-300.
    View in: PubMed
  125. Shih TY, Papageorge AG, Stokes PE, Weeks MO, Scolnick EM. Guanine nucleotide-binding and autophosphorylating activities associated with the p21src protein of Harvey murine sarcoma virus. Nature. 1980 Oct 23; 287(5784):686-91.
    View in: PubMed
  126. Dexter TM, Garland J, Scott D, Scolnick E, Metcalf D. Growth of factor-dependent hemopoietic precursor cell lines. J Exp Med. 1980 Oct 1; 152(4):1036-47.
    View in: PubMed
  127. Troxler DH, Ruscetti SK, Scolnick EM. The molecular biology of Friend virus. Biochim Biophys Acta. 1980 Sep 22; 605(3):305-24.
    View in: PubMed
  128. Linemeyer DL, Ruscetti SK, Menke JG, Scolnick EM. Recovery of biologically active spleen focus-forming virus from molecularly cloned spleen focus-forming virus-pBR322 circular DNA by cotransfection with infectious type C retroviral DNA. J Virol. 1980 Sep; 35(3):710-21.
    View in: PubMed
  129. Oliff A, Linemeyer D, Ruscetti S, Lowe R, Lowy DR, Scolnick E. Subgenomic fragment of molecular cloned Friend murine leukemia virus DNA contains the gene(s) responsible for Friend murine leukemia virus-induced disease. J Virol. 1980 Sep; 35(3):924-36.
    View in: PubMed
  130. Wei CM, Lowy DR, Scolnick EM. Mapping of transforming region of the Harvey murine sarcoma virus genome by using insertion-deletion mutants constructed in vitro. Proc Natl Acad Sci U S A. 1980 Aug; 77(8):4674-8.
    View in: PubMed
  131. Chang EH, Maryak JM, Wei CM, Shih TY, Shober R, Cheung HL, Ellis RW, Hager GL, Scolnick EM, Lowy DR. Functional organization of the Harvey murine sarcoma virus genome. J Virol. 1980 Jul; 35(1):76-92.
    View in: PubMed
  132. Troxler DH, Ruscetti SK, Linemeyer DL, Scolnick EM. Helper-independent and replication-defective erythroblastosis-inducing viruses contained within anemia-inducing Friend virus complex (FV-A). Virology. 1980 Apr 15; 102(1):28-45.
    View in: PubMed
  133. Willingham MC, Pastan I, Shih TY, Scolnick EM. Localization of the src gene product of the Harvey strain of MSV to plasma membrane of transformed cells by electron microscopic immunocytochemistry. Cell. 1980 Apr; 19(4):1005-14.
    View in: PubMed
  134. Evans LH, Duesberg PH, Scolnick EM. Replication of spleen focus-forming Friend virus in fibroblasts from C57BL mice that are genetically resistant to spleen focus formation. Virology. 1980 Mar; 101(2):534-9.
    View in: PubMed
  135. Chang HW, Garon CF, Chang EH, Lowy DR, Hager GL, Scolnick EM, Repaske R, Martin MA. Molecular cloning of the Harvey sarcoma virus circular DNA intermediates. II. Further structural analyses. J Virol. 1980 Feb; 33(2):845-55.
    View in: PubMed
  136. Scolnick EM, Shih TY, Maryak J, Ellis R, Chang E, Lowy D. Guanine nucleotide binding activity of the src gene product of rat-derived murine sarcoma viruses. Ann N Y Acad Sci. 1980; 354:398-409.
    View in: PubMed
  137. Ruscetti S, Troxler D, Linemeyer D, Scolnick E. Three laboratory strains of spleen focus-forming virus: comparison of their genomes and translational products. J Virol. 1980 Jan; 33(1):140-51.
    View in: PubMed
  138. Evans L, Nunn M, Duesberg PH, Troxler D, Scolnick E. RNAs of defective and nondefective components of Friend anemia and polycythemia virus strains identified and compared. Cold Spring Harb Symp Quant Biol. 1980; 44 Pt 2,:823-35.
    View in: PubMed
  139. Oliff AI, Hager GL, Chang EH, Scolnick EM, Chan HW, Lowy DR. Transfection of molecularly cloned Friend murine leukemia virus DNA yields a highly leukemogenic helper-independent type C virus. J Virol. 1980 Jan; 33(1):475-86.
    View in: PubMed
  140. Scolnick EM, Papageorge AG, Shih TY. Guanine nucleotide-binding activity as an assay for src protein of rat-derived murine sarcoma viruses. Proc Natl Acad Sci U S A. 1979 Oct; 76(10):5355-9.
    View in: PubMed
  141. Hager GL, Chang EH, Chan HW, Garon CF, Israel MA, Martin MA, Scolnick EM, Lowy DR. Molecular cloning of the Harvey sarcoma virus closed circular DNA intermediates: initial structural and biological characterization. J Virol. 1979 Sep; 31(3):795-809.
    View in: PubMed
  142. Chien UH, Lai M, Shih TY, Verma IM, Scolnick EM, Roy-Burman P, Davidson N. Heteroduplex analysis of the sequence relationships between the genomes of Kirsten and Harvey sarcoma viruses, their respective parental murine leukemia viruses, and the rat endogenous 30S RNA. J Virol. 1979 Sep; 31(3):752-60.
    View in: PubMed
  143. Shih TY, Weeks MO, Young HA, Scolnick EM. p21 of Kirsten murine sarcoma virus is thermolabile in a viral mutant temperature sensitive for the maintenance of transformation. J Virol. 1979 Aug; 31(2):546-6.
    View in: PubMed
  144. Gillis S, Ruscetti SK, Gillis AE, Troxler DH, Scolnick EM, Smith KA. The spleen focus-forming virus (SFFV)-specific neoantigen shares cross-reactive determinants with mink cell focus-inducing (MCF) virus gp70. Virology. 1979 Jul 30; 96(2):421-8.
    View in: PubMed
  145. Evans LH, Duesberg PH, Troxler DH, Scolnick EM. Spleen focus-forming Friend virus: identification of genomic RNA and its relationship to helper virus RNA. J Virol. 1979 Jul; 31(1):133-46.
    View in: PubMed
  146. Young HA, Shih TY, Scolnick EM, Rasheed S, Gardner MB. Different rat-derived transforming retroviruses code for an immunologically related intracellular phosphoprotein. Proc Natl Acad Sci U S A. 1979 Jul; 76(7):3523-7.
    View in: PubMed
  147. Frankel AE, Gilbert JH, Porzig KJ, Scolnick EM, Aaronson SA. Nature and distribution of feline sarcoma virus nucleotide sequences. J Virol. 1979 Jun; 30(3):821-7.
    View in: PubMed
  148. Ruscetti SK, Linemeyer D, Feild J, Troxler D, Scolnick EM. Characterization of a protein found in cells infected with the spleen focus-forming virus that shares immunological cross-reactivity with the gp70 found in mink cell focus-inducing virus particles. J Virol. 1979 Jun; 30(3):787-98.
    View in: PubMed
  149. Scolnick EM, Vass WC, Howk RS, Duesberg PH. Defective retrovirus-like 30S RNA species of rat and mouse cells are infectious if packaged by type C helper virus. J Virol. 1979 Mar; 29(3):964-72.
    View in: PubMed
  150. Young HA, Wenk ML, Goodman DG, Scolnick EM. Expression of RNA of an endogenous replication-defective retrovirus in rat mammary adenocarcinomas induced by 7,12-dimethylbenz[a]anthracene. J Natl Cancer Inst. 1978 Nov; 61(5):1329-37.
    View in: PubMed
  151. Kuff EL, Lueders KK, Scolnick EM. Nucleotide sequence relationship between intracisternal type A particles of Mus musculus and an endogenous retrovirus (M432) of Mus cervicolor. J Virol. 1978 Oct; 28(1):66-74.
    View in: PubMed
  152. Chien YH, Verma IM, Shih TY, Scolnick EM, Davidson N. Heteroduplex analysis of the sequence relations between the RNAs of mink cell focus-inducing and murine leukemia viruses. J Virol. 1978 Oct; 28(1):352-60.
    View in: PubMed
  153. Troxler DH, Yuan E, Linemeyer D, Ruscetti S, Scolnick EM. Helper-independent mink cell focus-inducing strains of Friend murine type-C virus: potential relationship to the origin of replication-defective spleen focus-forming virus. J Exp Med. 1978 Sep 1; 148(3):639-53.
    View in: PubMed
  154. Ruscetti S, Linemeyer D, Field J, Troxler D, Scolnick E. Type-specific radioimmunoassays for the gp70s of mink cell focus-inducing murine leukemia viruses: expression of a cross-reacting antigen in cells infected with the Friend strain of the spleen focus-forming virus. J Exp Med. 1978 Sep 1; 148(3):654-63.
    View in: PubMed
  155. Barbacid M, Troxler DH, Scolnick EM, Aaronson SA. Analysis of translational products of Friend strain of spleen focus-forming virus. J Virol. 1978 Sep; 27(3):826-30.
    View in: PubMed
  156. Shih TY, Williams DR, Weeks MO, Maryak JM, Vass WC, Scolnick EM. Comparison of the genomic organization of Kirsten and Harvey sarcoma viruses. J Virol. 1978 Jul; 27(1):45-55.
    View in: PubMed
  157. Lowy DR, Rands E, Scolnick EM. Helper-independent transformation by unintegrated Harvey sarcoma virus DNA. J Virol. 1978 May; 26(2):291-8.
    View in: PubMed
  158. Parks WP, Young HA, Scolnick EM. Eukaryotic gene regulation studies with mouse mammary tumor virus in tissue culture cells. Natl Cancer Inst Monogr. 1978 May; (48):215-8.
    View in: PubMed
  159. Shih TY, Weeks MO, Troxler DH, Coffin JM, Scolnick EM. Mapping host range-specific oligonucleotides within genomes of the ecotropic and mink cell focus-inducing strains of Moloney murine leukemia virus. J Virol. 1978 Apr; 26(1):71-83.
    View in: PubMed
  160. Troxler DH, Scolnick EM. Rapid leukemia induced by cloned friend strain of replicating murine type-C virus. Association with induction of xenotropic-related RNA sequences contained in spleen focus-forming virus. Virology. 1978 Mar; 85(1):17-27.
    View in: PubMed
  161. Howk RS, Troxler DH, Lowy D, Duesberg PH, Scolnick EM. Identification of a 30S RNA with properties of a defective type C virus in murine cells. J Virol. 1978 Jan; 25(1):115-23.
    View in: PubMed
  162. Shih TY, Young HA, Coffin JM, Scolnick EM. Physical map of the Kirsten sarcoma virus genome as determined by fingerprinting RNase T1-resistant oligonucleotides. J Virol. 1978 Jan; 25(1):238-52.
    View in: PubMed
  163. Lowy DR, Scolnick EM. Glucocorticoids induce focus formation and increase sarcoma viral expression in a mink cell line that contains a murine sarcoma viral genome. J Virol. 1978 Jan; 25(1):157-63.
    View in: PubMed
  164. Duesberg PH, Scolnick EM. Murine leukemia viruses containing an approximately 30 S RNA subunit of unknown biological activity, in addition to the 38 S subunit of the viral genome. Virology. 1977 Nov; 83(1):211-6.
    View in: PubMed
  165. Troxler DH, Lowy D, Howk R, Young H, Scolnick EM. Friend strain of spleen focus-forming virus is a recombinant between ecotropic murine type C virus and the env gene region of xenotropic type C virus. Proc Natl Acad Sci U S A. 1977 Oct; 74(10):4671-5.
    View in: PubMed
  166. Parks WP, Scolnick EM. In vitro translation of Harvey murine sarcoma virus RNA. J Virol. 1977 Jun; 22(3):711-9.
    View in: PubMed
  167. Shih TY, Young HA, Parks WP, Scolnick EM. In vitro transcription of Moloney leukemia virus genes in infected cell nuclei and chromatin: elongation of chromatin associated ribonucleic acid by Escherichia coli ribonucleic acid polymerase. Biochemistry. 1977 May 3; 16(9):1795-801.
    View in: PubMed
  168. Troxler DH, Boyars JK, Parks WP, Scolnick EM. Friend strain of spleen focus-forming virus: a recombinant between mouse type C ecotropic viral sequences and sequences related to xenotropic virus. J Virol. 1977 May; 22(2):361-72.
    View in: PubMed
  169. Troxler DH, Parks WP, Vass WC, Scolnick EM. Isolation of a fibroblast nonproducer cell line containing the Friend strain of the spleen focus-forming virus. Virology. 1977 Feb; 76(2):602-15.
    View in: PubMed
  170. Young HA, Shih TY, Scolnick EM, Parks WP. Steroid induction of mouse mammary tumor virus: effect upon synthesis and degradation of viral RNA. J Virol. 1977 Jan; 21(1):139-46.
    View in: PubMed
  171. Scolnick EM, Williams D, Parks WP. Purification and characterisation of viral RNA of a sarcoma virus isolated from a woolly monkey. Nature. 1976 Dec 23-30; 264(5588):809-11.
    View in: PubMed
  172. Scolnick EM, Williams D, Maryak J, Vass W, Goldberg RJ, Parks WP. Type C particle-positive and type C particle-negative rat cell lines: characterization of the coding capacity of endogenous sarcoma virus-specific RNA. J Virol. 1976 Dec; 20(3):570-82.
    View in: PubMed
  173. Levin R, Ruscetti SK, Parks WP, Scolnick EM. Expression of feline type-C virus in normal and tumor tissues of the domestic cat. Int J Cancer. 1976 Nov 15; 18(5):661-71.
    View in: PubMed
  174. Holland JJ, Villarreal LP, Welsh RM, Oldstone MB, Kohne D, Lazzarini R, Scolnick E. Long-term persistent vesicular stomatitis virus and rabies virus infection of cells in vitro. J Gen Virol. 1976 Nov; 33(2):193-211.
    View in: PubMed
  175. Peebles PT, Scolnick EM, Howk RS. Increased sarcoma virus RNA in cells transformed by leukemia viruses: model for leukemogenesis. Science. 1976 Jun 11; 192(4244):1143-5.
    View in: PubMed
  176. Parks WP, Howk RS, Anisowicz A, Scolnick EM. Deletion mapping of moloney type C virus: polypeptide and nucleic acid expression in different transforming virus isolates. J Virol. 1976 May; 18(2):491-503.
    View in: PubMed
  177. Parks WP, Hubbell ES, Goldberg RJ, O'Neill FJ, Scolnick EM. High frequency variation in mammary tumor virus expression in cell culture. Cell. 1976 May; 8(1):87-93.
    View in: PubMed
  178. Scolnick EM, Goldberg RJ, Williams D. Characterizatiion of rat genetic sequences of Kirsten sarcoma virus: distinct class of endogenous rat type C viral sequences. J Virol. 1976 May; 18(2):559-66.
    View in: PubMed
  179. Peebles PT, Gerwin BI, Scolnick EM. Murine sarcoma virus defectiveness: serological detection of only helper virus reverse transcriptase in sarcoma virus rescued from nonmurine S + L-cells. Virology. 1976 Apr; 70(2):313-23.
    View in: PubMed
  180. Scolnick EM, Young HA, Parks WP. Biochemical and physiological mechanisms in glucocorticoid hormone induction of mouse mammary tumor virus. Virology. 1976 Jan; 69(1):148-56.
    View in: PubMed
  181. Scolnick EM, Howk RS, Anisowicz A, Peebles PT, Scher CD, Parks WP. Separation of sarcoma virus-specific and leukemia virus-specific genetic sequences of Moloney sarcoma virus. Proc Natl Acad Sci U S A. 1975 Nov; 72(11):4650-4.
    View in: PubMed
  182. Maisel J, Scolnick EM, Duesberg P. Base sequence differences between the RNA components of Harvey sarcoma virus. J Virol. 1975 Sep; 16(3):749-53.
    View in: PubMed
  183. Young HA, Parks WP, Scolnick EM. Effect of chemical inactivating agents on glucocorticoid receptor proteins in mouse and hamster cells. Proc Natl Acad Sci U S A. 1975 Aug; 72(8):3060-4.
    View in: PubMed
  184. Scher CD, Scolnick EM, Siegler R. Induction of erythroid leukaemia by Harvey and Kirsten sarcoma viruses. Nature. 1975 Jul 17; 256(5514):225-6.
    View in: PubMed
  185. Parks WP, Noon MC, Gilden R, Scolnick EM. Serological studies with low-molecular-weight polypeptides from the Moloney strain of murine leukemia virus. J Virol. 1975 Jun; 15(6):1385-95.
    View in: PubMed
  186. Parks WP, Ransom JC, Young HA, Scolnick EM. Mammary tumor virus induction by glucocorticoids. Characterization of specific transcriptional regulation. J Biol Chem. 1975 May 10; 250(9):3330-6.
    View in: PubMed
  187. Young HA, Scolnick EM, Parks WP. Glucocorticoid-receptor interaction and induction of murine mammary tumor virus. J Biol Chem. 1975 May 10; 250(9):3337-43.
    View in: PubMed
  188. Scolnick EM, Bumgarner SJ. Isolation of infectious xenotropic mouse type C virus by transfection of a heterologous cell with DNA from a transformed mouse cell. J Virol. 1975 May; 15(5):1293-6.
    View in: PubMed
  189. Parks WP, Scolnick EM, Ransom JC. Glucocorticoid induction of murine mammary tumor virus in vitro. Cold Spring Harb Symp Quant Biol. 1975; 39 Pt 2:1151-8.
    View in: PubMed
  190. Goldberg RJ, Levin R, Parks WP, Scolnick EM. Quantitative analysis of the rescue of RNA sequences by mammalian type C viruses. J Virol. 1975 Jan; 17(1):43-50.
    View in: PubMed
  191. Goldberg RJ, Scolnick EM, Parks WP, Yakovleva LA, Lapin BA. Isolation of a primate type-C virus from a lymphomatous baboon. Int J Cancer. 1974 Dec 15; 14(6):722-30.
    View in: PubMed
  192. Scolnick EM, Maryak JM, Parks WP. Levels of rat cellular RNA homologous to either Kirsten sarcoma virus or rat type-C virus in cell lines derived from Osborne-Mendel rats. J Virol. 1974 Dec; 14(6):1435-44.
    View in: PubMed
  193. Parks WP, Scolnick EM, Noon MC, Watson CJ. Immunological cross-reactions between two low-molecular-weight polypeptides from a murine type C virus. J Virol. 1974 Sep; 14(3):430-3.
    View in: PubMed
  194. Howk RS, Williams DR, Haberman AB, Parks WP, Scolnick EM. A comparison of the transcription of mouse cell chromatin by homologous RNA polymerase I and II. Cell. 1974 Sep; 3(1):15-22.
    View in: PubMed
  195. Parks WP, Howk RS, Scolnick EM, Oroszlan S, Gilden RV. Immunochemical characterization of two major polypeptides from murine mammary tumor virus. J Virol. 1974 Jun; 13(6):1200-10.
    View in: PubMed
  196. Scolnick EM, Parks WP. Harvey sarcoma virus: a second murine type C sarcoma virus with rat genetic information. J Virol. 1974 Jun; 13(6):1211-9.
    View in: PubMed
  197. Scolnick EM, Parks WP. Host range studies on xenotropic type C viruses in somatic cell hybrids. Virology. 1974 May; 59(1):168-78.
    View in: PubMed
  198. Parks WP, Scolnick EM, Kozikowski EH. Dexamethasone stimulation of murine mammary tumor virus expression: a tissue culture source of virus. Science. 1974 Apr 12; 184(4133):158-60.
    View in: PubMed
  199. Scolnick EM, Parks W, Kawakami T, Kohne D, Okabe H, Gilden R, Hatanaka M. Primate and murine type-C viral nucleic acid association kinetics: analysis of model systems and natural tissues. J Virol. 1974 Feb; 13(2):363-9.
    View in: PubMed
  200. Scolnick EM, Parks WP. Identification of viral reverse-transcriptase. Methods Enzymol. 1974; 29:130-43.
    View in: PubMed
  201. Parks WP, Gilden RV, Bykovsky AF, Miller GG, Zhdanov VM, Soloviev VD, Scolnick EM. Mason-Pfizer virus characterization: a similar virus in a human amniotic cell line. J Virol. 1973 Dec; 12(6):1540-7.
    View in: PubMed
  202. Benveniste RE, Todaro GJ, Scolnick EM, Parks WP. Partial transcription of murine type C viral genomes in BALB c cell lines. J Virol. 1973 Oct; 12(4):711-20.
    View in: PubMed
  203. Scolnick EM, Rands E, Williams D, Parks WP. Studies on the nucleic acid sequences of Kirsten sarcoma virus: a model for formation of a mammalian RNA-containing sarcoma virus. J Virol. 1973 Sep; 12(3):458-63.
    View in: PubMed
  204. Parks WP, Scolnick EM. Murine mammary tumor cell clones with varying degrees of virus expression. Virology. 1973 Sep; 55(1):163-73.
    View in: PubMed
  205. Parks WP, Scolnick EM, Noon MC, Watson CJ, Kawakami TG. Radioimmunoassay of mammalian type-C polypeptides. IV. Characterization of woolly monkey and gibbon viral antigens. Int J Cancer. 1973 Jul 15; 12(1):129-37.
    View in: PubMed
  206. Scolnick EM, Parks WP. Isolation and characterization of a primate sarcoma virus: mechanism of rescue. Int J Cancer. 1973 Jul 15; 12(1):138-47.
    View in: PubMed
  207. Howk RS, Rye LA, Killeen LA, Scolnick EM, Parks WP. Characterization and separation of viral DNA polymerase in mouse milk. Proc Natl Acad Sci U S A. 1973 Jul; 70(7):2117-21.
    View in: PubMed
  208. Scolnick EM, Benveniste R, Parks WP. Purification by oligo(dT)-cellulose of viral-specific RNA from sarcoma virus-transformed mammalian nonproducer cells. J Virol. 1973 Apr; 11(4):600-2.
    View in: PubMed
  209. Parks WP, Livingston DM, Todaro GJ, Benveniste RE, Scolnick EM. Radioimmunoassay of mammalian type C viral proteins. 3. Detection of viral antigen in normal murine cells and tissues. J Exp Med. 1973 Mar 1; 137(3):622-35.
    View in: PubMed
  210. Benveniste RE, Scolnick EM. RNA in mammalian sarcoma virus transformed nonproducer cells homologous to murine leukemia virus RNA. Virology. 1973 Feb; 51(2):370-82.
    View in: PubMed
  211. Todaro GJ, Scolnick EM, Parks WP, Livingston DM, Aaronson SA. Detection of type C viruses in normal and transformed cells. Johns Hopkins Med J Suppl. 1973; 2:231-44.
    View in: PubMed
  212. Todaro GJ, Aaronson SA, Scolnick EM, Ross J, Parks WP. Reverse transcriptases of RNA tumor viruses: immunological relationships. Bibl Haematol. 1973; 39:269-71.
    View in: PubMed
  213. Livingston DM, Parks WP, Scolnick EM, Ross J. Affinity chromatography of avian type C viral reverse transcriptase: studies with Rous sarcoma virus transformed rat cells. Virology. 1972 Nov; 50(2):388-95.
    View in: PubMed
  214. Tronick SR, Scolnick EM, Parks WP. Reversible inactivation of the deoxyribonucleic acid polymerase of Rauscher leukemia virus. J Virol. 1972 Oct; 10(4):885-8.
    View in: PubMed
  215. Scolnick EM, Stephenson JR, Aaronson SA. Isolation of temperature-sensitive mutants of murine sarcoma virus. J Virol. 1972 Oct; 10(4):653-7.
    View in: PubMed
  216. Scolnick EM, Parks WP, Todaro GJ. Reverse transcriptases of primate viruses as immunological markers. Science. 1972 Sep 22; 177(4054):1119-21.
    View in: PubMed
  217. Scolnick EM, Parks WP, Livingston DM. Radioimmunoassay of mammalian type C viral proteins. I. Species specific reactions of murine and feline viruses. J Immunol. 1972 Sep; 109(3):570-7.
    View in: PubMed
  218. Ross J, Tronick SR, Scolnick EM. Polyadenylate rich RNA in the 70 S RNA of murine leukemia-sarcoma virus. Virology. 1972 Jul; 49(1):230-5.
    View in: PubMed
  219. Parks WP, Scolnick EM. Radioimmunoassay of mammalian type-C viral proteins: interspecies antigenic reactivities of the major internal polypeptide. Proc Natl Acad Sci U S A. 1972 Jul; 69(7):1766-70.
    View in: PubMed
  220. Stephenson JR, Scolnick EM, Aaronson SA. Genetic stability of the sarcoma viruses in murine and avian sarcoma virus-transformed nonproducer cells. Int J Cancer. 1972 May 15; 9(3):577-83.
    View in: PubMed
  221. Livingston DM, Scolnick EM, Parks WP, Todaro GT. Affinity chromatography of RNA-dependent DNA polymerase from RNA tumor viruses on a solid phase immunoadsorbent. Proc Natl Acad Sci U S A. 1972 Feb; 69(2):393-7.
    View in: PubMed
  222. Scolnick EM, Parks WP, Todaro GJ, Aaronson SA. Immunological characterization of primate C-type virus reverse transcriptases. Nat New Biol. 1972 Jan 12; 235(54):35-40.
    View in: PubMed
  223. Ross J, Aviv H, Scolnick E, Leder P. In vitro synthesis of DNA complementary to purified rabbit globin mRNA (RNA-dependent DNA polymerase-reticulocyte-hemoglobin-density gradient centrifugation-oligo(dT) primer). Proc Natl Acad Sci U S A. 1972 Jan; 69(1):264-8.
    View in: PubMed
  224. Parks WP, Scolnick EM, Ross J, Todaro GJ, Aaronson SA. Immunological relationships of reverse transcriptases from ribonucleic acid tumor viruses. J Virol. 1972 Jan; 9(1):110-5.
    View in: PubMed
  225. Caskey CT, Beaudet AL, Scolnick EM, Rosman M. Hydrolysis of fMet-tRNA by peptidyl transferase. Proc Natl Acad Sci U S A. 1971 Dec; 68(12):3163-7.
    View in: PubMed
  226. Aaronson SA, Todaro GJ, Scolnick EM. Induction of murine C-type viruses from clonal lines of virus-free BALB-3T3 cells. Science. 1971 Oct 8; 174(4005):157-9.
    View in: PubMed
  227. Scolnick EM. "Reverse transcriptase" in higher cells. Dev Biol. 1971 Sep; 26(1):175-6.
    View in: PubMed
  228. Ross J, Scolnick EM, Todaro GJ, Aaronson SA. Separation of murine cellular and murine leukaemia virus DNA polymerases. Nat New Biol. 1971 Jun 9; 231(23):163-7.
    View in: PubMed
  229. Aaronson SA, Parks WP, Scolnick EM, Todaro GJ. Antibody to the RNA-dependent DNA polymerase of mammalian C-type RNA tumor viruses. Proc Natl Acad Sci U S A. 1971 May; 68(5):920-4.
    View in: PubMed
  230. Scolnick EM, Aaronson SA, Todaro GJ, Parks WP. RNA dependent DNA polymerase activity in mammalian cells. Nature. 1971 Jan 29; 229(5283):318-21.
    View in: PubMed
  231. Parks WP, Todaro GJ, Scolnick EM, Aaronson SA. RNA dependent DNA polymerase in primate syncytium-forming (foamy) viruses. Nature. 1971 Jan 22; 229(5282):258-60.
    View in: PubMed
  232. Stone LB, Scolnick E, Takemoto KK, Aaronson SA. Visna virus: a slow virus with an RNA dependent DNA polymerase. Nature. 1971 Jan 22; 229(5282):257-8.
    View in: PubMed
  233. Scolnick E, Rands E, Aaronson SA, Todaro GJ. RNA-dependent DNA polymerase activity in five RNA viruses: divalent cation requirements. Proc Natl Acad Sci U S A. 1970 Dec; 67(4):1789-96.
    View in: PubMed
  234. Gerwin BI, Todaro GJ, Zeve V, Scolnick EM, Aaronson SA. Separation of RNA-dependent DNA polymerase activity from the murine leukaemia virion. Nature. 1970 Oct 31; 228(5270):435-8.
    View in: PubMed
  235. Scolnick EM, Aaronson SA, Todaro GJ. DNA synthesis by RNA-containing tumor viruses. Proc Natl Acad Sci U S A. 1970 Oct; 67(2):1034-41.
    View in: PubMed
  236. Tompkins RK, Scolnick EM, Caskey CT. Peptide chain termination. VII. The ribosomal and release factor requirements for peptide release. Proc Natl Acad Sci U S A. 1970 Mar; 65(3):702-8.
    View in: PubMed
  237. Goldstein J, Milman G, Scolnick E, Caskey T. Peptide chain termination. VI. Purification and site of action of S. Proc Natl Acad Sci U S A. 1970 Feb; 65(2):430-7.
    View in: PubMed
  238. Scolnick E, Milman G, Rosman M, Caskey T. Transesterification by peptidyl transferase. Nature. 1970 Jan 10; 225(5228):152-4.
    View in: PubMed
  239. Scolnick EM, Caskey CT. Peptide chain termination. V. The role of release factors in mRNA terminator codon recognition. Proc Natl Acad Sci U S A. 1969 Dec; 64(4):1235-41.
    View in: PubMed
  240. Scolnick EM, Caskey CT. Genetic punctuation signals. Lancet. 1969 Sep 13; 2(7620):597.
    View in: PubMed
  241. Milman G, Goldstein J, Scolnick E, Caskey T. Peptide chain termination. 3. Stimulation of in vitro termination. Proc Natl Acad Sci U S A. 1969 May; 63(1):183-90.
    View in: PubMed
  242. Pestka S, Scolnick EM, Heck BH. A convenient assay for mono-, di-, and oligophenylalanines. Anal Biochem. 1969 Apr 4; 28(1):375-84.
    View in: PubMed
  243. Caskey T, Scolnick E, Tompkins R, Goldstein J, Milman G. Peptide chain termination, codon, protein factor, and ribosomal requirements. Cold Spring Harb Symp Quant Biol. 1969; 34:479-88.
    View in: PubMed
  244. Caskey CT, Tompkins R, Scolnick E, Caryk T, Nirenberg M. Sequential translation of trinucleotide codons for the initiation and termination of protein synthesis. Science. 1968 Oct 4; 162(3849):135-8.
    View in: PubMed
  245. Scolnick E, Tompkins R, Caskey T, Nirenberg M. Release factors differing in specificity for terminator codons. Proc Natl Acad Sci U S A. 1968 Oct; 61(2):768-74.
    View in: PubMed
  246. Lang DJ, Scolnick EM, Willerson JT. Association of cytomegalovirus infection with the postperfusion syndrome. N Engl J Med. 1968 May 23; 278(21):1147-9.
    View in: PubMed
  247. Deykin D, Pritzker CR, Scolnick EM. Plasma co-factors in adenosine diphosphate-induced aggregation of human platelets. Nature. 1965 Oct 16; 208(5007):296-8.
    View in: PubMed
  248. SCOLNICK EM, LIN EC. Parallel induction of D-arabitol and D-sorbitol dehydrogenases. J Bacteriol. 1962 Oct; 84:631-7.
    View in: PubMed
Local representatives can answer questions about the Profiles website or help with editing a profile or issues with profile data. For assistance with this profile: HMS/HSDM faculty should contact Human Resources at faculty_serviceshms.harvard.edu.
Scolnick's Networks
Click the "See All" links for more information and interactive visualizations!
Concepts
_
Co-Authors
_
Similar People
_
Same Department
Physical Neighbors
_