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Mark Edward Alexander, M.D.

TitleAssistant Professor of Pediatrics
InstitutionChildren's Hospital Boston
DepartmentPediatrics
AddressChildrens Hospital
Cardiology, Bader 268
300 Longwood Ave
Boston MA 02115
Phone617/355-6152
Fax617/739-9058

 Bibliographic 
 selected publications
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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  1. Zachariah JP, Walsh EP, Triedman JK, Berul CI, Cecchin F, Alexander ME, Bevilacqua LM. Multiple accessory pathways in the young: The impact of structural heart disease. Am Heart J. 2013 Jan; 165(1):87-92.
    View in: PubMed
  2. Eisenberg MA, Green-Hopkins I, Alexander ME, Chiang VW. Cardiac troponin T as a screening test for myocarditis in children. Pediatr Emerg Care. 2012 Nov; 28(11):1173-8.
    View in: PubMed
  3. Radbill AE, Triedman JK, Berul CI, Walsh EP, Alexander ME, Webster G, Cecchin F. Prospective Evaluation of Defibrillation Threshold and Postshock Rhythm in Young ICD Recipients. Pacing Clin Electrophysiol. 2012 Dec; 35(12):1487-93.
    View in: PubMed
  4. Zachariah JP, Colan SD, Lang P, Triedman JK, Alexander ME, Walsh EP, Berul CI, Cecchin F. Circulating matrix metalloproteinases in adolescents with hypertrophic cardiomyopathy and ventricular arrhythmia. Circ Heart Fail. 2012 Jul 1; 5(4):462-6.
    View in: PubMed
  5. Leslie LK, Cohen JT, Newburger JW, Alexander ME, Wong JB, Sherwin ED, Rodday AM, Parsons SK, Triedman JK. Costs and benefits of targeted screening for causes of sudden cardiac death in children and adolescents. Circulation. 2012 May 29; 125(21):2621-9.
    View in: PubMed
  6. Rodday AM, Triedman JK, Alexander ME, Cohen JT, Ip S, Newburger JW, Parsons SK, Trikalinos TA, Wong JB, Leslie LK. Electrocardiogram screening for disorders that cause sudden cardiac death in asymptomatic children: a meta-analysis. Pediatrics. 2012 Apr; 129(4):e999-1010.
    View in: PubMed
  7. Batra AS, Alexander ME, Silka MJ. Attention-deficit/hyperactivity disorder, stimulant therapy, and the patient with congenital heart disease: evidence and reason. Pediatr Cardiol. 2012 Mar; 33(3):394-401.
    View in: PubMed
  8. Saleeb SF, Margossian R, Spencer CT, Alexander ME, Smoot LB, Dorfman AL, Bergersen L, Gauvreau K, Marx GR, Colan SD. Reproducibility of echocardiographic diagnosis of left ventricular noncompaction. J Am Soc Echocardiogr. 2012 Feb; 25(2):194-202.
    View in: PubMed
  9. Miyake CY, Del Nido PJ, Alexander ME, Cecchin F, Berul CI, Triedman JK, Geva T, Walsh EP. Cardiac tumors and associated arrhythmias in pediatric patients, with observations on surgical therapy for ventricular tachycardia. J Am Coll Cardiol. 2011 Oct 25; 58(18):1903-9.
    View in: PubMed
  10. Alexander ME. Exercise, stand up, flip a coin, or just say no: provocative testing in the child with borderline QTc. Circ Arrhythm Electrophysiol. 2011 Aug; 4(4):422-3.
    View in: PubMed
  11. Mah D, Wang A, Wu A, Alexander ME, Walsh EP. Marked QT prolongation and ventricular tachycardia of a transient nature in young children with cardiomyopathy. Pacing Clin Electrophysiol. 2012 Aug; 35(8):e247-50.
    View in: PubMed
  12. Mah DY, Alexander ME, Cecchin F, Walsh EP, Triedman JK. The electroanatomic mechanisms of atrial tachycardia in patients with tetralogy of Fallot and double outlet right ventricle. J Cardiovasc Electrophysiol. 2011 Sep; 22(9):1013-7.
    View in: PubMed
  13. Singh TP, Alexander ME, Gauvreau K, Curran T, Rhodes Y, Rhodes J. Recovery of oxygen consumption after maximal exercise in children. Med Sci Sports Exerc. 2011 Apr; 43(4):555-9.
    View in: PubMed
  14. Fernandes SM, Alexander ME, Graham DA, Khairy P, Clair M, Rodriguez E, Pearson DD, Landzberg MJ, Rhodes J. Exercise testing identifies patients at increased risk for morbidity and mortality following Fontan surgery. Congenit Heart Dis. 2011 Jul-Aug; 6(4):294-303.
    View in: PubMed
  15. Lin AE, Alexander ME, Colan SD, Kerr B, Rauen KA, Noonan J, Baffa J, Hopkins E, Sol-Church K, Limongelli G, Digilio MC, Marino B, Innes AM, Aoki Y, Silberbach M, Delrue MA, White SM, Hamilton RM, O'Connor W, Grossfeld PD, Smoot LB, Padera RF, Gripp KW. Clinical, pathological, and molecular analyses of cardiovascular abnormalities in Costello syndrome: a Ras/MAPK pathway syndrome. Am J Med Genet A. 2011 Mar; 155A(3):486-507.
    View in: PubMed
  16. Miyake CY, Mah DY, Atallah J, Oikle HP, Melgar ML, Alexander ME, Berul CI, Cecchin F, Walsh EP, Triedman JK. Nonfluoroscopic imaging systems reduce radiation exposure in children undergoing ablation of supraventricular tachycardia. Heart Rhythm. 2011 Apr; 8(4):519-25.
    View in: PubMed
  17. Cecchin F, Atallah J, Walsh EP, Triedman JK, Alexander ME, Berul CI. Lead extraction in pediatric and congenital heart disease patients. Circ Arrhythm Electrophysiol. 2010 Oct; 3(5):437-44.
    View in: PubMed
  18. DiVasta AD, Walls CE, Feldman HA, Quach AE, Woods ER, Gordon CM, Alexander ME. Malnutrition and hemodynamic status in adolescents hospitalized for anorexia nervosa. Arch Pediatr Adolesc Med. 2010 Aug; 164(8):706-13.
    View in: PubMed
  19. Triedman JK, Alexander ME. Needle in a haystack: modeling the incidence of sudden cardiac arrest in healthy children. Circulation. 2010 Mar 23; 121(11):1283-5.
    View in: PubMed
  20. Radbill AE, Triedman JK, Berul CI, Fynn-Thompson F, Atallah J, Alexander ME, Walsh EP, Cecchin F. System survival of nontransvenous implantable cardioverter-defibrillators compared to transvenous implantable cardioverter-defibrillators in pediatric and congenital heart disease patients. Heart Rhythm. 2010; 7(2):193-8.
    View in: PubMed
  21. Takahashi K, Cecchin F, Fortescue E, Berul CI, Alexander ME, Walsh EP, Fynn-Thompson F, Triedman JK. Permanent atrial pacing lead implant route after Fontan operation. Pacing Clin Electrophysiol. 2009 Jun; 32(6):779-85.
    View in: PubMed
  22. Costello JM, Alexander ME, Greco KM, Perez-Atayde AR, Laussen PC. Lyme carditis in children: presentation, predictive factors, and clinical course. Pediatrics. 2009 May; 123(5):e835-41.
    View in: PubMed
  23. Alexander ME. Orthostasis, the autonomic nervous system, and abdominal pain in children: is there a relation between postural orthostatic tachycardia and recurrent abdominal pain? J Pediatr Gastroenterol Nutr. 2008 Nov; 47(5):696-700.
    View in: PubMed
  24. Leslie LK, Alexander ME, Trikalinos TA, Cohen JT, Parsons SK, Newburger JW. Reexamining the emperor's new clothes: ambiguities in current cardiac screening recommendations for youth with attention deficit hyperactivity disorder. Circ Cardiovasc Qual Outcomes. 2008 Nov; 1(2):134-7.
    View in: PubMed
  25. Radbill AE, Brown DW, Lacro RV, Cecchin F, Berul CI, Triedman JK, Bevilacqua LM, Walsh EP, Alexander ME. Ascending aortic dilation in patients with congenital complete heart block. Heart Rhythm. 2008 Dec; 5(12):1704-8.
    View in: PubMed
  26. Cecchin F, Frangini PA, Brown DW, Fynn-Thompson F, Alexander ME, Triedman JK, Gauvreau K, Walsh EP, Berul CI. Cardiac resynchronization therapy (and multisite pacing) in pediatrics and congenital heart disease: five years experience in a single institution. J Cardiovasc Electrophysiol. 2009 Jan; 20(1):58-65.
    View in: PubMed
  27. Kipps A, Alexander M, Colan SD, Gauvreau K, Smoot L, Crawford L, Darras BT, Blume ED. The longitudinal course of cardiomyopathy in Friedreich's ataxia during childhood. Pediatr Cardiol. 2009 Apr; 30(3):306-10.
    View in: PubMed
  28. Mahajan T, Berul CI, Cecchin F, Triedman JK, Alexander ME, Walsh EP. Atrioventricular nodal reentrant tachycardia with 2:1 block in pediatric patients. Heart Rhythm. 2008 Oct; 5(10):1391-5.
    View in: PubMed
  29. Berul CI, Van Hare GF, Kertesz NJ, Dubin AM, Cecchin F, Collins KK, Cannon BC, Alexander ME, Triedman JK, Walsh EP, Friedman RA. Results of a multicenter retrospective implantable cardioverter-defibrillator registry of pediatric and congenital heart disease patients. J Am Coll Cardiol. 2008 Apr 29; 51(17):1685-91.
    View in: PubMed
  30. Mong S, Pomeroy SL, Cecchin F, Juraszek A, Alexander ME. Cardiac risk after craniopharyngioma therapy. Pediatr Neurol. 2008 Apr; 38(4):256-60.
    View in: PubMed
  31. Webster G, Jordao L, Martuscello M, Mahajan T, Alexander ME, Cecchin F, Triedman JK, Walsh EP, Berul CI. Digital music players cause interference with interrogation telemetry for pacemakers and implantable cardioverter-defibrillators without affecting device function. Heart Rhythm. 2008 Apr; 5(4):545-50.
    View in: PubMed
  32. Frangini PA, Cecchin F, Jordao L, Martuscello M, Alexander ME, Triedman JK, Walsh EP, Berul CI. How revealing are insertable loop recorders in pediatrics? Pacing Clin Electrophysiol. 2008 Mar; 31(3):338-43.
    View in: PubMed
  33. Webster G, Margossian R, Alexander ME, Cecchin F, Triedman JK, Walsh EP, Berul CI. Impact of transvenous ventricular pacing leads on tricuspid regurgitation in pediatric and congenital heart disease patients. J Interv Card Electrophysiol. 2008 Jan; 21(1):65-8.
    View in: PubMed
  34. Alexander ME, Cecchin F, Huang KP, Berul CI. Microvolt t-wave alternans with exercise in pediatrics and congenital heart disease: limitations and predictive value. Pacing Clin Electrophysiol. 2006 Jul; 29(7):733-41.
    View in: PubMed
  35. Bar-Cohen Y, Berul CI, Alexander ME, Fortescue EB, Walsh EP, Triedman JK, Cecchin F. Age, size, and lead factors alone do not predict venous obstruction in children and young adults with transvenous lead systems. J Cardiovasc Electrophysiol. 2006 Jul; 17(7):754-9.
    View in: PubMed
  36. Bar-Cohen Y, Khairy P, Morwood J, Alexander ME, Cecchin F, Berul CI. Inaccuracy of Wolff-Parkinson-white accessory pathway localization algorithms in children and patients with congenital heart defects. J Cardiovasc Electrophysiol. 2006 Jul; 17(7):712-6.
    View in: PubMed
  37. Seslar SP, Berul CI, Burklow TR, Cecchin F, Alexander ME. Transient prolonged corrected QT interval in Lyme disease. J Pediatr. 2006 May; 148(5):692-7.
    View in: PubMed
  38. Meier PM, Alexander ME, Sethna NF, De Jong-De Vos Van Steenwijk CC, Zurakowski D, Berde CB. Complex regional pain syndromes in children and adolescents: regional and systemic signs and symptoms and hemodynamic response to tilt table testing. Clin J Pain. 2006 May; 22(4):399-406.
    View in: PubMed
  39. Seslar SP, Alexander ME, Berul CI, Cecchin F, Walsh EP, Triedman JK. Ablation of nonautomatic focal atrial tachycardia in children and adults with congenital heart disease. J Cardiovasc Electrophysiol. 2006 Apr; 17(4):359-65.
    View in: PubMed
  40. Bar-Cohen Y, Cecchin F, Alexander ME, Berul CI, Triedman JK, Walsh EP. Cryoablation for accessory pathways located near normal conduction tissues or within the coronary venous system in children and young adults. Heart Rhythm. 2006 Mar; 3(3):253-8.
    View in: PubMed
  41. Alexander M. Entwining electrical and hypertrophic cardiomyopathies. Heart Rhythm. 2005 Dec; 2(12):1369-70.
    View in: PubMed
  42. Fortescue EB, Berul CI, Cecchin F, Walsh EP, Triedman JK, Alexander ME. Comparison of modern steroid-eluting epicardial and thin transvenous pacemaker leads in pediatric and congenital heart disease patients. J Interv Card Electrophysiol. 2005 Oct; 14(1):27-36.
    View in: PubMed
  43. Triedman JK, DeLucca JM, Alexander ME, Berul CI, Cecchin F, Walsh EP. Prospective trial of electroanatomically guided, irrigated catheter ablation of atrial tachycardia in patients with congenital heart disease. Heart Rhythm. 2005 Jul; 2(7):700-5.
    View in: PubMed
  44. Alexander ME. Transvenous pacing in infants: a faith based initiative? Pacing Clin Electrophysiol. 2004 Nov; 27(11):1463-5.
    View in: PubMed
  45. Morwood JG, Triedman JK, Berul CI, Khairy P, Alexander ME, Cecchin F, Walsh EP. Radiofrequency catheter ablation of ventricular tachycardia in children and young adults with congenital heart disease. Heart Rhythm. 2004 Sep; 1(3):301-8.
    View in: PubMed
  46. DiVasta AD, Alexander ME. Fainting freshmen and sinking sophomores: cardiovascular issues of the adolescent. Curr Opin Pediatr. 2004 Aug; 16(4):350-6.
    View in: PubMed
  47. Fortescue EB, Berul CI, Cecchin F, Walsh EP, Triedman JK, Alexander ME. Patient, procedural, and hardware factors associated with pacemaker lead failures in pediatrics and congenital heart disease. Heart Rhythm. 2004 Jul; 1(2):150-9.
    View in: PubMed
  48. Stephenson EA, Cecchin F, Alexander ME, Triedman JK, Walsh EP, Berul CI. Relation of right ventricular pacing in tetralogy of Fallot to electrical resynchronization. Am J Cardiol. 2004 Jun 1; 93(11):1449-52, A12.
    View in: PubMed
  49. Khairy P, Landzberg MJ, Gatzoulis MA, Lucron H, Lambert J, Marçon F, Alexander ME, Walsh EP. Value of programmed ventricular stimulation after tetralogy of fallot repair: a multicenter study. Circulation. 2004 Apr 27; 109(16):1994-2000.
    View in: PubMed
  50. Collins KK, Rhee EK, Delucca JM, Alexander ME, Bevilacqua LM, Berul CI, Walsh EP, Mayer JE, Jonas RA, del Nido PJ, Triedman JK. Modification to the Fontan procedure for the prophylaxis of intra-atrial reentrant tachycardia: short-term results of a prospective randomized blinded trial. J Thorac Cardiovasc Surg. 2004 Mar; 127(3):721-9.
    View in: PubMed
  51. Alexander ME, Cecchin F, Walsh EP, Triedman JK, Bevilacqua LM, Berul CI. Implications of implantable cardioverter defibrillator therapy in congenital heart disease and pediatrics. J Cardiovasc Electrophysiol. 2004 Jan; 15(1):72-6.
    View in: PubMed
  52. Mandapati R, Berul CI, Triedman JK, Alexander ME, Walsh EP. Radiofrequency catheter ablation of septal accessory pathways in the pediatric age group. Am J Cardiol. 2003 Oct 15; 92(8):947-50.
    View in: PubMed
  53. Stephenson EA, Casavant D, Tuzi J, Alexander ME, Law I, Serwer G, Strieper M, Walsh EP, Berul CI. Efficacy of atrial antitachycardia pacing using the Medtronic AT500 pacemaker in patients with congenital heart disease. Am J Cardiol. 2003 Oct 1; 92(7):871-6.
    View in: PubMed
  54. Ansari M, Alexander M, Tutar A, Massie BM. Incident cases of heart failure in a community cohort: importance and outcomes of patients with preserved systolic function. Am Heart J. 2003 Jul; 146(1):115-20.
    View in: PubMed
  55. Ansari M, Alexander M, Tutar A, Bello D, Massie BM. Cardiology participation improves outcomes in patients with new-onset heart failure in the outpatient setting. J Am Coll Cardiol. 2003 Jan 1; 41(1):62-8.
    View in: PubMed
  56. Stephenson EA, Collins KK, Dubin AM, Epstein MR, Hamilton RM, Kertesz NJ, Alexander ME, Cecchin F, Triedman JK, Walsh EP, Berul CI. Circadian and seasonal variation of malignant arrhythmias in a pediatric and congenital heart disease population. J Cardiovasc Electrophysiol. 2002 Oct; 13(10):1009-14.
    View in: PubMed
  57. Alexander M, Baker L, Clark C, McDonald KM, Rowell R, Saynina O, Hlatky MA. Management of ventricular arrhythmias in diverse populations in California. Am Heart J. 2002 Sep; 144(3):431-9.
    View in: PubMed
  58. Triedman JK, Alexander ME, Love BA, Collins KK, Berul CI, Bevilacqua LM, Walsh EP. Influence of patient factors and ablative technologies on outcomes of radiofrequency ablation of intra-atrial re-entrant tachycardia in patients with congenital heart disease. J Am Coll Cardiol. 2002 Jun 5; 39(11):1827-35.
    View in: PubMed
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