 Scott A. Hilderbrand, PH.D.
| Title | Instructor in Radiology |
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| Institution | Massachusetts General Hospital |
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| Department | Radiology |
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| Address | Massachusetts General Hospital
Ctr. for Molecular Imaging Research, Rm. 5406
149 13th Street
Charlestown MA 02129
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| Phone | 617/726-5788 |
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 Bibliographic
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications.
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Tassa C, Liong M, Hilderbrand S, Sandler JE, Reiner T, Keliher EJ, Weissleder R, Shaw SY. On-chip bioorthogonal chemistry enables immobilization of in situ modified nanoparticles and small molecules for label-free monitoring of protein binding and reaction kinetics. Lab Chip. 2012 Sep 7; 12(17):3103-10.
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Hendricks JA, Keliher EJ, Wan D, Hilderbrand SA, Weissleder R, Mazitschek R. Synthesis of [18F]BODIPY: bifunctional reporter for hybrid optical/positron emission tomography imaging. Angew Chem Int Ed Engl. 2012 May 7; 51(19):4603-6.
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Karver MR, Weissleder R, Hilderbrand SA. Bioorthogonal reaction pairs enable simultaneous, selective, multi-target imaging. Angew Chem Int Ed Engl. 2012 Jan 23; 51(4):920-2.
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Karver MR, Weissleder R, Hilderbrand SA. Synthesis and evaluation of a series of 1,2,4,5-tetrazines for bioorthogonal conjugation. Bioconjug Chem. 2011 Nov 16; 22(11):2263-70.
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Yoon TJ, Lee H, Shao H, Hilderbrand SA, Weissleder R. Multicore assemblies potentiate magnetic properties of biomagnetic nanoparticles. Adv Mater. 2011 Nov 2; 23(41):4793-7.
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Zeglis BM, Mohindra P, Weissmann GI, Divilov V, Hilderbrand SA, Weissleder R, Lewis JS. Modular strategy for the construction of radiometalated antibodies for positron emission tomography based on inverse electron demand Diels-Alder click chemistry. Bioconjug Chem. 2011 Oct 19; 22(10):2048-59.
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Keliher EJ, Reiner T, Turetsky A, Hilderbrand SA, Weissleder R. High-yielding, two-step 18F labeling strategy for 18F-PARP1 inhibitors. ChemMedChem. 2011 Mar 7; 6(3):424-7.
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Haun JB, Devaraj NK, Hilderbrand SA, Lee H, Weissleder R. Bioorthogonal chemistry amplifies nanoparticle binding and enhances the sensitivity of cell detection. Nat Nanotechnol. 2010 Sep; 5(9):660-5.
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Han HS, Devaraj NK, Lee J, Hilderbrand SA, Weissleder R, Bawendi MG. Development of a bioorthogonal and highly efficient conjugation method for quantum dots using tetrazine-norbornene cycloaddition. J Am Chem Soc. 2010 Jun 16; 132(23):7838-9.
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Devaraj NK, Hilderbrand S, Upadhyay R, Mazitschek R, Weissleder R. Bioorthogonal turn-on probes for imaging small molecules inside living cells. Angew Chem Int Ed Engl. 2010 Apr 6; 49(16):2869-72.
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Garanger E, Blois J, Hilderbrand SA, Shao F, Josephson L. Divergent oriented synthesis for the design of reagents for protein conjugation. J Comb Chem. 2010 Jan-Feb; 12(1):57-64.
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Hilderbrand SA. Labels and probes for live cell imaging: overview and selection guide. Methods Mol Biol. 2010; 591:17-45.
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Panizzi P, Nahrendorf M, Wildgruber M, Waterman P, Figueiredo JL, Aikawa E, McCarthy J, Weissleder R, Hilderbrand SA. Oxazine conjugated nanoparticle detects in vivo hypochlorous acid and peroxynitrite generation. J Am Chem Soc. 2009 Nov 4; 131(43):15739-44.
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Hilderbrand SA, Weissleder R. Near-infrared fluorescence: application to in vivo molecular imaging. Curr Opin Chem Biol. 2010 Feb; 14(1):71-9.
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Vinegoni C, Razansky D, Hilderbrand SA, Shao F, Ntziachristos V, Weissleder R. Transillumination fluorescence imaging in mice using biocompatible upconverting nanoparticles. Opt Lett. 2009 Sep 1; 34(17):2566-8.
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Hilderbrand SA, Shao F, Salthouse C, Mahmood U, Weissleder R. Upconverting luminescent nanomaterials: application to in vivo bioimaging. Chem Commun (Camb). 2009 Jul 28; (28):4188-90.
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Garanger E, Hilderbrand SA, Blois JT, Sosnovik DE, Weissleder R, Josephson L. A DNA-binding Gd chelate for the detection of cell death by MRI. Chem Commun (Camb). 2009 Aug 7; (29):4444-6.
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Devaraj NK, Upadhyay R, Haun JB, Hilderbrand SA, Weissleder R. Fast and sensitive pretargeted labeling of cancer cells through a tetrazine/trans-cyclooctene cycloaddition. Angew Chem Int Ed Engl. 2009; 48(38):7013-6.
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Shao F, Weissleder R, Hilderbrand SA. Monofunctional carbocyanine dyes for bio- and bioorthogonal conjugation. Bioconjug Chem. 2008 Dec; 19(12):2487-91.
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Devaraj NK, Weissleder R, Hilderbrand SA. Tetrazine-based cycloadditions: application to pretargeted live cell imaging. Bioconjug Chem. 2008 Dec; 19(12):2297-9.
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Hilderbrand SA, Kelly KA, Niedre M, Weissleder R. Near infrared fluorescence-based bacteriophage particles for ratiometric pH imaging. Bioconjug Chem. 2008 Aug; 19(8):1635-9.
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Bouffard J, Kim Y, Swager TM, Weissleder R, Hilderbrand SA. A highly selective fluorescent probe for thiol bioimaging. Org Lett. 2008 Jan 3; 10(1):37-40.
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Shepherd J, Hilderbrand SA, Waterman P, Heinecke JW, Weissleder R, Libby P. A fluorescent probe for the detection of myeloperoxidase activity in atherosclerosis-associated macrophages. Chem Biol. 2007 Nov; 14(11):1221-31.
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Hilderbrand SA, Weissleder R. Optimized pH-responsive cyanine fluorochromes for detection of acidic environments. Chem Commun (Camb). 2007 Jul 14; (26):2747-9.
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Kim Y, Hilderbrand SA, Weissleder R, Tung CH. Sugar sensing based on induced pH changes. Chem Commun (Camb). 2007 Jun 14; (22):2299-301.
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Galande AK, Hilderbrand SA, Weissleder R, Tung CH. Enzyme-targeted fluorescent imaging probes on a multiple antigenic peptide core. J Med Chem. 2006 Jul 27; 49(15):4715-20.
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Hilderbrand SA, Kelly KA, Weissleder R, Tung CH. Monofunctional near-infrared fluorochromes for imaging applications. Bioconjug Chem. 2005 Sep-Oct; 16(5):1275-81.
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Hilderbrand SA, Lippard SJ. Nitric oxide reactivity of fluorophore coordinated carboxylate-bridged diiron(II) and dicobalt(II) complexes. Inorg Chem. 2004 Aug 23; 43(17):5294-301.
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Hilderbrand SA, Lippard SJ. Cobalt chemistry with mixed aminotroponiminate salicylaldiminate ligands: synthesis, characterization, and nitric oxide reactivity. Inorg Chem. 2004 Jul 26; 43(15):4674-82.
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Hilderbrand SA, Lim MH, Lippard SJ. Dirhodium tetracarboxylate scaffolds as reversible fluorescence-based nitric oxide sensors. J Am Chem Soc. 2004 Apr 21; 126(15):4972-8.
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Nolan EM, Burdette SC, Harvey JH, Hilderbrand SA, Lippard SJ. Synthesis and characterization of zinc sensors based on a monosubstituted fluorescein platform. Inorg Chem. 2004 Apr 19; 43(8):2624-35.
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